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human dignity has always been considered important and its maintenance has been emphasized ; it is recognized as the basis for human rights . it is so important that it is a subject long debated in medical professions , particularly nursing , and its maintenance has always been emphasized . because patients are vulne...
background : patient s dignity is an important issue which is highlighted in nursing it is an issue that is highly dependent on context and culture . heart disease is the most common disease in iran and the world . identification of facilitator and threatening patient dignity in heart patients is vital . this study...
immune reconstitution reactions are rare in pulmonary tuberculosis , especially in non - immunocompromised patients . we present a 21 year old immunocompetent patient that developed bilateral pneumothoraces and respiratory failure as a result of immune reconstitution syndrome during treatment for pulmonary tuberculos...
we present a young immunocompetent male with diagnosed sputum culture - positive tuberculosis on intensive phase with observed daily four - drug antituberculosis therapy . he presented at 1-month of treatment with sequential bilateral pneumothoraces , increase in cavitation and consolidation and respiratory failure ....
the online version of this article ( doi:10.1007/s13555 - 014 - 0055 - 0 ) contains supplementary material , which is available to authorized users . hypertrophic scarring is caused by an imbalance between extracellular matrix ( ecm ) protein deposition and degradation . there are many factors affecting surgical sc...
introductionthe objective of preventing surgical scar formation is to improve the quality of life for patients . many medical products have been used in preventing hypertrophic scarring but an optimal treatment method has not been established yet . at the present , there are several studies demonstrating the potent...
indicators of operative outcomes could be used to identify underperforming surgeons for support and training . pancreatic resection is one of the most common major operative procedures performed by hepato - pancreato - biliary ( hpb ) surgeons . as the procedure is complex with a high associated morbidity and morta...
background . indicators of operative outcomes could be used to identify underperforming surgeons for support and training . the feasibility of identifying hpb surgeons with poor operative performance ( outliers ) based on the results of pancreatic resections is not known . methods . a systematic review of medli...
adolescents psycho - social response to dancehall genre has become a national and public health concern , and has raised policy debate in terms of adolescent 's sexual and violent behavior ( with respect to pregnancy , sexually transmitted infections ( sti ) and human immunodeficiency virus ( hiv ) ) . issues relatin...
background : research has shown that there is a direct correlation between the loud hard - core music played on public transportation and the proliferation of sexual activities on these said transportations.aim:to determine the extent to which dancehall music / genre impacts adolescent behavior.materials and method : ...
the global incidence of diabetes mellitus ( dm ) has increased alarmingly in the past ten years , becoming one of the most common chronic diseases . it is estimated that this disorder will affect 552 million people by 2030 ( http://www.idf.org/media-events/press-releases/2011/diabetes-atlas-5th-edition ) . changing...
islet -cell replacement and regeneration are two promising approaches for the treatment of type 1 diabetes mellitus . indeed , the success of islet transplantation in normalizing blood glucose in diabetic patients has provided the proof of principle that cell replacement can be employed as a safe and efficacious trea...
cytologic examination of cerebrospinal fluid ( csf ) is routinely performed during the management of patients with malignancies that frequently have leptomeningeal spread , including patients with acute lymphoid leukemias ( all ) and medulloblastomas . cytology laboratories in large centers treating cancer patients o...
background : neoplastic meningitis ( nm ) is a condition characterized by leptomeningeal involvement by metastatic carcinoma . detection of exfoliated malignant cells in cerebrospinal fluid ( csf ) due to meningeal metastasis is frequently associated with diverse neurologic presentations.materials and methods : in th...
among the lipid nanoparticles , liposomes are widely studied as drug delivery vehicles . liposomes protect the encapsulated drugs from being metabolized during the circulation prior to reaching the target . the us food and drug administration has approved liposome - based formulations for the treatment of...
liposomes are representative lipid nanoparticles widely used for delivering anticancer drugs , dna fragments , or sirna to cancer cells . upon targeting , various internal and external triggers have been used to increase the rate for contents release from the liposomes . among the internal triggers , decr...
interstitial lung diseases ( ild ) are a heterogeneous group of diffuse parenchyma disorders characterized by different grades of fibrosis and inflammation . despite varying pathogenesis , they are grouped together because of their similar clinical presentation , chest radiographic appearance , histology , and physio...
interstitial lung disease ( ild ) and lung fibrosis are characterized by different grades of fibrosis and inflammation . persistent low - grade inflammation is believed to play a major pathogenic role , leading to an imbalance of cytokines , growth factors , and tissue proteinases . recruited monocytes and macrophage...
since many decades , bioactive heterocyclic compounds are one of the main topics of interest for the medicinal chemists as it displays a number of pharmacological activities . nitrogen , sulphur , and oxygen containing five- and six - membered heterocyclic compounds have occupied enormous significance in the field of...
a simple and efficient protocol is developed for the synthesis of 2-substituted-4,6-diarylpyrimidines from one - pot three - component reaction of 4-hydroxy-3,5-dinitro substituted chalcones , s - benzylthiouronium chloride ( sbt ) , and heterocyclic secondary amines ( morpholine / pyrrolidine / piperidine ) in the pre...
the conventional oral examination ( coe ) or viva voce is an important format of assessment that allows probing of breadth and depth of the knowledge . currently , this method is an integral part of formative and summative examinations in various medical universities in india . coe is criticized for being too subje...
objectives : the study aims to understand the process and factors influencing the implementation of structured oral examination ( soe ) for undergraduate medical students ; in comparison with conventional oral examination ( coe ) in pharmacology.methods:in a randomized , parallel group study , 123 students of pharmacol...
perivascular epithelioid cell tumor ( pecoma ) is a family of related mesenchymal neoplasms that include angiomyolipoma , lymphangiomyomatosis and clear cell ' sugar ' tumor of the lung , and a group of rare , morphologically and immunophenotypically similar lesions arising at a variety of visceral and soft tissue site...
a 7-year - old boy presented with hematochezia and abdominal pain . a 3.7-cm - sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy . the patient underwent surgical resection . pathological examination revealed a low - grade perivascular epithelioid cell tumor ( pecoma...
menarche is a vital maturational event of puberty in female adolescents . unlike other pubertal changes that are gradual and continuous , it is highly correlated with other pubertal characteristics and is , therefore , preferred as a benchmark for sexual maturation . the timing of menarche is an important determina...
menarche is an important milestone in the development of female adolescents . the study assessed the age at menarche using recall , its seasonality , and association with marital and nutritional status ( using midupper arm circumference [ muac ] ) among 3,923 female adolescents aged 1219 years in a rural area of bang...
the main purpose of antiretroviral therapy ( art ) is to improve the prognosis of patients infected with human immunodeficiency virus ( hiv ) by decreasing the incidence of opportunistic infection and subsequent hospitalization and mortality.1 however , several studies have suggested that highly active antiretroviral t...
backgroundderangement in fibrinolytic markers can result in thrombosis and cardiovascular problems . antiretroviral therapy ( art ) has been reported to affect the levels of these markers . it is unclear how long a patient can be exposed to art before the effect of the drugs on the fibrinolytic markers becomes noti...
several mechanisms have been proposed to explain the changes in balance during aging . since aging affects almost all physiological processes , reduction in postural stability can be explained by various factors , such as a loss of receptor cells in the vestibular organ , impaired sensory perception , a decline in musc...
as life expectancy continues to rise , in the future there will be an increasing number of older people prone to falling . accordingly , there is an urgent need for comprehensive testing of older individuals to collect data and to identify possible risk factors for falling . here we use a low - cost force platform ...
staphylococcus aureus , a gram - positive bacterium , is a commensal organism known to cause a wide range of hospital- and community - acquired infections . it is also recognized for immune evasion mechanisms and its ability to develop multi - antibiotic resistance . the burden of staphylococcal disease has increas...
staphylococcus aureus ( sa ) is a major community - acquired pathogen . the emergence of drug - resistant strains like , methicillin - resistant sa ( mrsa ) , poses stiff challenges to therapeutic intervention . passive immune - therapy with specific antibodies is being actively examined to treat fulminant infectio...
among the group - iii nitrides , wurtzite inn ( w - inn ) is a very promising semiconductor material of application in high - frequency / high - speed / high - power heterojunction field - effect transistors ( hfets ) [ 1 - 4 ] , due to its superior electron transport properties , small effective mass , and high mobili...
x - ray photoelectron spectroscopy has been used to measure the valence band offset ( vbo ) of the w - inn / h - bn heterojunction . we find that it is a type - ii heterojunction with the vbo being 0.30 0.09 ev and the corresponding conduction band offset ( cbo ) being 4.99 0.09 ev . the accurate determination of...
gait recovery is a major objective in the rehabilitation program for individuals with poststroke hemiparesis1 . treadmill training2 and treadmill training with harness support3,4,5 have been reported to be effective methods for retraining walking . hollands et al . reported that repetitive task - specific...
[ purpose ] the goal of this study was to investigate the efficacy of stepping - in - place training using a foot lifting assist device on the walking gait of chronic hemiparetic stroke patients . [ subjects ] seven patients with chronic hemiplegic stroke ( age 80.94.9 years ) who were attending a local adult ...
computational methodologies utilized for in silico high throughput screening ( hts ) are a critical component of drug discovery approaches . within the available in silico hts approaches , methodologies that combine ligand- and structure - based screening procedures find the widest application . the challenge i...
two factors contribute to the inefficiency associated with screening pharmaceutical library collections as a means of identifying new drugs : [ 1 ] the limited success of virtual screening ( vs ) methods in identifying new scaffolds ; [ 2 ] the limited accuracy of computational methods in predicting off - tar...
lupus erythematosus is a chronic , autoimmune disease resulting from an interaction of genetic , environmental , and hormonal factors and characterized by a spectrum of clinical forms with a variable evaluation from a localized cutaneous form to life - threatening systemic form . specific skin lesions of cutaneous lu...
the complement system is of great importance in systemic lupus erythematosus . complete genetically determined deficiencies are with few exceptions reported for the various complement proteins , and most of the deficiency states are rare . deficiencies of the factors in the classical pathway are also associated with ...
odor information is known to be of vital importance for most animals , and especially for insects . to achieve optimal fitness insects need to survive and reproduce in an optimal way . odors are known to play vital roles as cues for both these functions . to survive , optimally an insect needs to eat ( in most case...
drosophila melanogaster is today one of the three foremost models in olfactory research , paralleled only by the mouse and the nematode . in the last years , immense progress has been achieved by combining neurogenetic tools with neurophysiology , anatomy , chemistry , and behavioral assays . one of the most import...
staphylococcus aureus is one of the most common nosocomial pathogens which can cause a broad spectrum of infections , ranging from mild skin infections to severe abscesses , sepsis , endocarditis , osteomyelitis , urinary tract infections ( uti ) , and fatal necrotizing pneumonia ( 1 ) . staphylococcus aureus strains...
background : methicillin - resistant staphylococcus aureus ( mrsa ) is one of the most common nosocomial pathogens which can cause a broad spectrum of infections.objectives:the current study aimed to describe the frequency and antibiotic susceptibility patterns of clonal groups of gentamicin - resistant strains of mrsa...
stroke is a major cause of acquired disability and the secondleading cause of death in the world.1 , 2 the primary causes of stroke are unclear3 ; however , family studies indicate that genetic factors may be involved.4 , 5 a previous study demonstrated that 70% to 85% of strokes are ischemic , with the percentage vary...
backgroundischemic stroke is a major cause of death and disability in the world . a major ischemic stroke subtype , largevessel ischemic stroke ( large artery atherosclerosis ; laa ) , has been shown to have some genetic components in individuals of european ancestry . however , it is not clear whether the genetic pr...
with the increasing utility of invasive procedures in inpatient settings , nosocomial infections are encountered with more prevalence among the hospitalized population . hospital-/noncommunity acquired infections ( hai ) not only lengthen the duration of hospital stay with increased demand for additional health care ...
aim . to demonstrate the prevalence of isolated organisms in urinary / respiratory tract infections and their antibiotic susceptibilities in a tertiary care center . methods and material . between january 2008 and january 2010 , patients referring to the clinic of cardiology or those admitted to the cardiac wards were ...
coarctation of the aorta refers to a congenital narrowing of the aortic lumen and occurs in approximately 3.2 of 10,000 live births . the overall incidence has been reported to be between 5 and 8% of all congenital heart defects . aortic coarctation can be either pre - ductal ( 10% ) or post - ductal ( 90% ) , depe...
a 57-year - old female presenting with acute - onset paraplegia was referred for magnetic resonance imaging ( mri ) of cervico - dorsal spine . on mri , multiple tortuous dilated vessels were noted in the epidural space with long segment cord compression and imaging features of compressive myelopathy . associated s...
integration is the goal of many human service organizations , policymakers , theorists , and professionals . integrated health services hold the promise of improved efficiency , capacity , performance / quality , cost - effectiveness , and enhanced working environment with improved communication and cooperation [ 1 ,...
purpose . to explore the interactions between child and parents psychosocial factors and team integration variables that may explain improvements in physical dimensions of the peds ql quality of life of children with complex needs after 2 years . methods . in this 2-year study , parents were identified by the childre...
at the end of january 2003 , connecticut clinical laboratories were notified by mail that gpr isolates identified from csf or blood within 72 hours of culture inoculation must be reported to cdph epidemiology program . cdph asked laboratories to call the department immediately if the isolate was identified within 32 ...
connecticut established telephone - based gram - positive rod ( gpr ) reporting primarily to detect inhalational anthrax cases more quickly . from march to december 2003 , annualized incidence of blood isolates was 21.3/100,000 persons ; reports included 293 corynebacterium spp . , 193 bacillus spp . , 73 clostridium s...
animals : this study used client - owned 96 dogs that met the following criteria : suffering from spinal cord compression located between t3 and l3 vertebral articulation for duration of more than 6 hr and less than 4 days of neurologic dysfunction prior to mri and disk extrusion confirmed by mri and/or decompres...
the aim of this study was to evaluate the prognostic value of concurrent measurement of serum phosphorylated neurofilament heavy subunit ( pnf - h ) concentration and intramedullary t2w hyperintensity in paraplegic to paraplegic dogs . our hypothesis was that concurrent measurement of these would provide a more...
the metabolic syndrome ( ms ) is defined as a cluster of metabolic alterations , which includes the following diagnostic criteria : hypertension , diabetes , insulin resistance , dyslipidemia , and obesity . obesity , as component of ms , is considered a public health problem because of its magnitude and importance ....
the aim of this study was to evaluate the association between estrogen removal , antioxidant enzymes , and oxidative stress generated by obesity in a ms female rat model . thirty two female wistar rats were divided into 4 groups : control ( c ) , ms , ms ovariectomized ( ovx ) , and ms ovx plus estradiol ( e2 ) . m...
cryoglobulins are special serum immunoglobulin 's that usually precipitate at a temperature between 0c and 4c and dissolve when re - warmed to 37c . this in vitro phenomenon can be observed in a wide spectrum of infectious diseases , autoimmune disorders and with hematological malignancies . both type i and type ii...
cryoglobulinemias rarely been reported from india even though associated conditions such as hepatitis c infection , rheumatoid arthritis and plasma cell dyscrasias , etc . , are common occurrences . in many regions of the country , temperatures in winter can be conducive to the precipitation of cryoglobulins , yet ...
the organophosphate poisons ( opps ) , i.e. , herbicides and pesticides , are chemical compounds that are hazardous to environment ( 1 ) . increased population followed by increased demands for food , especially agricultural products , has pushed farmers to increase their products , and this has led to the greater us...
introductionmalathion is one of organophosphate poisons ( opps ) that inhibit cholinesterase activity and induce oxidative stress in target organs , such as the reproductive system . the aim of this study was to assess the effects of malathion on serum and erythrocyte cholinesterase activity in male rats and also to ...
the incidence of heterotopic ossification ( ho ) after primary hip arthroplasty varies between 8% and 90% in literature . the reason why heterotopic ossification develops is unknown , but it has been assumed that the inflammatory reaction due to the surgical trauma is the major driving force . the fact that the inc...
as cytokines are involved in wound healing and other inflammatory processes , it could be valuable to measure their levels at the operative site . this study was conducted to investigate whether different cytokines are measurable in drainage fluid and , when measurable , whether we can find a difference in cytokine l...
the early onset of sexual activity has been linked to risky health behaviors such as having a greater number of sexual partners over time and substance abuse.13 sexual activity for any teenage girl is risky due to multiple factors such as elevated risk of sexually transmitted infections ( sti ) and unwanted pregnancy ....
purpose : early onset of sexual activity has been linked to later substance abuse . our study aimed to further describe the associations between latina mothers and daughters early sexual activity and adult substance abuse.methods:a survey was conducted with 92 latina mother daughter dyads whose members never experi...
video - assisted thoracoscopic ( vats ) lobectomy has gradually gained popularity , and been accepted as an alternative procedure to thoracotomy for resectable lung cancer by national comprehensive cancer network ( nccn ) since 2013 . interest has developed on whether vats preserves better immune status and benefits ...
background : regulatory t - cells ( treg ) play key roles in suppressing cell - mediated immunity in cancer patients . little is known about perioperative treg fluctuations in nonsmall cell lung cancer ( nsclc ) . video - assisted thoracoscopic ( vats ) lobectomy , as a minimal invasive procedure for treating nsclc ,...
over the last 60 years , work performed on animal models , chiefly mouse , rat , and avian , and on human samples , has revealed and explored the capacity of adult stem cells - also called somatic stem cells to self - renew and to differentiate into unipotent progeny within their residing tissue , generally for the pu...
abstractaging is associated with both muscle weakness and a loss of muscle mass , contributing towards overall frailty in the elderly . aging skeletal muscle is also characterised by a decreasing efficiency in repair and regeneration , together with a decline in the number of adult stem cells . commensurate with th...
after arrival , rats were maintained on a constant 12-h light/12-h dark cycle with free access to water and ad libitum fed with a standard chow diet and allowed to acclimate for at least a week . all procedures were approved by the institutional animal care and use committee ( iacuc ) of the university of pittsburgh ...
objectiveincreased activity of the innate immune system has been implicated in the pathogenesis of the dyslipidemia and insulin resistance associated with obesity and type 2 diabetes . in this study , we addressed the potential role of kupffer cells ( liver - specific macrophages , kcs ) in these metabolic abnormalit...
although surgery is curative for localized disease , up to 30% of patients with rcc present with metastatic disease at the time of diagnosis , and more than 25% of patients with locally advanced rcc develop distant metastasis despite curative resection . since rcc is highly resistant to chemotherapy , high dose inter...
purposewe assessed the efficacy and safety of the tyrosine kinase inhibitor sunitinib in korean patients with metastatic renal cell carcinoma ( mrcc).materials and methodsbetween september 2007 and december 2009 , all twenty - one patients who had mrcc with a clear - cell component were retrospectively reviewed . sun...
in this issue of critical care , cuthbertson and colleagues report the views of 141 intensive care and infection control specialists from four countries on the potential utility , risks and research opportunities of selective digestive decontamination ( sdd ) . using structured interviews , a delphi process , and a t...
barriers to the use of selective digestive decontamination include concerns about emergence of resistant organisms , over - estimation of current performance in preventing ventilator - associated pneumonia ( vap ) , alternative methods of preventing vap , and misunderstanding of mechanisms of action . a definitive cl...
pertussis , an acute infectious illness of the respiratory tract remains endemic in developed nations despite high vaccination coverage [ 7 , 8 , 16 ] . while the early use of whole - cell vaccine was highly effective in reducing the incidence of reported pertussis in the united states in the 1970s , there has been a...
despite high vaccination coverage , over the last fifteen years there has been a worldwide resurgence of b. pertussis infection . while classical pertussis in the prevaccine era was primarily a childhood disease , today with widespread vaccination , there has been a shift in the incidence of disease to adolescents an...
although in most cases post - lp headaches are not severe and have a benign course , they can also be a manifestation of a potentially life - threatening complication such as subdural hematoma ( sdh ) . we describe a patient in whom a massive sdh developed after lp and cerebrospinal fluid ( csf ) drainage , which wer...
backgroundheadache is a common complication of lumbar puncture ( lp ) . although in most cases post - lp headaches are not severe and have a benign course , they can also be a manifestation of a potentially life - threatening complication such as subdural hematoma ( sdh).case reportwe describe a patient in whom a mas...
anemia is a disease that can co - exist with depression , other mental disorders , or somatic diseases . anemia can imitate symptoms of depression , while depression symptoms can mask concurring symptoms of anemia . i am presenting a case of a 48-year - old woman with addison biermer anemia , with co - existing mo...
backgroundanemia is a disease that can co - exist with depression , other mental disorders , or somatic diseases . anemia can imitate symptoms of depression , while depression symptoms can mask concurring symptoms of anemia.case presentationi am presenting a case of a 48-year - old woman with addison biermer anemia ...
plasmodium falciparum is responsible for the main disease burden afflicting primarily sub - saharan africa . in areas with stable malaria transmission , due to protracted exposure to infectious bites , partial protective immunity to clinical malaria there is however one exception to this general rule : pregnancy - as...
pregnancy - associated malaria is a major global health concern . to assess the plasmodium falciparum burden in pregnancy we conducted a cross - sectional study at mulago hospital in kampala , uganda . malaria prevalence by each of three measures peripheral smear , placental smear , and placental histology was 9% ( ...
diabhycar was a 6-year clinical trial conducted in men and women with type 2 diabetes selected on the basis of persistent microalbuminuria ( uae , 20200 mg / l ) or macroalbuminuria ( uae the trial tested whether a low dose of ramipril , an ace inhibitor able to reduce uae , also would reduce cardiovascular and/or re...
objectiveplasma copeptin , a surrogate for vasopressin , was associated with albuminuria in population - based studies . these associations are consistent with the effect of vasopressin on albuminuria observed in humans and rodents . the objective of this study was to determine whether plasma copeptin is an indepen...
this seeming paradox is rooted in the fact that there is intense skeletal growth and development during childhood and adolescence , and much more bone is formed than lost . later in life , the loss of bone tissue exceeds the rate of bone replacement . it , therefore , follows that lifelong bone health is dependent on...
during normal childhood and adolescence , the skeleton undergoes tremendous change . utilizing the processes of modeling and remodeling , the skeleton acquires its adult configuration and ultimately achieves peak bone mass . optimization of peak bone mass requires the proper interaction of environmental , dietary , h...
edentulism is regarded as a poor health outcome since it may compromise an individual 's quality of life . majority of these edentulous patients are treated in teaching institutes in which a large number of complete dentures are delivered by final year students and interns guided by staff members . a successful tre...
purpose : the purpose was to assess the outcome of improved staff supervision on the efficiency and quality of complete dentures delivered by clinical students.materials and methods : the audit was performed in two parts . in the first cycle , retrospective analysis for complete dentures delivered by clinical student...
psychologists have systematically studied the issue of transfer of training for over a century . the early work of american psychologist edward thorndike ( 18741949 ) set the stage for much of the research that followed . thorndike , a professor at columbia university s teachers college , conducted a series of influe...
editor s note : few topics in the world of neuroscience evoke as much debate as the effectiveness of cognitive training . do you misplace your keys regularly ? forget appointments ? have trouble remembering names ? no worries . a host of companies promise to train your brain with games designed to stave off m...
expansion of antibody scaffold diversity has the potential to expand the neutralizing capacity of the immune system and to generate enhanced therapeutics and probes . systematic exploration of scaffold diversity could be facilitated with a modular and chemical scaffold for assembling proteins , such as dna ...
myoinositol ( mi ) and d - chiro inositol ( dci ) are isomeric forms of inositol that were found to have insulin - like properties , acting as second messengers in the insulin intracellular pathway ; both of these molecules are involved in the increasing insulin sensitivity of different tissues to improve metabolic and...
myoinositol and d - chiro inositol , which are inositol isomers , have been shown to possess insulin - mimetic properties and to improve insulin resistance , especially in women with polycystic ovary syndrome . however , it has not been determined if this relationship exists also in children . based on these previo...
lipoid proteinosis , also known as hyalinosis cutis et mucosae ( omim 247100 ) , was first described by urbach and wiethe in 1929 . since then , over 250 cases of this autosomal recessive disorder have been described . it is characterized by the deposition of an amorphous hyaline substance ( glycoprotein ) in the muc...
lipoid proteinosis is a rare hereditary metabolic disorder transmitted as an autosomal recessive trait . it is characterized by the deposition of an amorphous hyaline - like material ( glycoprotein ) in the mucous membranes , skin and various internal organs . cryosurgery ( n2o ) was applied to remove and reshape t...
worldwide , it is the second leading cause of death and the leading cause of adult disability . so far , acute stroke therapies aim at recanalizing the occluded brain vessels by means of pharmacologic thrombolysis or thrombectomy . decades of research on ( neuro)protective drugs have established several promising c...
ceramides induce important intracellular signaling pathways , modulating proliferation , migration , apoptosis , and inflammation . however , the relevance of the ceramide metabolism in the reconvalescence phase after stroke is unclear . besides its well - known property as a selective serotonin reuptake inhibitor ...
a 43-year - old woman underwent neck sonography as part of a routine medical checkup . six years earlier she had received a renal transplant , and the kidney involved had been functioning well up to the time of the checkup . neck ultrasonography revealed a 2.91.4-cm hypoechoic mass at the inferoposterior aspect of th...
we report two cases of paratracheal air cyst discovered incidentally at neck ultrasonography and confirmed at ct . the cysts were located at the inferoposterior aspect of the right lobe of the thyroid . ultrasonography revealed an ill - defined hypoechoic mass containing hyperechoic foci which mimicked calcificatio...
in western societies , two out of three people have low - back pain at some point during their life , and in one out of five of these cases , the pain persists for more than 4 weeks . cases where symptoms persist for more than 712 weeks are diagnosed as chronic low - back pain . prominent structures that are the so...
study design : retrospective cohort study.purpose:facet joints are considered a common source of chronic low - back pain . to determine whether pathogens related to the facet joint arthritis have any effect on treatment failure.materials and methods : facet joint injection was applied to 94 patients treated at our ho...
hashimoto 's thyroiditis is the combination of autoimmune thyroiditis and goiter ; a positive test result for thyroid auto antibodies ( antithyroglobulin and antiperoxidase ) will confirm the diagnosis.current and previous drug use check for history of thyroid surgery or head and neck irradiation and radioactive iodin...
background : hypothyroidism is the most common endocrine disease that was seen in the clinical practice especially for family physicians.methods:this review article covered the important practical clinical issues for managing overt hypothyroidism , subclinical hypothyroidism and hypothyroidism during pregnancy.conclusi...
fifty - seven consecutive patients with pathologically - proven hippocampal sclerosis who underwent anterior temporal lobectomy between october 1994 and april 1997 for the treatment of intractable medial temporal lobe epilepsy and were followed - up for over 24 months were included in this study . thirty - eight were...
objectiveatrophy and a high t2 signal of the hippocampus are known to be the principal mr imaging findings of hippocampal sclerosis . the purpose of this study was to determine whether or not individual mri findings correlate with surgical outcome in patients with this condition.materials and methodspreoperative mr i...
post - operative nausea and vomiting ( ponv ) is not only discomforting , but also may result in serious aftermaths such as dehydration , electrolyte disturbances , aspiration , surgical sutures dehiscence , esophageal rupture , subcutaneous emphysema and pneumothorax that in turn would delay patient s recovery and hos...
background : some studies reported that ginger was effective in prevention or treatment of post - surgical nausea and vomiting ; however , there are controversies . in addition , no study compared the effects of ginger on nausea and vomiting after open and laparoscopic nephrectomies.objectives:the current study aimed t...
entamoeba histolytica , the causative agent of human amoebiasis provokes the second worldwide highest rates of morbidity and mortality due to protozoa . e. histolytica trophozoites obtain host nutrients from a very active uptake and efficient engulfment of bacteria , red blood cells ( rbc ) , and cell debris , which ...
ehadh112 is an entamoeba histolytica bro1 domain - containing protein , structurally related to mammalian alix and yeast bro1 , both involved in the endosomal sorting complexes required for transport ( escrt)-mediated multivesicular bodies ( mvb ) biogenesis . here , we investigated an alternative role for ehadh112 in ...
root canal treatment is a rather new branch of endodontic dentistry in recent years through , which chemical and mechanical remedies are used to limit pulpal and peri - apical diseases . this biologically approved technique has helped peri - apical tissues in the process of healing significantly . the above techniq...
background : endodontic procedures such as root canal treatment would be at the risk of failure like other medical interventions due to any unsuitable conditions . this has a causative effect in making the procedure more complicated to resulting in weak prognosis finally . technical errors such as ledge , perforati...
synovial cell sarcoma ( scs ) of the kidney is a rare tumor entity first described in 1999 and published in 2000 by argani et al . [ 1 , 2 ] . to date , no more than 50 cases have been described in the literature . differential diagnosis mainly includes renal sarcomatoid carcinoma , metastatic sarcoma , solitary fi...
synovial cell sarcoma ( scs ) of the kidney is a rare tumor entity with a poor prognosis . morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney . therefore , the diagnosis of primary renal scs not only requires the exclusion of similar tumor types , but also...
venom immunotherapy ( vit ) is an extremely effective form of treatment for individuals at risk of insect sting systemic reactions , i.e. flying hymenoptera , an order of insects comprising honeybees , yellow jackets , hornets , and wasps . vit reduces the risk of a subsequent systemic sting reaction to as low as 5% ...
abstractobjectives . to describe ( i ) the clinical characteristics of workers , exposed to hymenoptera stings , with an ascertained diagnosis of hymenoptera venom allergy ( hva ) , ( ii ) the specific role of occupational exposure , ( iii ) the effect of venom immunotherapy ( vit ) in reducing the severity of allergic...
peripheral t - cell lymphomas ( ptcl ) are a rare and heterogeneous group of non - hodgkin s lymphomas ( nhl ) deriving from mature , post - thymic t- and natural killer ( nk- ) cells . ptcl count for approximately 10% of all nhl in europe and north america,13 but present with a higher incidence in east asia and the ...
peripheral t - cell lymphomas ( ptcl ) represent a heterogeneous group of rare malignancies that with the exception of anaplastic lymphoma kinase expressing anaplastic large cell lymphoma , share a poor outcome after standard ( eg , anthracycline - based ) chemotherapy . most patients are either refractory to initial...
although the results of adult and embryonic stem cell therapy for the infracted myocardium have yielded promising results for the enhanced regeneration of myocardial tissue leading to improved ventricular function [ 13 ] , the effectiveness of stem cell therapy is often blurred from the non - survival of the stem cells...
abstractto study the efficiency of maintaining the reduced tissue environment via pre - treatment with natural antioxidant resveratrol in stem cell therapy , we pre - treated male sprague - dawley rats with resveratrol ( 2.5 mg / kg / day gavaged for 2 weeks ) . after occlusion of the left anterior descending coronar...
immunoglobulin light - chain amyloidosis ( al ) is a rare systemic disease characterized by progressive tissue and organ extracellular fibrillar deposition . kidney spontaneous rupture is not a recognized complication in amyloidosis or autologous stem cell transplantation ( asct ) . we report the singular case of a...
kidney spontaneous rupture is not a recognized complication neither for amyloidosis nor of autologous stem cell transplantation ( asct ) . a 46-year - old white woman , affected by nephrotic syndrome , was diagnosed as al amyloidosis by renal biopsy . we report the singular case of a bilateral spontaneous kidney ru...
trichotillomania ( ttm ) is a type of impulse control disorder , characterized by recurrent pulling of hair , which leads to pleasure and relief of tension . prevalence rates of this condition range between 1% and 13.3% , with initial mean age of onset between 10 years and 13 years and a notable peak at 12 - 13 . t...
trichotillomania ( ttm ) is a type of impulse control disorder , characterized by recurrent pulling of hair . the etiology of ttm is complex , but a genetic contribution to this condition was advocated based on a limited number of reports on familial ttm . we report a 13-year - old male with history of focal hair l...
the cystic fibrosis transmembrane conductance regulator ( cftr ) is a chloride channel in the apical membrane of epithelial cells 1 . mutations in cftr result in impaired chloride conductance across the plasma membrane and are the basis of the genetic disease cystic fibrosis 2 . almost 90% of patients contain at le...
chloride channel gating and trafficking of the cystic fibrosis transmembrane conductance regulator ( cftr ) are regulated by phosphorylation . intrinsically disordered segments of the protein are responsible for phosphoregulation , particularly the regulatory ( r ) region that is a target for several kinases and phos...
those aged 65 and older represented 35.9 million or 12.3% of the us population in 2003 , and this number will reach 19% by the year 2030 . the great majority of deaths ( 8085% ) occur in this population , and most die from chronic conditions such as heart failure , cancer , obstructive pulmonary disease , diabetes , al...
purpose . the purpose of this study was to identify variables that influenced completion of advanced directives in the context of adaptation from national data in older adults . knowledge gained from this study would help us identify factors that might influence end of life discussions and shed light on strategies ...
in the last ten years , in our country , there has been an increase in the consumption of raw fish due to the introduction of new eating habits from countries outside europe ( sushi , sashimi , herring , pickled anchovies , etc . ) , increasing the risk of contracting parasitic diseases , in particular the anisakiasis ...
one of the parasite diseases associated with the consumption of raw fish that occurs with some frequency is the anisakiasis , a human disease caused by the accidental ingestion of larval nematodes of the genus anisakis , family anisakidae . at the national reference centre for anisakiasis ( c.re.n.a . ) from october 20...
telepathology refers to the remote practice of pathology via transmitting digital images . since the introduction of telepathology almost 46 years ago wsi ( virtual microscopy ) refers to the digitization of glass slides by scanners to generate high - resolution digital slides . operationally , it is often easier t...
background : telepathology is increasingly being employed to support diagnostic consultation services . prior publications have addressed technology aspects for telepathology , whereas this paper will address the clinical telepathology experience of kingmed diagnostics , the largest independent pathology medical labo...
arthrogryposis multiplex congenita ( amc ) is a multiple joint condition which affects both lower and upper extremities and thus affects ambulation . the objective of this study is to identify the most critical residual deformity that diminishes the ambulatory status . the mean age at first surgery was 4.1 years ( ...
background : arthrogryposis multiplex congenita ( amc ) is a multiple joint condition which affects both lower and upper extremities and thus affects ambulation . multiple surgeries are needed to correct limb deformity in order to promote walking . the objective of this study is to identify the most critical residu...
we used 2 g of total rna from human umbilical vein ecs ( huvecs ) cultured under normoxic or hypoxic conditions for 24 h and subjected to rna - seq analysis ( n = 3 ) . after extracting the total rna from the samples , the left rna was fragmented into short fragments , then the first strand complementary deoxyribonu...
backgroundlong noncoding ribonucleic acids ( lncrnas ) are a subclass of regulatory noncoding ribonucleic acids for which expression and function in human endothelial cells and angiogenic processes is not well studied.objectivesthe authors discovered hypoxia - sensitive human lncrnas via next - generation ribonucleic a...
actin - rich membrane protrusions such as filopodia and lamellipodia can guide the convergence of cells during the formation of complex signaling interfaces in vivo , for example , during synaptogenesis in the nervous system or the merging of epithelial cell sheets during development or wound healing ( mattila and lapp...
metazoan cells rapidly exchange signals at tight cell cell interfaces , including synapses and gap junctions . advances in imaging recently exposed a third mode of intercellular cross - talk mediated by thin , actin - containing membrane extensions broadly known as membrane or tunneling nanotubes . an explosio...
as the aids ( acquired immunodeficiency syndrome ) epidemic enters its fourth decade , hiv transmission in most parts of the world shows no signs of abating despite great progress being made in tackling the epidemic worldwide . it still continues to grow in countries of all incomes with a greater impact on the more vul...
candida is a common opportunistic pathogen during the course of human immunodeficiency virus ( hiv ) disease progression . changes in the clinical severity of candidiasis and the candida species prevalence profile may be a reflection of immunological changes in hiv positive patients . the aim of this study was to d...
we studied 20 serum samples from survivors of confirmed hantavirus infection , 11 from chilean patients and 9 from patients in the southwestern united states . samples were collected from 8 months to 11 years after the patient was hospitalized with hcps . the neutralizing titer was measured for each sample against ...
we evaluated titers of homotypic and heterotypic neutralizing antibodies ( nabs ) to andes and sin nombre hantaviruses in plasma samples from 20 patients from chile and the united states . all but 1 patient had high titers of nab . none of the plasma samples showed high titers against the heterologous virus .
cases of linear peritoneal calcification have been reported in literature , though they occur rarely . in encapsulating peritoneal sclerosis ( eps ) a peritoneal membrane damage develops an inflammatory cascade that results in sclerosis and eventually calcification . eps has been can be either primary or secondary ...
the peritoneum is the largest serous membrane of the body and can be exposed to several injuries that may cause abnormal findings on imaging exams . linear peritoneal calcification is remarkably rare , usually secondary to long duration peritoneal dialysis.we report an uncommon case of extensive peritoneal calcificat...
we hypothesize that the type of disaster , and thus the investigation of its unique characteristics , are important for a better understanding of perceived post- and peritraumatic stress levels in survivors . additionally personal and situational characteristics are also likely to play a role in how survivors think a...
backgroundexamination of existing research on posttraumatic adjustment after disasters suggests that survivors posttraumatic stress levels might be better understood by investigating the influence of the characteristics of the event experienced on how people thought and felt , during the event as well as afterwards.obj...
scientific studies play an important role among them ( 1 ) . during the past two decades , iran has enjoyed considerable expansion of trained individuals in the fields of medicine ( 2 ) for being a developed and industrial country . therefore , the policy of iranian governors changed in the recent years to provide ...
context : we performed a bibliometric search to evaluate the number of papers published in the field of nephrology and urology by iranian researchers in the past two decades.evidence acquisition : we did an online search in abstract / title part of articles with 129 keywords such as kidney , renal , hemodialysis , tran...
spinal canal stenosis is a syndrome of various etiology , whose morphological manifestation is narrowing of the spinal canal , intervertebral foramina , and lateral recesses . it is the most common cause for surgical treatment in patients over 65 years of age . in the surgical treatment for lumbar stenosis , variou...
backgroundthe purpose of this study was to evaluate lumbar spine - related functional disability in individuals 10 years after lumbar decompression and lumbar decompression with posterior lumbar interbody fusion ( plif ) with corundum implants surgery for degenerative stenosis and to compare the long - term outcome of ...
after surgical removal the catecholamines elaborated by the tumor also take time to be washed out of the circulation thus the blood pressure will need careful monitoring . conventional alpha blockage first and beta blockage later was the algorithm followed but choice of agent was also discussed with nesthethesiologis...
pheochromocytomas or paragangliomas are neroendocrine tumors elaborating catecholamines . they may not present always in a classic manner and a high degree of suspicion is important in diagnosing them early . they can grow large enough to impinge on the great vessels and yet symptoms may not indicate the severity u...
house - dust mites ( hdm ) ( dermatophagoides pteronissinus ) allergens are among the most potent stimuli of asthma attacks [ 1 , 2 ] . hdm excretions contain a plethora of biologically active compounds , which have allergenic potential that prompts ige response in sensitized subjects . the same hdm compounds also ...
background . bronchial smooth muscle cells ( bsmc ) are a major source of proinflammatory and proangiogenic cytokines and chemokines , including vegf and cxc - chemokines . cxc - chemokines act primarily on neutrophils , mediating their recruitment to and activation at the site of inflammation . in humans , house -...
cladophora glomerata ( cg ) ktzing has been naturally grown in the north of thailand . local people have traditionally used this alga as an ingredient in several northern thai dishes and believed that it could serve as a medicinal plant for several diseases . previous in vivo studies have suggested that cg extract ...
cladophora glomerata extract ( cge ) has been shown to exhibit antigastric ulcer , anti - inflammatory , analgesic , hypotensive , and antioxidant activities . the present study investigated antidiabetic and renoprotective effects of cge in type 2 diabetes mellitus ( t2 dm ) rats . the rats were induced by high - f...
schwartz ( 1952 ) coined the term atrophia idiopathica mucosa oris to describe an oral fibrosing disease . in 1953 , joshi subsequently termed the condition oral submucous fibrosis ( osf ) . osf is an insidious chronic disease affecting any part of the oral cavity and may extend to pharynx and esophagus , and may b...
atrophia idiopathica mucosa oris is an oral fibrosing disease resulting in marked rigidity and an eventual inability to open the mouth or had limited mouth opening . patients with limited mouth opening are a common occurrence in prosthodontic practice . the majority of these patients can be treated with exercise an...
exposure to asbestos fibers increases the risk of disease and death for different causes , but its impact on health is not properly reflected in statistics on occupational disease and must be quantified in specific studies . there have been some local studies of this type1 and in relation to specific diseases in spai...
the objective of this article was to estimate the medical costs derived from malignant ard treatment in the spanish national health system ( nhs ) between 2004 and 2011 . estimation of direct healthcare costs was based on national primary data on the cost of specialized care for inpatients and outpatients treated at ...
acinetobacter baumannii is microbiologically characterized as a rod - shaped , aerobic , pleomorphic , and nonmotile gram - negative bacterium . a. baumannii can survive in natural environments such as soil and water for a prolonged period and mainly infect immunocompromised patients . this opportunistic organism i...
acinetobacter baumannii is a significant cause of severe hospital - acquired infections with a recent rise in multidrug - resistant infections involving traumatic wounds of military personnel . the interleukin-17 ( il-17 ) pathway is essential for neutrophil recruitment in response to a variety of pathogens , while t...
idiopathic pulmonary fibrosis ( ipf ) is a specific form of chronic , progressive , fibrosing interstitial pneumonia of unknown cause that occurs primarily in older adults . pulmonary hypertension ( ph ) describes a group of devastating diseases causing breathlessness , loss of exercise capacity , and death due to ri...
background : pulmonary hypertension ( ph ) frequently complicates the course of idiopathic pulmonary fibrosis ( ipf ) patients and is associated with significantly worse outcomes . the aim of the present study was to investigate the incidence of ph in ipf patients and evaluate the correlation between clinical paramet...
neoadjuvant chemotherapy ( nac ) treatment for women diagnosed with local - regional disease has been shown to reduce the tumor size of most breast tumors and decrease the incidence of positive nodes . the 5- and 9-year follow - up results from the national surgical adjuvant breast and bowel project b-18 indicate ove...
objectives : in this prospective pilot study , the feasibility of non - contrast dedicated breast computed tomography ( bct ) to determine primary tumor volume and monitor its changes during neoadjuvant chemotherapy ( nac ) treatment was investigated.materials and methods : eleven women who underwent nac were imaged wi...
glucose-6-phosphate dehydrogenase ( g6pd ) ( e.c.1.1.1.49 ) is the key regulatory enzyme in the hexosemonophosphate shunt that catalyzes the oxidation of glucose 6- phosphate to 6-phosphogluconolactone ( 1 , 2 ) . this first and rate - limiting step of shunt is associated with production of nicotinamide adenine dinuc...
backgroundg6pd deficiency is the most common enzymopathy of red blood cells . the clinical symptoms of favism are jaundice , hematuria and haemolytic anaemia that seem to affect liver and kidney in long term . thus we evaluate kidney and liver function of favism patients in an endemic area of the disease with a hig...
intravenous immunoglobulin [ ivig ] is used for treatment of a variety of autoimmune , rheumatologic , and immunodeficiency [ both primary and secondary ] disorders and can be life - saving in several of these conditions . although it has good safety profile , it can be rarely associated with serious adverse events ....
intravenous immunoglobulin [ ivig ] is useful for treating several clinical conditions and is largely considered safe , without major adverse events . here we report a case of acute st elevation myocardial infarction associated with high dose ivig administration in a previously healthy 69-year - old male patient of g...
age - related changes in skeletal muscle result in loss of muscle mass and weakness . this leads to a decrease in daily physical activity in older adults , and can result in poor health and a need for professional care . muscle loss and weakness cause serious health problems , such as decreased strength and a...
[ purpose ] to maintain an independent lifestyle , older adults should improve muscle strength and mass , or aerobic capacity . a new exercise pattern , called slow walking with turns , which incorporates turning as an extra load additional to walking . the purpose of this study was to measure oxygen consumption ...
clostridium difficile , a gram - positive and spore - forming anaerobic bacillus , is a leading cause of healthcare - associated diarrhoea in industrialized countries . transmission occurs primarily in healthcare facilities , where exposure to antibiotics and environmental contamination by c. difficile spores are co...
an aggregation of moxifloxacin - resistant clostridium difficile ribotype 231 ( rt231 ) isolates was first identified in the county of stockholm in 2008 , and by the end of 2015 isolates of rt231 had spread to 13 of 21 swedish counties . we investigated the epidemiology of c. difficile rt231 in sweden between 2006 a...
primary osteoarthritis ( oa ) is an idiopathic phenomenon , occurring in previously intact joints , with no apparent initiating factor such as joint injury or developmental abnormalities . it is characterized by the progressive failure of the extracellular cartilage matrix leading to articular cartilage destruction.1...
family , twin , adoption studies show osteoarthritis ( oa ) has a substantial genetic component . several studies have shown an association between oa and growth differentiation factor 5 ( gdf5 ) , some others have not . thus , the status of the oa - gdf5 association is uncertain . this meta - analysis was applie...
dengue viruses , single - stranded positive polarity ribonucleic acid ( rna ) viruses of the family flaviviridae , are the most common cause of arboviral disease in the world . dengue viruses have four serotypes , designated dengue types 1 - 4 ; and are transmitted mainly by bite of aedes aegypti mosquito and also by...
background : dengue viruses , single - stranded positive polarity ribonucleic acid ( rna ) viruses of the family flaviviridae , are the most common cause of arboviral disease in the world . we report a clinico - epidemiological study of the dengue fever outbreak of 2010 from a tertiary care hospital in delhi , north ...
schizophrenia is a chronic mental disorder that affects approximately 1% of the world population and is characterized by a relapsing course with significant burden for patients , families , and society.13 although many patients receiving chronic antipsychotic therapy can be considered clinically stable , a subgroup of ...
background : long - acting injectable antipsychotics may improve medication adherence , thereby improving overall treatment effectiveness . this study aimed to evaluate the effectiveness , safety , and tolerability of risperidone long - acting injection in schizophrenic patients switched from oral antipsychotic medic...
tobacco use is a leading public health problem all over the world with 82% of the world 's 1.1 billion smokers residing in low and middle income countries and where , in contrast to the declining consumption in high - income countries , tobacco consumption is on the rise . tobacco consumption has overall been a major...
aim : to assess the prevalence and correlates of current smoking , awareness of hazards , and quitting behavior among smokers 30 years and above.materials and methods : study design : cross - sectional ; setting : gokulpuri , a resettlement colony in east delhi , india ; sample size : 911 , persons aged 30 years and ab...
the objective of this study was to present the outcome of the internal limiting membrane ( ilm ) peeling flap technique for a treatment - nave , flat edge ( type ii ) , full - thickness macular hole ( mh ) . a 52-year - old man presented with complaints of decreased vision and seeing black spot . he was diagnosed t...
objectivethe objective of this study was to present the outcome of the internal limiting membrane ( ilm ) peeling flap technique for a treatment - nave , flat edge ( type ii ) , full - thickness macular hole ( mh).methodsa 52-year - old man presented with complaints of decreased vision and seeing black spot . he was ...
the conventional inorganic synthetic procedures usually demand long reaction time , high temperature , and toxic solvents . different from the traditional solvents , ionic liquids are potential green solvents with many advantages , such as negligible vapor pressure , low interface tension , supramolecular solvents , ...
zinc hydroxide fluoride ( zn(oh)f ) with novel flower - like morphology has been prepared via a microwave - assisted ionic liquid route . the flower - like zn(oh)f particle has six petals and every petal is composed of lots of acicular nano - structure . nanoporous zno is obtained by thermal decomposition of as - p...
tension pneumocephalus is infrequent and the limited number of cases reported all involve positive airway pressure ventilation after head trauma with an undiagnosed skull fracture . we present a rare case of violent pneumocephalus after head trauma not involving mask ventilation but based on pathological respiration ...
objectiveswe present a rare case of tension pneumocephalus ( tp ) after head trauma not involving mask ventilation but based on pathological respiration pattern , kussmaul breathing.tp is rare condition and exceptionally rare when positive airway pressure has not been applied . in this particular case , the vacuum an...
dental bonding materials form a bond between tooth structure and the restorative materials . this formed adhesive bond will provide protection of the tooth structure during restoration and will lengthen the restorations clinical lifetime.1 different classifications can be made including dentin bonding agents clinical a...
objectivesfirst to compare different dentin bonding agents shear bond strength to primary and permanent dentin . secondly to compare the fracture failure modes and making an attempt to develop a statistical model that could be helpful in predicting them.methodsextracted human primary and permanent molars were used as...
however , compared with open cholecystectomy , the incidence of bile duct injury appears to be increased , resulting in significant morbidity . bile duct injury during lc ranges from mild to severe with serious and disastrous consequences . it may lead to fistula formation or life - threatening biliary peritonitis ...
bilomas resulting as a complication of cholecystectomy are often due to a leak from an inadequately secured cystic duct stump , an accessory bile duct or a duct of luschka in the gallbladder fossa of the liver . occasionally , bilomas may have an unusual presentation . we describe here a rare case of biloma in the ...
anterior cruciate ligament ( acl ) injuries are one of the most common and devastating knee injuries associated with sport participation1 . surgical repair of complete rupture of the acl is recommended to prevent knee joint instability . while surgery corrects the structural defect , post - operative impairme...
[ purpose ] after an anterior cruciate ligament injury and subsequent reconstruction , quadriceps muscle weakness and disruption of proprioceptive function are common . the purpose of this study was to examine the effects of a 4 weeks preoperative exercise intervention on knee strength power and function post -...
all experimental procedures conform to the uk animals ( scientific procedures ) act 1986 and to ethical standards set out by the university of leeds ethical review committee . 1012 day old wistar rats ( n=89 ) of either sex were deeply anaesthetized with urethane ( 2 g / kg of body weight intraperitoneally ) . anim...
neuronal networks generating rhythmic activity as an emergent property are common throughout the nervous system . some are responsible for rhythmic behaviours , as is the case for the spinal cord locomotor networks ; however , for others the function is more subtle and usually involves information processing and/or t...
amyloids are large aggregates of misfolded proteins with a highly stable cross -structure , which are associated with a variety of degenerative illnesses such as alzheimer s , parkinson s , and huntington s diseases . proteins with different functionalities and native structures ranging from -helical and -she...
amyloid fibrils are large aggregates of misfolded proteins , which are often associated with various neurodegenerative diseases such as alzheimer s , parkinson s , huntington s , and vascular dementia . the amount of hydrogen sulfide ( h2s ) is known to be significantly reduced in the brain tissue of people...