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american visceral leishmaniasis ( avl ) is a serious public health problem in brazil and presents a new epidemiological profile associated with domestic environments and , in this context , lutzomyia ( lutzomyia ) longipalpis is important considering its capacity to adapt to a wide range of impacted habitats , in addit... | the aim of this study was to identify potential blood feeding sources of l. ( l. ) longipalpis specimens from populations in northeastern brazil , endemic areas of american visceral leishmaniasis ( avl ) and its correlation with the transmission of l. ( l. ) i. chagasi .
the elisa technique was applied using bird , d... |
a
curative therapy has not been established for pd , and a combination of drug therapy ,
surgical treatment , and physical therapy is recognized as the standard treatment1 , 2 . the estimated incidence of pd in japan is 50 per 100,000 in the overall population and 200
per 100,000 in the population aged 64 or olde... | [ purpose ] the aim of this study was to clarify the effects of guidance in home exercise
on physical function and the amount of activity in home care patients with parkinson s
disease ( pd ) . [ subjects and methods ] a 2-month home exercise intervention consisting of
self - administered exercise by patients ( s... |
oral lichen planus ( olp ) is a chronic inflammatory disease affecting 1 - 2% of general adult population .
andreasen s classical classification was modified by other authors who sub classified olp to reticular , atrophic , and erosive forms . in the erosive form
one theory is that in olp , autocytotoxic cd t - cel... | background : oral lichen planus is a chronic inflammatory disease with a poorly understood etiology . the role of angiogenesis in the development of different chronic inflammatory diseases is of great concern . vascular endothelial growth factor ( vegf ) is an important regulator of angiogenesis .
we aimed to evaluat... |
posttraumatic stress disorder ( ptsd ) is an anxiety disorder that can develop following exposure to traumatic life events .
central clinical features of ptsd include a persistent , heightened experience of alarm and distress , as well as a failure of extinction processes to diminish the emotional impact of traumatic... | endocannabinoids and their attending cannabinoid type 1 receptor ( cb1 ) have been implicated in animal models of posttraumatic stress disorder ( ptsd ) . however , their specific role has not been studied in people with ptsd .
herein , we present an in vivo imaging study using positron emission tomography ( pet ) an... |
wide disparities in health outcomes have been described for racial and ethnic minorities in the united states .
the institute of medicine , charged with examining disparate health outcomes , found that a large body of research supports inequities in health care as possible contributors to inequities in health .
tho... | the objective of this article is to determine whether racial / ethnic disparities exist in screening for group b streptococcus ( gbs ) colonization among pregnant women .
a retrospective cohort study of deliveries at a single institution was conducted .
the primary outcome was the availability of gbs culture data a... |
surveys on skin diseases of dogs demonstrate that neoplastic tumors of the skin are common [ 13 ] .
several studies report that in dogs the skin is the most commonly affected organ for both neoplastic and nonneoplastic tumors [ 47 ] . in one study ,
it has long been recognized among human populations that incidence... | this retrospective survey was undertaken between 2002 and 2007 on samples from dogs residing in grenada .
the objectives of the study were to identify the most common histologic types of canine cutaneous tumors , determine the relative frequency of each tumor type , and compare results to reports from other regions .... |
lower extremity amputation remains a definitive therapy for the management of ischemic disease that fails revascularization . despite recent advances in revascularization techniques and broadening of indications ,
each year 55,000 to 65,000 major lower extremity amputations are performed in the usa , making lower ext... | background : despite low peri - operative mortality after major lower extremity amputation , long - term mortality remains substantial .
metabolic syndrome is increasing in incidence and prevalence at an alarming rate in the usa.aim:this study was to determine whether metabolic syndrome predicts outcome after major l... |
. early detection of a supraspinatus tear using an accurate physical examination is essential to avoiding expensive and invasive additional tests .
unfortunately , only a few physical examinations that can detect isolated lesions of the supraspinatus alone are available in the clinical setting . the empty can ( ec ) ... | background : the supraspinatus tendon is the most commonly affected tendon in rotator cuff tears . early detection of a supraspinatus tear using an accurate physical examination is , therefore , important .
however , the currently used physical tests for detecting supraspinatus tears are poor diagnostic indicators an... |
it usually presents at , or soon after birth with hyperkeratotic verrucous dark - brown ridges . porcupine men and systematized epidermal naevus have also been used to describe these lesions .
based on the pattern of distribution , five clinical variants namely brocq type , lambert type , curth - macklin type , rhe... | ichthyosis hystrix is a rare autosomal dominant genodermatosis , characterized by persistent spiny hyperkeratotic scales which cover a significant part of the skin surface .
based on the pattern of distribution , five clinical variants namely brocq type , lambert type , curth - macklin type , rheydt type and bfverste... |
( caesalpiniaceae ) has great therapeutic implication in indian system of medicine and exerts an antipyretic , analgesic , antiinflammatory , and hypoglycemic effects [ 1 , 2 ] . over the past few years
, there has been an exponential growth in study of pharmacological properties of this plant [ 35 ] .
antioxidant ... | antioxidant potential of various extracts of cassia fistula was determined by the dpph , frap , fe3 + reducing power , and hydrogen peroxide scavenging assay .
methanolic extracts of cassia fistula showed the highest amount of phenolic and flavonoid content and reducing capacity , whereas hexane extracts exhibited th... |
betathalassemia major is one of the commonest hereditary hemoglobinopathies , characterized by reduced or absent betaglobin chain synthesis 1 .
management is based on regular blood transfusions to suppress ineffective erythropoiesis , with the goal to maintain pretransfusion hemoglobin concentration above 90 g / l 2 ... | key clinical messagepatients with higher liver iron stores are likely to have a worse cardiac outcome following noncompliance with chelation .
cardiovascular magnetic resonance identifies myocardial siderosis allowing optimization of iron chelation regimes .
diabetes puts thalassemic patients at increased risk of m... |
spontaneous central vein thrombosis is a rare but potentially serious condition as it can present with a fatal pulmonary embolism .
activated protein c resistance ( apc - r ) due to homozygous factor v leiden mutation is an exceptional cause of spontaneous central venous thrombosis . we describe here a right - sided ... | spontaneous central vein thrombosis is a rare and potentially fatal condition in critical care setting .
activated protein c resistance due to homozygous factor v leiden mutation is an exceptional cause of central venous thrombosis .
we recently treated a healthy female student who presented with acute febrile illn... |
sarcomatoid carcinomas of the lung are very uncommon tumors , comprising between 0.3 and 3% of all non - small lung carcinomas .
it is a heterogeneous group of poorly differentiated carcinomas with two cell types : sarcomatoid or sarcomatous morphology with giant and/or spindle cells .
their clinical presentation i... | context : lung tumors are very heterogeneous histological entities .
pulmonary sarcomatoid carcinoma is a subset of tumors characterized by specific histological features .
their poor prognosis compared to other lung tumors is due to limited responses to different types of chemotherapy.case report : we report two p... |
patients with schizophrenia have a two- to threefold higher risk of premature death than those without schizophrenia .
this increased mortality is accounted for by a combination of factors , such as lifestyle factors , high suicide rates ( especially in young male patients soon after diagnosis ) , premature developme... | patients with schizophrenia have a two- to three - fold increased risk of premature death as compared to patients without this disease .
it has been established that patients with schizophrenia are at a high risk of developing cardiovascular disease . moreover ,
an important issue that has not yet been explored is ... |
though the most common presentation of obstructive uropathy is urosepsis , this disorder may be associated with hyponatremia and loss of salt in the urine .
the present case posed a diagnostic challenge because despite the presence of an obstructive salt losing uropathy , the urinary salt concentration was paradoxica... | a 6-month - old hyponatremic female with failure to thrive had low urinary sodium concentration .
renal sonography revealed a duplex left collecting system with obstruction of the upper moiety as a blind - ended ectopic ureterocele extending to the bladder base .
the echogenicity of the urine within the upper pole ... |
secondary brain stem injury is associated with transtentorial herniation , and manifests as duret hemorrhages .
such an injury has been considered a terminal brain stem event with a high morbidity and mortality , sometimes discouraging continuation of care . however , there have been rare instances where patients h... | backgroundsecondary brain stem injury is associated with transtentorial herniation , and manifests as duret hemorrhages .
such an injury has been considered a terminal brain stem event with a high morbidity and mortality , sometimes discouraging continuation of care . however , there have been rare instances where ... |
rhinitis sicca or generally speaking dry nose is a rather frequent problem involving many people .
many symptoms during dry nose could be encountered ranging from subjective sensation of the dry nose and itching up to mild burning , nasal obstruction , crusting associated with unpleasant smell , epistaxis , and dimin... | objectives . the safety and efficacy of ectoine nasal spray and ectoine nasal spray with dexpanthenol in the treatment of rhinitis sicca were evaluated in two studies .
design and methods .
two noninterventional observational studies were performed to evaluate the efficacy and safety of a nasal spray containing ect... |
breast cancer remains a significant public health challenge both in the united states and worldwide .
while breast cancer is potentially curable when detected at an early stage , it remains incurable in the metastatic setting .
hence , there has been a major effort to detect breast cancer early , optimize the manag... | although substantial progress has been made in the screening and management of breast cancer , globally it remains the most common cause of cancer and cancer death in women .
while breast cancer is potentially curable when detected at an early stage , it remains incurable in the metastatic setting .
thus , given it... |
world - wide , at least 2.8 million people die each year as a result of being overweight or obese and an estimated 35.8 million ( 2.3% ) of global dalys are caused by overweight or obesity .
overweight and obesity lead to adverse metabolic effects on blood pressure , cholesterol , triglycerides ( tg ) and insulin res... | background : regular moderate intensity physical activity and lipid lowering effects of nigella sativa ( n. sativa ) supplementation may be appropriate management for sedentary overweight females . therefore , the aim of the present study was to examine the effects of long - term n. sativa supplementation and aerobic t... |
gene fusion leading to the formation of multidomain proteins is one of the major routes of protein evolution .
gene fusions characteristically bring together proteins that function in a concerted manner , such as successive enzymes in metabolic pathways , enzymes and the domains involved in their regulation , or dna ... | backgroundgene fusions can be used as tools for functional prediction and also as evolutionary markers .
fused genes often show a scattered phyletic distribution , which suggests a role for processes other than vertical inheritance in their evolution.resultsthe evolutionary history of gene fusions was studied by phyl... |
the medial entorhinal cortex ( mec ) is a major center for spatial navigation and memory .
we demonstrate that cannabinoid type-1 receptor - expressing gabaergic basket cells selectively innervate principal cells in layer ii of the rat mec that project outside the hippocampus , but avoid neighboring cells giving rise... | |
influenza a virus ( iav ) is a common infectious pathogen in humans , which occasionally causes influenza - associated encephalopathy ( iae ) .
iae is characterized by severe neurological complications , such as convulsive seizures , loss of consciousness , and abnormal behaviors.1,2
oseltamivir phosphate ( op ) is... | backgroundoseltamivir phosphate ( op , tamiflu ) is a widely used drug in the treatment of influenza with fever .
however , case reports have associated op intake with sudden abnormal behaviors . in rats infected by the influenza a virus ( iav ) , the electroencephalogram ( eeg ) displayed abnormal high - voltage amp... |
due to their collective significance in mediating the host response against pathogens , the genes of the interferon response have been an area of particular focus in the field of antiviral defense .
understanding the biology of interferon - stimulated genes is challenging because of the diversity in their specificity... | innate immunity is a theme of increasing interest for hiv research .
however , the term is overstretched to cover biological barriers , cellular systems , soluble factors , signaling pathways , and effectors and is inconsistently applied
. a clearer semantic classification of the components of innate immunity is ne... |
the term haemorrhagic disease of the newborn ( hdn ) was coined by charles townsend in 1894 to describe an acquired bleeding disorder in the newborn due to vitamin k deficiency .
nowadays , the term hdn is replaced by vitamin k deficiency bleeding ( vkdb ) , as neonatal bleeding is often not due to vitamin k defici... | vitamin k prophylaxis is recommended to prevent the hazard of haemorrhage caused by vitamin k deficiency in newborns .
the present dutch guideline recommends 1 mg of vitamin k1 orally at birth , followed by a daily dose of 25 g of vitamin k1 from 1 to 13 weeks of age for breastfed infants . since the introduction ... |
during the past decade , the patterns of diseases generated by shiga toxin - producing escherichia coli ( stec ) strains have changed from a clinical novelty to a global public health problem .
this group of e. coli strains can cause a spectrum of human diseases , ranging from symptom - free carriage to severe bloody... | background : during the last decade , the prevalence of foodborne diseases due to contaminated food as well as the outbreaks of diseases due to shiga toxin - producing escherichia
coli ( stec ) strains has increased.objectives:the aim of this study was to evaluate the prevalence and antibiotic resistance pattern of s... |
solubility of a drug is an important property that mainly influences the extent of oral bioavailability .
enhancement of oral bioavailability of poorly water soluble drugs is the most challenging aspect of drug development .
most of the new chemical entities suffer from low bioavailability due to their low aqueous ... | the objective of the present work was to enhance the solubility and dissolution of practically water - insoluble drug raloxifene hcl ( rlx ) , for the same two approaches that were used .
in the first approach , drug was kneaded with hydroxypropyl--cyclodextrin ( hpcd ) , and in the second one drug was cogrinded with... |
trauma is still one of the leading causes of death among people aged 45 and younger .
the annual economic burden of direct and indirect costs in germany alone is estimated to be around 40 billion euros annually . due to the heterogeneity of trauma , complex injury patterns , and broad variability of therapeutic optio... | background .
the molecular mechanisms of the immune response after polytrauma are highly complex and far from fully understood . in this paper , we characterize a new standardized polytrauma model in rats based on the early molecular inflammatory and apoptotic response . methods .
male wistar rats ( 250 g , 610/gr... |
emergency medical services ( ems ) providers constantly deal with situations associated with high stress and anxiety ( 1 ) . given the serious nature of burn injuries , dealing with burn emergencies
pre - hospital emergency teams and hospital staff face various problems , particularly in times of major burn emergenci... | background : medical emergency staff complete understanding of the nature of resiliency in burn events is a prerequisite for improving the quality of clinical service delivery in pre - hospital burn events.objectives:the present study aimed to describe resiliency in view of medical emergency staff in burn events.materi... |
all the chemicals used were of analytical grade and purified by standard methods prior to use .
the melting points were measured using a stuart scientific melting point apparatus smp3 ( uk ) and are uncorrected .
the nmr spectra were taken using bruker dpx 300 mhz instrument at organic chemistry institute , bonn , ... | cytohesins are small guanine nucleotide exchange factors that stimulate adp ribosylation factors , ras - like gtpases , which control various cellular regulatory networks ranging from vesicle trafficking to integrin activation . a small molecule secinh3 ( 1,2,4-triazole derivative ) in an aptamer displacement assay as ... |
lyme disease ( ld ) is an increasing health burden on the australian community requiring wider diagnostic recognition.1
borrelia burgdorferi sensu lato ( bbsl ) are closely related spirochetal species that are the causative agents of ld in humans.2 the author has previously reported the endemic presence of ld in aust... | backgroundlyme disease ( ld ) is an emerging infectious disease in australia .
there has been controversy regarding endemic lyme disease in the country for over 20 years .
borrelia burgdorferi sensu stricto ( bbss ) and sensu lato ( bbsl ) are closely related spirochetal species that are the causative agents of ld ... |
tinnitus , defined as the perception of sound that results exclusively from activity within the nervous system without any corresponding mechanical , vibratory activity within the cochlea , and not related to external stimulation of any kind
it is argued that approximately one third of the population experiences tin... | treatment programs based on a neurophysiological model have shown a positive effect on anxiety and depression in tinnitus patients .
the aim of this paper was to assess the long - term effect of tinnitus habituation therapy .
sixty - eight individuals were treated with a comprehensive therapy program .
the degree... |
primary classical hodgkin 's lymphoma ( hl ) of the gastrointestinal tract ( git ) are rare lymphoproliferative neoplasm representing less than 5% of git lymphomas , predominantly confined to the small intestine .
diagnosis of the primary lesion requires the lack of peripheral or mediastinal lymphadenopathy , normal ... | primary intestinal lymphoma is a rare lymphoproliferative neoplasm of the small intestine .
the primary nature is established on the basis of lack of evidence of lymphoma on chest x - ray , computerized tomographic scan , peripheral blood or bone marrow puncture .
tumor involvement is limited to the gastrointestina... |
gastrointestinal stromal tumors ( gists ) are mesenchymal tumors that may develop anywhere within the gastrointestinal tract .
they are defined as cd117-(c - kit ) or cd34-positive spindle cell tumors and are derived from interstitial cells of cajal .
the most common site of growth is the stomach , accounting for 6... | a 76-year - old man presented to our hospital with abdominal distention and loss of appetite .
the 10% of weight lost relative to this patient in 1 month .
abdominal computed tomography and magnetic resonance imaging revealed a giant mass , with a major axis of 23 cm , containing solid components , not involving th... |
live intact tissues can be imaged using two - photon laser scanning microscopy ( tplsm ) either intravitally with the animal anesthetized or by isolating and imaging tissue explants maintained in oxygen - supplemented media at controlled temperature ( 15 ) . using a femtosecond pulsed - emission laser and near infrare... | immunological phenomena that were once deduced from genetic , biochemical , and in situ approaches are now being witnessed in living color , in three dimensions , and in real time .
the information in time - lapse imaging can provide valuable mechanistic insight into a host of processes , from cell migration to signa... |
japan is one of the world s fastest aging societies , and the increase in the elderly
disabled requiring long - term care is becoming a social problem .
according to the long - term
care insurance report 2012 issued by the ministry of health , labour and welfare ( mhlw ) ,
5,306,000 people , including the bedri... | [ purpose ] this study examined the quality of life ( qol ) of homebound elderly hemiparetic
stroke patients and factors that affect it . [ subjects ] the subjects of the study were 21
homebound elderly hemiparetic stroke patients who were 65 years old or over and required
care for daily living ( 12 males and 9 ... |
spontaneous bacterial peritonitis ( sbp ) is defined as an infection of ascetic fluid without a proven intra - abdominal source ( 1 , 2 ) .
sbp is a common and severe complication in cirrhotic patients ( 3 ) , and is the major cause of mortality and morbidity among them ( 4 ) .
bacterial infection due to complicati... | backgroundthe diagnosis of peritonitis as a complication of cirrhosis is an important clinical problem.objectivesthe aim of this study was to evaluate serum c - reactive protein levels as a diagnostic factor for spontaneous bacterial peritonitis ( sbp ) in child patients with liver disease.methodsin this study , 150 ch... |
attempted suicide is self injury with a desire to end one 's life but does not lead to death .
large amounts of undesirable behavior results in suicidal behavior that is an expression of a specific form of vulnerability .
patients with hopelessness systematically misconstrue experiences in a negative manner and ten... | background : suicide is a psychiatric emergency .
stressors in life and social variables ( like marital status , family , and social support ) are among the determinants of suicide .
hopelessness and suicidal intent are among the psychological variables that have shown promise in the prediction of suicide.aims and ... |
in recent years , increasing attention has been devoted to the synthesis of various nanostructured batio3 , such as nanoparticles , nanocubes , nanorods , nanowires , and nanotubes , because of the dependence of their ferroelectric and piezoelectric properties on the dimension and size , which is essential for realizin... | novel bowl - like single - crystalline batio3 nanoparticles were synthesized by a simple hydrothermal method using ba(oh)28h2o and tio2 as precursors .
the as - prepared products were characterized by xrd , raman spectroscopy , sem and tem .
the results show that the bowl - like batio3 nanoparticles are single - cr... |
one of the major reasons for patients presenting at a primary care practice is pain ; according to surveys , around 40% of patients consult their family doctor mainly owing to pain , and 2040% of those have been suffering from pain for more than 6 months [ 1 , 2 ] .
high prevalence rates for chronic pain have been re... | the family practitioner plays an important role in the prevention , diagnosis , and early management of chronic pain . he / she is generally the first to be consulted , the one most familiar with the patients and their medical history , and is likely the first to be alerted in case of inadequate pain control or safety ... |
asthma is one of the most prevalent diseases in children and adolescents worldwide and the leading reason for inability in children .
the prevalence of asthma has been reported variously in iran ( 4 - 7% ) and worldwide ( 8 - 12% ) . also , the prevalence in children is so growing worldwide that it has increased by 5... | background : incidence of asthma in adolescents leads to variations in family status , roles and interaction with peers for them , which could be a source of stress and psychological tensions in them .
therefore , the present study was conducted to investigate the effect of orem s self - care model on perceived stres... |
after colostomy , the nonfunctioning intestinal segment presents inflammatory alterations comprising a nosological entity known as diversion colitis ( dc).1 the preferred treatment for dc is intestinal transit reconstruction which , in most cases , resolves the inflammatory process.2 ma et al.3 analyzed 21 cases of d... | objectives : to study the effect of shortchain fattyacids on atrophy and inflammation of excluded colonic segments before and after the development of diversion colitis.introduction:diversion colitis is a chronic inflammatory process affecting the dysfunctional colon , possibly evolving with mucous and blood discharge ... |
zfin ( http://zfin.org ) is a curated database of zebrafish genetic and genomic data including genes , mutants , transgenic lines and constructs , genotypes , phenotypes , gene expression , anatomical structures , orthology , nucleotide and protein sequences and reagents such as morpholinos and antibodies .
a table i... | zfin , the zebrafish model organism database ( http://zfin.org ) , is the central resource for zebrafish genetic , genomic , phenotypic and developmental data .
zfin curators manually curate and integrate comprehensive data involving zebrafish genes , mutants , transgenics , phenotypes , genotypes , gene expressions ... |
the use of 18-fluorodeoxyglucose positron emission tomography - computed tomography ( 18-fdg pet / ct ) in the field of oncology is well - established ; however , 18f - fdg is not tumor specific . aside from physiological uptake fdg
knowledge of these fdg - avid non - malignant lesions is essential for accurate pet i... | xanthogranulomatous pyelonephritis ( xgnp ) is an uncommon condition characterized by chronic suppurative renal inflammation that leads to progressive parenchymal destruction .
this condition can clinically present as recurrent urinary tract infections , flank pain , hematuria , and occasionally sepsis , and weight l... |
the ciliate diploplastron affine is a common species of rumen fauna in the domesticated ruminants ( dogiel 1927 ) . to date , the fibrolytic properties of this protozoan were studied by coleman ( 1985 ) whereas its ability to digest and utilize starch is not well known .
the objectives of the reported studies were to... | the ciliate diploplastron affine is known as a common species of the rumen fauna in cattle and sheep .
this protozoon is able to digest cellulose , whereas its amylolytic activity is not well known .
the objective of the reported studies was to examine the ability of d. affine to digest starch and to use this polys... |
wild - type ( c57bl/6j ) and sod1 ( b6.cg-tg(sod1*g93a)1gur/j , stock # 004435 ) mice were obtained from jackson laboratories ( bar harbor , me , usa ) .
intraocular pressure elevation was induced by anterior chamber microbead injections as originally described by sappington et al .
however , we applied a recently ... | purposebesides primary neurotoxicity , oxidative stress may compromise the glial immune regulation and shift the immune homeostasis toward neurodegenerative inflammation in glaucoma .
we tested this hypothesis through the analysis of neuroinflammatory and neurodegenerative outcomes in mouse glaucoma using two experim... |
anaphylaxis is a medical emergency that is manifested by a broad spectrum of signs and symptoms that can be similar to those of other diseases .
vascular collapse and bronchospasm are hallmarks of this condition , but neither is universally present .
other findings , such as flushing or urticaria , are easily overl... | anaphylaxis is a fulminant , unexpected , immunoglobulin e - mediated allergic reaction that can be triggered by multiple agents .
common causative agents include neuromuscular blocking drugs , latex , antibiotics , colloids , hypnotics , and opioids .
fentanyl citrate , however , is an extremely unusual cause of a... |
issues pertaining to biology and therapy of malignancies occurring amongst adolescent and young adults ( aya ) have largely remained neglected till last few years when data emerging from epidemiology and outcome registries suggested the need for active research in this field . over the years , improvements in the under... | background : the uniqueness of adolescent and young adult ( aya ) non - hodgkin lymphomas ( nhl ) with respect to biology and treatment have largely remained unanswered due to marked heterogeneity in treatment , paucity of prospective , or retrospective studies and poor representation of aya in clinical trials .
this... |
surfactant - like peptides
( slps ) have a remarkable ability to self - assemble
into different nanostructures , primarily due to their amphiphilic
nature .
for example , they can aggregate into high aspect ratio structures
while displaying bioactive peptides .
slps are a class of amphiphilic
peptide comp... | we investigate the properties of
an antimicrobial surfactant - like
peptide ( ala)6(arg ) , a6r , containing a cationic
headgroup .
the interaction of this peptide with zwitterionic ( dppc )
lipid vesicles is investigated using a range of microscopic , x - ray
scattering , spectroscopic , and calorimetric m... |
in the mid 1960s , brinley
presented a novel plotting
method to consider the
relationship between response times in young and older
adults across a variety
of tasks with varying levels of cognitive difficulty
.
the average response times
for both the young and older groups of adults on each task was
p... | by plotting response times of young and older adults across a variety of tasks , brinley spurred investigation and debate into the theory of general cognitive slowing
. though controversial , brinley plots can assess between - task differences , the impact of increasing task demand , and the relationship between resp... |
some cyclists use the bicycle as a means of transportation , others ride for recreation , and some are competitive cyclists .
the repetitive movements of cycling put cyclists at a risk of overuse injuries , particularly to the leg joints ( knee and ankle ) . during 1985 ,
about 8.36% of causalities seen in the emer... | introduction : bicycling is one of the most enjoyable aerobic exercises recommended for the promotion of an individual 's health
. the eastern province of saudi arabia has seen a huge increase in the number of people who cycle .
people have different goals for bicycling , but the injuries they sustain are common . ... |
our patient was a 76-year - old man with a coronary artery bypass graft due to unstable angina . during the postoperative period ,
a blood gas analysis showed a paco2 concentration of 45 mmhg , pao2 concentration of 63 mmhg , and a ph of 7.40 during intermittent mandatory ventilation at a rate of 12 breaths per minut... | tracheostomy is a relatively common surgical procedure that is performed easily in an operating room or intensive care unit .
open tracheostomy is needed in patients requiring prolonged ventilation when percutaneous tracheostomy is inappropriate .
sometimes , it is difficult to achieve bleeding control in the perit... |
over the past two decades , numerous studies have provided evidence that sleep enhances memory consolidation .
it has been initially shown that consolidation of declarative / episodic memories is enhanced by early sws - rich periods of sleep whereas procedural memory rather benefits from late sleep during which rem s... | memories are not stored as they were initially encoded but rather undergo a gradual reorganization process , termed memory consolidation .
numerous data indicate that sleep plays a major role in this process , notably due to the specific neurochemical environment and the electrophysiological activity observed during ... |
type 2 diabetes mellitus affects about 5% of the german population.1 eighty percent of patients with type 2 diabetes are treated with diet or oral antiglycemic drugs ( oads).2 for successful treatment of patients with diabetes , we have different therapy options , such as modification of eating behavior and physical ex... | objectivelong - term outcomes after participation in a structured diabetes treatment and teaching program ( dttp ) for patients with diabetes without insulin use , primarily based upon postprandial urine glucose self - monitoring ( ugsm).methodsa total of 126 patients took part in the dttp in a university outpatient de... |
as indicated in a recent systematic review relating to canada 's physical activity guidelines for older adults , exercise interventions ( comprised of aerobic and strength training ) in older adults can maintain or improve functional abilities .
less is known about the role of flexibility in the maintenance or improv... | background . as indicated in a recent systematic review relating to canada 's physical activity guidelines for older adults , exercise interventions in older adults can maintain or improve functional abilities .
less is known about the role of flexibility in the maintenance or improvement of functional abilities , an... |
in each country , the government and health system are responsible for providing sufficient and cost - effective health and curative care . moreover , increasing the accessibility and utilization of health services are critical for improving health systems .
primary health care is largely financed and delivered by pu... | background : protecting households from risk of impoverishment due to out - of - pocket costs in health care is a major challenge for health systems .
therefore , this study aimed at evaluating some health expenditure of inpatient and outpatient care as well as assessing the predictors of catastrophic costs for inpat... |
recent technological advances in endoscopy have supported a flood of new diagnostic methods , collectively reported as consensus terminology .
the narrow band imaging ( nbi ) used in this study fits into the well - studied image - enhancing endoscopy ( iee ) category [ 225 ] as autofluorescence imaging ( afi ) [ 21... | introduction . this study examined whether magnifying endoscopy with nbi observation ( me - nbi ) could be useful selecting the appropriate treatment for submucosal invasive cancer ( sm cancer ) .
patients and methods .
we analyzed 515 cases of colon tumors excised endoscopically or surgically .
we classified cap... |
immunosuppressive agents are the major therapy in focal segmental glomerulosclerosis ( fsgs ) and in aplastic anemia , and therefore it generally believed that immunological mechanisms contribute to both diseases .
the pathogenesis of fsgs is unknown but appears to be the result of a lymphokine or cytokine , which le... | the pathogenic mechanism of focal segmental glomerulosclerosis ( fsgs ) and aplastic anemia are associated with immunologic events which lead to glomerular cell injury or hematopoietic cell destruction .
we present an extremely rare case of fsgs with aplastic anemia in a 30-yr - old woman .
the laboratory examinati... |
the increasing incidence of complex percutaneous coronary intervention ( pci ) is accompanied by risks of device fracture or dislodgement .
guide wire fractures during pci are very rare , but in such cases , life - threatening complications such as embolization , thrombus formation and perforation may occur . althoug... | guide wire fractures during percutaneous coronary intervention ( pci ) are very rare , but when they do occur they may lead to life - threatening complications , such as embolization , thrombus formation and perforation . in cases when percutaneous retrieval has failed , surgical extraction of the remnant fragments is ... |
in china , hepatocellular carcinoma ( hcc ) is the fifth most common malignant cancer and the third leading cause of cancer - related mortality . about 90% of patients with hcc also have various levels level of liver cirrhosis , mainly caused by chronic liver disease after hepatitis b and c , especially in patients ass... | background and objectives : patients undergoing synchronous open splenectomy and hepatectomy ( osh ) for concurrent hepatocellular carcinoma ( hcc ) and hypersplenism usually have major surgical trauma caused by the long abdominal incision .
surgical procedures that contribute to rapid recovery with the least possibl... |
osteomas are the most common benign tumors of the nose and paranasal sinuses , with an incidence that ranges between 0.43 - 1% ( 1 , 2 ) .
they occur most commonly within the frontal sinus ( 52% ) , followed by the ethmoid ( 22.0% ) , the maxillary sinus ( 5.1% ) , and the sphenoid ( 1.7% ) ( 1 ) .
it is very rare ... | osteoma is the most common benign tumor of the paranasal sinuses .
turbinate osteomas are very rare and only four middle turbinate , one superior turbinate and one inferior turbinate osteoma cases have been reported .
we present a rare case of osteoma of the left middle turbinate in a patient presented with unilate... |
systemic sclerosis ( ssc ) , or scleroderma , is a chronic multisystem disorder of small vessels and connective tissues characterized by diffuse fibrosis of the skin and internal organs , most frequently the lungs and gastrointestinal tract .
the disease has a 3:1 female predilection and typically occurs in the third... | interstitial lung disease and pulmonary hypertension ( ph ) are the most common cardiopulmonary findings in patients with systemic sclerosis ( ssc ) .
about two thirds of patients suffering from ssc develop scleroderma interstitial lung disease .
ph is present in about 20% of ssc patients and is typically associate... |
the movement of organelle dna to the nucleus has been , and remains , a driving force in fashioning eukaryotic genomes ( timmis et al . 2004 ; kleine et al .
early on in both mitochondrial and plastid evolution , there was a massive migration of organelle genes to the nuclear genome ( gray et al .
2009 ) ; thus , p... | the abundance of nuclear plastid dna - like sequences ( nupts ) in nuclear genomes can vary immensely ; however , the forces responsible for this variation are poorly understood .
the limited transfer window hypothesis predicts that species with only one plastid per cell will have fewer nupts than those with many pl... |
statins are used to lower serum cholesterol concentrations in the primary and secondary prevention of cardiovascular disease ( 1 ) . in randomized trials ,
the use of statins has demonstrated 30% reductions in atherosclerotic end points without serious morbidity .
the pleiotropic effects of statins , indirectly rel... | hmg - coa reductase inhibitors ( statins ) are widely used to treat hypercholesterolemia . among the adverse effects associated with these drugs
are statin - associated myopathies , ranging from asymptomatic elevation of serum creatine kinase to fatal rhabdomyolysis .
fluvastatin - induced fatal rhabdomyolysis has ... |
it refers to abnormal hearing of sound heard during metabolism and not from an external sound source .
the most common cause of vibratory tinnitus is intracranial vascular disease , such as aneurysm and arteriovenous malformation.1 ) the authors performed excisional biopsy on pulsatile lip masses of 46 year old male ... | tinnitus is one of the most common symptoms in an audiologic field .
it can be classified as either as subjective or objective ; former referring to the sensation heard by both patient and examiner .
pulsatile tinnitus is perceived as sounds that vary in frequency , intensity and duration .
the cause of pulsatile... |
falls in adults pose a major health concern , are a well - known public health problem,1 and are the main cause of injury , hospitalization , disability , poor quality of life , depression , and mortality in older adults.2,3 about 30%40% of adults in the usa report falling at least once per year,4 but less than half di... | backgroundthe purpose of this study was to examine the relationship between self - reported falls , doctor - diagnosed knee osteoarthritis ( oa ) , and health - related quality of life ( hrqol ) .
we hypothesized that falls and knee oa would be associated with poor hrqol on both disease - specific and generic measure... |
colorectal cancer ( crc ) is the fourth most commonly diagnosed malignant disease worldwide , with over 1 million new cases and approximately 5,00,000 deaths each year . incidence and deaths from this cancer are generally increasing , most of all in the developed world and urban areas of the developing world .
age ad... | background : colorectal carcinoma ( crc ) is the fourth most commonly diagnosed malignant disease worldwide , with over 1 million new cases and approximately 5,00,000 deaths each year.aims and objectives : this prospective observational study was done to study the clinicopathological characteristics of crc including mu... |
though the majority of us physicians have seen a patient receive poor quality health care due to patient race or ethnicity , responding to these witnessed practices can be challenging.1 many faculty may be uncertain about the link between an observed behavior and clinical outcomes.15 faculty often avoid giving feedback... | clinical teachers often observe interactions that may contribute to health care disparities , yet may hesitate to teach about them .
a pedagogical model could help faculty structure teaching about health care disparities in the clinical setting , but to our knowledge , none have been adapted for this purpose . in thi... |
musculoskeletal disorders ( msds ) are prevalent among workers in the construction industry which warrants heavy physical work , often necessitating inappropriate working postures for prolonged periods , which significantly increases morbidity and considerably decreases the work ability . the brick manufacturing indust... | background : a variety of musculoskeletal disorders and discomfort are seen among brick kiln workers , where heavy physical work is associated with awkward working postures and manual handling of materials , leading to significant morbidity.materials and methods : this cross - sectional study was conducted in unorganiz... |
among the different types of forearm motor activities required in simple day - to - day tasks , two primary types of movements required are closing and opening of hand for grasping and releasing objects of different sizes respectively .
research shows that about 80% of stroke survivors lack in movement control and co... | neurological disorders often manifest themselves in the form of movement deficit on the part of the patient .
conventional rehabilitation often used to address these deficits , though powerful are often monotonous in nature .
adequate audio - visual stimulation can prove to be motivational . in the research present... |
our institutional review board approved our retrospective study with a waiver of informed consent . from september 2003 to july 2006 , we enrolled 199 patients who underwent integrated pet / ct and surgical staging and were diagnosed with stage t1 nsclc at ct ( retrospective review and reanalysis of all ct data obtaine... | objectivewe aimed to compare the prognoses of patients with pathologically true negative ( p - tn ) n2 and pet / ct false negative ( fn ) results in stage t1 non - small cell lung cancer ( nsclc).materials and methodsour institutional review board approved this retrospective study with a waiver of informed consent .
... |
we present a patient who developed pneumomediastinum after an elective bilateral preperitoneal laparoscopic hernia repair .
as newer approaches to inguinal hernia repair are performed , newer complications of these techniques are being encountered .
laparoscopic approaches to inguinal hernia repair have be... | background : as new approaches to herniorrhaphy are popularized , new complications are being encountered .
pneumomediastinum is one such complication.methods:we present a patient who developed pneumomediastinum after an elective bilateral preperitoneal laparoscopic hernia repair.results:the patient was observed and ... |
. complications due to cholelithiasis and subsequent hospital admissions are responsible for enhanced morbidity and mortality in addition to large expenses and large numbers of hospital beds needed by these patients . for
most surgeons , asymptomatic lithiasis does not require surgical treatment , which is only requi... | objectivesto evaluate the prevalence of cholecystopathy in chronic renal patients awaiting kidney transplants.introductionthe prevalence and management of cholelithiasis in renal transplant patients is not well established.methodsa total of 342 chronic renal failure patients on the waiting list for a kidney transplant ... |
nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea .
a biopsy from the lesion can demonstrate the scleroderma pattern , i.e. , keloid pattern or mixed type .
we present a case of systemic sclerosis in a 50-year - old female who developed nodular scl... | backgroundnodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea .
a biopsy from the lesion can demonstrate the scleroderma pattern , i.e. , keloid pattern or mixed type .
treatment is challenging , and several treatments modalities have been reported w... |
seven - transmembrane receptors are a family of signaling proteins that bind hormones , autacoids , and neurotransmitters to mediate a myriad of cellular functions .
like all proteins , these exist in collections of tertiary conformations called protein ensembles ; receptors sample these conformations according to ch... | seven - transmembrane receptors are commonly coupled to multiple signaling pathways in cells .
the simple model describing agonists for these receptors as producing a common active state to induce uniform activation of the pathways linked to the receptor has been shown to be untenable in light of a large body of data... |
identification is a matter of paramount importance in any crime investigation . even though dna and fingerprints are the time - tested methods , these evidences are not always available at the investigation sites . in such circumstances , it is necessary to apply different and less - known techniques . a new area of in... | aim : to evaluate the uniqueness and to define a standard method for the analysis of lip prints.materials and methods : lip prints of 100 students were taken using scotch tape without any distortion .
these prints were then scanned for the digital analysis . using adobe photoshop 7 software
an attempt was made to t... |
intraventricular hemorrhage ( ivh ) is a significant cause of preterm morbidity and mortality , with approximately 12,000 infants developing ivh every year in the united states . within the population of very low birth weight ( vlbw ; < 1500 g ) infants , the incidence of ivh has been estimated at 20% .
however , the... | objectiveto determine the association between antenatal steroids administration and intraventricular hemorrhage rates.methodswe used cross - sectional data from the california perinatal quality care collaborative during 2007 - 2013 for infants 32 weeks gestational age . using multivariable logistic regression
, we e... |
patients presenting with recent onset of low back pain and dermatomal sensory loss are often evaluated for common entities including disc herniation , degenerative lateral recess stenosis , nerve sheath tumor , and meningioma .
described herein is a patient presenting with such symptoms who was found to have an extra... | the identification of a soft tissue chondroma within the spine represents a rarity and is typically not included within the differential diagnosis for patients with sensory complaints of the leg .
the authors describe 46-year - old female presenting with 3-week history of decreased sensation and paresthesias of the l... |
a crucial property of esthetic restorative materials is their long - term stability in the oral environment : although great improvements have been achieved during recent years , color stability is still a problem .
composite resins are susceptible to various degrees of discoloration after prolonged exposure to the o... | background : the purpose of this in vitro study was to evaluate surface discoloration of three microhybrid composite resins ( esthetx hd , clearfil ap - x , gradia direct ) and five nanohybrid composite resins ( ceramx , gc kalore , g - aenial , grandio , grandioso ) , after staining and bleaching procedures.materials ... |
currently , more than 150 000 partial or complete hiv genome sequences are available in the central hiv database at los alamos national laboratory ( 1 ) ; these data are crucial for the development of drugs against aids .
analysis of hiv sequence data is challenging , however , since hiv is among the most geneticall... | detecting recombinations in the genome sequence of human immunodeficiency virus ( hiv-1 ) is crucial for epidemiological studies and for vaccine development .
herein , we present a web server for subtyping and localization of phylogenetic breakpoints in hiv-1 .
our software is based on a jumping profile hidden mark... |
a literature search using the title terms metabolic syndrome and diabetes was conducted in pubmed .
we limited the search to articles that were written in english . because the who was the first to release its definition , in 1998 , we started our search for articles published that year and continued through apri... | objective our objective was to perform a quantitative review of prospective studies examining the association between the metabolic syndrome and incident diabetes.research design and methods using the title terms diabetes and metabolic syndrome in pubmed , we searched for articles published since 1998.resultsbase... |
patients with heart failure ( hf ) are suggested to have a diabetes mellitus ( dm ) prevalence of 841%,1 which is associated with increased mortality and morbidity.2 , 3 treatment of dm in hf patients is controversial , because many contemporary therapies used for dm treatment , including thiazolidine , are contraindic... | abstractbackgroundheart failure ( hf ) and diabetes mellitus ( dm ) often coexist .
treatment of dm in hf patients is challenging because some therapies for dm are contraindicated in hf .
although previous experimental studies have reported that dipeptidyl peptidase4 ( dpp4 ) inhibitors improve cardiovascular funct... |
evolution and speciation are believed to be driven in large part by the insertion of transposable elements ( tes ) within eukaryotic genes .
the tes can integrate into a gene with either a forward or reverse pattern according to the transcription directionality of the inserted gene and the transposase gene .
when i... | in exonization events , ds1 may provide donor and/or acceptor sites for splicing after inserting into genes and be incorporated into new transcripts with new exon(s ) . in this study ,
the protein variants of ds1 exonization yielding additional functional profile(s ) were studied .
unlike ds exonization , which cre... |
acute renal failure is a frequent feature at diagnosis of multiple myeloma ( mm ) .
it is present in 2055% of patients with a newly diagnosed mm , among whom 23% require dialysis .
renal impairment is a poor prognostic factor in patients with mm as it is associated with an increased morbidity and early mortality ra... | acute renal failure is a frequent feature in patients with multiple myeloma ( mm ) .
mm - related renal insufficiency may improve after autologous haematopoietic stem cell transplantation ( autohsct ) even in patients initially requiring dialysis .
herein , we report on two unusual cases of late improvement in rena... |
its causes are varied , but in all cases it is characterized by the appearance of local acute or chronic inflammatory changes occurring in the wall of the trachea .
these changes lead to degradation over time and pathological restructuring of constituent structures and their replacement by fibrous tissue .
they are... | we present a case of one - stage radical surgical treatment of a 24-year - old female patient with cicatricial granulating tracheal stenosis after tracheostomy complicated by esophageal - tracheal fistula and an extensive defect of the anterior wall of the trachea after numerous unsuccessful attempts to correct the nar... |
yttria - stabilized tetragonal zirconia polycrystal ( y - tzp ) ceramic has extensive applications in restorative dentistry due to excellent mechanical properties and biocompatibility .
zirconia computer - aided design and computer - aided manufacturing ( cad / cam ) systems have enabled the fabrication of y - tzp de... | objectives : studies on the effect of coloring procedures on the bond strength of zirconia to resin cement are lacking in the literature . this study evaluated the effect of dipping of zirconia ceramic in different liquid color shades on the microtensile bond strength ( mtbs ) of zirconia ceramic to resin cement.materi... |
low - back pain is one of the most common human morbidities worldwide , which is damaging individually , socially and economically .
most of the low - back pains are non - specific though specific ones need more complicated and more expensive treatments .
sciatica or lumbar radiculopathy is one of these specific lo... | background : low - back pain is one of the most common human morbidities worldwide , which is damaging individually , socially and economically .
recent studies have shown that its prevalence is rising .
most of the low - back pains are non - specific though specific ones need more complicated and more expensive tr... |
genital self mutilation is a rare and a severe form of self - injurious behavior .
it is usually described in psychotic disorders , mostly in schizophrenia as a result of delusions and hallucinations.[13 ] in most cases , penile mutilation is common .
risk factors of genital self mutilation include commanding hallu... | genital self mutilation is a rare and a severe form of self - injurious behavior usually described in psychotic disorders , with delusions and hallucinations .
it has been ascribed to sexual conflicts , body image distortions , internalized aggression , and suicidal intent .
this phenomenon has been described in sc... |
obesity is a chronic metabolic nutritional disorder that has increased at an alarming rate in the last 20 years . in the us , 68% of the adults ( age 20 years ) and 18% of children ( 219 years ) are either obese or overweight as per the national health and nutrition examination survey [ 2 , 3 ] .
incidence... | objective . to summarize the recent studies on effect of conjugated linoleic acid ( cla ) on hepatic steatosis and hepatic and adipose lipid metabolism highlighting the potential regulatory mechanisms .
methods .
sixty - four published experiments were summarized in which trans-10 , cis-12 cla was fed either alone ... |
patients older than 70 years remain one of the fastest growing populations . in the usa alone
this group increased from 21.1 million in 1990 to over 25 million in 1999 , and is projected to reach nearly 36 million people by the year 2020 . with this in mind , the number of elderly patients presenting with an st - seg... | as the population ages the number of elderly patients presenting with acute myocardial infarction ( ami ) will continue to increase .
there has been no head - to - head trial of thrombolytic therapy versus primary percutaneous coronary intervention ( pci ) in this patient cohort , but there is evidence that favors pr... |
the use of titanium for dental implants and metal ceramic restorations , such as cast
restorations or partial dentures , has increased over the last years because of their
biocompatibility and optimum mechanical properties . however , low bond
strengths between titanium and composite veneering systems have been r... | objectivethis study evaluated the effect of three metal conditioners on the shear bond
strength ( sbs ) of a prosthetic composite material to cpti grade i having three
surface treatments .
material and methodsone hundred sixty eight rivet - shaped specimens ( 8.0x2.0 mm ) were cast and
subjected to polishing ( ... |
combined hepatocellular and cholangiocarcinoma ( chcc - cc ) is an uncommon subtype of primary liver cancer [ 1 , 2 ] .
the disease was first described in 1949 by allen and lisa and has been defined as the intimate intermingling of both a hcc component and cc component ( 2 ) .
allen and lisa described three group... | background .
the objective of this study was to examine the epidemiology , natural history , and prognostic factors of combined hepatocellular and cholangiocarcinoma ( chcc - cc ) using population - based registry .
methods .
the surveillance , epidemiology , and end results program database ( 19732004 ) was used... |
isoflavonoids and related compounds such as coumestrol have classically been categorized as phytoestrogens because these environmentally derived substances bind to the estrogen receptor ( er ) and increase uterine wet weight in immature rats and mice .
assessment of the binding affinities of isoflavonoids for er and ... | |
microarray analysis has been shown to be of crucial importance for the understanding of the genetic etiology of intellectual disability ( i d ) . with this technique
, numerous ( de novo ) copy number variations have been discovered leading to several circumscribed microdeletion syndromes.1,2 especially in patients i... | deletions of the 15q26 region encompassing the chromodomain helicase dna binding domain 2 ( chd2 ) gene have been associated with intellectual disability , behavioral problems , and several types of epilepsy . including the cases mentioned in ecaruca ( european cytogeneticists association register of unbalanced chromos... |
myxomas are the most common benign cardiac tumors , typically originating from the left atrium .
the right atrium is the second most common site where myxomas originate , accounting for 7%12% of cases .
only a few cases of myxomas arising from the right ventricle have been reported . in these cases , myxomas origin... | we report a rare case of an extremely large right ventricular myxoma involving the ventricular side of the tricuspid valve . the tumor was excised along with the entire posterior leaflet and part of the anterior leaflet .
the tricuspid valve was repaired by sliding valvuloplasty combined with ring annuloplasty . |
a 62-year - old woman was hospitalized for the further evaluation of her progressive chest discomfort for 10 days .
the patient had undergone total thyroidectomy 20 years earlier , and she has been managed for hypothyroidism since then .
seven years prior to admission , she was diagnosed with and managed for angina... | although thrombotic thrombocytopenic purpura ( ttp ) is a rare disease , when it develops in a post - cardiac surgery patient , it may have a fatal outcome .
since the frequency of early - onset thrombocytopenia in post - cardiac surgery patients is high , platelet concentrates are commonly transfused during postoper... |
language can be counted as the first cognitive enhancement , and the invention of writing also dramatically improved our cognitive ability to remember , to learn , and to communicate. today , with the aid of recent phenomenal development of biomedical technology , we are witnessing the emergence of more direct biologi... | among currently available technologies , transcranial direct current stimulation ( tdcs ) is one of the most promising neuroenhancements because it is relatively effective , safe , and affordable .
recently , lay people have begun to build or purchase the tdcs device to use it at home for treatment or as a cognitiv... |
s. oneidensis mr1 cultures were grown aerobically in lb ( 30 c , 200 rpm , 16 h ) to an optical density od
600 nm>1 . this culture ( 1 ml )
was used to inoculate lb ( 50 ml ) supplemented with 50 mm lactate and 25 mm fumarate in a 50 ml falcon tube .
the top of the tube was fastened shut and the culture ... | abstractexoelectrogenic bacteria can couple their metabolism to extracellular electron acceptors , including macroscopic electrodes , and this has applications in energy production , bioremediation and biosensing .
optimisation of these technologies relies on a detailed molecular understanding of extracellular electr... |
stroke involves rapid loss of brain function resulting from a disturbance in the blood
supply to the brain ; it often profoundly affects upper limb stability and movement capacity .
stroke is the third leading cause of death worldwide , and it is the leading cause of severe
disability in patients in the developed... | [ purpose ] the aim of this study was to compare the unaffected upper extremity of patients
with hemiparesis with that of healthy subjects in terms of function , pain , and tactile
sense . [ subjects and methods ] upper extremity evaluation parameters of 20 patients with
hemiparesis were compared with an age - ma... |
because of the aging population , the number of patients with age - associated joint disorders
has been increasing in japan .
these disorders are a major factor in the reduction of the
activities in the daily lives of the middle - aged .
in particular , the number of patients with
knee osteoarthritis ( oa ) h... | [ purpose ] superficial heat treatment is one of the most widely used physical therapies
for osteoarthritis ( oa ) . we clinically evaluated the effects of local heat treatment and
exercise therapy for knee oa , and evaluated the articular cartilage using magnetic
resonance imaging ( mri ) t2 mapping . [
subjec... |
we evaluated the performance of surveillance case definitions for zika virus disease recommended by the cste , who , paho , ecdc , and the singapore moh by using a cohort of 359 adult patients with suspected zika virus disease who came to the institute of infectious diseases and epidemiology , tan tock seng hospital , ... | we evaluated performance of 5 case definitions for zika virus disease surveillance in a human cohort during an outbreak in singapore , august 26september 5 , 2016 . because laboratory tests are largely inaccessible , use of case definitions that include rash as a required clinical feature are useful in identifying this... |
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