article stringlengths 0 826k | abstract stringlengths 174 4.34k |
|---|---|
the cytoskeletal components of endothelial cells play important roles in maintaining the fundamental structure of the thin inner layer of the blood vessels called the endothelium .
endothelial cells form a single cell layer on the surfaces of blood vessels and are therefore constantly subjected to both fluid shear st... | the cytoskeletal components of endothelial cells in the renal artery were examined by analysis of en face preparations under confocal laser scanning microscopy .
renal arterial endothelial cells were shown to be elongated along the direction of blood flow , while stress fibers ran perpendicular to the flow in the bas... |
puberty is an ordinary situation to adolescence and the progress of secondary sexual characteristics leads to the total differentiation between male and female .
also , the final height and posture of the male and female adolescents are determined in this period ( 1 ) . the menarche age is often considered for variou... | abstractbackgroundprediction of the onset of menstruation ( menarche age ) using height , weight and body mass index ( bmi ) is a major health procedure .
the present study was conducted to determine the relationship between anthropometric indices and menarche age in 488 girls 11 - 17 years in southern iran ( kish is... |
self - assembled
monolayers ( sams ) containing embedded dipolar groups
offer the particular advantage of changing the electronic properties
of a surface without affecting the sam ambient interface . here
we show that such systems can also be used for continuously tuning
metal work functions by growing mixed... | |
matrix producing carcinoma ( mpc ) of the breast is a rare variant of metaplastic carcinoma with a total of approximately 240 cases have been reported to date .
direct transition of carcinomatous elements to cartilaginous or osseous matrix without an intervening spindle cell component make the major diagnostic histop... | matrix producing carcinoma ( mpc ) of the breast is a very rare subtype of metaplastic carcinoma with heterelogous elements , which comprises < 0.1% of invasive breast carcinomas .
there are very few reports describing the cytological features of mpc . in this article
, we aimed to discuss cytological , histopathol... |
blood cultures are the gold standard for the diagnosis of sepsis , however , quantitative real - time amplification systems ( qpcr ) based on the bacterial 16s rdna have been suggested not as a replacement , but as a complementary diagnostic tool to blood cultures because they are faster and more sensitive than conve... | abstract
objective : to monitor the bacterial load in newborns with proven infections on the day of admission , 48 h and 7 days after treatment .
methods : real - time pcr ( qpcr ) targeting the 16s rdna .
results : the study recruited 17 newborns and the bacterial load was in general low ( < 50 cfu / ml ) . in... |
data from numerous epidemiological studies indicate that low cardio - respiratory fitness is a strong independent risk factor for all - cause and cardiovascular disease ( cvd ) mortality in asymptomatic individuals , persons with comorbid conditions ( hypertension , obesity , and type 2 diabetes mellitus ) , and those ... | purpose .
exercise tests represent an important clinical tool to evaluate cardio - respiratory fitness and to predict future adverse cardiovascular events . however , use of such tests in patients with rheumatoid arthritis ( ra ) is relatively uncommon despite well - established evidence that low exercise capacity an... |
three male patients and one female patient with sensory exotropia over 75 pd were included in this report .
none of the patients had other causes of exotropia such as third nerve palsy , any restrictive cause , orbital wall fracture or previous ocular surgery .
we carefully explained alternative approaches , namely... | in cases of extropia with an exodeviation angle over 50 prism diopter ( pd ) , a 3- or 4-muscle surgery is a rational option .
but , in patients with sensory exotropia , there is usually a strong preference for a monocular procedure to avoid surgery on the single seeing eye .
thus , we confined surgery to visually ... |
parkinson s disease ( pd ) is a progressive , chronic , neurodegenerative disease characterized by rigidity , tremor , bradykinesia and postural instability secondary to dopaminergic deficit in the nigrostriatal system.13 currently , disease - modifying therapies are not available , and levodopa ( ld ) treatment remain... | parkinson s disease ( pd ) is a progressive , chronic , neurodegenerative disease characterized by rigidity , tremor , bradykinesia and postural instability secondary to dopaminergic deficit in the nigrostriatal system .
currently , disease - modifying therapies are not available , and levodopa ( ld ) treatment remai... |
antigen
recognition is a key event during t cell activation . here
,
we introduce nanopatterned antigen arrays that mimic the antigen presenting
cell surface during t cell activation .
the assessment of activation
related events revealed the requirement of a minimal density of 90140
stimulating major hist... | |
in fact , relevant and required information should be correctly identified , and then the process begins .
rapid increase in information and specialization of sciences has made the accessibility to appropriate information difficult .
it is essential to identify the information needs of each individual or society co... | background : patients , as one of the most prominent groups requiring health - based information , encounter numerous problems in order to obtain these pieces of information and apply them .
the aim of this study was to determine the information - seeking behavior of cardiovascular patients who were hospitalized in i... |
according to the world health organization , an adverse drug reaction ( adr ) may be defined as a response to a drug which is noxious and unintended , and which occurs at doses normally used or tested in man for the prophylaxis , diagnosis , or therapy of disease , or for the modification of physiological function .
... | fixed - drug eruption ( fde ) is an unusual and rare adverse drug reaction .
this type of reaction is actually a delayed type of hypersensitivity reaction that occurs as lesions recurring at the same skin site due to repeated intake of an offending drug .
here is a case report of a 58-year - old male patient who de... |
methylene dianiline ( ddm ) is a chemical intermediate in the production of isocyanates and other industrial chemicals , and it is hepatotoxic in humans . the acute hepatotoxicity of orally administered ddm was characterized in rats .
rats receiving ddm ( 25 - 225 mg / kg , per os ) demonstrated a dose - dependent el... | |
temporomandibular joint ( tmj ) response to mandibular advancement surgery is sporadically
associated to arthralgia ( pain ) , functional limitations , condylar resorption and
skeletal relapse . when the mandible is advanced and fixed , the adjacent tissues are
stretched and tend to displace the distal segment ba... | objectivein order to understand the conflicting information on temporomandibular joint
( tmj ) pathophysiologic responses after mandibular advancement surgery , an overview
of the literature was proposed with a focus on certain risk factors .
methodsa literature search was carried out in the cochrane , pubmed , s... |
in the last decade , a rapid rise in the demand for natural health products has become evident .
this prominent trend stems from increasing awareness of the potential for significant adverse effects caused by pharmacologic interventions , along with a growing interest in preventive medicine strategies .
a group of ... | some cruciferous plants may serve as preventive treatments for several medical conditions ; our objective was to systematically investigate their safety in humans .
four electronic databases were searched , and , of 10,831 references identified , 50 were included .
data were extracted by two independent reviewers ,... |
ewing 's sarcoma is a rare mesenchymal malignancy which is histologically similar to primitive neuroectodermal tumors ( pnets ) .
the extraosseous / intracranial form of ewing 's sarcoma tumors is particularly rare , and often presents in the pediatric population .
particular care must be taken to distinguish the t... | the ewing sarcoma family of tumors comprises a rare class of cancers of mesenchymal origin .
cases of ewing 's sarcoma in the central nervous system specifically , intracranial ewing 's are extremely rare . almost all reported cases have occurred in children . however , this rare presentation can also occur in the ... |
estimates of health - state utility ( hsu ) are an integral part of an analysis of the cost - effectiveness of a new therapy .
utility values are typically sourced either from a clinical study or from the published literature , using a validated generic preference - based multiattribute utility instrument , such as e... | objectivesin the absence of euroqol 5d data , mapping algorithms can be used to predict health - state utility values ( hsuvs ) for use in economic evaluation . in a placebo - controlled phase ii study of olaparib maintenance therapy ( nct00753545 ) , health - related quality of life
was measured using the functional... |
petrochemical plastics have been developed into a major industry and are resistant to natural and chemical breakdowns ( 1 ) .
alternatively , bioplastics are polyesters synthesized by bacteria under unbalanced growth conditions ( 2 ) .
poly hydroxyalkanoate ( pha ) , the most known source of bioplastics , is a pote... | background : poly 3-hydroxybutyrate ( phb ) , a class of poly hydroxyalkanoates ( phas ) , is a group of bacterial storage polymers , produced by various microorganisms in response to nutrient limitation .
phas are biodegradable polymers which could be a good substitute for current petrochemical plastics .
phb has ... |
psoriatic arthritis ( psa ) is a multifactorial chronic inflammatory joint disease associated with psoriasis , usually with no detectable rheumatoid factor ( rf ) , and belongs to the seronegative subgroup of spondyloarthritis .
clinically , patients with psa present with different manifestations such as mild mono-/o... | objective . to analyse levels of s100a8/s100a9 ( calprotectin ) and selected cytokines , in blood , in patients with psoriatic arthritis ( psa ) . methods .
sixty - five patients with psa were examined for clinical manifestations and laboratory measurements of s - calprotectin , esr , hs - crp , and selected cytokine... |
fungi of this genus have been isolated from a wide range of hosts such as humans , woody plants , and the larvae of bark beetles , but only some species of this genus have been reported as pathogens of humans [ 2 , 3 ] .
presently , the phaeoacremonium genus , formerly known as phialophora , includes more than 20 spe... | phaeohyphomycosis is a subcutaneous infection caused by dark pigmented fungi , including fungi of the species phaeoacremonium , alternaria , exophiala , and pyrenochaeta . in august 2005
, a 54-yr - old man who had received a renal transplant 5 yr ago was admitted to our hospital with a subcutaneous mass on the third... |
in recent years , evidence has accumulated that breast arterial calcifications ( bac ) noted on mammography are indicators of coexisting cardiovascular disease .
cardiovascular diseases are a significant cause of morbidity and mortality in women over 50 years and the feasibility of early diagnosis is important .
we... | objectives : the purpose of this study is to establish a database including prevalence and degree of breast arterial calcifications ( bac ) in our population of women presenting for mammography.materials and methods : the mammograms of 1786 women over the age of 40 years were examined for the presence and degree of bac... |
microvascular complications are major contributors to morbidity , mortality and costs of both non - insulin - dependent ( niddm ) and insulin - dependent diabetes mellitus ( iddm ) .
damage of the small vessels in the kidney can lead to end - stage renal disease , structural alterations of the smaller vessels that su... | abstractthe aim of this article is to briefly review available data regarding changes in the structure of microvessels observed in patients with diabetes mellitus , and possible correction by effective treatment .
the development of structural changes in the systemic vasculature is the end result of established hyper... |
the study population consisted of 30 subjects belonging to both sexes and all the subjects selected were from the outpatient clinics of the department of periodontics , in jkkn dental college .
the following parameters were evaluated for the subjects : plaque index ( pi ) , the gingival index ( gi ) , probing depth (... | aim and background : a disintegrin and metalloproteinase 8 ( adam8 ) is a marker belonging to the class of adam family of metalloproteinase which is found to be involved in inflammation and bone resorption in periodontal disease by acting as osteoclast stimulating factor . in several systemic inflammatory diseases , el... |
bacterial strains : a total of 123 strains of s. aureus
isolated in 2007 and 2008 from subclinical bovine mastitis ( scm ) milk samples were included
in this study . the bacterial strains were identified as s. aureus by
colonial and microscopic morphology examination and tube tests for coagulase and catalase
ac... | abstractthe aim of this study was to analyze the resistance of staphylococcus
aureus isolates from bovine mastitis in the eastern part of poland to a set of
20 antibiotics and three alternative agents : lysostaphin , nisin and polymyxin b.
eighty - six out of 123 examined isolates were susceptible to all 20 teste... |
esophageal carcinoma is one of the six most common malignant tumors in the world and is associated with significant morbidity and mortality . with a high incidence in the provinces of hebei , henan , and guangdong , china ,
both genetic and environmental factors have been implicated in the development of esophageal c... | tumor necrosis factor receptor 1 ( tnfr1 ) is a membrane receptor able to bind tnf- or tnf-. tnfr1 can suppress apoptosis by activating the nf-b or jnk / sapk signal transduction pathway , or it can induce apoptosis through a series of caspase cascade reactions ; the particular effect may depend on the cell line . in t... |
it is important in conveying the daily cycle of light and darkness to the body , thus regulating circadian rhythms .
in addition to its regulatory role , melatonin has antioxidative capacity , immunomodulatory potency , and also appears to be protective against certain types of cancers .
type 1 diabetes mellitus ( ... | objective : melatonin is an indolamine hormone , synthesized from tryptophan in the pineal gland primarily .
melatonin exerts both antioxidative and immunoregulatory roles but little is known about melatonin secretion in patients with type 1 diabetes mellitus ( t1 dm ) .
the aim of this study was to measure serum m... |
nevus lipomatosus cutaneous superficialis ( nlcs ) is a rare benign hamartomatous condition , which usually presents at birth or manifests in the first two decades of life .
the classical presentation is with multiple painless soft pedunculated , yellowish cerebriform masses commonly located on the pelvic and gluteal... | nevus lipomatosus cutaneous superficialis ( nlcs ) is a benign dermatosis , histologically characterized by the presence of mature ectopic adipocytes in the dermis .
we hereby report a case of a 10-year - old boy who presented with multiple huge swellings on the scapular regions and lower back .
the lesions were su... |
in south africa , the global epicenter of both tuberculosis ( tb ) and human immunodeficiency virus ( hiv ) , the menacing convergence of these diseases : one viral and one bacterial , one emergent , and one ancient , presents a near insurmountable challenge to health , social , economic , and developmental welfare .
... | background . expanded hiv surveillance in tb patients forms part of the world health organization framework for strategic collaborative activity .
surveillance helps understand the epidemiology of the local dual epidemic and enables design of a tailored response to these challenges .
methods .
we conducted an obs... |
traditional therapy for uterine hyperplasia , carcinoma , or sarcoma includes total abdominal hysterectomy ( tah ) with salpingo - oophorectomy , and when pathologic stage is higher than ib or tumor grade is 3 , lymph node sampling is performed . in 1993 ,
laparoscopic - assisted vaginal hysterectomy ( lavh ) with in... | objective : retrospective analysis of surgico - pathologic data comparing total laparoscopic hysterectomy ( tlh ) with total abdominal hysterectomy ( tah ) patients with uterine neoplasiamethods : we conducted a chart abstraction of all patients undergoing hysterectomy for uterine neoplasia from september 1996 to novem... |
kathleen canning has used the german factory to locate her work on the dichotomy between experience and discourse to contend that the study of
when canning s theoretical framework was applied to medical records captured in the nineteenth - century irish convict prison , this research found that the experience of in... | this article focuses on the function of the convict prison infirmary and views it as a site of arbitration , resistance and contested power. in accordance with the rules and regulations periods of incarceration in convict prisons began and ended with an obligatory medical examination .
while the primary function of ... |
isolated iliac artery aneurysms are extremely rare , representing only 0.03% of a series of 26 251 autopsy patients , mostly associated with atherosclerosis and with other aetiological factors including trauma and infection .
presentation is variable including incidental findings during surgery , abdominal or rectal... | isolated iliac artery aneurysms are extremely rare .
gluteal artery aneurysms are also rare , more commonly affecting the superior gluteal artery in association with penetrating trauma , with those of the inferior gluteal artery usually associated with pelvic fractures .
we discuss a diagnostically challenging pres... |
patients and ethics - this study enrolled 200 patients with chronic hcv
infection ( 72 males , aged 54.2 11.1 years ) and 100 healthy individuals ( 34 males , aged
51.1 9.7 years ) living in rj between 2013 - 2014 .
healthy individuals and patients with
chronic hcv infection on antiviral therapy were prospect... | inosine triphosphatase ( itpa ) single nucleotide polymorphisms ( snps ) are strongly
associated with protection against ribavirin ( rbv)-induced anaemia in european ,
american and asian patients ; however , there is a paucity of data for brazilian
patients .
the aim of this study was to evaluate the itpa snp (... |
drug delivery systems ( ddss ) are useful for reducing drug side effects and maximizing drug action .
the design of drug carriers for dds is the most important activity in this area .
the advent of molecular biology studies has enabled the identification of many disease - causing proteins . because some of these ar... | hydroxyapatite ( ha ) is a precursor of bone and has been studied as a biomaterial .
we attempted ha to apply to protein delivery systems . in this study ,
the association and dissociation properties of two types of bioactive proteins , cytochrom c and insulin , to ha were investigated .
cytochrom c was less asso... |
a 53 years - old male visited to our clinic because of cognitive impairment for two years ago .
the patient graduated from university , had worked as an office worker and recently retired .
his wife described that , the patient s memory and ability of judgment had been impaired for 2 years , and his verbal output h... | multiple system atrophy ( msa ) is a sporadic , adult - onset disease characterized by progressive degeneration of nervous systems including cerebellar , pyramidal , extrapyramidal , and autonomic system .
although a few recent studies reported that cognitive impairments could occur in patients with msa , prominent d... |
in our simulations we use the mnpbem toolbox , which is based on a boundary element method
approach for the solution of maxwell s equations , and its eels extension .
we start with
a triangle with rounded edges , as shown at the left top of figure 1b and extract the triangle contour rtri( ) in polar coordinates .... | we
morph a silver nanodisk into a nanotriangle by producing a series
of nanoparticles with electron beam lithography . using electron energy
loss spectroscopy ( eels ) , we map out the plasmonic eigenmodes and
trace the evolution of edge and film modes during morphing . our results
suggest that disk modes , c... |
observational studies and clinical trials have shown that adherence to the dietary approaches to stop hypertension ( dash ) diet is associated with improved cardiovascular health and cardiovascular disease ( cvd ) risk in adults and youth .
youth with diabetes are at an increased risk of developing cvd . in a cross -... | youth with diabetes are at an increased risk of cardiovascular disease ( cvd ) .
adherence to the dietary approaches to stop hypertension ( dash ) diet has been shown to improve cvd risk . in this study
, we evaluated whether changes in diet quality as characterized by dash are associated with changes in cvd risk f... |
the international agency for cancer research ( iarc ) has shown a low incidence of prostate cancer in east asian countries as compared to western counterparts although its incidence in india is rising as well .
comprehensive search for risk factors that contribute in the initiation and progression of prostate cancer ... | aims : the association of central obesity , hyperinsulinemia , and dyslipidemia with higher grade advanced prostate cancer as determined by gleason grading is not well understood .
we evaluated the effect of central obesity waist hip ratio ( whr 0.9 ) and biochemical parameters associated with central obesity on gle... |
type 2 diabetes mellitus ( t2 dm ) is a chronic , progressive disease that requires continuing and
demanding medical care in the attempt to reduce the risk of long - term complications.1 genetic and environmental factors concur in sustaining
the core pathogenetic mechanisms of diabetes , ie , insulin resistance and... | backgrounddipeptidyl peptidase-4 ( dpp-4 ) inhibitors are novel classified oral anti - diabetic drugs for the
treatment of type 2 diabetes mellitus ( t2 dm ) that provide important reduction in glycated
hemoglobin , with a low risk for hypoglycemia and no weight gain . in t2
dm patients with reduced renal
funct... |
as spinal surgery techniques and instrumentation devices develop , the demand for minimally invasive spinal fixation ( misf ) grows .
misf has many advantages , including less blood loss , shorter length of hospital stay , lower rates of infection , and better relief of postoperative pain than traditional open surger... | study design retrospective comparative study .
objective to evaluate the accuracy of percutaneous pedicle screw ( pps ) placement and intraoperative imaging time using dual fluoroscopy units and their differences between surgeons with more versus less experience .
methods one hundred sixty - one patients who und... |
little is understood about this condition 's mechanism , exacerbating factor , and definite treatment .
hyperhidrosis generally occurs in the axillae , the palms , plantar surface of the feet , and the face .
it is estimated to affect 0.6 to 1.0% of the population , generally young adults .
the principal characte... | backgroundvideo - assisted thoracic sympathicotomy plays an important for the treatment of essential hyperhidrosis .
patients are usually satisfied with the surgical outcome at the early post - operative period , but suffer recurrence and compensatory sweating in the late post - operative period .
there are many sy... |
the generation of reactive oxygen species ( ros ) and subsequent oxidative modification of biomolecules , such as lipids , proteins , and nucleic acids , are inevitable in aerobic organisms .
an excessive amount of ros has been implicated in a variety of pathological events such as atherosclerosis , ischemia - reperf... | although lipid peroxidation products have been implicated in oxidative stress - related diseases , pretreatment of cells with such compounds at sublethal concentrations shows significant cytoprotective effects against forthcoming oxidative stress . the adaptive response induced by 4-hydroxynonenal ( hne )
is critical... |
the us centers for disease control and prevention ( cdc ; atlanta , ga ) reported 1651 cases of human foodborne listeriosis from listeria monocytogenes ( lm ) which occurred from 2009 to 2011 , with a case - fatality rate of 21% .
nevertheless , the us department of agriculture food safety and inspection service ( ... | this study evaluated the efficacy of organic acids applied singly or in combination as postlethality dips to sliced uncured turkey deli loaves to inhibit the growth of listeria monocytogenes ( lm ) scott a. treatments consisted of sodium lactate ( sl ; 3.6% ) , potassium lactate ( pl ; 3.6% ) , sodium citrate ( sc ; 0.... |
since its invention in 1973 , x - ray computed tomography ( ct ) has revolutionized medical imaging and become a cornerstone of modern radiology . improving resolution and reducing dose are two critical factors in biomedical applications and remain the focuses of ct research . with the emergence of multislice spiral
... | although x - ray imaging is widely used in biomedical applications , biological soft tissues have small density changes , leading to low contrast resolution for attenuation - based x - ray imaging . over the past years
, x - ray small - angle scattering was studied as a new contrast mechanism to enhance subtle struct... |
pulmonary arterial hypertension ( pah ) is defined by a resting mean pulmonary arterial
pressure over 25 mmhg , confirmed by right heart catheterization1 , 2 .
pah is a rare and
progressive disorder of the pulmonary circulation that leads to deterioration in
cardiopulmonary function , and , ultimately , to righ... | [ purpose ] this study investigated functional capacity , physical activity , and respiratory
and peripheral muscle strength in different functional classes of pulmonary arterial
hypertension ( pah ) compared with healthy subjects .
[ subjects and methods ] this study
included 31 patients with class ii ( n = 16... |
chronic kidney disease ( ckd ) is a worldwide public health problem that affects approximately 6% of the uk adult population and is associated with a high prevalence of cardiovascular disease and large economic burden .
anaemia occurs early during the course of ckd and progressively increases as a result of iron and ... | the national service framework advocates correction of anaemia in patients with chronic kidney disease ( ckd ) .
oral iron is insufficient , while intravenous ( iv ) supplementation replenishes and maintains iron stores .
previously , effective delivery of iron therapy using available parenteral preparations has be... |
skeletal and dentofacial discrepancies may adversely influence the quality of life ( qol ) of patients through affecting their facial appearance , oral function or both [ 1 - 3 ] .
patients with malocclusion , especially those severe cases that need surgical correction , are proved to have lower oral health - related... | abstractobjectivesthis study was designed to assess the relationship between postsurgical cephalometric changes and quality of life and satisfaction after orthognathic surgery.material and methodssample size consisted of 30 patients with class iii and 25 patients with class ii malocclusion treated with bilateral sagitt... |
urinary retention ( ur ) defined as inability to achieve complete bladder emptying by voluntary micturition , resulting in a high postvoid urinary residual volume and categorized as acute ur or chronic ur .
incidence of ur in women is estimated at 0.07 per 1,000 inhabitants each year and relatively uncommon compared ... | purposewe aimed to analyze the characteristics of urinary retention ( ur ) in female inpatients managed with medical treatments.materials and methodswe retrospectively analyzed the medical records of female inpatients referred to the department of urology for ur at our institution from january 2009 , to december 2014 .... |
in malaria high - transmission areas , some population groups are at considerably higher risk of infection with plasmodium falciparum and development of malaria morbidity or mortality than others .
malaria contributes significantly to perinatal disease burden in terms of pregnancy loss , prematurity due to preterm la... | malaria congenital infection constitutes a major risk in malaria endemic areas . in this study , we report the prevalence of transplacental malaria in burkina faso . in labour and delivery units ,
thick and thin blood films were made from maternal , placental , and umbilical cord blood to determine malaria infection ... |
adherens junctions ( ajs ) are cell - cell adhesion sites where calcium - dependent cadherin receptors bind with their extracellular domains to cadherins on opposing cells and with their cytoplasmic tails connect via adaptors to filamentous actin [ 1 , 2 ] . by essentially providing a physical link between the actin ... | adherens junctions connect the actin cytoskeleton of neighboring cells through transmembrane cadherin receptors and a network of adaptor proteins .
the interactions between these adaptors and cadherin as well as the activity of actin regulators localized to adherens junctions are tightly controlled to facilitate cell... |
as a part of commonly known traditional chinese medicinal plants , radix polygalae ( rp ) can be obtained from polygala tenuifolia willd . and p. sibirica l. , which are listed in the chinese pharmacopoeia ( 2010 ) ; rp elicits sedative , antipsychotic , expectorant , and anti - inflammatory effects . high consumption ... | radix polygalae , the dried roots of polygala tenuifolia and p. sibirica , is one of the most well - known traditional chinese medicinal plants . radix polygalae contains various saponins , xanthones , and oligosaccharide esters and these compounds are responsible for several pharmacological properties . to provide bas... |
histoplasmosis is caused by the dimorphic fungus histoplasma capsulatum ( h. capsulatum ) , the clinical spectrum of which ranges from transient pulmonary infections to disseminated disease .
the infection is acquired with the inhalation of spores of h. capsulatum found in soils contaminated by bird and bat excreta .... | disseminated histoplasmosis is caused by the dimorphic fungus histoplasma capsulatum ( h. capsulatum ) .
the early clinical manifestations are nonspecific , often lead to diagnostic difficulty , and is misdiagnosed as tuberculosis and seen usually in immunosuppressed states .
fine needle aspiration cytology ( fnac ... |
topical -blocker solution is a useful treatment for glaucoma , but it may be an unrecognized and neglected reason for bradycardia for frail geriatric patients .
levobunolol hydrochloride solution , a commonly prescribed medication for patients with glaucoma , contains 5 mg levobunolol hydrochloride / ml .
rarely , ... | an 88-year - old man was admitted with fatigue , dizziness , and heart palpitations .
both the electrocardiogram and holter confirmed the existence of sinus bradycardia and sinus arrest .
one hour prior to the onset of symptoms , he received levobunolol hydrochloride solution topically .
the levobunolol hydrochlo... |
epstein barr virus ( ebv ) is the cause of mononucleosis that is generally benign disease in children with classical features of fatigue , pharyngitis , and lymphadenopathy .
ebv infections have led to subclinical infection , infectious mononucleosis , and associations with malignancies and central nervous system ( ... | infectious mononucleosis due to epstein barr virus ( ebv ) is a usually benign systemic viral illness common in children .
many studies described nervous system manifestations of infectious mononucleosis with a wide spectrum of neurologic deficits .
neurologic complications of ebv are seen in both acute and reacti... |
hepatitis e virus ( hev ) , the sole member of the family hepeviridae , is an under - recognized cause of acute hepatitis . in resource - poor areas of developing countries , where the virus is endemic
, hev is responsible for large water - borne outbreaks of significant morbidity . in non - endemic areas , where san... | background : previous studies have documented a high prevalence of hepatitis e among patients undergoing maintenance hemodialysis .
available studies reporting on the seroprevalence of hepatitis e in hemodialysis patients in iran , an endemic region for the disease , are sparse.objectives:the present study aimed to d... |
a 35-year - old female reported with complaints of painful ulcers in the mouth , bleeding lips , rashes throughout the body , and high fever ( 39c ) of 4 days duration .
her past medical history revealed that she was suffering from seizures for past 4 years and was on medication ( valproate 600 mg / day ) for the sam... | lamotrigine and valproic acid are well - tolerated anticonvulsants , but frequently associated with severe cutaneous reactions , such as the stevens johnson syndrome ( sjs ) and toxic epidermal necrolysis , when used in combination .
we report a case of sjs likely induced by the use of a lamotrigine and valproic aci... |
although immuno - modulating type-1 interferons and glatiramer acetate reduce active cns inflammatory lesions , clinical severity and attack frequency in relapsing remitting ms , they are less efficacious in progressive disease . the immunosuppressive agent , mitoxantrone is presently approved for treating progressive ... | backgroundligands of the peroxisome proliferator - activated receptor - gamma ( ppar ) induce apoptosis in activated t - lymphocytes and exert anti - inflammatory effects in glial cells .
preclinical studies have shown that the thiazolidinedione pioglitazone , an fda - approved ppar agonist used to treat type 2 diabe... |
evidence - based clinical practice requires that practitioners consider the best available evidence in support of potential clinical decisions .
the highest category of evidence includes randomized controlled trials . with the increasing emphasis on evidence - based medicine ,
the urology literature has seen a rapi... | objectives : with the increasing emphasis on evidence - based medicine , the urology literature has seen a rapid growth in the number of high - quality randomized controlled trials along with increased statistical rigor in the reporting of study results .
p - values , ci , and number needed to treat ( nnt ) are becom... |
on july 2004 , a previously healthy 44-year - old man who lived in gabon was admitted to the outpatient clinic of the university hospital in udine , italy , with a 6-month history of recurrent fever , headache , fatigue , weight loss , leg paresthesias , gait difficulties , and daytime somnolence .
he had been living... | african trypanosomiasis caused by trypanosoma brucei gambiense has not been reported in italy .
we report 2 cases diagnosed in the summer of 2004 .
theses cases suggest an increased risk for expatriates working in trypanosomiasis - endemic countries .
travel medicine clinics should be increasingly aware of this p... |
woscops randomized 6,595 men ages 45 to 64 years with moderate hypercholesterolemia ( ldl cholesterol concentrations 152 to 228 mg / dl ) and no prior history of myocardial infarction to receive placebo or pravastatin 40 mg / day .
plasma was obtained before randomization and at 1 year , and was stored at 80c . for t... | backgroundcardiac troponin is an independent predictor of cardiovascular mortality in individuals without symptoms or signs of cardiovascular disease .
the mechanisms for this association are uncertain , and a role for troponin testing in the prevention of coronary heart disease has yet to be established.objectivesth... |
with improved outcomes of postliver transplantation , a large number of pediatric liver transplant recipients are reaching adulthood .
the posttransplantation five - year graft / survival rate for pediatric liver transplant recipients currently ranges from 67% to 82% [ 2 , 3 ] .
therefore , the need to prepare pedi... | the transition from pediatric to adult care is a critical time when children with chronic illness sustain high morbidity and mortality .
transition services need to be focused on the adolescents ' needs , which may differ from those perceived by healthcare providers . in this study ,
a survey of 31 patients with ch... |
glaucoma is an optic neuropathy characterized by progressive degeneration of retinal ganglion cells ( rgcs ) and their axons , resulting in changes in the appearance of the optic disc and visual field loss .
although glaucoma is a multifactorial disease , elevated intraocular pressure ( iop ) remains its major known ... | the aim of this study was to evaluate the relationship between glucose levels and intraocular pressure ( iop ) fluctuation in diabetic and nondiabetic patients .
seventeen nondiabetic and 20 diabetic subjects underwent a complete ophthalmic examination , capillary glucose testing , and applanation tonometry in two di... |
breast cancer is one of the most common cancers among females worldwide and the first malignancy affecting iranian women ( 1 - 4 ) .
it is assumed that behavior , prognosis , and treatment response are very different in this non - homogenous disease ( 5 ) . despite all efforts in early diagnosis , treatment and bioma... | background : patients with early stage breast cancer with same treatment strategy can have markedly different outcomes . human epidermal growth factor receptor 2 ( her2/nue ) gene amplification or the subsequent overexpression of protein has been proved to be associated with patient 's outcome and response to anthracyc... |
the economic impact depressive symptoms have on work is significant in most countries ,
including japan1 , 2 . okumura and higuchi estimated that the annual cost of workplace
absenteeism and presenteeism in japan due to depression2 amounted to us$6.9 billion . in the united states , depression costs
$ 44 billion ... | we aimed to determine the economic impact of absenteeism and presenteeism from five
conditions potentially comorbid with depressive symptoms back or neck disorders ,
depression , anxiety , or emotional disorders , chronic headaches , stomach or bowel
disorders , and insomnia among japanese workers aged 1859 yr ... |
to achieve effective muscle hypertrophy with less exercise , a training method involving application of pressure to the target muscle , named kaatsu training , was developed , and is now used in rehabilitation programs for heart disease patients in some hospitals . in this method ,
the muscles are tightly wrapped dur... | abstractkaatsu training is an exercise method involving the application of pressure to the target muscle , and is being increasingly used in rehabilitation programs for heart disease patients in some hospitals .
this method restricts blood flow to the muscles during exercise , and the resultant hypoxia effectively ca... |
as energy demand of these muscle tissues varies by several orders of magnitude , energy metabolism has to be tightly regulated in order to meet varying energy requirement . in this review
, we shall first describe the physiology of energy metabolism in muscle , and then deal with different myopathies caused by inborn... | inherited neuromuscular disorders affect approximately one in 3,500 children .
structural muscular defects are most common ; however functional impairment of skeletal and cardiac muscle in both children and adults may be caused by inborn errors of energy metabolism as well .
patients suffering from metabolic myopat... |
a or 1 raw milk is an spc value less than 1.0 10cfu / ml .
cooling of raw milk to less than 6c ( typically 3 to 4c in the farm tank following milking ) , followed by storage at temperatures below 6c during transportation to the dairy plant , ensures the quality of raw milk . because milk is a highly suitable growth ... | psychrotrophic bacteria in raw milk are most well known for their spoilage potential and cause significant economic losses in the dairy industry . despite their ability to produce several exoenzyme types at low temperatures , psychrotrophs that dominate the microflora at the time of spoilage are generally considered be... |
an abnormal extraosseous tracer uptake may be encountered in many organs during the technetium-99 m methylene diphosphonate ( tc-99 m mdp ) bone scan .
though such extraosseous uptake in the brain is rare , it may occur due to malignancy , calcification or infarct .
few instances of diagnosis of acute infarcts in t... | technetium-99 m methylene diphosphonate scintigraphy is usually performed to assess bone lesions , especially skeletal metastases in patients with a history of malignancy .
however , it is important to recognize some specific conditions with a unique pattern of tracer uptake , especially in extraosseous locations as ... |
it has been previously thought that dementia occurred in 20%30% of parkinson disease ( pd ) patients , usually at the later stage of their illness .
however , recent long term epidemiological studies reported the prevalence rate of dementia in pd closer to 50% ( hely et al 2005 ) .
others have reported that some fo... | we performed an analysis of prospectively - acquired cross sectional data on 106 parkinson disease ( pd ) patients who underwent comprehensive neuropsychological testing and the unified parkinson disease rating scale ( updrs ) motor scale .
a significant correlation between the updrs motor and neuropsychological test... |
we describe the facile synthesis
of several two - dimensional covalent organic
frameworks ( 2d cofs ) as films by vapor - assisted conversion at room
temperature .
high - quality films of benzodithiophene - containing bdt - cof
and cof-5 with tunable thickness were synthesized under different
conditions on... | |
locally recurrent prostate cancer following external beam radiotherapy ( ebrt ) is a therapeutic dilemma .
viable residual carcinoma has been estimated to occur in 10 - 54% of patients two or more years following ebrt [ 13 ] .
patients diagnosed with locally persistent disease often seek a second local treatment to... | purposeto report outcomes on 5 patients treated with salvage partial low - dose - rate ( ldr ) 125-iodine ( 125i ) permanent prostate seed brachytherapy ( bt ) for biopsy - proven locally persistent prostate cancer , following failure of dose - escalated external beam radiotherapy ( ebrt).material and methodsa retrospe... |
fabry disease ( fd ) is a x chromosome - linked inherited lysosomal storage disorder , due to partial or complete deficient activity of the enzyme -galactosidase a caused by different x - chromosomal recessive mutations in the galactosidase gene . the decrease or absence of enzyme activity results in progressive accumu... | fabry disease ( fd ) is an x - linked lysosomal storage disorder characterized by a deficient activity of the enzyme -galactosidase a , resulting in a vasculopathic involvement of various organ systems , e.g. cerebral structures .
marked cerebral vasculopathy with subsequent white matter lesions ( wml ) are a frequen... |
the current west africa epidemic of ebola virus disease ( evd ) , which began from guinea in december 2013 , has been the longest and deadliest ebola outbreak to date .
ebola 's method of transmission makes it amenable to containment by coordinated efforts from the public health community worldwide .
those efforts ... | background : the current west africa epidemic of ebola virus disease ( evd ) , which began from guinea in december 2013 , has been the longest and deadliest ebola outbreak to date . with the propagation of the internet
, public health officials must now compete with other official and unofficial sources of informatio... |
dental implants are used widely in clinical dentistry today to restore partial
or complete edentulism .
the longevity of the implants and
the supported restoration depend on a great degree of the careful evaluation of
clinical parameters , the proper design of the treatment plan and its precise execution
.
... | abstractbackgroundthe hard and soft tissue deficiency is a limiting factor for the
prosthetic restoration and any surgical attempt to correct the anatomic
foundation needs to be precisely executed for optimal results .
the purpose of this paper is to describe the clinical
steps that are needed to confirm the tr... |
globally , oral cancer has emerged as an important cause of global public health concern .
world health organization ( who ) has estimated that the incidence of oral cancer varies from1 to 10 cases per 100,000 people in most of the countries .
further , it has been realized that more than 50% of oral cancer patient... | backgroundoral cancer has emerged as a significant cause of global public health concern .
if a cancerous lesion is diagnosed in primary stages , the survival rate would be higher .
thus , the aim of this study was to evaluate knowledge , attitude and practice of general dentist regarding oral cancer in sari , iran... |
a normal parathyroid gland ( pg ) is not visualized on ultrasonography ; an enlarged one , however , appears as hypoechoic ( compared to that of the normal thyroid tissue ) tear - drop shaped nodule separated from thyroid gland by an intervening echogenic posterior capsule of thyroid .
the uniform echostructure of th... | the typical sonomorphology of homogeneously hypoechoic texture of an enlarged parathyroid gland ( pg ) is a reflection of uniform arrangement of the parathormone - producing chief cells .
a variable cellular arrangement , hemorrhage , fibrosis , and adipocytes cause heterogeneous appearance .
we describe a case of ... |
vascular anomalies are congenital lesions of abnormal vascular development . previously referred to as vascular birthmarks
, vascular anomalies are now classified based on a system developed in 1982 by mulliken and glowacki that considers histology , biological behavior , and clinical presentation of these entities .... | vascular anomalies are a heterogeneous group of congenital blood vessel disorders more typically referred to as birthmarks .
subcategorized into vascular tumors and malformations , each anomaly is characterized by specific morphology , pathophysiology , clinical behavior , and management approach .
hemangiomas are ... |
they are completely unrelated in sequence to the known cation channels or to other known anion - conducting channels , including the cystic fibrosis transmembrane conductance regulator ( cftr ) chloride channels , porins , and -aminobutyric acid ( gaba ) receptors .
the family is evolutionarily ancient , with members... | chloride - conducting ion channels of the clc family are emerging as critical contributors to a host of biological processes .
these polytopic membrane proteins form aqueous pathways through which anions are selectively allowed to pass down their concentration gradients .
the clcs are found in nearly all organisms ... |
the participants of this study included 56 ( 21 men ) non- clinical participants , 30 ( 11 men ) patients with general anxiety disorder and 25 ( 4 men ) with obsessive compulsive disorder .
the total sample consisted of 36 men and 75 women , with the mean age of 31.89 ( sd = 8.13 ) .
all clinical participants were ... | objectiveattention is an important factor in information processing ; obsessive- compulsive disorder ( ocd ) and generalized anxiety disorder ( gad ) are two main emotional disorders with a chronic course .
this research examined the relationship among attentional control and intrusive thoughts ( worry , rumination a... |
the online version of this article ( doi:10.1007/s00125 - 010 - 1874-x ) contains supplementary material , which is available to authorised users .
it is now commonly accepted that depressive symptoms and major depressive disorder ( mdd ) are twice as prevalent in individuals with type 2 diabetes [ 1 , 2 ] . moreover... | aims / hypothesisan earlier meta - analysis showed that diabetes is a risk factor for the development and/or recurrence of depression . yet whether this risk is different for studies using questionnaires than for those relying on diagnostic criteria for depression has not been examined .
this study examined the assoc... |
a 60-year - old hypertensive man with no history of head trauma presented with sudden headache and vomiting .
he was admitted to our department 5 days after the on - set of the symptoms .
his past neurological history was unrevealing and there was no history of head trauma , blood clot disturbances , or anticoagula... | subdural hematoma ( sdh ) caused by rupture of a cerebral aneurysm is rare and is usually associated with delayed diagnosis and treatment .
we present a patient of a posterior cerebral artery aneurysm presenting as subacute sdh .
the incidence , mechanisms and treatment of this condition are discussed . |
the advent of p2y12 inhibitors with antiplatelet effects has extended the use of the drug - eluting stent ( des ) for occlusive coronary artery disease . dual antiplatelet therapy ( dapt ) with aspirin and clopidogrel had been considered the standard treatment in patients with acute coronary syndromes ( acss ) undergoi... | background and objectiveswe evaluated the effectiveness of genotype- and phenotype - directed individualization of p2y12 inhibitors to decrease high on - treatment platelet reactivity ( hopr).subjects and methodssixty - five patients undergoing percutaneous coronary intervention for non - st elevation acute coronary sy... |
an evaluation of the ovarian reserve is essential for the infertility work up and treatment .
advanced female age is associated with diminished ovarian reserve , but the age by itself does not accurately predict the ovarian reserve ( 1 ) .
the commonly used tests for ovarian reserve are basal follicle stimulating h... | serum anti - mllerian hormone ( amh ) levels are regarded as an age - specific marker for predicting the ovarian reserve in women of reproductive age .
some studies have shown that the luteinizing hormone ( lh)/follicle stimulating hormone ( fsh ) ratio can be used as a predictor of ovarian reserve .
the purpose of... |
breast cancer is the most common cancer affecting women as it accounts for over one - third of all cancers reported in this population .
although the cure rate is high , the sheer number of new cases detected every year means that the mortality rate associated with this cancer remains high .
advances in diagnostic ... | objectives . the aim of this prospective phase ii study is to evaluate the treatment of early - stage breast cancer ( t1 n0 ) with intraoperative electron radiation therapy ( ioert ) in terms of local control , early complications , and cosmesis .
patients and methods . from february 2010 to february 2012 , 200 patie... |
current data of the federal statistic office ( statistisches bundesamt ) indicate that 19 percent of the german population are considered having a migration background
15.3 million people ) , including both germans and foreign nationals . in some cities , like berlin , hamburg or frankfurt ( main ) , migrants consti... | one of the main challenges for teaching programs on immigration , ethnic diversity and health is to transform the commonplace notion of culture into a helpful tool for medical training and practice .
this paper presents the teaching approach of an interdisciplinary course on
migrants health established at the un... |
the doetinchem cohort study ( dcs ) ( 11 ) is an ongoing prospective study , initially carried out in a random general population sample of 7,769 men and women aged 2059 years ( 19871991 ) .
the aim of the doetinchem cohort study was to study the impact of ( changes in ) lifestyle factors and biological risk factors ... | objectiveto test the hypothesis that type 2 diabetes is associated with greater decline in cognitive function in middle - aged individuals.research design and methodsin the dutch prospective doetinchem cohort study , cognitive functioning was measured twice within a 5-year time interval in 2,613 men and women .
parti... |
public healthcare resources are limited all over the world ; hence , encouraging the use of evidencebased and transparent decisionmaking processes to inform the allocation of scarce resources is essential at both global and national levels .
multidisciplinary tools and methods need to be established and implemented i... | abstractthe opportunity cost of inappropriate health policy decisions is greater in central and eastern european ( cee ) compared with western european ( we ) countries because of poorer population health and more limited healthcare resources .
application of health technology assessment ( hta ) prior to healthcare f... |
the extremely high predictability of endodontic success has made it possible to retain the pulpally involved teeth , the main reason behind this is the much advancements in endodontics .
the main causes of endodontic failure , making retreatment necessary , are thought to be insufficient cleaning and inadequate obtur... | aim : the study was designed to compare the efficiency of three different methods used for retreatment using a dental operating microscope ( dom ) and a stereomicroscope and to evaluate and compare the two methods for detection of residual obturation material after retreatment.background:the dom can play an important r... |
the patient was a 57-year - old man with a history of coming into contact with chemical gases during the war of 1981 .
he was referred to the emergency room ( er ) with an acute abdomen and hemorrhage about 6 years ago . at that time , the diagnosis was acute renal failure and myeloma .
the patient 's blood abnorma... | a 57-year - old male patient had myeloma .
he had severe pain in the left clavicle that did not respond to radiotherapy ; therefore , it was treated with radiofrequency thermal ablation ( rfta ) . under fluoroscopic guidance , two rf needles at a distance of 1.5 cm from each other were inserted into the mass and conv... |
remove the scorpion from its home jar and place it in a pre - chilled glass container ; next , place the jar containing the scorpion into a freezing environment ( -5 c ) for a minimum of two minutes .
this time may vary according to the age , size , species , etc . of the specific scorpion under study .
after two m... | we describe a modification of an existing tip - recording technique1,2 for electrophysiologically investigating short , peg - like sensory sensilla3,4 . on the mid - ventral surface of all scorpions are two appendages called pectines , which have dense fields of mechano- and chemosensory peg sensilla5,6 .
one method ... |
extracranial shunts are routinely used to divert cerebrospinal fluid ( csf ) into the extravascular compartment for the symptomatic relief from hydrocephalus .
. though rarely used , today ventriculopleural shunt ( vpls ) is considered in patients who have failed vps or are unsuitable either due to adhesions , infect... | cerebrospinal fluid ( csf ) diversion procedure has been used for long to treat hydrocephalus in children .
the principle of shunting is to establish a communication between the csf and a drainage cavity ( peritoneum , right atrium , and pleura ) .
ventriculoperitoneal shunt is used most commonly , followed secondl... |
proteases constitute the most important group of industrial enzymes used in the world today , accounting for approximately 50% of the total industrial enzyme market .
they have diverse applications in a wide variety of industries such as detergent , food , pharmaceutical , leather , peptide synthesis , and for the re... | the aim of this work was to study some biochemical characteristics of crude alkaline protease extracts from the viscera of goby ( zosterisessor ophiocephalus ) , thornback ray ( raja clavata ) , and scorpionfish ( scorpaena scrofa ) , and to investigate their applications in the deproteinization of shrimp wastes .
at... |
epidemiologic data were obtained from a nationwide survey of 269 villages conducted from august through september 2005 .
the country was divided into 4 ecologic zones on the basis of differences in elevation , temperature , and land cover type ( figure , panel a ) .
the number of villages selected in each zone was ... | plasmodium vivax is endemic to many areas of afghanistan .
geographic analysis helped highlight areas of malaria risk and clarified ecologic risk factors for transmission .
remote sensing enabled development of a risk map , thereby providing a valuable tool to help guide malaria control strategies . |
angioedema manifests as episodes of localized swelling in the dermis , subcutaneous tissue , mucosa and/or submucosal tissues . when angioedema affects the airway
, it is a potential cause of complete airway obstruction which could have fatal consequences if left untreated .
etiologies of this condition include ; i... | background : angioedema ( ae ) is edema of the skin , subcutaneous tissue and/or submucosal tissues , resulting from extravasation of intravascular fluid .
swelling of the supraglottic mucosa can lead to airway obstruction with consequent hypoxia , brain damage and death . to date ,
fiberoptic bronchoscope ( fob ) ... |
efforts have subsequently been made to identify new predictors of coronary artery disease ( cad ) as 20% of coronary events occur in the absence of traditional risk factors . to determine whether there are psychological risk factors for cad
has been a challenge for evidence - based medicine , however , it is not prud... | background : type - d personality has been identified as a risk factor for general and cardiac mortality in patients with coronary artery disease ( cad ) .
dobutamine - atropine stress echocardiography ( dase ) is an established method for non - invasive evaluation of myocardial ischemia in patients with cad .
the ... |
cognitively able adolescents and adults with a diagnosis of autism spectrum disorder ( asd ) , such as those once diagnosed with asperger s syndrome ( as ) or high functioning autism , commonly have restricted social participation as a result of social and communication deficits.14 they frequently report social isolati... | objectivethe purpose of the present study was to examine motivation for the contextual nature of motivations for social participation in cognitively able adolescents and adults with autism spectrum disorder , using self - determination theory as a theoretical framework.methodsfourteen australians and 16 taiwanese ( age... |
the use of nutritional supplements by athletes has been widespread in various sports and is growing rapidly .
extra energy providing , performance improvement , prevention of fatigue , and compensation for insufficient diet , are among major reasons reported for supplement use by athletes,[38 ] whereas , there is lit... | background : the consumption of nutritional supplements is high in various sports , whereas , there are not enough documents supporting the beneficial effects of supplements in athletes . in addition , there is no information about taking supplements by iranian students who participate in sports .
therefore , the goa... |
prospective epidemiologic studies have shown that blood levels of low - density lipoprotein cholesterol ( ldl - c ) significantly predict incident atherosclerotic cardiovascular disease ( cvd ) , and ldl - c - lowering therapy has been repeatedly demonstrated in many populations to reduce cvd risk .
this has led to t... | atherogenic dyslipidemia comprises a triad of increased blood concentrations of small , dense low - density lipoprotein ( ldl ) particles , decreased high - density lipoprotein ( hdl ) particles , and increased triglycerides . a typical feature of obesity , the metabolic syndrome , insulin resistance , and type 2 diabe... |
this work was supported by the national cancer institute at the national institutes of health , ellipse game - on u19 initiative for prostate cancer ( u19 ca148537 ) .
authors : david v. conti , kan wang , xin sheng , jeannette t. bensen , dennis j. hazelett , michael b. cook , sue a. ingles , rick a. kittles , sara ... | abstractprostate cancer incidence is 1.6-fold higher in african americans than in other populations .
the risk factors that drive this disparity are unknown and potentially consist of social , environmental , and genetic influences .
to investigate the genetic basis of prostate cancer in men of african ancestry , w... |
however , hyperinsulinism , hypopituitarism , or hereditary hepatic enzyme deficiencies are considered in patients with persistent or refractory hypoglycemia ( 1 ) .
insulinoma is the most common cause of hyperinsulinemic hypoglycemia ( 1 - 4/million patients ) and the second most common ( 10%-30% ) functioning pancr... | multiple endocrine neoplasia ( men ) mutation is an autosomal dominant disorder characterized by the occurrence of parathyroid , pancreatic islet , and anterior pituitary tumors .
the incidence of insulinoma in men is relatively uncommon , and there have been a few cases of men manifested with insulinoma as the first... |
nigella sativa l. ( ranunculaceae ) ( n. sativa ) is an annual herbaceous plant native to ( and cultivated in ) south west asia , and cultivated and naturalized in europe and north africa .
n. sativa seeds are commonly known as black cumin , and have been used as a spice and a condiment . in traditional medicine , n.... | nigella sativa has attracted healers in ancient civilizations and researchers in recent times . traditionally , it has been used in different forms to treat many diseases including asthma , hypertension , diabetes , inflammation , cough , bronchitis , headache , eczema , fever , dizziness and influenza .
experimental... |
acute myocardial infarction ( ami ) is one of the major problems influencing public health , and pci is one of the most effective method to reduce myocardial ischemia , ventricular remodeling and restore myocardial functions after ami .
timi flow grade was at first related to a postthrombosis 's coronary flow status ... | the study aim was to compare two different stress echocardiography interpretation techniques based on the correlation with thrombosis in myocardial infarction ( timi ) flow grading from acute coronary syndrome ( acs ) patients .
forty - one patients with suspected acs were studied before diagnostic coronary angiograp... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.