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ectopic pregnancy is a major cause of maternal morbidity and mortality , increasing in incidence worldwide .
ec - topic pregnancy is responsible for a significant proportion of maternal mortalities in the united states , comprising about 9% of all such deaths .
the accurate diagnosis of ectopic pregnancy can now be... | objectives : to study the surgical morbidity associated with laparoscopic management of tubal ectopic pregnancy compared with that of open laparotomy.methods:a retrospective study in an academic tertiary obstetrics and gynecology referral center was conducted from 2005 through 2007 .
forty - nine patients who had pat... |
tinnitus may be pulsatile and synchronous with the patient 's heartbeat or non - pulsatile and continuous .
pulsatile tinnitus is generally subjective but sometimes audible ( objective ) to the examiner by ear or by a stethoscope .
several vascular conditions can lead to pulsatile tinnitus , such as arterial bruit ... | although pulsatile tinnitus can be audible , objective demonstration of this heartbeat - synchronous sound has rarely been successful .
we report a rare case of pulsatile tinnitus in a 44-yr - old female patient , which was induced by a large mastoid emissary vein ( mev ) and objectively documented by doppler sonogra... |
we report a 66-year - old man who struggled with a painless left - sided chest mass for almost a year without an established diagnosis . prior to this report
only eight other cases have been documented in literature of an intercostal hernia being induced by coughing or other source of increase in positive pressure in... | cough - induced intercostal hernias without any type of external trauma are very uncommon .
there have been less than 10 cases documented in literature .
this clinical report describes a 66-year - old male who developed an intercostal hernia induced by a severe cough due to bilateral pneumonia and a subsequent rib ... |
obstructive sleep apnea syndrome ( osas ) is a common disorder , which is characterized by instability of the upper airway during sleep , resulting in reduction or elimination of airflow , oxygen desaturation , and sleep disruption .
approximately 4% of middle aged men and 2% of middle aged females are estimated to b... | introductionto evaluate the impact of continuous positive airway pressure ( cpap ) therapy on overactive bladder ( oab ) symptoms in women with obstructive sleep apnea syndrome ( osas).material and methodsone - hundred and fifty women underwent an overnight polysomnography study between may 2014 and september 2014 .
... |
a dearth of effective treatment strategies exist for global cerebral ischemia - reperfusion ( gci / r ) injury following successful resuscitation from out - of - hospital cardiac arrest ( ohca ) .
ohca is a devastating disease process with neurological injury accounting for a disproportionate amount of the morbidity ... | out - of - hospital
cardiac arrest ( ohca ) is a devastating disease
process with neurological injury accounting for
a disproportionate amount of the morbidity and
mortality following return of spontaneous
circulation . ... |
polymyositis ( pm ) is an idiopathic inflammatory myopathy with a prevalence of 1013 cases
per 100,000 people in japan1 . in pm ,
respiratory symptoms , such as interstitial pneumonia , are
frequently observed in patients with dermatomyositis3 .
therefore , physiotherapy may improve the limb muscle strength and... | [ purpose ] the purposes of this study were to quantify the serial changes in lower limb
and respiratory muscle strengths and to evaluate the acute effects of physiotherapy in
polymyositis patients . [ subjects and methods ] five patients ( 57.6 9.0 years , 50 to 72 ;
four females ) received physiotherapy five ... |
the incidence of melanoma has more than doubled over the last two decades , making it one of the fastest rising cancers worldwide .
currently , however , the mortality rate is significantly higher than the 1.3% diagnosed with incurable metastatic disease at presentation , implying its metastatic potential ( reviewed ... | malignant melanoma is a devastating disease whose incidences are continuously rising .
the recently approved antimelanoma therapies carry new hope for metastatic patients for the first time in decades .
however , the clinical management of melanoma is severely hampered by the absence of effective screening tools . ... |
they also shift the center of gravity to the non - paretic lower limb causing
asymmetric posture , decreased body balance , and reduced weight movement ability1 .
the balance ability of hemiplegic patients
suffering from stroke is the most important factor for them and their family members , and
its improvement... | [ purpose ] this study examined the effects of ramp gait training using lower extremity
patterns of proprioceptive neuromuscular facilitation ( pnf ) on chronic stroke patients
dynamic balance ability . [ subjects and methods ] in total , 30 stroke patients participated
in this study , and they were assigned rand... |
colorectal cancer is one of the most common malignancies , with one million new cases each year worldwide.1 liver metastases are detected in 40% to 60% of patients with colorectal carcinoma and in one third of the cases it is the sole site of disease.24 if untreated , the median survival of patients with hepatic metast... | backgroundhepatic artery infusion ( hai ) is indicated to treat unresectable colorectal hepatic metastases , with recent applications as a neoadjuvant or adjuvant treatment . traditionally performed with the infusion of fluoropyrimidine - based chemotherapy , it has been now tested with oxaliplatin or irinotecan and as... |
traumatic brain injury ( tbi ) is one of the leading causes of morbidity and death in pediatric patients , and diffuse injury is the most common cause of death in this population .
the contribution of brain edema in cases of tbi remains a critical problem and the role of the decompressive craniectomy in the managemen... | traumatic brain injury is a leading cause of morbidity and death in the pediatric population . in this study , we report a delayed unilateral traumatic brain swelling in a child with initial favorable evolution and sudden neurological deterioration after 4 days ; highlighting clinical , physiopathological and radiologi... |
increasing patient risks and costs associated with the delivery of health care services have been related to inappropriate and uncontrolled use of both diagnostic and therapeutic interventions which make evidence - based guideline recommendations for best clinical practice increasingly important . according to the beac... | increasing patient risks and costs associated with the delivery of health care services have been related to inappropriate and uncontrolled use of biomarkers which make evidence - based guideline recommendations for best practice increasingly important .
the translation of basic scientific discoveries into clinically... |
the concept of colony stimulating factor ( csf ) as a hematopoietic induction , differentiation , and growth factor was first discussed in 1966 ( 1 ) . a case of malignancy
was later reported with increased csf activation in serum and urine in 1974 ( 2 ) .
afterwards , it was demonstrated for the first time that cs... | granulocyte - colony stimulating factor ( g - csf ) is a naturally occurring glycoprotein that stimulates the proliferation and maturation of precursor cells in the bone marrow into fully differentiated neutrophils .
several reports of g - csf - producing malignant tumors have been published , but scarcely any in the... |
historically , the emergence of novel influenza virus subtypes in the human population has been associated with worldwide epidemics ( or pandemics ) . in recent history ,
the most devastating example of a new subtype emerging in the human population was the 1918 influenza virus , which expressed a subtype 1 hemagglut... | abstractnovel pandemic influenza viruses enter the human population with some regularity and can cause disease that is severe and widespread .
the emergence of novel viruses , historically , has often been coupled with the disappearance of existing seasonal virus strains . here ,
we propose that the elimination of ... |
extensive use of extended - spectrum cephalosporins , fluoroquinolones and carbapenems for treatment of these infections , has led to a significant increase of resistance in these bacteria .
resistance mechanisms such as production of -lactamases , plasmid - mediated quinolone resistance ( pmqr ) and carbapanemases h... | background : plasmid mediated quinolone resistance ( pmqr ) has been shown to play an important role in resistance not only to quinolones , but also -lactams and aminoglycosides .
in fact , qnr genes are frequently carried along with -lactamase determinants on the same plasmids .
we studied the prevalence of qnra ,... |
intestinal obstruction is a common surgical emergency frequently due to adhesions , tumors , inflammatory disorders , volvus , and external or internal hernias .
they can occur mainly in patients who have undergone gastric surgery and in multiple sites of the gastrointestinal tract .
there are many treatments for i... | phytobezoars are a rare cause of small - bowel obstruction and an accurate preoperative diagnosis is very difficult . after diagnosis , the majority of patients in this study underwent surgery .
the conventional management of small - bowel obstruction is done by laparotomy .
many studies have demonstrated that lapa... |
dystonia is a hypertonic condition caused by damage to the central nervous system , which is associated with pulling and stiffness of muscles .
there are several different forms of dystonia , which may affect only one muscle , groups of muscles , or muscles throughout the body .
cervical dystonia ( cd ) , also call... | purposecervical dystonia ( cd ) is a hypertonic condition caused by damage to the central nervous system .
very few studies have assessed the overall economic burden of the disease .
the objective of this study was to describe the utilization of health care resources of patients with cd in the uk primary care setti... |
a 66-year - old healthy man was referred from a private dental clinic for evaluation of a multilocular radiolucency at the left molar region of the mandible .
panoramic radiograph revealed a well - defined multilocular radiolucent area under the mandibular canal at the distal root of the second molar tooth ( fig .
... | developmental salivary gland defect is a bone depression on the lingual surface of the mandible containing salivary gland or fatty soft tissue .
the most common location is within the submandibular gland fossa and often close to the inferior border of the mandible .
this defect is asymptomatic and generally discove... |
estradiol-17 ( e2 ) , the predominant and most biologically active estrogen , is an 18 carbon ( c-18 ) steroid with an aromatic a - ring .
it is synthesized mainly by the ovary ; however , other organs and tissues , including adipose tissue , the brain ( neurons , astrocytes , and microglia ) , cells of the immune sy... | the concept that estrogens exert important neuroprotective actions has gained considerable attention during the past decade .
numerous studies have provided a deep understanding of the seemingly contradictory actions of estrogens .
we realize more than ever that the effects of estrogens ( with and without simultane... |
the primary objective of any diagnostic imaging modality is to accurately define the presence , the type , and the extent of disease in order to optimize patient management decisions and best plan therapeutic and surgical interventions . in women with suspected breast cancer ,
the aim of diagnostic imaging is to de... | women with newly diagnosed breast cancer may have lesions undetected by conventional imaging .
recently contrast - enhanced magnetic resonance mammography ( ce - mrm ) showed higher sensitivity in breast lesions detection .
the present analysis was aimed at evaluating the benefit of preoperative ce - mrm in the sur... |
it was found that job stress brought about hazardous impacts not only on nurses health but also in their abilities to cope with job demands .
this seriously impairs the provision of quality care and the efficacy of health services delivery .
stress has a cost for individuals in terms of health , wellbeing , and job... | introduction : nursing has been identified as an occupation that has high levels of stress .
job stress brought about hazardous impacts not only on nurses health but also on their abilities to cope with job demands.objectives:this study aimed at finding out the degree of work - related stress among the staff nurses a... |
anal fistula is a debilitating disease that requires complicated medical interventions to treat the patients ( 1 ) . according to the studies , the incidence of fistula - in - ano ranges from 2638% ( 2 ) .
its prevalence has not been exactly defined , but a few studies have reported its prevalence in limited populati... | introductionrecurrent and complex high fistulas remain a surgical challenge .
this paper reports our experience with the anal fistula plug in patients with complex fistulas.methodsdata were collected prospectively and analyzed from consecutive patients undergoing insertion of a fistula plug from january 2011 through ... |
insulin resistance is the critical pathophysiological disorder in the vast majority of individuals with type 2 diabetes ( t2d ) .
obesity is associated with tissue inflammation which is now recognized as a critical etiology of insulin resistance [ 14 ] .
circulating white blood cell counts , including absolute neut... | obesity is associated with tissue inflammation which is a crucial etiology of insulin resistance . this inflammation centers around circulating monocytes which form proinflammatory adipose tissue macrophages ( atm ) .
specific approaches targeting monocytes / atm may improve insulin resistance without the adverse sid... |
the endoscopic component separation technique [ ecst ] is an emerging technique for repair of large ventral hernias ( 1 ) .
the technique offers specific advantages to the open technique and to traditional ventral hernia repair .
although the technique is growing in popularity , these types of procedures represent ... | separation of components technique for incisional hernia repair is increasingly utilized as a strategy for hernia repair in both the obese and those with loss of abdominal domain .
endoscopic component separation technique [ ecst ] is increasingly performed to minimize wound complications associated with the open pro... |
short stature is defined as a stature more than 2 s.d . below the age - adjusted mean and
diverse
etiologies of short statue have been identified and include endocrinological short stature
caused by deficient secretion of growth hormone and/or thyroid hormone , excessive secretion
of cortisol due to pituitary /... | fgfr3 ( fibroblast growth factor receptor 3 ) is a gene responsible for the most common
form of osteodysplasia , achondroplasia , which results in extreme short stature .
an allelic
disorder , hypochondroplasia , however , presents with a much milder phenotype and is
sometimes indistinguishable from idiopathic ... |
failure to maintain mitochondrial integrity is linked to age - related conditions , such as neurodegeneration .
two genes linked to parkinson 's disease , pink1 and parkin , play a key role in targeting the degradation of dysfunctional mitochondria ( mitophagy ) . however , the mechanisms regulating the pink1/parkin ... | |
dedifferentiated chondrosarcoma ( ddcs ) is a rare and malignant form of primary bone tumor refractive to chemotherapy and radiotherapy .
we report a case of a 51-year - old male having a swelling and an ulcer distal to the left knee later diagnosed with dedifferentiated chondrosarcoma of proximal tibial and fibular ... | introduction : dedifferentiated chondrosarcoma ( ddcs ) is a rare and malignant form of primary bone tumor refractive to chemotherapy and radiotherapy
. it accounts for 1 - 2% of all primary bone tumors .
surgical resection , limb - salvage surgeries and amputation remain the mainstay of treatment .
the prognosis... |
a 39-year - old woman was seen in our clinic due to decreased visual acuity in her left eye .
her best corrected visual acuity ( bcva ) was 20/20 in the right eye and 20/200 in the left eye .
fundus examination revealed a yellow ovoid lesion with subretinal fluid in the surrounding retina in the superior extrafovea... | we report a case of recurrent choroidal neovascularization ( cnv ) in an eye with chorioretinal coloboma .
a 36-year - old woman presented complaining of decreased visual acuity ( va ) in her left eye .
best corrected visual acuity ( bcva ) was 20/200 and iris coloboma was observed .
funduscopy and fluorescein an... |
cell culture : canine melanoma cell lines , cmgd2 and cmgd5 , were kindly
provided by dr .
all cells were grown in
rpmi1640 containing 10% fbs and 1 anti - biotic / anti - micotic ( life techologies , carlsbad ,
ca , u.s.a . ) .
antibodies : antibodies were obtained from the indicated supplier :
anti - tot... | canine melanoma is one of the most important diseases in small animal medicine .
protein phosphatase 2a ( pp2a ) , a well conserved serine / threonine phosphatase , plays a
critical role as a tumor suppressor .
set / i2pp2a is an endogenous inhibitor for pp2a , which
directly binds to pp2a and suppresses its ph... |
overweight and obesity are increasing in many parts of the world and are one of the major risk factors causing health problems . preventing adolescents from becoming obese adults is important for their future health and may reduce health - care costs .
weight control and ideal body shape have evolved to be a main foc... | objectives . to explore
if self - perceived overweight in normal weight adolescents influence their weight development into young adulthood and if so , whether physical activity moderates this association . methods . a longitudinal study of 1196 normal weight adolescents ( 1319 yrs ) who were followed up as young ad... |
the functional assessment of cancer therapy - general ( fact - g ) questionnaire , designed to measure quality of life ( qol ) in cancer patients , has gone through many validation studies , both in its english and translated versions [ 2 - 5 ] .
however , little research has been conducted in south american spanish ... | backgroundthe fact - g has gone through many validation studies . however
, little research has been conducted in south american spanish speaking patients . the present study aimed to evaluate the fact - g spanish version 4 in uruguayan cancer patients.methodsthe data analyzed
were collected from 309 patients , wit... |
obesity has reached epidemic proportions in american adults and children and in most parts of the developed world [ 1 , 2 ] .
childhood obesity has indeed become one of the foremost issues in contemporary biomedical research particularly because of its importance in predicting adult overweight and obesity as well as ... | background .
since most people are aware of their clothing size ( cs ) , this prospective study explored the potential utility of cs as a proxy for body size and as a predictor of incident obesity - related health conditions in children .
methods .
this was a prospective , cross - sectional study of 725 children ... |
in 2014 , nearly 1 in 6 pediatric residents in the united states participated in an international health elective ( ihe ) in a resource - limited setting .
this increased activity occurs against a backdrop of a growing awareness of the importance of providing global health ( gh ) education for all residents , not mer... | resident participation in international health electives ( ihes ) has been shown to be beneficial , yet not all residents have the opportunity to participate .
we sought to determine whether participating in simulated global health cases , via the standardized simulation use for global away rotations ( sugar ) curric... |
it is usually done under local anesthesia with sedation under monitored anesthesia care ( mac ) or general anesthesia.[24 ] patients may feel discomfort due to pain , noise due to suction , manipulation of instruments and head - neck position . commonly used medications for mac are benzodiazepines , opioids and propofo... | background : analgesia and sedation are usually required for the comfort of the patient and surgeon during tympanoplasty surgery done under local anesthesia . in this study ,
satisfaction scores and effectiveness of sedation and analgesia with dexmedetomidine were compared with a combination of midazolam-fentanyl.mat... |
mucus hypersecretion is a notable aspect of a variety of chronic inflammation diseases including asthma , chronic bronchitis , bronchiectasis , and cystic fibrosis [ 1 , 2 ] .
excessive production of mucus leads to airway mucus obstruction , thus contributing to the morbidity and mortality in these diseases . as the ... | mucus hypersecretion is a distinguished feature of chronic inflammatory airway diseases .
interestingly , in this condition thyroid function is impaired with decreased level of triiodothyronine ( t3 ) , indicating potential link between low level of t3 and mucus hypersecretion .
but the underlying mechanisms are po... |
maternal mortality , which is widely accepted as a key indicator of population health and of socioeconomic development,1 is high in many african communities .
africa , particularly sub - saharan africa ( ssa ) , has made insignificant progress toward reducing maternal mortality rate in the continent where almost half... | backgroundmaternal mortality and morbidity reflect the status of population health and quality of life across nations .
poor understanding of the interplay of many antecedent factors , including sociocultural , economic and logistic factors , combined with an overwhelming poor health services delivery , is a basic ch... |
the public health impact of both childhood obesity and current rates of hiv infection and other sexually transmitted diseases ( stds ) among adolescents is substantial , and each problem represents a significant threat to the health of young people in the united states .
in addition to increased risk for cardiovascul... | the purpose of this study was to determine if body mass index ( bmi ) is associated with behaviors that may increase risk for hiv and other sexually transmitted diseases ( stds ) among us high school students .
we analyzed nationally representative data from the 20052011 national youth risk behavior surveys ( yrbs ) ... |
smooth muscle - derived uterine leiomyosarcomas are frequently aggressive tumours accounting for one third of all uterine sarcomas . even with early diagnosis , metastatic recurrence rates are high for leiomyosarcoma , with the lung , subcutaneous regions and abdominal cavity being the most frequent sites .
prognosis... | we report the case of a 60-year - old woman with metastatic high - grade uterine leiomyosarcoma who achieved a delayed response to second - line therapy with the marine - derived drug trabectedin ( yondelis , pharmamar ) .
we used 2-deoxy-2-[18f ] fluorodeoxyglucose ( fdg)-positron emission tomography ( pet - ct ) im... |
a large number of common genetic variants have been found to be associated with obesity phenotypes in europeans [ 13 ] .
variants in the fto ( fat mass and obesity - associated ) gene have demonstrated the strongest associations with obesity in europeans [ 1 , 4 , 5 ] .
however , results from a recent study in indi... | few studies have investigated the association between genetic variation and obesity traits in indian populations or the role of environmental factors as modifiers of these relationships . in the context of rapid urbanisation , resulting in significant lifestyle changes , understanding the aetiology of obesity is import... |
the relationship between illness and emotions has attracted for a long time the humanity . more than 300 years ago ,
thomas willis suggested that there was a relationship between diabetes and depression , and that diabetes was the result of long sadness ( 1 ) .
reports from the international diabetes federation i... | background : the depression is a significant problem in patients with diabetes .
this research is the first of it s kind conducted in the republic of kosovo to determine the prevalence of depression diagnosed in people with diabetes mellitus type 2 ( dmt2 ) and interrelation between depressive symptoms and behavior o... |
human immunodeficiency virus ( hiv)-associated cholangiopathy is a biliary obstruction resulting from benign stricture of the biliary tract in patients with advanced acquired immune deficiency syndrome ( aids ) ( 1 ) . the biliary tract is a frequent site of infection in patients with aids , and this complication was e... | we herein describe a case of progressive human immunodeficiency virus ( hiv)-associated cholangiopathy despite normalization of laboratory parameters , which had indicated liver dysfunction , after the initiation of combined anti - retroviral therapy ( cart ) .
hiv - associated cholangiopathy remains important as a d... |
according to the 2011 world health organization fact sheets , cancer has become a leading cause of death worldwide . in korea
, cancer has been the most common cause of death since 1990 , accounting for 27.6% of all deaths in 2012 .
since the vatican s 1980 declaration reaffirmed that disproportionate means of pres... | purposethe purpose of this study was to investigate and compare cancer treatment near the end - of - life ( eol ) over a 10-year period.materials and methodspatients with advanced solid cancer at seoul national university hospital who received palliative chemotherapy and had died were enrolled .
we categorized the co... |
to address some of the aforementioned outstanding questions , a study by tadokoro et al . published in this issue ( p. 505 ) ( 11 ) and another recent joint study by tang et al . published in nature immunology ( 12 ) used the increasingly popular technique of two - photon laser scanning microscopy to examine potential ... | regulatory cd4 t ( t reg ) cells control immune responses to self - antigens and pathogens . however , where t reg cells act to curtail effector t cells in vivo and what stage of effector t cell activation or differentiation is targeted by t reg cells remain unknown .
furthermore , a requirement for direct effector t... |
bacterial strains : three h. cinaedi strains were used in
this study and have been previously described .
the t22 and t34
strains were isolated from the feces of a healthy dog and hamster , respectively .
the
h. cinaedi ccug 18818 strain was obtained from the culture
collection at the university of gteborg ... | helicobacter cinaedi infection has been recognized as an increasingly
important emerging disease in humans .
infection with h. cinaedi causes
bacteremia , cellulitis and enteritis .
h. cinaedi has been isolated from
non - human sources , including dogs , cats and rodents ; however , it remains unclear whether... |
postpartum depression with symptoms such as anxiety , depressed mood , forgetfulness , and irritability is similar to depression in other periods of life , but its incidence is three times more in the first 5 weeks after delivery .
postpartum depression has serious consequences on the quality of life of the mothers a... | background : the objective of this study was an investigation of the association between depression and sleep quality.materials and methods : this cross - sectional study was performed on 360 delivered women that referred to thirty health - care centers in ardabil , iran .
the standard pittsburgh sleep quality index ... |
nonlinear spectroscopy and photostimulated second harmonic generation ( psshg ) are the two important tools to investigate the higher - order nonlinear optical processes , in particular , in semiconductors .
so , in order to observe the psshg , one needs to have a noncentrosymmetric process .
these include ( 1 ) th... | cu - doping effects in cdi2nanocrystals are studied experimentally .
we use the photostimulated second harmonic generation ( psshg ) as a tool to investigate the effects .
it is found that the psshg increases with increasing cu content up to 0.6% and then decreases due to the formation of the cu - agglomerates .
... |
developmental disability ( dd ) is a group of severe chronic conditions that are attributable to an impairment in physical , cognitive , speech , language , psychological , or self - care areas that are manifested during the developmental period ( younger than 22 years of age ) .
intellectual disability ( i d ) is a ... | low bone mass density ( bmd ) , a classical age - related health issue and a known health concern for fair skinned , thin , postmenopausal caucasian women , is found to be common among individuals with developmental / intellectual disabilities ( d / ids ) .
it is the consensus that bmd is decreased in both men and wo... |
the avoidance of long - term immunosuppression by achieving immunological tolerance would be the ultimate solution to improving long - term patient survival and giving kidney transplant patients a better quality of life .
unfortunately , owing to its complex immunopathogenesis , true immunological tolerance to avert ... | the existence of t - cell subsets naturally committed to perform immunoregulation has led to enthusiastic efforts to investigate their role in the immunopathogenesis of transplantation .
being able to modulate alloresponses , regulatory t cells could be used as an immunodiagnostic tool in clinical kidney transplantat... |
the digestive disease week ( ddw ) meeting was held in may 18 - 21 , 2013 in orlando , usa . as in previous meetings , endoscopic ultrasound ( eus ) was an important topic in this meeting because it has been widely used in diagnosis and treatment of gastrointestinal and pancreatic diseases .
new progresses discussed ... | endoscopic ultrasound ( eus ) was one of the leading topics in 2013 digestive disease week meeting and some new progresses were highlighted at the eus monothematic symposium during the period .
although eus - fine needle aspiration has increased the accuracy of eus in the diagnosis of pancreatic and biliary diseases ... |
a complete list of categorized references for all articles captured in this review can be found here .
| though much attention in the medical literature has focused on the ethics of critical care , it seems to be disproportionately weighted toward clinical issues . on the presumption that the operational management of an intensive care unit ( icu ) also requires ethical considerations
, it would be useful to know what t... |
spontaneous cerebrospinal fluid ( csf ) fistula of the skull base is an uncommon condition associated with multiple etiologies and can have a variable presentation . of note , obese , middle - aged , and multiparous women
most commonly develop this condition.1
2 intractable , watery discharge from the nose ( rhinor... | spontaneous cerebrospinal fluid ( csf ) rhinorrhea due to a skull base defect requires prompt diagnosis and treatment .
multiple surgical options are available for repairing the fistula , including the two - layer fascial apposition method and use of a pedicled nasal - septal flap .
a 44-year - old obese woman pr... |
soon after the enactment of the medicare program in 1965 , it became clear that fulfilling the mandate of providing health care security to medicare beneficiaries would require assurances that funds were used effectively and that beneficiaries received care consistent with medical quality standards .
the systems desi... | this article outlines the development , successes , and future directions of the medicare peer review organization ( pro ) program .
as established by the tax equity and fiscal responsibility act of 1982 , the purpose of the pro program is to promote the quality , medical necessity , and appropriateness of services r... |
the crowns of erupted human teeth are covered by symbiotic microbial communities , mainly composed of gram - positive saprophytic bacteria which are normally harmless to the tooth .
these communities adhere as biofilms to the highly mineralized enamel that constitutes a barrier which is impermeable to microorganisms ... | dental caries is a chronic infectious disease resulting from the penetration of oral bacteria into the enamel and dentin .
microorganisms subsequently trigger inflammatory responses in the dental pulp .
these events can lead to pulp healing if the infection is not too severe following the removal of diseased enamel... |
it has a propensity for leptomeningeal spread via the cerebrospinal fluid ( csf ) circulation , and approximately 3035% of the patients present with evidence of metastatic disease .
currently , patients with disseminated medulloblastoma are classified according to chang 's operative staging system , where the extent ... | purpose . to correlate the radiological aspects of metastases , the response to chemotherapy , and patient outcome in disseminated childhood medulloblastoma .
patients and methods .
this population - based study concerned 117 newly diagnosed children with disseminated medulloblastoma treated at the institute gustav... |
despite our efforts to keep fit , eat sensibly , and avoid accidents , we inevitably succumb to age - related diseases .
cells can not reproduce indefinitely , presumably due to the unavoidable accumulation of dna errors . to achieve longevity ,
we are urged ( among many other precautions ) to avoid ionizing radiat... | polyphenols are among the most valuable and widely studied food components . in the laboratory , they are readily extractable with aqueous alcohol .
an aliquot rapidly decolorizes a measured portion of abts , a stable deep blue radical ion .
the semilog plot of light absorption versus time is typically a straight l... |
a considerable number of patients with surgical emergencies may develop visceral or retroperitoneal oedema due to severe inflammation , shock and fluid resuscitation .
this oedema may prevent primary closure of the abdomen or may lead to dangerously high intra - abdominal pressure ( iap ) and abdominal compartment sy... | postoperative intra - abdominal hypertension ( iah ) is a frequent occurrence in critically ill patients operated on for severe abdominal trauma , secondary peritonitis or ruptured abdominal aortic aneurysm .
iah may progress to abdominal compartment syndrome ( acs ) with new - onset organ dysfunction
. early recog... |
in randomized controlled trials ( rcts ) , the participants are allocated to two groups of intervention and control for the comparison of some outcomes between them ( 1 ) .
rcts are considered the most valuable method to assess the efficacy of treatments whether or not the result of a comparison is statistically sign... | context : randomized controlled trials ( rcts ) are important tools for evidence - based health care decisions .
it is , therefore , important that they be conducted and reported with the highest possible standards .
the aim of this study was to evaluate the reporting quality of the rcts published in nephrology uro... |
a total of 94 volunteered patients who met inclusion criteria of the study and diagnosed as fms , and consulted to the outpatient clinic because of widespread bodily pains , and complaints of poorly localized chronic pain enrolled in the study .
patients with complaints of radicular pain , neurological deficit , disc... | objective : to investigate the clinical and demographic characteristics and functional status of the patients with fibromyalgia syndrome ( fms).methods : ninety - four patients with the diagnosis of fms were included in the study .
all patients were evaluated with short form 36 for quality of life ( sf-36 ) , pain , ... |
hearing disability derives from a deficiency in hearing ability and the performance of an individual in communication .
the severity of the disability depends on the nature and magnitude of hearing loss and , consequently , on the hearing difficulties experienced by the listener.2
hearing disability derives from a... | introduction hearing difficulties can be minimized by the use of hearing aids .
objective the objective of this study is to assess the speech perception and satisfaction of hearing aids users before and after aid adaptation and to determine whether these measures are correlated .
methods the study was conducted ... |
multimorbidity is often defined as the concurrent presence of multiple chronic conditions [ 14 ] .
the prevalence of multimorbidity is highest among the elderly , with estimated rates ranging from 55% to 80% [ 5 , 6 ] . with advancements in medical technology and prolonged life expectancy ,
approximately 81 million... | background .
individuals with multimorbidity are vulnerable to poor quality of care due to issues related to care coordination .
ambulatory care sensitive hospitalizations ( acshs ) are widely accepted quality indicators because they can be avoided by timely , appropriate , and high - quality outpatient care . obje... |
chronic kidney disease ( ckd ) is associated with increased cardiovascular events and mortality when the glomerular filtration rate declines below 60 ml / min [ 13 ] .
one significant event in ckd patients is the development of calcitriol deficiency secondary to the reduction / absence of kidney 1-hydroxylase which ... | vitamin d deficiency appears to be an underestimated risk factor for cardiovascular disease in patients with chronic kidney disease .
evidence from both basic science and clinical studies supports the possible protective role of vitamin d beyond its effect on mineral metabolism .
toxicity of pharmacologic doses of ... |
primary renal synovial sarcoma ( prss ) was initially described by faria et al . in 2000
detection of characteristic cytogenetic abnormality t(x , 18 ) within this group of tumors led to the recognition of a renal synovial sarcoma .
these tumors harbour characteristic translocation t(x ; 18 ) ( p11 ; q11 ) describe... | primary renal sarcoma is rare tumor comprising only 1% of all renal tumours .
synovial sarcomas are generally deep - seated tumors arising in the proximity of large joints of adolescents and young adults and account for 510% of all soft tissue tumours .
primary synovial sarcoma of kidney is rare and has poor progno... |
in vivo bioluminescence imaging ( bli ) is a low - cost , noninvasive , and valuable tool for studying physiological and pathological processes at cellular and molecular levels .
this technology has been applied to various biological models to diagnose disease , monitor therapies , and facilitate drug development [ 1... | bioluminescence tomography ( blt ) is a promising tool for studying physiological and pathological processes at cellular and molecular levels . in most clinical or preclinical practices ,
fine discretization is needed for recovering sources with acceptable resolution when solving blt with finite element method ( fem ... |
pycnodysostosis , a rare bone dysplasias with an estimated prevalence of 1/million is characterized by physical features of dwarfism , hypoplastic nails , blue sclera , proptosis , parrot beak nose , frontal bossing and radiographic features of osteosclerosis , multiple fractures , acro - osteolysis of the distal phala... | pycnodysostosis is a rare sclerosing bone disorder characterized by short stature , brachycephaly , short / stubby fingers , open cranial sutures / fontanelle , and diffuse osteosclerosis , where multiple fractures of long bones and osteomyelitis of the jaw are common complications .
we present a rare case of pycnody... |
the unicornuate uterine anomaly is often difficult to diagnose and usually low on the list of differential diagnoses for pelvic pain and dysmenorrhea . the authors present a case of a rudimentary uterine horn as a cause for continued pelvic pain and dysmenorrhea in a previously hysterectomized woman
a 43-year - old w... | background : the unicornuate uterine anomaly is often difficult to diagnose and usually low on the list of differential diagnoses for pelvic pain and dysmenorrhea . the authors present a case of a rudimentary uterine horn as a cause for continued pelvic pain and dysmenorrhea in a previously hysterectomized woman.case r... |
the online version of this article ( doi:10.1007/s00441 - 008 - 0613 - 9 ) contains supplementary material , which is available to authorized users .
the major aim of our study has been to test several combinations of factors associated with a cryopreservation procedure by using slow- and rapid - cooling methods for ... | isolated caprine early - staged follicles were submitted to osmotic tolerance tests in the presence of sucrose , ethylene glycol ( eg ) , or nacl solutions and were exposed to and cryopreserved ( by slow or rapid cooling ) in mem alone or mem supplemented with sucrose , eg ( 1.0 or 4.0 m ) , or both . when follicles w... |
laparoscopic cholecystectomy ( lc ) is recognized as the gold standard method for treating symptomatic gallstone disease .
gallbladder perforation with subsequent gallstone spillage can occur with higher frequency in lc than in traditional open approach .
these stones are usually benign but can migrate to various s... | abstractgallbladder perforation with subsequent gallstone spillage can occur with higher frequency in laparoscopic cholecystectomy than in traditional open approach .
gallstone abscess formation from stone spillage post - cholecystectomy is extremely rare .
we present a case of para - spinal abscess formation 5 yea... |
amputation was the standard method for achieving local control of tumors of the proximal tibia prior to the early 1970s . since the advent of effective chemotherapeutic regimens , limb sparing surgery provides improved patient function and acceptance when compared to amputation [ 41 , 43 , 46 ] .
the first limb sa... | backgroundthe few available studies documenting the long - term survival of cemented proximal tibial endoprostheses for musculoskeletal tumors do not differentiate between stem designs or patient diagnosis .
there is wide variation in survival rates reported , possibly a result of this heterogeneity in patient popula... |
millions of people take time off work annually to treat and recover from work - related musculoskeletal pain or impairment in the lower back or upper extremities .
manual handling and lifting are the major causes of work - related back pain . however , back pain and in particular lower back pain are also common in ot... | background : brickfield workers in india perform manual materials handling ( mmh ) and as a result , are at a high risk of developing oxidative stress .
this results in an alteration of the various markers of metabolic oxidative stress at the cellular level . since red blood cell ( rbc )
is the central point where ... |
obesity and its associated diseases such as noninsulin dependent diabetes , atherosclerosis , and cardiovascular disease are a main cause of mortality and morbidity . development of adipose tissue is a complex process in which growth factors , cytokines , adipokines , proteases , and hormones control extensive modi... | background .
the pituitary adenylate cyclase activating polypeptide ( pacap ) may affect adipogenesis and adipose tissue formation through interaction with its g - protein - coupled receptor vpac1 .
methods . we have used a monoclonal antibody ( mab 23a11 ) blocking vpac1 in mouse models of nutritionally induced ob... |
the loss of an eye has been regarded as the greatest misfortune , and indian literature showed a 23-fold higher incidence of tumors of the eye as one of the main reasons in children below 15 years of age .
surgical procedures in the removal of an eye are classified into three general categories : evisceration , enucl... | purpose : the purpose of this study was to analyze the prevalence of ocular defect among different age groups , gender , side involved , and etiology.materials and methods : a retrospective study was conducted among referred ocular defect patients in a dental college in southern part of india over a 5 years period ( 20... |
maternal health plays a significant role in determining as well as predicating the health of the offspring later in their life .
fetal exposure to maternal diabetes in utero increases the risk of obesity / adiposity , glucose intolerance , and type 2 diabetes for offspring in later life [ 25 ] .
animal studies reve... | this study was designed to assess the effect of maternal diabetes in rats on serum glucose and insulin concentrations , insulin resistance , histological architecture of pancreas and glycogen content in liver of offspring .
the pregnant rat females were allocated into two main groups : normal control group and strept... |
the international organization for standardization ( iso 15189:2012 document ) claims that necessary improvements and potential sources of non - conformities , either technical or concerning the quality management system , shall be systematically identified and corrected ( 1 ) .
the above standard deals with quality ... | summarydiagnostic blood samples collected by phlebotomy are the most common type of biological specimens drawn and sent to laboratory medicine facilities for being analyzed , thus supporting caring physicians in patient diagnosis , follow - up and/or therapeutic monitoring .
phlebotomy , a relatively invasive medical... |
monocular downbeat nystagmus is a very rare manifestation of combined nuclear - supranuclear ophthalmoparesis that is seemingly a secondary dysfunction of cerebellar - modulated crossed oculovestibular fibers of the superior cerebellar peduncle , integrator neurons , or posterior commissure crossing fibers originating ... | we report a patient with acute cerebral infarction of the left paramedian thalamus , upper mesencephalon and cerebellum who exhibited ipsilateral oculomotor nerve palsy and contralateral downbeat nystagmus .
the site of the infarction was considered to be the paramedian thalamopeduncular and cerebellar regions , whic... |
non - melanomatous skin cancer is the most common cancer worldwide , with basal cell carcinoma ( bcc ) representing the largest portion , with over 3 million cases diagnosed annually .
although it can occur anywhere , it most frequently occurs in areas with excessive sun exposure such as the head and neck .
factors... | skin cancer remains the most common cancer worldwide , and basal cell carcinoma represents the largest portion of non - melanomatous skin cancers with over 3 million cases diagnosed annually .
locally advanced disease is frequently seen in the elderly posing clinical challenges regarding proper treatment.we report on... |
cancer of the breast is the most common cancer in both developing and developed countries and is responsible for over one million in an estimated ten million neoplasms diagnosed in both sexes worldwide .
breast cancer is also the primary cause of cancer death among women globally , responsible for about 425,000 death... | background .
nearly 70% of women diagnosed with breast cancer in ghana are in advanced stages of the disease due especially to low awareness , resulting in limited treatment success and high death rate . with limited epidemiological studies on breast cancer in ghana , the aim of this study is to assess and understand... |
the pelvic floor muscles ( pfms ) play a significant role in continence control , pelvic organ
support1 , and stabilization of the
lumbo - pelvic region2 .
recent studies have
found that the pfms perform subsidiary roles in posture control and ventilation3 , and contribute to spinal stability4 . the most establ... | [ purpose ] the purpose of this study was to compare the effect of childbirth delivery
method on vaginal pressure and abdominal thickness during the valsalva maneuver ( val ) .
[ subjects ] thirty healthy female volunteers ( 2639 years of age ) were selected for this
research .
their delivery histories were : ... |
as producers and decomposers , bacterioplankton are a key component of microbial food webs and play significant roles in biogeochemical cycles . in
algae bacteria symbiosis , bacteria extensively participate in substance cycles , oxidation reduction activities , and regulate the balance of phytoplankton ecosyst... | phycosphere environment is a typical marine niche , harbor diverse populations of microorganisms , which are thought to play a critical role in algae host and influence mutualistic and competitive interactions .
understanding quorum sensing - based acyl - homoserine lactone ( ahl ) language may shed light on the inte... |
two thousand years ago , hippocrates described hydatid disease of the liver as the liver full of water . tyson in 1687 suggested the parasitic nature of the disease .
the details of its clinical aspect , however , only became clear at the beginning of this century .
hydatid disease is common in the sheep - rearin... | objective : we describe herein a surgical technique , whereby we use a liposuction device for the laparoscopic treatment of hepatic hydatid cysts ( hhc).methods : ten patients with 12 hepatic hydatid cysts were treated with this technique .
all patients received pre- and postoperative antiscolecidal medications .
t... |
the half - lives for spontaneous hydrolysis of trehalose and sucrose at 25 c are 6.6 106 years and 440 years .
the half - lives for decomposition of the hydrolysis products glucose and fructose are 96 years and 70 days , respectively . whereas sucrose and trehalose differ by a factor of 15000 in their rates of uncat... | |
prostate cancer is the most commonly diagnosed nonskin malignancy in men and is the second leading cause of cancer - related death in the united states .
the incidence of prostate cancer is also rapidly increasing in korea . in the united states ,
approximately 90% of patients with prostate cancer are diagnosed wit... | purposein advanced prostate cancer , malignant cells generally tend to spread into the bone , and metastasis into nonregional lymph nodes ( nrlns ) at the time of initial diagnosis is relatively rare .
we investigated the prognostic significance of nrln metastasis in patients receiving hormonal therapy and chemothera... |
since 1994 , bacterial artificial chromosome ( bac ) libraries have become an invaluable resource tool to initiate genomics research in theareas of genome sequencing , physical mapping , positional cloning , complex analysis of targeted genomic regions , and analysis of gene structure and function [ 18 ] .
more recen... | we describe the construction and characterization of a publicly available bac library for the tea plant , camellia sinensis . using modified methods ,
the library was constructed with the aim of developing public molecular resources to advance tea plant genomics research .
the library consists of a total of 401,280... |
cdse / zns semiconductor nanocrystals or quantum dots ( qds ) possess unrivalled photophysical properties , such as size tunable emission wavelengths , extremely high extinction coefficients over a broad absorption spectrum and enhanced photostability compared to organic fluorophores [ 14 ] .
moreover , several conce... | cdse / zns core / shell quantum dots ( qds ) are used as efficient frster resonance energy transfer ( fret ) acceptors in a time - resolved immunoassays with tb complexes as donors providing a long - lived luminescence decay .
a detailed decay time analysis of the fret process is presented .
qd fret sensitization i... |
neonatal herpes simplex virus ( hsv ) infection manifests either as skin , eye , mouth ( sem ) disease , central nervous system ( cns ) disease , or disseminated disease .
disseminated neonatal hsv infection characteristically presents as a sepsis syndrome with fever , hepatitis , and pneumonia with or without enceph... | disseminated neonatal herpes simplex virus infection usually presents with multi - organ involvement .
untreated , this disease has a mortality rate of approximately 80% . here , we describe a well - appearing 3-week old infant with isolated compensated hepatic failure caused by hsv-2 . |
before the mid1990s families referred to social services because of child welfare concerns were routinely screened using child protection procedures regardless of the reason for referral ( gibbons , 1995 ; parton , thorpe , & wattam , 1997 ) . following the review undertaken in child protection : messages from research... | since the 1990s the way in which social workers respond to referrals of children to children 's social care departments has evolved .
it has moved through a process that screens families out of child protection assessment to a system aiming to screen families in where necessary , and now uses a holistic assessment ... |
acute aortic dissection ( aad ) has become a treatable disease due to recent advances in new therapeutic approaches for the management of heart and arterial diseases ; however , development of quick and economic diagnostic methods remains a challenge .
variability in disease presentation often obscures diagnoses , an... | acute aortic dissection ( aad ) is a serious vascular disease .
currently the diagnosis relies on clinical and radiological means whereas serum biomarkers are lacking .
the purpose of this study was to identify potential serum biomarkers for aad using isobaric tags for relative and absolute quantitation ( itraq ) a... |
hepatitis c virus ( hcv ) infection affects 2050% of end - stage renal disease ( esrd ) patients and contributes significantly to morbidity and mortality following renal transplantation ( rtx ) [ 1 , 2 ] .
hcv infection has a prevalence of about 2.666% among rtx patients in different countries with great genotype div... | introduction . hepatitis c virus ( hcv ) infection is an independent risk factor for renal transplantation ( rtx ) .
immunosuppression minimization can render better quality of life to these patients .
methods .
we analyzed 132 hcv - positive rtx patients ( group a ) transplanted under tolerance induction protoco... |
male 8-week - old wistar rats ( 200 250 g ; specific pathogen - free ( spf ) ; japan shizuoka
laboratory center ) were individually housed in cages ( 33 23 23 cm ) under controlled
conditions of temperature ( 245 1c ) , humidity ( 55 5 % ) and light ( 12 h light12 h
dark cycle ) .
rats were ... | milk is an effective post - exercise rehydration drink that maintains the net positive
fluid balance .
however , it is unclear which components are responsible for this effect .
we
assessed the effect of milk protein solution ( mps ) obtained by dialysis on body fluid
retention .
milk , mps , milk electroly... |
nonalcoholic fatty liver disease ( nafld ) is a clinicopathological syndrome characterized by hepatic steatosis with or without active inflammation ( 1 ) in patients with a negligible alcohol intake .
there is growing concern about nafld , not only because this is a common liver disorder with a worldwide distribution... | we investigated the association between nonalcoholic fatty liver disease ( nafld ) and plasma adiponectin levels and insulin resistance .
we recruited study subjects among one hundred and eighty one persons who were examined abdominal ultrasound at routine screening tests . a standard interview ( consumption of alcoh... |
pediatric atopy is increasingly prevalent and represents a significant financial and quality of life burden for children and families .
in addition to significant morbidity , effects of disease and its treatment , such as fatigue and discomfort as well as frequent clinic visits , may result in academic and social cha... | pediatric atopy is increasing in prevalence and creates a significant financial and quality of life burden for children and families ( e.g. , frequent clinic visits , academic , and social challenges ) .
thus , it is important to understand modifiable risk factors related to disease onset or exacerbation in young chi... |
endodontic failure occurs even when the highest standard and the most meticulous treatment procedure is adhered to . when conventional root canal treatment fails , endodontic retreatment is the preferred option as it is one of the most conservative methods .
the main goal of retreatment is to regain access to the api... | objective . to compare the efficacy of protaper retreatment files in removing three different obturating materials
. study design .
forty - five human , single - rooted premolars were divided into three experimental groups .
group 1 was obturated with gutta - percha and ah plus sealer , group 2 was obturated with... |
erosive adenomatosis of the nipple ( ean ) was first defined by jones in 1955 who referred to it as florid papillomatosis or papillary adenoma of the nipple . in 1959
legal , et al . coined the term erosive adenomatosis because of the clinical and pathologic findings .
adenoma of the nipple , sub areolar papillomat... | erosive adenomatosis of the nipple ( ean ) is a rare , benign neoplasm of breast lactiferous ducts .
peak incidence is in the fifth decade in women .
clinically , it is mistaken for eczema during early stages and paget 's disease at later stages .
we present a young lady with ean who was advised mastectomy .
it... |
behet 's disease ( bd ) is a multisystem recurrent inflammatory disorder that primarily affects young men .
it is usually manifested as recurrent oral and genital ulcers , and skin and eye alterations .
the neurological complication of bd , termed neuro - behet 's disease ( nbd ) , occurs in 5~30% of patients with ... | a 25-year - old man presented with blurred vision and chronic headache .
his brain mri revealed bilateral frontal pachymeningeal enhancement with leptomeningeal enhancement . the patient had experienced recurrent oral ulcer and had anterior uveitis and papulopustules skin lesion .
we diagnosed him with hypertrophic... |
the membranous labyrinth of the inner ear is a sensory system for sound , motion , and gravity , consisting of the cochlea , vestibular system , and the endolymphatic sac .
the lumen of the membranous labyrinth is filled with endolymph , a k - rich , positively polarized fluid , whereas the surrounding spaces are fil... | objective : to locate components and target proteins of relevance for the camp and cgmp signaling networks including camp and cgmp phosphodiesterases ( pdes ) , salt - inducible kinases ( siks ) , subunits of na+ , k+-atpases , and aquaporins ( aqps ) in the human saccule .
methods : the human saccule was dissected o... |
in the previous issue of critical care , hochreiter and colleagues presented another piece of evidence suggesting that procalcitonin ( pct ) may indeed be a valuable diagnostic parameter to guide antibiotic treatment duration .
misuse of antimicrobial agents has been a long - lasting problem in intensive care units (... | every day , critical care physicians around the world face the same challenge of the optimal timing of antimicrobial administration : when to start and when to stop antibiotics .
duration of antibiotic therapy for sepsis is mostly based on expert opinion , but its reduction is arguably the most promising approach to ... |
prostate cancer ( pca ) is an important disease for public health care in the united states ( us ) , europe , and korea because it is first in prevalence and second in mortality among men 's cancer .
the incidence rate of pca has markedly increased over the past 10 years in korea .
much evidence suggests that the r... | purposetype iii 5- reductase ( srd5a3 ; steroid 5- reductase 3 ) may be associated with the progression of prostate cancer ( pca ) .
the aim of our study was to determine whether the length of ac repeats in the srd5a3 gene is associated with the risk of pca and the expression of androgen receptor ( ar ) protein in ko... |
the incidence of lung cancer in the people s republic of china has doubled in the past decade1 likely because of aging population , poorly controlled cigarette smoking , and air pollution associated with rapid economic growth.2,3 similar to the tumor histology distribution of lung cancer in industrialized countries , >... | objectivethe objective of this study was to compare hospital costs per treatment cycle ( hctc ) for nonchemotherapy drugs and nondrug care associated with platinum - based doublets in the first - line setting for advanced nonsquamous non - small - cell lung cancer ( advns - nsclc ) in chinese patients.methodspatients r... |
the persistent controversy [ 13 ] swirling about the safety and efficacy of the bisphosphonate ( bp ) class of medications has prompted us to provide an objective review of the early development of these drugs .
understanding the original studies leading to the introduction of bps for indications ranging from the all... | the documented history of the development of the bisphosphonate drugs is reviewed in sufficient detail to permit independent evaluation of the consistency of the conclusions reached from the available data .
the evidence developed during the early interval of these studies 19601975 was sufficient to establish that py... |
large posteromedial asymmetrical osseous defects are often seen in proximal tibia while performing a primary total knee arthroplasty ( tka ) in severe varus knees .
majority of these are peripheral uncontained defects . depending upon the size of the defect ,
these can be treated with cementoplasty , cement with sc... | background : large posteromedial defects encountered in severe varus knees during primary total knee arthroplasty can be treated by cementoplasty , structural bone grafts or metallic wedges . the option is selected depending upon the size of the defect .
we studied the outcome of autograft ( structural and impaction ... |
mht occurs when the mean 24-h ambulatory blood pressure measurement ( abpm ) 130/80 mm hg or mean non - clinical ( home or a pharmacy ) periodic blood pressure measurement is 135/85 mm hg despite normal ( < 140/90 mm hg ) polyclinic blood pressure .
the prevalence of mht was observed to be 1017% in general population... | backgroundthis study aimed to determine the prevalence of masked hypertension ( mht ) and its association with asymptomatic organ damage ( aod ) in a low socioeconomic district of ankara , turkey.material/methodswe retrospectively reviewed data obtained from the medical records of 712 patients with no known diagnosis o... |
it is the most common cause if stroke and renal failure . in case of no suitable treatment and control of hypertension , 50% of hypertensive patients will die of coronary artery disease , 33% of stroke and 10 - 15% of renal failure . in different studies , the prevalence of hypertension has been reported from 10% to 17... | introduction : measurement tools designed to ensure the achievements of studies objectives must be evaluated .
based on the health promotion model ( hpm ) , the present study was conducted to assess the validity and reliability of the designed questionnaire of hypertensive patients nutritional perceptions.methodology... |
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