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post - traumatic meniere 's disease ( ptmd ) is meniere 's syndrome that develops after acoustic or physical trauma .
the histopathologic characteristics of ptmd are identical to those of idiopathic meniere 's disease.1 ) the causes of traumatic insult that lead to ptmd include blows to the head , temporal bone fract... | there are only a few reports of post - traumatic meniere 's disease and there is few literature that contains detailed data associated with the disease .
we report a case of post - traumatic meniere 's disease .
he suffered from tinnitus , fluctuating sensorineural hearing loss , and recurrent vertigo .
symptomat... |
breast conserving therapy ( bct ) has been a preferred treatment method for early breast cancer since equivalent loco - regional control and overall survival with improved cosmetic outcome compared with mastectomy was reported in several studies . the harvard scale proposed by harris et al .
, which has been used to ... | purposethe purpose of this study is to evaluate objective cosmetic outcomes and factors related to breast - conserving therapy ( bct ) using the bcct.core software.materials and methodsfifty - one patients who received bct with informed consent were evaluated using the bcct.core software .
patients were divided into ... |
despite that the current guidelines for the treatment of non - small cell lung cancer ( nsclc ) endorse bevacizumab added to the chemotherapy backbone of carboplatin and paclitaxel , there is a lack of published real - world evidence documenting the use of this combination in subpopulations either excluded or under - r... | backgroundreal - world evidence is lacking on the impact of bevacizumab added to carboplatin / paclitaxel ( bev + cp ) therapy versus cp alone for patients with non - squamous non - small cell lung cancer ( ns - nsclc ) , particularly in those excluded from clinical trials.methodsthis is a retrospective electronic medi... |
migraine is a common disorder with overall prevalence of 515% [ 13].the prevalence of migraine in females is higher ( 622% ) compared to males ( 37% ) [ 46 ] .
the pathogenesis of migraine is multifactorial and a number of genetic and environmental factors have been suggested .
recently , association of migraine wi... | metabolic syndrome is associated with migraine but there is no study comparing the characteristics of migraine with and without metabolic syndrome from southeast asia .
this study was therefore undertaken to compare the clinical characteristics of migraine in patients with and without metabolic syndrome and insulin r... |
bipolar disorder ( bd ) is associated with recurrent exacerbation of manic , depressed or mixed episodes , leading to functional impairment , substance abuse , risk of suicide , accidents , and increased cost of care.16 antipsychotics are a proven option in the treatment of bd.711 although clozapine has never been appr... | bipolar disorder ( bd ) is associated with periodic symptom exacerbations , leading to functional impairment , and increased risk of suicide .
although clozapine has never been approved for the treatment of bd , it is occasionally used in severe mania .
the aim of the study is to evaluate the risks and benefits of ... |
chronic obstructive pulmonary disease ( copd ) is characterised by chronic airflow limitation associated with the inflammatory process of the lung .
acute exacerbations of copd ( aecopd ) are characterized by dyspnea , increase in the production and purulence of sputum .
these aecopds impair the health status of th... | background : acute exacerbations of chronic obstructive pulmonary disease ( aecopd ) are important causes of morbidity and mortality . in this study
, we analyzed procalcitonin ( pct ) levels in aecopd and stable period of copd in order to evaluate usage of pct in the prediction of the severity of aecopd , and its va... |
angiogenesis , the process of generating new blood vessels based on pre - existing ones ( 1 ) , is a complex multistep dynamic process that comprises matured vessel changes , pericyte detachment , extracellular matrix ( ecm ) degradation and remodeling , proliferation , migration and assembly of endothelial cells ( ecs... | angiogenesis is the process of generating new blood vessels based on existing ones , which is involved in many diseases including cancers , cardiovascular diseases and diabetes mellitus .
recently , great efforts have been made to explore the mechanisms of angiogenesis in various diseases and many angiogenic factors ... |
the anterior vaginal wall is a fascial diaphragm , tautly strung between the pericervical ring above and the urogenital diaphragm below , and attached laterally to the two fascial white lines [ 13 ] . as such , the pubocervical fascia functions like a trampoline , providing all direction support to the proximal urethra... | introduction and hypothesisthis study aims to compare native tissue abdominal and vaginal paravaginal repair , and to investigate whether surgical outcome was independent of operative route.methodsretrospective comparison of 111 displacement cysto - urethrocoeles , repaired between 1997 and 2007 .
treatment was by su... |
rooted cuttings ( 5070 cm in length ) of hybrids between p. deltoides ( l155 - 079 , female ) and p. nigra ( 71077 - 2 - 308 , male ) , produced at inra , orleans ( france ) , were cultivated in 20 20 cm pots in the greenhouse , under natural daylight conditions ( 750 mms , maximal photon flux density ) , with... | to investigate the response of poplar hybrids to drought , leaves were collected from plants to which water was suspended for 8 and 13 days . after measuring the respective relative water content , rnas were isolated from leaves of moderately and severely droughted plants and from control plants , and illumina rna seq... |
a fistula is defined as a pathologic tract connecting two hollow organs , or one hollow organ and the skin .
men are affected two- to four - times more commonly ; the reason is thought to be partially due to the higher abundance of anal glands .
infection of the anal glands and crypts is thought to be the cause of ... | magnetic resonance imaging ( mri ) is the best imaging modality for preoperative assessment of patients with anal fistula .
mri helps to accurately demonstrate disease extension and predict prognosis .
this in turn helps make therapy decisions and monitor therapy . the pertinent anatomy
, fistula classification a... |
according to the well - known 20th - century american physicist and philosopher of science thomas samuel kuhn , from time to time sciences face paradigm shifts . these paradigm shifts open up new approaches and bring remarkable changes to their development .
it seems that the editorial of the first issue of the e... | this paper maps the ethical issues that arise in the context of personalised medicine .
first , it highlights the ethical problems related to increased predictive power of modern diagnostic interventions . such problems emerge because the ability to identify individuals or groups of individuals that can potentially b... |
in this case report , we describe a refractory cmml case without eosinophilia harboring a pdgfrb rearrangement leading to a favorable response with imatinib .
we believe this case demonstrates the utility of broad spectrum genomic profiling in refractory cmml cases as an opportunity to uncover additional treatment op... | |
in 2005 , two publications introduced methods for massively parallel dna sequencing , marking the beginning of a dizzying free - fall in sequencing costs that continues today with no obvious end in sight . to enable the flexible application of these ' next - generation ' technologies in the context of human genetics , ... | the field of human genetics is being reshaped by exome and genome sequencing .
several lessons are evident from observing the rapid development of this area over the past 2 years , and these may be instructive with respect to what we should expect from ' next - generation human genetics ' in the next few years . |
reducing cardiovascular risk and chronic kidney disease ( ckd ) progression are two of the primary goals of ckd management [ 1 , 2 ] .
excessive sodium intake has been extensively researched for its relationship with cardiovascular risk factors , in particular hypertension and volume overload [ 35 ] .
new research ... | there is consistent evidence linking excessive dietary sodium intake to risk factors for cardiovascular disease and chronic kidney disease ( ckd ) progression in ckd patients ; however , additional research is needed . in research trials and clinical practice , implementing and monitoring sodium intake present signific... |
c57bl/6 mice obtained from taconic laboratories were used between 9 and 15 weeks of age . mice ( 9 weeks old )
were castrated , sham operated , or implanted with 1.5 mg dihydrotestosterone ( males ) or 0.1 mg 17-estradiol ( females ) pellets in a slow ( 21 days ) release form .
glucose tolerance tests and insulin t... | objectiveto investigate how insulin sensitivity and glucose metabolism differ in adipocytes between different fat depots of male and female mice and how sex steroids contribute to these differences.research design and methodsadipocytes from intra - abdominal / perigonadal ( pg ) and subcutaneous ( sc ) adipose tissue f... |
morphologically , there are at least ten reported subtypes of pulmonary artery sarcoma : undifferentiated sarcoma , leiomyosarcoma , rhabdomyosarcoma , fibrosarcoma , myxosarcoma , malignant mesenchymoma , chondrosarcoma , angiosarcoma , osteosarcoma , and malignant fibrous histiocytoma [ 1 , 2 ] . the tumors appear to... | a 63-year - old female presented with abnormal lung shadows but had , apart from this , few symptoms .
computed tomography ( ct ) revealed multiple nodules and blockage of the pulmonary artery .
she was immediately diagnosed with pulmonary artery sarcoma based on a careful differential diagnosis and underwent surge... |
encephalotrigeminal angiomatosis , or sturge - weber syndrome ( sws ) , is an uncommon nonhereditary developmental condition with hemangioma as a disturbing feature .
the pathognomonic features of this syndrome are venus angiomas of the leptomeninges extending over the cerebral cortex with ipsilateral angiomatous les... | vascular lesions represent one of the rare disorders affecting overall quality of life of a child .
a wide variety of these conditions are known , ranging from a simple nevus to life - threatening hemangiomas .
these conditions make the treatment options more complex due to the fear of uncontrollable bleeding .
t... |
most foreign body ingestions occur in the pediatric population and include coins , toys , magnets , and batteries .
conversely , most foreign body ingestions in adults include food ( meat ) boluses , bones , toothbrushes , spoons , and razor blades .
although most of the ingested foreign bodies pass spontaneously... | in most cases of ingested foreign bodies , endoscopy is the first treatment of choice .
moreover , emergency endoscopic removal is required for sharp and pointed foreign bodies such as animal or fish bones , food boluses , and button batteries due to the increased risks of perforation , obstruction , and bleeding . h... |
ozone ( o3 ) , a gas discovered in the mid - nineteenth century , is a molecule consisting of three atoms of oxygen in a dynamically unstable structure due to the presence of mesomeric states .
the gas is colorless , acrid in odour and explosive in liquid or solid form .
it has a half - life of 40 min at 20c and ab... | ozone ( o3 ) gas discovered in the mid - nineteenth century is a molecule consisting of three atoms of oxygen in a dynamically unstable structure due to the presence of mesomeric states .
although o3 has dangerous effects , yet researchers believe it has many therapeutic effects .
ozone therapy has been utilized an... |
indian mustard [ brassica juncea ( l. ) czern & coss . ] is a crop of tropical as well as temperate zones requiring somewhat cool and dry weather for satisfactory growth and development .
high temperature at flowering stage causes reduction in seed yield as it may lead to pollen sterility . although mustard is a long... | indian mustard [ brassica juncea ( l. ) czern & coss . ] is a long day plant , which requires fairly cool climatic condition during growth and development for obtaining better seed yield .
various workers have correlated crop growth and development with energy requirement parameters , such as growing degree days ( gd... |
socio economic status or ses has been considered as one of the most important health risk factors nowadays .
indeed , it would be not only a considerable predictor of people 's morbidity and mortality , but also really important in health policies , preventing , and intervening practices in public health researches [... | backgroundstage is one of the most important prognostic factors for the cancer diagnosis , including the breast cancer .
studies have found that the rate of breast cancer late - stage diagnosis , among the women with lower socioeconomic status , is more than the others .
the aim of this study was investigation the ... |
alzheimer disease ( ad ) is the most common cause of dementia and the most important degenerative disorder of the brain ( 1 ) .
based on statistical analyses , it has been estimated that more than 5 million people in the united states have dementia and that it will , increase to 13 million by the year 2050 ( 2 ) .
... | context : alzheimer disease ( ad ) is the most common cause of dementia . in regards to the world s aging population , control and treatment of ad will be one of the major concerns of global public health in the next century .
alzheimer disease was not mentioned with the same phrase or its equivalent in traditional m... |
cardiac involvement in hypereosinophilia is rare ; when present , its various manifestations range from heart failure to thromboembolic events and/or atrial fibrillation , which are caused by fibrous thickening of the endocardium of one or both ventricles and mural thrombosis.1)2 ) toxocara canis ( t. canis ) is a comm... | cardiac involvement in hypereosinophilia is rare ; when present , it manifests as ventricular thickening , usually with fibrous tissue and mural thrombosis .
we present a case of a 57-year - old man with an abnormal right ventricular apex with eosinophilia , which was caused by toxocara canis infection . |
in order to analyze rare ctcs in the blood of cancer patients , it is necessary to enrich , isolate and identify the tumor cells in the presence of billions of red blood cells and the tens of millions of nucleated hematopoietic cells .
the most commonly used form of enrichment relies on antibodies against the epithel... | enrichment of rare circulating tumor cells ( ctcs ) in blood is typically achieved using antibodies to epithelial cell adhesion molecule ( epcam ) , with detection using cytokeratin ( ck ) antibodies .
however , epcam and ck are not expressed in some tumors and can be downregulated during epithelial - to - mesenchyma... |
the prevalence of intellectual disabilities ( i d ) in india is not well known .
india has the world 's largest children population who are at higher risk of developmental disabilities .
the prevalence of i d in india varies by age , gender , population - type , and place of residence .
these demographic and geog... | background : intellectual disability ( i d ) is a global public health concern . prevalence of i d and its association with age and other demographic factors is required for planning purposes in india.objective:this study analyzed the age - adjusted prevalence of i d in rural and urban populations and its correlation w... |
the blowfly sarconesiopsis magellanica ( diptera : calliphoridae ) is of medical interest as it is a potential mechanical vector of pathogens such as viruses , bacteria , protozoa , and helminths [ 13 ] .
its larvae could produce facultative myiasis without affecting live tissue due to its feeding habits as a necroph... | we evaluated extracts taken from s. magellanica third instar larvae fat body and haemolymph using a diabetic rabbit model and compared this to the effect obtained with the same substances taken from lucilia sericata larvae .
alloxan ( a toxic glucose analogue ) was used to induce experimental diabetes in twelve rabbi... |
diabetes is the most common chronic metabolic disorder that is full of progressive and debilitating complications , involve 6 - 15% of the population . and it is the main cause of blindness , end - stage renal disease , dialysis and amputation .
type 2 diabetes include 90 - 95% of all cases of diabetes that occurs in... | background : training and continuous dynamic communication between patients and health professionals in chronic diseases like diabetes , is important . the aim of this study is to evaluate the effects of diabetes self - care group education and nurse- telephone follow - up on glycemic control and compliance with treatm... |
( rutaceae ) dried ripe fruit is used for dispelling colds , soothing liver , and analgesia .
e. rutaecarpa can ease depression , relieve dyspepsia , and exert analgesic , sedative , antibacterial , and antioxidant activities , as well as other pharmacological effects . up to now , alkaloids are the main active ingre... | evodia rutaecarpa ( juss . ) benth .
( rutaceae ) dried ripe fruit is used for dispelling colds , soothing liver , and analgesia .
pharmacological research has proved that alkaloids are the main active ingredients of e. rutaecarpa .
this study aimed to rapidly classify and identify the alkaloids constituents of e... |
the 4-tiered diagnosis - specific graded prognostic assessment ( ds - gpa ) score is the most recent brain metastases survival prediction model .
it is considered to represent an important evolution and refinement of the initial gpa score and is expected to become widely adopted , comparable to the radiation therap... | summarybackgroundassessment of cancer- and host - related prognostic factors has a long tradition in patients with brain metastases . in continuation of large - scale studies performed by the radiation therapy oncology group ( rtog ) in the united states ,
the 4-tiered diagnosis - specific graded prognostic assessmen... |
chronic obstructive pulmonary disease ( copd ) is a leading cause of morbidity and mortality worldwide .
tobacco smoking has been recognised as the most important risk factor for copd for a long time .
previously most of the studies on copd mainly focused on smoking as a risk factor but recent studies showed that n... | background : tobacco smoking has been recognized as the most important risk factor for chronic obstructive pulmonary disease ( copd ) for a long time , but recent studies have shown that nonsmokers also contribute to a significant proportion of copd .
this study was performed to find out the proportion of nonsmoker i... |
the genes encoding the enzymes required for udp - xylose and udp - galactose synthesis in trichomonas vaginalis have been identified and the products of the recombinant enzymes analysed .
| graphical abstractthe genes encoding the enzymes required for udp - xylose and udp - galactose synthesis in trichomonas vaginalis have been identified and the products of the recombinant enzymes analysed.highlights xylose and galactose are components of trichomonas vaginalis glycans .
t. vaginalis udp - xylose syn... |
arsenic is a group i carcinogen and occurs predominantly in inorganic form as arsenate ( asv ) and arsenite ( asiii ) .
in addition , human activities have caused an accumulation of arsenic in soils through production / use of arsenic - based pesticides , manufacture of arsenic based compounds , smelting of arsenic... | the toxicity of arsenic in soil and ground water is one of the most important environmental problems particularly in south - east asia .
arsenic - polluted irrigation water creates hazard in soil environment and also in crop quality . in the present study , response of black gram ( vigna mungo l. ) to arsenic with or... |
for decades , breast implants have been used to augment or reconstruct the female breasts .
three types of implants are available : implants filled with saline , implants filled with silicone gel ( sg ) and silicone oil and implants filled with a mixture of saline and cellulose , called the monobloc hydrogel ( mh ) .... | this study is focused on the properties of the monobloc hydrogel ( mh ) breast implant , which has been around for more than 30 years , and to see how it behaves with regard to health complaints as sometimes seen in some patients who had received silicone gel ( sg ) breast implants .
patients responded to a question... |
a 64-year - old korean man with weight loss , anorexia , and abdominal pain was admitted .
the patient s blood pressure was 109/69 mm hg , his body temperature was 38.1c , his heart rate was 88 beats per minute , and his respiratory rate was 20 breaths per minute . on physical examination , coarse crackles were au... | traditionally , adult intussusception has required a bowel resection because of the malignancy risk . a patient with anorexia ,
weight loss , and abdominal pain visited our clinic .
a physical exam and imaging study revealed no acute peritoneal signs . a colonoscopy for biopsy and bowel reduction
was attempted . ... |
there is a need to integrate medicine and innovative technology in our public health system to provide rapid , efficient , accurate , and cost - effective results for identification and antimicrobial susceptibility testing ( ast ) of pathogens .
automated identification / ast systems can aid in rapid diagnosis of bac... | the present study was designed to compare a fully automated identification / antibiotic susceptibility testing ( ast ) system bd phoenix ( bd ) for its efficacy in rapid and accurate identification and ast with conventional manual methods and to determine if the errors reported in ast , such as the ( very major errors ... |
it follows a recurrent course that can become refractory to treatment over time . combination chemotherapy including bortezomib , thalidomide , and lenalidomide is a highly effective salvage therapy for patients with relapsing or refractory multiple myeloma .
the development of soft tissue plasmacytomas has been repo... | multiple myeloma is an incurable and slow growing plasma cell neoplasm .
the introduction of new drugs has increased the number of treatment options .
bortezomib , the first - in - class proteasome inhibitor , has been shown to have a significant antitumor activity in the treatment of relapse / refractory patients ... |
bees , ranging from wild solitary species to highly social and managed species like honey bees , play key roles in natural and agricultural ecosystems worldwide ( 13 ) .
recent losses of honey bees and wild bees have been attributed to pesticide exposure , poor nutrition , increased parasite loads , habitat degradati... | abstractas pollinators , bees are cornerstones for terrestrial ecosystem stability and key components in agricultural productivity . all animals , including bees , are associated with a diverse community of microbes , commonly referred to as the microbiome .
the bee microbiome is likely to be a crucial factor affecti... |
hepatocellular carcinomas ( hcc ) are histopathologically characterized by their abundant vascularity and the presence of a tumor plate / sinusoid system , and these structures and related hemodynamics have been shown to change dramatically during the process of multistep carcinogenesis.110 transarterial chemoembolizat... | transarterial chemoembolization ( tace ) using iodized oil ( lipiodol ) ( lp - tace ) as a carrier of chemotherapeutic agents has been routinely performed to control hepatocellular carcinomas ( hcc ) in japan , and its use has yielded fairly beneficial therapeutic results .
lipiodol is thought to pass through the tum... |
the century - old baeyer villiger
( bv ) reaction is the oxidative cleavage of a carbon carbon
bond adjacent to a carbonyl ; this process transforms ketones to esters
and cyclic ketones to lactones using peracids .
while
this reaction has proven to be very useful to synthetic chemists ,
it has a number of... | the baeyer villiger monooxygenases ( bvmos ) are
a family of bacterial flavoproteins that catalyze the synthetically
useful baeyer villiger oxidation reaction .
this involves the
conversion of ketones into esters or cyclic ketones into lactones
by introducing an oxygen atom adjacent to the carbonyl group . ... |
somatostatin receptor 2 ( sstr2 ) is a negative regulator of cell proliferation in human
breast cancer . since there is little information about sstr2 in canine mammary gland tumor
( mgt ) , we clarified its distribution and expression level in normal mammary gland , benign
mgt and malignant mgt .
sstr2 express... | |
admission to an intensive care unit ( icu ) is not only stressful to the patients but the patients ' family members.12 in fact , admission to an icu is viewed as a crisis for both patients and their families ( p. 491)3
, because they are not adequately mentally prepared for such a stressful situation.4 having a lov... | background : admission to an intensive care unit ( icu ) is not only stressful to the patients but the patients ' family members .
families are believed not to receive their required attention because their needs are incorrectly and inaccurately evaluated by the health care team .
therefore , the present study aime... |
we retrospectively reviewed the medical records of patients with mm admitted to the department of hematology / oncology at kameda medical center , kamogawa , japan , from january 2006 to may 2014 .
diagnosis of myeloma and evaluation of treatment response were performed according to the imwg criteria.(1,2 ) ob was de... | the emergence of oligoclonal bands ( ob ) has been reported in patients with multiple myeloma ( mm ) after stem cell transplantation ( sct ) or successful chemotherapy .
however , their clinical relevance remains unclear .
we reviewed the clinical records of mm patients from january 2006 to may 2014 .
treatment r... |
heterotopic pregnancy is simultaneous presence of intrauterine ( iu ) and extrauterine pregnancy with an incidence is 1/30,000 of all spontaneous pregnancies .
it was first defined by duverney , in the year 1708 , as an autopsy finding in a patient who died of ectopic pregnancy who also had an iu pregnancy . with ram... | we present a case of sonographic demonstration of quadruplet heterotopic pregnancy consisting of twin intrauterine ( iu ) pregnancy and a twin adnexal pregnancy after ovulation induction ( oi ) with clomiphene citrate ( cc ) and timed intercourse ( ti ) .
both heterotopic pregnancy and spontaneous twinning are freque... |
late onset psychiatric disorders often represent a challenge for the psychiatrists as far as the diagnosis and management issues are concerned .
the elderly patients have generally been reported to have associated medical , especially neurological illnesses and are also prone to side effects of various psychotropic m... | late onset psychiatric disorders are often associated with organic factors , either medical or neurological .
mania occurring for the first time in the elderly population is rarely reported .
we hereby report a patient with first episode mania who was investigated in detail , but no organic factors were found .
h... |
infantile nystagmus syndrome ( ins ) is an ocular motor disorder characterized by involuntary oscillations that are typically bilateral , conjugate , uniplanar , horizontal - torsional , pendular or jerk with increasing velocity slow phases ( cemas 2001 ) .
current ins treatment relies on optical ( eg , spectacles , ... | we investigated the effects of contact lenses in broadening and improving the high - foveation - quality field in a subject with infantile nystagmus syndrome ( ins ) . a high - speed , digitized video system was used for the eye - movement recording .
the subject was asked to fixate a far target at different horizont... |
ehlers - danlos syndrome ( eds ) is a heterogeneous collection of connective tissue disorders characterized by varying degrees of skin hyperextensibility , joint hypermobility , and tissue fragility .
surgical treatment of eds patients is complicated by the extreme fragility of their vessels and tissues .
the purpo... | backgroundehlers - danlos syndrome ( eds ) is a heterogeneous collection of connective tissue disorders characterized by varying degrees of skin hyperextensibility , joint hypermobility , and tissue fragility .
surgical treatment of eds patients is complicated by the extreme fragility of their vessels and tissues .
... |
rheumatoid arthritis ( ra ) is the most common chronic , systemic , inflammatory autoimmune disorder , affecting approximately 1% of the world 's population .
it is characterized by persistent synovitis , pain , swelling , and progressive destruction of the small joints of the hands and feet , accompanied by function... | rheumatoid arthritis ( ra ) is the most common autoimmune disorder .
loss of th1/th2 and th17/treg balance has been reported in several inflammatory autoimmune diseases .
this study was to investigate th1 , th2 , th17 , and treg differentiation and related cytokines in ra patients .
the frequencies of th1 , th2 ,... |
in the past several decades , due to the progress in worldwide agricultural production , use of pesticides has been significantly increased .
increased public concern about the dietary risks of pesticides led to a major change in pesticide law . as a result , current pesticide policy in europe and america is focused ... | a new electrochemical method for determination of imidacloprid using chronopotentiometry on thin film mercury and glassy carbon electrode was presented .
the most important experimental parameters of chronopotentiometry were examined and optimized with respect to imidacloprid analytical signal .
imidacloprid provid... |
androgen insensitivity syndrome ( ais ) , also called testicular feminization syndrome , is a form of x - linked male pseudohermaphroditism that is clinically recognized in patients with a female phenotype .
miss ab , a 20-year - old female , attended our outpatients department ( opd ) on 16 august 2007 with complain... | embryonal cell carcinoma is a rare clinical entity .
we report a case of a 20-year - old patient who presented with lump lower abdomen for last two months with primary amenorrhea and poorly developed secondary sexual characteristics .
ultrasonography ( usg ) whole abdomen showed lower abdominal mass approximately 1... |
elevated permeability of endothelium is crucial in atherosclerosis because it allows circulating lipoproteins and inflammatory cells to infiltrate into intima .
zonula occludens-1 ( zo-1 ) plays an important role in binding occludin to cytoarchitecture and regulating cellular permeability .
hypercholesterolemia... | purpose . hypercholesterolemia and tight junctions play important roles in atherosclerosis . but
the relationship between these two factors is unclear . in the present study
, we investigated whether hypercholesterolemic serum could change the permeability of endothelial cells through altering expression and/or dis... |
in the recent past , the importance of the surprisingly diverse class of non - coding rna molecules ( ncrnas ) has been widely recognized ( 14 ) .
the key feature of all ncrnas is that they are not translated into proteins but rather exert their functions at the rna level .
ncrnas have been identified in unexpected... | non - protein - coding rnas ( ncrnas ) fulfill a wide range of cellular functions from protein synthesis to regulation of gene expression .
identification of novel regulatory ncrnas by experimental approaches commonly includes the generation of specialized cdna libraries encoding small ncrna species .
however , suc... |
myotonic dystrophy ( dm ) is a multisystemic disease whose most prominent manifestations are myotonia , atrophy , and progressive weakness of neuromuscular systems .
the prevalence are different in different geography , but it ranges from 1:100,000 to 1:10,000 ( 1 ) .
although there is no information on the prevale... | congenital myotonic dystrophy type 1 ( dm1 ) presents severe generalized weakness , hypotonia , and respiratory compromise after delivery with high mortality and poor prognosis .
we presented a congenital dm1 of premature twins in the 30th week of gestation .
these twins were conceived by in vitro fertilization ( i... |
renal transplant recipients are prone to develop secondary malignancies , especially lymphoid malignancies , carcinomas of the skin and lip , carcinomas of the vulva and perineum , in situ carcinomas of the cervix of the uterus , kaposi 's sarcoma , hepatocellular carcinomas , renal carcinomas , and various soft tissue... | post - transplant lymphoproliferative disorders ( ptld ) have been recognized as a complication of immunosuppression and occur with a reported incidence of 1 to 8% of recipients receiving solid organ transplantation .
ptld are classified into two major categories , polymorphic and monomorphic ptld .
the majority of... |
the principle of ivitc is to achieve maximum drug concentration as close to the tumor for maximum therapeutic effect with the lowest systemic concentration .
introduction of intravitreal chemotherapeutic drugs dates back to early 1960 where ericson and rosengren treated six eyes with intravitreal injection of 0.30.4 ... | targeted therapy in retinoblastoma ( rb ) is widely accepted as the current management tool with an aim of increasing drug availability at the tumor location .
inevitably the effect is several times higher compared to systemic delivery of chemotherapeutic drugs and carries less systemic toxicity . despite tremendous ... |
they show a bimodal age distribution occurring in childhood and in the 4 and 5 decades , with a slight female preponderance . because of the juxtaposition of the adrenal gland to the kidney
, it is not uncommon for acc to involve the renal parenchyma . on the other hand , renal cell carcinoma ( rcc )
also frequentl... | adrenocortcal carcinoma is an extremely uncommon entity with an incidence of two in one millionth population . here
we present a 60 year gentleman with pain in abdomen , nausea , and backache , and weight loss .
contrast enhanced computed tomography ( cect ) abdomen revealed a heterogenous well defined mass measuri... |
among cardiac arrhythmias atrial fibrillation ( af ) is the most common one in the united states .
symptomatic af may also reduce the quality of life , cardiac performance and the functional status .
the prevalence of af in the us among patients who are older than 40 years is approximately 2.3% , increases to almos... | backgroundatrial fibrillation is a relatively common arrhythmia often seen in patients with permanent pacemakers . in this study we aimed to assess the incidence of atrial fibrillation in patients whose pacemakers were programmed to pace in the right ventricle ( vvi ) and compared it with patients whose pacemakers were... |
general procedure : to a 1-dram screw cap vial was added the diene or the allene substrate ( 0.1 mmol , 1.0 equiv ) followed by the dithiophosphoric acid catalyst 3f , 3 g or 3h ( 0.01 mmol , 0.1 equiv ) and activated 4 molecular sieves ( 20 mg ) . to the mixture
the vial was sealed and allowed to stand for 48 h at ... | chiral brnsted acids have become an invaluable tool for achieving a variety of asymmetric chemical transformations under catalytic conditions while avoiding the use of toxic and expensive metals18 .
while the catalysts developed so far are remarkably effective at activating polarized functional groups , chemists have... |
h bonds as coupling partners for suzuki coupling with organoboron reagents has recently been made possible using pd(ii)/pd(0 ) catalysis . while this new catalytic reaction provides a variety of new disconnections for carbon
carbon bond formation , cross - coupling of c(sp)h bonds with organoboron reagents is current... | there have been numerous developments in c h activation reactions in the past decade . attracted by the ability to directly functionalize molecules at ostensibly unreactive c
h bonds , chemists have discovered reaction conditions that enable reaction of c(sp2)h and c(sp3)h bonds with a variety of coupling partners .... |
datasets from the 7 large studies with sample sizes greater than 250 participants ( 2 by the same sponsor using essentially identical methodologies ) were collected and analyzed .
the essential features of the 7 trials are shown in the table . using the alzheimer 's disease assessment scale
cognitive subscale ( ada... | objective : to examine the variability in performance among placebo groups in randomized controlled trials for mild cognitive impairment ( mci).methods : placebo group data were obtained from 2 national institute on aging ( nia ) mci randomized controlled trials , the alzheimer 's disease cooperative study ( adcs ) mci... |
furthermore , it is the sixth leading cause of cancer deaths in women and the second most common cause of death among those with gynecologic cancers .
approximately 90% of ovarian cancers are of epithelial origin , with the remaining 10% composed of sex cord - stromal tumors ( 5% to 8% ) , germ cell tumors ( 3% to 5%... | objectiveswe conducted a systematic review and meta - analysis to summarize current evidence regarding the association of parity and duration of breastfeeding with the risk of epithelial ovarian cancer ( eoc).methodsa systematic search of relevant studies published by december 31 , 2015 was performed in pubmed and emba... |
synthesizing a bucky shuttle or a nanopeapod , consisting of a nanotube and fullerene has opened new horizons of investigations into the properties of nanostructures for researchers . at present time
it is supposed , that bucky shuttles can be used , for example , as nanosized memory elements or to serve as a b... | a nanocapsule for safe and effective methane storage is investigated by the method of molecular dynamics .
the mass content of methane in the nanocapsule reaches the value of 14.5 mass% .
the nanocapsule consists of two parts : a locking chamber and a storage area .
the locking chamber is the nanotube ( 10.10 ) ,... |
leprosy also known as hansen 's disease is a chronic multi - system disease caused by mycobacterium leprae ( hansen 's bacillus ) .
it is a transmissible infectious disease mainly affecting the skin , peripheral nerves and mucous membrane .
the world health organization ( who ) classification ( 1997 ) is based on t... | background : leprosy is primarily a disease of developmental countries .
about 4 million people have or are disabled by leprosy .
eighty - six percent of leprosy patients reside in southeast asia and brazil .
india accounts for up to 70% of total cases.aim:to evaluate the incidence of orofacial lesions in treated... |
cerebrospinal fluid ( csf ) leak is a major complication of skull base surgery , occurring after 10% of transcranial skull base procedures , with ranges from 1% to 30%.1
2
3
4 given the associated increased risk of central nervous system infection , prompt intervention often ensues following suspicion of a csf l... | objectives pseudo - cerebrospinal fluid ( csf ) rhinorrhea is a rare phenomenon , presumed to result from aberrant autonomic reinnervation of the paranasal mucosa following injury to the greater superficial petrosal nerve or periarterial plexus . in this report
, we discuss the case of a postoperative patient with p... |
sjgren - larsson syndrome ( sls ) is an autosomal recessive neurocutaneous disorder characterized by clinical triad of congenital ichthyosis , diplegia or tetraplegia , and learning disability / mental retardation .
sls is caused by mutation in the gene for fatty aldehyde dehydrogenase ( faldh ) which catalyzes oxida... | sjgren - larsson syndrome ( sls ) is a rare autosomal recessive disorder characterized by triad of congenital ichthyosis , spastic paresis , and mental retardation .
it is an inborn error of lipid metabolism caused by deficiency of the enzyme fatty aldehyde dehydrogenase .
we report our observations of six children... |
necrotizing fasciitis is an often fatal infection of the softtissue that will commonly begin after some form of trauma .
this softtissue infection involves the superficial fascial layers ( or hypodermis ) of the abdomen , extremities , or perineum .
this infection of the deep layers of skin and subcutaneous tissues... | escherichia coli ( e. coli ) is associated with necrotizing fasciitis ( type i ) and can induce enough damage to tissue causing hypoxia .
three ester derivatives of the broad - spectrum antibiotic ciprofloxacin were placed into bacteria culture simultaneously with the parent ciprofloxacin ( drug 1 ) to ascertain the ... |
3.1.4.39 ) , is a member of the family of nucleotide pyrophosphatases / phosphodiesterase ( npp1 - 7 ) and is also referred , as npp2 .
it is to a glycoprotein with four possible n - glycosylation sites , synthesized as a pre - proenzyme and is secreted to extracellular space following two n - terminal cleavages ( 27... | autotaxin ( atx ) is an extracellular lysophospholipase d ( lysopld ) released from normal cells and cancer cells .
activity of atx is detected in various biological fluids .
the lysophosphatidic acid ( lpa ) is the main product of atx .
lpa acting through specific g protein - coupled receptors ( lpa1-lpa6 ) affe... |
immunoglobulin subtype g4-related disease ( igg4-rd ) is a fibroinflammatory disease of unknown etiology , which may present with a wide array of manifestations , with reported cases involving nearly every organ system .
one of the most common and well - described manifestations is type 1 autoimmune pancreatitis .
... | introduction immunoglobulin subtype g4-related disease ( igg4-rd ) is a fibroinflammatory disease of unknown etiology , with manifestations involving nearly every organ system .
its association with foreign bodies is not established . here , we present a novel case of igg4-rd in response to foreign body injection . ... |
secretory granules ( sgs ) are the hormone and neuropeptide containing organelles of neuroendocrine cells that release their content upon depolarization - induced , ca - dependent exocytosis .
the biogenesis and stimulated secretion of these high - copy number organelles have been intensively studied in various inter... | the biogenesis , maturation , and exocytosis of secretory granules in interphase cells have been well documented , whereas the distribution and exocytosis of these hormone - storing organelles during cell division have received little attention . by combining ultrastructural analyses and time - lapse microscopy ,
we ... |
studies have estimated that in 2014 , 360 million people worldwide had hearing disabilities , and hearing loss was the 13 greatest cause of disease burden measured as disability - adjusted life years ( dalys ) , with a dalys value of approximately 4 million years .
noise - induced hearing loss ( nihl ) is incurable ,... | background : complex noise and its relation to hearing loss are difficult to measure and evaluate . in complex noise measurement , individual exposure results
may not accurately represent lifetime noise exposure .
thus , the mean laeq,8 h values of individuals in the same workgroup were also used to represent laeq,... |
male breast cancer ( mbc ) is uncommon , accounting for < 1% of all cases.1 bilateral male breast cancer is very rare and in two large series was reported in only 0.2%2.7% of cases.2,3 it is recognized that hormonal , genetic , and environmental factors play a part in the pathogenesis of female breast cancer and also p... | synchronous bilateral male breast cancer ( mbc ) is rare and only a few cases have been reported in the literature .
the majority of mbc patients have no definable risk factors .
we describe a case with klinefelter s syndrome , prior thymic irradiation , testicular surgery , and first degree family history in a 61-... |
intensive care is expensive . in 2005 , critical care medicine represented 4% of all national health expenditures and 13.4% of hospital costs.(1 , 2 ) although health care is not deliberately rationed in the u.s .
, the cost and resource intensity of intensive care leads to ongoing debate about how to distribute it .... | objectiveto compare use of mechanical ventilation and hospital costs across ventilated patients of all ages , preterm through adults , in a nationally - representative sample.study designsecondary analysis of the 2009 agency for healthcare research and quality national inpatient sample.results1,107,563 ( 2.8% ) patient... |
this study was a prospective observational investigation using quantitative and qualitative questionnaires to survey patients and family members regarding their experiences while the patient was intubated and mechanically ventilated .
this investigation was conducted over a 6-month period in an icu , after review and... | backgroundsedation practices in an icu have shifted significantly in the past 20 years toward the use of minimizing sedation in mechanically ventilated patients .
while minimizing sedation is clearly in the best interest of patients , data are lacking about how this approach affects patients experiences.methodswe int... |
the chronic inflammatory bowel disease ( ibd ) , ulcerative colitis ( uc ) which is a diffuse process , involving the superficial mucosa of the colon is one of the common morbidities affecting many people throughout the world . although , the etiology of uc is unknown , genetic and environmental factors are thought to ... | background : pulmonary impairment in patients suffering ulcerative colitis ( uc ) has been suggested by several investigators using standard pulmonary function tests ( pfts ) .
this changes in pulmonary function associated with minimal respiratory symptoms have been documented , especially in patients with active dis... |
a 51-year - old female had palpitations and radiating back pain and underwent whole - aorta angio 3d computed tomography ( ct ) .
the ct revealed a horizontal axis right kidney with a 4.2 cm , lobulating contour multilocular cystic mass at the lower pole .
there were multiple irregular , enhancing septations with a... | the authors report a case of renal cell carcinoma in a right malrotated ( horizontal axis ) kidney .
the patient was treated by hand - assisted laparoscopic radical nephrectomy .
this is the first report of a horizontal axis malrotated kidney with renal cell carcinoma . |
the world health organization world alliance for patient safety has identified poor test result management as a priority patient safety area ( 1 ) .
poor test result follow - up can have major consequences for the quality of care , including missed diagnoses and suboptimal patient outcomes .
a root cause analysis ... | backgroundthe world health organization world alliance for patient safety has identified test result management as a priority area .
poor test result follow - up can have major consequences for the quality of care , including missed diagnoses and suboptimal patient outcomes . over the last three decades
there has ... |
growing investments in health research by both governments and charitable organisations have fuelled an increase in collaborative research projects between investigators from affluent and developing countries .
data sharing defined as the voluntary provision of information from one individual or institution to anot... | growing investments in health research by governments and charitable organizations have fueled an increase in collaborative research projects between investigators from affluent and developing countries .
current international guidelines are silent on common intra - consortium data - sharing issues that arise in the ... |
duloxetine is a selective serotonin and noradrenaline reuptake inhibitor ( snri ) , indicated for the treatment of major depressive disorder and diabetic peripheral neuropathy . in rare cases ,
thiazide diuretics are among the most commonly prescribed antihypertensive medications , which have been implicated in multi... | hyponatremia is a known adverse effect of duloxetine , and it can lead to potentially life - threatening complications .
administration of thiazide diuretics also has been the cause of hyponatremia .
we report a case of duloxetine - induced hyponatremia in an elderly patient treated with thiazide diuretics .
an 8... |
over the last three decades , our understanding of the pathophysiology , epidemiology , diagnosis , and treatment of clostridium difficile infection ( cdi ) has grown , notably as the incidence and severity of infections have increased dramatically.1 from 1935 , when first cultured by hall and otoole , until the 1970s ... | treatment options for clostridium difficile infection ( cdi ) remain limited despite this usually nosocomial infection posing an urgent threat to public health .
a major paradox of the management of cdi is the use of antimicrobial agents to treat infection , which runs the risk of prolonged gut microbiota perturbatio... |
copd is a global public health concern and is currently the third leading cause of death worldwide .
it is a common , complex , and heterogeneous condition , which is responsible for considerable and growing morbidity , mortality , and health care expenses worldwide.1,2 exacerbations of copd indicate instability or w... | backgroundthe major characteristic of copd is systemic inflammation . the parameters such as neutrophil - to - lymphocyte ratio ( nlr ) and eosinophil - to - basophil ratio ( ebr ) in routine blood test ( rbt ) are considered to be the underlying biomarkers of inflammation .
we hypothesized that the prognosis of pati... |
mercury ( hg ) contamination is an issue of global concern because numerous human activities release hg into the environment and increase its concentrations in many abiotic and biotic compartments ( 1 ) .
these increases are largely the result of hg emissions from mining , cement production , and the combustion of co... | in the mid-1990s , yellow perch ( perca flavescens ) and common loons ( gavia immer ) from kejimkujik national park and national historic site ( knpnhs ) , nova scotia , canada , had among the highest mercury ( hg ) concentrations across north america . in 2006 and 2007 ,
we re - examined 16 lakes to determine whethe... |
although bisphosphonate , a potent inhibitor of bone resorption , is generally safe and effective , it carries the potential risk of over - suppressing bone turnover .
a number of reports have been issued regarding insufficiency femoral fractures in patients on long - term bisphosphonate therapy , and recently severa... | a number of reports regarding atypical fractures of the femur have raised questions concerning the possible correlation between long - term bisphosphonate treatment and the occurrence of insufficiency fractures in the proximal femur . however , clinically , it is often confused whether is it a fatigue fracture because ... |
acute glomerulonephritis ( gn ) generally presents as a pentad of proteinuria , hematuria , edema , hypertension and elevated creatinine ( cr ) .
most cases of gn occur due to immunological response to various triggers such as infections , drugs , cancers or systemic diseases such as lupus . in most cancer patients r... | we report a previously unrecognized complication of severe acute kidney injury ( aki ) after the administration of pegfilgrastim with biopsy findings of mesangioproliferative glomerulonephritis ( gn ) and tubular necrosis .
a 51-year - old white female with a history of breast cancer presented to the hospital with na... |
about 0.6 to 4 newborn children per 1,000 suffer from spinal dysraphism ( sd ) .
this can be characterized by incomplete development of the central nervous system , which includes open ( myelocele and meningomyocele ) or closed ( lipoma , occult spina bifida , and dermal sinus ) entities . frequently , the above - me... | purposeanticholinergics are a key element in treating neurogenic detrusor overactivity , but only limited data are available in the pediatric population , thus limiting the application to children even for oxybutynin chloride ( oc ) , a prototype drug .
this retrospective study was designed to provide data regarding ... |
we conducted this population - based cohort study using data from medical registries in northern denmark over the period from 1998 to 2010 .
data were obtained from the clinical laboratory information system research database ( labka ) ( 20 ) , the aarhus university prescription database ( aupd ) ( 21 ) , the danish ... | backgrounda substantial proportion of patients referred for plasma vitamin b12 ( cobalamin [ cbl ] ) measurement present with high cbl levels , which have been reported in patients with different cancer types .
however , the cancer risk among patients with newly diagnosed high cbl levels has not been adequately exami... |
electronic cigarette ( e - cigarette ) usage has increased significantly since their introduction in 2003 . from 2009 to 2013 , adult usage increased from 0.6% to 15% . among adolescents ,
current , from 2011 to 2015 , e - cigarette use has increased from 1.5% to 16% . despite their popularity ,
research on these r... | purpose : the purpose of this study was to compare medical residents and practicing physicians in primary care specialties regarding their knowledge and beliefs about electronic cigarettes ( e - cigarettes ) .
we wanted to ascertain whether years removed from medical school had an effect on screening practices , reco... |
liver transplant has turned to an acceptable treatment option for patients with liver failure , although it was previously just an experimental operation conducted on patients with no hope of cure ( 1 ) . until 1980 , the possibility of living a year after liver transplantation was 30% or even less ( 2 ) , while presen... | introductionpregnancy and parenting have been part of human life throughout history and liver transplant recipients are not any exception .
this paper reports successful pregnancies in two liver transplant recipients in iran.case presentationthe first case was a 34-year old woman who had undergone orthotopic liver tr... |
pregnancy - associated thrombotic microangiopathy ( tma ) is a very rare condition ; however , it significantly increases fetal or maternal morbidity and mortality .
the first one is an acquired or genetic deficiency in adamts13 , a von willebrand factor - processing enzyme .
the other mechanism is mutations in one... | pregnancy - associated thrombotic microangiopathy is a very rare condition ; however , it significantly increases fetal or maternal morbidity and mortality .
pregnancy may trigger atypical hemolytic uremic syndrome ( ahus ) or thrombotic thrombocytopenic purpura .
the risk for pregnancy - associated ahus is highest... |
hemoptysis is bleeding originating from the lower airways ; it has a wide clinical spectrum that can reach life - threatening dimensions .
the most important causes of hemoptysis are bronchiectasis , chronic bronchitis , tuberculosis , and malignancy ( 1 ) .
etiological causes are usually investigated with chest ra... | management of cryptogenic massive hemoptysis is difficult , and conservative treatment may be inadequate to stop the hemorrhage .
surgery is not a reasonable option because there is no underlying identifiable pathology .
this study aimed to investigate the radiologic findings and bronchial artery embolization outco... |
since the 1990s , physical input - output tables ( piots ) that measure the deliveries of an industry in a single unit of mass have been compiled . in terms of appropriation of resources ( e.g. water , energy , land ) for final demand categories ,
the models based on piots are an alternative to the models based on or... | this paper addresses the question whether the results of input - output ( io ) impact analyses differ ( and to what extent ) when a framework in current prices or in constant prices is used .
we consider the effect of an exogenous stimulus of final demand in current prices on ( a ) gross output in constant prices , a... |
first isothermal sections at 700 and 900 c . mandatory improved isothermal section at 800 c .
while for low temperature soldering suitable materials have been found , e.g. sn ag cu and sn cu ni , no convenient alloy has so far been found for high - temperature soldering ( melting temperature 230 c ) . at the ... | in this work three complete isothermal sections of the ni
sn zn system at 700 , 800 and 900 c are presented .
they were constructed based on experimental investigation of more than 60 alloy samples .
powder xrd , single crystal xrd , epma , and dta measurements on selected samples were carried out .
two new t... |
group 1 consisted of 104 selected patients from our outpatient clinic with a definite diagnosis of ms according to the mcdonald criteria .
clinical selection criteria were as follows : relapses with severe or recurrent myelitis and/or one or more episodes of severe ( visual acuity < 0.5 ) on , and/or brainstem syndro... | objectives : to evaluate the presence of antibodies to conformation - intact myelin oligodendrocyte glycoprotein ( mog ) in a subgroup of adult patients with clinically definite multiple sclerosis ( ms ) preselected for a specific clinical phenotype including severe spinal cord , optic nerve , and brainstem involvement... |
chronic kidney disease ( ckd ) is a very common co - morbidity associated with congestive heart failure . often times , a large proportion of these patients have co - morbidities that can cause kidney dysfunction in addition to the pre renal effects of the poor systemic perfusion related to low cardiac output status . ... | backgroundthe goal of this study is to assess the effect of cardiac resynchronization therapy ( crt ) over time on renal function and its impact on mortality .
the effect of crt on renal function in patients with heart failure is not well understood.methodsall patients who underwent crt implantation at university of ... |
homocysteine ( hcy ) is a sulfhydryl amino acid derived from the metabolism of methionine , an essential amino acid .
it can be transsulfurated to cysteine through a pyridoxine - dependent pathway or remethylated to methionine through pathways that are dependent on folates , cobalamin and betaine .
hcy concentratio... | backgroundphysical exercise influences homocysteine ( hcy ) concentrations , cognitive function and the metabolic profile .
the purpose of this study was to investigate the influence of regular physical exercise on hcy levels , the metabolic profile and cognitive function in healthy elderly males before and after an ... |
liposomes , or phospholipid vesicles , are good models for biological membranes , which are found in all species from bacteria to mammals [ 1 - 3 ] .
phospholipids are anionic , cationic , or zwitterionic , and the polar head groups , such as choline , ethanolamine , and serine , differ from each other in size and ty... | this work demonstrates the synthesis and characterization of novel nanoporous silicified phospholipid bilayers assembled inorganic powders .
the materials are obtained by silicification process with silica precursor at the hydrophilic region of phospholipid bilayers .
this process involves the co - assembly of a ch... |
this follow - up study included 2,227 men and 3,205 women with baseline normal glucose tolerance ( ngt ) in the sdpp , a prospective population - based cohort described in detail elsewhere ( 12 ) . in brief , the sdpp baseline study group consists of 3,128 men and 4,821 women aged 3556 years , characterized in 19921994... | objectiveto investigate the prospective influence of work stress on type 2 diabetes ( t2d).research design and methodsthis population - based cohort included 3,205 women and 2,227 men , aged 3556 years , with baseline normal glucose tolerance measured with oral glucose tolerance test .
at follow - up 810 years later ... |
fiessinger - leroy 's disease is a rare multisystem autoimmune spondyloarthropathic disease , first described by hans reiter in 1916 in a prussian soldier , as reiter 's disease , and by ahvonen , sievers , and aho in 1969 as reactive arthritis with an incidence of 3.55/100,000 across the world .
it is characterize... | fiessinger - leroy 's disease ( reiter 's disease ) is rare and not commonly reported in india .
this paper reports a case of a 35-year - old male with fiessinger - leroy 's disease , occurring after balanitis .
the patient presented with symmetrical polyarthritis , pruritic scaly plaques , keratoderma blenorrhagic... |
since one can not sense oral malodor accurately by oneself , bad breath brings marked psychological discomfort and may interfere with social interactions .
many people feel anxiety or distress regarding oral malodor , even though they may have no such oral malodor .
they may believe they have oral malodor when they... | objectives .
even though objective data indicating the absence of oral malodor are presented to patients , they may be skeptical about the results , possibly due to the presence of some discomfort in the oral cavity .
the objective of this study was to investigate whether there is an association among self - percep... |
upper cervical fractures and dislocations account for 24% of cervical spine injuries,1 with the atlantoaxial region being the commonly involved site.2 subluxation and dislocation of the cervical spine in adults commonly occur at the highly mobile lower segments ( c4-c7).34 this is in contrast to the occurrence in child... | a 49-year - old male presented with neck pain and deformity following an industrial accident sustained two months back .
his neurology was normal except for a minimal weakness in left biceps ( grade 4/5 ) .
radiographs , magnetic resonance imaging and computed tomographic scan revealed fracture dislocation of c2-c3... |
spontaneous bacterial peritonitis ( sbp ) is a frequent and severe complication in patients with cirrhosis and ascites .
sbp is a bacterial infection that occurs in the absence of an evident intra - abdominal and surgically treatable source of infection , such as the perforation or inflammation of intra - abdominal o... | spontaneous bacterial peritonitis ( sbp ) is a frequent and severe complication in cirrhotic patients with ascites .
although identifying the pathogen(s ) plays a major role in the management of infectious diseases , ascitic fluid cultures often show negative results in patients with clinical signs and symptoms of sb... |
four differently tanned , unfinished leather samples ( all from cattle ) from normal production were received from three european tanneries .
all materials were tanned and post - tanned , but not coated and finished ( so - called crust leather ) .
detailed descriptions of general leather processing steps , always i... | backgroundapproximately 13% of the adult population in europe is allergic to chromium ( cr ) .
a new restriction in reach ( registration , evaluation , authorization and restriction of chemicals ) based on the iso 17075 standard has recently been adopted in the eu to limit cr(vi ) in consumer and occupational leather... |
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