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a 53 kg , 157 cm , 35-year - old primigravida at the 38th week of pregnancy was admitted for a cesarean section due to breech presentation .
computed tomographic angiography performed 3 years prior had revealed that the left common carotid artery and left subclavian artery were totally occluded along with a thromboti... | takayasu 's arteritis ( ta ) is a chronic inflammatory disease involving the aorta . because ta sometimes involves cerebral arteries , anesthetic debates focus on cerebral monitoring .
there is limited evidence as to which cerebral monitoring method is most adequate .
furthermore , there is insufficient evidence to... |
the advent of minimally invasive technique has changed the surgical approaches to management of both anterior and posterior segment disorders and provided the potential for performance of multiple surgical procedures in all ocular structures within the same operation , with prompt switching from one of the numerous ent... | purpose . to describe our technique , clear corneal phacovitrectomy with posterior capsulorhexis ( ccpv ) , for the management of selected posterior segment intraocular foreign body ( iofb ) , posteriorly dislocated lens fragments ( pdlf ) , and proliferative diabetic retinopathy ( pdr ) cases
. methods .
this was ... |
considerable effort has been dedicated over the last decade to developing focusing devices capable of delivering x - ray beams of micrometer and submicrometer size for a wide range of spectroscopic and diffraction applications ranging from materials science and environmental science to biomedical studies .
these effo... | a pre - focused x - ray beam has been used to illuminate a single - bounce capillary in order to generate a high - flux x - ray microbeam at the biocat undulator x - ray beamline at the advanced photon source .
the combined optical arrangement makes it suitable for many microprobe fluorescence applications and micro ... |
a recent study found 9.8% ( n = 41 ) of french bulldogs had compressive spinal cord disease associated with hemivertebra .
the most common clinical findings are pelvic limb ataxia and paresis ranging from very mild ataxia to loss of voluntary movement of the pelvic limbs .
the diagnosis is based on clinical signs... | this study follows the treatment of six french bulldogs with paraparesis caused by congenital hemivertebra which were structurally mild but clinically severe .
a standardized acupuncture ( zhn ji ) treatment using hua - tuo - jiaji ( htjj ) as local points and other distant points combined with chinese herbs improve... |
pediatric glaucoma includes a wide variety of conditions which result in elevated intraocular pressure and optic nerve damage , ranging from primary congenital glaucoma since birth to developmental glaucoma associated with other diseases and acquired glaucoma secondary to multiple causes .
depending on the age of the... | currently , there are numerous choices for the treatment of pediatric glaucoma depending on the type of glaucoma , the age of the patient , and other particularities of the condition discussed in this review .
traditionally , goniotomy and trabeculotomy ab externo have been the preferred choices of treatment for cong... |
the focus of this paper lies at the intersection of three strands of investigation , each of which has generated a substantial literature .
the first strand concerns the relationship between preferences for future childbearing and reproductive behaviour and the closely related topic of unmet need for contraception . ... | summarythere is now widespread agreement on the importance of men 's role in reproductive decision - making .
several studies have argued that fertility preferences and their translation into behaviour differ between polygamous and monogamous unions .
studies investigating the dominance of men 's preferences over w... |
for memory formation in a neuronal circuit , the primary function of presynaptic terminals is the firing activity - dependent release of neurotransmitters and subsequent recycling of their carrier synaptic vesicles , processes which critically depend on atp and ca .
presynaptic firing of action potentials activates v... | synaptic efficacy is remodeled by neuronal firing activity at the presynaptic terminal .
presynaptic activity - dependent changes in transmitter release induce postsynaptic plasticity , including morphological change in spine , gene transcription , and protein synthesis and trafficking .
the presynaptic transmitter... |
teeth can be moved through the alveolar bone when appropriate orthodontic force is applied to them .
this is mainly due to the fact that mechanical loading of a biological system results in strain , which subsequently leads to biological responses at the cellular and molecular level , aiming at adaptation of the syst... | orthodontic force elicits a biological response in the tissues surrounding the teeth , resulting in remodeling of the periodontal ligament and the alveolar bone . the force - induced tissue strain result in reorganization of both cellular and extracellular matrix , besides producing changes in the local vascularity .
... |
imitation is an innate tendency in humans ( meltzoff and moore , 1977 ; meltzoff and moore , 1983 ; meltzoff and moore , 1989 ) as well as in newborn chimpanzees ( bard and russell , 1999 ; myowa , 1996 ; myowa - yamakoshi et al . , 2005 ) and macaques ( ferrari et al . , 2006 )
the ability to reproduce gestures may ... | the ability to reproduce visually presented actions has been studied through neuropsychological observations of patients with ideomotor apraxia .
these studies include attempts to understand the neural basis of action reproduction based on lesion symptom mapping in different patient groups .
while there is a conve... |
anti - neutrophil cytoplasmic antibody ( anca)-positive vasculitis a term that is favored to designate the disease otherwise known as wegener 's granulomatosis is a rare multi - system disease that is classically described as consisting of necrotizing granulomas and vasculitis of the respiratory tract , generalized sm... | anti - neutrophil cytoplasmic antibody ( anca)-positive vasculitis the term recently applied to wegener 's granulomatosis is a rare multi - system inflammation characterized by necrotizing granulomas and vasculitis .
we investigated the ocular manifestations of this disease in a group of patients drawn from five in... |
we use bilamellar - invaginated vesicles ( bivs ) that are unique liposomal nanoparticles ( nps ) providing highly efficient delivery for intravenous ( iv ) injection of encapsulated therapeutics including plasmid dna [ 15 ] .
in addition to having extended half - life and stability in circulation , bivs are nontoxic... | intravenous injection of therapeutics is required to effectively treat or cure metastatic cancer , certain cardiovascular diseases , and other acquired or inherited diseases .
using this route of delivery allows potential uptake in all disease targets that are accessed by the bloodstream .
however , normal tissues ... |
the survival of children with osteosarcoma has improved substantially over the last 30 yr . however , as the number of long - term survivors has increased , there have been increasing concerns about the potential of late sequelae , especially in the development of second malignant neoplasms ( smn 's ) . in previous rep... | we report two cases of papillary thyroid carcinoma occurring after the successful treatment of osteosarcoma .
one of the patients was administered with several alkylating agents and topoisomerase ii inhibitor as part of the primary treatment of osteosarcoma .
the onset of thyroid carcinoma occurred after 5 and 12 y... |
nonmotor symptoms have a strong impact on the prognosis and quality of life in patients with multiple system atrophy ( msa ) . patients with msa often have evidence of compromised gastrointestinal motility [ 1 , 2 ] , which may be caused by disruptions in the autonomic nervous system .
however , it remains unclear wh... | patients with multiple system atrophy ( msa ) often have evidence of compromised gastrointestinal motility .
ghrelin is a gut hormone that influences gastrointestinal motility in humans .
the aim of this study was to determine whether ghrelin secretion is affected in msa patients , and to investigate the relation b... |
multiple alignments of nucleic acid and protein sequences are basic investigations widely used for a large number of studies , such as phylogeny , profile construction , structure prediction , and sequence / structure activity relationships . in the last years
, many programs and services have been developed to align... | multiple sequence alignments are successfully applied in many studies for understanding the structural and functional relations among single nucleic acids and protein sequences as well as whole families . because of the rapid growth of sequence databases , multiple sequence alignments can often be very large and diffic... |
the m+c program currently provides health insurance coverage to 5 million medicare beneficiaries through privately operated managed care plans ( centers for medicare & medicaid services , 2002b ) . in exchange for accepting some limits on utilization and choice of provider ,
m+c enrollees typically receive more exten... | over the last 2 years , medicare+choice ( m+c ) plans raised premiums and reduced benefits to an unprecedented degree , arguing that these were unavoidable consequences of inadequate payments .
we investigate plan premium and benefit decisions , taking advantage of a natural experiment to separate the influences of p... |
despite advances in care over the past 20 years , diabetic nephropathy ( dn ) remains the single largest cause of patients with diabetes , and additional therapeutic approaches beyond glycemic and hypertensive control should be employed to reduce the rate of progression of nephropathy .
multiple metabolic pathways ar... | glycosaminoglycans or sulodexide has shown benefits in early experimental diabetic nephropathy ( dn ) models , but its efficacy in patients with early stage of dn is unknown . methods .
twenty patients were randomly assigned to the placebo group and another 20 patients were randomly assigned to receive sulodexide 100... |
it is rare ad genetic disorder characterized by multiple exostosis , prevalence 1 in 30,000 , m : f radio is 1:5:1 with incomplete penetrance in female .
the presence of a painless mass around joints that slowly increases with age until puberty is suggestive of the diagnosis .
a 10-year - old boy presented with gen... | familial multiple exostosis in a family of seven members who are affected found that exostosis was arising both from bones of enchondral as well as membranous ossification , which was sessile as well as pedunculated and was larger in size at the growing ends of the bones .
the lesions occur only in bones that develop... |
congenital adrenal hyperplasia ( cah ; omim # 201910 ) is a group of autosomal recessive disorders that result from the deficiency of one of several enzymes involved in the steroidogenic pathway for cortisol biosynthesis . the most common cause of cah ,
accounting for 90% of cases , is 21-hydroxylase deficiency resul... | from 2007 to 2014 the new york state ( nys ) newborn screening ( nbs ) program screened 2 million newborns for congenital adrenal hyperplasia ( cah ) .
the data was analyzed to determine factors that affect 17-hydroxyprogesterone levels and assist in developing algorithm changes that would improve the positive predic... |
because this research was a part of a public health response , our study did not require formal ethical approval from a medical ethics committee .
we communicated with the airline and bus operators to collect passenger information and undertook personal interviews in related communities .
a hotline was set up , and... | confirmation of an imported case of infection with middle east respiratory syndrome coronavirus in china triggered intensive contact tracing and mandatory monitoring . using a hotline and surveillance video footage was effective for tracing all 110 identified contacts .
contact monitoring detected no secondary transm... |
the covalent binding of an ultimate carcinogen to the dna bases or phosphate groups creates a premutational lesion that in vivo is processed by the repair , replication and recombination enzymes , and eventually may be converted into a mutation .
being interested in the way that an initial premutational event is conv... | |
due to their wide band - gap and high exciton binding energy , zno and its alloys are of considerable interest for applications as optoelectronic devices , such as short - wavelength light - emitting diode ( led ) and laser diode ( ld ) .
especially , the band - gap of zn1xmgxo alloys can be tuned from 3.3 to 4.2 ev ... | the pt nanoparticles ( nps ) , which posses the wider tunable localized - surface - plasmon ( lsp ) energy varying from deep ultraviolet to visible region depending on their morphology , were prepared by annealing pt thin films with different initial mass - thicknesses .
a sixfold enhancement of the 357 nm forward em... |
warfarin is an oral anticoagulant widely used for the treatment of arterial and venous thromboembolism as well as for primary and secondary prevention of these disorders .
the most common indications for warfarin therapy are arterial fibrillation , venous and arterial thrombosis , systemic embolism , and mechanical h... | this paper presents the development and validation of a novel method for quantification of the oral anticoagulant drug warfarin in dried plasma spots ( dps ) by high - performance liquid chromatography with tandem mass spectrometry ( hplc - ms / ms ) .
blood plasma was chosen as a biological fluid to preclude the inf... |
type 1 diabetes mellitus ( t1 dm ) is a chronic medical condition requiring intensive treatment and optimal glycemic control in order to prevent and/or delay onset and/or progression of long term complications .
cardiovascular disease ( cvd ) is the major cause of death for patients with t1 dm in the united states . ... | background / objectives . endothelial dysfunction due to
hyperglycemia - induced oxidative damage is an important predictor of future cardiovascular risk in patients with type 1 diabetes mellitus ( t1 dm ) and is present in adolescent t1 dm . we hypothesized that combined treatment with the antioxidant vitamins c and... |
diabetic ketoacidosis ( dka ) is a metabolic derangement characterized by the triad of hyperglycemia , acidosis , and ketosis that occurs in the presence of very low levels of effective insulin action .
dka is a current threat for children with type 1 diabetes and its epidemiology is variable in various countries [ 1... | we conducted a retrospective survey in pediatric centers belonging to the italian society for pediatric diabetology and endocrinology .
the following data were collected for all new - onset diabetes patients aged 018 years : dka ( ph < 7.30 ) , severe dka ( ph < 7.1 ) , dka in preschool children , dka treatment accor... |
pennsylvania mandates that any medical event , involving the clinical care of a patient in a licensed acute care facility , that either results in an unanticipated injury ( serious event ) or could have injured the patient ( near - miss incident ) be reported to the pennsylvania patient safety authority .
pennsylvani... | the pennsylvania patient safety authority receives over 235,000 reports of medical error per year . near
miss and serious event reports of common and interesting problems are analysed to identify best practices for preventing harmful errors .
dissemination of this evidence - based information in the peer - reviewed... |
bisphosphonates ( bps ) are well - known substances with very efficient antiresorptive properties [ 1 , 2 ] .
therefore , bps have important effects on bone turnover and are widely used to treat a variety of diseases such as osteoporosis , bone metastasis , hypercalcemia of malignancy , paget s disease , osteogenesis... | bisphosphonates ( bps ) are well - known substances with very efficient antiresorptive properties
. their beneficial actions are useful not only in achieving better bone mineral density but also in improving bone microarchitecture , strength and , consequently , its quality .
surgical cement , being a polymer compo... |
heavy metals such as cadmium , lead , zinc , nickel , copper , and
chromium ( vi ) or their compounds have been used extensively by various metal finishing ,
mining , and chemical industries .
this has led to a sharp increasing in the
contamination of water . due to their toxicity
, the presence of these meta... | a new method of indirect determination of cu2 + was developed based on square - wave voltammetry by the oxidation of iodide in organic solvent at the liquid / liquid ( l / l ) interface .
the limit of detection for the determination of cu2 + in this method was found to be 5 104 mol / l , and the concentration ranged... |
with the introduction of cone - beam computed tomography ( cbct ) to dentistry as a valuable imaging modality , this modality is increasingly used since it can provide three dimensional ( 3d ) , high resolution accurate information of hard tissues with a relatively low radiation dose .
it enhances diagnosis , treatme... | objectives : the aim of this study was to assess the effect of tube current , kilovoltage peak ( kvp ) , metal type , and the position of metal objects on metal artifacts in cone - beam computed tomography ( cbct ) images.materials and methods : titanium and cobalt - chromium rods were fabricated and placed in a dry hu... |
one of the most reliable indicators of the malignancy of a pulmonary nodule is its growth rate [ 1 , 2 ] . to accurately measure the growth rate of a nodule
, automated methods need to repeatably and robustly measure the volume of a nodule on several scans .
juxtapleural pulmonary nodules are attached to the chest ... | an algorithm was developed to segment solid pulmonary nodules attached to the chest wall in computed
tomography scans . the pleural surface was estimated and used to segment the nodule from the
chest wall . to estimate the surface ,
a robust approach was used to identify points that lie on the pleural
surface b... |
to describe the pathophysiological findings of a patient with pemphigus vulgaris ( pv ) showing giant conjunctival papillae .
a 64-year - old man who had mucosal - dominant pv with giant conjunctival papillae , resembling those of vernal keratoconjunctivitis ( vkc ) , underwent an ophthalmological workup .
ophthalm... | purposeto describe the pathophysiological findings of a patient with pemphigus vulgaris ( pv ) showing giant conjunctival papillae.methodsa 64-year - old man who had mucosal - dominant pv with giant conjunctival papillae , resembling those of vernal keratoconjunctivitis ( vkc ) , underwent an ophthalmological workup . ... |
within the context of the technological advances of the 21st century , improper use of electronic media has become a major contributing factor to the growing problem of childhood obesity .
recent studies have shown a positive relation between time spent in front of tv and increasing adiposity among school children . ... | improper use of electronic media is considered a major contributing factor to childhood obesity . however ,
exergames , a new generation of active games , have made it possible to combine electronic entertainment with physical exercise .
the purpose of this systematic review was to analyze the use of exergaming as ... |
an axial chiral tetrachlorinated
bisbenzo[a]phenazine has been discovered that undergoes
an alkane - induced shift in the solid state from a disordered amorphous
form to an ordered polycrystalline form .
this phase transition is
caused by the formation of pores that accommodate linear alkanes of
varying len... | |
multiple myeloma ( mm ) is a neoplastic proliferation of plasma cells with overproduction of monoclonal immunoglobulins and infiltration into the bone and other organs
. the disease accounts for approximately 1% of all cancers and usually affects patients older than 60 years of age .
although ascites can develop in... | multiple myeloma ( mm ) is a neoplastic proliferation of plasma cells with overproduction of monoclonal immunoglobulins and infiltration into the bone and other organs .
ascites can develop in patients with lymphoproliferative and solid malignancies involving the peritoneum .
however , ascites is unusual in mm and ... |
there is a chance of indirect pulpal injury during restorative procedures47 . in cavities prepared to receive restorative materials , factors such as margin location , cavity depth and remaining sound tooth structure are important for a good prognosis . to avoid thermomechanical shortcomings ,
it has been recommended... | objective : the aim of this study was to assess the bond strength of indirect composite restorations cemented with a resin - based cement associated with etch - and - rinse and self - etching primer adhesive systems to dentin treated or not with a bioactive material.materials and method : twenty bovine incisor crowns h... |
the rate of childhood obesity is increasing in developing countries , but this rate is highest in the middle east . in the last few decades , the kingdom of saudi arabia ( ksa ) has experienced rapid socio - cultural changes caused by the dramatic rise in the economy of the arabian gulf region .
this transformation ,... | background : there is little information on the association between watching television ( tv ) and obesity in the arabian peninsula.aim of the study : the aim of this study was to explore the association between the watching of television and obesity in saudi children of school-age.materials and methods : a case - cont... |
proton therapy is now a well - established method in treatment of cancer and noncancer diseases .
the rationale of using protons with energies between 60 and 250 mev is based on the favourable depth dose distribution , so that the targets can be located on a spread - out bragg peak while the normal tissue is ex... | we measured the physical and radiobiological characteristics of 1 gev protons for possible applications in stereotactic radiosurgery ( image - guided plateau - proton radiosurgery ) .
a proton beam was accelerated at 1 gev at the brookhaven national laboratory ( upton , ny ) and a target in polymethyl methacrylate ... |
pregnancy is a physiological phenomenon with multidimensional processes including physical , social , physiological , cultural and mental aspects ( 1 ) .
the final goal of the parturition team is to provide a safe birth while maintaining the health of the mother and her neonate ( 3 ) . due to advancements in surgical... | backgrounda qualitative study was carried out on 200 pregnant women attending obstetric offices and imam ali women 's clinic in zahedan , iran during january 2010 to august 2011 .
twenty - nine focus group discussions ( fgds ) with 58 participants in each group were formed .
the study included women in the third tr... |
looking at the economical impact of antibiotic therapy of severe mrb infections , several factors were identified as the major cost drivers [ 3 - 5 ] : - prolonged hospital length of stay ( los ) - hours of mechanical ventilation ( hmv ) - duration of treatment on an intensive care unit ( icu ) - cost of patient isolat... | severe infections with multiresistant bacteria ( mrb ) are a medical challenge and a financial burden for hospitals .
the adequate antibiotic therapy is a key issue in multiresistant bacteria management .
several major cost drivers have been identified .
remarkably drug acquisition costs are not necessarily inclu... |
nontraumatic dental condition - related emergency department ( ed ) visits have increased substantially over time in the united states.13 information on the time of day and day of week that patients visit eds for nontraumatic dental conditions ( ntdcs ) is scanty and poorly documented .
ladrillo et al4 reported that ... | objectiveto determine whether the rates of nontraumatic dental condition ( ntdc)-related emergency department ( ed ) visits are higher during the typical working hours of dental offices and lower during night hours , as well as the associated factors.methodswe analyzed data from the national hospital ambulatory medical... |
a 37-year - old female with retroviral disease was brought to casualty by caregivers because she was confused .
she had started antiretroviral drugs 2 months earlier and subsequently defaulted . on initial clinical examination , the patient was confused ( not orientated to time , place , or person ) , pyrexial , and ... | a 37-year - old female presented confused with a preceding history of severe headache .
after clinical examination and investigations , she was diagnosed with disseminated tuberculosis ( including central nervous system involvement ) , and human immunodeficiency virus / acquired immune deficiency syndrome .
her hos... |
hysterectomy is the second most frequently performed major surgical procedure on women all over the world , next only to cesarean .
the term hysterectomy though means removal of uterus ; in practice it has a much wider classification depending upon the indication . at times , it is done without removal of the cervi... | background .
the idea of laparoscopic assisted vaginal hysterectomy ( lavh ) is to convert a potential abdominal hysterectomy to a vaginal one , thus decreasing associated morbidity and hastening recovery .
we compared intraoperative and postoperative outcomes between lavh and abdominal hysterectomy , to find out i... |
it has been practiced by tamil vaithiyars ( native healers of tamil nadu ) who taught people an impeccable life style that trails in societies of tamil nadu .
the current accepted modern medicine has gradually developed over the years by scientific and observational efforts of scientists .
the scientist paracelsus ... | pra cantirotaya centram ( pcc ) , a herbometallic formulation of siddha medicine , consists of mercury , sulphur , and gold , processed with red cotton flower and plantain stem pith juices . to evaluate its safety , acute and 28-day repeated oral toxicity studies
were performed following oecd test guidelines 423 and ... |
a previous report suggested that the spetzler - martin grading scale can not accurately predict microsurgical outcomes for avms located in the cerebellum.2 ) lawton et al . described the supplementary grading scale , which accounts for patient age , history of avm rupture , and compactness of the nidus.1 )
we report ... | the recently described supplementary grading scale may be superior to the widely used spetzler - martin grading scale in the prediction of microsurgical outcomes for cerebellar arteriovenous malformations ( avm ) .
we report two cases of ruptured cerebellar avms with the same spetzler - martin grade but different sup... |
capecitabine ( xeloda ) is an orally administered antineoplastic pro - drug , which in tumour tissue is preferentially converted to 5-fluorouracil ( 5-fu ) by thymidine phosphorylase ( tp ) . it is used as adjuvant chemotherapy for metastatic breast and colon cancer .
common dose - limiting side - effects of capecita... | we report the case of a 37-year - old woman ( phototype ii ) who presented at our outpatient clinic with a two - month history of hyperpigmented plantar macules .
medical history revealed that the patient had taken capecitabine in the past three months as adjuvant chemotherapy for recurrent breast cancer .
dermosco... |
the canadian medical association ( cma ) has published guidelines ( now in its 8 edition ) to assist physicians with the assessment of driving capacity .
the guidelines state that moderate - to - severe dementia is a contraindication to driving .
the cma uses the third canadian consensus conference on dementia guid... | backgroundthe assessment of fitness to drive in patients with cognitive impairment is complex .
the simard md was developed to assist with assessing fitness to drive . this study compares the clinical decision made by a geriatrician regarding driving with the simard md score.methodspatients with a diagnosis of mild d... |
congenital mesoblastic nephroma ( cmn ) was first described in 1967 by bolande et al .
it is the most commonly occurring renal tumor found in infants less than three months old , and known to have a favorable outcome after complete surgical excision ( 2 ) .
( 3 ) summarized the main pathological variants of cmn as ... | congenital mesoblastic nephroma ( cmn ) is the most common renal tumor in the first year of life . here , we present unique findings of cellular variant cmn seen on prenatal and postnatal mri with diffusion - weighted imaging ( dwi).the mass was well - visualized on prenatal mr dwi with diffusion restriction in the sol... |
the samples were nursing students from first to fourth year of education in isfahan faculty of nursing and midwifery who did patients care during clinical internship .
the interviews were carried out in the presence of the researcher and participant in a single room .
each session of interview lasted between 30 to ... | background : infectious disease control is one of the important components of patient care which can assist in reducing morbidity and mortality . source isolation is one of the strategies that have used in order to prevent from the spread of contagious infectious diseases . since nursing student should be able to do th... |
simkania negevensis is an obligate intracellular gram - negative bacterium belonging to the family of simkaniaceae in the order chlamydiales , discovered as a contaminant in a variety of cell cultures , and is able to grow also in various environmental free - living amoebae such as acanthamoeba poliphaga .
epidemiolo... | the in vitro activity of six cathelicidin peptides against the reference strain z of simkania negevensis was investigated .
five peptides
pg-1 , bac7 , smap-29 , bmap-27 , and bmap-28proved to be active at very low concentrations ( 1 to 0.1 g / ml ) , while ll-37 cathelicidin was ineffective even at a concentratio... |
one of the most common injuries during the growing age of an individual is dento - alveolar injuries .
although the oral region comprises 1% of total body area , the oral injuries account for as much as 5% of all body injuries , with an even higher proportion of oral injuries among children .
a traumatic dental inj... | objectives : traumatic dento - alveolar injuries are frequent in children and adolescents , affecting teeth , their supporting structures , and adjacent soft tissues .
because school teachers are likely to be in contact with the child soon after injury , it is important to ascertain their knowledge and attitude about... |
each student learns in different ways and this affects their performance . in medicine , students and teachers must update themselves and find appropriate ways for learning ( 1 ) . in such situations learning styles can help them improve their learning ability ( 2 ) .
teacher - based strategies can change to student ... | background : identifying and employing appropriate learning styles could play an important role in selecting teaching styles in order to improve education.objectives:this study aimed to determine the relationship between learning styles preferences and gender , educational major and status in first year students at isf... |
alzheimer 's disease ( ad ) is the leading cause of dementia in older adults .
currently 4.5 million americans have ad and this number is expected to rise to 13.2 million by the year 2050 .
estimates within canada suggest that over half a million individuals over 65 years of age have ad or a related disease [ 2 , 3... | alzheimer 's disease is the leading cause of dementia in older adults .
although memory problems are the most characteristic symptom of this disorder , many individuals also experience progressive problems with communication .
this systematic review investigates the effectiveness of methods to improve the verbal co... |
glycosylation is the most common co- and post - translational modification
of proteins ; it may be estimated that approximately 70% of cytosolic
and 80% of membrane - bound human proteins are glycosylated .
glycans play an important role in many different processes ( e.g. ,
viral infection , cancer development ... | impedimetric lectin biosensors capable
of recognizing two different
carbohydrates ( galactose and sialic acid ) in glycans attached to antibodies
isolated from human serum were prepared .
the first step entailed the
modification of a gold surface by a self - assembled monolayer ( sam )
deposited from a solu... |
multiple sclerosis ( ms ) is the most common neurological disease of young adults with over one million individuals worldwide afflicted by the disease ( noseworthy et al . , 2000 ;
ms is an inflammatory disease of the central nervous system ( cns ) that causes the demyelination of nerve cells and destroys oligodendro... | a growing body of evidence suggests that autoreactive cd8 t cells contribute to the disease process in multiple sclerosis ( ms ) .
lymphocytes in ms plaques are biased toward the cd8 lineage , and ms patients harbor cd8 t cells specific for multiple central nervous system ( cns ) antigens . currently , there are rela... |
haematopoiesis is a lifelong process that generates the range of blood cell types that exhibit distinct and specialised functions .
transcription factors play a critical role in this complex and highly orchestrated process , directing multipotent haematopoietic stem cells ( hscs ) towards lineage commitment by regula... | the ets family transcription factor pu.1 is a key regulator of haematopoietic differentiation .
its expression is dynamically controlled throughout haematopoiesis in order to direct appropriate lineage specification .
elucidating the biological role of pu.1 has proved challenging .
this paper will discuss how a r... |
this study aimed to ascertain whether medical students would enter a closed area where there was a raging epidemic of an infectious disease with a high fatality rate , and includes reasons for the students entering or refusing to enter .
participants included 50 second - year medical students .
they were assigned t... | |
with rapid economic development and industrialization , the construction industry continues to rank among the most hazardous industries in the world ( 1 ) . within the construction industry ,
the risk of a fatality is five times more than in manufacturing , whilst the risk of a major injury is two and a half times hi... | abstractbackgroundwith rapid economic development and industrialization , the construction industry continues to rank among the most hazardous industries in the world .
therefore , construction safety is always a significant concern for both practitioners and researchers .
the objective of this study was to create ... |
this study was a retrospective cohort study , using anonymized longitudinal data for all patients attending the south east london diabetic eye screening service between 2008 and 2011 .
the service evaluation was approved by the national health service ( nhs ) research and development office for south london ; informe... | objectiveannual diabetic eye screening has been implemented in england since 2008 .
this study aimed to estimate changes in the detection of retinopathy in the first 4 years of the program.research design and methodsparticipants included 32,340 patients with type 2 diabetes resident in three london boroughs with one ... |
despite great progresses in orthopaedics , cartilage defects still constitute a major medical issue leading to serious decrease in the quality of life and to high medical costs .
this is mainly due to the fact that articular cartilage is a tissue subject to intensive wear but endowed with modest regeneration potentia... | this paper provides an analytical characterization of chitosan scaffolds obtained by freeze - gelation toward the uptake and the controlled release of chondroitin sulphate ( cs ) , as cartilage repair agent , under different ph conditions . scanning electron microscopy ( sem ) ,
attenuated total reflectance - fourier... |
isolated para - aortic lymph node ( ln ) recurrence is defined as recurrence only to the para - aortic lns , and is a type of oligometastatic cancer .
this type of recurrence is relatively rare ; isolated para - aortic ln recurrence develops in approximately 12% of pelvic cancer patients following curative treatment ... | the purpose of this study was to evaluate the outcome of definitive three - dimensional conformal radiotherapy ( rt ) for isolated para - aortic lymph node ( ln ) recurrence in patients with controlled primary cancer of the pelvis .
twenty - four consecutive patients with isolated para - aortic ln recurrence were ret... |
a jejunal nodular mass was identified in an aging rat .
histologically , the boundaries between the lesion and surrounding normal tissue as well as between the inner circular muscle and outer longitudinal muscle were indistinct .
the lesion consisted of abundant eosinophilic matrix and cells with a large round to o... | |
brown norway rats weighing 200 to 250 g were purchased from samtako ( osan , korea ) .
care , use , and treatment of all animals in this study were in strict compliance with the association for research in vision and ophthalmology statement for the use of animals in ophthalmic and vision research .
animals were sub... | purposeto evaluate the inhibitory effect of chlorogenic acid on laser - induced choroidal neovascularization ( cnv ) in a rat model.methodsintraperitoneal injection of chlorogenic acid ( 10 mg / kg ) was inititated one day prior to laser photocoagulation and continued for eight days .
eyes were removed 14 days after ... |
the average age and life expectancy have increased in korea due to the aging of the society .
it is important to select an adequate treatment option considering patient age , level of activity , lower extremity alignment , and body mass index2,3 ) .
proximal tibial osteotomy has been used to treat knee joint degene... | purposeto evaluate the radiologic and functional outcomes of medial open wedge high tibial osteotomy ( hto ) combined with arthroscopic procedure in patients with medial osteoarthritis.materials and methodsfrom june 1996 to march 2010 , 26 patients ( 32 knees ) who underwent medial open wedge osteotomy and arthroscopic... |
nowadays , the body mass index ( bmi ) is increasing in many populations and childhood obesity is an emerging problem [ 13 ] . in the united states the prevalence rates of obesity between 1971 and 1974 in 611-year - old white / black children were 4% . between 1999 and 2002
, these prevalence rates increased to 13% a... | background . in view of the alarming incidence of obesity in children ,
insight into the epidemiology of the prediabetic state insulin resistance ( ir ) seems important .
therefore , the aim of this systematic review was to give an overview of all population - based studies reporting on the prevalence and incidence... |
in a population - based investigation in the united states , radhakrishnan et al demonstrated an annual incidence of 83 per 100,000 for any cervical radiculopathy ; a total of 561 individuals with cervical radiculopathy were studied.1 c8 was implicated in 35 cases ( 6.2% ) , making it the least frequently involved root... | study design questionnaire .
objective to evaluate the ability of spine surgeons to distinguish c8t1 radiculopathies from ulnar neuropathy .
methods twenty - four self - rated experienced cervical spine surgeons completed a questionnaire with the following items .
( 1 ) if the ulnar nerve is cut at the elbow... |
bladder cancer ( bc ) is the eighth most common cancer in korean men . at the time of diagnosis , the majority of bcs are nonmuscle invasive bladder cancers ( nmibcs ) , with the remainder being muscle invasive bladder cancers ( mibcs ) and metastatic disease .
although these cancer types originate from the same tran... | purposetopoisomerase - ii alpha ( topoiia ) , a dna gyrase isoform that plays an important role in the cell cycle , is present in normal tissues and various human cancers , and can show altered expression in both .
the aim of the current study was to examine the value of urinary topoiia cell - free dna as a noninvasi... |
fiberoptic endoscopes are the most commonly used instruments to evaluate colonic pathology in modern day practice .
the procedure is considered to be safe but complications such as bleeding and perforation , although rare may occur and may even be lethal especially in cases of late detection .
intraperitoneal perfo... | a 70 year old lady presented to the emergency department complaining of bubbling neck and abdominal discomfort .
she underwent diagnostic colonoscopy six hours before admission .
clinical examination showed a haemodynamically stable patient and imaging revealed free air in all body compartments .
we report a rar... |
comprehensive pulmonary rehabilitation improves exercise performance and health - related quality of life and reduces the frequency of hospitalization and health care costs . in exercise testing methods , bicycles , treadmills , and/or simple
potential outcome measurements include the maximum workload , maximum oxyge... | introduction : gait speed provides an integrated index of physical performance ; changes in gait speed could reflect deterioration in the underlying medical disorder or a response to medical / surgical interventions .
slower gait speeds reflect the overall level of impairment , especially in patients with chronic lun... |
since the aquatic environment serves as the ultimate sink for many environmental pollutants such as endocrine disrupting chemicals ( edcs ) , particular attention has been given to evaluate the ecological effects of edcs ( a wide variety of developmental , morphological and reproductive abnormalities : feminization or ... | objectivesin order to identify the possibility of striped bitterling ( sb ) ( acheilognathus yamatsutae ) being used as a test species for estrogenic endocrine disrupting chemicals ( eedcs ) , we carried out the cloning and sequence characterization of the estrogen receptor ( er).methodsthe er from a striped bitterling... |
this cross - sectional study design utilized a single center prospective convenience sample of patients ( 12 years of age and older ) presenting to the emergency department .
this is a community teaching hospital with 410 beds and 85,000 visits per year including more than 25,000 trauma cases per year .
power analy... | backgroundemergency physicians see many people who present to the emergency department stating that they are immunized against tetanus , when in fact , they are not . the patient history is not dependable for determining true tetanus status and simple patient surveys do not provide actual prevalence .
the objective o... |
dynamic steady state aerobic exercise lasting between 5 and 30 minutes is associated with an increase in cardiac output secondary to an increase in heart rate and stroke volume .
the heightened stroke volume is due , in part , to a starling - mediated increase in end - diastolic volume ( i.e. preload reserve ) and to... | backgroundthe effect of prolonged strenuous exercise ( pse ) on left ventricular ( lv ) systolic function has not been well studied in younger female triathletes .
this study examined lv systolic function prior to , during and immediately following pse ( i.e. , 40 km bicycle time trial followed by a 10 km run ) in 13... |
emergency thoracotomy is defined as the thoracotomy performed in the scene of accident , emergency department for patients arriving in extremis or in the operating room with no previous plan .
current indications are severe penetrating or blunt injury with recent witnessed loss of signs of life ( sol ) and persistent... | introduction and aim : emergency thoracotomy is performed either immediately at the scene of injury , in the emergency department or in the operating room .
it aims to evacuate the pericardial tamponade , control the haemorrhage , to ease the open cardiac massage and to cross - clamp the descending thoracic aorta to ... |
anorexia nervosa ( an ) is a psychiatric disorder which can result in life - threatening medical complications ( 1 - 3 ) and multifaceted endocrine abnormalities ( 4,5 ) .
its prevalence is 0.2 - 0.9% among young women , with a peak age ranging between 14 and 25 years ( 1 ) .
however , a significant number of middl... | anorexia nervosa ( an ) is a serious psychiatric disorder which typically occurs in young women ; however , more and more cases in middle - aged women are being reported .
the management of this complex disease requires a team approach , and full recovery occurs only in 50% of patients .
endocrine and metabolic com... |
now - a - days , obesity is considered to be epidemic disease which leads toward a positive energy balance .
it is associated with many health - related complications such as insulin resistance , type-2 diabetes mellitus ( t2 dm ) , and other metabolic disorders . in obese individuals , the accumulation of more
fat... | background : the aim of the present study was to investigate , anti - obesity effect of aloe vera ( av ) , and gymnema sylvestre ( gs ) whole extract powders administration to high - fat diet ( hfd ) fed c57bl/6j mice for 12 weeks.materials and methods : at the end of experiment , different parameters such as body weig... |
the combination of brachytherapy and external beam radiotherapy ( ebrt ) is a standard therapeutic option for high risk prostate cancer and has provided excellent results in such patients [ 1 , 2 ] .
brachytherapy allows a high dose of radiation to be administered directly into the prostate with a rapid fall off of a... | purposethe purpose of this study was to evaluate the impact of intraoperative mri / trus fusion procedure in ct3a prostate cancer patients treated with high - dose - rate ( hdr ) real - time brachytherapy.material and methodsprostate gland , dominant intraprostatic lesions ( dils ) , and extracapsular extension ( ece )... |
as chemically reactive molecules , reactive oxygen species ( ros ) including free radicals ( superoxide and hydroxyl radicals ) and nonradical species ( hydrogen peroxide ) can be produced at various conditions in a multitude of ways .
it has been proven that excessive ros production is responsible for inflammatory a... | abstractfree radical toxicity due to poorly maintained cellular redox levels is crucial events that have been associated with the pathogenesis of guillain barre syndrome ( gbs ) patients .
uric acid ( ua ) and albumin correlate with oxidative stress in some degree .
we aimed to evaluate the relationship between gb... |
pulmonary hypertension is characterized by elevated pulmonary arterial pressure and possible subsequent secondary right ventricular failure .
patients with pulmonary hypertension may initially complain of dyspnea upon exertion , lethargy , and fatigue .
as the disease progresses , right ventricular failure develops... | pulmonary hypertension is characterized by elevated pulmonary arterial pressure and secondary right ventricular failure . a thromboembolic occlusion of the proximal or distal pulmonary vasculature results in chronic thromboembolic pulmonary hypertension .
we report an uncommon case that presented to our hospital with... |
gram - negative bacteria are ubiquitous in marine environments . as in the case of other microrganisms from sea habitats , they represent an interesting field of research , being a valuable source of natural substances provided with powerful bioactivity . among the compounds that marine bacteria are able to synthesize ... | marine bacteria are microrganisms that have adapted , through millions of years , to survival in environments often characterized by one or more extreme physical or chemical parameters , namely pressure , temperature and salinity .
the main interest in the research on marine bacteria is due to their ability to produc... |
a toxic substance is a small molecule , peptide , or protein that is capable of causing injury or death .
toxins , both natural and man - made , represent an important class of poisonous compounds that are ubiquitous in nature , in homes and in the workplace .
common toxins include pollutants , pesticides , preserv... | in an effort to capture meaningful biological , chemical and mechanistic information about clinically relevant , commonly encountered or important toxins , we have developed the toxin and toxin - target database ( t3db ) .
the t3db is a unique bioinformatics resource that compiles comprehensive information about comm... |
intestinal transplantation ( itx ) has added a new dimension to the management of patients with irreversible intestinal and parenteral nutrition failure .
a good measure of its success not only involves having a patient alive , well and off parenteral nutrition ( pn ) , but having a patient that is nutritionally repl... | the objective of this study is to valuate two biomarkers that may guide nutritional assessment during follow up after intestinal transplantation .
we performed a retrospective study on prospectively collected data of insulin - like growth factor-1 ( igf-1 ) and effluent calprotectin in patients undergoing intestinal ... |
the pathogenesis of aortic stenosis ( as ) is a largely understudied research area , compared to other cardiovascular diseases , which has major human health implications .
historically , as has been considered an age - related , passive , degenerative disease . however , during the past 15 years , indisputable evide... | the study aimed to identify mechanosensitive pathways and gene networks that are stimulated by elevated cyclic pressure in aortic valve interstitial cells ( vics ) and lead to detrimental tissue remodeling and/or pathogenesis .
porcine aortic valve leaflets were exposed to cyclic pressures of 80 or 120 mmhg , corres... |
the modern treatment of pediatric type 1 diabetes mellitus ( t1d ) relies not only on professional medical care but also on psychosocial support .
the impact of t1d on everyday life is much broader than a mere adaptation to the demanding treatment regime ( balanced diet , blood glucose monitoring , insulin injections... | type 1 diabetes ( t1d ) in children and adolescents is relatively often accompanied by other immunopathological diseases , autoimmune thyroid disease ( aitd ) or celiac disease ( cd ) .
our aim was to assess whether these conditions are associated with changes in the health - related quality of life ( hrqol ) in pedi... |
aurora kinases , a family of three serine - threonine
kinases designated
a , b , and c , play key and distinct roles in different stages of mitosis . at the early stages of mitosis , aurora - a forms a complex with tpx2
( targeting protein for xklp2 ) that regulates centrosome maturation
and mitotic spindle ass... | optimization of the imidazo[4,5-b]pyridine - based
series of aurora kinase inhibitors led to the identification of 6-chloro-7-(4-(4-chlorobenzyl)piperazin-1-yl)-2-(1,3-dimethyl-1h - pyrazol-4-yl)-3h - imidazo[4,5-b]pyridine ( 27e ) , a potent inhibitor of aurora
kinases ( aurora - a kd = 7.5 nm , aurora - b kd = 48... |
musa acuminata ( banana ) is one of the most important fruit crops of world as well as of india .
banana could be considered poor man 's apple , and it is the cheapest among all other fruits in the country .
the pathogen is soil - borne and remains viable up to several years and cause 20%80% loss of banana .
seve... | the aim of the present study was to scrutinize the response of banana ( grand naine variety ) plants when interacting with dead or live pathogen , fusarium oxysporum f.sp .
cubense , a causative agent of panama disease .
response of plants was evaluated in terms of induction of defense - related marker enzyme activ... |
in the past few decades we have experienced dramatic changes in the age structure of human populations , especially in industrialized countries .
these changes are characterized by an increasing probability of reaching old and very old age.13 as a multidimensional reality of life , aging is difficult to define simply... | background : gerontological research aims at understanding factors that are crucial for mediating successful aging .
this term denotes the absence of significant disease and disabilities , maintenance of high levels of physical and cognitive function , and preservation of social and productive activities .
preser... |
a 19-year - old male presented with an additional opening on the ventral surface of the penile shaft along with a normally placed urethral meatus at the tip of the glans .
there was no history of swelling or stone impaction at the site of the opening .
the only surgical history was of a ceremonial circumcision at t... | isolated congenital urethrocutaneous fistula of the anterior urethra is an extremely rare anomaly in which , along with a normal urethra and meatus , a fistula is present .
these cases usually present in the pediatric age group .
to date , only one such case has been described in the adult population .
we describ... |
gastric bezoar is not a common disease ; however , it may become the reason for an intraluminal obstruction .
non - operative management of gastric bezoar such as medication and endoscopic fragmentation and retrieval has been proposed for treatment.(1,2 ) if these treatments fail , surgical approach is needed and rem... | regarding the removal of a gastric bezoar , laparoscopic surgery was performed and it was shown that the laparoscopic approach is safe and feasible .
however , the laparoscopic method has the risk of intraabdominal contamination , when the gastric bezoar is retrieved from the gastric lumen in the peritoneal cavity . ... |
pleural tuberculosis ( tb ) is one of the most important and common causes of pleural effusion , especially in the regions with high prevalence . nevertheless , the establishment of tuberculous pleural effusion ( tpe ) diagnosis is difficult and challenging .
traditionally , it is based on the isolation of mycobacter... | abstractbackground : the diagnosis of tuberculous pleurisy is difficult and traditional methods are not always helpful .
many studies have focused on the tumor necrosis factor - alpha ( tnf- ) assay in pleural effusion for the diagnosis of tuberculous pleurisy , but the results remain controversial . this meta - anal... |
progress of human civilization depends on the literacy and development in the lower levels of society .
any activity based on systematic thinking and practical approach requires its simple concept of literacy . in the past
, literacy was known as being capable of reading , writing and arithmetic , but in the presen... | background : the ability to access , analyze , evaluate , and convey information in various forms of media including print and nonprint requires media literacy , but the capacity to obtain , process , and understand basic information and services needed for appropriate decisions regarding health , considered an importa... |
electron capture dissociation ( ecd ) is a radical - driven fragmentation technique which provides an alternative to slow - heating collision induced dissociation ( cid).(1 ) ecd has successfully been applied to the small - scale detailed characterization of various peptides , modified or otherwise .
these experiment... | large data sets of electron capture dissociation ( ecd ) mass spectra from proteomic experiments are rich in information ; however , extracting that information in an optimal manner is not straightforward .
protein database search engines currently available are designed for low resolution cid data , from which fouri... |
an 18-day - old baby with failure to thrive was referred to
our clinic for eye examination .
blood
investigations included total and differential blood count ,
blood sugar , serum electrolytes , serum ammonia , serum
lactate , serum pyruvate , liver enzymes , thyroid function tests
and arterial blood gases ... | we describe a case of neurotrophic keratitis in association
with dihydroxypyrimidine dehydrogenase ( dhpd ) deficiency .
ocular manifestations in patients with dhpd are rare and
neurotrophic keratitis has never been reported before . a six - year-
old boy who was a known case of dhpd deficiency and born
of a ... |
asthma is a chronic inflammatory disease that causes airflow limitation and affects the performance of activities of daily living.1 pharmacological treatment is essential2 and is aimed at achieving and maintaining clinical asthma control.1 inhalation is the most widely used approach for the treatment of asthma because ... | abstractobjective : to validate two scores quantifying the ability of patients to use metered dose inhalers ( mdis ) or dry powder inhalers ( dpis ) ; to identify the most common errors made during their use ; and to identify the patients in need of an educational program for the use of these devices .
methods : this... |
among infectious diseases , hepatitis c virus ( hcv ) still represents a major public health threat , with a dramatic burden from both epidemiological and clinical points of view .
chronically infected individuals are estimated to reach 150170 million worldwide and estimates of incidence , performed in the united sta... | hepatitis c virus ( hcv ) still represents a major public health threat , with a dramatic burden from both epidemiological and clinical points of view .
new generation of direct - acting antiviral agents ( daas ) has been recently introduced in clinical practice promising to cure hcv and to overcome the issues relate... |
ambras syndrome ( as ) is a rare and special form of congenital hypertrichosis , associated with dysmorphic facial features and a familial pattern of inheritance .
it was first reported in 1993 by baumeister et al . till date , only ten cases of as are reported according to literature , of which two cases were associ... | ambras syndrome is a rare and special form of congenital hypertrichosis , characterized by dysmorphic facial features and familial pattern of inheritance .
it is rarely associated with gingival hyperplasia .
we report such a rare entity in a 38-year - old female patient with a history of consanguinity and positive ... |
intracranial atherosclerotic disease ( icad ) is the process by which atherosclerotic plaques affect large intracranial arteries .
intracranial stenosis represents the most advanced stage of icad and is a precursor to ischemic stroke .
icad is the leading cause of stroke among patients of asian ancestry , and hispa... | intracranial atherosclerotic disease ( icad ) is a major cause of ischemic stroke worldwide and represents a significant health problem .
the pathogenesis and natural history of icad are poorly understood , and rigorous treatment paradigms do not exist as they do for extracranial atherosclerosis . currently , the b... |
analysis of uncultured fetal cells by fluorescence in situ hybridization ( fish ) has been used as a rapid alternative in screening for common chromosomal aneuploidies ( 1 , 2 ) .
although fish usually takes only 24 to 48 hr , it is expensive and intensively laborious . recently
, quantitative fluorescent pcr ( qf ... | rapid prenatal diagnosis of common chromosome aneuploidies have been successful through quantitative fluoresent pcr ( qf - pcr ) assays and small tandem repeat ( str ) markers .
the purpose of our study was to investigate the clinical feasibility for rapid prenatal detection of down syndrome using the quantitative fl... |
congenital facial nerve palsy is clinically defined as unilateral or bilateral paralysis of facial nerve in neonatal period .
facial nerve aplasia is an extremely rare anomaly that usually occurs in association with moebius syndrome .
even rarer is the occurrence of isolated aplasia of facial nerve , with only few ... | we report two infants presenting with unilateral congenital facial palsy since birth . magnetic resonance imaging ( mri ) in both the cases revealed complete unilateral aplasia of facial nerve . to our knowledge , this is the first reported mr depiction of nonsyndromic isolated facial nerve aplasia .
imaging features... |
hospital overcapacity rates and emergency department ( ed ) waiting times are important issues currently being faced by the canadian medical system .
there is increasing pressure to reduce health - care costs and diminish unnecessary hospital admissions and ed visits .
of particular concern are social admissions , ... | backgroundolder adults are sometimes hospitalized with the admission diagnosis of failure to thrive ( ftt ) , often because they are not felt safe to be discharged back to their current living arrangement .
it is unclear if this diagnosis indicates primarily a social admission or suggests an acute medical deteriorati... |
carotid sinus hypersensitivity ( csh ) is characterized by an asystolic or hypotensive response to carotid sinus massage ( csm ) and is associated with syncope , unexplained falls , and drop attacks in older individuals .
csh is rare before the age of 40 years , but is diagnosed with increasing frequency with advanci... | backgroundcarotid sinus hypersensitivity ( csh ) is associated with syncope , unexplained falls , and drop attacks in older people but occurs asymptomatically in 35% of communitydwelling elders .
we hypothesized that impaired cerebral autoregulation is associated with the conversion of asymptomatic csh to symptomatic... |
cayler cardio - facial syndrome is a rare syndrome associated with asymmetric crying faces with congenital heart disease .
we report a newborn that was diagnosed as case of cayler cardio - facial syndrome based on clinical features and was confirmed with fish analysis .
a term male baby , born to non - consanguineo... | introduction : cayler cardio - facial syndrome is a rare syndrome associated with asymmetric crying faces with congenital heart disease . we report a newborn that was diagnosed as case of cayler cardio - facial syndrome based on clinical features and was confirmed with fish analysis.case presentation : a term male baby... |
over the past 3 years , metabolomics has evolved from a little - known branch of analytical chemistry to a main - stream enterprise being practiced by hundreds of laboratories around the world .
thanks to technical advances in nmr spectroscopy , mass spectrometry and compound separation , it is now possible to identi... | the human metabolome database ( hmdb , http://www.hmdb.ca ) is a richly annotated resource that is designed to address the broad needs of biochemists , clinical chemists , physicians , medical geneticists , nutritionists and members of the metabolomics community . since its first release in 2007 ,
the hmdb has been u... |
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