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glycaemia regulation is closely controlled by beta cells ( -cells ) , which routinely monitor blood glucose increases and control insulin release .
blood insulin rise triggers glucose absorption and storage in hepatic , adipose , and muscle cells .
the rapid regulation by -cells permits the blood glucose to return ... | exogenous insulin is the only treatment available for type 1 diabetic patients and is mostly administered by subcutaneous ( sc ) injection in a basal and bolus scheme using insulin pens ( injection ) or pumps ( preimplanted sc catheter ) .
some divergence exists between these two modes of administration , since pumps... |
although endometriosis is recognised as a benign disease , its association with ovarian cancer has been frequently described in the medical literature since 1925 . in that year , sampson established the first histopathological criteria , which are still in use , to identify malignant tumours rising from endometriosis... | introduction .
endometriosis is one of the most common benign disorders which affects 1015% of all women in reproductive age .
the association between endometriosis and ovarian cancer has been frequently described in the medical literature .
purpose . to evaluate the literature for evidence of a correlation betwe... |
acute liver failure ( alf ) , a severe liver damage caused by a variety of factors , is characterized by serious liver dysfunction of synthesis , detoxification , excretion , and biotransformation .
epidemiological data have shown that therapy - associated or suicide - driven overdosage of acetaminophen ( apap ) is t... | human umbilical cord - derived mesenchymal stem cells ( ucmscs ) are particularly attractive cells for cellular and gene therapy in acute liver failure ( alf ) .
however , the efficacy of this cell therapy in animal studies needs to be significantly improved before it can be translated into clinics . in this study , ... |
heterotopic tracheal transplants , placed subcutaneously in syngeneic rats have been extensively used in our laboratory .
the objective of these experiments was to study the toxic and/or carcinogenic effect of several compounds on the respiratory tract mucosa .
this was attained by exposing the transplants to an in... | |
esophageal squamous cell carcinoma ( escc ) is one of the most common and aggressive malignant tumors in china .
although therapeutic strategies have been improved , the prognosis of escc patients is still poor because of the clinicopathological characteristics of escc such as rapid clinical progress , lymph node met... | it has been demonstrated that mtor / p70s6k pathway was abnormally activated in many cancers and rapamycin and its analogs can restrain tumor growth through inhibiting this pathway , but some tumors including esophageal squamous cell carcinoma ( escc ) appear to be insensitive to rapamycin in recent studies . in the pr... |
chemotherapy regimens based on doxorubicin , which is anthracycline antibiotics , are well established in the treatment against a variety of solid malignancies in children . however , the optimal clinical usefulness of doxorubicin is usually limited secondary to the development dose - dependent and irreversible cardiot... | aim : previous studies demonstrated l - carnitine decreasing doxorubicin - induced cardiotoxicity .
our objectives were to study carnitine levels and cardiac functions in children treated with doxorubicin and the effect of short - term l - carnitine supplements.materials and methods : serial carnitine levels and card... |
since platelet activation plays a critical point in the pathogenesis of acs , antiplatelet treatments are frequently used in patients with acute coronary syndrome ( acs ) , in order to reduce ischemic events . the dual antiplatelet therapy that combines aspirin ( acetylsalicylic acid , asa ) and
a platelet p2y12 rece... | background . in acute coronary syndrome ( acs ) , inflammation and redox response are associated with increased residual platelet reactivity ( rpr ) on clopidogrel therapy .
we investigated whether clopidogrel interaction affects platelet function and modulates factors related to inflammation and oxidation in acs pat... |
ganglioneuromas are an intriguing group of neural tumors most commonly located in the posterior mediastinum , retroperitoneum , pelvic and sacral sympathetic ganglia with rare locations in the heart , bone , spermatic cord , middle ear , orbit and skin .
the occurrence of ganglioneuroma in the neck region is limited ... | cervical ganglioneuromas are extremely rare with approximately six case reports .
the current report highlights a unique collision tumor between a cervical ganglioneuroma and a metastatic undifferentiated carcinoma arising from a primary gingival mass . a 53-year - old male presented with a 2 cm left gingival mass th... |
epidemiological and animal studies support a relationship between poor fetal growth and the subsequent development of obesity , type 2 diabetes , and metabolic syndrome [ 14 ] .
such developmental programming has been explained by the thrifty phenotype hypothesis , which proposes that poor fetal nutrition can resul... | we evaluated whether protein restriction in fetal life alters food intake and glucose homeostasis in adulthood by interfering with insulin signal transduction through proinflammatory mechanisms in the hypothalamus and peripheral tissues .
rats were divided into the following : a control group ( c ) ; a recovered grou... |
the ion and water homeostasis , mediated by channels and transporters at the apical and basolateral membranes of secretory epithelia that maintain a fluid compartment at the luminal surface , is essential for the function of different organ systems such as the airways , intestines , and pancreas [ 1 , 2 ] .
the most ... | the pivotal role of epithelial cells is to secrete and absorb ions and water in order to allow the formation of a luminal fluid compartment that is fundamental for the epithelial function as a barrier against environmental factors .
importantly , epithelial cells also take part in the innate immune system . as a firs... |
humidifier disinfectant ( hd ) was used to keep the water in the humidifier water tank sterile from 1995 to 2011 in korea .
but , the aerosolized water droplets became contaminated with chemicals instead . with the evaporation of tiny water droplets , the fine particulates of chemicals entered into the deeper parts o... | according to previous survey , about two million of people were expected to suffer from toxic effects due to humidifier disinfectant ( hd ) , regardless of healing or not .
extremely small group are recognized as hds victims . up to now
, previous research tried to focus on interstitial fibrosis on terminal bronchi... |
this observational study was approved by the institutional ethics committee ( s-057/2009 ) and written informed consent was obtained from all participants .
nine patients with an established diagnosis of l5 radiculopathy or spinal nerve lesion and 3 patients with an established s1 radiculopathy or spinal nerve lesion... | objectives : to investigate whether the human sciatic nerve might have a consistent somatotopic organization according to proximal fascicle input by spinal nerves.methods:twelve patients ( 55.3 15.5 years ) with confirmed lesions of either the l5 or s1 spinal nerve root underwent magnetic resonance neurography of scia... |
hyponatremia is defined as a serum sodium concentration below 135 meq / l ( mmol / l ) and is the most frequently encountered electrolyte abnormality in hospitalized patients .
although it is a common electrolyte disorder , it remains incompletely understood in many basic areas because of its association with a pleth... | background : hyponatremia is one of the most common electrolyte abnormalities encountered in clinical practice and has a significant impact on morbidity and mortality in hospitalized patients
. the optimal management of hyponatremia is still evolving . over the last decade , vaptans have been increasingly used in cli... |
the trigeminal autonomic cephalalgias ( tacs ) are a group of headache disorders characterized by the cardinal combination of short - lasting pain and autonomic phenomena affecting the head .
there is considerable overlap in the features of these entities , with individual defining characteristics predominantly relat... | the trigeminal autonomic cephalalgias ( tacs ) are characterized by the cardinal combination of short - lasting unilateral pain and autonomic phenomena affecting the head , including cluster headache , paroxysmal hemicrania and sunct .
infrequently reported have been cases with dissociation of these two cardinal feat... |
in thyroidectomized patients with differentiated thyroid carcinoma ( dtc ) , it is believed that serum tsh > 30 mu / l optimizes radioiodine trapping and retention and thyroglobulin ( tg ) synthesis by neoplastic cells and is therefore necessary for reliable serum tg testing and efficacious radioiodine therapy [ 14 ] ... | our aim was to test the efficacy of 131-i therapy ( rit ) using recombinant human tsh ( rhtsh ) in patients with differentiated thyroid carcinoma ( dtc ) in whom endogenous tsh stimulation was not an option due to the poor patient 's physical condition or due to the disease progression during l - thyroxin withdrawal . ... |
idiopathic ventricular fibrillation ( vf ) is defined as vf of undetermined etiology in the absence of structural heart disease and it accounts for 5 - 10% of survivors of out - of - hospital sudden cardiac arrest.1 )
recurrent idiopathic vf triggered by unifocal premature ventricular complexes ( pvcs ) can be manage... | a 17-year - old man was referred for aborted sudden cardiac death .
ventricular fibrillation ( vf ) was recorded by automated external defibrillator .
post - resuscitation electrocardiograms showed frequent monomorphic premature ventricular complexes ( pvcs ) , with left bundle branch block configuration and inferi... |
over the past two decades , microarray technologies have been used to characterize gene expression in various contexts , notably complex human disease and corresponding animal models .
many , perhaps most , analyses could be enriched by comparison with other experiments across species and platforms .
however , expe... | pathway analysis is important in interpreting the functional implications of high - throughput experimental results , but robust comparison across platforms and species is problematic .
a new approach , pathprinting , provides a cross - platform , cross - species comparative analysis of pathway expression signatures ... |
the fbi is reading our poster ! granted , this is not a typical refrain heard at the annual meetings of the american society for cell biology , but it is heard frequently at other research meetings , for example , in the field of synthetic biology .
i admit that it was head turning when i first heard these words spo... | new scientific frontiers and emerging technologies within the life sciences pose many global challenges to society .
big data is a premier example , especially with respect to individual , national , and international security . here
a special agent of the federal bureau of investigation discusses the security impl... |
in the previous issue of critical care , ma and colleagues report a meta - analysis of the randomized , clinical trials of clazosentan and tak-044 in patients with aneurysmal subarachnoid hemorrhage ( sah ) . the endothelins ( ets ) are a family of three ( et-1 , et-2 and et-3 ) 21-amino - acid peptides that act on sev... | in the previous issue of critical care , ma and colleagues perform a meta - analysis of five randomized , clinical trials of endothelin antagonists in patients with aneurysmal subarachnoid hemorrhage .
there are four trials using clazosentan and one trial with tak-044 .
these studies show that endothelin plays an i... |
cross - presentation is the process by which extracellular antigens , which are normally presented in association with mhc class ii molecules , are instead presented by mhc class i molecules .
this differs from the classical mhc class i processing pathway in which mhc class i molecules present antigens that are synth... | cross - presentation of extracellular antigens by mhc class i molecules is required for priming cytotoxic t lymphocytes ( ctls ) at locations remote from the site of infection .
various mechanisms have been proposed to explain cross - presentation .
one such mechanism involves the fusion of the endoplasmic reticulu... |
congenital syphilis is acquired by an infant from an infected mother by transplacental transmission of treponema pallidum during pregnancy or possibly at birth from contact with maternal lesions . in the recent years , due to improved medical care , congenital syphilis has become a comparative rarity .
we are reporti... | congenital syphilis is a severe , disabling infection that occurs due to the transmission of treponema pallidum across the placenta during pregnancy or from contact with an infectious genital lesion during delivery .
however , its early diagnosis is often difficult because more than half of the affected infants are a... |
receptor occupancy at doses commonly used in the polypharmacy treatment of schizophrenia frequently surpasses the dose needed for effective therapy . despite an increased risk of side effects ( farde et al . , 1992 ) ,
therapy with a combination of agents remains a part of the general practice ( barnes and paton , 20... | background : polypharmacy for schizophrenia treatment is not justified by the available clinical evidence .
we evaluated a treatment reduction approach that reduces the dose and number of antipsychotic medications simultaneously prescribed to patients.methods:in a randomized open study of the safe correction of antip... |
lanthanum carbonate ( lc ) is a non - calcium , non - aluminum phosphate binder used to treat hyperphosphatemia in end - stage renal disease .
there , this cation binds with phosphate to produce lanthanum phosphate , which is excreted with the feces .
it has been reported that lanthanum is absorbed and deposited in... | lanthanum carbonate ( lc ) is an orally administered phosphate binder .
its absorption is generally thought to be minimal .
we report here the case of an 81-year - old woman who underwent subtotal gastrectomy for gastric cancer after receiving hemodialysis for 1 year and taking lc for 7 months .
lanthanum phospha... |
preoperative co - morbidities , long duration of surgery , large fluid shifts , and delayed correction of metabolic derangements by the transplanted liver are the common factors responsible for preventing primary extubation after liver transplantation . moreover , until very recently , a postoperative period of mechani... | liver transplantation is a dynamic field undergoing continuous changes in management .
prolonged postoperative mechanical ventilation has been a norm but now there is a trend towards early extubation .
we developed a protocol for early extubation based on bispectral index monitoring .
this protocol was applied in... |
beside endothelial dysfunction leading to inflammatory reaction , lipid metabolism disorders represent the second key event in the initiation and rapid development of atherogenesis . many individual lipid and inflammatory markers
have been considered as the factors playing an important role in atherogenesis and pro... | this study evaluated whether statin therapy changed a diagnostic validity of lipid and inflammatory markers in ischemic heart disease ( ihd ) patients .
levels of lipids , lipoproteins , apolipoproteins , inflammatory markers , and atherogenic indexes were determined in 49 apparently healthy men and women , 82 patien... |
radiation
therapy ( rt ) is one of the most accepted and widely used
treatments for primary and metastatic intracranial tumors .
recent
technical advances in rt and multimodality approaches to treatment
have increased the life span of many patients ; however , a major concern
remains as to radiation s effec... | whole brain radiotherapy ( wbrt ) produces
unwanted sequelae , albeit
via unknown mechanisms .
a deacetylase expressed in the central nervous
system , sirtuin 2 ( sirt2 ) , has been linked to neurodegeneration . therefore ,
we sought to challenge the notion that a single disease pathway is
responsible for r... |
replication protein
a ( rpa ) is a single stranded dna ( ssdna)binding
protein complex that is essential for dna replication , damage response ,
and repair . in response to dna lesion formation ,
rpa
rapidly coats ssdna , preventing the formation of aberrant
dna structures at replication foci and recruiting... | stapled helix peptides can serve
as useful tools for inhibiting
protein protein interactions but can be difficult to optimize
for affinity . here
we describe the discovery and optimization of a
stapled helix peptide that binds to the n - terminal domain of the 70
kda subunit of replication protein a ( rpa7... |
in the discussion that follows , it is crucial to distinguish three closely related concepts .
this distinction was proposed in the i m protocol , which also provides useful definitions ( bartholomew et al . , 1998 , 2011):methods of behaviour change : theoretical processes of change according to psychological theory... | there is a need to consolidate the evidence base underlying our toolbox of methods of behaviour change .
recent efforts to this effect have conducted meta - regressions on evaluations of behaviour change interventions , deriving each method 's effectiveness from its association to intervention effect size . however ,... |
this case study was performed with the cooperation of the san diego police department and was necessarily relatively limited in scope .
however , we felt the results of the case study needed to be published as the officers ' feedback was surprisingly strong and positive , and we did achieve statistically significant ... | weltman et al have presented a fascinating report on the effectiveness of a stress resilience training program on police department personnel ( global adv health med . 2014;3(2):72 - 79 ) .
certainly at first reading there appears to be strong evidence of the effectiveness of the program .
however , careful evaluat... |
the levonorgestrel intrauterine system ( lng - ius ) , originally developed for long - term contraceptive use , has shown to have a profound effect on the endometrium .
the system has been used extensively for the treatment of heavy menstrual bleeding and for the conservative treatment of non - atypical as well as at... | prevention of progression to invasive carcinoma in patients with a premalignant endometrial lesion using longterm treatment with levonorgestrel ( lng ) releasing intrauterine systems ( ius ) remains controversial , especially when manifest cellular atypia has been found in the endometrial biopsy specimen .
we present... |
three - month - old skeletally mature male new zealand white rabbits ( n = 54 , 3.5 0.5 kg ; jung - ang animal laboratory , seoul , korea ) were housed in cages and fed commercially available rabbit food .
nih guidelines for the care and use of laboratory animals published by the national institute of health ( nih p... | backgroundto determine if exogenously injected bone marrow derived platelet - rich plasma ( prp ) plus bone morphogenetic protein ( bmp)-2 could accelerate the healing of bone - tendon junction injuries and increase the junction holding strength during the early regeneration period.methodsa direct injury model of the b... |
type 2 diabetes mellitus ( t2 dm ) is characterized by hyperglycemia related to a progressive loss of beta cell function
. the selection of initial antihyperglycemic therapy influences treatment failure and the need for additional therapy in individuals with t2 dm . metformin and sulfonylureas are the two most common... | backgroundin type 2 diabetes mellitus ( t2 dm ) , progressive loss of beta cell function over time requires treatment intensification and eventually initiation of insulin for many patients .
relative to metformin , a greater rate of decline in beta cell function over time has been observed with sulfonylurea treatment... |
in the united states , men who have sex with men ( msm ) exhibit disproportionately high incidence and prevalence of hiv infection .
msm represent an estimated 4.79.2% of the total united states ( us ) population yet , in 2009 , accounted for 61% of all new hiv infections in the us .
risk factors for hiv infectio... | methamphetamine use among men who have sex with men ( msm ) is associated with increased hiv prevalence , due to increased engagement in high - risk sexual behavior .
fifty - three hiv - negative , methamphetamine - using msm were enrolled in a biobehavioral combination prevention intervention in los angeles , ca , t... |
although lumbar disc extrusions are frequently observed in neurosurgical practice , posterior epidural migration of an extruded prolapsed intervertebral disc fragment is rare4,6 ) . the migration of disc fragments is generally contained in the anterior epidural space , which is well defined and delineated by the poster... | dorsal extradural migration of extruded disc material is clinically uncommon . we report a rare case of posterior epidural migration of an extruded lumbar disc mimicking a facet cyst .
a 32-year - old man was admitted to our institute with a 2-week history of severe low back pain and radiating pain in the left leg . ... |
to preserve the homeostasis and health of the organism cells are constantly responding to changes in the physical and chemical properties of the environment by altering many of their cellular functions .
the activation of mitogen activated protein kinases ( mapks ) is involved in the transduction of most extracellula... | the mammalian p38 mitogen - activated protein kinases ( mapks ) family is composed of four members ( p38 , p38 , p38 , and p38 ) , which are very similar in amino acid sequence but differ in their expression patterns .
this suggests that they may have specific functions in different organs . in the last years
most ... |
we conducted a cross - sectional epidemiologic and serologic survey to determine the prevalence of igg antibodies against hantavirus n antigen in the adults living in nine communities of the ix region of chile .
the ix region of chile is located in the southern part of the country , between parallel 37 and 40 south a... | an epidemiologic and seroprevalence survey was conducted ( n=830 ) to assess proportion of persons exposed to hantavirus in ix region chile , which accounts for 25% of reported cases of hantavirus cardiopulmonary syndrome .
this region has three geographic areas with different disease incidences and a high proportion... |
hand x - ray shown in figure 1 is commonly used for skeletal age assessment in pediatric radiology . a discrepancy between skeletal maturity and the chronical age
this abnormality has been found to be related to various diseases such as endocrine disorders , metabolic / growth abnormalities , malformations and bone d... | accurate assessment of skeletal maturity is important clinically .
skeletal age assessment is usually based on features encoded in ossification centers .
therefore , it is critical to design a mechanism to capture as much as possible characteristics of features .
we have observed that given a feature , there exis... |
gastric cancer is the most common malignancy in korea . in recent years , mortalities associated with gastric cancer have decreased markedly in some asian countries due to healthcare policies that introduced screening tests for early detection of gastric cancer . since curative treatment is possible when tumors are res... | endoscopic mucosal resection was introduced in the 1990s , and endoscopic submucosal dissection ( esd ) in 2003 .
currently , esd is becoming the main procedure for the resection of early gastric cancer ( egc ) and is leading to the development of extended indications for endoscopic resection .
many reports showed ... |
sulfur dioxide ( so2 ) may act as a cocarcinogen with benzo[a]pyrene ( bap ) in the respiratory tract .
we have modeled this effect by examining the interactions of 7r,8t - dihydroxy-9t,10t - epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene ( anti - bpde ) with sulfite , the physiological form of so2 , in a murine respiratory... | |
during coevolution of mammalian organisms and retroelements , the hosts have developed defense systems to restrict replication of these elements .
the restriction factors include the a3 family of dna cytidine deaminases , which is characterized by the presence of one or two zn clusters consisting of ( h / c)xe(x)2328... | human apobec3 ( a3 ) proteins are cellular cytidine deaminases that potently restrict the replication of retroviruses by hypermutating viral cdna and/or inhibiting reverse transcription .
there are seven members of this family including a3a , b , c , de , f , g , and h , all encoded in a tandem array on human chromos... |
photodynamic therapy ( pdt ) is a potential model for cancer therapy , which has been used to treat or relieve the symptoms of skin cancer , esophageal cancer , prostate cancer , and non - small cell lung cancer [ 13 ] . during the pdt procedure , the excited photosensitizer forms highly reactive oxygen species using v... | photocyanine is a novel anticancer drug .
its pharmacokinetic study in cancer patients is therefore very important for choosing doses , and dosing intervals in clinical application .
a rapid , selective and sensitive high - performance liquid chromatography - tandem mass spectrometry ( hplc - ms / ms ) method was d... |
it is accompanied by valgus deformity and external rotation at knee in long standing cases secondary to the contracture of the iliotibial tract .
flexion deformity at knees is an impediment to the normal ambulation and is difficult to address .
he had multifocal tuberculosis and was bed ridden for almost a year and... | introduction : bilateral flexion deformity commonly results secondary to cerebral palsy , poliomyelitis , haemophilia etc .
it is accompanied by valgus deformity and external rotation at knee in long standing cases secondary to the contracture of the iliotibial tract .
flexion deformity at knees is an impediment to... |
women aged 20 to 45 years with regular menstrual cycles and experience of pms symptoms ( according to the current diagnostic criteria proposed by the american college of obstetrics and gynecology ) ( 4 ) for at least 6 months were eligible for the study .
the exclusion criteria were as follows : pregnancy or lactatio... | objectivepremenstrual syndromes ( pms ) affecting 2040% of women of reproductive age .
the aim of this double blind and placebo controlled trial was to investigate whether femicofort a supplement contains vitamin b6 , vitamin e and evening primrose oil could relieve symptoms of pms.methodthis was a randomized and dou... |
urine is composed of numerous harmful metabolites , which are stored for prolonged time in the urinary bladder.1 for that , the primary function of urinary bladder is to prevent internalization of metabolites from bladder lumen into the underlying tissues and blood.2 this blood - urine permeability barrier has to remai... | backgroundurothelial bladder is the reservoir of urine and the urothelium minimizes the exchange of urine constituents with this tissue .
our aim was to test 1.9 nm biocompatible gold nanoparticles as a novel marker of internalization into the urothelial cells under physiological conditions in vivo.methodswe compared... |
one of the main reasons for assessing a patient prior to orthodontic treatment is to determine the number of teeth present .
the developmental absence of one or more teeth from the dentition is known as hypodontia.1 clinicians often claim that hypodontia has increased during recent decades
. possible explanations f... | objectivethe aim of this study was to document the prevalence of hypodontia in the permanent dentition among a group of turkish sample who sought orthodontic treatment and to compare present results with the specific findings of other populations .
the occurrence was evaluated in relation to gender , specific missing... |
vegf appears to be one of the major regulators in cnv among the angiogenic factors studied so far ; vegf plays a central role in the development of cnv .
the vegf family includes placenta growth factor , vegf - a , vegf - b , vegf - c , vegf - d and vegf - e .
briefly , vegf - a plays a pivotal role in the developm... | recent developments may provide an opportunity to improve outcome in individuals who develop neovascular age - related macular degeneration ( armd ) .
several therapies have been introduced that show promise for halting the progression of this disorder .
however , data from controlled clinical trials to test the re... |
given the nature of emergency medical services ( ems ) work , it is not surprising that musculoskeletal injuries are the leading cause of reported morbidity .
wrist pain in rescuers performing chest compressions as part of cardiopulmonary resuscitation has been reported anecdotally and recently in the literature .
... | wrist pain in rescuers performing chest compressions as part of cardiopulmonary resuscitation has been reported anecdotally and recently in the literature .
studies have indicated that rescuers apply as much as 644 n of force to the victim 's chest with each compression , while standards require one hundred compressi... |
abdominal pregnancy is a rare type of ectopic pegnancy with an estimated incidence being 1 in 8,000 births and 1.4 % of all ectopic pregnancies .
most commonly , the site of implantation in an abdominal pregnancy is pelvic , but very rarely it may implant in the upper abdomen .
the authors report such a case of pri... | a 25-year - old g2p1l1 woman with 18-week pregnancy presented with right hypochondriac pain and vomiting for the past 1 week .
she had borderline vitals and a diffusely tender abdomen .
ultrasound revealed a live 18-week fetus attached to the undersurface of the liver with moderate ascites .
laparotomy was carrie... |
anti - n - methyl - d - aspartate ( anti - nmda ) receptor encephalitis is an acute , immune - mediated paraneoplastic syndrome with a characteristic sequential clinical course .
it includes a prodrome of flu - like illness progressing to behavior changes , psychosis , and memory deficit .
dyskinesia , seizure atta... | anti - n - methyl - d - aspartate ( anti - nmda ) receptor encephalitis is a newly recognized , potentially fatal , but treatable autoimmune disease .
good outcome predictors include milder severity of symptoms , no need for intensive care unit admission , early aggressive immunotherapy , and prompt tumor removal .
... |
pancreatic adenocarcinoma is the fourth leading cause of the cancer deaths in the united states . in 2012
, it was estimated that over 43,900 patients developed pancreatic cancer and almost 37,390 died from this disease .
endoscopic ultrasound - guided fine - needle aspiration ( eus - fna ) is recognized as a safe ... | background and objectives : recent reports have indicated that the time of day may impact the detection rate of abnormal cytology on gynecologic cytology samples .
the aim of this study was to determine if procedure time or queue position affected the performance characteristics of endoscopic ultrasound - guided fine... |
the positron emission tomography ( pet ) tracer 3-deoxy-3-[f]fluorothymidine ( [ f]flt ) , a thymidine analogue that is a marker of tumour proliferation , is a promising tracer for monitoring treatment response and predicting outcome .
it has been shown that [ f]flt uptake strongly correlates with the proliferation i... | purposepositron emission tomography using 3-deoxy-3-[18f]fluorothymidine ( [ 18f]flt ) has been suggested as a means for monitoring response to chemotherapy .
the aim of this study was to evaluate the validity of simplified uptake measures for assessing response to chemotherapy using [ 18f]flt in locally advanced bre... |
polycystic ovary syndrome ( pcos ) is the most complex and common endocrine disorder affecting women in their reproductive years and is characterized by irregular menstrual cycles , chronic anovulation and hyperandrogenism .
the specific population based studies in india shows a 3 - 10% prevalence of this disorder in... | background : polycystic ovary syndrome ( pcos ) is the most complex and common endocrine disorder of women in reproductive years .
in addition to irregular menstrual cycles , chronic anovulation and hyperandrogenism , it has many metabolic manifestations such as obesity , hyperlipidemia , hyperinsulinemia , insulin r... |
arthroscopic debridement and bone marrow stimulation is considered the primary treatment of osteochondral talar defect ( ocd ) and yields 85% success . in case of failure of the primary treatment ,
current secondary treatment options include repeat arthroscopic debridement and bone marrow stimulation , osteochondral ... | the primary treatment of most osteochondral defects of the talus is arthroscopic debridement and bone marrow stimulation .
there is no optimal treatment for large lesions or for those in which primary treatment has failed .
we report a 20-year - old female patient with persistent symptoms after two previous arthros... |
submucous fibroids arise beneath the endometrial layer and often project into endometrial cavity , interstitial or intramural fibroids arise within the myometrium , and subserous fibroids arise from serosal layer and present as adnexal masses .
extra - uterine fibroids may develop in the broad ligament or at other si... | giant fibroids are known to arise from the uterus , and very rarely from the broad ligament .
large fibroids often undergo hyaline , cystic , and at times , red degeneration . in the present case ,
cystic degeneration with intervening septations in an adnexal mass raised the suspicion of ovarian neoplasm as the ova... |
omics can inform you
if the steak you are about to enjoy will be
tender and juicy or if your glass of wine will be sweet or dry before
your first sip and can provide you a genetic map to growing the deepest - red
tomato possible .
the panomic arsenal of omic tools is enhancing the
quality , taste , and nutr... | the agrochemicals division cosponsored
the 13th international union
of pure and applied chemistry international congress of pesticide
chemistry held as part of the 248th national meeting and exposition
of the american chemical society in san francisco , ca , usa , august
1014 , 2014 . the topic of the congres... |
this article reviews exposure information available for trichloroethylene ( tce ) and assesses the magnitude of human exposure .
the primary sources releasing tce into the environment are metal cleaning and degreasing operations .
releases occur into all media but mostly into the air due to its volatility .
it is... | |
temporal lobe of epilepsy ( tle ) is known to be the most common form of partial epilepsy and accounts for 60% of seizures .
depending on the seizure origin , tle should be subdivided into mesial , lateral , and neocortical .
partial epilepsies are often associated with antecedent of brain injury , such as head tra... | temporal lobe epilepsy ( tle ) is usually regarded as a polygenic and complex disorder . to understand its genetic component ,
numerous linkage analyses of familial forms and association studies of cases versus controls have been conducted since the middle of the nineties .
the present paper lists genetic findings ... |
typically , retropharyngeal hematomas have been reported to be related with anticoagulant therapy , iatrogenic injury , infections , foreign body ingestion , and vascular lesions145614161820 ) .
although major trauma , such as cervical spinal fracture , has caused retropharyngeal hematomas61017 ) , minor trauma is ra... | only a few cases of anterior longitudinal ligament ( all ) injury related with retropharyngeal hematoma without fracture have previously been reported . the treatment of choice for retropharyngeal hematoma is generally considered to be conservative care , but we believe that early surgery of this pathology would be bet... |
evidence has accumulated in recent years to indicate that early life adversaries have a profound impact on the developing brain structure and functions , long after the original traumatic experience has vanished .
one of the extensively studied structures in the brain in relation to early life stress has been the hip... | early life adversaries have a profound impact on the developing brain structure and functions that persist long after the original traumatic experience has vanished .
one of the extensively studied brain structures in relation to early life stress has been the hippocampus because of its unique association with cognit... |
rice contains 10 times more arsenic
than other cereal staples and is the dominant
food source of inorganic
arsenic exposure to the world s population .
the
prevalence of lead - enriched rice is less than that of arsenic but
is a particular concern in regions where waste recycling and base
metal mining coe... | in
wetland - adapted plants , such as rice , it is typically root apexes ,
sites of rapid entry for water / nutrients , where radial oxygen losses
( rols ) are highest .
nutrient / toxic metal uptake therefore largely
occurs through oxidized zones and ph microgradients .
however , the
processes controllin... |
blood group phenotypes have been used for several applications as for blood transfusion practices and population genetic studies [ 13 ] . in morocco
, no study has identified yet the distribution and frequency of different blood groups . in this perspective
we tried to identify the rhesus phenotypes in nine differe... | the aim of this research is to search for the distribution of blood groups in all the regions of morocco .
this study , done for the first time , aimed to provide the frequency of the rhesus system and kell ( k ) in more than 55000 blood donors from nine different regions around the country .
in addition , the freq... |
calcifying psuedoneoplasm(cpn ) involving the neural axis is very rare , with spinal involvement being even less frequent .
about 20 cases of spinal cpn have been reported since the first description in 197816 ) .
the symptoms of spinal cpn vary from asymptomatic lesion to isolated pain , radiculopathy , or myelopa... | calcifying psuedoneoplasm of the spine is a rare non - neoplastic lesion of unknown origin .
radiologic and histologic manifestations are very variable and clinical symptoms include isolated pain , myelopathy , and radiculopathy .
surgical resection is the preferred option of treatment .
this report describes thr... |
plaque rupture or endothelial erosion with subsequent occlusive thrombus formation is the primary cause of acute coronary syndrome ( acs)- .
it has been generally accepted that plaque vulnerability is an underlying mechanism for this local phenomenon . however
, plaque instability may reflect a pan - vascular proce... | abstractwe report a case of a 49-year - old man who was admitted with a 3-hour history of sudden onset of substernal chest pain .
coronary angiography revealed that the left circumflex artery ( lcx ) was acutely and totally occluded at the mid - portion .
in addition , the proximal and mid - portion of the right co... |
from van leeuwenhoek s description of his animacules soon after the development of the microscope , cell biology has always been linked with single - celled organisms .
nonetheless , studies of cell biology and physiology remain restricted to relatively few model organisms , such as flies , worms , yeasts , and hum... | in animal and fungal model organisms , the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level .
however , the model organisms cell biologists generally use include only a tiny fraction of the true diversity of eukaryotic cellu... |
platinum analogs have been the standard of care in management of advanced stage epithelial ovarian and fallopian tube carcinoma .
platinum and taxane combination has shown a survival benefit in the firstline as well as in relapse setting .
carboplatin being equally efficacious and with better toxicity profile has r... | carboplatin and paclitaxel as doublet are the standard therapeutic option for advanced stage ovarian carcinoma in the first line as well as relapse . carboplatin with its better toxicity profile has replaced cisplatin as the first line drug .
however , increase in incidence of carboplatin hypersensitivity is alarming... |
idiopathic chronic pancreatitis associated with minimal clinical symptoms , icterus and notable hypergammaglobulinaemia was first described in 1961 by sarles et al.1 in 1995 , yoshida et al.2 documented a case of a 68-year - old woman with obstructive icterus , diffusely enlarged pancreas with irregular caliber of panc... | autoimmune pancreatitis ( aip ) type 1 is commonly associated with simultaneous involvement of extrapancreatic organs .
sclerosing cholangitis , sialadenitis , retroperitoneal fibrosis , sjgren syndrome , and other extrapancreatic lesions are often observed concurrently with aip .
high levels of immunoglobulin g4 (... |
chronic meningitis , defined by at least 1 month of unresolved inflammation of the cerebrospinal fluid ( csf ) , is a difficult illness to diagnose and treat . regardless of cause ,
presenting symptoms can include headache , nausea / vomiting , cranial neuropathies , or other focal neurological deficits . after a com... | we report the case of a 63-year - old male diagnosed with chronic autoimmune mediated meningoencephalitis and periodic cyclical fever syndrome .
after 2 years of failed conventional treatment and recurrent hospitalizations , anakinra treatment ( an interleukin-1 [ il-1 ] receptor antagonist ) was trialed which result... |
since the original description of the disease by alois alzheimer , memory difficulties are considered the initial and the most prominent and typical symptom of alzheimer 's disease .
more recently , the detection of elderly subjects with mild cognitive impairment and a high risk of progression to alzheimer 's disease... | diagnosis of mild cognitive impairment relies on the presence of memory complaints . however , memory complaints are very frequent in healthy people . the objective of this study was to determine the severity and type of memory difficulties presented by elderly patients who seek for clinical help , as compared to the m... |
around one of every ten patients presenting with a sudden severe headache in general practice has a subarachnoid haemorrhage ( sah ) .
computed tomography ( ct ) scanning of the brain can confirm the diagnosis in most but not all instances .
in particular , in patients who present late , ct can be non - diagnostic ... | in patients with sudden severe headache and a negative computed tomography ( ct ) scan , a lumbar puncture ( lp ) is performed to rule in or out a subarachnoid haemorrhage ( sah ) , but this procedure is under debate . in a hospital - based series of 30 patients with sudden headache , a negative ct scan but a positive ... |
type 2 diabetes ( t2 dm ) is a complex disease characterized by chronic hyperglycemia .
beta cell dysfunction and insulin resistance are the main pathogenetic factors associated with t2 dm . the evolution of t2 dm is characterized by a progressive decline of -cell function that leads to the failure of oral antidiabet... | objectives . the mechanism underlying the regulation of glucolipotoxicity - induced apoptosis by mapks was examined in ins-1 cells .
methods .
the rat insulinoma cell line ins-1 was cotreated with glucose ( 30 mm ) and palmitic acid ( 0.2 mm ) ( glu+pa ) .
apoptosis was assessed by cell morphology and detection... |
published literature on integrated care usefully brings together wide - ranging definitions and concepts ( e.g. , breadth , function ) but pays little attention to the historical record ( e.g. , political priorities , policy agendas , and social pressures ) .
to draw out lessons for future policy by considering uk po... | introductionpublished literature on integrated care usefully brings together wide - ranging definitions and concepts ( e.g. , breadth , function ) but pays little attention to the historical record ( e.g. , political priorities , policy agendas , and social pressures ) .
historical analysis highlights how these facto... |
hydatid cyst disease is one of the most important zoonotic diseases , which occur , in larval stage of echinococcus granulosus parasite . in this disease ,
canines such as dog , wolf , fox , and jackal ( the final host ) are infected by eating contaminated viscera , and small adult worms with size of 27 mm are formed... | background : this study aimed to investigate the epidemiological and clinical aspects of patients with hydatid cyst during 2011 to 2014.methods:this cross - sectional study was conducted in khorasan razavi province , the northeast of iran , from 2011 to 2014 .
the study population was all cases with hydatid cyst who ... |
this investigation is based on the esther study , an ongoing cohort study including 9,949 subjects , 5074 years of age at baseline .
study participants were recruited by their general practitioners during a routine health check - up between 2000 and 2002 in saarland , a federal state of germany ( 1214 ) .
the distr... | objectiveinflammatory processes contribute to both diabetes and cardiovascular risk .
we wanted to investigate whether circulating concentrations of proinflammatory immune mediators and adiponectin in diabetic patients are associated with incident cardiovascular events.research design and methodsin 1,038 participants... |
the family of g - protein coupled receptors ( gpcrs ) represents one of the most important classes of pharmaceutical targets ( 1 ) . among the more than 1000 gpcrs encoded in the human genome ,
currently the drugs available on the market address only 30 gpcrs , which represent a small fraction of the gpcr target fami... | g - protein coupled receptors ( gpcrs ) represent one of the most important families of drug targets in pharmaceutical development .
glida is a public gpcr - related chemical genomics database that is primarily focused on the integration of information between gpcrs and their ligands .
it provides interaction data ... |
free radicals ( i.e. , molecules with one
or more unpaired electrons )
are ubiquitous in living systems as well
as engineered synthetic routes .
the number
of stable radicals is comparatively small , because of the peculiar requirements for stabilizing the unpaired
electron state against reaction with its a... | stable hydrocarbon radicals are able to withstand ambient
conditions .
their combination with a supporting surface is a promising route toward
novel functionalities or carbon - based magnetic systems .
this will
remain elusive until the interplay of radical radical interactions
and interface effects is fun... |
denture stomatitis ( ds ) is defined as an inflammatory process of the oral mucosa underlying a removable , partial or total , dental prosthesis.1 etiological factors in ds include the trauma caused by an ill - fitting denture , lack of oral and prosthesis hygiene and a favorable environment for the proliferation of mi... | background : effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis ( ds ) .
this study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating c. albicans colonizing dentures.materials and methods : a total of 40 denture wearers ( 18 men , ... |
gingival recession is a matter of concern for both patients and dental professionals , especially when exposure of the root surface is linked to deterioration in esthetic appearance and increase in dental hypersensitivity .
the presence of gingival recession exemplifies a situation in which a treatment modality that ... | dentinal hypersensitivity and unesthetic appearance are common findings after excision of an epulis due to exposure of root and underlying bone .
the simultaneous placement of subepithelial connective tissue grafting after excision of the lesion seems to be viable surgical option in such cases .
furthermore , this ... |
a sequence of nh2-aaaagaaacp - cooh was used as the switch - tag ( st ) ( munoz and serrano 1994 ) . we have previously observed that c - terminal cysteines , which have thiol and carboxylic acid groups in close proximity , can be self - proteolytic and thus added a protecting c - terminal proline residue which does no... | surface biology aims to observe and control biological processes by combining bio- , surface , and physical chemistry .
self - assembled monolayers ( sam ) on gold surfaces have provided excellent methods for nanoscale surface preparation for such studies . however ,
extension of this work requires the specific imm... |
the study was conducted in a primary care clinic serving low - income patients in central honduras .
eight hundred adult patients , who were not pregnant , did not have a heart attack in the prior 3 months , and had no diagnosis of diabetes were recruited .
participants completed a face - to - face interview and a ... | objectiveto validate a low - cost tool for identifying diabetic patients in rural areas of latin america.research design and methodsa regression equation incorporating postprandial time and a random plasma glucose was used to screen 800 adults in honduras .
patients with a probability of diabetes of 20% were asked to... |
although diabetes is highly prevalent worldwide , its presence among american indians and alaska natives ( ai / ans ) is particularly alarming . adjusting for age ,
ai / ans suffer from type 2 diabetes mellitus at rates greater than two times those of non - hispanic whites and exhibit the highest prevalence of this d... | the association of psychosocial factors ( psychological distress , coping skills , family support , trauma exposure , and spirituality ) with initial weight and weight loss among american indians and alaska natives ( ai / ans ) in a diabetes prevention translational project was investigated .
participants ( n = 3,135... |
the effectiveness of a stent lies in its capability to resist elastic outward recoil of the artery in which it has been implanted : a major indicator of such feature is the stent radial force ( rf ) ( ref 1 ) , which the manufacturers need to quantify according to international standards ( ref 2 , 3 ) in order to obtai... | the present article presents a method for assessing the radial stiffness of nitinol stents .
an idealized stent model was created , and its radial stiffness was calculated by means of finite element modeling .
the calculations were validated against experimental measurements .
the variation of radial stiffness wi... |
bock et al . described 23 chronically hypokalaemic patients , 21 women , that they followed up for > 6 years ( not quite ) 40 years ago .
the causes of hypokalaemia were malnutrition , laxative abuse , self - administered diuretic usage or a combination of these factors .
gradually over time , renal function dete... | in the older literature , a definitive renal pathology was described in patients with long - standing hypokalaemia and depletion of the body 's potassium reserves .
the topic is relevant because possibly a quite cheaply reversible element in the course of chronic kidney disease progression could be addressed .
ear... |
atrial fibrillation ( af ) is the most commonly encountered clinical cardiac arrhythmia , and recent data suggests the prevalence of this disease in western societies is 1%-3% of adults over the age of 20 .
, individuals with af are at increased risk of cardiovascular and cerebrovascular morbidity and mortality compa... | atrial fibrillation ( af ) is the most commonly encountered cardiac arrhythmia , and is a significant source of healthcare expenditures throughout the world .
it is an arrhythmia with a very clearly defined predisposition for individuals of advanced age , and this fact has led to intense study of the mechanistic link... |
besides controlling gene transcription and growth , ca regulates the contraction and relaxation in muscles tissue . skeletal and cardiac muscle
ca cycling in muscle tissue is regulated by a plethora of proteins , transmitting the ca messages with precision and in a temporally and spatially coordinated manner .
one ... | calcium ( ca2 + ) signaling plays a key role in a wide range of physiological functions including control of cardiac and skeletal muscle performance . to assure a precise coordination of both temporally and spatially transduction of intracellular ca2 + oscillations to downstream signaling networks and target operations... |
the fine adjustment of intracellular iron levels is mainly achieved by means of a divergent
but coordinated regulation of the iron - storage protein ferritin and the iron - uptake protein
tfr1 . although transcriptional regulation of the ferritin heavy and light subunits
( h - ferritin and... | iron is required for key cellular functions , and there is a strong link between iron
metabolism and important metabolic processes , such as cell growth , apoptosis and
inflammation .
diseases that are directly or indirectly related to iron metabolism
represent major health problem... |
stochastic sensors based on nanopores
are under intense investigation . in this approach to single - molecule detection , the reversible interaction
of an analyte with a pore alters the current flowing through it , which
is carried by aqueous ions .
the change in the current amplitude and
the mean dwell time ... | protein nanopores have been used as stochastic sensors
for the
detection of analytes that range from small molecules to proteins .
in this approach ,
individual analyte molecules modulate the ionic
current flowing through a single nanopore . here , a new type of stochastic
sensor based on an hl pore modifie... |
cysticercosis , caused by the tapeworm taenia solium , is the most common parasitic disease affecting the central nervous system1 ) .
cysticercosis typically infiltrates the brain parenchyme , while spine infection of neurocysticercosis is rare with incidence of 1 - 3%1,2,15 ) .
in addition , the neurocysticercosis... | cysticercosis is the most common parasitic disease affecting the central nervous system .
spinal involvement is rare in neurocysticercosis , and isolated spinal involvement without evidence of cranial involvement is even rarer .
we report an unusual case of neurocysticercosis with isolated spinal involvement . a 59... |
compared to similarly aged nondiabetic adults , persons with type 1 diabetes ( t1d ) are more likely to exhibit cognitive deficits , especially localized within the psychomotor and information processing domains [ 15 ] .
slower psychomotor speed is associated with several negative health outcomes , in persons both wi... | slower psychomotor speed is very common in patients with type 1 diabetes mellitus ( t1d ) , but the underlying mechanisms are not clear . we propose that hyperglycemia is associated with slower psychomotor speed via disruption of brain activation .
eighty - five adults ( 48% women , mean age : 49.0 years , mean durat... |
experimental animals : a total of 4 male wistar rats aged 7 weeks ( japan
slc inc . ,
the animals were maintained under conventional
laboratory housing conditions and permitted free access to water and food ( lab mr stock ;
nosan corp . ,
the animal facility was maintained under conditions of a
12-hr light ... | abstractchylomicrons from villous columnar epithelial cells are generally known to be
transported only by central lymph vessels ( clv ) , whereas antigenic particulates derived
from the intestinal lumen can also be transported by subepithelial blood capillaries
( sbcs ) in rat intestinal villi .
the possibility... |
posttransplant lymphoproliferative disorder ( ptld ) is one of the most serious complications after solid organ transplantation and hematopoietic stem cell transplantation ( hsct ) .
the incidence has been reported to be about 1 percent of all transplantations ( 1 , 2 ) .
ptlds , including polyclonal lymphoprolifer... | a 16-yr - old girl received liver transplantation for fulminant hepatitis .
aplastic anemia developed , and she received hematopoietic stem cell transplantation ( hsct ) .
eleven months after liver transplantation , abdominal lymph node enlargement and colon ulcers were observed , and colon biopsy showed posttransp... |
cytotoxic t lymphocytes , nk cells , dcs and macrophages play important roles in immune responses against foreign antigens , pamps and damps ( 1 ) .
previous investigations evidenced that chemokines serve as recruiters of the above - mentioned parts of immune system , through interaction with their receptors ( 2 ) . ... | evidence showed that chemokines serve as pro - migratory factors for immune cells .
ccl3 , ccl4 and ccl5 , as the main cc chemokines subfamily members , activate immune cells through binding to cc chemokine receptor 5 or ccr5 .
macrophages , nk cells and t lymphocytes express ccr5 and thus , affected ccr5 expressio... |
the consumption of sports and energy drinks has gained high popularity among the
adolescent population , especially 18- to 35-year - olds in recent years .
although the purpose of those drinks is to enhance performance and
endurance and prevent dehydration for individuals involved in physical activity , they
ar... | objectives : this study evaluated the effect of sports and energy drinks on the surface
hardness of different composite resin restorative materials over a 1-month period .
material and methods : a total of 168 specimens : compoglass f , filtek z250 , filtek supreme , and premise
were prepared using a customized c... |
pi*z individuals have a severe deficiency of alpha-1 antitrypsin ( aat ) and are genetically susceptible to developing chronic obstructive pulmonary disease ( copd ) ( black and kueppers 1978 ; larsson , 1978 ; tobin et al 1983 ; janus et al 1985 ; brantly et al 1988 ; silverman et al 1989 ) particularly with personal ... | backgroundin an early study of highly symptomatic patients with pi*z alpha-1 antitrypsin deficiency ( aat ) , tobacco smoking was identified as a risk factor by comparing the age of symptom onset in smokers and nonsmokers .
age of symptom onset has not been well studied in relationship to other environmental exposure... |
primary health care ( phc ) addresses the main health problems in the community , providing promotive , preventive , curative , and rehabilitative services accordingly .
the alma - ata declaration has outlined the eight essential components of phc and provision of essential medicines is one among them .
they are se... | the present study was undertaken to assess the availability of the essential medicines to the people of kunijarla , khammam district , ap .
this was done in two steps : 1 ) comparison of phc - eml ( primary health care essential medicines list ) with ap - eml ( andhra pradesh essential medicines list ) and neml ( nat... |
somatic cells are in constant risk of cancer transformation and organisms are endowed with surveillance mechanisms carried out by the immune system to control the generation of cancer cells .
these mechanisms are ( i ) controlling infection by oncogenic pathogens , ( ii ) resolving local inflammation to prevent the e... | experimental and clinical studies indicate that cells of the innate and adaptive immune system have both anti- and pro - tumor activities .
this dual role of the immune system has led to a conceptual shift in the role of the immune system 's regulation of cancer , in which immune - tumor cell interactions are underst... |
heks were maintained in epilife medium supplemented with human keratinocyte growth supplement ( hkgs ) consisting of 0.2 ng ml human recombinant epidermal growth factor ( egf ) , 0.18 g ml hydrocortisone , 5 g ml insulin , 5 g ml transferrin , and 0.2% ( v / v ) bovine pituitary extract .
cell cultures wer... | a comprehensive gene expression analysis of human melanocytes was performed assessing the transcriptional profile of dark melanocytes ( dm ) and light melanocytes ( lm ) at basal conditions and after uv - b irradiation at different time points ( 6 , 12 and 24 h ) , and in culture with different keratinocyte - conditio... |
ever since einstein developed his field equations of general relativity , defining gravitational energy and momentum in a consistent manner has been a perplexing conundrum .
while other forms of energy and momentum can be defined locally through the stress - energy tensor , gravitational energy does not readily lend ... | we explore the issue of gravitational energy localization for static plane - symmetric solutions of the einstein - maxwell equations in 3 + 1 dimensions with asymptotic anti - de sitter behavior .
we apply three different energy - momentum complexes , the einstein , landau - lifshitz , and mller prescriptions , to th... |
superior mesenteric and celiac artery aneurysm accounts for only 45.5% of all reported visceral artery aneurysms with an estimated incidence of 0.12% in the literature [ 1 , 2 ] .
furthermore , the majority of the reported cases are degenerative in nature . their mycotic ( infective cause ) occurrence is rare , and a... | visceral artery aneurysms as a result of arterial degenerative disease are rare ( 0.12% ) , and superior mesenteric artery ( sma ) accounts for 3.2% of all reported series .
however , mycotic sma aneurysms ( smaas ) are even rarer , and to the best of our knowledge , this is the first report of cryptogenic mycotic an... |
critical care is about specialized and dedicated care given by a team to a patient who is seriously ill .
it not only improves the chances of patients with desperate illness but also likes to promote an improvement in the general level of medical and nursing care .
critically ill patients are treated with a large n... | objective : to analyze clinical pharmacist interventions in the intensive care units ( icus ) setting of a tertiary care indian hospital and to assess the pharmacoeconomic impact on drug - related problems ( drps).materials and methods : a postgraduate clinical pharmacist reviewed drug prescriptions over a period of 7 ... |
metabolic syndrome ( mets ) is a constellation of interrelated metabolic risk factors that appear to directly promote the development of diabetes and cardiovascular diseases.1 identification of biomarkers associated with mets and diabetes is desirable to establish screening programs , preventive interventions , and the... | objectivethe current study was designed to perform deep analyses of the associations of biomarkers , including high - sensitivity c - reactive protein ( hs - crp ) , n - terminal prohormone of brain natriuretic peptide ( nt - probnp ) , and homocysteine ( hcy ) , with insulin resistance ( ir ) , metabolic syndrome ( me... |
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