article stringlengths 0 826k | abstract stringlengths 174 4.34k |
|---|---|
the natural history of giant intracranial aneurysms includes high morbidity and mortality from rupture.27 ) symptomatic lesions can be present in 50% of rupture cases , and the mortality rate is 60% in two years.6 ) these aneurysms are often found in the cavernous and paraclinoid segments of the internal carotid artery... | the pipeline embolization device ( ped ) is a braided , tubular , bimetallic endoluminal implant used for occlusion of intracranial aneurysms through flow disruption along the aneurysm neck .
the authors report on two cases of giant internal carotid artery aneurysm treated with the ped . in the first case ,
an aneu... |
group b streptococcus ( gbs ) was first recognized as a virulent pathogen responsible for most cases of neonatal sepsis in 1964 . since then
, gbs has been associated with neonatal meningitis , pneumonia , septic abortions , and chorioamnionitis .
it has also been implicated in puerperal sepsis , endometritis , and... | objective . to test the hypothesis that maternal obesity is an independent risk factor for rectovaginal group b streptococcus ( gbs ) colonization at term . study design .
retrospective cohort study of consecutive women with singleton term pregnancies admitted in labor at barnes - jewish hospital ( 20042008 ) .
mat... |
it is defined as the non - specific response of the body to any factor that overwhelms or threatens to overwhelm the body s ability to maintain homeostasis .
( 1 ) stress can make adolescents developing vulnerable to reach a biological and psychology maturity ; ( 2 ) however , a stress - free life is not suitable f... | background : many adolescents suffer from common mental disorders such as stress , which affects health through the psychosocial process , eating behavior , food choices and physical activity . during adolescence , dietary patterns are formed and can affect the occurrence of diseases in later life .
this is a review ... |
poor oral health and loss of teeth adversely affects the dietary intake and nutritional status and thereby compromises the general health .
the elders in old age homes are mainly those who have been abandoned by their family and have one or more physical or mental disabilities , such subjects experience anxiety , dep... | introduction : elders in old age homes are mainly those who have been abandoned by their family and have one or more physical or mental disabilities .
it is a major challenge for the dental professional to plan oral health strategy for this group of patients.aim of the study : aim of the present study is to observe a... |
post - op 2 day , she began passive range of motion ( rom ) and isometric strengthening exercises in the physical therapy department .
home exercises were given twice a day and each exercise was done with 20 repetitions .
a cold pack was applied after exercise in the clinic and was recommended for application at ho... | we report a 66-year - old woman with complex regional pain syndrome ( crps ) 1 treated with combined medical and active physical therapy .
she was diagnosed with crps 1 following partial shoulder prosthesis due to proximal humerus fracture . despite continuous medication and physical therapy
, there was no improvem... |
epigenetic silencing via an antisense - mediated mechanism has been observed at the x - inactive specific transcript ( xist ) and tsix antisense locus ( 1 ) as well as for imprinted genes such as insulin - like growth factor - type-2 receptor ( igf2r ) ( 2 ) and the potassium voltage - gated channel , kqt - like subfam... | angelman syndrome ( as ) is a neurogenetic disorder characterized by severe mental retardation , puppet - like ataxic gait with jerky arm movements , seizures , eeg abnormalities , hyperactivity and bouts of inappropriate laughter .
individuals with as fail to inherit a normal active maternal copy of the gene encodi... |
the corneal endothelial cell density is essential in the clinical assessment of the cornea to determine its function and ability to respond to stress .
it is important to determine a reference range for different population groups in order to establish abnormal values and aid predictability , especially with the note... | aimthe aim of the study was to describe the corneal endothelial cell density of adults at the mecure eye center and to determine the relationship between age , sex , and corneal endothelial cell density.methodsthis study was a retrospective study looking at those records of individuals who had undergone specular micros... |
a baby boy weighing 2930 g delivered via cesarean section at 36 gestational week to a g2p2 mother was admitted to our intensive care unit with initial diagnosis of duodenal atresia .
the first evaluation of his postnatal radiogram which demonstrated a double - bubble image could not disclose any additional pathology ... | our aim is to present a case with initial diagnosis of non - classified type duodenal atresia operated in our clinic .
a patient with prenatally suspected to be duodenal atresia was explored . at laparotomy
type 3 duodenal atresia was found between 2nd and 3rd parts of duodenum .
in addition , a web was detected ... |
a 38-year - old woman visited our hospital complaining of progressive hypesthesia in the right lower limb and weakness in the left lower limb . she had noticed decreased sensation in the right lower limb 3 years previously when she took a hot bath , and had felt motor weakness in the left lower limb on walking or climb... | idiopathic spinal cord herniation is a rare spinal cord disorder caused by spinal cord prolapse through a adural defect .
it is a curable disease , so early detection is of particular importance .
we report a 38-year - old woman with brown - sequard syndrome which was caused by the thoracic spinal cord herniation .... |
hepatocellular carcinoma ( hcc ) comprises 90% of the liver tumors occurring worldwide in humans , with more than half a million new cases reported every year .
diagnosis of this cancer , once restricted mostly to asia , is now rising in europe as well as in north america .
environmental factors , such as hepatitis... | bicyclol , an antihepatitis drug developed by chinese scientists , has been shown to prevent the malignant transformation induced by 3-methylcholanthrene and 12-o - tetradecanoylphorbol-13-acetate in wb - f344 rat liver epithelial cells .
this study provides further evidence on its role as a chemopreventive agent in ... |
helicobacter pylori is a gram - negative comma shaped bacterium , which can cause chronic or acute gastritis , gastric and duodenal ulcers , gastric adenocarcinoma , and mucosa associated lymphoid tissue ( malt ) lymphoma .
although most infected individuals may remain asymptomatic ( 1 ) , h. pylori is colonized in m... | background : helicobacter pylori infection and related diseases outcome are mediated by a complex interplay between bacterial , host and environmental factors . several distinct virulence factors of h. pylori have been shown to be associated with different clinical outcomes .
here we focused on vaca and caga genotype... |
ascariasis , caused by the nematode ascaris lumbricoides , is the commonest helminthic infection among humans
. the infection spreads via the faeco - oral route and hence its prevalence is more in the tropical and subtropical developing countries , which are ravaged by the problems of poverty , overcrowding and poor ... | ascariasis is the commonest helminthic infection in humans , caused by the nematode ascaris lumbricoides .
the adult worms usually reside in the small intestine .
rarely , they migrate into the bile duct and pancreatic ducts , but involvement of the gall bladder and/or liver parenchyma is extremely rare . here , we... |
the increased prevalence of food allergies is a significant clinical and public health problem in the usa .
it is estimated that in the usa alone , food - allergic reactions accounted for over 20,000 emergency department visits , 2,300 episodes of anaphylaxis , and over 500 hospitalizations over just a 2-month peri... | proteomic profiles of rast+ subjects with severe food allergies and rast subjects were compared using 2d - dige analysis to obtain candidate biomarkers specific to food allergies .
our analysis highlighted 52 proteins that were differentially expressed between the rast+ and rast groups of which 37 were successfully i... |
despite improvement in the prognosis of patients with cardiovascular disease ( cvd ) it still remains the second leading cause of death across the western world and one of the major causes of disability . for many years patients with coronary artery disease ( cad ) ,
the most frequent type of cvd , were treated mainl... | aimvariations in treatment are the result of differences in demographic and clinical factors ( e.g. anatomy ) , but physician and hospital factors may also contribute to treatment variation .
the choice of treatment is considered important since it could lead to differences in long - term outcomes .
this study expl... |
nicotinic acetylcholine receptors ( nachrs ) , to which nicotine binds , serve as the gateways through which nicotine exerts its effects on the brain .
recent years have witnessed a rapid growth in research focused on the nachr gene cluster chrna5-a3-b4 on the long arm of chromosome 15 ( 15q24 - 25.1 ) , responsibl... | introduction : the nicotinic acetylcholine receptor ( nachr ) gene cluster chrna5-a3-b4 on chromosome 15 has been the subject of a considerable body of research over recent years . two highly correlated single nucleotide polymorphisms ( snps ) within this region rs16969968 in chrna5 and rs1051730 in chrna3have generat... |
graves disease is an autoimmune disease caused by autoantibodies ( thyrotropin ( tsh ) receptor antibodies - tshr - ab ) that activate the tsh - receptor ( tshr ) , thereby , stimulating thyroid hormone synthesis and secretion , and thyroid growth ( causing a diffusely enlarged goiter ) .
the resulting state of hyper... | objective : two approaches are used to treat graves disease with radioiodine ( 131i)the fixed dose approach and the other based on dosimetry . a prospective study was performed to compare the results of these two approaches in a randomized patient population , as such study is lacking in the indian population till date... |
they are composed of dense cortical bony structure and minimal amount of bone marrow , and are covered with a fragile and limited vascularized mucosa .
tori usually become apparent during the second or third decade of life.1 tori may develop at the midline of palate ( torus palatinus [ tp ] ) or the lingual aspect of... | backgroundthe most remarkable exostoses of the human jaws are torus palatinus ( tp ) and torus mandibularis ( tm ) .
the aim of the present study was to actuate the prevalence of tp and tm in relation to age and sex among the edentulous patients of saudi arabia.methodsthe present study included 847 edentulous subject... |
fibroadenoma is the most common breast tumor in women and is characterized by proliferation of both epithelial and stromal components of the terminal ductal unit .
women can present with fibroadenoma at any age , but the peak incidence is in the second and third decades of life .
fibroadenomas expand in the presenc... | fibroadenoma is the most common breast tumor in women .
malignant transformation occurs rarely within fibroadenoma at older ages .
clinicians , radiologists , and pathologists need to be aware of malignant transformation within fibroadenomas .
radiologic studies play an important role in the diagnosis of fibroade... |
shortwave infrared ( swir or nir - ii )
light provides significant advantages for imaging biological structures
due to reduced autofluorescence and photon scattering . here , we report
on the development of rare - earth nanoprobes that exhibit swir luminescence
following x - ray irradiation .
we demonstrate t... | |
when slow gradual occlusion happens as like in perihilar cholangiocarcinoma , such dilatation becomes insidious thus showing diffuse dilatation of the involved intrahepatic bile ducts .
in contrast , if rapid gradual occlusion is associated with friable liver parenchyma such as rapidly regenerated remnant livers or p... | we herein present a case of spontaneous rupture of intrahepatic bile duct in a patient with perihilar cholangiocarcinoma , which were successfully treated by curative resection . a 60-year - old male patient with perihilar cholangiocarcinoma
was decompressed with single percutaneous transhepatic biliary drainage .
... |
fluorescent lighting technologies are undergoing rapid market growth as part of a resurgent societal interest in energy efficiency .
much of current and projected growth is in the domestic use of compact fluorescent lamps ( cfls ) , which offer consumers approximately 75% reduction in energy usage and 10-fold increas... | the projected increase in the use of compact fluorescent lamps ( cfls ) motivates the development of methods to manage consumer exposure to mercury and its environmental release at the end of lamp life .
this work characterizes the time - resolved release of mercury vapor from broken cfls and from underlying substrat... |
it prevents further development of the root , leaving a tooth with thin root walls .
conventional root canal treatment techniques used in mature teeth are difficult to use in immature teeth which have various anatomical complexities .
the instrumentation and obturation of immature root canals are difficult or impos... | revascularization of immature necrotic teeth is a reliable treatment alternative to conventional apexogenesis or apexification . in case 1 ,
a 12-year - old boy had his necrotic , immature mandibular left second premolar treated with a revascularization technique . at a 24-month follow - up ,
periapical radiolucenc... |
a serious complication of heparin treatment , heparin - induced thrombocytopenia ( hit ) is rarely observed in pregnant women .
, the anticoagulants used in patients with hit do cross the placenta , with unknown fetal effects .
we present a case of a 24-year - old female presenting for care at 34 weeks of gestation... | summarybackgrounda serious complication of heparin treatment , heparin - induced thrombocytopenia ( hit ) is rarely observed in pregnant women .
drug therapy during pregnancy should always be chosen to minimize fetal risk .
the management of hit in pregnancy represents a medical challenge . unlike heparins
, the ... |
ground - state enamine chemistry has been
extensively explored since
the 1950s . following pioneering studies by gilbert stork , organic
chemists have exploited enamines nucleophilic character to
trap electrophiles and develop useful two - electron polar processes .
successively , chiral enamines i ,
genera... | herein
we describe our efforts to elucidate the key mechanistic
aspects of the previously reported enantioselective photochemical
-alkylation of aldehydes with electron - poor organic halides .
the chemistry exploits the potential of chiral enamines , key organocatalytic
intermediates in thermal asymmetric pr... |
for this study , we monitored changes in antimicrobial resistance in different hospital areas during two periods ( 19961997 and 19981999 ) in facilities participating in project icare ( intensive care antimicrobial resistance epidemiology ) , a joint project of the hospital infections program ( now the division of heal... | antimicrobial resistance is increasing in nearly all health - care associated pathogens .
we examined changes in resistance prevalence during 19961999 in 23 hospitals by using two statistical methods .
when the traditional chi - square test of pooled mean resistance prevalence was used , most organisms appear to h... |
first , a person must have symptoms severe enough for medical care ( multiplier 1 ) .
second , the physician must collect patients specimens ( multiplier 2 ) and forward them for testing by bacterial culture ( multiplier 3 ) .
third , the sample test result must be positive ( multiplier 4 ) , and the confirmed case... | we used active and passive surveillance to estimate nontyphoidal salmonella ( nts ) infection during 2012 in guangdong province , china . under passive surveillance , for every reported nts infection , an estimated 414.8 cases occurred annually . under active surveillance , an estimated 35.8 cases occurred .
active s... |
ulnar neuropathy is the second most common cause of entrapment neuropathy after carpal tunnel syndrome .
the ulnar nerve could be trapped in every part of upper limb including wrist , elbow , or arm .
therefore , diagnosing the site of ulnar nerve injury is of great clinical and therapeutic importance .
ulnar neu... | aim . to evaluate the diagnostic value of ultrasonography and magnetic resonance imaging ( mri ) in patients with ulnar neuropathy at the elbow ( une )
. methods .
we prospectively performed electrodiagnostic , ultrasonographic , and mri studies in une patients and healthy controls .
three cross - sectional area ... |
culprit lesions , the treatment of which is the primary goal of percutaneous coronary intervention ( pci ) , have been studied for decades and have been found to be responsible for most of the adverse events of acs , while other plaques , which are referred to as non - culprit lesions ( nccls ) , are considered to be i... | backgroundthe influence of homocysteine ( hcy ) on the migration and proliferation of vascular smooth muscle cells has been well established
. however , the impact of hcy levels on the progression of non - culprit coronary lesions ( nccls ) is controversial .
this study aims to evaluate whether the plasma level of ... |
in 1977 , the national center for health services research conducted the most comprehensive survey of health insurance and use of health care services in this nation 's history . from this survey emerged a vivid picture of the american health care system in the 1970's a system almost entirely financed by conventional ... | in this article , the 1987 conventional health plans are examined and 1987 group health insurance is compared with that of 1977 . the source of information for 1987 is the national survey of 771 private and public employers conducted by the health insurance association of america .
data for 1977 are from the national... |
given the low survival rate for cardiac arrest both in the field and in hospital , it would be useful to have rapid , noninvasive means to guide treatment and predict outcome .
early studies of end - tidal carbon dioxide tension ( etco2 ) monitoring and bedside cardiac sonography have shown great promise in predictin... | emergency physicians and intensivists are increasingly utilizing capnography and bedside echocardiography during medical resuscitations .
these techniques have shown promise in predicting outcomes in cardiac arrest , and no cases of return of spontaneous circulation in the setting of sonographic cardiac standstill an... |
this study is part of an ongoing project whose long - term goal is to evaluate t1 mri as a quantitative , noninvasive biomarker of disk degeneration in patients with lbp .
volunteers were recruited from three cohorts : patients being treated for lbp ( n = 12 , 49 levels , mean age 44 6 years , range 30 to 53 ) whose... | t-1-rho ( t1 ) magnetic resonance imaging ( mri ) and disc height ratio ( dhr ) are potential biomarkers of degenerative disk disease ( ddd ) related to biochemical composition and morphology of the intervertebral disk ( ivd ) , respectively .
to objectively detect ddd at an early stage , the hypothesis was tested th... |
cryptosporidium spp . are common causes of gastroenteritis in human and a wide range of mammalian hosts ( 1 ) .
oocyst shedding from livestock animals has been a contamination source for human cryptosporidiosis outbreaks ( 2 ) .
cryptosporidium spp . , is a complex of morphologically similar but genetically differe... | background : as a waterborne pathogen , cryptosporidium is one of the most common causes of gastroenteritis in human and hoofed livestock animals .
this study aimed to investigate the distribution of cryptosporidium spp . in human and livestock wastewaters in iran , by the 18s rrna sequence analysis.methods:a total o... |
cognitive dysfunction frequently occurs following stroke and is an important cause of stroke - related morbidity .
the treatment of cognitive impairment and prevention of further decline are essential aspects of stroke rehabilitation .
however , there is only limited evidence to suggest beneficial effects of physic... | backgroundno drug treatment to date has shown convincing clinical evidence of restoring cognitive function or preventing further decline after stroke .
the ongoing artemida study will evaluate the efficacy and safety of actovegin for the symptomatic treatment of post - stroke cognitive impairment ( psci ) and will ex... |
cyclooxygenases ( coxs ) are the key enzymes in the conversion of arachidonic acid to prostaglandins .
cox-1 is constitutively expressed in most tissues and produces prostaglandins for homeostatic functions ( 1 , 2 ) .
cox-2 is highly inducible at inflammation sites and is associated with various human tumors such ... | to evaluate the expressions of cyclooxygenase-2 ( cox-2 ) and inducible nitric oxide synthase ( inos ) in thyroid neoplasms in a korean population , we studied a total of 154 cases : papillary carcinoma of classical type ( ptc ) , 86 ; follicular adenoma ( fa ) , 21 ; follicular carcinoma ( fc ) , 35 ; medullary carcin... |
abnormalities of the cardiac valves are common in patients with end - stage renal disease ( esrd ) .
mitral and aortic calcification is seen in 1055% of patients with esrd [ 15 ] .
surgical valve replacement for symptomatic patients is indicated for those of acceptable risk , but there are others who are unsuitable... | valvular heart disease is common in patients with end - stage renal disease and , if symptomatic , may lead to valve replacement surgery .
however , some patients with renal failure are deemed unsuitable for cardiac surgery , and in those patients who do undergo surgery , there is a significantly greater morbidity an... |
the world health organization estimates
285 million persons have visual impairments in the world , with 39
million completely blind .
primary educators
have been apprehensive in providing a science , technology , engineering
and mathematics ( stem ) education to blind students .
adaptation of laboratory exe... | there
exists a sparse representation of blind and low - vision students in
science , technology , engineering and mathematics ( stem ) fields .
this
is due in part to these individuals being discouraged from pursuing
stem degrees as well as a lack of appropriate adaptive resources in
upper level stem course... |
various inflammatory mediators produce joint inflammation with pain function loss , joint destruction and permanent deformity after certain time if left untreated .
the prevalence of rheumatoid arthritis is consistent worldwide affecting about 0.5 - 1.0% of the population .
the first stage is the swelling of the sy... | objective : costus speciosus koen .
( keu , crape ginger ) , an ornamental plant , widely distributed in india is traditionally used as astringent , aphrodisiac , purgative , anthelmintic , depurative , febrifuge and expectorant .
the plant is also used in rheumatism , dropsy , urinary diseases and jaundice .
the... |
the reduced rate of
success experienced in the treatment of furcation involvements seems to result from the
incomplete removal of subgingival plaque and calculus in the interadicular area owing to
the peculiar anatomy of the furcation space . in addition , the
distal location and the specific root configuration... | objectivethe aim of this controlled clinical trial was to evaluate the effect of topically
applied povidone - iodine ( pvp - i ) used as an adjunct to non - surgical treatment of
interproximal class ii furcation involvements . material and methodsthirty - two patients presenting at least one interproximal class ii ... |
hyperuricemia is a predisposing factor for gout , which is a common inflammatory joint disease affecting 0.08% of the population worldwide.1 previous clinical studies have uncovered a significant association between parathyroid hormone ( pth ) and uric acid level in humans.2,3 hyperuricemia has been found in patients s... | backgroundprevious reports of patients undergoing parathyroidectomy and of patients receiving teriparatide as antiosteoporotic treatment have suggested a plausible relationship between parathyroid hormone ( pth ) and uric acid .
however , similar data at population level were lacking . the current study aimed to dete... |
despite advances in detection and management , cervical cancer continues to be a significant health problem on a worldwide scale .
cervical cancer is the most frequent type of cancer in women in many developing countries .
the most widely accepted staging system for tumors of the cervix is that of the international... | cervical cancer is the most frequent type of cancer in women in many developing countries .
squamous cell carcinoma of the cervix spreads principally by lymphatics and less commonly through blood vessels .
the most frequent sites for those who develop distant metastasis include lungs ( 21% ) , lumbar and thoracic s... |
metabolomics is comprehensive analysis of the repertoire of biochemicals that are present in cells , tissues , and body fluids and represents individuals overall health status ( nicholson and lindon 2008 ) .
metabolomic findings are influenced by the genome , diet , drugs , environmental factors , and the gut microbi... | the landscape of newborn screening ( nbs ) is changing as new tools are developed .
we must acknowledge that nbs is a very important and extraordinarily positive initiative especially for rare and serious inherited disorders ; however , lessons learned from current nbs should guide the future of nbs as we enter the e... |
it has been demonstrated that ~35% of patients undergoing surgery have an acquired platelet defect , a congenital platelet defect or von willebrand disease.1 ongoing and postoperative bleeding are the most frequent complications in patients undergoing functional endoscopic sinus surgery ( fess ) or septoplasty.2 intrao... | backgroundit is necessary to predict the bleeding risk in patients undergoing functional endoscopic sinus surgery ( fess ) . to evaluate the adequacy of primary hemostasis ,
preoperative hemostatic screening tests are used . in the present study
, we determined whether there is a positive correlation between prolon... |
as in many fields of neuropsychology , the study of multisensory processing dysfunctions in brain - lesioned patients has been of invaluable help in better understanding the mechanisms and functional roles of multisensory perception and integration in human cognition . in particular , crossmodal
extinction has consti... | the study of crossmodal extinction has brought a considerable contribution to our understanding of how the integration of stimuli perceived in multiple sensory modalities is used by the nervous system to build coherent representations of the space that directly surrounds us .
indeed , by revealing interferences betwe... |
it has many functions , one of the major functions being protection of teeth against dental caries .
there are many components in saliva , each one having a specific role in the prevention of dental caries .
whole saliva is a product of secretion of three major glands ( parotid , submandibular , and sublingual ) an... | introduction : reduction of functioning minor salivary glands may contribute to emergence of mucosal infections , mucosal ulceration , and possibly dental caries .
a study was , therefore , designed to understand the exact role of minor salivary gland secretions over dental caries.methodology:we studied the average l... |
kawasaki disease is generalized systemic vasculitis.1 ) many head and neck symptoms and signs are manifested in kawasaki disease such as bilateral nonexudative conjunctivitis , erythema of the lips , and oral mucosa and cervical lymphadenopathy .
but parotitis is a very uncommon manifestation of kawasaki disease , ev... | a male infant aged 3 months and 1 week had persistently high fever with parotitis that was unresponsive to antibiotics .
mumps was identified by serologic study , but he was finally diagnosed by clinical features as having kawasaki disease and echocardiographic findings on the 9th day of fever .
parotitis , which i... |
non - hodgkin s lymphomas ( nhl ) arise most frequently in lymph nodes or other lymphatic tissues .
primary extranodal lymphomas account for 20 - 34% of all cases of nhl nevertheless primary extranodal lymphomas arising in the genital tract are very rare .
the national cancer database report on nhl in 1997 , which ... | a 52-year - old woman was referred to the gynecology outpatient clinic with a 2 months history of vaginal bleeding with intercourse , and no other symptoms .
vaginal examination revealed a firm , non - tender , mass in the posterior vaginal wall .
the initial clinical impression was that of a vaginal carcinoma and ... |
the eua guidelines on male infertility defined obstructive azoospermia as absence of both spermatozoa and spermatogenic cells in semen and postejaculate urine due to bilateral obstruction of the seminal ducts . the male infertility best practice policy committee of the american urologic association reported that 10%15%... | about 10%15% of infertile men present with azoospermia , and ductal obstruction is the cause in 40% of them . for about 2530 years , microsurgical reconstruction was the only way to manage obstructive azoospermia , and several innovative techniques have been developed and implemented . presently , assisted reproductive... |
this report aims to describe the clinical and epidemiologic features of nov infection in children hospitalized for enteritis and to compare the severity score related to the different viral agents and nov genotypes . from january to december 2004 , 390 fecal specimens were obtained from 365 children with acute gastroen... | noroviruses were detected in 48.4% of 192 children
( <3 years of age ) hospitalized for gastroenteritis in palermo , italy , during 2004 ; predominant genotypes were ggiib / hilversum and ggii.4 hunter . of children with viral enteritis ,
19.6% had a mixed norovirus - rotavirus infection .
the severity of infecti... |
leishmaniasis is a potential threat to human population in 88 countries affecting around 12 million people globally ( 1 ) . around l,500,000 cases of cutaneous leishmaniasis ( cl )
has been reported from tropical , subtropical and temperate regions of many countries each year .
it is more widely distributed in thre... | backgroundcutaneous leishmaniasis is an annoying and disfiguring disease affecting around 1,500,000 individuals globally .
there are endemic pockets of this disease in taif region . in some patients
, lesion often weeps and leads to scar formation .
the study was conducted to see the efficacy of fluconazole and i... |
the dataset used comprised 1,149 new caucasian type 1 diabetes multiplex families combined with a number of existing type 1 diabetes dna collections that are largely caucasian , some of which have previously been hla typed and analyzed ( 20,23 ) , including the danish ( n = 95 ) , human biological data interchange ( hb... | objectiveto determine the relative risk associated with dpa1 and dpb1 alleles and haplotypes in type 1 diabetes.research design and methodsthe frequency of dpa1 and dpb1 alleles and haplotypes in type 1 diabetic patients was compared to the family based control frequency in 1,771 families directly and conditional on hl... |
pandemic ( h1n1 ) 2009 virus ( a / netherlands/602/2009 ) was isolated from a 3-year - old girl from the netherlands who had mild influenza after she visited mexico in early 2009 .
virus was cultured in embryonated chicken eggs and passaged once in mdck cells ( 7 ) .
we used 2 groups ( 4 cats / group ) of 16-week -... | to demonstrate that pandemic ( h1n1 ) 2009 virus may cause respiratory disease in cats , we intratracheally infected cats . diffuse alveolar damage developed .
seroconversion of sentinel cats indicated cat - to - cat virus transmission . unlike in cats
infected with highly pathogenic avian influenza virus ( h5n1 ) ... |
benign prostatic hyperplasia ( bph ) is one of the most common diseases among elderly males . today
, with the trend toward a decreased incidence of surgery and a growing demand for medical therapy , medical doctors other than urologists may be responsible for the diagnosis and management of bph treatment . in europe... | purposeto compare the current management of benign prostatic hyperplasia ( bph ) by urologists and nonurologists by use of korean nationwide health insurance data.materials and methodswe obtained patient data from the national health insurance system .
new patients diagnosed with bph in 2009 were divided into two gro... |
the contribution of fat content of meat to overall meat palatability has been established for decades .
savell and cross ( 1988 ) established a window of acceptability for beef ( fig .
1 ) , indicating that overall palatability of beef is optimal between 3 and 7.5% intramuscular lipid . increasing intramuscular lip... | this review addresses the role of fat in beef palatability and healthfulness .
particular emphasis is placed on the content of oleic acid in beef , and how this increases with time when cattle are fed a grain - based diet .
oleic acid decreases the melting point of lipids from beef , increasing the perception of ju... |
behet 's disease ( bd ) is a chronic and relapsing multisystemic inflammatory disorder which can be localized on the borderline between autoimmune and autoinflammatory diseases .
its incidence is increased around the mediterranean basin , extending through middle east and orient countries , and from a clinical point ... | behet 's disease ( bd ) is universally recognized as a multisystemic inflammatory disease of unknown etiology with chronic course and unpredictable exacerbations : its clinical spectrum varies from pure vasculitic manifestations with thrombotic complications to protean inflammatory involvement of multiple organs and ti... |
more than 800,000 women are diagnosed with breast cancer approximately , and an estimated 65% to 75% of the patients with advanced metastases will develop bone metastases during the course of their disease . over the past few years
, many studies had shown that bone metastases are common in patients with breast cance... | objectives . we aim to determine the efficacy of bisphosphonates in preventing aromatase inhibitor induced bone loss ( aibl ) in postmenopausal women with early breast cancer .
the secondary objective was to determine the safety of bisphosphonates .
materials and methods .
we searched electronic databases in a ti... |
although the world health organization ( who ) and its member states across the world have aimed to eliminate measles , the elimination has been so far fully successful only in the north american region . as the transmission potential of measles is extremely high with the estimated basic reproduction number of the orde... | as part of measles elimination effort , evaluation of the vaccination program and real - time assessment of the epidemic dynamics constitute two important tasks to improve and strengthen the control .
the present study aimed to develop an epidemiological modeling method which can be applied to estimating the vaccine ... |
drug - induced liver injury ( dili ) is a major health problem that poses a challenge not only to health care professionals , but also the pharmaceutical industry and drug regulatory agencies . according to the united states acute liver failure study group , dili accounts for more than 50% of acute liver failure , incl... | drug - induced liver injury is a major health problem .
its predominant forms include acute hepatitis , cholestasis , and a mixed pattern .
ceftriaxone is a third - generation cephalosporin and is widely used in the postoperative period due to its wider spectrum , longer half - life , and better tissue penetrabilit... |
pain is a common condition and has a significant influence on the quality of life .
it was defined by the international association for the study of pain ( iasp ) as an unpleasant sensory and emotional experience associated with actual or potential tissue damage , or described in terms of such damage .
the concep... | pain represents a complex experience which can be approached by various medicines .
non - opioid and opioid analgesics are the most common drugs used to manage different types of pain .
the increased attention nowadays to pain management entailed concomitantly more frequent adverse drug reactions ( adrs ) related t... |
echocardiography , computed tomography ( ct ) and magnetic resonance imaging ( mri ) may be used as summative diagnostic tools to support correct diagnosis .
however , most malignant pericardial mesotheliomas have been diagnosed by histology , including immunohistochemical staining , after surgery or autopsy . to det... | malignant pericardial mesothelioma is a rare and progressive cardiac tumor .
there is no established standard treatment and the prognosis is poor .
most patients were retrospectively diagnosed from surgery or autopsy due to absence of specific clinical manifestation .
most patients with pericardial mesothelioma h... |
they function without an external source of energy and by a gravity independent mechanism.1,2 they take up little space , are light and preserve patient mobility .
they have no maintenance costs and are without risk of presenting an erroneous flow rate . among them , diffusers with a balloon ( reservoir ) or elastome... | the use of elastomeric diffusers ( eds ) has grown together with the expansion of home care . in these devices ,
the fill volume of the drug reservoir and the flow rate are preset and can not be modified .
the elastomer , which makes up the reservoir walls , is what makes the infusate flow due to the pressure it ex... |
the goal of introducing metal probes into a narrow lumen is to judiciously stretch , calibrate , and unblock narrowings without producing additional scarring .
it may be curative in patients with isolated epithelial strictures ( no involvement of corpus spongiosum ) .
urethral stricture is a term commonly used for ... | objectivesto present our center 's experience in managing bladder outlet obstruction ( boo ) conditions using bougie dilators .
we described the dilation technique methodically for teaching purpose.patients and methodretrospectively , a total of 196 medical records over the last four years denoting boo conditions in ... |
the progressive pathological changes post - myocardial infarction ( mi ) include an initial inflammatory response , loss of cardiomyocytes [ 2 , 3 ] , and degradation of the left ventricular ( lv ) extracellular matrix ( ecm ) by matrix metalloproteases [ 4 , 5 ] , which lead to wall thinning , infarct expansion , scar... | cardiovascular disease continues to be the leading cause of death , suggesting that new therapies are needed to treat the progression of heart failure post - myocardial infarction . as cardiac tissue
has a limited ability to regenerate itself , experimental biomaterial therapies have focused on the replacement of nec... |
we conducted a prospective , multicenter study during december 1 , 2009december 31 , 2010 , by recruiting a convenience sample of msm at sentinel sites for sexually transmitted infections throughout germany .
inclusion criteria were being msm , having > 1 male sexual partner within the previous 6 months , and agreein... | to determine prevalence of lymphogranuloma venereum among men who have sex with men in germany , we conducted a multicenter study during 20092010 and found high rates of rectal and pharyngeal infection in men positive for the causative agent , chlamydia trachomatis .
many infections were asymptomatic . an adjusted c.... |
pleura is divided into a parietal layer which lines the inner aspect of the chest wall and a visceral layer which covers the interlobar fissures .
the mean amount of pleural fluid in the normal is as small as 8.4 4.3 ml .
fluid that enters the pleural space can originate in the pleural capillaries , the interstit... | the aim is to examine whether the interleukin-1 ( il-1 ) , il-2 , il-6 , tumor necrosis factor- ( tnf- ) , plasminogen activator inhibitor type-1 ( pai-1 ) , and tissue plasminogen activator ( t - pa ) levels were different in pleural effusions of tuberculous pleurisy and tuberculous empyema .
il-1 , il-2 , il-6 , tn... |
an association between type 2 diabetes mellitus ( t2 dm ) and nonalcoholic fatty liver disease ( nafld ) , which describes a wide spectrum of liver disorders from steatosis to cirrhosis , has long been recognized [ 13 ] .
much attention was given to this entity in patients with t2 dm , but little is known about the e... | purpose .
this study evaluated the long - term effects of alloxan - induced diabetes in rat liver . methods .
thirty nondiabetic control rats ( nc ) and 30 untreated diabetic ( ud ) rats were divided into three subgroups sacrificed after 6 , 14 , or 26 weeks .
clinical and laboratory parameters were assessed .
... |
theory helps scientists recognize interactions between social and biological factors that may affect population health and provides explanations for what is observed .
although traditional research uses theory - driven methods , little attention seems to be paid to theoretical foundations and conceptual frameworks fo... | objectivethis article discusses the need for theoretical foundations in epidemiological research of musculoskeletal conditions and suggests the use of biopsychosocial theory when designing epidemiological studies .
the association between smoking and back pain is used as an example.discussiontheory-driven musculoskel... |
protein fibers play a crucial role
in many disease related phenomena
and biological systems .
a structural analysis of fibrous proteins
often requires labeling approaches or disruptive sample preparation
while it lacks chemical specificity .
here we demonstrate that the
technique of vibrational sum - freq... | |
the test consists of 85 movable color samples arranged in four opaque boxes of 22 colors in the first box and 21 colors in each of the remaining 3 [ no . 85 - 21 , 22 - 42 , 43 - 63 , and 64 - 84 ] .
the hue samples were designed to represent perceptually equal steps of hue and to form a natural hue circle .
they a... | purpose : the farnsworth - munsell ( fm ) 100-hue test is well known but is also time consuming , especially its analytical component . to reduce this needless time - waste during precious working hours ,
a simple modification was devised.design:prospective , comparative , observational study.materials and methods : ... |
to study the effect of octreotide therapy on endometriotic lesions in a patient with coexisting endometriosis and acromegaly .
in this unusual case , the treatment of acromegaly concurred with regression in the endometriotic lesions . causal or incidental association can not be inferred from the present case . ... | objective : to study the effect of octreotide therapy on endometriotic lesions in a patient with coexisting endometriosis and acromegaly.intervention : patient : a 34-year - old female was diagnosed with acromegaly and coexisting endometriosis .
post - surgical resection of the tumor , patient was initiated on octreo... |
plasma samples from healthy pigs were collected in great britain in 2001 . initially , these samples were tested for parv4-like viruses by using previously described degenerate pcr primers ( 10 ) .
dna was extracted from samples by using the high pure dna isolation kit ( roche applied science , roche diagnostics cana... | porcine plasma and factor viii preparations were screened for parvovirus 4 ( parv)like viruses .
although the prevalence of parv4-like viruses in plasma samples was relatively low , viruses appeared to be concentrated during manufacture of factor viii .
parv4-like viruses from human and porcine origins coevolved li... |
the subfornical organ ( sfo ) , located in the anterior dorsal wall of the third ventricle , is one of the sensory circumventricular organs characterized by the presence of neurons and the lack of a normal blood brain barrier .
the neurons in the sfo may function as a sensory organ for the detection of the blood born... | the subfornical organ ( sfo ) is one of circumventricular organs characterized by the lack of a normal blood brain barrier .
the sfo neurons are exposed to circulating glutamate ( 60~100 m ) , which may cause excitotoxicity in the central nervous system .
however , it remains unclear how sfo neurons are protected f... |
shoulder pain has an incidence of 736% and is a common symptom of musculoskeletal disease ,
which occurs in20% of all adults once in their lifetimes1 .
shoulder pain may be caused by myofascial pain syndrome , disruption
of the rotator cuff , frozen shoulder , shoulder impingement syndrome , and damaged
ligamen... | [ purpose ] this study aimed to determine the effect of pain scrambler therapy on shoulder
joint pain and range of motion in patients who had undergone arthroscopic rotator cuff
repair for the first time .
[ subjects and methods ] pain scrambler therapy was administered
once a day every 40 minutes for 10 days t... |
endothelial cell dysfunction ( ecd ) is a broad term which implies dysregulation of endothelial cell functions , including impairment of the barrier functions of endothelial cells , vasodilation , disturbances in proliferative capacities , migratory as well as tube formation properties , angiogenic properties , attenua... | diabetes mellitus ( dm ) is a chronic metabolic disorder characterized by inappropriate hyperglycemia due to lack of or resistance to insulin .
patients with dm are frequently afflicted with ischemic vascular disease or wound healing defect .
it is well known that type 2 dm causes amplification of the atherosclero... |
he was diagnosed with lymphoblastic lymphoma and treated with a chemotherapeutic regimen ( hyper - cvad ) .
ten days after the chemotherapy , he became agitated and exhibited temporary whole - body tremor that made him unable to stand still . on examination , he appeared dull and apathetic , and his gait was slow and... | lymphomatoid granulomatosis ( lg ) is a potentially malignant lymphoproliferative disorder .
the lung is the most common involved site , followed by the skin and nervous system .
however , lg of the central nervous system presenting with parkinsonism is very rare .
we report a patient with lg who presented with p... |
flaxseed ( linum usitatissimum ) meal is the main byproduct from the flaxseed oil extraction process , being primarily used as a ruminant feed .
the meal is composed of three important fractions : proteins ( over 300 g kg ) , which are rich in arginine and glutamine ; amino acids that are very important in the prev... | flaxseed ( linum usitatissimum ) meal , the main byproduct of the flaxseed oil extraction process , is composed mainly of proteins , mucilage , and phenolic compounds . the extraction methods of phenolics either commonly employed the use of mixed solvents ( dioxane / ethanol , water / acetone , water / methanol , and w... |
the online version of this article ( doi:10.1007/s13539 - 012 - 0075 - 5 ) contains supplementary material , which is available to authorized users .
weight loss is commonly observed in several types of cancer , and poor nutritional status has been associated with decreased survival and poorer quality of life in ... | backgroundcancer can lead to weight loss , anorexia , and poor nutritional status , which are associated with decreased survival in cancer patients.methodsmale cancer patients ( n = 136 ) were followed for a mean time of 4.5 years .
variables were obtained at baseline : cancer stage , albumin , hemoglobin , tumor ... |
collaboration between the study center in jerusalem and 24 of the 25 acute - care hospitals in israel was coordinated with the infectious diseases consultant or the director of the microbiology laboratory at each hospital .
we provided each hospital with kits for transporting bacterial isolates and a questionnaire re... | we conducted a prospective , nationwide , population - based study of invasive group a streptococcal infections in israel .
we identified 409 patients ( median age 27 years ; range < 1 - 92 ) , for an annual incidence of 3.7/100,000 ( 11/100,000 in jerusalem ) .
the mortality rate was 5% .
bacteremia occurred in ... |
trabeculectomy has been the surgery of choice in eyes with glaucoma since it was first described by cairns in 1968.1 antifibrotic drugs , such as 5-fluorouracil and mitomycin c ( mmc ) , have been commonly used adjunctively to prevent scar formation , and they have increased the success rate of trabeculectomy . however... | purpose : to compare the effectiveness of standard revision surgery using mitomycin c ( mmc ) with revision using amniotic membrane transplantation and mmc for elevated intraocular pressure ( iop ) after trabeculectomy.patients and methods : a retrospective , nonrandomized comparative study of 36 eyes of 36 patients wi... |
rokowanie w pozaszpitalnym nagym zatrzymaniu krenia ( pnzk ) jest niekorzystne i zaley od licznych zmiennych demograficznych i klinicznych , okolicznoci zdarzenia , odwracalnoci przyczyn oraz jego mechanizmw .
analizie poddano ujednolicone karty wyjazdowe zespow pastwowego ratownictwa medycznego w bielsku- biaej z... | introductionthe prognosis in out - of - hospital sudden cardiac arrest ( ohca ) remains unfavorable and depends on a number of demographic and clinical variables , the reversibility of its causes and its mechanisms.aimto investigate the risk factors of prehospital death in patients with ohca in bielsko county.material ... |
non - nucleoside reverse
transcriptase inhibitors ( nnrtis ) are vital
components of highly active antiretroviral therapy ( haart ) for the
treatment of hiv .
currently , there are five fda - approved nnrtis coadministered
as a combination therapy with nucleoside reverse transcriptase inhibitors
( nrtis ) o... | the
development of novel non - nucleoside inhibitors ( nnrtis ) with
activity against variants of hiv reverse transcriptase ( rt ) is crucial
for overcoming treatment failure .
the nnrtis bind in an allosteric
pocket in rt 10 away from the active site .
earlier
analogues of the catechol diether compound ... |
we performed sequential cross - sectional assessments from a prospective cohort study of andean children in peru ( 3 ) . during 20092011 ,
children <3 years of age from the district of san marcos , cajamarca , peru , were assessed for aris during weekly household visits .
the population was rural and had low income... | we examined nasopharyngeal pneumococcal colonization density patterns surrounding acute respiratory illnesses ( ari ) in young children in peru .
pneumococcal densities were dynamic , gradually increasing leading up to an ari , peaking during the ari , and decreasing after the ari .
rhinovirus co - infection was as... |
recently , user authentication scheme in e - commerce and m - commerce has become one of important security issues .
however , the security weaknesses in the remote user authentication scheme have been exposed seriously due to the careless password management and the sophisticated attack techniques . several schemes ... | recently , many biometrics - based user authentication schemes using smart cards have been proposed to improve the security weaknesses in user authentication system . in 2011 , das proposed an efficient biometric - based remote user authentication scheme using smart cards that can provide strong authentication and mutu... |
patient adherence to prescribed therapies in type 2 diabetes mellitus ( t2 dm ) including lifestyle changes and medications , is of substantial importance . with the large and increasing number of patients affected by t2 dm and the associated disease and economic burden to patients , payers , and employers ,
there is... | backgroundadherence to prescribed diabetes medications is suboptimal , which can lead to poor glycemic control and diabetic complications .
treatment - related weight gain is a side effect of some oral antidiabetic agents and insulin , which may negatively affect adherence to therapy.objectivethis study investigated ... |
covalently cross - linked hydrogels are
applied as cell culture templates , absorbent materials ,
nonfouling coatings , contact lenses , and drug delivery vehicles . owing to high water content , reasonable transport
of small molecules , and robust mechanical properties ,
covalently cross - linked
hydrogels a... | the relationship between polymeric
hydrogel microstructure and
macroscopic properties is of specific interest to the materials science
and polymer science communities for the rational design of materials
for targeted applications .
specifically , research has focused on elucidating
the role of network forma... |
nephrotic - range proteinuria is usually caused by primary or secondary glomerular diseases associated with diabetes , drugs , malignancy , infectious disease , or autoimmune disease .
although proteinuria caused by ras has been reported in some cases , it is uncommon to cause significant heavy proteinuria , . during... | renal artery stenosis ( ras ) is commonly presented with hypertension and chronic kidney disease .
we report a rare case of ras occurring in a 78-year - old man who presented with nephrotic - range proteinuria .
renal biopsy on the left side was performed , and results showed mesangiopathic glomerulonephritis , whi... |
the incidences of various chronic diseases and diseases of aging in industrialized societies are increased by excess energy intake and lack of exercise .
one example is metabolic syndrome , characterized by obesity , insulin resistance , glucose intolerance , dyslipidermia , and hypertension .
numerous studies sugg... | we found that chongkukjang , traditional unsalted fermented soybean , has an antiobesity effect in mice with diet - induced obesity and examined the changes in hepatic transcriptional profiles using cdna microarray .
high - fat diet - induced obese c57bl/6j mice were divided into three groups : normal - diet control ... |
postherpetic neuralgia ( phn ) is the persistence of pain after the disappearance of the rash caused by the herpes zoster virus .
the definition of phn has been controversial , ranging from pain persisting after the healing of rash to pain that continues beyond a period that varies between 1 and 6 months .
risk fa... | postherpetic neuralgia has been variably defined but is generally understood to be pain that persists for longer than a few months after an attack of herpes zoster .
pain persists for years in approximately 10 % of those afflicted with acute herpes zoster .
the likelihood of postherpetic neuralgia increases with o... |
inflammation is associated with disease progression and , by largely unknown mechanisms , has been said to lead to drive oncogenesis . at inflamed sites ,
neutrophils deploy a potent antimicrobial arsenal that includes proteinases , antimicrobial peptides , and ros .
although ross are potently antimicrobial by virt... | inflammation is associated with disease progression and , by largely unknown mechanisms , has been said to drive oncogenesis . at inflamed sites ,
neutrophils deploy a potent antimicrobial arsenal that includes proteinases , antimicrobial peptides , and ros .
reactive oxygen species ( ross ) induce chemokines . in ... |
mirna genes are scattered among each of the chromosomes in humans , except for the y chromosome .
mirnas can be encoded in independent transcription units , in polycistronic clusters , or within the introns of protein - coding genes .
they are primarily derived from capped , polyadenylated rna polymerase ii transcr... | micrornas ( mirnas ) are small non - coding rnas that regulate gene expression at the transcriptional or posttranscriptional level .
many mirnas are found to play a significant role in cancer development either as tumor suppressor genes or as oncogenes .
examination of tumor - specific mirna expression profiles in ... |
the diagnosis of hepatocellular adenomas ( hca ) may occasionally be difficult for the following reasons.the nodule is discovered in a context different to what we are used to see , such as in men , in women not exposed to oral contraceptives ( oc ) , in older persons , or in children.the tumor per se may be difficult ... | in europe and north america , hepatocellular adenomas ( hca ) occur , classically , in middle - aged woman taking oral contraceptives .
twenty percent of women , however , are not exposed to oral contraceptives ; hca can more rarely occur in men , children , and women over 65 years .
hca have been observed in many ... |
in recent years the existence of multiple stable states , bifurcations and thresholds in ecological systems has been a focus for ecologists , with examples in a variety of aquatic , marine and terrestrial systems ( scheffer et al . ,
these empirical observations have been supported by conceptual and numerical models ... | multiple stable states , bifurcations and thresholds are fashionable concepts in the ecological literature , a recognition that complex ecosystems may at times exhibit the interesting dynamic behaviours predicted by relatively simple biomathematical models .
recently , several papers in global ecology and biogeograph... |
lung cancer is the fourth most common cancer and the leading cause of cancer deaths in korea .the platinum - based regimen using paclitaxel , gemcitabine and docetaxel has shown high response rates and a survival benefit for patients with advanced non - small cell lung cancer ( nsclc ) .
no significant difference in ... | purposethis phase ii clinical trial was conducted to evaluate the activity and safety of a combination treatment of paclitaxel ( genexol ) plus carboplatin in patients with advanced non - small cell lung cancer.materials and methodschemotherapy - nave patients having histologically confirmed advanced or metastatic non ... |
a 54-year - old man was admitted to the hematology department , robert - bosch - hospital , stuttgart , germany , in early 2010 , with fever ( 39.5c ) , chills , and minor dyspnea that had lasted for 3 days .
four years earlier , he had received a stem cell transplant for acute myeloid leukemia , which was in first c... | we describe a case of human tularemia caused by francisella tularensis subsp .
holarctica in a stem cell transplant recipient with chronic graft - versus - host disease who was receiving levofloxacin prophylaxis .
the infection was characterized by pneumonia with septic complications .
the patient was successfull... |
holt oram syndrome ( hos ) is a rare autosomal dominant disorder involving the hands , arms , and the heart anomalies .
congenital cardiac and upper limb malformations often occur together and categorized as heart - hand syndromes .
the most common of them is the hos , which characterized by septal defects of the ... | holt oram syndrome ( hos ) is a rare autosomal dominant disorder , characterized by upper limb dysplasia and congenital cardiac defect .
we report two cases with hos , first associated with renal agenesis , coronal hypospadias , urethral duplication and second associated with duodenal atresia and horseshoe kidney th... |
the lifetime risk of a man developing histologically confirmed benign prostate hyperplasia ( bph ) has been reported to be 50% in those in the 51 - 60 years age group and increasing to 70% in the 61 - 70 years age group . with the exclusion of non - melanomatous skin malignancy , prostate cancer ( pca )
the internati... | introduction : with the exclusion of non - melanomatous skin malignancy , prostate cancer ( pca ) is the second most prevalent cancer in men globally . it has been reported that the majority of men will develop benign prostatic hyperplasia ( bph ) by the time they reach their 60s .
together , these prostatic diseases... |
australia recorded its first case of swine origin influenza a ( h1n1 ) virus infection on 7 may 2009 in a traveller returned from the united states ( us ) but by 27 may had recorded 61 confirmed cases . at the same time the world health organization ( who ) had documented almost 13 000 confirmed cases in 46 countries ... | background the populationbased impact of infection with swine origin influenza a ( h1n1 ) virus infection was not clear in the early days of the epidemic towards the end of may 2009 .
australia had seven confirmed cases by 22 may 2009 .
we aimed to compare available data on swine origin influenza a ( h1n1 ) virus... |
coenzyme q10 , also known as ubiquinone , is a lipophilic component of all cellular membranes and has multiple metabolic functions . in the mitochondrial electron - transport chain , it transfers electrons from complex i ( nadh dehydrogenase - ubiquinone oxidoreductase ) and complex ii ( succinate dehydrogenase ) to co... | coenzyme q10 ( coq10 ) or ubiquinone is one of the two electron carriers in the mitochondrial respiratory chain which has an essential role in the process of oxidative phosphorylation .
defects in coq10 synthesis are usually associated with the impaired function of coq10dependent complexes i , ii and iii .
the rece... |
a crucial part of any evaluation for the primary angle closure ( pac ) spectrum of diseases is an examination of anterior chamber angle ( aca ) anatomy .
gonioscopy is the current clinical gold standard for evaluating aca anatomy , allowing assessment of the angle over 360 degrees as well as identification of other a... | purpose . to evaluate interobserver , intervisit , and interinstrument agreements for gonioscopy and fourier domain anterior segment optical coherence tomography ( fd asoct ) for classifying open and narrow angle eyes
. methods .
eighty - six eyes with open or narrow anterior chamber angles were included .
the su... |
key clinical messageibrutinib is a firstinclass inhibitor of bruton 's tyrosine kinase , which is approved for use in chronic lymphocytic leukemia , mantle cell lymphoma , and waldenstrom 's macroglobulinemia .
although ibrutinib has been linked to an increased incidence of atrial fibrillation , this is the first rep... | |
. however , restenosis following angioplasty occurring in up to 50% of patients limits the long - term effectiveness of this treatment .
early studies to elucidate the mechanisms of restenosis focused on intimal de - endothelialization as a primary cause , while more recent studies indicated a potential role for adve... | background : accumulating evidence indicates a potential role of adventitial vasa vasorum ( vv ) dysfunction in the pathophysiology of restenosis
. however , characterization of vv vascularization in restenotic arteries with primary lesions is still missing . in this study
, we quantitatively evaluated the response... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.