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the joint national committee ( jnc ) 7 defined resistant hypertension as failure to achieve goal blood pressure ( bp ) ( < 140/90 mm hg for the overall population and < 130/80 mm hg for those with diabetes mellitus or chronic kidney disease ) in a patient who adheres to maximum tolerated doses of 3 antihypertensi... | resistant hypertension is a failure to achieve goal bp ( < 140/90 mm hg for the overall population and <
130/80 mm hg for those with diabetes mellitus or chronic kidney disease ) in a patient who adheres to maximum tolerated doses of 3 antihypertensive drugs including a diuretic .
the kidneys play a critical ro... |
kidney diseases including chronic kidney disease ( ckd ) and acute kidney injury ( aki ) are rapidly increasing worldwide . nowadays
the incidence of aki varies from 140 to 620 per million people based on different reports and is becoming a global concern [ 2 , 3 ] .
recently , although the understanding on ckd and... | cox-2/mpges-1/pge2 cascade plays critical roles in modulating many physiological and pathological actions in different organs . in the kidney ,
this cascade is of high importance in regulating fluid metabolism , blood pressure , and renal hemodynamics . under some disease conditions , this cascade displays various ac... |
despite recent advances in endovascular techniques and technology for coil embolization of intracranial aneurysms , thromboembolic complications intra- and post - procedure are not uncommon , particularly in branches originating from the dome of the aneurysm .
surgeons often face the dilemma of achieving complete coi... | abstractendovascular coil embolization of arterial aneurysms is often complicated by reduced blood flow to branching arteries . to determine the optimal coil configuration for safe embolization of endovascular aneurysms without compromising blood flow in branching arteries .
a 3-dimensional voxel model , built based ... |
there has been little research into how human immunodeficiency virus ( hiv ) infection and the aging process together influence the health and well being of infected individuals , which poses many challenges for health care providers , as well as for policy makers.1 given the advent of highly active antiretroviral ther... | highly active antiretroviral therapy ( haart ) has had a profound impact on improving the long - term prognosis for individuals infected with human immunodeficiency virus ( hiv ) .
haart has been available for close to two decades , and now a significant number of patients with access to haart are over the age of 50 ... |
costa rica , with a total land area of 51,100 square kilometers , is a country slightly smaller than the state of west virginia and has a total population of 4.02 million ( 1 ) .
the indigenous population , residing on twenty - two indigenous reserves , comprises only 1.7% of this population .
there are currently s... | this study surveyed the dental health of three costa rican indigenous populations and two rural , non - indigenous communities .
sixty - six individuals , both children and adults , were interviewed regarding dental hygiene practices and the dentition of eighty - eight children from the ages of two to thirteen was ex... |
posttraumatic stress disorder ( ptsd ) is a psychiatric condition that develops after exposure to a trauma in the form of a threatened or actual harm , death , or sexual violence .
the first describes intrusion symptoms , such as nightmares , flashbacks , and unwanted memories of the traumatic event .
the second is... | clonidine and guanfacine are alpha-2 receptor agonists that decrease sympathetic outflow from the central nervous system .
posttraumatic stress disorder ( ptsd ) is an anxiety disorder that is theorized to be related to a hyperactive sympathetic nervous system .
currently , the only us food and drug administration ... |
positron emission tomography ( pet ) is
a powerful quantitative
tool for in vivo imaging compounds
labeled with positron emitting radioisotopes
that trace biological processes in the body .
however , in many occasions , the
biological parameters on the image
voxel level as determined by conventional
sta... | parametric images generated from dynamic positron emission tomography ( pet )
studies are useful for presenting functional / biological information in the
3-dimensional space , but usually suffer from their high sensitivity to image noise .
to improve the quality of these images , we proposed in this study a modi... |
staphylococcus aureus is known as one of the most important human pathogens frequently implicated in nosocomial infections .
s. aureus has the ability to grow in different environmental conditions and as a part of the normal human flora , it can colonize areas such as the anterior nares , perineum , armpit , and groi... | background : staphylococcus aureus is known as a powerful pathogen that causes various infections .
emergence of methicillin - resistant s. aureus ( msra ) is responsible for nosocomial and community - acquired infections worldwide.aims:the present study aimed to evaluate the performance and ability of eight differen... |
patients with intestinal failure ( if ) usually require home parenteral nutrition ( hpn).13 although lifesaving , hpn carries an increased risk of complications , including catheter sepsis , venous thromboembolic disease and if - associated liver disease ( ifald).3
4 the risk of liver pathology in if is well recognis... | patients with intestinal failure ( if ) and home parenteral nutrition commonly develop abnormal liver function tests .
the presentations of if - associated liver disease ( ifald ) range from mild cholestasis or steatosis to cirrhosis and decompensated liver disease .
we describe the reversal of ifald in an adult pa... |
since the publication of the landmark report to err is human by the institute of medicine in 2000 , studies of errors in medical practice had been increasingly performed .
there is no doubt that ensuring patients ' safety is a clinician 's most fundamental responsibility . to prevent errors from occurring ,
it is... | purpose . to arouse ophthalmologists ' awareness in patient safety by reviewing sentinel events in ophthalmology submitted to a web - based incident reporting system involving all public hospitals in hong kong
. methods .
sentinel events in ophthalmology reported from november 2007 to october 2014 were identified a... |
congenital posterolateral diaphragmatic hernia ( cdh ) or bochdalek hernia ( bh ) is a life - threatening malformation characterized by an anomaly of the posterolateral foramina of bochdalek , through which the abdominal viscera migrate into the chest during fetal development.1 the incidence of cdh is 1 in 2,500 to 3,0... | we present a novel case of the association of right - sided bochdalek hernia , a diaphragmatic life - threatening malformation , and kartagener syndrome , which is characterized by congenital bronchiectasis , chronic sinusitis , and situs inversus .
the developmental and clinical findings are discussed .
when an as... |
biomarkers of airway inflammation and oxidative stress can be measured noninvasively using exhaled breath condensate ( ebc ) sampling of airway lining fluid .
leukotriene b4 ( ltb4 ) , a potent neutrophil chemoattractant , and 8-isoprostane , which is formed during oxidative stress conditions by free - radical peroxi... | the reproducibility of exhaled breath condensate ( ebc ) mediators is not well documented in chronic obstructive pulmonary disease ( copd ) .
this study assessed within assay ( wa ) , within ( wd ) and between day ( bd ) reproducibility of ebc leukotriene b4 ( ltb4 ) and 8-isoprostane .
three ebc samples were colle... |
in 2010 , young adults aged 1825 reported the highest prevalence of current use of a tobacco product ( 40.8% ) compared to youth ( ages 1217 ) or adults ( ages 26 and older ) .
although young adult ( aged 1824 ) cigarette smoking prevalence decreased overall ( 24.4% to 20.1% ) from 2005 through 2010 , the highest pre... | few studies address the developmental transition from youth tobacco use uptake to regular adulthood use , especially for noncigarette tobacco products .
the current study uses online panel data from the legacy young adult cohort study to describe the prevalence of cigarette , other tobacco product , and dual use in a... |
the international classification of headache disorders recognizes three subsets of low volume headache , one of them being spontaneous intracranial hypotension ( sih ) .
sih has been attributed to a breach of dural diverticulae or tearing of nerve root sheaths
. there may be a clear trigger or at times it may occur... | spontaneous intracranial hypotension ( sih ) is a cause of new persistent headache , which disappears on recumbence and reappears in sitting / standing position ( orthostatic headache ) .
we present a case of orthostatic headache , where the patient was suspected to have sih and was subjected to radionuclide cisterno... |
postoperative endophthalmitis following cataract surgery could have potentially devastating consequences of severe vision loss or even blindness .
the average time from surgery to presentation of endophthalmitis is usually 6 - 7 days .
this is a rare cause of endophthalmitis in the postoperative setting following c... | a 53-year - old caucasian man underwent femtosecond cataract surgery and then presented with pain and hand motions vision 1 day following surgery .
anterior segment examination showed a 2-mm - layered hypopyon , a well - centered intraocular lens in the sulcus , and an obscured view to the fundus .
b - scan ultraso... |
construction workers are engaged in a wide range of activities and often become victims of different occupational diseases and injuries .
road construction workers include asphalt workers , ground preparation workers , and heavy vehicle operators who are directly or indirectly exposed to occupational hazards such as ... | objective : the study focused on assessment of the health status of workers during construction phase of highway rehabilitation projects at six selected sites of n5 around lahore , including kala shah kaku , muridke , kamuki , bhaipheru , pattoki , and okara.methods : the study was based on multi - methods approach inv... |
upper extremity 's ( ue ) motor coordination , manual dexterity , muscle strength and sensibility are essential for adequate performance of manual tasks ( 1 ) .
manual asymmetry refers to the tendency to favor one hand for performance of skilled manual tasks , and is important in every sensory and motor function ( 2 ... | this study was done to evaluate differences in pressure pain threshold , grip strength , manual dexterity and touch pressure threshold in the dominant and non - dominant hands of right- and left - handed subjects , and to compare findings within and between these groups .
thirty - nine right - handed and twenty - one... |
nodal involvement is the most important prognostic factor in determining survival for patients with non - small cell lung cancer ( nsclc ) ( 1 , 2 ) .
however , conventional lymph node ( ln ) staging does not effectively reflect the wide differences in ln involvement and patient survival , even in patients classified... | mediastinal ( n2 ) lymph node involvement is heterogenous with huge variation in the extent and grouped together under stage iiia .
however , they showed a different survival even in the same stage .
we tried to determine the prognostic implication of the multiple station n2 lymph node metastasis in stage iiia n2 n... |
brown - sequard syndrome ( bss ) was first described in 1840 by charles - douard brown - sequard through experiments of spinal cord hemi - section in animal models.1 ) bss is a rare condition as an incomplete spinal cord injury ( sci ) that is caused by traumatic events , such as , most commonly , stab wounds , followe... | we report a case of brown - sequard syndrome ( bss ) caused by an accidental stab injury of the cervical spine that shows clear magnetic resonance imaging ( mri ) findings and clinical presentation .
a 42-year - old woman was brought into the emergency department after a stab injury on the right side of the posterior... |
it uses a pencil x - ray beam that 's detected after passing through the patient .
both the x - ray source and detector traverse the scanning area with a rectilinear motion .
, dpx series , lunar md 7164 , wi , with a scan speed of 1 mm / s and a resolution of 0.5 0.5 mm ) has a highly stable potential x - ray gen... | objectivethe purpose of this study is to estimate a patient 's organ dose ( effective dose ) during performance of dual x - ray absorptiometry by using the correlations derived from the surface dose and the depth doses in an anthropomorphic phantom.materials and methodsan anthropomorphic phantom was designed and tlds (... |
alpha - synuclein is associated with both familial and idiopathic cases of parkinson 's disease.the precise function of alpha - synuclein remains equivocal.alpha-synuclein misfolds and forms protein aggregates in parkinson 's disease and in various in vitro and in vivo models of synucleinopathies.alpha-synuclein has be... | the aggregation , deposition , and dysfunction of alpha - synuclein ( asyn ) are common events in neurodegenerative disorders known as synucleinopathies .
these include parkinson 's disease , dementia with lewy bodies , and multiple system atrophy .
a growing body of knowledge on the biology of asyn is emerging and... |
orthogonal frequency division multiplexing ( ofdm ) is multicarrier modulation which provides reliable high speed data rate because of its high spectral efficiency and its robustness against multipath fading channel .
one of the significant problems of the ofdm signal is its high peak - to - average power ratio ( pap... | time domain cyclic - selective mapping ( tdc - slm ) reduces the peak - to - average power ratio ( papr ) in ofdm systems while the amounts of cyclic shifts are required to recover the transmitted signal in a receiver .
one of the critical issues of the slm scheme is sending the side information ( si ) which reduces ... |
silent myocardial infarction ( mi ) is common , and may account for 2060% of all mi in otherwise asymptomatic patients over the age of 45 [ 14 ] .
the diagnosis of unrecognized infarction has traditionally been defined as the presence of pathologic q waves on the electrocardiogram ( ecg ) of a patient without a clin... | unrecognized myocardial infarction ( mi ) carries a poor prognosis in the general population , but its prognostic value is less clear in high - risk patients .
we sought to determine whether q waves on electrocardiogram ( ecg ) , suggestive of unrecognized mi , predict cardiovascular events in patients with stable co... |
treatment of infrabony defects with different grafting materials has provided a reliable method of achieving defect fill .
recent studies indicate , however that regrowth of osseous tissue alone does not necessarily lead to periodontal regeneration .
in fact , the most common healing pattern following the graft pro... | background : doxycycline has been advocated as useful adjuncts in periodontal therapy not only due to their antimicrobial actions , but also to their recently recognized anti - collagenolytic , anti - inflammatory , osteoclast inhibitory and fibroblast stimulating property .
the purpose of the present cohort study wa... |
fabry disease ( fd ) is a rare x - linked inherited condition which , due to the absence or reduction of -galactosidase a ( gla ) activity in lysosomes , results in an accumulation of globotriaosylceramide ( gb3 ) in endothelial cells , smooth muscle cells , peripheral nerves and in other tissues .
patients experienc... | backgroundfabry disease ( fd ) is an x - linked inherited disease based on the absence or reduction of lysosomal - galactosidase ( gla ) activity .
the enzymatic defect results in progressive impairment of cerebrovascular , renal and cardiac function . normally , female heterozygote mutation carriers are less strongl... |
the authors would like to thank the institute for pathology of the leipzig university , chairman prof .
the authors would also like to thank the department of radiology of the leipzig university , prof .
the authors would like to thank the institute for pathology of the leipzig university , chairman prof .
... | introduction : the desmoid fibromatosis is a very rare connective tissue disease which is recognized as semimalignant . the aim of this work is to review the relevant literature and to analyze the management of our patient collective .
material and method : surgery was performed on 7 patients with extraabdominal desm... |
ten paid undergraduate students ( mean age 21 2 years ( sd ) ) participated in the experiment .
three subjects were left - handed according to coren s test coren ( 1993 ) , and all others were right - handed . they were treated in accordance with the local guidelines and signed an informed consent form .
they w... |
subitizing refers to fast and error - free numerosity judgment for small ( < 4 ) sets of items . for larger sets , the slower process of
counting is used .
counting has a serial character , whereas subitizing is believed to have a parallel character .
while subitizing was initially found in vision , it has bee... |
archives preserve documents written on papyrus , parchment papers , papers , and electronic supports .
these organic , inorganic , and synthetic materials are deteriorated by physical , chemical , and biological agents . as environmental microorganisms can deteriorate the different supports of heritage significance... | documentary heritage is permanently subject to suffering from physical , chemical , and/or biological alterations .
biological deterioration by microorganisms ( bacteria and fungi ) causes undesirable changes on material properties .
microorganisms affect different organic , natural or synthetic substrates ( cellul... |
the present study reveals 12-month clinical outcomes for 13,133 patients with acute myocardial infarction ( ami ) who were enrolled in the nationwide prospective korea acute myocardial infarction registry ( kamir ) between november 2005 and december 2007 .
launched in november 2005 , the kamir is the first nationwide... | in korea , the incidence of acute myocardial infarction has been increasing rapidly .
twelve - month clinical outcomes for 13,133 patients with acute myocardial infarction enrolled in the nationwide prospective korea acute myocardial infarction registry study were analyzed according to the presence or absence of st -... |
the syndrome of idiopathic granulomatous hepatitis as a cause of fever of unknown origin is now well established but only a few follow - up reports have established the clinical outcome .
idiopathic granulomatous hepatitis is a rare disease of unknown cause that is characterized by recurrent fevers and granuloma in t... | idiopathic granulomatous hepatitis is a rare disease of unknown cause that is characterized by recurrent fevers and granuloma in the liver .
attempts to define an exact etiology of the fever of granulomatous hepatitis frequently do not yield a precise diagnosis .
idiopathic granulomatous hepatitis was confirmed aft... |
several studies show that a diet rich in fruits and vegetables has inverse effects on the occurrence of chronic disorders .
antioxidants in fruits and vegetables may help to protect people from chronic disorders such as ischemic heart disease .
-carotene , tocopherol , and vitamin c by inhibiting low - density lipo... | background : the food frequency questionnaire ( ffq ) , as a way to assess the dietary intake in comparison with other methods , is easier to analyze and takes less time and is less costly . our aim in this study was to develop and validate an ffq for estimating the intakes of selected antioxidants in elderly iranian p... |
perfusion , permeability and magnetic resonance spectroscopy ( mrs ) are now widely used in the research and clinical settings . in the clinical setting ,
qualitative , semi - quantitative and quantitative approaches such as review of color - coded maps to region of interest ( roi ) analysis and analysis of signal in... | abstractperfusion , permeability and magnetic resonance spectroscopy ( mrs ) are now widely used in the research and clinical settings . in the clinical setting ,
qualitative , semi - quantitative and quantitative approaches such as review of color - coded maps to region of interest analysis and analysis of signal in... |
origin and identification of sandflies - the turkmen sahara
villages in northeastern iran are a focus of zcl , where l. major
parasites are the major causative agent of zcl .
two sister
paraphlebotomus species were collected regularly from 18
villages of gonbad kavous and maraveh tapeh in late june and the mi... | individual , naturally occurring phlebotomus
mongolensis and phlebotomus caucasicus from iran
were screened for infections with the maternally inherited intracellular
rickettsia - like bacterium wolbachia
pipientis via targeting a major surface protein gene ( wsp ) .
the
main objective of this study was to ... |
endemic highly pathogenic avian influenza virus ( aiv ) h5n1 in poultry has been present since the first occurrence in 1997 in hong kong .
aiv h5n1 circulates in waterfowl and domesticated avian species and has evolved into multiple phylogenetically distinct genotypes and clades [ 13 ] , with geographically distinct ... | secretory immunoglobulin a ( siga ) acts as the first line of defense against respiratory pathogens . in this assay
, the variable regions of heavy chain ( vh ) and light chain ( vl ) genes from a mouse monoclonal antibody against h5n1 were cloned and fused with human iga constant regions . the full - length chimeric... |
androgenetic alopecia ( aga ) is a common condition characterized by reduced density of scalp hair with a receding hairline in males occurring due to androgen - mediated conversion of susceptible terminal hair into vellus hair and is largely determined by genetic factors and the peripheral action of androgens .
the e... | introduction : androgenetic alopecia ( aga ) is characterized by miniaturization of the hair follicle , leading to vellus transformation of the terminal hair follicle .
it is caused by interactions between androgens , several genes , and environmental factors with hair follicles .
benign prostatic hyperplasia ( bph... |
this subset analysis is based on the conrad study , which was designed to compare palliative crt versus palliative chemotherapy alone to poor - prognosis patients with unresectable locally advanced nsclc stage iii .
the primary endpoint was os , and the secondary endpoints were hrqol , ttp , and toxicity .
included... | introduction : poor prognosis patients with bulky stage iii locally advanced non small - cell lung cancer may not be offered concurrent chemoradiotherapy ( crt ) . following a phase iii trial concerning the effect of palliative crt in inoperable poor prognosis patients ,
this analysis was performed to explore how tu... |
palliative chemotherapy is the main treatment option for patients with metastatic esophageal cancer and good eastern cooperative oncology group performance status ( ecog ps ) . during the last decade ,
several chemotherapeutic agents [ e.g. , cisplatin , 5-fluorouracil ( 5-fu ) , mitomycin c , irinotecan , vinorelbin... | undifferentiated large cell carcinoma is a rare entity in esophageal cancer and very few data are available in the literature on this uncommon histological subtype .
we report a case of a 58-year - old caucasian male previously treated with cisplatin/5-fluorouracil , docetaxel and carboplatin / plitidepsin who receiv... |
kawasaki disease ( kd ) is a self - limiting systemic inflammatory disease of childhood,1 ) and the most important issue with this condition is coronary artery complications .
the prevalence of coronary artery involvement is approximately 15 - 25% , but it decreases to 5% after the introduction of intravenous immunog... | acute giant coronary aneurysm after kawasaki disease ( kd ) is a catastrophic complication that can be fatal and very difficult to manage .
however , no fixed consensus has been reached for the management of super - giant coronary aneurysms in the acute setting . here ,
we report the successful management of young ... |
chemical inducers of dimerization ( cids ) are cell - permeable small molecules capable of dimerizing two protein targets .
the most widely used cid , the natural product rapamycin and its relatives , is immunosuppressive due to interactions with endogenous targets and thus has limited utility in vivo . here
we rep... | |
melanocytoma presents as a deeply pigmented tumor and rarely arises in the iris or ciliary body of the eye .
it usually appears as a focal tumor , slowly enlarging and invading the anterior chamber angle , and may develop secondary glaucoma [ 1 , 2 ] . the mechanism of the intraocular pressure elevation has not yet b... | we report a rare case with histologically proven melanocytoma of the iris that demonstrated diffuse melanocytic proliferation with uncontrolled secondary glaucoma and investigate the etiology of the intraocular pressure elevation .
the patient was a 78-year - old man with a history of darkened iris of his left eye . ... |
duplicate ( or redundant ) publication can be defined as " publication of a paper that overlaps substantially with one already published in print or electronic media " ( 1 ) . the practice of duplicate publications is considered unethical because it both artificially exaggerates the findings or ideas and wastes the tim... | duplicate publication is considered unethical .
it has several negative impacts . to estimate the frequency and characteristics of duplicate publications in korean medical journals
, we reviewed some portion of korean journal articles . among 9,030 articles that are original articles indexed in koreamed from januar... |
malignant neoplasms of the paranasal sinuses and nasal cavity are rare , comprising only 3% of all head and neck malignancies .
this includes both primary sinonasal neoplasms like squamous cell carcinoma , nasopharyngeal carcinoma , lymphoma , esthesioneuroblastoma , primary sinonasal melanoma and adenocarcinoma of m... | we describe a case of a 53-year - old man presented to our ent opd with chief complaints of recurrent right supraorbital swelling for last 6 months , which was associated with bilateral periorbital edema .
contrast - enhanced computerized tomographic scan showed a large frontoethmoidal mucocele with expansion of the ... |
a 33-year - old south indian male presented with complaints of pain in the left eye ( le ) with painful eye movements since 25 days and gradual progressive worsening of vision in his le since 20 days .
there was no history of fever , chronic cough , evening rise of temperature , lymphadenopathy , contact with tb , tr... | we report a case of ocular tuberculosis ( tb ) which initially presented with disc edema and was mistaken for optic neuritis . with no definite pathology being identified , the patient was treated on the lines of optic neuritis with intravenous ( iv ) steroid with beneficial effect .
ocular tb was suspected when he p... |
the 95 ankles from 57 patients with achilles tendon tightness were included in the study .
the first group ( idiopathic ) consists of the patients with no other specific disorders ( n = 26 ) or with disorders not involving the muscle and the tendon , such as flat foot ( n = 13 ) and tibial or femoral torsion ( n = 4 ... | backgroundthe risk of various complications after achilles tendon lengthening is mainly related to the length of surgical exposure and the lengthening method .
a comprehensive technique to minimize the complications is required.methodsthe treatment of achilles tendon tightness in 57 patients ( 95 ankles ) were perfor... |
cryptococcosis is an opportunistic fungal infection caused by cryptococcus species , and cryptococcus neoformans is considered to be a major primary pathogen .
although exposure to cryptococcus species is common , the development of symptomatic disease usually requires immunosuppression . with an increasing number of... | we herein report the case of a 63-year - old man who presented with a 3-month history of a cutaneous nodular lesion of his jaw , low grade fever , lethargy and progressive cognitive impairment .
he had a 30-year history of multiple sclerosis and had been treated with fingolimod for the previous 2 years .
laboratory... |
molecular / theoretical modeling studies have revealed that thyroid hormones and toxic chlorinated aromatic hydrocarbons of environmental significance ( for which dioxin or tcdd is the prototype ) have similar structural properties that could be important in molecular recognition in biochemical systems .
these molecu... | |
the disease is named after victor babes , the hungarian pathologist and microbiologist who identified intraerythrocytic microorganisms as a cause of febrile hemoglobinuria in cattle in 1888 . then in 1893
, theobald smith and frederick l. killborne identified a tick as a vector for transmission of babesia bigemina in... | this article describes the case of spontaneous splenic rupture as a rare complication of infection with babesia species .
we will discuss the symptomatology that this disease could present along with both surgical and non - surgical management approaches .
babesia infection often presents with mild to moderate symp... |
thus , there must be excellent candidates for the rapid and inexpensive diagnosis of cvd .
c - reactive protein ( crp ) is the most widely used as a cvd marker for the early diagnosis of the disease .
recently , the usual way to predict cvd is detecting the concentration of crp in serum .
the most common approach... | a novel horseradish peroxidase- ( hpr- ) doped magnetic core - shell fe3o4@sio2@au nanocomposites ( fe - au mnps ) were employed on immunoassay for the determination of c - reactive protein ( crp ) based on a electrochemical quartz crystal microbalance detector ( eqcm ) .
firstly , the secondary crp antibody and hrp ... |
hepatocellular carcinoma ( hcc ) is one of the most common neoplasms in the world .
multidetector row computed tomography ( mdct ) has been proven to be useful in displaying the relationship between the tumor and the hepatic blood vessels , which is greatly helps guiding surgery . during the mdct procedure ,
multip... | backgroundthe aim of this study was to investigate the feasibility of a split - bolus combined phase contrast - enhanced computed tomography protocol in evaluation of liver vasculature in hepatocellular carcinoma ( hcc ) patients for the purpose of surgery guidance.material/methodstwo groups of patients were recruited ... |
some persons have ideas of suicide that they will never act on ; some plan for days , weeks , or even years before acting and others take their lives seemingly on impulse without premeditation .
many of those attempt suicide by intention , that is , they want to die strongly .
subsequently , after the suicidal atte... | objective : some persons attempt suicide with a strong intention to die and some are not .
presently , no distinctive grouping has been done on the basis of the suicidal intention , though there is a significant variation in the psycho - socio - demographic profile , suicidal ideation , and intent within the persons ... |
kidney injuries following blunt abdominal trauma in humans are described in 310% of cases [ 1 , 2 ] .
the most common cause of blunt renal trauma is the mechanism of rapid kidney deceleration , which occurs in motor vehicle accidents , falls from height , or on a direct impact in the lumbar area .
these may result ... | this study presents a case of avulsion of the left renal artery from the aorta and splenic rupture after blunt abdominal trauma accompanied by an extensive crush syndrome .
based on contrast enhanced abdominal ultrasound and computed tomography ct , the patient was qualified for urgent surgical intervention with rem... |
rosai dorfman disease is a benign histiocytic proliferation that can present with large lymph node masses , most often cervical .
the extranodal disease occurs in about 43% and it usually includes skin , soft tissues , respiratory system , genitourinary system , bones , central nervous system ( cns ) , orbit , thyro... | sinus histicytosis ( rosai dorfman disease ) is a rare , benign granulomatous disease that typically presents with massive cervical lymphadenopathy .
extranodal involvement along with concomitant nodal disease occurs in about 43% of cases .
we present a unique case of a 30-year - old male with cervical , retroperi... |
a 71-year - old man with a high alcohol consumption was transferred to our hospital due to altered consciousness .
he was admitted to the referring medical center twice , in april 2003 and january 2004 , because of altered mental state and unsteady gait . at that time
a neurologic examination showed astasia , pares... | we report unusual mri findings ( including those from diffusion - weighted imaging ( dwi ) ) in a patient with recurrent wernicke 's encephalopathy with a remarkable cerebellar lesion .
dwi showed high signal intensities in the superior portion of the cerebellar hemisphere and vermis area .
after thiamine administr... |
cefoperazone is a third - generation cephalosporin antibiotic effective in treating pseudomonas aeruginosa infections , which are otherwise resistant to other antibiotics .
although the drug is mainly excreted in the bile , urinary excretion primarily by glomerular filtration accounts for up to 30% of a dose unchange... | the electroreduction behaviour and determination of cefoperazone using a hanging mercury drop electrode were investigated .
cyclic voltammograms of cefoperazone recorded in universal britton - robinson buffers ph 36 exhibited a single irreversible cathodic peak .
the process was adsorption - controlled .
britton ... |
atrial fibrillation ( af ) is the most common cardiac arrhythmia , which in 2010 was estimated to affect about 33.5 million individuals in the world , with a prevalence around 2.33.4% among adults , and may reach 9% in those aged over 80 years .
studies point to an increase in both incidence and prevalence [ 1 , 4 , ... | atrial fibrillation ( af ) is the most common arrhythmia and is responsible for significant disease burden worldwide .
current evidence has suggested that systemic inflammatory response plays a crucial role in the initiation , maintenance , and progression of af .
so , recent efforts have been directed in search of... |
the acid - etch technique creates a strong bond between the direct bonding materials and enamel , but debonding of the brackets and improper finishing and polishing at the end of treatment have the potential to cause iatrogenic enamel damage4 , excessive plaque accumulation , gingival irritation and increased surface s... | objective : the aim of this study was to evaluate ( 1 ) the effectiveness of one - step polishers on the surface morphology of enamel using scanning electron microscope ( sem ) and compare their effects with conventional systems for residual adhesive removal ; and ( 2 ) the time spent to remove resin remnants.material ... |
medicare in essence is the largest health care insurance provider in the u.s . and the largest government - funded medical entitlement program .
our cohort was restricted to those individuals enrolled in medicare parts a and b fee - for - service with diabetes in 2006 , 2007 , or 2008 .
a beneficiary was included i... | objectivelower - extremity amputation ( lea ) is common among persons with diabetes . the goal of this study was to identify geographic variation and the influence of location on the incidence of lea among u.s .
medicare beneficiaries with diabetes.research design and methodswe conducted a cohort study of beneficiari... |
randomised controlled trials ( rcts ) in attention deficit hyperactivity disorder ( adhd ) have shown that long - acting methylphenidate ( mph ) preparations have similar efficacy to multiple doses of short - acting , immediate - release ( ir ) formulations , but with the advantage of convenient once - daily dosing [ 4... | patients with adhd may have better adherence to treatment with modified - release methylphenidate ( mph - mr ) formulations , which are taken once daily , compared with immediate - release ( ir ) formulations , which need to be taken several times a day .
data on long - term outcomes such as adherence may be lacking ... |
in 1974 sir james paget described the clinical entity , now known as paget 's disease as an eczematous change in the nipple preceding an underlying mammary carcinoma. paget 's disease accounts for 14% of all breast malignancy , the most of them are associated with underlying invasive breast cancer .
we present the ca... | male breast cancer accounts for 1% of all breast malignancies and 0.1% of all male cancer death .
like paget 's disease , dcis is a rare form of male breast malignancy .
we report a 69-year - male presenting with 3 years history of subtle of nipple symptoms and normal breast imaging .
punch biopsy of nipple estab... |
it is an indubitable fact that financing is a core necessity for sustainable health care delivery .
the world health organization maintains that health financing is fundamental to the ability of health systems to maintain and improve human welfare . despite this , financial inclusion with regards to healthcare
desc... | health financing is a core necessity for sustainable healthcare delivery .
access inequalities due to financial restrictions in low - middle income countries , and in africa especially , significantly affect disease rates and health statistics in these regions .
this paper focuses on the role of a national health i... |
these couples should receive preconception counseling on all factors that are discussed during preconception counseling for patients without fertility problems .
additional counseling should address success rates and possible risks from the specific fertility treatments being considered because of the couple s diagno... | couples with fertility problems seeking treatment with assisted reproductive technologies ( art ) such as in vitro fertilization should receive preconception counseling on all factors that are provided when counseling patients without fertility problems .
additional counseling should address success rates and possibl... |
lactic acidosis ( la ) is defined as a state of decreased systemic ph ( ph < 7.35 ) and an elevated plasma lactate concentration ( > 5 mmol / l ) .
typically , la is divided into disorders associated with tissue hypoxia ( cohen and woods classification type a ) and disorders in which tissue hypoxia is absent ( type ... | abstractaims : the principal objective of this study was to retrospectively review a series of cases of lactic acidosis ( la ) in patients with type 2 diabetes mellitus ( t2 dm ) and examine the relationship with the use of metformin .
more generally , the study enabled an investigation of the profiles of patients di... |
we have investigated photochemical reactions of dab with qds at ensemble and single - molecule levels by recording and analyzing pl spectra of qd solutions and pl intensity trajectories of single qds both in the presence of dab and under high - intensity photoactivation .
1a shows the effect of concentration of dab o... | photoinduced electron transfer in donor - acceptor systems composed of quantum dots ( qds ) and electron donors or acceptors is a subject of considerable recent research interest due to the potential applications of such systems in both solar energy harvesting and degradation of organic pollutants .
herein , we emplo... |
the hunt study consists of three surveys in 19842008 where the entire population of the norwegian county of nord - trndelag was invited to participate . in 19951997 , 66,140 men and women ( 71.2% ) , aged 20 years or older , participated in the second of these surveys ( hunt2 ) , consisting of questionnaires , physical... | objectiveknowledge on mortality in autoimmune diabetes with adult onset is limited .
we compared mortality in adult - onset autoimmune diabetes and type 2 diabetes , taking into account metabolic risk factors , hba1c , lifestyle , and socioeconomic factors.research design and methodsparticipants of the population - b... |
mccune - albright syndrome ( mas ) is a rare and sporadic disease characterized by a triad of poly / monostotic fibrous dysplasia , caf - au - lait macules and hyperfunctioning endocrinopathies2,9 ) .
polyostotic bone lesions and caf - au - lait macules are common , while monostotic bone lesions are rare3 ) .
endoc... | mccune - albright syndrome ( mas ) is characterized by a triad of poly / monostotic fibrous dysplasia , caf - au - lait macules and hyperfunctioning endocrinopathies including human growth hormone excess .
acromegaly as a manifestation of endocrine hyperfunction with mas is uncommon . surgical excision may be challen... |
muscular dystrophy includes loss of muscle strength and muscle mass and leads to gait disturbances resulting in compensatory kinematic and postural adaptation [ 13 ] .
eventually , patients lose their ability to stand upright and walk . clinical gait analysis of subjects with muscular dystrophy is widely used to te... | the delta - sarcoglycan - deficient hamster is an excellent model to study muscular dystrophy .
gait disturbances , important clinically , have not been described in this animal model .
we applied ventral plane videography ( digigait ) to analyze gait in bio to-2 dystrophic and bio f1b control hamsters walking on a... |
due to various biotic and abiotic stress factors under field conditions , crop plant yield reduction can reach more than 50% . among these abiotic stresses ,
salinity is the most severe environmental stress affecting more than 800 million hectares of land throughout the world [ 2 , 3 ] .
unsuitable irrigation was t... | salinity is one of the major abiotic stresses that affect crop productivity .
identification of the potential novel genes responsible for salt tolerance in barley will contribute to understanding the molecular mechanism of barley responses to salt stress .
we compared changes in transcriptome between hua 11 ( a sal... |
mucormycosis is ubiquitous in nature and humans usually have a strong natural resistance to the infection .
mucormycosis becomes pathogenic when the patient 's general resistance has been altered by metabolic disorders , immunosuppressive therapy , malignancy or other chronic debilitating disorders .
the organisms ... | a growing number of medically compromised patients are encountered by dentists in their practices .
opportunistic fungal infections such as mucormycosis usually occur in immunocompromised patients but can infect healthy individuals as well .
mucormycosis is an acute opportunistic , uncommon , frequently fatal funga... |
systematic transcriptomic analyses have unveiled a variety of non - coding rnas ranging in size from a few to several thousand bases ( miura et al , 2006 ; chekanova et al , 2007 ; shi et al , 2009 ) .
recently , a new class of small ( 1326 bases ) , transcription initiation - associated rnas , termed tiny rnas ( tir... | a new class of small rna ( ~45 bases long ) is identified in gram positive and negative bacteria .
these tssrnas are associated with rna polymerase pausing some 45 bases downstream of the transcription start site and show global changes in expression during the growth cycle . |
the goal is to ensure that safety and morbidity are minimized regardless of the technique that is employed ( 1 ) .
it is the most frequently implemented surgical intervention in children , and one third of all the men in the world are circumcised .
the procedure may also be performed for medical reasons ( 2 ) . how... | background : although male circumcision is a surgical intervention that is frequently performed in children , there is no consensus about the age at which it should be performed.objectives:the purpose of this study was to determine the best age range for routine male circumcision with respect to a child s health and th... |
an 11-year - old japanese girl presented to our department with a pigmented lesion on her right leg ( figure 1 ) .
it was a blue - gray papule approximately 4 mm in diameter with a 4-year history .
we suspected that it was a blue nevus or a pigmented reed / spitz nevus .
on dermoscopic observation , the lesion sh... | an 11-year - old girl presented to our department with a blue - gray papule approximately 4 mm in diameter .
we suspected that it was a blue nevus or a pigmented reed / spitz nevus .
on dermoscopic observation , the lesion showed homogeneous black - bluish pigmentation .
this dermoscopic feature was suggestive of... |
cysteinyl leukotrienes ( cys - lts ) are potent inflammatory lipid mediators derived from the 5-lypoxygenase ( 5-lo ) pathway of arachidonic acid ( aa ) metabolism , initially identified to have important effects on pathogenetic aspects of allergic rhinitis and bronchial asthma and approved in the late 1990s for the re... | atherosclerosis represents an important chronic inflammatory process associated with several pathophysiological reactions in the vascular wall .
the arachidonic acid , released by phospholipase a2 , is an important substrate for the production of a group of lipid mediators known as leukotrienes , which induce proinfl... |
upper extremity ( ue ) hemiparesis is a frequently encountered post - stroke impairment1 ; most of the ue functional recovery is
thought to occur within the initial 6 months after the stroke , and the extent of recovery is
very limited2 .
ue disability has a great
impact on the activities of daily living and im... | [ purpose ] this study investigated the effects of a 12-hour neuromuscular electrical
stimulation program in the evening hours on upper extremity function in sub - acute stroke
patients . [ subjects and methods ] forty - five subjects were randomized to one of three
groups : 12-hour neuromuscular electrical stimu... |
an 83-year - old male suffering from severe symptomatic aortic valve stenosis and , being a high surgical risk , received an implant of a biological aortic prosthesis ( corevalve 29 ) through the femoral artery . during the evaluation
1a ) showed sinus rhythm with an incomplete right - bundle branch block and left an... | an 83-year - old male suffering from severe symptomatic aortic valve stenosis received an implant of a biological aortic prosthesis through the femoral artery without complications .
seven days after dischargement he experienced a syncope .
the patient was wearing an ecg holter monitor that day , which showed a wid... |
the responsibilities of the specialized surface epithelium of the cornea require it to maintain tightly regulated differentiated properties .
there are numerous examples of ocular surface diseases in which the corneal - specific epithelial qualities are not maintained and significant anterior eye physiologic perturba... | purpose : gg - h whole transcriptome array analysis suggested involvement of pinin ( pnn ) in the alternative splicing of multiple long non - coding rnas ( lncrnas ) .
to further investigate pnn s role in regulating the alternative splicing of lncrnas in a corneal epithelial context , we performed detailed analyses f... |
stress is a non - specific biological reaction , which occurs in response to physical injuries
and stimulations imparted to the body , and it modifies the immune system .
in particular , physical stress excites
exacerbation of the sympathetic nervous system and increase heartbeat , and imparts
negatively influe... | [ purpose ] this study aims to examined the effect of the self - myofascial release induced
with a foam roller on the reduction of stress by measuring the serum concentration of
cortisol .
[ subjects and methods ] the subjects of this study were healthy females in their
20s .
they were divided into the experi... |
ciprofloxacin is a fluoroquinolone derivative in veterinary medicine with outstanding antibacterial activity primarily against gram - negative pathogens , but also gram - positive bacteria and some chlamydia , mycoplasma , and many mycobacterium species .
the pharmacokinetics of ciprofloxacin has been investigated in... | we evaluated the pharmacokinetics of ciprofloxacin in serum ( n = 6 ) and urine ( n = 4 ) in goats following a single intravenous administration of 4 mg / kg body weight .
the serum concentration - time curves of ciprofloxacin were best fitted by a two - compartment open model .
the drug was detected in goat serum ... |
tyrosine kinase inhibitors ( tkis ) , a form of targeted therapy , redefined the oncologic treatment of multiple malignancies , ranging from chronic myelogenous leukemia to subtypes of non - small cell lung cancer .
the first one of this class was imatinib , which revolutionized the treatment of chronic myelogenous l... | ibrutinib , an irreversible oral inhibitor of bruton 's tyrosine kinase , has been used in the treatment of patients with multiple hematologic malignancies . a 59-year - old male with chronic lymphocytic leukemia
was treated with 420 mg / day of ibrutinib .
no evidence of bruising or diarrhea was noted .
the trea... |
obstructive uropathy occurs with frequency of 1 in 1000 live births . in the course of the disease it leads to renal dysplasia , oligohydramnios and lung hypoplasia .
morbidity related to the last 2 symptoms is high , with rates up to 63% .
indication to in utero operations is diagnosed bilateral hydronephrosis con... | summarybackgroundfetal surgery , also referred to as in utero , prenatal or intrauterine surgery , consists of treatment of congenital malformations during the fetal period .
the idea of treating malformations diagnosed in the course of intrauterine life dates back to 1963 , when lilly performed the first blood trans... |
we
describe the first method for production of mechanically planar
chiral rotaxanes in excellent enantiopurity without the use of chiral
separation techniques and , for the first time , unambiguously assign
the absolute stereochemistry of the products .
this proof - of - concept
study , which employs a chir... | |
conventional radiological procedures are a significant source of radiation exposure to the population , and its use has increased substantially over the past decades . among all conventional radiographic examinations ,
lumbar spine radiography is associated with the highest radiation dose , as it is responsible for t... | introduction : collimating the primary beam to the area of diagnostic interest ( adi ) has been strongly recommended as an effective method to reduce patient s radiation dose and to improve image quality during radiology practice .
lack or inadequate collimation results in excessive radiation dose to patients and det... |
stress urinary incontinence ( sui ) is an involuntary leakage of urine with increased intraabdominal pressure caused by weakness of the pelvic floor musculature , including the bladder neck and proximal urethra , or intrinsic sphincter deficiency .
sui is the most common form of urinary incontinence in women , and ab... | purposethe transobturator adjustable tape ( toa ) sling operation is an effective procedure that allows for correction of postoperative incontinence or obstruction through adjustment of the mesh tension . during the operation ,
the outer cylinder of a ballpoint pen was used for proper mesh placement with less dissect... |
femoral neck fracture is a frequent and severe injury in the elderly with associated high mortality and morbidity .
the incidence of these fractures has increased with improvement in life expectancy and is expected to double in the next 20 years and triple by 2050.1 mortality rate of 20 - 30% in the year following th... | background : fractured neck of femur is a frequent and severe injury in elderly patients with consequent high morbidity and mortality .
hemiarthroplasty is an established treatment modality for displaced intracapsular femoral neck fractures in elderly patients above 60 years .
this study analysed the early function... |
hemophagocytic lymphohistiocytosis ( hlh ) 1 is a rare and lifethreatening hyperinflammatory syndrome caused by genetic mutations ( primary hlh ) or systemic acquired conditions ( secondary hlh ) which in adults is most commonly associated with hematological malignancies 2 , 3 .
although primary and secondary hlh hav... | key clinical messagehemophagocytic lymphohistiocytosis ( hlh ) should be considered in the differential diagnosis of adult patients with white matter disease .
brain involvement can be lifethreatening and should prompt aggressive therapy . even after hlh remission , the possibility of subsequent deterioration due to ... |
a male baby , delivered normally and spontaneously after a full - term pregnancy , was well during the first 28 hours of life .
he then became lethargic and hypotonic , and the shallow respiration which began at that point progressed to intermittent apnea , requiring mechanical ventilation . on the 4th day , brain co... | nonketotic hyperglycinemia ( nkh ) is a rare metabolic brain disease caused by deficient activity of the glycine cleveage system .
localized proton mr spectroscopy ( echo - time 166 msec ) , performed in an infant with the typical clinical and biochemical features of neonatal nkh , showed a markedly increased peak in... |
identifying lymphatic vessels is a key step in lymphatico - venous anastomosis . because lymphatic vessels are thin and fluid inside is transparent with faint color , it is not easy to spot them with bare eyes .
indocyanine green ( icg ) lymphography with infrared camera is one of the most powerful tools for identify... | indocyanine green lymphography , displayed as infrared image , is very useful in identifying lymphatic vessels during surgeries .
surgeons refer the infrared image on the displays as they proceed the operation .
those displays are usually placed on the walls or besides the operation tables .
the surgeons can not... |
the incidence of differentiated thyroid cancer ( dtc ) has been increasing during the last few decades , mostly attributable to better detection of small papillary cancer as a result of improved diagnostic accuracy .
however , improved detection does not fully explain significant increase in tumours with adverse path... | objective .
although differentiated thyroid cancer ( dtc ) usually has an indolent course , some cases show a poor prognosis ; therefore , risk stratification is required .
the objective of this study is to compare the predictive ability of classical risk stratification systems proposed by the european thyroid asso... |
access to accurate and reliable data is an important prerequisite for exploring the cost - effectiveness of healthcare interventions .
in particular , information about the numbers , rates and average costs of common invasive procedures , might help policy makers in resource allocation and payment system .
in addit... | background : the aim of this study was to estimate the frequency and rate of the first 50 common types of invasive procedures in iran.methods:data about the number of all invasive procedures and each type of procedure that were conducted in iran in 2010 were collected using the main insurance organizations database .
... |
more than 60% of patients with major depressive disorder do not achieve remission following treatment with an adequate course of at least one antidepressant.1,2 for patients who do not obtain adequate benefit from antidepressant therapy , adjunctive therapy with an atypical antipsychotic is one treatment option.3,4 ari... | background : effective management of major depressive disorder often includes the long - term use of multiple medications , and the longer - term utility and safety of adjunctive aripiprazole has not been evaluated in a controlled setting.patients and methods : patients ( n = 706 ) completing one of two 14-week double ... |
the study published by schlenk and colleagues in the previous issue of critical care was initiated by clinical experience that , after subarachnoid hemorrhage , hyperglycemia is strongly associated with complications and impaired neurological recovery .
utilizing intracerebral microdialysis and bedside biochemical mo... | following subarachnoid hemorrhage , hyperglycemia is strongly associated with complications and with impaired neurological recovery . targeted insulin therapy for glycemic control might , on the contrary , have harmful effects by causing too low cerebral glucose levels .
the study published by schlenk and colleagues ... |
a 53-year - old indian male employed in dubai , uae presented
with a sudden onset of foreign body sensation in his left eye while
at work for which he used an eyewash from the first - aid kit .
this
was followed by an acute bout of pain , redness and watering which
was attributed to the eyewash being past the... | a rare occurrence of ocular subconjunctival dirofilariasis in a
53-year - old healthy indian male working in dubai , uae presenting
with an acute red eye is reported .
surgical excision under topical
anesthesia was carried out uneventfully in the outpatient clinic . the
live worm removed from the subconjuncti... |
chronic renal disease is a major health concern that incurs poor health consequences and high health care costs ,
with greater prevalence among the elderly .
in the last two decades
, the number of the elderly patients with chronic renal failure has increased in most countries .
hence , in terms of age pattern... | abstractbackground : the chronic kidney disease is a major health concern . the number of the elderly people with chronic renal failure has increased across the world .
dialysis is an appropriate therapy for the elderly , but it involves certain challenges . the present paper reports uncertainty as part of the elderl... |
the increase in the range of options available for health and disease management , coupled
with the shift towards greater patient involvement in recent years , has led to a profusion
of decision aids and related support systems aimed at patient , clinician and medical
team .
this has been followed by the develo... | a theory - based instrument for measuring the quality of decisions made using any form of
decision technology , including both decision - aided and unaided clinical consultations is
required to enable person- and patient - centred care and to respond positively to
individual heterogeneity in the value aspects of ... |
side effects of epinephrine such as increased myocardial oxygen demand and consumption , decreased myocardial atp with proarrhythmic effects , or increased intrapulmonary shunting and myocardial dysfunction during the post - resuscitation period are well known [ 1 , 2 ] .
vasopressin is a potent vasopressor that coul... | backgroundsurvival after cardiopulmonary resuscitation ( cpr ) using standard vasopressor therapy is disappointing .
vasopressin is a potent vasopressor that could become a useful therapeutic alternative in the treatment of cardiac arrest.aimsthe aim of this prehospital prospective cohort study was to assess the infl... |
in malawi , queen elizabeth central hospital is the government - funded hospital for blantyre district , serving 1 million persons . from january 1998 through december 2004 , persons from the community who came to the hospital with fever ( adults > 14 years , axillary temperature > 37c ; and children < 14 years and > 1... | to determine the prevalence of invasive nontyphoid salmonellosis and typhoid fever in malawi and south africa , we compared case frequency and patient age distribution . invasive nontyphoid salmonellosis showed a clear bimodal age distribution ; the infection developed in women at a younger age than in men .
case fre... |
pb was collected before transplantation from patients with type 1 diabetes undergoing pancreas or pancreas / kidney transplant at san raffaele hospital .
these patients donated one pln , which was collected during the surgical procedure using scissors ( supplementary fig .
five to 10 plns were also collected from t... | objectiveautoimmune diseases , including type 1 diabetes , are thought to have a th17-cell bias and/or a t - regulatory cell ( treg ) defect .
understanding whether this is a hallmark of patients with type 1 diabetes is a crucial question that is still unsolved , largely due to the difficulties of accessing tissues t... |
postoperative adhesion is one of the major complications of strabismus surgery that can cause motility problems that affect the surgical outcomes [ 1 , 2 ] . due to the fact that the suppression of inflammation is a key element in the prevention of further fibrovascular proliferation and scar formation in the conjuncti... | purpose .
the purpose of this study was to evaluate the efficacy of dried human amniotic membrane ( am ) in reducing the postoperative inflammatory response and scarring after strabismus surgery .
methods .
the inflammatory response at the extraocular muscle reattachment site was analyzed after superior rectus ( ... |
psoriasis , a common inflammatory skin disorder affecting 1 - 2% of individuals in western societies , is caused by genetic predisposition and can be triggered or affected by various environmental provoking factors , such as mechanical stress ( koebner phenomenon ) , infections , emotional stress , diet , body mass ind... | this study was carried out to examine the possible role of interleukin-1 ( il-1 ) in the functional insufficiency of regulatory t cells in psoriasis , by comparing the expression of il-1 receptors on healthy control and psoriatic t cells .
patients with moderate - to - severe chronic plaque psoriasis and healthy volu... |
matrix metalloproteinases ( mmps ) are zinc - dependent endopeptidases that play a central role in various physiological processes and pathological conditions including cancer and inflammatory diseases
. one of the main problems for developing a new class of drugs as mmp inhibitors is the issue of selectivity .
thi... | matrix metalloproteinases ( mmps ) have distinctive roles in various physiological and pathological processes such as inflammatory diseases and cancer .
this study explored the performance of eleven scoring functions ( d - score , g - score , chemscore , f - score , pmf - score , posescore , rankscore , dsx , and x -... |
environmental or nutritional estrogenic toxicants are thought to mediate developmental and carcinogenic pathologies .
estrogen receptor ( er ) measurements are currently used to predict hormonal responsiveness ; therefore all er subpopulations should be considered .
we have been involved in the immunoidentification... |
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