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pathogenicity within the genus yersinia typically relies on the presence of the virulence plasmid pyv encoding a type 3 secretion system ( t3ss ) .
the enteropathogenic species yersinia enterocolitica is subdivided into nonpathogenic ( biotype 1a ) , high - pathogenic ( biotype 1b ) and low - pathogenic ( biotypes 25... | we report the nucleotide sequence of two novel cryptic plasmids ( 4357 and 14 662 base pairs ) carried by a yersinia enterocolitica biotype 1a strain isolated from pork .
as distinguished from most biotype 1a strains , this isolate , designated 07 - 04449 , exhibited adherence to eukaryotic cells .
the smaller plas... |
obesity has always been thought to be a risk factor for diabetes and maximum numbers of diabetics are obese ; however , some studies in india have reported that most of the diabetics in india have normal range of body mass index and have reported a high prevalence of lean diabetics .
the aim of this study was to find... | introduction : obesity has always been thought to be a risk factor for diabetes ; however , some studies in india have reported that even lean people are prone to diabetes .
we conducted this study to see if this holds true for this part of the country.objectives:to determine the prevalence of lean type 2 diabetes me... |
the success of transplantation largely depends on the compatibility of human leukocyte antigens ( hla ) .
hla is also known as the main histocompatibility complex , which is encoded by highly polymorphic set of genes located on the short arm of chromosome 6 ( chr 6p21.1 - 6p21.3 ) , and play a key role in the immune ... | background : human leukocyte antigen ( hla ) is comprised of a highly polymorphic set of genes which determines the histocompatibility of organ transplantation . the present study was undertaken to identify hla class i and class ii allele , genotype and haplotype frequencies in renal transplant recipients and donors fr... |
it is a rare condition in children with only few cases been reported in literature .
we report a case of bronchobiliary fistula which occurred as a complication of ruptured liver abscess and this complication has not been reported earlier .
a 3-year - old girl presented with complaints of fever , cough and respirat... | bronchobiliary fistula ( bbf ) is a rare condition , defined by the presence of abnormal communication between biliary tract and bronchial tree .
we describe a 3-year - old child who developed bbf after rupture of liver abscess .
she underwent exploratory laparotomy and peritoneal wash for ruptured liver abscess . ... |
an 18-year - old female patient was referred from the department of prosthodontics regarding inadequate clinical crown heights for full mouth prosthetic rehabilitation .
on intra - oral examination , the patient revealed short clinical crowns , occlusal wear with exposed dentin in the posterior teeth , and asymmetry ... | full mouth rehabilitation includes a promising treatment planning and execution thus fulfilling esthetic , occlusal , and functional parameters maintaining the harmony of the stomatognathic system .
crown lengthening procedures have become an integral component of the esthetic armamentarium and are utilized with incr... |
in the previous issue of critical care , caille and colleagues evaluated the ability of transthoracic echocardiography ( tte ) to predict cardiac - related weaning failure and to assess the hemodynamic changes before and 30 minutes after the start of a spontaneous breathing trial ( sbt ) .
the authors measured maxi... | cardiac - related failure of weaning from mechanical ventilation is an important reason for prolonged mechanical ventilation , intensive care unit treatment , and increased morbidity and mortality .
when transthoracic echocardiography ( tte ) is routinely performed before a weaning trial , patients at high risk of ca... |
several anaerobic bacteria from the human intestinal tract are capable of reducing azo dyes and nitropolycyclic aromatic hydrocarbons to the corresponding aromatic amines with enzymes that have azoreductase and nitroreductase activities .
the majority of bacteria with these activities belong to the genera clostridium... | |
the atrioventricular node ( avn ) is an area of specialized tissue between the atria and the ventricles of the heart and specifically acts as an electrical relay station for electrical impulses , passing from the atria to the ventricles .
the arterial blood supply of the avn , which is quite variable , was the topic ... | background : isolated right bundle branch block ( rbbb ) is a common finding in the general population .
the atrioventricular node ( avn ) artery contributes to the blood supply of the right bundle branch .
our hypothesis was that the anatomy of the avn artery and the pattern of dominancy differ between subjects wi... |
the term heterotopic pancreas is used to describe ectopic pancreatic tissue lying outside its normal location with no anatomic or vascular connection to the pancreas.1 these lesions are also termed ectopic pancreas , pancreatic rest , or aberrant pancreas .
they are typically discovered incidentally during endoscopy ... | heterotopic pancreas is usually asymptomatic and does not change throughout the patient 's life , but sometimes it can present symp - toms and complications , which are rarely discrete in the literature .
we present here a case of heterotopic pancreas in the gastric wall complicated with pseudocyst , and suggest that... |
breast cancer ( bc ) is the second most common cancer diagnosed in american women and is also the second leading cause of cancer death in women [ 1 , 2 ] .
it is estimated that , in the developed world , one in eight women will develop breast cancer in her lifetime [ 3 , 4 ] .
bc lethality is mainly caused by metas... | breast cancer ( bc ) is the second most common cancer diagnosed in american women and is also the second leading cause of cancer death in women .
research has focused heavily on bc metastasis .
multiple signaling pathways have been implicated in regulating bc metastasis .
our knowledge of regulation of bc metasta... |
osteoporosis is a skeletal disease characterized by reduction in bone mass and micro architectural changes in the bone , which leads to an increased bone fragility and an increased risk of fracture .
osteoporosis results from an imbalance between the rate of bone formation and resorption that leads to loss of bone mi... | objectiveosteoporosis is a skeletal disease characterized by reduction in bone mass and micro architectural changes in the bone , which leads to increased bone fragility .
the gold standard for the diagnosis of osteoporosis is the measurement of bone mineral density ( bmd ) by dual energy x - ray absorptiometry ( dxa... |
furcation involvements present difficult treatment problems due to the complex morphology of the area , which is considered as one of the challenging aspects of periodontal therapy [ 12 ] .
the final goal associated with periodontal therapies was the supporting apparatus replacement through the process of cementum , ... | objective : the purpose of the present randomized clinical trial study was to compare the effectiveness of bovine porous bone mineral ( bpbm ) with and without plasma rich in growth factors ( prgf ) in the treatment of mandibular class ii furcation defects.materials and methods : in seven patients , nine pairs of symme... |
metabolomics is the quantitative measurement of the dynamic multiparametric metabolic responses of living systems to pathophysiological stimuli or genetic modifications .
metabolomics is based on the determination of global metabolite profiles in biological fluids and tissues with subsequent data analysis via a range... | ultraperformance liquid chromatography coupled with quadrupole time - of - flight synapt high - definition mass spectrometry metabolomics was used to characterize the urinary metabolic profiling of diet - induced hyperlipidaemia in a rat model .
analysis was done by orthogonal partial least squares discriminant analy... |
ginseng is a long - living perennial plant that is highly valued in herbal medicine .
it has been used for over 2,000 years in some east asian countries , such as korea , china , japan , and vietnam .
the most important biologically active compounds in ginseng are called ginsenosides , which are chemically describe... | backgroundginsenoside rg3 is a promising anticancer agent .
it is usually produced by heat treatment of ginseng , in which ginsenoside rb1 is the major ginsenoside .
a kinetic study was conducted to optimize ginsenoside rg3 production by the heat treatment of ginsenoside rb1.methodsginsenoside rb1 was heated using ... |
thyroid hormones ( th ) play an important role in regulating energy balance , metabolism of glucose , and lipids . while th oppose the action of insulin and stimulate the hepatic gluconeogenesis and glycogenolysis they up - regulate the expression of genes such as glucose transporter type-4 ( glut--4 ) and phosphoglyce... | objective : to determine the association between altered thyroid hormones and insulin resistance ( ir).materials and methods : eight euthyroid ( eu ) , eight hypothyroid ( ho ) , and eight hyperthyroid ( hr ) patients with no past medical history were studied in this cross - sectional study at the care institute of med... |
allergen - specific immunotherapy ( sit ) has been used to treat ige - mediated rhinoconjunctivitis , asthma , and venom hypersensitivity for almost a century .
the clinical efficacy of sit has been shown in several randomized , prospective , double blind placebo - controlled studies [ 15 ] .
a number of studies ha... | background . allergen - specific immunotherapy ( sit ) is one of the important regimens for the treatment of allergic diseases .
predictive tests for the clinical response to sit are limited . in this study
we aimed to evaluate whether specific ige / total ige levels can predict clinical improvement in monosensitiz... |
end - stage renal disease ( esrd ) is an important health problem worldwide ( 1 ) . in iran ,
the prevalence and incidence rates of esrd increased from 49.9 cases per million people in 2000 to 63.8 cases per million people in 2006 , an almost 28% increase over six years ( 2 ) .
hemodialysis patients have several ph... | background : hemodialysis patients have a high physical and psychosocial symptom burden .
there is no valid and reliable tool for assessing symptoms of hemodialysis patients in iran.objectives:the aim of this study was to determine psychometric properties of the persian version of the dialysis symptom index ( dsi).pa... |
tubulin / microtubule - interacting
drugs are used successfully for
treatment of a wide variety of human cancers .
they are commonly classified
into two major categories : microtubule - stabilizing ( e.g. , taxanes
and epothilones ) and microtubule - destabilizing drugs ( e.g. , vinca
alkaloids and colchici... | to
block the metabolically labile sites of novel tubulin inhibitors
targeting the colchicine binding site based on smart , abi , and pat
templates , we have designed , synthesized , and biologically tested
three focused sets of new derivatives with modifications at the carbonyl
linker , the para - position in... |
these become more apparent in pathological conditions such as vascular occlusive diseases6,8,16 ) . for example , diminished flow in the basilar artery ( ba ) or vertebral artery ( va ) without any symptoms of vertebrobasilar insufficiency suggested that posterior circulation was supplied from single or multiple collat... | spontaneous bilateral cerebellar infarction in the territory of the superior cerebellar arteries is extremely rare .
occasionally there have been reports of bilateral cerebellar infarction due to vertebrobasilar atherosclerotic occlusion or stenosis , whereas no report of bilateral cerebellar infarction due to compli... |
the standard recommendation for the surgical correction of hydrosalpinx before in vitro fertilization ( ivf ) assumes that the patient is a suitable candidate for laparoscopy .
for example , extensive pelvic adhesions and an increased risk for bowel injury may make abdominal access unsafe or difficult for some patien... | essure ( bayer ) received approval from the u.s .
food and drugs administration as a permanent non - hormonal contraceptive implant in november 2002 .
while the use of essure in the management of hydrosalpinx prior to in vitro fertilization ( ivf ) remains off - label , it has been used specifically for this purpos... |
because cavefish are blind , it was impossible to use the classical mirror test that most researchers working on agonistic behavior use ; so we used a resident - intruder assay modified from espinasa and colleagues ( fig .
, we counted the number of attacks between the two fish , and the patterns of attacks along... | within the species astyanax mexicanus , there are several inter - fertile populations of river - dwelling sighted fish and cave - dwelling blind fish which have evolved morphological and behavioral adaptations . we have recently reported a developmental and neurophysiological basis for the loss of aggressive behavior i... |
the use of mathematical models and computer simulations in engineering , hydrology , and various fields in the process of decision making is progressively gaining more acceptances .
models are useful tools for representing the detailed and complex real world with a more simple and understandable structure and can b... | furrow irrigation proceeds under several soil - water - furrow hydraulics interaction dynamics .
the soil erosion consequences from such interactions in furrow irrigation in samaru had remained uncertain . a furrow irrigation - induced erosion ( fiie ) model was used to simulate the potential severity of soil erosion... |
the process of dna methylation at the 5-carbon position of cytosine is a critical epigenetic mechanism in the regulation of gene expression .
5-methylcytosine constitutes 28% of all cytosines in human genomic dna and impacts a broad range of biological functions and pathological processes including gene expression , ... | dna methylation is the most well studied epigenetic modification in cancer biology .
5-hydroxymethylcytosine is an epigenetic mark that can be converted from 5-methylcytosine by the ten - eleven translocation gene family .
we recently reported the loss of 5-hydroxymethylcytosine in melanoma compared to benign nevi ... |
roku ycia zwizane jest z wyszym ryzykiem i niesie ze sob wiksze wyzwania ze strony caego personelu medycznego .
przedstawienie wczesnych i odlegych wynikw leczenia kardiochirurgicznego choroby wiecowej i wady aortalnej u pacjentw powyej 80 . roku ycia .
badan grup stanowio 96 chorych w wieku powyej 80 lat , ktrych ... | backgroundin recent years , patients over 80 years of age have been a growing group of individuals referred to cardiac surgeons .
they pose a serious challenge and usually require a multidisciplinary approach.aimthe aim of this study was to evaluate the early and late outcomes of cardiosurgical treatment of patients ... |
the diagnostic and statistical manual of mental disorders ( dsm - iv - tr ) includes panic disorder ( pd ) with agoraphobia among its list of anxiety disorders .
panic attacks are described as a period of intense fear or anxiety accompanied by somatic and psychological symptoms .
these symptoms include a lack of ... | panic disorder refers to the frequent and recurring acute attacks of anxiety .
objective : this study describes the
routine use of mobiles phones ( mps ) and investigates the appearance of possible emotional alterations or symptoms related
to their use in patients with panic disorder ( pd ) .
background : we co... |
the natural history of polypoidal choroidal vasculopathy ( pcv ) is variable and may be benign or result in permanent visual morbidity.1 treatment of pcv is indicated if their central involvement , particularly if one eye has lost perception of color vision .
current treatment modalities include vascular endothelial ... | a 55-year - old male presented with serous retinal detachment over 3 months in his right eye .
his left eye was blind due to retinal pigment epithelium detachment since 1997 with atrophy of the neurosensory retina .
fluorescein angiography had previously shown bilateral polypoidal choroidal vasculopathy ( pcv ) .
... |
animals and peritoneal macrophages - swiss and c3h / hej mice were
obtained from north fluminense state university ( uenf ) and oswaldo cruz foundation
animal facility , respectively .
peritoneal washes were performed on male mice ( 25 - 30 g )
using hank s solution and the resident macrophages were seeded on g... | lipid bodies [ lipid droplets ( lbs ) ] are lipid - rich organelles involved in lipid
metabolism , signalling and inflammation .
recent findings suggest a role for lbs in
host response to infection ; however , the potential functions of this organelle
in toxoplasma gondii infection and how it alters macrophage ... |
relapsing fever is an infection spread by the vectors of lice and ticks ( jump et al .
the most important agent is b. persica , which causes the large majority of human cases and has the widest distribution ( dschunkowsky 1913 , baltazard et al .
1950 , colin de verdire et al . 2011 ) . in eurasia , dschunkowsky ( ... | background : endemic relapsing fever remains under diagnosed in our area according to a low index of suspicion among clinicians , as well as its difficult diagnosis .
the goal of this study was to present the epidemiological aspects of the disease in western iran.methods:in this analytical - descriptive cross - secti... |
a total of eight , eight - week - old male sprague - dawley rats were used in this study .
then the tissues from the cerebrum , cerebellum , left ventricular free wall , whole atrial tissue , psoas muscle , femoral muscle , liver , spleen , kidney , and aorta were immediately collected and divided into several small ... | backgroundhousekeeping genes , which show constant protein expression patterns between different tissue types , are very important in molecular biological studies as an internal control for protein research.methodsthe protein expression profiles of seven housekeeping genes ( hprt1 , ppia , gys1 , tbp , ywhaz , gapdh an... |
the online version of this article ( doi:10.1007/s40121 - 013 - 0022 - 6 ) contains supplementary material , which is available to authorized users .
vancomycin has long been the workhorse agent for management of infections due to methicillin - resistant staphylococcus aureus ( mrsa ) ; however , its clinical use is ... | introductionlittle is known regarding age - related risk of nephrotoxicity during vancomycin therapy after the publication of the 2009 vancomycin consensus guidelines for therapeutic drug monitoring .
we sought to evaluate incidence and risk factors for acute kidney injury in three age groups.methodsmatched cohort st... |
chronic kidney disease ( ckd ) is a growing public health problem [ 14 ] with evidence pointing to an increasing incidence and prevalence worldwide [ 5 , 6 ] .
however , it is grossly underdiagnosed in nigeria and other developing countries . the hospital frequency in nigeria ranges between 1.6 and 8% of hospital adm... | background . cognitive impairment with its negative effect on quality of life has been reported in chronic kidney disease ( ckd ) .
the paucity of the literature on cognitive impairment in africans with ckd prompted this study .
objectives . to determine the frequency and pattern of cognitive impairment in patients... |
endodontically treated teeth have decreased moisture content and suffer coronal destruction from dental caries , which reduces stiffness leading to fractures from previously existing restorations.1 this results in an increase in the likelihood of fracture of treated tooth during the function .
the restoration of the ... | background : debonding is one of the frequent causes of failure experienced in fiber - reinforced composite posts , and establish along post space - dentin adhesive interface .
the purpose of this study was to assess push - out bond strength of a fiber - reinforced post system using four different resin cements.mater... |
pregnancy luteoma is a rare nonneoplastic tumor - like lesion of the ovary that was first described by sternberg and barclay in 1966 , and to date , fewer than 200 cases have been reported in literature .
it is usually discovered incidentally at the time of a cesarean section or during postpartum tubal ligation .
a... | pregnancy luteomas are rare , nonneoplastic lesions of the ovary thought to be caused by the hormonal effects of pregnancy .
most of these patients are asymptomatic with the ovarian enlargement being incidentally discovered during imaging or surgery .
some patients develop hirsutism or virilization during late preg... |
to promote the osteoblast responses to titanium ( ti ) oral implants , the effects of surface microgrooves on in vitro cell behaviors have been reported extensively .
ti surface microgrooves were reported to induce changes in cell morphology , 1 cell - substratum adhesion,2 and gene expression3 in vitro .
microgroo... | purposethe aim of this pilot study was to investigate the effect of etched microgrooves on the hydrophilicity of ti and osteoblast responses.material and methodsmicrogrooves were applied on ti to have 15 and 60 m width , and 3.5 and 10 m depth by photolithography , respectively .
further acid etching was applied to c... |
a central goal of quantum chemistry is
to elucidate mechanisms
and energetics of reactions .
both can be obtained from minimum ( free )
energy paths connecting reactants to products .
methods such as conjugate peak refinement , the nudged elastic band , the string method , and transition path sampling refine ... | finding transition paths for chemical
reactions can be computationally
costly owing to the level of quantum - chemical theory needed for accuracy .
here , we show that a multilevel preconditioning scheme that was recently
introduced ( tempkin et al .
j. chem .
phys.2014 , 140 , 184114 ) can be used to accel... |
severe acute malnutrition ( sam ) affects nearly 20 million children under five and contributes to one million child deaths yearly [ 1 , 2 ] .
severe wasting ( marasmus ) is defined as weight - for - height ( wh ) below 3 standard deviations ( sd or z - scores ) or mid - upper arm circumference ( muac ) < 115 mm [ 2... | objective .
this study investigated the treatment outcomes and determinant factors likely to be associated with recovery rate . methods . a retrospective chart review ( rcr )
was performed on 348 patients who were enrolled in the outpatient care ( opc ) during the study period . results .
of the 348 cases , 33.6%... |
negative life events manifested as psychological stress and depression are common in day - to - day life , emphasizing the relationship between the person and environment .
stress is said to influence the host defenses , exerting an immunosuppressive effect , increasing one 's vulnerability to disease.[24 ] cytokines... | background : clinical and epidemiological data suggest that negative life experience events , like depression , may contribute to an increased susceptibility to periodontal disease.aim:to study the association between psychological stress and chronic periodontitis.materials and methods : one hundred and eleven dentate ... |
autism spectrum disorders ( asd ) are defined as a heterogeneous group of neurodevelopmental disorders characterized by impairments in communication and social interactions along with restrictive and repetitive behaviors .
the incidence of asd in the united states is currently estimated to be 1 in 68 individuals , an... | the association of autism spectrum disorders with oxidative stress , redox imbalance , and mitochondrial dysfunction has become increasingly recognized . in this study ,
extracellular flux analysis was used to compare mitochondrial respiration in lymphoblastoid cell lines ( lcls ) from individuals with autism and una... |
the study setting was kpnc , which provides comprehensive medical services through 14 delivery hospitals and 23 outpatient clinics to > 3 million members located in a 14-county region of northern california .
the demographic make - up of the kpnc membership is well representative of the population living in the geogr... | objectiveto examine whether the association between gestational diabetes mellitus ( gdm ) and bmi category varies by racial / ethnic group.research design and methodsin a cohort of 123,040 women without recognized pregravid diabetes who delivered babies between 1995 and 2006 at kaiser permanente of northern california ... |
the experimental protocols used in this study were approved by the committee on animal research at our institution .
fifteen dogs ( 12 - 16 months in age , 16 - 20 kg each , 10 males and 5 females ) were infected with the metacercariae of p. westermani isolated from the muscles and gills of the freshwater crayfish , ... | objectiveto investigate the serial ct findings of paragonimus westermani infected dogs and the microscopic structures of the worm cysts using micro-ct.materials and methodsthis study was approved by the committee on animal research at our institution .
fifteen dogs infected with p. westermani underwent serial contras... |
gastric cancer ( gc ) is the third most common cause of cancerrelated mortality worldwide , and has a particularly high incidence in asian countries including china and japan .
although the incidence of gastric cancer has been reduced in certain developed countries over the past few decades , there are still over 1 m... | gastric cancer ( gc ) is the third leading cause of cancer - related deaths .
more than 80% of the diagnosis was made at the advanced stages of the disease , highlighting the urgent demand for novel biomarkers that can be used for early detection .
recently , a number of studies suggest that circulating micrornas (... |
here , we describe a patient who presented with anterior ischemic optic neuropathy ( aion ) and
subsequently developed uveitis .
a 69-year - old man was referred to our hospital and initially presented with best - corrected visual
acuities ( bcva ) of 20/40 ( right eye ) and 20/1000 ( left eye ) and relative affe... | introduction : here , we describe a patient who presented with anterior ischemic optic neuropathy ( aion ) and
subsequently developed uveitis.case:a 69-year - old man was referred to our hospital and initially presented with best - corrected visual
acuities ( bcva ) of 20/40 ( right eye ) and 20/1000 ( left eye ) a... |
carbon dioxide ( co2 ) is the major anthropogenic greenhouse gas ( ghg ) and its atmospheric concentration has risen by approximately 100 parts per million since the industrial revolution . with current co2 accumulation rates , global temperatures are predicted to increase between 1.4c and 5.8c by the end of this centu... | root system architecture ( rsa ) describes the dynamic spatial configuration of different types and ages of roots in a plant , which allows adaptation to different environments .
modifications in rsa enhance agronomic traits in crops and have been implicated in soil organic carbon content .
together , these fundame... |
melt glycerin jelly in a 55 c degree water bath for 20 - 30 minutes until it becomes a homogenous liquid .
swirl , but do not shake the bottle to avoid the formation of bubbles . while the jelly melts , apply a thin layer of glycerol using a kimwipe on a clean glass slide ( optional ) .
pipette 1 to 1.5 ml of melte... | several well - known morphogenetic gradients and cellular movements occur along the dorsal / ventral axis of the drosophila embryo . however , the current techniques used to view such processes are somewhat limited .
the following protocol describes a new technique for mounting fixed and labeled drosophila embryos fo... |
the flowering plants are extremely diverse in their morphology , growth habit , environmental adaptation , and nuclear genome content .
plant genomes tend to be large and complex , varying in size from 125 million base pairs ( mbp ) for arabidopsis thaliana to 124,852 mbp for fritillaria assyriaca . despite so muc... | expressed sequence tags ( est ) are potential source for the development of genic microsatellite markers , gene discovery , comparative genomics , and other genomic studies . in the present study ,
7630 ests were examined from ncbi for ssr identification and characterization .
a total of 263 ssrs were identified wi... |
diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion and insulin action or both .
the chronic hyperglycemia is associated with long - term damage , dysfunction , and failure of normal functioning of various organs , especially the eyes , kidneys... | the prevalence of diabetes mellitus is rising all over the world .
uncontrolled state of hyperglycemia due to defects in insulin secretion / action leads to a variety of complications including peripheral vascular diseases , nephropathy , neuropathy , retinopathy , morbidity , and/or mortality .
large body of evide... |
parent radionuclide , tungsten-188 ( w-188 ) with a half life equal to 69.4 d , is produced in a nuclear reactor by irradiation of tungsten oxide , 96.07% enrichment in tungsten-188 ( w-188 ) with thermal and high energy neutrons .
the decay chain from a 100% pure target w-186 according to neutron flux and irradia... | rhenium-188 ( re-188 ) is a high energy -emitting radioisotope obtained from the tungsten-188/rhenium-188 ( w-188/re-188 ) generator , which has shown utility for a variety of therapeutic applications in nuclear medicine , oncology , and interventional radiology / cardiology .
re-188 decay is accompanied by a 155 ke... |
tooth whitening continues to be a rapidly growing area in esthetic dentistry because tooth color and brightness is so important for patients .
dentists apply various treatment methods for this purpose such as microabrasion , macroabrasion and bleaching . nowadays ,
the whitening effects of these toothpastes are usu... | introduction : whitening toothpastes which have been accepted in populations may affect properties of enamel and restorative materials .
the aim of this study was to compare the microhardness of human enamel and z250 microhybrid composite resin after brushing with two whitening toothpastes.materials and methods : in ... |
the development and progression of atherosclerosis involves the immune response and inflammation . among the major markers of inflammation are two proteins of the pentraxin superfamily : the acute phase proteins c - reactive protein ( crp ) and pentraxin 3 ( ptx3 ) .
the pentraxins are acute phase proteins comprising... | the effect of lipoprotein apheresis ( direct adsorption of lipids , dali ) ( la ) on plasma levels of pentraxin 3 ( ptx3 ) , an inflammatory marker that reflects coronary plaque vulnerability , and expression of ptx3 mrna was evaluated in patients with hyperlp(a)lipoproteinemia and angiographically defined atherosclero... |
gigantomastia is a breast disorder marked by exaggerated rapid growth of the breasts , generally bilaterally . since this disorder is very rare and
has been reported only in sparse case reports its etiology has yet to be fully established .
treatment is aimed at improving the clinical and psychological symptoms and... | background : gigantomastia is a breast disorder marked by exaggerated rapid growth of the breasts , generally bilaterally . since this disorder is very rare and has been reported only in sparse case reports its etiology has yet to be fully established .
treatment is aimed at improving the clinical and psychological s... |
chronic obstructive pulmonary disease ( copd ) is a common disease in denmark because of the very high smoking prevalence among both men and women in the past 5 decades .
the prevalence of copd in denmark is thus , among the highest in the western world .
it has been estimated that ~400,000 of the total population ... | aim of databasethe danish register of chronic obstructive pulmonary disease ( drcopd ) is a nationwide database aiming to describe the quality of treatment of all patients with chronic obstructive pulmonary disease ( copd ) in denmark.study populationdrcopd comprises data on all patients with a diagnosis of copd . in t... |
characterization of gabab1j cdna and mrna an
oligo(dt ) primed double - stranded cdna made from the cortex / cerebellum of
7-day - old rats ( 34 ) was
screened with a p - labeled sd - specific cdna hybridization probe as
described ( 27 ) . for northern
blot analysis ,
total rna was isolated from mouse... | gabab receptors are the g - protein - coupled receptors for
-aminobutyric acid ( gaba ) , the main inhibitory neurotransmitter in the
brain .
gabab receptors are promising drug targets for a wide
spectrum of psychiatric and neurological disorders .
receptor subtypes exhibit
no pharmacological difference... |
type 2 diabetes mellitus ( t2 dm ) is commonly associated with obesity and results from defects in insulin secretion and/or diminished sensitivity of target tissues to insulin action .
they participate in posttranscriptional regulation of gene expression , therefore , to directly control the expression of a large por... | han population is six times as likely as kazak population to present with type 2 diabetes mellitus ( t2 dm ) in china .
we hypothesize that differential expression and cpg methylation of mir-375 may be an ethnic - related factor that influences the incidence of t2 dm . the expression level of mir-375 was examined usi... |
controlled release drug delivery systems have been the research hot spot for the formulation scientists from the last few decades .
these delivery systems became popular due to their sustained release and reduction in dosage frequency which leads to the patient compliance .
a number of design approaches were availa... | asymmetric membrane capsules ( amcs ) are one of the novel osmotic delivery devices which deliver a wide range of drugs in controlled manner . in the present work
, we developed and validated a semiautomatic process by fabricating a hydraulic assisted bench top model for manufacturing amcs .
the capsule walls of am... |
the reducing substrates 4-thiolumazine
and 2,4-dithiolumazine have
been used to form moiv - product complexes with xanthine
oxidase ( xo ) and xanthine dehydrogenase .
these moiv - product
complexes display an intense metal - to - ligand charge - transfer ( mlct )
band in the near - infrared region of the s... | |
olmesartan , an angiotensin ii receptor antagonist , is commonly used to control benign hypertension 1 . recently ,
three cases series 2 , 3 , 4 and several case reports 5 , 6 reported that olmesartan could induce severe spruelike enteropathy revealed by chronic diarrhea with malabsorption syndrome and weight loss . ... | key clinical messageolmesartan is an angiotensin ii receptor antagonist which may cause severe spruelike enteropathy with duodenal villous atrophy .
skin lesions may be associated as reported for the first time in our case .
clinicians should be informed of this side effect and its reversibility after suspension of... |
from october 2009 through june 2010 , fecal specimens from patients affected by 194 outbreaks from 21 states were submitted to the centers for disease control and prevention ( cdc , atlanta , ga , usa ) ; 39 ( 20% ) of the viruses were typed as gii.12 by phylogenetic analysis by using region d sequences ( 5 ) . during ... | in october 2009 , a novel gii.12 norovirus strain emerged in the united states and caused 16% of all reported norovirus outbreaks during the winter season .
sequence analysis demonstrated a recombinant virus with a p2 region that was largely conserved compared with previously sequenced gii.12 strains . |
oral and pharyngeal cancers grouped together are the sixth most common cancers in the world .
the most recent estimated world incidence of oral cancer is around 263,861 new cases for the year of 2008 . in portugal in the same year ,
oral cancer was the 6th most frequent cancer in males , with 777 new cases ( age - ... | we conducted a questionnaire survey among 602 subjects in order to analyze the awareness and knowledge on oral cancer among residents of the city of valongo in portugal .
the cancer that most subjects were aware of was breast cancer ( 99% ) .
oral cancer was the least mentioned cancer ( 68.6% ) .
there was awaren... |
the online version of this article ( doi:10.1186/s13065 - 015 - 0131 - 2 ) contains supplementary material , which is available to authorized
users .
the solubility of organic compounds in 1-octanol is important because of its direct
relationship to the partition coefficient logp used in pharmacology and environm... | background1-octanol solubility is important in a variety of applications involving
pharmacology and environmental chemistry .
current models are linear in nature and often require
foreknowledge of either melting point or aqueous solubility . here
we extend the range of
applicability of 1-octanol solubility mo... |
a cross - sectional study conducted on 296 women aged more than 34-year - old at winter of 2014 in qom , center of iran .
the study population was women that referring to health centers for seeking the health cares . to select a random sample ,
multistage sampling method was used . first according to cluster sampli... | introduction : breast cancer is the most commonly diagnosed cancers in women worldwide and in iran . it is expected to account for 29% of all new cancers in women at 2015 .
this study aimed to assess the 5 years and lifetime risk of breast cancer according to gail model , and to evaluate the effect of other additiona... |
for endodontic therapy to be successful , it is acknowledged that the root canal should be cleaned , shaped and sealed in its three dimensions19 . several materials and techniques
gutta - percha , used since 18676 , is the most commonly employed material due to its biocompatibility , dimensional stability , plasticit... | objective : the aim of this study was to evaluate the thermoplasticity of three commercial brands of gutta - percha ( tanari , dentsply 0.06 , and roeko ) , and of the tc system.materials and methods : standardized specimens were fabricated from the materials to be evaluated . specimens were placed in water at 70c for ... |
diagnostic approaches in cases of pediatric gastrointestinal ( gi ) bleeding and anemia depend on the patient s age and individual characteristics .
various etiologies , including anal fissure , intussusception , meckel s diverticulum , infection , henoch - schonlein purpura , and juvenile polyps , are responsible fo... | gastrointestinal ( gi ) bleeding in pediatric patients has several causes .
vascular malformation of the small bowel is a rare disease leading to pediatric gi bleeding . to our knowledge , few reports describe ultrasound and computed tomography findings of venous malformations involving the small bowel .
we present... |
it is a substrate for the enzyme family of glutathione s - transferases , which catalyze the formation of glutathione conjugates of xenobiotics to facilitate their transport and detoxification ( 2 ) .
stores of gsh are also a significant source of reduction equivalents , e.g. , for reactions of the glutathione peroxi... | the reduction of oxidized glutathione gssg by hydrated electrons and hydrogen atoms to form gssg is quantitative .
the radical anion dissociates into gs and gs , and the s - centered radical subsequently abstracts a hydrogen intramolecularly .
we observe sequential development of uv absorbance signatures that indic... |
in a recent issue of critical care , van de louw and haouzi report on the effects of lethal hemorrhage on blood and tissue levels of hydrogen sulfide ( h2s ) .
the role of h2s during hemorrhage is a matter of debate : while both inhaled h2s and intravenous sodium sulfide and sodium hydrosulfide improved survival [ 2 ... | the role of the gaseous mediator hydrogen sulfide ( h2s ) in hemorrhagic shock is still a matter of debate .
this debate is emphasized by the fact that available literature data on blood and tissue h2s concentrations vary by three orders of magnitude , both under physiological conditions as well as during stress stat... |
obesity , which involves chronic low - grade inflammation , has become a global epidemic .
this poses a large health burden , because excess adiposity can lead to an array of chronic diseases such as type 2 diabetes , stroke , coronary heart disease and high blood pressure .
obesity is associated with an abnormal i... | it is widely accepted that chronic inflammation contributes to the pathogenesis of obesity .
researchers have recently discovered that increased inflammatory cytokines and the infiltration and activation of macrophage cells in the adipose tissue are related to chronic obesity .
this immunologic dysregulation has le... |
congenital esophageal stenosis ( ces ) is a rare , yet significant entity because of its clinical manifestation and its association with tracheoesophageal fistula ( tef ) or esophageal atresia ( ea).1 the incidence of ces is estimated at 1 in 25,000 to 50,000 live births.2 there is associated ea in one - third of the c... | a 2-day - old preterm female neonate weighing 1.6 kg and having excessive frothing from mouth was investigated for suspected esophageal atresia and tracheoesophageal fistula .
x - ray findings of an unusually low - ending upper pouch ( up to t8 level ) and the absence of gas in abdomen lead to suspicion of an unusua... |
diabetes is a fast - growing global problem , and diabetic retinopathy ( dr ) is the leading cause of blindness among americans over 40-year old [ 13 ] .
nearly all patients with type 1 diabetes and more than 60% of those with type 2 diabetes will develop dr [ 46 ] .
diabetic retinopathy is a dual disorder with mic... | diabetic retinopathy ( dr ) is the leading cause of blindness among the american working population .
the purpose of this study is to establish a new diabetic animal model using a cone - dominant avian species to address the distorted color vision and altered cone pathway responses in prediabetic and early diabetic p... |
a 53-year - old woman visited the department of rheumatology with the chief complaint of a 3-day history of fever and chills and also presented with pain occuring in both knees at the time of the outpatient visit .
the patient 's past history included no notable medical and surgical findings . upon hematology perform... | a 53-year - old woman visited the department of rheumatology with a chief complaint of a 3-day history of fever and chills and also presented with pain occuring in both knees at the time of outpatient visit .
based on rheumatologic and hematological lab studies , ultrasonography , and a needle aspiration biopsy of th... |
to present a rare case of retinal pigment epithelium ( rpe ) rupture following yag laser posterior capsulotomy ( yag pc ) in a patient with exudative age - related macular degeneration ( amd ) .
an 85-year - old pseudophakic male patient on ranibizumab 0.5 mg/0.05 ml treatment due to exudative amd received yag pc for... | purposeto present a rare case of retinal pigment epithelium ( rpe ) rupture following yag laser posterior capsulotomy ( yag pc ) in a patient with exudative age - related macular degeneration ( amd).materials and methodsan 85-year - old pseudophakic male patient on ranibizumab 0.5 mg/0.05 ml treatment due to exudative ... |
nitrate and nitrite when ingested by human beings may have a negative impact on health .
nitrate is transformed to nitrite by the action of certain microorganisms present in the intestine .
then it may transform hemoglobin to methemoglobin by oxidizing fe ( ii ) present in the former substance to fe ( iii ) .
met... | a fast and efficient automated method using a sequential injection analysis ( sia ) system , based on the griess , reaction was developed for the determination of nitrate and nitrite in infant formulas and milk powder .
the system enables to mix a measured amount of sample ( previously constituted in the liquid form ... |
epidemiological studies purport
that the use of certain antibiotics during pregnancy increases susceptibility
to vulvo - vaginal candidiasis [ 1 , 2 ] .
this condition is generally believed to result from the suppression of a bacterial flora in the face of antibacterial
drugs that fail to inhibit candida , ... | object . to determine
if tetracycline , previously reported to increase the probability of developing symptomatic vaginal yeast infections , has a direct effect on candida albicans growth or induction of virulent phenotypes . method . in vitro ,
clinical isolates of yeast were cultivated with sublethal concentratio... |
multilevel cervical myelopathy is usually treated by posterior approaches . laminectomy permits adequate decompression of the cervical spinal cord and
is safely and easily performed but is associated with progressive spinal instability and kyphosis [ 1 , 2 ] . in recent years , laminoplasty has been widely performed ... | backgroundpreserving the c7 spinous process during cervical laminoplasty has been reported to prevent axial symptom .
some patients underwent laminectomy and fixation developed the symptom .
the objective of this article was to investigate whether axial symptom can be reduced by preserving the c7 spinous process du... |
sic nanomaterials have promising applications in electronics and photonics owing to their attractive optical , electrical , mechanical , and thermal properties .
in particular , sic nanorods have excellent mechanical and field emission properties , which find potential applications in various nanocomposite materials ... | well - crystallized-sic nanorods grown on electrospun nanofibers were synthesized by carbothermal reduction of tb doped sio2(sio2:tb ) nanofibers at 1,250 c . the as - synthesized sic nanorods were 100300 nm in diameter and 23 m in length .
scanning electron microscopy ( sem ) results suggested that the growth of the... |
atrial fibrillation ( af ) is the most common sustained arrhythmia and an important source of mortality and morbidity on a population level .
more than 6 million people in europe are affected and this is expected to double during the next 3050 years .
the estimated lifetime risk of developing af is one in four for ... | atrial fibrillation ( af ) is the most common sustained arrhythmia and an important source for mortality and morbidity on a population level . despite the clear association between af and death , stroke , and other cardiovascular events
, there is no evidence that rhythm control treatment improves outcome in af patie... |
residence in antarctica exposes humans working in the research bases to extremes of weather and photoperiod , in addition to geographic and social isolation .
the annual average solar radiation decreases with increasing latitude , and this difference is marked during winter than in midsummer in the circumpolar region... | background . altered circadian cortisol and melatonin rhythms in healthy subjects exposed to an extreme polar photoperiod results in changes in mood and sleep , which can influence cognitive performance .
materials and methods .
we assessed the circadian rhythm of 20 subjects who wintered over at maitri ( 70s ,
1... |
the middle aortic syndrome ( mas ) is an uncommon lesion characterized by severe aortic narrowing in the descending thoracic aorta , abdominal aorta , or both .
takayasu 's arteritis is a chronic , autoimmune , and potentially progressive inflammatory disease of large vessels with a preference for the aorta and its m... | the middle aortic syndrome ( mas ) is a rare condition characterized by diffuse narrowing of the descending thoracic aorta , abdominal aorta , or both .
it can be congenital or acquired due to several conditions .
we report an 8-year - old girl who developed middle aortic syndrome due to takayasu arteritis . |
the potential synergistic effect of multiple dietary and inactivity behaviours on the risk of chronic conditions , as obesity , and other health outcomes is a key issue for public health .
many adolescents fail to meet a wide diet , physical activity , and sedentary behaviour recommendations , highlighting the need t... | physical activity , nutrition , and sedentary behaviour combine to influence the risk of overweight among adolescents . this paper aims to identify psychosocial factors of different health behaviour patterns in adolescents and its association with overweight and weight control behaviours .
the 3069 adolescents of bot... |
the ear , nose , and throat ( ent ) represent a natural habitat for a broad range of microorganisms such as commensal bacteria as well as potential pathogens
. however , these bacteria can sometimes find their way to overcome the defense barriers of such locations and establish chronic infections that poses a challen... | diseases of the tonsils are becoming more resistant to antibiotics due to the persistence of bacteria through the formation of biofilms .
therefore , understanding the microbiology and pathophysiology of such diseases represent an important step in the management of biofilm - related infections .
we have isolated t... |
neurological complications due to spinal anesthesia are dysesthesia , paresthesia , cauda equina syndrome , and neuropathic joint . however , neurological complications are rare .
we report a case of neuropathic joint of knee as a complication of syrinx following postspinal anesthesia .
a 33-year - old female came ... | introduction : neurological complications due to spinal anesthesia are dysesthesia , paresthesia , cauda equina syndrome , and neuropathic joint . however , neurological complications are rare .
we report a case of neuropathic joint of knee as a complication of syrinx following postspinal anesthesia.case report : a 3... |
cystic fibrosis ( cf ) is the commonest autosomal recessive condition among caucasians and affects over 9000 people in the uk , over 30 000 in the us and 70 000 people worldwide .
those affected suffer from the direct results of mutations in the cftr gene , causing cftr dysfunction .
this leads to increased vis... | backgroundit is unclear why cystic fibrosis ( cf ) survival has improved .
we wished to quantify increases in cf median age of death in the context of general population survival improvement.methoddeath registration data analysis ( us , england & wales ( e&w)19722009).resultscf median age of death is higher in us tha... |
pulmonary sclerosing hemangioma ( psh ) is a rare benign tumor which was first described by liebow and hubbell .
psh is generally considered as benign tumor , but some reports suggested the malignant potential of this tumor . the optimal surgical strategy for treating psh has not been established . the purpose of thi... | backgroundpulmonary sclerosing hemangioma is a rare thoracic tumor , and pathophysiology or clinical course of this tumor is not yet fully described .
furthermore , there is no consensus on the standard operative procedure for this tumor.material and methodsmedical records of thirty - two patients , who underwent sur... |
daily inactivity of young children is a major problem of societies all over the world .
numerous studies proved a connection of children s activities with their future health status and the trend of progressive inactivity and obesity of children .
inactivity or lack of proper physical activity in childhood can resu... | abstractobjectivethe objectives of this study were : a ) to examine the influence of an 18-week basic artistic gymnastics program on fundamental movement skills ( fms ) development in seven - year - old children ; b ) to determine correlations between children s daily activities and successful performance of fms and ba... |
over the past ten years the involvement of glasgow 's community pharmacists in the area 's methadone maintenance program has increased dramatically . in 1993
a major review of drugs services in glasgow suggested that the high prevalence of injecting drug use prior to 1993 was because , before that date , little use w... | this article outlines the evolution of a community pharmacy - based supervised consumption of methadone program in grater glasgow .
the formalization of this program in 1994 promoted full patient compliance with the methadone regimen and reduced seepage of the drug to the illicit market .
184 of the area 's 215 com... |
the mastoid pneumatization begins on the 33 week of embryonic life , and continuous up to 8 - 9 years of age .
pneumatic cellular expansion into the remainder of the temporal bone occurs until after birth , with the stimulation caused by the presence of air within the middle ear .
the pneumatizing process then goes... | background : the mastoid pneumatization begins on the 33rd week of embryonic life , and continuous up to 8 - 9 years of age .
this air cells is important for surgical perspective .
inadvertent penetration through this anatomical feature during surgical procedures can be disastrous .
aim of this study is to determ... |
infertile couples make up approximately 10% of the worldwide population of reproductive age , and assisted reproductive technologies ( art ) currently account for 1.2% of total us live births , and up to 4% in some european countries ( nygren and andersen , 2002 ; schieve et al . , 2009 ) .
current estimates indicate... | poor responders represent more than a third of women undergoing assisted reproduction .
typically they are patients with advanced maternal age and low ovarian reserve .
however , there is a younger group that unexpectedly demonstrates impaired response to controlled ovarian hyperstimulation .
the etiologies in ma... |
supplementary material is available for this article at 10.1007/s13659 - 013 - 0024 - 9 and is accessible for authorized users .
| dendrowardol c ( 1)a novel sesquiterpenoid , with an unprecedented 4/5/6/6 tetracyclic carbon backbone , together with two known cyclopacamphane - type sesquiterpenoids ; dendronobilin i ( 2 ) and dendrobane a ( 3 ) were isolated from the stems of dendrobium wardianum warner .
the structure of 1 was established on th... |
symptoms of dryness and discomfort are often cited as major factors related to the discontinuation of contact lens wear.18 dropout rates reported in the literature range from 15.9%34%.1,5,8,9 despite the innovation of contact lens materials for daily wear / frequent replacement ( ie , silicone hydrogels ) , the contact... | purposeto evaluate whether the use of biotrue multipurpose solution ( mps ) could significantly reduce the likelihood with which patients drop out of using daily wear contact lenses ( cls ) amongst 1844-year - old frequent replacement cl wearers.methodsdaily wear cl subjects habitually using mpss ( other than biotrue m... |
health care systems not included in conventional medicine are known as complementary and alternative medicine ( cam ) .
earlier cam practitioners based their practice on tradition and intuition but recently they have been influenced by available evidence .
education and training were required to improve a cam pract... | students of ayurveda and qualified ayurveda practitioners were assessed for awareness about bibliographic databases .
one hundred and four volunteers ( age range 1764 years ; group meansd , 24.3 7.9 years ; 62 females ) participated in this cross - sectional study .
there were 3 groups .
group i had 60 undergrad... |
the use of oocyte freezing for fertility preservation is becoming more widely practiced.1 although there is evidence that the success rates of oocyte cryopreservation and subsequent thaw cycles appear to approach that of a fresh in vitro fertilization ( ivf ) cycle ( coupled with reports of numerous live births ) , ooc... | our objective is to describe a successful live birth from oocyte vitrification followed by thaw , fertilization , blastocyst culture , trophectoderm biopsy , vitrification , and subsequent thaw .
fifteen mature oocytes were frozen from a patient with uterine factor infertility .
thirteen oocytes survived the thaw ,... |
each year , an estimated 350,000 infants , mostly in low - resource countries , acquire human immunodeficiency virus infection from their mothers [ 1 , 2 ] .
resource - limited countries in sub - saharan africa continue to bear the greatest burden of maternal to child transmission and account for the highest number o... | background . research related to prevention of maternal to child transmission ( pmtct ) of hiv is dynamic and rapidly changing and has provided evidence - based interventions and policies for practitioners .
however , it is uncertain that research and policy guidelines are adequately being disseminated and implemente... |
przepuklina pucna definiowana jest jako przemieszczenie si tkanki pucnej pokrytej opucn cienn poza prawidowe granice jamy opucnej przez patologiczne otwory w cianie klatki piersiowej .
przeprowadzajc zabiegi torakochirurgiczne , autorzy korzystali z rnych metod rekonstrukcji ciany klatki piersiowej i naprawy zamanych... | introductionin this paper we present a new method of pulmonary hernia surgical treatment .
pulmonary hernia is a rare pathology .
the first description of pulmonary hernia was made by roland in 1499 .
the world literature describes only a little more than 300 cases of pulmonary hernia .
pulmonary hernia is defi... |
the history of tobacco use in india can be traced back to almost 400 years .
the etiologic role of gutkha , a prepackaged mixture of areca nut , tobacco , slaked lime and flavoring agents in oral precancer and cancer is well documented.1 currently , available nicotine replacement therapy ( nrt ) products like chewing... | background : a pre - packaged mixture of areca nut , tobacco , slaked lime , catechu , and flavoring agents is popularly known as gutkha .
aim of study is to analyze the addiction biology of gutkha chewing and to assess efficacy of a cessation program based on nicotine replacement therapy ( nrt).materials and methods... |
there are reasonable indications that in children with asthma who are on long - term therapy of inhaled antiasthmatic drugs ( iad ) there is an increased risk of caries . in various studies that have investigated the impact of iad on oral health
has been demonstrated increased prevalence of caries in asthmatic compar... | introduction : the organism of children with asthma is exposed to the effects of the disease but also the drugs for its treatment .
antiasthmatic drugs have different modes that promote the caries formation which varies according to their basic pharmacological composition .
namely , these drugs have a relatively lo... |
a bone scan or bone scintigraphy is a nuclear scanning test to find certain abnormalities in bone that are triggering the bone 's attempts to heal . it is primarily used to help diagnose a number of conditions relating to bones , including : cancer of the bone or cancers that have spread ( metastasized ) to the bone , ... | the purpose of this study was to compare estimation of radiation absorbed doses to patients following bone scans with technetium-99m - labeled methylene diphosphonate ( mdp ) with the estimates given in mirdose software . in this study , each patient was injected 25 mci of 99mtc - mdp .
whole - body images from thirt... |
the expression " early childhood caries " ( ecc ) is used to refer to any stage of caries lesion in any surface of primary teeth of children up to 71 months of age7,11 .
the national survey carried out in 2002 - 20032 revealed a caries prevalence of 26.8% among 18 - 36-month - old brazilian children , and 23.2% among... | this study determined the prevalence of cavitated caries lesions ( ccl ) and early childhood caries ( ecc ) , and the contribution of some variables in children up to 36 months of age attending daycare centers in municipalities with different fluoride levels in the water supply : afc ( adequate fluoride content ) and l... |
alzheimer 's disease ( ad ) is the most common form of dementia ; it is the sixth leading cause of death in the united states .
more than 10% of americans over age 65 suffer from ad , and it is predicted that the prevalence of ad will triple within next 50 years [ 13 ] . currently , no known medicine exists for curin... | medical studies have shown that eeg of
alzheimer 's disease ( ad ) patients is slower
( i.e. , contains
more low - frequency power ) and is less complex compared to
age - matched healthy subjects .
the relation between those two
phenomena has not yet been studied , and they are often silently
assumed to ... |
from may 4 , 2009 , through october 31 , 2010 , participants received an automatically generated weekly email link to the online questionnaire , which asked whether they had experienced fever or cough and how many days they had been absent from work or normal duties because of these signs ( recruitment details in 2,3 ;... | we compared the accuracy of online data obtained from the flutracking surveillance system during pandemic ( h1n1 ) 2009 in australia with data from other influenza surveillance systems .
flutracking accurately identified peak influenza activity timing and community influenza - like illness activity and was significan... |
inflammation is one of the body innate immune responses and is mainly mediated by macrophages . when viruses or bacteria infect the body , significant cooperation among macrophages , dendritic cells , b cells , and t cells
various inflammatory molecules , such as cytokines ( e.g. , tumor - necrosis - factor- ( tnf- )... | nanostructured , self - assembling peptides hold promise for a variety of regenerative medical applications such as 3d cell culture systems , accelerated wound healing , and nerve repair .
the aim of this study was to determine whether the self - assembling peptide k5 can be applied as a carrier of anti - inflammator... |
silicon plays an important role in applications such as semiconductor devices , sensors , mechanical elements , and electronics .
mechanical properties of si , however , became a research focus only in the past few years owing to the development of the silicon on insulator ( soi ) technology and microelectromechanica... | this work presents the molecular dynamics approach toward mechanical deformation and phase transformation mechanisms of monocrystalline si(100 ) subjected to nanoindentation .
we demonstrate phase distributions during loading and unloading stages of both spherical and berkovich nanoindentations . by searching the pre... |
cyclophosphamide - based chemotherapy is a well - known agent triggering second malignancies in many patients .
similarly , radiation - induced cancers , mainly sarcomas are commonly seen at sites that have been included in radiation fields .
studies have shown a definite association between treatment for lymphoma ... | the treatment of lymphomas may result in the development of second malignancies , as evident by the numerous reports in the literature .
treatment with cyclophosphamide - based chemotherapy regimens may lead to bladder lesions such as haemorrhagic cystitis and also to carcinoma of the urinary bladder .
previous pel... |
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