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the relation between orthodontic force application and dental pulp tissue has been the subject of studies in the recent years . however , there is no conclusive evidence on the effect of orthodontic forces on pulpal tissue , and therefore , the issue has been studied for many years in human . reported that light cont...
background : there is no conclusive evidence on the effect of orthodontic force application on dental pulp tissue . the aim of this study was to compare early and delayed histological effects of intrusive forces on dental pulp of adolescents and adults.materials and methods : patients referred to the department of or...
pediatric deformity correction has been at the core of the foundation of orthopedics since the publication of lorthopedia by andry in 1741 . identifying these pathologic deformities and their subsequent management forms an integral part of pediatric orthopedic surgery . presence of angular deformities around the kn...
background : guided growth through temporary hemiepiphysiodesis has gained acceptance as the preferred primary treatment in treating pediatric lower limb deformities as it is minimally invasive with a lesser morbidity than the traditional osteotomy . the tension band plate is the most recent development in implants use...
dilated cardiomyopathy is an important cause of chronic congestive cardiac failure in infants and children . although a variety of etiological factors have been listed , most patients with echocardiographically documented dilated cardiomyopathy do not possess a demonstrable cause . poor myocardial function in dilated...
dilated cardiomyopathy is an important cause of congestive cardiac failure in infants and children . mobilizing hematopoietic progenitor cells is a promising intervention to this deadly disease . aim . evaluate granulocyte colony stimulating factor ( gcsf ) as therapeutic modality in children with idiopathic dilated ...
twenty - eight eyes of 28 glaucomatous subjects and 25 eyes of 25 normal healthy subjects were enrolled in this prospective study . this study was approved by the institutional review board of the asan medical center , and adhered to the tenets of the declaration of helsinki , with informed consent obtained from the ...
purposeto evaluate the structure - function relationships between retinal sensitivity measured by humphrey visual field analyzer ( hvfa ) and the retinal nerve fiber layer ( rnfl ) thickness measured by scanning laser polarimetry ( slp ) with variable corneal compensation ( vcc ) and enhanced corneal compensation ( ecc...
the diagnostic archives from the royal brompton and harefield nhs foundation trust and royal marsden hospitals from 2007 onwards were reviewed to identify cases with a diagnosis of lung adenocarcinoma that tested positive for an alk rearrangement ( > 15% positive cells ) , and a randomly selected complementary group of...
introduction : detection of the alk rearrangement in a solid tumor gives these patients the option of crizotinib as an oral form of anticancer treatment . the current test of choice is fluorescence in situ hybridization ( fish ) , but various cheaper and more convenient immunohistochemical ( ihc ) assays have been pr...
chronic myeloid leukemia ( cml ) is a myeloproliferative neoplasm characterized clinically by three distinct phases , ie , chronic , accelerated , and blastic , and occurs in 1.01.5 per 100,000 people each year in western countries.1 of note , cml is the prototype genetic cancer , presenting with the philadelphia chrom...
the therapeutic landscape of chronic myeloid leukemia ( cml ) has changed dramatically in the last decade . in particular , the availability of imatinib mesylate , a tyrosine kinase inhibitor targeting bcr - abl , has led to profound and durable remissions in the majority of patients . however , a couple of issues ha...
there are many reasons why it is important to be able to assess and compare hospitals in terms of quality and safety both within and between countries , for example to help hospitals improve their services and for governments to understand the impact of their policies . as it becomes more common for patients to seek he...
purposebeing able to compare hospitals in terms of quality and safety between countries is important for a number of reasons . for example , the 2011 european union directive on patients ' rights to cross - border health care places a requirement on all member states to provide patients with comparable information on...
amelogenesis imperfecta ( ai ) is a group of hereditary conditions that primarily affect the quality and/or the quantity of dental enamel , with a variable occurrence of approximately 1/700 - 1/14,000 . currently , mutations in six genes are known to have causal roles in the genetic etiology of ai : amelogenin , enam...
the aim of this clinical case series is to present a diagnosis and different treatment methods of patients in different ages with amelogenesis imperfecta ( ai ) as well as further treatments during a 3 - 6 years follow - up period . a number of 31 patients ( 16 female , 15 male with a mean age of 10.77 2.65 years ) ...
coronary artery disease ( cad ) is the number one killer in the world . as a case in point , each year 650,000 previously asymptomatic patients present in the united states with an acute coronary event as the initial presentation of cad.1 approximately , one - third of individuals dying annually from sudden cardiac dea...
background : more diagnostic techniques require a better understanding of the forces and stresses developed in the wall of the left ventricle . the aim of this study was to differentiate significant coronary artery disease ( cad ) patients using a non - invasive quantification of myocardial wall stress in the diastol...
the draft genome sequences of the brucella abortus strains lmn1 and lmn2 have been deposited in ddbj / embl / genbank under the accession numbers jphm00000000 and jphl00000000 , respectively .
we report the draft genome sequences of two brucella abortus strains lmn1 and lmn2 isolated from cattle and pig . the lmn1 and lmn2 have the genome size of 3,395,952 bp and 3,334,792 bp , respectively . in addition to the conserved genes of brucella , few novel regions showing similarity to the phages were identifi...
the prevalence of chronic obstructive pulmonary disease ( copd ) in women is increasing and , probably due to the changing patterns of tobacco smoking , to date it is almost equal compared to that in men ( gold , 2017 ) . consequently , also the current relative risk of mortality for copd is similar in men and women ...
the post - hoc analysis of the data collected from the lung health study supports the evolving concept that the impact of copd may be different between men and women , and supports the hypothesis of a gender - related responsiveness to the pharmacological treatment of copd . specific translational studies are needed ...
severe sepsis is one of the leading causes of morbidity and high mortality in intensive care units ( icus ) . septic patients had more severe organ dysfunction , longer intensive care unit and hospital lengths of stay , and higher mortality rate than patients without sepsis . there was a significant increase in icu m...
background : severe sepsis leads to organ failure and results in high mortality . organ dysfunction is an independent prognostic factor for intensive care unit ( icu ) mortality . the objective of the present study was to determine the effect of acute organ dysfunction for icu mortality in patients with severe seps...
in the immediate future it is recommended that radiology researchers should maintain individual responsibility for their career path , but this should be actively facilitated by their peer group . a research career should be encouraged to commence during residency and include an increased proportion of wet laboratory...
objectivesthe purpose of this investigation was to assess the current status of education in research in europe with a view to making recommendations and improvements in the status of education in research for involved stakeholders.methodsa questionnaire concerning education in research in europe was sent to the nation...
the first survey , intended to clarify the rift valley fever epidemiologic situation on the island , was undertaken in the mtsangamouji area ( northern part of mayotte ) . it examined samples from 29 illegally introduced goats and 79 cattle born on the island and living near the goats . among the 29 goats , competiti...
rift valley fever threatens human and animal health . after a human case was confirmed in comoros in 2007 , 4 serosurveys among ruminants in mayotte suggested that rift valley fever virus had been circulating at low levels since 2004 , although no clinical cases occurred in animals . entomologic and ecologic studie...
aspirin resistance is a documented unfavorable factor for patients undergoing percutaneous coronary interventions or coronary revascularization , while the impact of resistance to heparin is unclear . heparin resistance is reported in up to 22% of patients undergoing cardiopulmonary bypass [ 35 ] . it is usually ...
summarybackgroundheparin resistance is relatively frequent in patients undergoing coronary surgery . we aimed to assess the impact of heparin resistance on the outcome of patients undergoing coronary surgery with cardiopulmonary bypass ( cabg ) . three definitions of heparin resistance were adopted.material/methodswe...
in this issue of critical care , shorr and colleagues tested the potential value of surrogate markers for the treatment of patients with severe sepsis with activated protein c , also known as drotrecogin alfa ( activated ; drotaa ) , using data from the prowess ( recombinant human activated protein c worldwide evalua...
identification of good surrogate end - points can greatly facilitate the design of clinical trials . using data from prowess and enhance , shorr and colleagues explore the potential value of several plasma biomarkers for treatment trials of activated protein c for severe sepsis . based on the framework proposed by ...
coronary artery disease ( cad ) is the most common cause of death in the western world . the treatment of cad depends on the clinical picture , the results of provocative ischemia tests , the coronary lesions ( degree , location and anatomy ) , the left ventricular function , and associated co - morbidities . coron...
summarybackgroundto evaluate clinical and laboratorial parameters that predict decreased respiratory function in patients subjected to coronary artery bypass graft surgery ( cabg).material / methodsthis was a prospective study evaluating 61 patients subjected to cabg with cardiopulmonary bypass , median sternotomy , an...
drug resistance is the most relevant clinical problem in the management of solid malignancies . in many cases , after an initial response to treatment , cancer cells develop a resistant phenotype which is ultimately responsible for the fatal progression of the disease . mechanisms that induce drug resistance ...
class iii -tubulin plays a prominent role in the development of drug resistance to paclitaxel by allowing the incorporation of the gbp1 gtpase into microtubules . once in the cytoskeleton , gbp1 binds to prosurvival kinases such as pim1 and initiates a signaling pathway that induces resistance to paclitaxel...
aquired progressive kinking of the hair ( apkh ) and whisker hair are relatively rare conditions . to our knowledge , this blond , 23-year - old man referred that the hair around his ears and occipital area had turned darker , shorter , and curlier during the last 3 years . he also mentioned that the hair in that a...
acquired progressive kinking of the hair ( apkh ) and whisker hair are relatively rare conditions . to our knowledge , fewer than 25 cases have been reported in the english literature . we present the case of a 23-year - old man whose hair on the parietal and occipital areas changed and turned curlier and shorter ....
chronic low back pain ( lbp ) is considered to be a recurring human disease . in order to walk upright and hold their position , lbp is a multifactorial disease and it ca nt be managed by a simple treatment2 . various factors affect the stabilization of the muscles which can protect the spine joints , such as...
[ purpose ] the primary purpose of this study was to evaluate chronic low back pain by determining the ratio of the cross - sectional areas of the lumbar multifidus of the unaffected and affected sides at the l5 level using the ultrasound imaging . [ subjects and methods ] the subjects were 24 young people ( 10...
ultrasonography ( usg ) is a valuable method for imaging peripheral nerves , complementing routinelyperformed diagnostic studies , including the physical examination , electromyography and magnetic resonance imaging . in certain situations , usg becomes the imaging method of choice ; these include evaluating nerves o...
ultrasonography is an established method for imaging peripheral nerves . it serves to supplement the physical examination , electromyography , and magnetic resonance imaging . it enables the identification of post - traumatic changes of nerves , neuropathies secondary to compression syndromes , inflammatory or neop...
now the time has come to allocate resources and permit national planning to quantify the prevalence of diabetes mellitus and the number of people affected by diabetes , now and in the future . population growth , aging , urbanization , low physical activity and obesity are main causative factors of high prevalence of...
background and introduction : diabetes is increasing at alarming rate among indians especially south indians with prevalence of diabetes mellitus ( podm ) varying in populations of different regions . this study assesses podm in three geographical areas , namely : tribal , semi - urban , and urban , and to compare th...
smoking is a public health problem worldwide , having negative consequences and unfavorable economic implications , as well as being the leading cause of preventable death . 1 3 exposure to tobacco smoke is a major risk factor for various conditions that predispose to fatal noncommunicable diseases , 4 espe...
among all causes of preventable deaths , smoking is responsible for the greatest number of deaths worldwide and predisposes to fatal , noncommunicable diseases , especially cardiovascular diseases . lifestyle changes are effective in the treatment of patients with smoking - related diseases and assist in the preventi...
all humans have an identity in life ; compassionate societies require this identity to be recognized even after death . sex assessment of skeletal remains is an important step in building the biological profile of unidentified skeletons and it is widely agreed that the skull and pelvis are the most useful skeletal re...
background : all humans have an identity in life ; compassionate societies require this identity to be recognized even after death.objectives:to measure the dimensions of the mandibular canine and assess the usefulness of the mandibular canine as an aid in gender estimation.materials and methods : the study population ...
1 . the p53 is a tumor - suppressor gene and its mutation has been implicated in the genesis of skin cancers . the expression of proliferation marker , ki67 , is also increased in sundamaged skin . basal cell carcinoma ( bcc ) although rarely metastatic , it is capable of significant local destruction and disfigure...
background and aims : the cellular mechanisms responsible for initiating or limiting the tumors including skin types are of great importance . the p53 is a tumor - inhibiting gene which is believed to be defective in many malignant situations . ki67 is a non - histonic protein which is mainly interfere with the pro...
pulmonary sequestration refers to malformation of the primitive embryonic nonfunctional cystic lung tissue that is supplied by aberrant systemic artery and not connected to the normal tracheobronchial tree . selective angiography or computed tomographic angiography reveals the anomalous arterial supply and venous dra...
pulmonary sequestration is an embryonic , cystic lung tissue that is supplied by systemic blood circulation . it is a nonfunctional lung parenchyma unconnected to normal tracheobronchial system . in cases of pulmonary sequestration , surgical interventions should be performed in order to prevent possible complicati...
computed tomography ( ct ) and magnetic resonance imaging ( mri ) have been widely used for patients with acute neurological manifestations . however , these imaging techniques at times may be misleading , especially in a busy emergency room ( er ) where doctors may have limited time to evaluate the patients thorough...
we report on an 81-year - old man who presented with left limbs weakness and was brought to the emergency room where a brain computed tomography revealed a tumor at the right parasellar region . the patient was admitted to the neurosurgery department , and the symptoms were thought to be due to the tumor mass effect ...
currently , cancer treatments are increasingly more effective , although they have been associated with short and long term oral side effects such as oral candidiasis and oral mucositis . regarding esophageal cancer , it has been reported that the most frequent problems associated with esophageal surgery were related...
objective : during the perioperative period , oral ingestion is changed considerably in esophagectomy patients . the aim of this study was to investigate oral environment modifications in patients undergoing esophageal cancer treatments due to changes in dietary intake and swallowing functions.material and methods : ...
the bottlenose dolphin ( tursiops truncatus ) is a marine mammal positioned at the top of the food chain . the dolphins are organized into highly structured communities known as groups , in which the sex and age of members in the community are balanced to fulfill the functions of the group , such as the feeding syste...
in order to obtain information regarding the correlation between an electroencephalogram ( eeg ) and the state of a dolphin , we developed a noninvasive recording method of eeg of a bottlenose dolphin ( tursiops truncatus ) and an extraction method of true - eeg ( eeg ) from recorded - eeg ( r - eeg ) based on a human ...
the demand for esthetic restorations in dentistry has increased over the past few years . since resin composites were first developed , many efforts have been made to improve the clinical behavior of these restorative materials . although both organic and inorganic phases might influence the material behavior , the f...
background : adequate polymerization of resin composites could be considered as a crucial factor in obtaining good clinical performance , particularly in stress - bearing areas . an insufficient curing degree affects the resin composite 's chemical properties the current in vitro study evaluated the influence of poly...
the unique physical properties attributed to nanoscale materials have led to a rise of nanomaterials research in recent years . for example , nanopatterned magnetic structures have been studied for applications as varied as high - density data storage to biomedical sensing . additionally , plasmonic nanomater...
large area arrays of magnetic , semiconducting , and insulating nanorings were created by coupling colloidal lithography with nanoscale electrodeposition . this versatile nanoscale fabrication process allows for the independent tuning of the spacing , diameter , and width of the nanorings with typical values ...
periosteal osteosarcoma ( perosa ) is an intermediate - grade malignancy arising on the surface of bones , frequently in femur and tibia , followed by ulna and humerus in extremities ( 1 , 2 ) . perosa of the chest wall , unlike that of the extremities , presents a diagnostic challenge because of the extreme rarity o...
periosteal osteosarcoma is an extremely rare chondroblastic osteosarcoma in the flat bone . there were authors reporting of two cases of periosteal osteosarcoma in the highly unusual sites . one of them arose from the rib , in a 17-year - old male , which appeared as a hypodense juxtacortical mass with periosteal r...
despite being a relatively rare type of cancer , pancreatic cancer is ranked as the 8 and 9 leading cause of death in men and women , respectively . thus , this cancer is , usually , diagnosed when in the advanced stages ; therefore , the curative treatment is ineffective . commonly used noninvasive imaging modalit...
background and objectives : most of the available data on pancreatic cancer are from western countries . the aim was to characterize pancreatic cancer in asian patients and to compare it with pancreatic cancer in caucasians.materials and methods : inpatients with histologically proven pancreatic cancer were retrospecti...
it is a most unwelcome experience and challenge for an anesthesiologist to find a potentially difficult airway at the end of procedure . the main concerns in palatoplasty , at the time of extubation are hemorrhage and upper airway obstruction . it is well - known that patients with franceschetti syndrome and pierre...
we report two cases of massive tongue edema in routine palatoplasty . all patients had uneventful recovery . we postulated that the macroglossia was secondary to ischemia and venous congestion after prolonged use of killner dott mouth gag with slotted tongue blade exaggerated by hyperextension of neck and trendelen...
the story of cytoplasmic protein lysine acetylation begins long after the discovery of posttranslational acetylation of histones in the sixties . in fact only in 1985 tubulin was described as the first acetylated cytoplasmic protein [ 2 , 3 ] . since then the first global proteomic study on acetylated proteins desc...
reversible posttranslational modification of internal lysines in many cellular or viral proteins is now emerging as part of critical signalling processes controlling a variety of cellular functions beyond chromatin and transcription . this paper aims at demonstrating the role of lysine acetylation in the cytoplasm dr...
the cause of postoperative endophthalmitis after ocular surgery is not known , and is probably variable . good et al suggested that partial obstruction of the nasolacrimal duct and upper airway infection could be the risk factors for development of postoperative endophthalmitis in children undergoing cataract surgery...
abstractbackground : the incidence of nasal secretions into the operative field is as high as 5% in ophthalmic surgery under general anesthesia . it may induce postoperative endophthalmitis . secretions under propofol - based total intravanous anesthesia ( tiva ) are greater than sevoflurane anesthesia during surge...
the increasing prevalence of mobility limitations among seniors is a concern , as it affects the quality of life of the elderly population ( yong et al . , 2010 ) . it has far - reaching consequences , because older individuals who are less mobile are also likely to suffer from poorer health , depression , and social...
singapore s life expectancy at birth and at age 65 continues to improve . although this is a positive development , it is necessary to understand how much of this increased life expectancy is spent with and without mobility limitations . this research uses the latest round of the national survey of senior citizens ...
case 1 : a 49-year - old man with neovascular glaucoma ( nvg ) in the right eye ( re ) , who had undergone phacoemulsification , posterior chamber lens ( pcl ) implantation , and agv implantation , was referred to us . his intraocular pressure ( iop ) ( re ) was 40 mmhg despite medical therapy including dorzolamide 2...
we report four cases in which a pericardium ( tutoplast ) plug was used to repair a corneoscleral fistula after ahmed glaucoma valve ( agv ) explantation . in four cases in which the agv tube had been exposed , agv explantation was performed using a pericardium ( tutoplast ) plug to seal the defect previously occupie...
using in vitro production of embryos allows us to obtain a large number of offsprings from live or slaughtered animals ( 1 ) for research , genetic improvement or commercial purposes ( 2 ) . in sheep , techniques for in vitro fertilization and in vitro culture of embryos ( ivc ) seems to be under control . however in...
background : improvements in culture media formulations have led to an increase in the ability of sheep embryo in culture throughout the preimplantation period . objective : this study was carried out to evaluate the effects of various concentrations of mem vitamins during in vitro maturation of sheep oocytes and sub...
reaching social stable development , as a whole , requires the cooperation of all members of a community . providing and improving health standard is one of the financial dimensions of human social evolution , which , more than the other aspects of development , demands public cooperation . for health approach provid...
background : to achieve stable social development , the cooperation of all members of a -community is basically required . providing and improving the health standard is one of the most fundamental dimensions of human social evolution . this is more essential than the other aspects of development ( public cooperati...
cryptosporidium species are apicomplexan protozoa that infect humans and a wide variety of vertebrate animals . cryptosporidiosis is a self - limiting disease of intestinal tract in immune - competent individuals and a severe chronic disease in immunocompromised patients . cryptosporidiosis has been considered to b...
objectives . the prevalence of cryptosporidium and the risk factors of zoonotic transmission in najafabad , isfahan , iran dairy farms were examined . methods . one fecal sample was collected from all calves less than 6 months old in eight dairy farms around najafabad ( isfahan province , central iran ) as well as in...
an orphan is defined as a child under 18 years who has lost his father , mother or both parents . orphans , therefore , are considered disadvantaged and socially marginalized population whom diseases burden is high . poor living conditions in orphanages where children live might be related to many complex health pr...
objectives : the aim of this study was to assess the prevalence of oral mucosal lesions ( omls ) and dental caries and to evaluate oral health practices among institutionalized orphan - children in sanaa city , yemen.subjects and methods : a sample of 202 institutionalized male - orphan - children in the main orphanage...
this was a retrospective observational study conducted at shree krishna hospital , which is a 550 bedded multi speciality and tertiary care teaching rural hospital . from july 2009 to november 2009 , all hospitalized patients were screened from the system department of our hospital based on the serum creatinine ( scr...
aim : study was aimed to assess the accuracy of drug dose and its frequency in patients with renal dysfunction in a tertiary care hospital.materials and methods : this was a retrospective observational study . patients > 18 years old , with the serum creatinine ( scr ) level > 1.4 mg / dl were included . drugs pres...
insulin - like growth factor-1 ( igf-1 ) is an important regulator of cell proliferation , differentiation , and apoptosis , has acute insulin - like metabolic effects , and is important for growth and development throughout the body . the level of igf-1 peaks during puberty and after which it declines with age . alt...
several studies have demonstrated an association between polymorphisms in the insulin - like growth factor-1 ( igf-1 ) gene and igf-1 serum levels . igf-1 levels have been associated with cognitive functioning in older persons and growth hormone deficient patients . the present study investigates whether igf-1 poly...
sepsis is defined as life - threatening organ dysfunction due to a dysregulated host response to infection , which is still a leading cause of deaths in the critical illness . neutrophils are the most abundant of all white blood cells in the human circulation and play a key role in host protection against microbial i...
objective : sepsis is defined as life - threatening organ dysfunction due to a dysregulated host response to infection . in this article , we reviewed the correlation between neutrophil dysfunction and sepsis.data sources : articles published up to may 31 , 2016 , were selected from the pubmed databases , with the keyw...
estrogens are known carcinogens recognized as prime risk factor for the development of breast cancer . the principal enzyme controlling estrogen metabolism in breast tissue is cytochrome p450 1b1 ( cyp1b1 ) , which sequentially oxidizes e2 to 4-ohe2 and the estrogen quinone ( e2 - 3,4-q , figure 1 ) . the highly re...
in cells , dna repair has to keep up with dna damage to maintain the integrity of the genome and prevent mutagenesis and carcinogenesis . while the importance of both dna damage and repair is clear , the impact of imbalances between both processes has not been studied . in this paper , we created a combined mathe...
this syndrome constitutes a variable combination of menstrual irregularity , hirsutism , acne , and obesity . women with this condition are known to have an average of about five visits to different consultants before actual diagnosis . they would have consulted a gynecologist for menstrual irregularity and inferti...
introduction : polycystic ovarian syndrome ( pcos ) constitutes most cases of endocrine disorder among females.objectives:this study was done to assess the proportion of university students with pcos and to study its risk factors.materials and methods : data were collected from students of a private medical , dental , ...
the intraoperative contamination of a bone fragment during any orthopaedic surgery such as dropping the specimen on the floor could occasionally occur and create a serious dilemma for the surgeon . if the autograft is contaminated this way on the operating room floor during the surgery , salvage can be done by differen...
backgroundto determine the efficacy of three different antiseptic solutions ( control group ( i ) , antibiotic solution neomycin and polymyxin ( ii ) , chlorhexidine 0.4% ( iii ) , and povidone iodine 10% ( iv ) ) in disinfecting contaminated bone fragments.methodsunder sterile conditions , the femora of 12 rabbits ...
a pain drawing ( pd ) is a simple line drawing of the human body ( front and back)1 on which patients can indicate their pain for both clinical and research purposes2 . pds may differ from each other depending on whether the image is simple3 or detailed4 , 5 , presents a frontal or sagittal perspective , or depic...
the aim of this systematic review and meta - analysis was to estimate the accuracy of qualitative pain drawings ( pds ) in identifying psychological distress in subacute and chronic low back pain ( lbp ) patients . [ subjects and methods ] data were obtained from searches of pubmed , ebsco , scopus , psycinfo a...
a 41-year - old man was admitted to the emergency room due to a sudden onset of chest pain radiating to the back and dyspnea . upon reaching the hospital , the patient was in hemodynamically stable condition except for mild elevation of his respiration rate ; his blood pressure was 130/90 mmhg , pulse rate was 84 beats...
a bronchial artery aneurysm ( baa ) is uncommon and usually associated with chronic inflammatory lung disease or a systemic vascular condition , which is rarely the etiology of mediastinal hemorrhage . a middle - aged person presented with spontaneous hemothorax and hemomediastinum . a diagnostic evaluation identifie...
the first screening method of screening for trisomy 21 was based on the maternal age . since the late 1980s , a test was universalized for three fetoplacental products ( alpha - fetoprotein , unconjugate estriol , and total hcg ) in the maternal serum at the second trimester of gestation . in addition , various sonog...
this study evaluated the sensitivities and false positive rates of the screening test using ultrasonographic measurement of thickness of nuchal translucency ( nt ) with different cut - offs for chromosomal aberration in a korean population . we included 2,570 singleton pregnancies undergoing ultrasound between 11 wee...
diabetic nephropathy ( dn ) is the most common cause of end - stage renal disease ( esrd ) ( 1 - 3 ) . patients with non - insulin - dependent diabetes mellitus ( niddm ) present a high risk for developing severe complications , such as dn , retinopathy and cardiovascular disease . studies demonstrating familial cl...
background : angiotensin - converting enzyme ( ace ) insertion / deletion ( i / d ) and vascular endothelial growth factor ( vegf ) polymorphisms have been shown to associate with diabetic nephropathy ( dn).objectives : we examined the hypothesis that ace - d and vegf - g alleles act synergistically in association with...
diagnosis of these patients relies on accurately measuring the levels of growth hormone in the blood and changes therein using a provocation test . however , values obtained using the different kits available in japan have always differed considerably , to an extent that could affect a proper clinical judgment ...
accurate and reliable determination of blood growth hormone level is essential in the diagnosis and treatment of short stature children . however , measured levels differed considerably among measurement kits available in japan until 2003 . therefore , standardization of the measured values was attempted by m...
maternally transmitted bacteria of the genus wolbachia form a monophyletic clade of intracellular alpha - proteobacteria and are particularly related to the rickettsia that cause human diseases such as rocky mountain spotted fever , typhus and q - fever ( hackstadt , 1996 ) . wolbachia have been reported to have nega...
the uzifly , exorista sorbillans ( diptera : tachinidae ) , a parasitoid of the silkworm , bombyx mori l. ( lepidoptera : bombycidae ) , harbours wolbachia ( rickettsia ) endosymbionts . administration of 0.05 mg / ml oxytetracycline to the adult uziflies removed wolbachia endosymbionts and resulted in different repr...
during the outbreak period , ptwrc housed 6001,000 wild animals ( 70 species of mammals , birds , and reptiles ) . the center is divided into 3 main sections that cover 37 ha . birds were kept in sections s11 , s12 , and s2 , and the cats were in all sections ( figure ) . the information on bird deaths at ptwrc was...
from december 2003 through january 2004 , the phnom tamao wildlife rescue centre , cambodia , was affected by the highly pathogenic influenza virus ( h5n1 ) . birds from 26 species died . influenza virus subtype h5n1 was detected in 6 of 7 species tested . cats from 5 of 7 species were probably infected ; none di...
persistent mllerian duct syndrome ( pmds ) is a rare genetic disorder representing male pseudo - hermaphroditism . it is a sex - limited autosomal recessive disorder where a male ( 46 chromosomes ; xy ) with normal external reproductive organs is characterized by the presence of female reproductive organs , namely , ...
persistent mllerian duct syndrome ( pmds ) is a rare , sex - limited , autosomal recessive disorder representing male pseudo - hermaphroditism . it is observed in males with the presence of female reproductive organs such as the uterus , cervix , and bilateral fallopian tubes along with normally developed male reproduc...
many diverse lines of evidence indicate that schizophrenia is a neurodevelopment disorder ; early - life adverse events such as prenatal stress , obstetric complications , malnutrition , and viral infection may interrupt the normal brain development and increase the susceptibility of schizophrenia later in life [ 1...
neonatal blockade of n - methyl - d - aspartic acid ( nmda ) receptors represents one of experimental animal models for schizophrenia . this study is to investigate the long - term brain - derived neurotrophic factor ( bdnf ) expression profiles in different regions and correlation with schizophrenia - like behavi...
percutaneous vertebroplasty ( pvp ) is a minimally invasive interventional procedure in which bone cement is injected into a fractured vertebra to treat painful vertebral compression fractures ( vcfs ) during the last two decades.123 pvp has numerous advantages , including quickly relieving pain , improving a quality o...
background : percutaneous vertebroplasty ( pvp ) is now widely performed to treat painful vertebral compression fractures . previous researches have reported numerous advantages . however , it rarely reported that how to determine the feasibility of the unilateral or bilateral approach and how to decide the punctur...
relational aggression , rumor spreading , backstabbing , and social isolation , is recognized as a violent act and is no longer considered a normal part of growing up . research has indicated the experience of peer ( girl - girl ) relational aggression whether from the standpoint of the perpetrator or the victim as...
purpose . relational aggression , rumor spreading , backstabbing , and social isolation , is psychologically damaging for adolescent girls . the purpose of this study was to provide an explanation of victimization response after experiencing peer relational aggression victimization . methods . grounded theory tec...
major depression is a severe psychiatric disorder with a lifetime prevalence in excess of 15%,1 and is the fourth leading cause of disability worldwide . the world health organization estimates that depression causes 6% of the burden of all diseases in europe in terms of disability - adjusted life years . full remi...
backgroundthe purpose of this study was to evaluate the long - term effect of repetitive transcranial magnetic stimulation ( rtms ) as adjunctive treatment in patients with partial remission of major depressive disorder.methodsthis was a 12-month , prospective , open - label study in patients meeting the diagnostic and...
what des - cartes did was a good step . you have added much several ways . . . the scientific research community depends on open knowledge sharing to increase the speed and effectiveness of scientific research , yet current publishing models reduce both the speed and efficiency of knowledge dissemination . the scie...
the national institutes of health ( nih ) are responsible for the largest proportion of biological science funding in the united states . to protect the public interest in access to publicly funded scientific research , the nih amended terms and conditions in funding agreements after 2009 , requiring funded principal i...
granular cell tumor ( gct ) is an uncommon benign tumor , affecting the skin and internal organs . the tumor is usually asymptomatic although some patients may experience mild pruritus or pain . a case of a large solitary painful gct a 48-year - old housewife presented to us with a painful solid mass over her upper...
granular cell tumor is a distinctly rare neoplasm of neural sheath origin . it mainly presents as a solitary asymptomatic swelling in the oral cavity , skin , and rarely internal organs in the middle age . histopathology is characteristic , showing polyhedral cells containing numerous fine eosinophilic granules wit...
despite the latest advances in anesthesia and the introduction of a new class of antiemetics , postoperative nausea and vomiting ( ponv ) is still one of the most common postoperative patient complaints . generally , one - third of patients undergoing surgery are known to suffer from postoperative nausea , vomiting ,...
it was previously reported that the korean predictive model could be used to identify patients at high risk of postoperative nausea and vomiting ( ponv ) . this study investigated whether ponv in the high - risk and very high - risk patients identified by the korean predictive model could be prevented by multiple pro...
trypanosomosis is a widely spread protozoan disease complex which affects cattle and other wide range of hosts in sub - saharan africa . the course of the disease may run from a chronic long lasting to an acute and rapidly fatal depending on the vector - parasite - host interactions . the disease is mainly characte...
cross - sectional study was conducted in dale wabera district of kellem wollega zone , western ethiopia , to determine the prevalence of bovine trypanosomosis and to evaluate association of bovine trypanosomosis to anaemia . blood samples collected from 384 randomly selected cattle were subjected to parasitological a...
studies on rodent parasites of medical and veterinary importance have been performed to prevent transmission of diseases to humans and domestic animals . the striped field mouse , apodemus agrarius , is the most dominant species and the agricultural scourge in the republic of korea ( = korea ) . this mouse species ...
the present study was performed to know the infection status of intestinal helminths in a most common species of field mice , apodemus agrarius , from 2 southern regions of korea . total 133 and 103 mice were collected by the mouse trap in hapcheon - gun , gyeongsangnam - do and gurye - gun , jeollanam - do , respect...
a flexible flat foot refers to a structural deformity in which the medial longitudinal foot arch has become abnormally depressed under weight - bearing conditions1 , 2 . due to the flat foot , the loading on the foot can not be properly distributed , and more activities of the intrinsic and extrinsic muscles ar...
[ purpose ] the aim of this study was to examine differences in the muscle tone and stiffness of leg muscles according to types of flexible flat foot . [ subjects and methods ] for 30 subjects 10 in a normal foot group ( nfg ) , 10 in group with both flexible flat feet ( bffg ) , and 10 in a group with flexible f...
maybe the most important step forward in cardiology care is the early treatment of acute ischaemia of the heart . by performing immediate angiography in patients with the clinical presentation of an acute coronary syndrome ( acs ) , and more specifically when there are signs of st elevation on the 12-lead ecg ( st - se...
stemi time delays have been introduced as a performance indicator or marker of quality of care . as they are only one part of a very complex medical process , one should be aware of concomitant issues that may be overlooked or even be more important with regard to clinical outcome of stemi patients . in this overview...
bovine viral diarrhea ( bvd ) is one of the most important cattle diseases characterized by diarrhea , abortion , stillbirth , return to estrus , and milk drop . economic impact of bvd has led a number of countries in europe to start eradication or control programs ( 1 , 2 ) . bvd is caused by bovine viral diarrhea v...
background : bovine viral diarrhea ( bvd ) is an economically important disease of cattle distributed worldwide . diagnosis of bvd relies on laboratory - based detection of its viral causing agent or virus specific antibodies and the most common laboratory method for this purpose is enzyme - linked immunosorbent assa...
overall mortality rate decreased , expectancy of life increased , a lot of new life saving drugs discovered which helps us to fight against several infectious and other diseases , and new advancement in the field of technology has boosted the capacity of modern science . in spite of such incredible advancement whether ...
in spite of incredible advances in modern science , technology and allopathic medicine a large we are unable to provide quality healthcare to all . traditional medicine particularly herbal medicine considered as a major healthcare provider around the globe particularly in rural and remote areas . a large section of...
the palatal groove is defined as a developmental groove in root , that when present is usually found on the palatal aspect of the maxillary incisor teeth . palato - radicular groove is a rare developmental anomaly with prevalence rate of 2.8 - 8.5% , mostly present on the lingual surface of the maxillary lateral inc...
this study is to report the rare localization of a radicular groove on the palatal aspect of the maxillary lateral incisor and to discuss the pathology and management of the concomitant endo - periodontal defect . unilateral palato - radicular groove was located on the maxillary right lateral incisor of an 18-year - ...
mucormycosis is an opportunistic infection of the human body , seen mainly in immunosuppressed states . renal involvement usually occurs in disseminated forms and is seen in up - to 19% of such cases . . however , majority of the patients ( 75% ) suffering from isolated renal mucormycosis in india are apparently he...
we report a case of isolated extensive renal mucormycosis in an immunocompetent adult , who was successfully managed conservatively without surgical debridement . to the best of our knowledge , this is the first case where antifungal therapy alone was sufficient even with such an extensive involvement .
chronic respiratory diseases represent a group of diseases characterized by abnormal condition of the respiratory system such as inflammation of the airways , airflow obstruction , chest pain , dyspnea , hemoptysis , and sputum production.1 globally , respiratory diseases remain the largest single contributor to the ov...
backgroundasthma , dyspnea , and chronic cough are well - established risk factors of copd and often associated with exacerbation of the disease , which is a leading cause of morbidity and mortality in south asian countries.objectivethe aims of this study were to , 1 ) measure the prevalence of asthma , dyspnea , and c...
obstructive sleep apnea ( osa ) is a sleep - disordered breathing with repeated upper airway obstruction during sleep due to the collapsing pharyngeal airway . the reported prevalence of osa is approximately 3 - 7% in men and 2 - 5% in women in the general population with a major risk factors , including male gender ...
background : obstructive sleep apnea ( osa ) is very frequent and often unrecognized in surgical patients . osa is associated with perioperative complications . we evaluated the effects of osa on postoperative complications and hospital outcomes in patients undergoing coronary artery bypass graft ( cabg ) surgery.m...
animals : we assessed 72 buffalo ( 43 females and 29 males ) aged between 3 and 36 months ( mean sd : 20 4 months ) , and weighing between 70 and 500 kg ( 350 50 , mean sd ) . animals were admitted to mansoura veterinary teaching hospital , egypt , between january 2013 and september 2015 . buffalo were in...
we studied 72 buffalo with superficial swellings in the head ( n=4 ) , neck ( n=5 ) , chest wall ( n=4 ) , abdominal wall ( n=28 ) , limbs ( n=16 ) , gluteal region ( n=8 ) , perineal region ( n=6 ) and udder ( n=1 ) . ultrasonographically , the swellings varied according to type , duration , content and locati...
until recently , the assessment of the endometrial - myometrial junctional zone ( emj ) was mainly used on magnetic resonance images ( mri ) for the diagnosis of adenomyosis ( hricak et al.,1983 ) . . however , on ultrasound the emj is not always easy to display and there are currently no strict guidelines on how to ...
objectives : the aim of this study was to find the best 3d reconstruction technique to visualize the endometrial - myometrial junction ( emj).methods : retrospective observational study on 240 stored 3d volumes of 80 patients . the first author reconstructed the 2d midcoronal image without volume contrast imaging ( v...
the thermally activated spin relaxation of ferromagnetic ( fm ) nanocrystals ( ncs ) continues to be of interest in applied physics because of its relevance to the design of magnetic storage media and spin transport devices [ 1 - 3 ] . according to the stoner wohlfarth model , rotation of the macrospin from one energ...
the thermal relaxation of macrospins in a strongly interacting thin film of spinel - phase iron oxide nanocrystals ( ncs ) is probed by vibrating sample magnetometry ( vsm ) . thin films are fabricated by depositing feo / fe3o4 core shell ncs by electrophoretic deposition ( epd ) , followed by sintering at 400c . ...
align and center the narrow end of the large reducer base on the camera hole of the smartphone cover . the area of contact of the reducer and cover is then carefully glued [ fig . 2 ] . the 50 mm pipe is used as the optical tube . a piece of sandpaper 17 cm 14.8 cm , is rolled and inserted into the tube and glued ...
this article describes the method to make a do it yourself smartphone - based fundus camera which can image the central retina as well as the peripheral retina up to the pars plana . it is a cost - effective alternative to the fundus camera .
the model of functional recovery surpasses the traditional medical model of symptomatic remission1 to include the realization of meaningful roles in the community . unfortunately , full functional recovery is rarely attained and even less frequently maintained , even after symptoms have remitted.2 profound impairment...
backgroundnew approaches to assess outcome in schizophrenia include multidimensional measures such as remission , cognition , psychosocial functioning , and quality of life . clinical and psychosocial measures have been recently introduced to assess functional outcome.objectivethe study presented here was designed to...
leiomyosarcoma ( lms ) is a malignant smooth muscle tumor , which is usually seen in the uterus and gastrointestinal tract . the proportion of malignancies among smooth muscle tumors of the oral cavity is disproportionately high in comparison with the low ratio of malignant to benign smooth muscle tumors in the femal...
leiomyosarcoma ( lms ) is a malignant soft tissue tumor that exhibits smoothmuscle differentiation . its occurrence in the oral cavity is exceedingly rare . this article presents a 67-year - old woman with 9-month history of a painful tumoral lesion on the right side of mandible . tumor was composed of fascicles ...
acute subdural hematoma ( sdh ) is a known complication of moderate to severe head injury . sudden onset of loss of consciousness or development of neurological deficit in an otherwise healthy person is usually secondary to any cerebrovascular event . aneurysm of internal carotid artery ( ica)-posterior communicati...
spontaneous pure acute subdural hematoma ( sdh ) is arguably a rare condition . we report on a pregnant female patient presenting as spontaneous acute sdh without subarachnoid hemorrhage ( sah ) due to rupture of distal ( m5 segment ) middle cerebral artery aneurysm . we hereby discuss the diagnostic dilemma of ...
most cases of anhidrotic ectodermal dysplasia are x - linked recessive type , accounting for 80% of cases . however there is a rare autosomal recessive variant of anhidrotic ectodermal dysplasia which can be clinically indistinguishable from xl - aed . ectodermal dysplasias ( ed ) are a heterogeneous group of disor...
we describe a case of anhidrotic ectodermal dysplasia ( aed ) with an autosomal recessive mode of inheritance , a very rare entity , in a 2-year - old female child of two asymptomatic , consanguineous parents . their previous child also had a similar condition . autosomal recessive aed ( ar - aed ) can have its ful...
malaria caused by plasmodium , particularly plasmodium falciparum , is the most serious and widespread parasitic disease of humans . each year approximately three hundred million people become infected with malaria and two to three million die as a result in the tropical and subtropical areas of the world . among the...
malaria is still a devastating disease caused by the mosquito - transmitted parasite plasmodium , particularly plasmodium falciparum . during the last few years the situation has worsened in many ways , mainly due to malarial parasites becoming increasingly resistant to several anti - malarial drugs . thus there is...
hypertriglyceridemia ( htg ) and alcoholism are among the most common causes of acute pancreatitis ( ap ) after gallstones . elevated triglyceride levels , especially > 1,000 mg / dl , are a well - recognized risk factor for the development of ap . animal studies have shown that infusion of triglycerides causes hyp...
background : alcohol and hypertriglyceridemia ( htg ) are among the most common causes of acute pancreatitis ( ap ) after gallstones . however , differences in severity at the time of presentation and outcomes have not been well-studied.objective:the aim of this study is to assess the differences between severity at ...
we demonstrate the evolution of the pylrs / trnacua pair for genetically encoding photocaged cysteine . by characterizing the incorporation in escherichia coli and mammalian cells , and the photodeprotection process in vitro and in mammalian cells , we establish conditions for rapid efficient photodeprotect...
it is well established that there is a strong correlation between the presence of eosinophils and the presence of th2 cells in the asthmatic airways and that classical th2 cell - derived cytokines , namely il-4 , il-5 , and il-13 , play critical roles in orchestrating and amplifying allergic inflammation in asthma . ...
asthma is characterized by chronic airway inflammation with intense eosinophil and lymphocyte infiltration , mucus hyperproduction , and airway hyperresponsiveness . accumulating evidence indicates that antigen - specific th2 cells and their cytokines such as il-4 , il-5 , and il-13 orchestrate these pathognomonic fe...
conformal radiotherapy ( crt ) is now the accepted standard for curative radiotherapy of many tumours . it offers the advantage of improved coverage of the tumour and high - risk areas , together with sparing of normal tissues , thereby improving the therapeutic ratio and allowing increased cure with fewer side effec...
the purpose of this study was to explore how radiologist and oncologists may work together efficiently and effectively to define target volume for radiotherapy treatment . ten patients were chosen at random from those needing radiotherapy between december 2004 and june 2005 . sites of primary cancer included head a...
percutaneous nephrolithotomy ( pcnl ) is a well - established and safe procedure for the management of renal stones [ 13 ] . the outcome of the procedure depends on a variety of factors , including operative technique , body mass index ( bmi ) , number of comorbidities , renal collecting system anatomy , initial ston...
backgroundit is unclear whether parenchymal thickness ( pt ) , in combination with stone density measured by hounsfield units ( hu ) , affects stone - free rates after pcnl . the aim of the present study was to investigate the relationship between pt in combination with stone density values and the outcomes of pcnl.m...
vitamin d3 supplementation reduced the risk of allcause and cancer mortality in a recent cochrane analysis . other extraskeletal effects of vitamin d deficiency or insufficiency are possible but not firmly established since the threshold of such effects may vary . several large observational studies linked low 25(o...
backgroundwe tested the controversial hypothesis that vitamin d depletion aggravates hypertension and targetorgan damage by influencing renin.methods and resultsfourweekold doubletransgenic rats ( dtgr ) with excess angiotensin ( ang ) ii production due to overexpression of the human renin ( hren ) and angiotensinogen ...
one of the leading causes of mortality and morbidity amongst pregnant women and their offspring is pre - eclampsia ( pe ) , affecting 2%8% of all pregnancies depending on the criteria of diagnosis and ethnic population . the symptoms manifest themselves in the late second or third trimester of pregnancy but there is ...
several studies point to the placenta as the primary cause of pre - eclampsia . our objective was to identify placental genes that may contribute to the development of pre - eclampsia . rna was purified from tissue biopsies from eleven pre - eclamptic placentas and eighteen normal controls . messenger rna express...
a 36-year - old healthy woman with reddish , painless local swellings over the dorsal aspect of the proximal interphalangeal ( pip ) joints of both hands presented at our rheumatologic outpatient clinic to exclude an inflammatory joint disease . she noticed the swellings over a period of one year without any trigger ...
knuckle pads are rare harmless subcutaneous nodules that must be differentiated from joint disease of the proximal interphalangeal or rarely of the metacarpophalangeal joints as well as from other masses of the paraarticular tissues . we present a case of an otherwise healthy 36-year - old woman presenting with bilat...
cytokines have essential roles in the development , differentiation , and function of the immune response . following receptor ligation cytokines , including interleukins ( ils ) , interferons ( ifns ) , and haematopoietic growth factors , activate the janus kinase - signal transducer and activator of transcription (...
the intracellular suppressors of cytokine signaling ( socs ) family members , including cish and socs1 to 7 in mammals , are important regulators of cytokine signaling pathways . so far , the orthologues of all the eight mammalian socs members have been identified in fish , with several of them having multiple copies...
thoracic aortic disruption most often results from a high - speed motor vehicle collision . a finding of left atrial dome disruption as the cause of cardiovascular collapse following blunt trauma is unusual . a 32-year - old man sustained multiple injuries following a high - speed dirt bike collision at 70 mph . on i...
left atrial ( la ) rupture is rare following blunt chest injury . we describe a case of blunt la rupture that was treated surgically . this report is intended to alert practitioners for a need of a close multiple disciplinary collaborations among them for optimal management of patients with this type of trauma ; beca...
for a given province , year , maternal age group , and the estimated number of live patients with congenital t. cruzi infection were computed as the total number of live newborns ( f ) , times the probability of a woman s being infected with t. cruzi ( p ) , times the probability of transmitting t. cruzi to the live ne...
trypanosoma cruzi , the causative agent of chagas disease , infects 1018 million people and may be transmitted to the newborn . using various data sources , we estimated that nearly 850 congenital cases occurred in argentina in 1993 , or 6.3 expected cases per each reported case in 1994 and in 19942001 . the congen...
enterovirus 71 ( ev71 ) is a positive - stranded rna genome and belongs to a member of the species a , enterovirus genus , picornaviridae family . ev71 is one of the major causative agents of hand , foot , and mouth disease ( hfmd ) in young children , which has caused a series of outbreaks of hfmd throughout the wor...
enterovirus 71 ( ev71 ) is a major causative agent of hand , foot , and mouth disease ( hfmd ) in children . the role of t follicular helper ( tfh ) cells in ev71-infected children remains unclear in regulating humoral immunity . the frequency of circulating icoshigh / pd-1highcxcr5+cd4 + tfh cells in the children ...
down syndrome ( ds ) was first described in 1866 by john langdon down and affects 1 in every 6001000 live births ; ds is the most common genetic cause of intellectual disabilities . trisomy of chromosome 21 is the most common cause for ds , accounting for approximately 95% of all ds cases . the life span of ds indi...
objective . to quantify the severity of malocclusion and dental esthetic problems in untreated down syndrome ( ds ) and untreated non - down syndrome children age 814 years old using the par and icon indices . materials and methods . this retrospective study evaluated pretreatment study models , intraoral photograp...
diabetes is the most common disease caused by metabolic disorders , which is accompanied by an increase in blood sugar . the treatment costs and also the rate of disability are high in diabetes , making it one of the main health care issues of patients . the metabolic disorders caused by diabetes mellitus result in...
background : diabetes mellitus is considered as the most common metabolic disorder . the patients with diabetes are likely to be affected by mental distress , especially depression . nurses should pay attention to the psychological needs of depressive patients by participating in an application of non - pharmacolog...
the heart is a complex , three - dimensional structure performing continuous , cyclic mechanical work to maintain blood circulation in the cardiovascular system . the performance of the cardiac pump primarily depends on myocyte efficiency , however , ventricular geometry , heart valve and vascular efficiency , loadin...
in this paper , the authors attempt to concisely present the anatomical and pathophysiological bases as well as the principles for echocardiographic evaluation of mechanical aspects of cardiac function based on speckle tracking method . this technique uses a phenomenon involving the formation of characteristic image ...
the genus streptococcus comprises 116 officially recognized species ( http://www.bacterio.net/ ) partially clustered into six species group ( pyogenic , anginosus , mitis , salivarius , bovis and mutans ) on the basis of systematic 16s rrna sequence study . the exact taxonomic classification of each species within th...
strain marseille - p2915 t , a gram - positive , facultative anaerobic and nonmotile coccus , was isolated from the gastric lavage of a patient with severe anaemia . the 16s rrna and rpob gene comparison exhibited a sequence identity of 98.7 and 92.6% with streptococcus infantis strain jcm 10157 t , respectively , co...
mesenchymal stem cells ( mscs ) are derived from the mesodermal germ layer and can be easily isolated and cultured from many tissues , such as bone marrow , adipose tissue , and amniotic fluid [ 13 ] . because mscs exhibit low expression of mhc i and do not express mhc ii molecules , these cells do not cause immunologi...
mesenchymal stem cells ( mscs ) can exhibit either prooncogenic or antitumor properties depending on the context . based on our previous study , we hypothesized that mscs engineered to deliver ifn- would kill cancer cells through persistent activation of the trail pathway . human bone - marrow ( bm- ) derived mscs we...
mandibular ameloblastoma is a rare , benign neoplasm of odontogenic epithelium described for the first time by broca ( 1868 ) as adamantinoma , and then re - coined by churchill ( 1934 ) . ameloblastoma accounts for about 1% of all tumors of the jaw , and it is mainly encountered during three to five decades of life ...
this case report presents a combination of surgical and prosthetic solutions applied to a case of oral implant rehabilitation in post - oncologic reconstructed mandible . bone resection due to surgical treatment of large mandibular neoplasm can cause long - span defects . currently , mandibular fibula free flap gra...