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this research is a case study on the medical mycology and parasitology course at the school of medicine of shiraz university of medical sciences ( sums ) .
the medical mycology and parasitology course is a sophomore - level course on the pathogenesis and treatment of mycotic and parasitic infections for medical stude... | backgroundthe seat selection and classroom dynamics may have mutual influence on the student performance and participation in both assigned and random seating arrangement.purposethe aim of the study was to understand the influence of seat selection on educational achievement.methodsthe seating positions of the medical ... |
constructs were cloned from full length mouse jmy4 , fly spire2 , and rat n - wasp using standard techniques .
jmy fragments were expressed as gst - fusions in e. coli and purified using a combination of glutathione and cation chromatography . except for individual wh2 domains ( supplementary fig .
s2 ) , the gst w... | many cellular structures are assembled from networks of actin filaments and the architecture of these networks depends on the mechanism by which the filaments are formed .
several classes of proteins are known to assemble new filaments , including the arp2/3 complex , which creates branched filament networks , and sp... |
diabetes mellitus has become a public health problem for the past couple of decades , and the exploration for therapies to combat this continues unabated .
bariatric surgery is already recognized as an effective therapeutic option for producing weight loss in morbidly obese patients , and it not only leads to subsequ... | aims .
although altered endocrine changes following bariatric surgery in morbidly obese patients with diabetes have been demonstrated by previous studies , little is known about their effects on low bmi patients of t2 dm .
we investigated the changes in adipokines and sicam-1 in chinese subjects with low bmi and t2... |
clinical details of our study group have been reported previously but are reproduced in table 1 for ease of reference . among the hemodialysis patients , no changes were observed in weight , kt / v , energy , and protein and mineral intakes at the beginning and end of the study ( p>0.05 ) .
median ( range ) serum tot... | abnormalities of bone mineral metabolism and vascular calcification are prevalent in patients with kidney failure . clinical management is based on biochemical targets , in particular parathyroid hormone ( pth ) concentrations , but this has many limitations including high biological variation .
a possible alternativ... |
the decreases in the fertile and pregnant populations and birth rate have accelerated the
aging of korean society , resulting in an increase in the elderly population . with the
increase in the elderly population , increased attention
should be given to the middle - aged
population , which includes people in th... | [ purpose ] this study was conducted to identify the effects of walking on the body
composition , health - related physical fitness , and serum lipids as part of efforts to
encourage middle - aged people to participate in walking as a regular and sustainable
exercise . [ methods ]
this study was conducted as a ... |
red cell transfusion ( rbc ) has been shown to be associated with increased patient morbidity and mortality .
rbc transfusion has been linked with increased duration of hospital stay , length of stay in the intensive care unit , duration on mechanical ventilation , risk of bacterial postoperative infection , and risk... | to reduce the rate of inappropriate red blood cell transfusion , a provider education program , followed by alerts in the computerized provider order entry system ( cpoe ) , was established to encourage aabb transfusion guidelines .
metrics were established for nonemergent inpatient transfusions .
service lines wit... |
vanadium is actually known as a trace element , essential for higher organisms although deficiency symptoms in humans have not yet been clearly identified ( guevara 1996 ) . trapping free oxygen radicals that might cause cardiac problems , it acts as a biological antioxidant and shows antitumoral activity ( scior et al... | the postulated transition of bis - maltolato - oxovanadium(iv ) ( bmov ) from its inactive trans- into its cis - aquo - bmov isomeric form in solution was simulated by means of computational molecular modeling .
the rotational barrier was calculated with dft
b3lyp under a stepwise optimization protocol with sto-3 g... |
ellis - van creveld syndrome ( evc , omim # 225500 ) , also known as chondroectodermal dysplasia , was first described by ellis and van creveld in 1940 .
the syndrome is caused by a mutation in the two genes evc1 and evc2 , mapping both on chromosome 4p16 , in a head to head configuration .
the disorder is commonly... | ellis - van creveld syndrome is a rare autosomal - recessive disorder characterized by short limbs , post - axial polydactyly , ectodermal dysplasia , edentulous mandibular incisor region , absence of mucobuccal fold , congenitally missing teeth , slight serrations of the alveolar ridge and multiple small alveolar notc... |
the common causes of gastric outlet obstruction include peptic ulcer disease , stomach cancer and gastrointestinal stromal tumor . impacted gallstone is a rare cause of intestinal obstruction and accounts for 1% to 3% of all intestinal obstructions.12 bouveret 's syndrome is a gastric outlet obstruction caused by an im... | bouveret 's syndrome is a gastric outlet obstruction caused by an impacted gallstone that passes through a cholecysto - gastric or cholecysto - duodenal fistula .
an elderly woman visited a local clinic with nausea and abdominal pain .
abdominal computed tomography revealed a stone that was impacted in the duodenal... |
multiple studies have shown that expression of tras by mtecs is critical for establishing self - tolerance to these antigens in the periphery ( 1 ) . in mice that express transgenes controlled by peripheral tissue - specific promoters , a scattered subset of mtecs express the transgenic antigen , and this expression is... | medullary thymic epithelial cells ( mtecs ) express a broad spectrum of tissue- restricted self - antigens ( tras ) , which are required for the development of central tolerance .
a new study suggests that tra expression is a specialized property of terminally differentiated mtecs .
however , as discussed here , an... |
tumour size is a commonly used predictor of survival in breast cancer and correlates strongly with lymph node involvement [ 15 ] .
tumour size is included in the american joint committee on cancer / union for international cancer control ( ajcc / uicc ) cancer staging manual and is represented by the maximum linear... | tumour size , most commonly measured by maximum linear extent , remains a strong predictor of survival in breast cancer .
tumour volume , proportional to the number of tumour cells , may be a more accurate surrogate for size .
we describe a novel
3d pathology volumetric technique for lumpectomies and compare it ... |
chronic actinic dermatitis ( cad ) is a severe photosensitivity disease induced by uvb , uva and occasionally visible light .
clinical manifestations include eczematous lesions , infiltrated plaques and pruritic erythematous papules , which develop on light - exposed areas , particularly the face , neck and upper che... | chronic actinic dermatitis is a chronic photosensitivity disorder characterized by severe eczematous lesions on sun - exposed skin areas .
we report a case of chronic actinic dermatitis presenting with leonine facies and secondary adrenal insufficiency , which was successfully treated with topical tacrolimus .
the ... |
multiple myeloma ( mm ) mainly affects men , with those aged 65 years on the average affected . as for its systemic symptoms , anemia , hypercalcemia , renal failure ,
increased risk of infection , are the main clinical characteristics ; for clinical symptoms at the head and neck area , pain on the affected bones , p... | multiple myeloma ( mm ) is a disease reported to account for 1% of all cancers and 10% of hematological malignant diseases . unlike other malignant diseases that are transferred to the osseous tissues ,
mm does not show new bone formation , is associated with characteristic osteolytic lesions , and shows monoclonal p... |
both natural and synthetic estrogens are capable of inducing renal neoplasms in syrian hamsters with an incidence approaching 100% . neither the sequence of events nor the mechanisms involved in estrogen carcinogenesis in this model have been established .
results presented here indicate that estrogen induces renal t... | |
as craniopharyngioma is a congenital brain tumor and benign in nature , total surgical removal is the ideal treatment .
however , total removal is often difficult without deterioration of qol of the patients because the tumor originates in the hypothalamic - pituitary axis . as the second choice , the residual tumor ... | abstractevaluation of 30 cases of craniopharyngioma treated by gamma knife at nagoya radiosurgery center ( nrc ) , nagoya kyoritsu hospital since july , 2004 has been made .
the mean volume of the tumor was 2.64 ml , which was treated with the marginal dose of 11.7 gy .
mean follow - up period was 79.9 months .
t... |
a common way to treat arterial stenoses due to atherosclerosis is percutaneous transluminal angioplasty ( pta ) , intended to improve the hemodynamic conditions .
this therapeutic procedure itself involves an injury to the vessel wall and the repair of the injury starts immediately post - pta . sometimes the repair p... | rationale and objectives . testing a quantitative , noninvasive method to assess postangioplasty vessel wall changes in an animal model .
material and methods .
six new zealand white rabbits were subjected to atherosclerotic injury , including cholesterol - enriched diet , deendothelialization , and percutaneous tr... |
systemic sclerosis ( ssc ) is a connective tissue disorder characterized by internal organ involvement , dermal thickening and fibrosis .
ssc is categorized into two groups : limited cutaneous ( lcssc ) and diffuse cutaneous ( dcssc ) forms .
the former ( the crest syndrome ) is characterized by calcinosis , raynau... | we report a case of fluoroscopy - guided intraarticular steroid injection for sternoclavicular joint ( scj ) arthritis caused by limited cutaneous systemic sclerosis ( ssc ) . a 50-year - old woman diagnosed with limited cutaneous ssc presented with swelling and pain in the right scj .
mri revealed signs of inflammat... |
renal tubular acidosis ( rta ) is a disorder of renal acidification out of proportion to the reduction in glomerular filtration rate characterized by normal anion gap ( ag ) metabolic acidosis .
type 1 rta can cause hypokalemia ; however , initial presentation of type1 rta with hypokalemic quadriparesis with bulbar w... | we report a 58-year - old woman who presented with acute quadriparesis , bulbar weakness , atrial fibrillation , ventricular ectopics , and distal renal tubular acidosis with severe hypokalemia .
she recovered completely on potassium and alkali supplementation .
the patient also had hypergammaglobulinemia with prob... |
civilization progress is associated with unfavorable changes in the lifestyle of the majority of human population .
improper diet , rich in fat and carbohydrates , and simultaneous limitation of physical activity can lead to the development of a severe metabolic disorder , diabetes . according to who estimates the wo... | aim : the purpose of the study was to evaluate the comparison of manual refraction versus autorefraction in diabetic retinopathy patients.material and methods : the study was conducted at the besat army hospital from 2013 - 2015 . in the present study differences between two common refractometry methods ( manual refrac... |
about 40% of patients have extra - nodal involvement of the skin , orbit , central nervous system , visceral organs and respiratory system .
we report a challenging case of extranodal rosai dorfman disease in a five - year - old child , initially misdiagnosed as orbital inflammatory disease .
the child 's first orb... | rosai dorfman disease ( rdd ) is characterized by histiocytic proliferation and massive cervical lymphadenopathy , although some patients have extra - nodal involvement .
we report a case of extranodal rdd in a five - year - old child , initially misdiagnosed as orbital inflammatory disease and treated with oral ste... |
eckert & ziegler bebig , gmbh , germany , introduced a new afterloading brachytherapy machine ( multisource ) .
it has two options to use either co or ir source for high dose rate ( hdr ) brachytherapy .
the co source has an advantage due to its longer half lives ( 5.27 years ) .
miniaturized co source with suffi... | purposethe purpose of this study is to obtain the dosimetric parameters of the new bebig 60co brachytherapy source following by tg-43u1 recommendation with appropriate electron cutoff energy ( 0.521 mev).material and methodsthe new bebig 60co brachytherapy source is used to calculate the tg-43u1 parameters .
egsnrc -... |
the home - made balloon sheath mainly consisted of an introducer sheath and a supporting balloon ( figs .
it was divided into four parts : the distal angulated part , the balloon part , the straight part , and the proximal handling part ( fig .
the introducer sheath was made of a polytetrafluoroethylene ( ptfe ) tu... | objectivewe wanted to evaluate the feasibility and usefulness of a newly designed balloon sheath for gastrointestinal guidance and access by conducting a phantom study.materials and methodsthe newly designed balloon sheath consisted of an introducer sheath and a supporting balloon .
a coil catheter was advanced over ... |
kyrle disease ( kd ; or hyperkeratosis follicularis et parafollicularis in cutem penetrans ) is a perforating dermatosis , first described in 1916 . apart from kd , the perforating dermatoses include elastosis perforans serpiginosa ( eps ) , perforating folliculitis ( pf ) , and acquired perforating collagenosis ( apc ... | a 59-year - old man with chronic renal failure and diabetes mellitus presented with pruritic crusted lesions which histologically were perforating disorders , showing features of both kyrle disease and acquired perforating collagenosis .
the mechanisms of transepidermal elimination and the classification of perforati... |
bacterial spot of tomato and pepper plants has been observed in areas with high humidity and warm climate .
the disease causes significant losses , estimated of about 1020% per year and it is one of the economically most important diseases in all continents where capsicum annuum and solanum lycopersicum l. are cultiv... | during the last 20 years , the causative agents of bacterial spot of tomato and pepper have been subjected to many studies and reclassifications . according to the current data , the species are four ( x. euvesicatoria , x. vesicatoria , x. gardneri , and x. perforans ) and cause similar symptoms in plants but possess ... |
one - third of the adult americans are obese and 2/3 are overweight [ 1 , 2 ] .
obesity increases histrionically and is becoming pandemic worldwide in the past decades , predisposing these populations to great risk for gastric esophageal reflux disease ( gerd ) and subsequent aspiration pneumonia , asthma , obstructi... | obesity becomes pandemic , predisposing these individuals to great risk for lung injury . in this review , we focused on the anti - inflammatories and addressed the following aspects : adipocytokines and obesity , inflammation and other mechanisms , adipocytokines and lung injury in obesity bridged by inflammation , an... |
venous leg ulcers ( vlus ) pose a serious clinical dilemma and an economic burden on health services .
they are frequently associated with morbidity , pain , and decreased quality of life in affected patients .
about 60% of patients with vlus will experience pain related to their wounds ( hofman et al 1997 ) , whic... | amelogenins are extracellular matrix proteins that , under physiological conditions , self - assemble into globular aggregates up to micron - sizes
. studies with periodontal fibroblasts indicate that attachment to these structures increases the endogenous secretion of multiple growth factors and cell proliferation .... |
adiponectin is a 30-kda ( acrp30 ) protein predominantly produced in the adipose tissue and circulates in the plasma as a trimer ( low molecular weight ) , a hexamer generated from two trimers , or as multimers consisting of 1218 hexamers ( high molecular weight ; hmw ) .
levels of adiponectin are decreased in obesit... | obesity in combination with diabetes and hypertension likely is contributing to the increasing incidence of chronic kidney disease ( ckd ) in the 21st century worldwide and requires novel insights and strategies for treatment .
there is an increasing recognition that the kidney has an important role in the complex in... |
afflictions of shoulder by tuberculosis is rare and when it occurs its more commonly a dry lesion ( caries sicca ) .
wet lesions in shoulder are rare and we report this case for the rarity of its occurrence .
a 55yrs old female patient presented with a painful swelling with restriction of movements of the right sho... | introduction : afflictions of shoulder by tuberculosis is rare and when it occurs its more commonly a dry lesion ( caries sicca ) .
wet lesions in shoulder are rare and we report this case for the rarity of its occurrence.case report : a 55yrs old female patient presented with a painful swelling with restriction of m... |
possible interactions between selenium and iodine metabolism were investigated in 7- to 16-year - old children with goiter ( n = 136 ) living in southeastern poland in iodine - deficient areas influenced by a sulfur industry .
the se - iodine interactions in these children were compared to the interactions in childre... | |
congenital epulis ( also known as congenital gingival granular cell tumour ) is a rare benign congenital growth of the newborn .
it was first described in 1871 by neumann , hence the alternative name is newmanns ' tumour .
it usually presents at birth with an obvious mass arising from the gingival mucosa of the max... | congenital epulis , also known as neumann 's tumour , is a rare congenital growth affecting the gingival mucosa of neonates .
it is benign condition , seen more frequently in females , with multiple epuli occurring in only 10% of cases .
the cause and origin of congenital epulis remains unclear . in this articl... |
ten to twenty percent of pancreatic cysts are neoplastic , while only 1% of pancreatic cysts are malignant .
serous and mucinous cystic neoplasms are two types of tumors of the exocrine pancreas , and have different biological behaviors .
mucinous cystic tumors are typically slow - growing , but carry a significant... | serous cystic neoplasms of the pancreas are almost always benign lesions . however , there are some case reports of malignant serous neoplasms of the pancreas .
it is very difficult to distinguish malignant and benign tumors .
indeed , only clinicopathologic findings of locoregional invasion and metastasis represen... |
the bilayer bending modulus ( kc ) is
one of the most important physical constants characterizing lipid
membranes , but precisely measuring it is a challenge , both experimentally
and computationally .
experimental measurements on chemically identical
bilayers often differ depending upon the techniques employ... | |
the consideration of institution of end - of - life care is an emotionally charged issue for the patient , their families and caregivers .
decisions are influenced by the beliefs of the caregivers , patients and their families . given the heterogeneity of many societies including our own , it is worthwhile to examine... | for most clinicians and patients , the discussion of palliative care is a difficult topic .
it is complicated by both the clinician 's and patient 's belief systems , which are frequently heavily influenced by cultural and religious upbringing .
this article discusses the impact of some of those differences on atti... |
various studies conducted on different photo anthropometry , but each one included some deficiencies and during the years , which were resolved .
the anthropometry studies can be divided into three categories : ( 1 ) manual anthropometry , ( 2 ) two - dimensional ( 2d ) photography and ( 3 ) three - dimensional ( 3d ... | various studies carried out on different photo anthropometry , but each one had some deficiencies which during the years they have been resolved . the objective of this paper is to test the efficiency of two - dimensional image processing software in photo anthropometry of hand . in this applied research , 204 office w... |
fusarium head blight ( fhb ) is a recurrent disease of wheat , barley , and other small grains across the world , also including northern europe , mainly caused by the fungal plant pathogens fusarium graminearum and fusarium culmorum ( bottalico and perrone 2002 ) .
fhb results not only in the premature bleaching of ... | sampling of straw bales from wheat , barley , and oats was carried out after harvest showing large variations in deoxynivalenol ( don ) and zearalenone ( zen ) levels . in the wheat field , don was detected in all straw samples with an average don concentration of 976 g / kg and a median of 525 g / kg , while in four... |
it is widely accepted that reactivation of hepatitis b virus ( hbv ) may occur along with an acute hepatitis after chemotherapy or immunosuppressive therapy.1 - 3 current recommendation is to give antiviral agents before starting these therapies.4 - 7 however , most of the reactivation cases are associated with high do... | hepatitis b virus ( hbv ) may be reactivated after chemotherapy or immunosuppressive therapy , and therefore administration of antiviral agents before such treatment is recommended .
most reported cases of reactivation are associated with high doses of immunosuppressive agents or combination therapy .
we present a ... |
origin of t. cruzi isolates - the 77 t. cruzi isolates
used in this study were deposited and have been maintained cryopreserved at
trypanosoma from wild and domestic mammals and vectors .
more information concerning the landscape physiognomy of pda , ra and una may be found in
the studies by lisboa et al .
1:... | here , we present a review of the dataset resulting from the 11-years follow - up of
trypanosoma cruzi infection in free - ranging populations of
leontopithecus rosalia ( golden lion tamarin ) and
leontopithecus chrysomelas ( golden - headed lion tamarin ) from
distinct forest fragments in atlantic coastal rain... |
chronic hepatitis c is a chronic disease and whose global prevalence is estimated at 3% of the world s population ( 1 ) . according to the word health organization , the assumed prevalence of chronic hepatitis c in bosnia and herzegovina is around 1.5% .
the current standard treatment of chronic hepatitis c in bosnia... | background : the current standard treatment of chronic hepatitis c in bosnia and herzegovina consists of pegylated interferon alpha in combination with ribavirin . interferon therapy has many psychiatric side effects , with depressive symptomatology being most prominent . the aim of the study was to establish the frequ... |
neck pain may originate from muscle , ligament , bursa , disc , neuromuscular junction , or from
other problems that result in pain .
neck pain can develop in any individual , generally first
presenting as a headache , but also sometimes as shoulder pain .
it is a cumulative condition
occurring because of mus... | [ purpose ] the objective of this study was to investigate the effects of shoulder
stability exercise on pain and function in neck pain patients . [ subjects ] the study design
consisted of a shoulder stability exercise group and a control group . [ methods ] the
effects of the therapies were evaluated using a vi... |
95% of tuberculosis ( tb ) of the female genital tract ( fgt ) is located in tissues other than the cervix .
a rare case of primary tb of the cervix which was diagnosed coincidently in a patient of endometrioma was reported in this study .
a 34 year old nullipara , a diagnosed case of endometrioma had a small cervi... | background:95% of tuberculosis ( tb ) of the female genital tract ( fgt ) is located in tissues other than the cervix .
a rare case of primary tb of the cervix which was diagnosed coincidently in a patient of endometrioma was reported in this study.case presentation : a 34 year old nullipara , a diagnosed case of end... |
we investigate the growth of graphene on polycrystalline
pt foils ( 25 m , 99.99% , alfa aesar ) by cvd using in situ sem
( see the methods section ) .
the samples are
first annealed in h2 ( 10 mbar ) at 9001000
c for 15 min to promote pt grain growth and remove adventitious
carbon from the surface of the f... | the
dynamics of graphene growth on polycrystalline pt foils during chemical
vapor deposition ( cvd ) are investigated using in situ scanning electron
microscopy and complementary structural characterization of the catalyst
with electron backscatter diffraction .
a general growth model is outlined
that consi... |
down syndrome ( ds ) , trisomy 21 , is the most common chromosomal abnormality in childhood and occurs in 1 in 1,000 births . among several physical and cognitive abnormalities ,
children with ds also have a 10- to 20-fold increased risk of leukemia relative to other children .
additionally , children with ds who a... | using a crispr / cas9 system , we have reengineered a translational start site in the gata1 gene in k562 cells .
this mutation accounts largely for the onset of myeloid leukemia in down syndrome ( ml - ds ) . for this reengineering , we utilized crispr / cas9 to generate mammalian cell lines that express truncated ve... |
wnt7a signals through its receptor fzd7 to activate the planar - cell - polarity pathway and drive the symmetric expansion of satellite stem cells resulting in enhanced repair of skeletal muscle . in differentiated myofibres
, we observed that wnt7a binding to fzd7 directly activates the akt / mtor growth pathway the... | |
glaucoma is treated initially with medical therapy or laser procedures . for patients who are unresponsive
, surgical treatments may be necessary , and traditionally these include trabeculectomy and tube shunts . if these procedures fail , options to decrease intraocular pressure ( iop ) are limited , and either repe... | the aim of this study is to report a case of gold shunt surgery for uncontrolled , low - tension glaucoma with good central vision , after having a previously failed trabeculectomy and tube shunt surgeries .
the patient was receiving maximum medical glaucoma therapy of four different types with intraocular pressure o... |
public reporting of hospital readmissions for heart failure ( hf ) underscores its importance as a measure of quality of care and as a metric for medicare reimbursements . among different racial / ethnic groups , older black and hispanic patients
have been reported to have higher 30day readmission rates compared with... | backgroundthe degree to which outcomes following hospitalization for acute heart failure ( hf ) vary by racial and ethnic groups is poorly characterized .
we sought to compare 30day and 1year rehospitalization and mortality rates for hf among 4 race / ethnic groups.methods and resultsusing the get with the guidelines... |
mediastinal abscesses ( mas ) in the pediatric population are relatively rare and usually occur as a complication of esophageal perforation , thoracic trauma , or thoracic surgery .
ma due to a non - traumatic etiology is extremely rare in childhood and usually results either from direct extension along contiguous an... | anterior mediastinal abscesses ( mas ) due to a non - traumatic etiology are extremely rare in childhood and only 13 such cases have been reported in the literature .
we report a 5-year - old male child with disseminated staphylococcal infection and a large non - traumatic anterior ma , who had a successful recovery ... |
in dupuytren s disease , the metacarpophalangeal ( mp ) , proximal interphalangeal ( pip ) , and distal interphalangeal ( dip ) joints can develop fixed - flexion deformities due to the development and subsequent contraction of diseased cords in the affected tissue .
although pip joints are not affected as often as a... | background and objectivedupuytren s contractures affecting proximal interphalangeal ( pip ) joints are challenging to treat .
we explored the effects of collagenase clostridium histolyticum ( cch ) on pip joint contractures after injection of an affected metacarpophalangeal ( mp ) joint in the same finger and after i... |
chagas ' disease is a zoonosis caused by the protozoan parasite trypanosoma cruzi , and it is a major public health problem in most of latin america and in particular in mexico .
t. cruzi infects many cell types , including myocytes , fibroblast , vascular endothelial , and smooth muscle cells among other cells .
s... | the acute phase of chagas ' disease in mice and human is marked by states of immunosuppression , in which trypanosoma cruzi replicates extensively and releases immunomodulatory molecules that delay parasite - specific responses mediated by effector t cells .
this mechanism of evasion allows the parasite to spread in ... |
chronic obstructive pulmonary disease ( copd ) is a rising epidemic which is responsible for one in six deaths currently and is predicted to rise to one in three deaths by 2020.1 the disease is high cost , with advanced copd patients having repeat admissions with average stays of 811 days.2 these admissions are due to ... | hypercapnic respiratory failure is common in advanced chronic obstructive pulmonary disease and is usually treated by nasal ventilation .
not all patients requiring such ventilation can tolerate it , with anxiety and phobia influencing their reaction , along with treatment failure .
we report the case histories of ... |
proteins fold because water is a marginal
solvent for peptide polymer
chains . changing the quality of the solvent
affects
solution stability or aggregation and is usually accompanied by changes
in protein stability .
timasheff and co - workers have analyzed changes in
protein stability and solubility in ... | experimentally , the solubility of
oligoglycines in water decreases
as its length increases .
computationally , the free energy of solvation
becomes more favorable with chain length for short ( n = 15 ) oligoglycines .
we present results of large scale simulations
with over 600 pentaglycines at varying conc... |
experiments were performed in accordance with the national institutes of health guide for the care and use of laboratory animals .
all protocols were approved by the institutional animal care and use committee of the mayo clinic .
mice heterozygous for a loss of function mutation in the csf1 gene were obtained from... | background & aimsdiabetic gastroparesis is associated with changes in interstitial cells of cajal ( icc ) , neurons , and smooth muscle cells in both animal models and humans .
macrophages appear to be critical to the development of cellular damage that leads to delayed gastric emptying ( ge ) , but the mechanisms in... |
we use urethane ( 1.5 g / kg , sigma - aldrich co. , st .
luis , mo ) - prepared as 20% solution by diluting 20 g of urethane in 100 ml of phosphate buffered saline ( pbs ) i.e. the animal will receive 7.5 ml / kg of urethane solution intraperitonealy ( ip ) .
because of its dose - response curve , the total dose o... | large scale electrophysiological recordings from neuronal ensembles offer the opportunity to investigate how the brain orchestrates the wide variety of behaviors from the spiking activity of its neurons .
one of the most effective methods to monitor spiking activity from a large number of neurons in multiple local ne... |
it is estimated that 366 million people worldwide in the age of 2079 years were affected by diabetes in 2010 and the prevalence is expected to increase to 552 million people in 2030 .
cardiovascular disease is the main cause of death among people with diabetes , accounting for 50% of all diabetic deaths .
diabetes ... | the aim of the present study was to examine the calcium activity of c8-t5 dorsal root ganglion ( drg ) neurons from zucker diabetic fatty rats .
in total , 8 diabetic zdf fatty animals and 8 age - matched control zdf lean rats were employed in the study .
c8-t5 dorsal root ganglia were isolated bilaterally from 14 ... |
sirenomelia is a rare and fatal congenital defect characterized by varying degrees of lower limb fusion , thoracolumbar spinal anomalies , sacrococcygeal agenesis , genitourinary , and anorectal atresia .
the incidence of sirenomelia is 0.8 - 1 case/100,000 births with male to female ratio being 3:1 .
the rarity of... | sirenomelia ( mermaid syndrome ) is a rare congenital fetal anomaly with characteristic feature of complete or partial fusion of lower limbs . although , this syndrome is incompatible with life due to the association of several congenital visceral abnormalities ; however , there are few reports of surviving infants .
... |
assembly of separate
phases within a single bulk grain is important
in the production of structural and functional materials : it can determine
the mechanical properties of steels and
optimize thermoelectric performance .
vertical
nanocomposites in heteroepitaxial thin films enable combination of the proper... | complex
transition - metal oxides are important functional materials
in areas such as energy and information storage .
the cubic abo3 perovskite is an archetypal example of this class , formed
by the occupation of small octahedral b - sites within an ao3 network defined by larger a cations .
we show that intr... |
retinoblastoma is a highly malignant tumor of the eye that grows relentlessly and almost always has a fatal outcome if untreated .
both sexes are affected equally , and the tumor has no predilection for the right or left eye .
it has an incidence varying from 1 in 3300 to 1 in 20,000 live births , and accounts for ... | retinoblastoma is a highly malignant neoplasm .
most of the cases are usually far advanced at the time of detection , requiring enucleation to salvage the child 's life
. however , the cosmetic rehabilitation of these patients should always be an integral part of their treatment , which helps in their re - integrat... |
skin aging is a complex process induced by constant exposure to ultraviolet ( uv ) irradiation .
uv generates reactive oxygen species leading to collagen deficiency and eventually skin wrinkling ( 1 , 2 ) . aging of the skin is characterized by irregular pigmentation , increased wrinkling , loss of elasticity , dryne... | background and the purpose of studyskin aging is a complex process induced by constant exposure to ultraviolet ( uv ) irradiation and damages human skin .
uv generates reactive oxygen species leading to collagen deficiency and eventually skin wrinkling .
basil contains a number of phenolics and favonoids which poss... |
direct oral anticoagulants ( doacs ) , targeting activated coagulation proteases , have been recently introduced in therapeutics for stroke prevention in patients with nonvalvular atrial fibrillation , and prevention and treatment of venous thromboembolism ; they are currently in development for various other indicatio... | idarucizumab is the first targeted antidote of dabigatran , a direct oral anticoagulant used for prevention and treatment of venous thromboembolism and prevention of stroke in atrial fibrillation .
idarucizumab is a humanized fragment of a monoclonal antibody , which binds dabigatran reversibly with high affinity and... |
this was a prospective , open - label , multicenter , observational , postmarket study evaluating vyc-17.5l for the treatment of moderate to severe nlfs .
assessments were conducted : ( 1 ) at baseline , ( 2 ) after initial treatment ( day 0 ) , ( 3 ) 2 weeks after initial treatment , ( 4 ) after top - up ( performed... | backgroundvyc-17.5l ( 17.5 mg / ml hyaluronic acid , 0.3% lidocaine ) is a dermal filler intended for deep dermis injection for the treatment of skin depressions.objectiveto evaluate 12-month effectiveness and safety of vyc-17.5l for the treatment of moderate / severe nasolabial folds ( nlfs).methodssubjects 18 years o... |
patients with hemiparesis due to stroke tend to use the non - affected side of the body
rather than the affected side1 .
therefore ,
muscle weakness in the upper and lower extremities of the affected side increases , and
asymmetric body alignment and weight shift can occur2 .
improvement of
independent walk... | [ purpose ] the purpose of this study was to determine the effect of ground
tilt on the lower extremity muscle activity of stroke patients performing squat exercises .
[ subjects ] fifteen hemiparetic patients volunteered to participate in this study .
[ methods ] the subjects performed squat exercises at three d... |
we retrospectively reviewed 245 patients ( 246 knees ) who underwent medial uka between may 2002 and may 2010 for degenerative arthritis developed in the medial compartment of the knee , and tracked the follow - up for more than 1 year .
there were 37 men and 208 women ; overall mean age was 64.3 years ( range , 50 t... | backgroundwe report intra- and postoperative complications of unicompartmental knee arthroplasty ( uka).methodsthis study was conducted on 246 cases of uka which were performed for degenerative osteoarthritis confined to the medial compartment , from may 2002 to may 2010 , for which follow - up periods longer than one ... |
the detection and characterization of shiga toxin producing escherichia coli ( stec ) , salmonella spp . , and yersinia enterocolitica strains in human patients , animal reservoirs , and foods of animal origin intended for human consumption are relevant to public health .
these organisms are transmitted through conta... | shiga toxin producing escherichia coli ( stec ) , salmonella spp . , and yersinia species was investigated in humans , animals , and foods in san luis , argentina .
a total of 453 samples were analyzed by culture and pcr .
the antimicrobial susceptibility of all the strains was studied , the genomic relationships a... |
patient satisfaction ( ps ) is the measure of quality in healthcare perceived by patients and roots in different complicated factors ( 1 ) .
several factors should be coordinated with each other to make an appropriate condition for developing and improvement of ps with observing patient 's rights in all aspects ( 2 )... | introduction : methodologically correct assessment of patient satisfaction ( ps ) plays a crucial role for quality - improvement purposes .
evaluation of iranian literature on emergency department s ps resulted in an emerging need for developing a new instrument with satisfactory psychometric properties .
the prese... |
vision serves as a vital function ensuring the feeling of control over the immediate surroundings and creating a sense of contact with the world .
therefore , the fact does not render it peculiar that cases connected with vision disturbances and eyesight loss entail heightened anxiety and the fear for autonomy limita... | purpose .
this study aims at evaluating coping style and quality of life in patients with glaucoma and cataract .
methods .
the participants were patients ( n = 237 , 130f ; mean age : m = 67,8 ; sd = 9,5 ) with low vision caused by cataract ( n = 188 ) and glaucoma ( n = 49 ) who answered the quality of life que... |
we report on the use of graphene
for room temperature on - chip detection and generation of pulsed terahertz
( thz ) frequency radiation , exploiting the fast carrier dynamics of
light - generated hot carriers , and compare our results with conventional
low - temperature - grown gallium arsenide ( lt - gaas ) p... | |
oral lichen planus ( olp ) is a t - cell - mediated chronic inflammatory oral mucosal disease of unknown etiology , but it is believed to result from an abnormal t - cell - mediated immune response in which basal epithelial cells are recognized as foreign body because of changes in the antigenicity of their cell surfac... | aim and objectives : to investigate the efficacy of 0.1% tacrolimus with colgate oraguard - b paste for the treatment of patients with oral lichen planus ( olp).materials and methods : one hundred and fifty patients with symptomatic olp participated in the study , who had clinically and histopathologically proven olp .... |
hyoscine - n - butyl bromide ( hbb ) is a widely used antispasmodic and anticholinergic drug belonging to the belladonna alkaloid class of semisynthetic quaternary ammonium compounds .
these compounds exert a spasmolytic action on the smooth muscles of the bile - gastrointestinal tract,1 the genitourinary tract , the... | hyoscine - n - butyl bromide is a widely used antispasmodic belonging to the belladonna alkaloid class of semisynthetic quaternary ammonium compounds .
these compounds exert a spasmolytic action on the smooth muscles of the bile - gastrointestinal tract , genitourinary tract , salivary glands ( xerostomia ) , and als... |
two major vascular pathologies underlie brain damage in patients who have important abnormalities involving small size penetrating brain arteries and arterioles ; 1 ) thickening of the arterial media with encroachment on the arterial lumens and 2 ) obstruction of the origins of penetrating arteries by parent large intr... | two major vascular pathologies underlie brain damage in patients with disease of small size penetrating brain arteries and arterioles ; 1 ) thickening of the arterial media and 2 ) obstruction of the origins of penetrating arteries by parent artery intimal plaques .
the media of these small vessels may be thickened b... |
occipital neuralgia ( on ) refers to a paroxysmal stabbing pain , with or without persistent aching between paroxysms , in the distributions of the greater or lesser occipital nerves .
nervus intermedius neuralgia ( nin ) usually provokes a very intense and stabbing pain localized in the depth of the ear canal , whic... | cranial nerve neuralgia usually occurs sporadically .
nonetheless , familial cases of trigeminal neuralgia are not uncommon with a reported incidence of 12% , suggestive of an autosomal dominant inheritance .
in contrast , familial occipital neuralgia is rarely reported with only one report in the literature .
we... |
over twenty unstable and expanded microsatellite repeats have been identified as the cause of human neurological disorders .
these repeats , mostly consisting of trinucleotides or tetranucleotides , are considered dynamic mutations ; they possess the unusual characteristic that repeat tract length is variable .
mos... | an expanded ctg - repeat in the 3 utr of the dmpk gene is responsible for myotonic dystrophy type i ( dm1 ) .
somatic and intergenerational instability cause the disease to become more severe during life and in subsequent generations .
evidence is accumulating that trinucleotide repeat instability and disease progr... |
odontogenic infections are one of the most prevalent diseases worldwide and the principal reason for seeking dental care . dental prescriptions account for nearly 7% to 11% of all common antibiotic prescriptions .
the commonest emergency odontogenic infections are periapical abscess ( 25% ) , pericoronitis ( 11% ) , ... | background . treatment of odontogenic infections includes surgical drainage and adjunctive antibiotics .
this study was designed to generate efficacy and safety data to support twice daily dosing of amoxicillin / clavulanic acid compared to clindamycin in odontogenic infections .
methods .
this was a phase iv , r... |
diabetic retinopathy ( dr ) is a leading cause of visual disability and blindness worldwide . according to the world health organization ( who )
, the prevalence of diabetes in the eastern mediterranean region is estimated to be between 5% to 15%.1 in bahrain , the number of diabetics is 150,0002 and the prevalence i... | purpose : to develop an integrated diabetic retinopathy screening program that uses telemedicine.materials and methods : in this evaluation of diagnostic technology , six telemedical screening units were established to cover all regions of bahrain . the units were equipped with a digital fundus camera at the primary he... |
hemolytic uremic syndrome ( hus ) , a common cause of acute renal failure in children , is one of a group of disorders referred to as thrombotic microangiopathies . hus - related symptoms include fever , microangiopathic hemolytic anemia , thrombocytopenia and renal failure .
prior association of hus resulting from... | thrombotic microangiopathies are disorders resulting from platelet thromboses forming in the microvasculature with resultant schistocyte forms .
hemolytic uremic syndrome ( hus ) is a microangiopathic hemolytic anemia often complicated by acute renal failure in children .
hus is typically caused by bacterial infect... |
transcatheter aortic valve implantation ( tavi ) to treat severe , calcific aortic stenosis ( as ) has been shown to be both feasible and beneficial in those at prohibitive or high risk for surgical aortic valve replacement ( savr ) risk.1
2 previous surgical series have frequently identified mitral regurgitation ( m... | objectiveto identify the effects of preprocedural significant mitral regurgitation ( mr ) and change in mr severity upon mortality after transcatheter aortic valve implantation ( tavi ) using the edwards sapien system.methodsa retrospective analysis of 316 consecutive patients undergoing tavi for aortic stenosis at a s... |
potential is essential for survival following partial hepatic resection ( e.g. , for tumor removal or live - donor liver transplantation ) and from acute and chronic liver injury secondary to toxins , infections , immune dysfunction , metabolic diseases , or other causes [ 13 ] .
nevertheless , liver diseases remain ... | the regenerative capacity of the liver is well known , and the mechanisms that regulate this process have been extensively studied using experimental model systems including surgical resection and hepatotoxin exposure .
the response to primary mitogens has also been used to investigate the regulation of hepatocellula... |
depression is one of the most common mental health problems and is a significant cause of morbidity .
depression interferes with daily functioning and quality of life and places significant burden on the health care system.1 depression is also an important risk factor for suicide.2 many factors contribute to the etio... | backgroundthe aim of this study was to investigate the associations between ambient air pollution and emergency department ( ed ) visits for depression.methodshealth data were retrieved from the national ambulatory care reporting system .
ed visits for depression were retrieved from the national ambulatory care repor... |
wound healing is a dynamic process involving many factors and cell types including soluble mediators , blood cells , fibroblasts , endothelial cells , and extracellular matrix .
normal wound healing is divided into several sequential phases that overlap in space and time : homeostasis , inflammation , granulation tis... | by 2025 , more than 500 m people worldwide will suffer from diabetes ; 125 m will develop foot ulcer(s ) and 20 m will undergo an amputation , creating a major health problem . understanding how these wounds become chronic will provide insights to reverse chronicity .
we hypothesized that oxidative stress ( os ) i... |
in the midnight of august 6 , 2010 , leh in ladakh region of north india received a heavy downpour .
the cloud burst occurred all of a sudden that caught everyone unawares . within a short span of about 2 h , it recorded a rainfall of 14 inches .
there were flash floods , and the indus river and its tributaries and... | background : on august 6 , 2010 , in the dark of the midnight , there were flash floods due to cloud burst in leh in ladakh region of north india .
it rained 14 inches in 2 hours , causing loss of human life and destruction .
the civil hospital of leh was badly damaged and rendered dysfunctional .
search and resc... |
first , the widespread adoption of commercial ehr systems presents a barrier to researchers and investigators seeking to deploy or integrate new tools and interventions into clinical practice .
second , despite their challenges , ehrs will remain the primary method of collecting / generating clinical data yet there ... | the widespread adoption of commercial electronic health records ( ehrs ) presents a significant challenge to the field of informatics . in their current form ,
ehrs function as a walled garden and prevent the integration of outside tools and services .
this impedes the widespread adoption and diffusion of research ... |
binding selectivity is one of the most
important requirements for
the development of a safe therapeutic ; in fact , large differences
in binding affinity between the intended target and similar proteins
are often sought in order to avoid unwanted and often unknown side
effects .
conversely , in some cases a... | binding
selectivity is a requirement for the development of a safe
drug , and it is a critical property for chemical probes used in preclinical
target validation .
engineering selectivity adds considerable complexity
to the rational design of new drugs , as it involves the optimization
of multiple binding a... |
traditionally , students learned in the classroom through interaction with the teachers , which required his physical presence and confidence in asking questions to clear his doubts
. many students may not take part in the discussion openly due to peer pressure and fear of asking a question that may appear silly and ... | background : although lecture handouts are commonly given to students during theory lectures , students perception , as well as their performance , can vary depending on the type of handouts they receive for information processing.methodology:this is a quasi - experimental study involving 6th semester medical students ... |
a 16-year - old female patient was referred to our pain clinic from the orthopedic department with persistent pain and swelling of the right forearm .
the patient 's history revealed her being admitted to a local hospital with urinary tract infection and receiving an infusion of 5% dextrose with 0.9% saline through a... | due to its complex pathophysiology and wide spectrum of clinical manifestations , the diagnosis of crps is often missed in the early stage by primary care physicians . after being treated by a primary care physician for 5 months for chronic cellulitis
, a 16-year - old girl was referred to our hospital with features ... |
true aneurysms , or diverticulae , of the mitral valve are a rare cause of mitral regurgitation .
it occurs most commonly in association with aortic valve infective endocarditis,1 - 5 ) but they may also present with mitral valve infective endocarditis,5 - 7 ) chronic mitral regurgitation8 ) or as a complication of m... | aneurysm of the mitral valve , although uncommon , occurs most commonly in association with infective endocarditis of the aortic valve and true mitral valve aneurysm is a rare cause of mitral regurgitation .
we report a case with perforated mitral valve aneurysm in the posterior leaflet without concurrent infective e... |
the fermentation of fatty low - value renewable carbon sources aiming at the production of various added - value metabolites such as organic acids , single - cell oil , and lipases presents a noticeable interest in the sector of industrial microbiology and biotechnology [ 13 ] .
the yeast yarrowia lipolytica degr... | the nonconventional yeast yarrowia lipolytica degrades very efficiently hydrophobic substrates to produce organic acids , single - cell oil , lipases , and so forth .
the aim of this study was to investigate the biochemical behavior and simultaneous production of valuable metabolites such as lipase , citric acid ( ca... |
papillary cystadenoma of the salivary glands is an uncommon benign neoplasm , which usually occurs in the minor salivary glands , and very rarely in the major salivary glands .
extensive oncocytic change may be seen , and these lesions are classified as oncocytic variants .
we report three cases of oncocytic papill... | oncocytic papillary cystadenoma ( opc ) in the major salivary glands is extremely rare .
we report three cases of these cystadenomas arising in major salivary glands , with varied cytologic features .
case 1 : a 38-year - old man presented with a right parotid gland mass that showed papillary clusters of oncocytic ... |
supplementary material is available in the online version of this article at ( doi : 10.1007/s11671 - 007 - 9043 - 2 ) and is accessible for authorized users . | simple nanoporous alumina matrix modification procedure , in which the electrically highly insulating alumina barrier layer at the bottom of the pores is replaced with the conductive layer of the gold beds , was described .
this modification makes possible the direct electron exchange between the underlying aluminum ... |
despite its terrifying impact on health , tobacco use is widespread throughout the world .
if no effective interventions are introduced and implemented against it , up to one
billion people will die from tobacco use in the 21st century .
youth smoking is a concern for industrial , low - income , and middle - inco... | objective : smoking is a serious problem that has a devastating impact on health . the
objective of this study was to describe the prevalence of and factors influencing
smoking among medical and non - medical students in tbilisi , georgia , as well as to
determine whether medical education has an impact on smokin... |
one of the most widely consumed beverages throughout the world is tea produced from the tea plant ( camellia sinensis ) .
geographical consumption patterns of the different teas vary greatly with green tea consumed mainly in asia and the middle east and black tea consumed mostly in western countries .
this together... | tea ( camellia sinensis ) is a widely consumed beverage and recognised for its potential enhancing effect on human health due to its rich polyphenol content .
while a number of studies have investigated the quantity and type of polyphenols present in different tea samples , no study has reported the potential effect ... |
diagnosis and treatment of congenital heart disease have changed dramatically over the last few decades .
the relative importance of preoperative morbidity and mortality has been increasing as a result of the great improvements in perioperative and long - term survival .
this is especially true for critical congeni... | pulse oximetry screening ( pos ) has been proposed as an effective , noninvasive , inexpensive tool allowing earlier diagnosis of critical congenital heart disease ( cchd ) .
our aim was to test the hypothesis that pos can reduce the diagnostic gap in cchd in daily clinical routine in the setting of tertiary , second... |
fetal blood can enter the maternal circulation and a diagnosis of clinical fetomaternal hemorrhage ( fmh ) is made when fetal blood loss reaches a significant level leading to clinical symptoms due to fetal anemia , such as an abnormal fetal heart rate ( fhr ) patterns , decreased fetal movement , and/or fetal hydrops ... | key clinical messageit is not clear that how long the affected fetuses can tolerate fetomaternal hemorrhage ( fmh ) .
incidental serial measurements of the fetal peak systolic velocity of the middle cerebral artery and the retrospective analysis of stocked blood available incidentally indicated that our patient had s... |
minor salivary gland tumors include a heterogeneous group of neoplasms with varied histology accounting for 10 - 15% of all salivary gland neoplasms , most of which are located in the palate .
it was first described by sheldon et al . in 1943 and was considered a variant of pleomorphic adenoma . in 1991 , the world h... | myoepitheliomas account for less than 1% of all salivary gland tumors and mostly occur in the parotid gland and palate .
a 58-year old male patient reported to the outpatient department of pms college of dental science and research ( kerala , india ) with a slow growing painless swelling on the palate for 4 years .
... |
a 26-year - old male presented to us following a seizure with left sided weakness ( 4-/5 , medical research council ( mrc ) grade ) .
the past medical history was significant for a traumatic brain injury seven years prior that involved a depressed skull fracture after being hit with a baseball bat .
a brain compute... | a 26-year - old male presented with delayed intracerebral hemorrhage from a ruptured distal middle cerebral artery pseudoaneurysm that followed a compound depressed skull fracture from years ago .
the brain protrusion through the skull defect likely resulted in stretching and subsequent tearing of the arterial wall r... |
wolff - parkinson - white ( wpw ) syndrome is characterized by ventricular pre - excitation that ventricles are electrically and mechanically pre - excited through an accessory pathway , which connects atria and ventricles .
a rare cause of morbidity in infants and children with wpw syndrome is left ventricular ( lv ... | left ventricular ( lv ) dysfunction and dilated cardiomyopathy ( dcm ) are rarely attributable to sustained or incessant tachyarrhythmias in infants and children with wolff - parkinson - white ( wpw ) syndrome .
however , several recent reports suggested that significant lv dysfunction may develop in wpw syndrome in ... |
insertion of the double j catheter into the ureter , which facilitates drainage of the upper urinary tract , is one of the most common urological procedures this medical procedure is generally thought of as quite easy and safe to perform , with a very low rate of severe complications .
nevertheless , as any other me... | introductionthe aim of the trial was to estimate the relationship between colonization of the double j catheter , and the microorganisms cultured from urine.material and methods60 patients , who had double
j catheters inserted , participated in the study .
all the subjects had their midstream urine samples taken p... |
on rare occasions , pheochromocytoma and ganglioneuroma develop together within a single adrenal medullary tumor1 - 3 ) .
it is apparent that composite tumors of that type may display symptoms referable to hormonal hypersecretion by either portion of the tumor1 ) .
yet , pheochromocytomas commonly act in the typica... | composite adrenal medullary tumors , composed of both pheochromocytoma and ganglioneuroma , are extremely rare , as are pheochromocytomas masquerading as acute relapsing pancreatitis .
we recently experienced a case of a 48-year - old male with both these phenomena .
the patient complained of an acute onset of inte... |
matrix - assisted laser desorption ionization ( maldi ) is a method of wide analytical interest , representing an effective approach to obtain information on the molecular weight of macromolecules . due to the privileged formation of singly charged molecular species ( [ m + h ] , [ m h ] , alkali cationized molecule... | a mechanism is proposed for the first step of ionization occurring in matrix - assisted laser desorption ionization , leading to protonated and deprotonated matrix ( ma ) molecules ( [ ma + h]+ and [ ma h] ions ) .
it is based on observation that in solid state , for carboxyl - containing maldi matrices , the molecu... |
in the diabetes care in general practice study ( 10 ) , 474 general practitioners agreed to include all subjects on their practice list who fulfilled the following criteria : newly diagnosed diabetes based on hyperglycemia symptoms and/or raised blood glucose values , diagnosed between 1 march 1989 and 28 february 1992... | objectivewe recently showed that rna oxidation , estimated by urinary excretion of 8-oxo-7,8-dihydroguanosine ( 8-oxoguo ) , independently predicted mortality in a cohort of 1,381 treatment - naive patients with newly diagnosed type 2 diabetes . in the present investigation , we analyzed urine collected 6 years after t... |
coronary heart disease ( chd ) is one of the most common and dangerous human diseases .
it is a major cause of disability and the most common cause of death ; especially in industrialized societies .
atherosclerosis is a chronic inflammatory disease that many factors are involved in its pathogenesis ( 2 ) .
the c... | background : the aim of this study was to detect fungi in atherosclerotic plaques and investigate their possible role in atherosclerosis.methods:coronary atherosclerotic plaques specimen were obtained from patients with atherosclerosis . direct examination , culture ,
histopathology study , pcr and sequencing were pe... |
a mobile plaque ( mp ) in the carotid artery is an uncommon condition which can be detected with duplex ultrasound , and it is associated with a high risk of ischemic stroke .
carotid endarterectomy ( cea ) is an option for patients who are refractory to medical treatment ; however , the risks of intraoperative embol... | we report a case of progressive ischemic stroke due to a mobile plaque , in which carotid artery stenting successfully prevented further infarctions . a 78-year - old man developed acute multiple infarcts in the right hemisphere , and a duplex ultrasound showed a mobile plaque involving the bifurcation of the left comm... |
in korea , cancer has ranked highest among all causes of death . during 2009 ,
the cancer incidence rate for all sites combined showed an annual increase of 3.3% ( 1.6% in males , 5.3% in females ) from 1999 to 2009 . in an effort to reduce the burden of cancer ,
national cancer control programs were formulated by ... | purposethe korean national cancer screening survey ( kncss ) , a nationwide , annual cross - sectional survey , has been conducted since 2004 .
the current study was conducted in order to report on trends in cancer screening rates for five types of cancer ( stomach , liver , colorectal , breast , and cervix uteri).ma... |
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