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as a special group suffering from ovarian cyst , infants often present with distinctiveness in its occurrence , development , and prognosis . however , pedicle torsion of ovarian cyst or intracystic hemorrhage is often encountered among infants in clinic , which usually result in unfavorable consequence such as ovari...
background : to discuss the experience of diagnosis and treatment of ovarian cyst in infants.materials and methods : a retrospective review was conducted on 20 infants who suffered from ovarian cyst.results:there were no dysplasia ovarian was found in children which were preoperatively diagnosed simplex cyst . within t...
nitrous oxide ( n2o ) is the thirdmostimportant , longlived greenhouse gas , after carbon dioxide and methane [ myhre et al . , these topthree greenhouse gases have a mixture of natural and anthropogenic sources , and the challenge has always been to quantify the human perturbation to their budgets [ prather et al . ...
abstractthe lifetime of nitrous oxide , the thirdmostimportant humanemitted greenhouse gas , is based to date primarily on model studies or scaling to other gases . this work calculates a semiempirical lifetime based on microwave limb sounder satellite measurements of stratospheric profiles of nitrous oxide , ozone ,...
the word urticaria is derived from the latin word urtica which refers to the stinging nettle plant , now known to contain histamine . approximately 15 - 20% of the population will have urticaria at least once during their lifetime . this is referred to as chronic idiopathic urticaria or more recently , as chronic...
background : autologous serum skin test ( asst ) is a simple in - vivo clinical test for the detection of basophil histamine releasing activity and to diagnose chronic autoimmune urticaria ( cau ) among chronic spontaneous urticaria ( csu ) patients . diagnosing these patients is also important as they may need high do...
lung cancer is one of the leading cancers worldwide , with an estimated 1.8 million new cases recorded in 2012 . according to the world health organization ( who ) , lung cancer accounted for approximately 1.59 million cases of the 8.2 million cancer - related deaths reported in 2012 ; as such , lung cancer is one of...
objective : lung cancer is one of the leading cancers and major causes of cancer mortality worldwide . the economic burden associated with the high mortality of lung cancer is high , which accounts for nearly $ 180 billion on a global scale in 2008 . this paper aims to understand the economic burden of lung cancer in...
cation diffusion facilitator ca - sensitive cross - complementer 1 inositol 1 , 4 , 5-trisphosphate receptor vacuolar iron transporter vacuolar transporter chaperone acidocalcisomes were first identified in trypanosomes and later found from bacteria to human cells . although originally described in bacteria as metach...
trypanosoma brucei , the causative agent of african trypanosomiasis , is a unicellular parasite that possesses lysosome - related organelles known as acidocalcisomes . these organelles have been found from bacteria to human cells , and are characterized by their acidic nature and high calcium and polyphosphate ( po...
transpedicular screw fixation has been the treatment of choice for stabilizing segmental instability and in cases which wide decompression is required . however , the use of pedicle screw is not suitable for all cases of degenerative spine disease . there are some disadvantages such as postoperative back pain resulte...
objectivetranspedicular screw fixation has some disadvantages such as postoperative back pain through wide muscle dissection , long operative time , and cephalad adjacent segmental degeneration ( asd ) . the purposes of this study are investigation and comparison of radiological and clinical results between interspin...
triad studied a random sample of adults with diabetes enrolled in 10 health plans in eight states ( hawaii , california , texas , indiana , michigan , new york , new jersey , and pennsylvania ) that served 180,000 patients with diabetes . patients were eligible to participate if they were at least 18 years old , live...
objectiveto examine demographic , socioeconomic , and biological risk factors for all - cause , cardiovascular , and noncardiovascular mortality in patients with type 2 diabetes over 8 years and to construct mortality prediction equations.research design and methodsbeginning in 2000 , survey and medical record informat...
type 2 diabetes mellitus ( t2 dm ) is a chronic metabolic disease characterized by hyperglycemia and , resulting from insulin resistance and impaired insulin secretion . clinical management of t2 dm consists of nutrition therapy , pharmacological therapy , and exercise1 . the american college of sports medi...
[ purpose ] the primary objective of this study was to investigate the effect of low - intensity exercise training compare with high - intensity exercise training on endoplasmic reticulum stress and glucagon - like peptide-1 in adolescents with type 2 diabetes mellitus . [ subjects and methods ] the low - intensi...
the most frequent metastasis sites of synovial sarcoma are the lungs , lymph nodes , and bone . pancreatic metastasis is quite rare ; only 3 cases have been reported worldwide to date . a 32-year - old man underwent extended excision of synovial sarcoma in the left pelvis and femur in 2009 . in 2013 , follow - up c...
abstractintroduction : synovial sarcoma is a malignant soft tissue sarcoma which arises near joints . the most frequent metastasis sites of synovial sarcoma are the lungs , lymph nodes , and bone . pancreatic metastasis is quite rare ; only 3 cases have been reported worldwide to date . we herein present the 4th ...
oral cancers became an important part of oro - maxilo - facial pathology because of its increased frequency , the low rate of survival , as well as the resulted functional or physiognomical defects . multiple mechanisms are acting at a molecular level and induce the neoplazic transformation of the squamous cells . at...
the study that was carried out was comprised of 117 cases of oral squamous carcinomas , selected in two years interval , between 2007 - 2008 . the tumors were diagnosed especially at patients between the ages of 50 and 79 years , 96,6% being over 40 years old . it came out a clear predominance of the male sex in ap...
the lh / hcg ( luteinizing hormone / human chorionic gonadotropin ) receptor ( lhr ) expressed in the gonads regulates the ovarian and testicular function123 . although gonadal tissues are the primary sites of its expression , it is now well - established that lhr is also expressed in many non - gonadal tissues4 . lh...
a specific luteinizing hormone receptor ( lhr ) mrna binding protein ( lrbp ) has been identified and purified . this lh receptor mrna binding protein selectively binds to the polypyrimidine rich bipartite sequence in the coding region of the lhr mrna and accelerates its degradation . in response to preovulatory lh s...
microbial cells may outnumber our own cells in the body , presenting an example of nature 's intricate evolutionary scheme of host microbe symbiosis ( frank and pace 2008 ; ley et al . this unique setup of human microbe interactions and its resilience is of paramount importance for health . starting from birth ,...
abstracthigh individuality , large complexity and limited understanding of the mechanisms underlying human intestinal microbiome function remain the major challenges for designing beneficial modulation strategies . exemplified by the analysis of intestinal bacteria in a thousand western adults , we discuss key concep...
in 2000 , davison was the first to focus on a relatively common problem after uncomplicated cataract surgery , which was called negative dysphotopsia ( nd ) . this side effect of cataract surgery typically vanishes after a couple of weeks or months and rarely persists for longer periods of time . in most cases it doe...
we present novel clinical observations on negative dysphotopsia ( nd ) in eyes that have undergone cataract surgery . in the past , shadow effects were alleged to be located in the far peripheral temporal visual field 50 to 100 away from the optical axis . in a small series of eight patients we found evidence of phot...
meniscal repairs are likely to have better long - term outcomes than meniscal resections , patients report better functional outcome , and it is assumed that repair is superior to resection in preventing osteoarthritis , even if the healing is not complete . arthroscopic all - inside techniques are often used in p...
purposemultiple techniques and implants are available for all - inside meniscal repair , but the knowledge about their failure rates and functional outcome is still incomplete . the hypothesis was that there might be differences between meniscal arrows and suture devices regarding reoperation rates and functional outco...
lack of suspicion , non - specific clinicoradiological presentation ( often mimicking tuberculosis and fungal infections ) , diagnostic intricacies , and lack of systematic reporting are the probable reasons that have hindered the true estimation of its incidence , worldwide . we present a case series of three patien...
pulmonary nocardiosis is a rising bacterial infection , with a high propensity for misdiagnosis . on account of a paucity of prospective studies , there is limited understanding on various aspects of its diagnosis and treatment . we present three patients with pulmonary nocardiosis , with emphasis on the predisposing...
this was an analytical cross - sectional study of 45 treatment - nave patients with leprosy and 45 patients with other skin diseases as the control group . both groups attended the foundation of tropical dermatology and venereology alfredo da matta ( fuam ) , which is a tertiary reference centre for leprosy treat...
the aim of this study was to investigate sensitivity disorders in the oral cavity related to the presence of mycobacterium leprae in the saliva of treatment - nave patients with leprosy in the state of amazonas , brazil . a cross - sectional study was conducted involving 45 subjects with leprosy . the subje...
although this reported prevalence is true in referral centres , it is probably much lower in the primary care outpatient setting . the importance of secondary hypertension lies in the fact that the hypertension may be remediable on treatment of the underlying cause . there are many conditions that can result in an ...
apart from seeking target organ damage , the investigation of hypertension is primarily aimed at finding a treatable cause of the hypertension . the finding of one such cause is usually construed as being the sole culprit responsible for the patient 's elevated blood pressure . the existence of multiple aetiologies...
dietary supplements and herbal medicines play important roles in health care . vitamins and minerals are important , as they are necessary for enzymatic reactions and bodily functions ; lack of these compounds can lead to deficiency - related diseases . herbal medicine was the predominant form of health care for the ...
backgrounddietary supplements and herbal medicines are gaining popularity in many developed countries.aimsalthough most can be used without any problem , serious toxicities do occur.methodsproblems can be anticipated when they are used for non - traditional indications , at excessive dose , for prolonged duration , or ...
alzheimer 's disease ( ad ) and parkinson 's disease ( pd ) are progressive neurodegenerative disorders for which we do not have a cure . the current drug treatments are more designed to keep the symptoms at bay , but do not repair or prevent further degeneration . there is a clear need for novel treatments , and t...
type 2 diabetes is a risk factor for alzheimer 's disease and parkinson 's disease . insulin signaling in the brains of people with alzheimer 's disease or parkinson 's disease is impaired . preclinical studies of growth factors showed impressive neuroprotective effects . in animal models of alzheimer 's disease an...
voltage - gated potassium channels of the kv1.3 type are widely expressed in many types of cells , both normal and cancer ( felipe et al . activity of kv1.3 channels plays an important role e.g. in setting the resting membrane potential , cell proliferation , apoptosis and volume regulation ( cahalan and chandy 2009 ...
using whole - cell patch - clamp technique , we investigated influence of selected compounds from groups of prenylated chalcones and flavonoids : xanthohumol and isoxanthohumol on the activity of kv1.3 channels in human leukemic jurkat t cells . obtained results provide evidence that both examined compounds were inhi...
hepatocellular carcinoma ( hcc ) is the fifth - most prevalent malignancy worldwide and the second leading cause of cancer - related deaths . more than 700,000 newly diagnosed cases occur every year ; unfortunately , about 7580% of these cases occur in the asian pacific region , and especially in china . hcc is one...
backgroundthe usefulness of des--carboxyprothrombin ( dcp ) has been indicated in areas where hepatitis c virus is prevalent . dcp has yet to be used in china . the aim of this study was to evaluate the usefulness of dcp in chinese patients with hepatocellular carcinoma ( hcc ) predominantly caused by hepatitis b.m...
isolated and unilateral granuloma annulare occurring in clusters on the finger of an adult is rare . it is frequently misdiagnosed as a rheumatoid nodule due to its clinical and histopathological resemblance . a 53-year - old female presented with multiple asymptomatic skin - colored nodules over the right ring fin...
subcutaneous or deep granuloma annulare is a benign asymptomatic condition characterized by firm asymptomatic nodules in deep subcutaneous tissues that may be associated with intradermal lesions . a 53-year - old female presented with asymptomatic skin - colored , firm nodules over the right ring finger . histopath...
intrinsically disordered proteins ( idps ) lack a well - defined three - dimensional structure under physiological conditions of ph and salinity and in the absence of a partner or ligand . some idps however fold , partially or completely , into ordered conformations upon binding to specific interactors . the extrem...
intrinsically disordered proteins ( idps ) exert key biological functions but tend to escape identification and characterization due to their high structural dynamics and heterogeneity . the possibility to dissect conformational ensembles by electrospray - ionization mass spectrometry ( esi - ms ) offers an attractin...
retinitis pigmentosa ( rp ) is a hereditary degenerative disorder characterized by progressive loss of photoreceptor and visual function . the visual field constricts as the disease progresses , eventually leading to severe visual loss in the advanced stage . although visual field testing is used as a standard meth...
purpose . to evaluate the relationship between macular microstructures and visual function in retinitis pigmentosa ( rp ) . method . fourier domain optical coherence tomography ( fd - oct ) and goldmann perimetry were used to examine 100 eyes of 100 rp patients . the preserved photoreceptor outer segment ( pros ) len...
blue shield plan physician participation agreements serve both as a marketing device to attract subscribers and as a short - run cost - containment strategy . in most blue shield plans a participating physician agrees to accept the plan 's allowance for a procedure as payment in full . in return , the physician may be ...
many blue shield plans offer participation agreements to physicians that are structurally similar to the participation provisions of medicaid programs . this paper examines physicians ' participation decisions in two such blue shield plans where the participation agreements were on an all - or - nothing basis . the...
they alter the surrounding extracellular matrix and modify normal cell behavior to facilitate tumor cell growth , invasion , immune evasion , and angiogenesis . most of these effects are mediated by the release of small vesicles from the tumor cells into the extracellular medium . shed vesicles are known to facilit...
expression of sphingosine kinase-1 ( sphk-1 ) correlates with a poor survival rate of tumor patients . this effect is probably due to the ability of sphk-1 to be released into the extracellular medium where it catalyzes the biosynthesis of sphingosine-1-phosphate ( s1p ) , a signaling molecule endowed with profound p...
neuroeconomics is a general framework for studying the neural basis of economic decision making . at first glance , one may wonder how this discipline can be relevant to the sort of issues that neurologists and psychiatrists are concerned with , beyond identifying the causes of pathological gambling or compulsive spe...
choice behavior requires weighing multiple decision variables , such as utility , uncertainty , delay , or effort , that combine to define a subjective value for each considered option or course of action . this capacity is based on prior learning about potential rewards ( and punishments ) that result from prior act...
su was involved in the care of the patient , performed literature search and drafted the manuscript .
key clinical messageit is important to recognize that congenital double pylorus is a benign condition , so that extensive workup can be avoided . also , endoscopists should be aware of the double pylorus and demonstrate extra caution during endoscopic retrograde cholangiopancreatography ( ercp ) .
occidental diet is characterized by high caloric intake , mainly saturated fatty acids and glucose consumption , contributing to the development of obesity and insulin resistance . in the past 15 years , obesity has been associated to chronic inflammation in several tissues and cells , such as liver , adipose tissue ...
high consumption of polyunsaturated fatty acids , such as sunflower oil has been associated to beneficial effects in plasma lipid profile , but its role on inflammation and insulin resistance is not fully elucidated yet . we evaluated the effect of sunflower oil supplementation on inflammatory state and insulin resis...
hepatitis b virus ( hbv ) infection is a common disease that can induce a chronic carrier state and is associated with the risk of progressive disease and hepatocellular carcinoma.1 interferon ( ifn ) and several nucleoside / nucleotide analogs ( nas ) , such as lamivudine ( lam ) , adefovir dipivoxil ( adv ) , entecav...
tenofovir disoproxil fumarate ( tdf ) is widely used to treat hepatitis b virus ( hbv ) patients in the usa and europe . no confirmed report of resistance selection during treatment with tdf in treatment - nave and nucleoside / nucleotide analog - treated chronic hepatitis b patients has yet been reported . here , ...
methanol is a colorless and highly toxic organic solvent and is commonly used in industry . subsequently , it is metabolized to formaldehyde by alcohol dehydrogenase , which is in turn converted into formic acid by aldehyde dehydrogenase . it has been reported that formaldehyde stays too transitory to be detected b...
objective . to explore the potential effects of methanol and its metabolite , formic acid , on rat retina function . methods . sprague - dawley rats were divided into 3- and 7-day groups and a control . experimental groups were given methanol and the control group were provided saline by gavage . retinal functi...
campylobacter concisus is a gram - negative bacterium that is commonly present in the human oral cavity [ 1 , 2 ] . in some individuals , c. concisus may colonize the intestinal tract and was found to be associated with inflammatory bowel disease ( ibd ) due to its significantly higher prevalence in the intestinal trac...
campylobacter concisus is an oral bacterium that is associated with intestinal diseases . c. concisus was previously described as a bacterium that requires h2-enriched microaerobic conditions for growth . the level of h2 in the oral cavity is extremely low , suggesting that c. concisus is unlikely to have a microaero...
participation in exercise and regular physical activity can provide numerous physiological , cognitive , and psychological health benefits in the aging population . impairments in fitness components such as muscle strength and balance influence the development of disability . in addition to muscle strength and bala...
introduction . understanding how exercise affects individuals with varying levels of functional ability will provide further insight into the role of exercise during the aging process . it will also aid in the development of exercise programs that are appropriate for a wider spectrum of older adults . specifically ...
pets , especially domestic dogs , provide significant benefits to individuals and to society , since they can contribute to physical , social , and emotional development of children and the wellbeing of their owners ; however , hygiene and dietary habits of the animals make them particularly prone to having a range of ...
canis familiaris is a domestic animal which plays an important role as a pet ; however , it is very likely to develop diseases characterized by high morbidity and mortality . in this sense , there are some ancylostomatidae species that can lead to anemia , weight loss , and abdominal pain . therefore , the treatmen...
for this study , we selected 250 cases diagnosed with b cell lymphomas , t cell lymphomas and reactive lymphadenitis from 2004 - 2012 at chonnam national university hospital ( gwangju , korea ) and chonnam national university hwasun hospital ( hwasun , korea ) . the purity and concentrations of the dna in all cases w...
backgrounda clonality test for immunoglobulin ( ig ) and t cell receptor ( tcr ) is a useful adjunctive method for the diagnosis of lymphoproliferative diseases ( lpds ) . recently , the biomed-2 multiplex polymerase chain reaction ( pcr ) assay has been established as a standard method for assessing the clonality of...
in the pancreas , the cholecystokonin-2 receptor ( cck-2r ) , formerly the cck - b receptor , has been located exclusively on the somatostatin - delta cells of six different species , including man . to date , nothing is known about the role of this cck receptor subtype on the physiology of these delta cells . ...
with the exclusive presence of the pancreatic cck-2 receptors on the pancreatic delta cells of six different species , this study was undertaken to determine the role of cholecystokinin and gastrin on growth of these somatostatin ( ss ) cells . for this study , the ss - rin-14b cells were used in culture and their gr...
parkinson s disease ( pd ) is the second most common neurodegenerative disease behind alzheimer s disease ( ad ) . an essay on the shaking palsy . the cardinal motor signs of pd ( bradykinesia , resting tremor , cogwheel rigidity , postural instability ) are emphasized in making the diagnosis and in tracking progres...
parkinson s disease ( pd ) afflicts millions of people worldwide and leads to cognitive impairment or dementia in the majority of patients over time . parkinson s disease dementia ( pdd ) is characterized by deficits in attention , executive and visuospatial function , and memory . the clinical diagnostic criteria ...
the year 2011 was a banner year for oral health reports ; the institute of medicine published two key reports entitled advancing oral health in america which outlined the seriousness of poor oral health and lack of access in the oral health care system in america . the second report was entitled improving access...
the institute of medicine report called for a greater role for nurses within the context of oral health in two recent publications , advancing oral health in america ( 2011 ) and improving access to oral health care for vulnerable and underserved populations ( 2011 ) . nurses provide care for many vulnerable persons ...
the word autophagy is derived from the greek language auto ( self ) and phagy ( eating ) ( self - eating ) and generally refers to the cell catabolic and recycling processes in which cytoplasm non - essential and old or damaged components are transported to lysosomes for lysosome - mediated degradation and turnover pro...
autophagy is a major intracellular degeneration pathway involved in the elimination and recycling of damaged organelles and long - lived proteins by lysosomes . many of the pathological factors , which trigger neurodegenerative diseases , can perturb the autophagy activity , which is associated with misfolded protein...
dna sequencing continues to decrease in cost with the illumina hiseq2000 generating up to 600 gb of paired - end 100 base reads in a ten - day run . here we present a protocol for community amplicon sequencing on the hiseq2000 and miseq illumina platforms , and apply that protocol to sequence 24 microbial communitie...
, extensions of the key functions are replaced by updating the level set function based on an artificial image that is composed of the diffused image and the original image . the low convergence problem of the classical algorithm is efficiently solved in the proposed approach .
an improved algorithm for the piecewise - smooth mumford and shah functional is presented . compared to the previous work of chan and vese , and choi et al . , extensions of the key functions are replaced by updating the level set function based on an artificial image that is composed of the diffused image and th...
methicillin - resistant staphylococcus aureus ( mrsa ) is frequently resistant to the majority of commonly used antimicrobial agents , including beta - lactam antibiotics , aminoglycosides , macrolides , chloramphenicol , tetracycline , and fluoroquinolones . the prevalence of methicillin resistance is known to be mo...
the bacteriological efficacy response ( improved , arbekacin vs. vancomycin ; 71.2% vs. 79.5% ) and clinical efficacy response ( improved , arbekacin vs. vancomycin ; 65.3% vs. 76.1% ) were not statistically different between the two groups . the complication rate was significantly higher in the vancomycin group ( 32...
the workshop leaders will present a panoramic view of the community mental health care in holland : some figures of psychiatric disorders , organizational features of mental health care , treatment of depression and anxiety disorders in primary health care , treatment and care of the severe mentally ill and public ment...
short description of the workshopthe workshop leaders will present a panoramic view of the community mental health care in holland : some figures of psychiatric disorders , organizational features of mental health care , treatment of depression and anxiety disorders in primary health care , treatment and care of the se...
the zebrafish has become an attractive model for human disease modeling as there are a large number of orthologous genes in the zebrafish genome , and the encoded proteins exhibit similar functions to those expressed in humans . the methods that are available to manipulate zebrafish gene expression are limited , but ...
the zebrafish ( danio rerio ) has become an attractive model for human disease modeling as there are a large number of orthologous genes that encode similar proteins to those found in humans . the number of tools available to manipulate the zebrafish genome is limited and many currently used techniques are only effec...
many enzymes are activated by specific binding of one or more monovalent cations ( mvcs ) ; these either contribute directly to the catalysis at the active site or indirectly modulate the activity by binding to an allosteric site . potassium and sodium ions are the most common activating mvcs , with a strong correlat...
a variety of enzymes are activated by the binding of potassium ions . the potassium binding sites of these enzymes are very specific , but ammonium ions can often replace potassium ions in vitro because of their similar ionic radii . in these cases , ammonium can be used as a proxy for potassium to characterise pot...
dyadic contests for limited resources are common in animals ( huntingford and turner 1987 ; hardy and briffa 2013 ) . in these contests , asymmetrical fighting ability and/or resource holding potential ( rhp ; parker 1974 ) are among the most important factors that determine outcomes . since rhp is often determined...
in dyadic contests , theoretical studies have predicted that weaker contestants are less likely to engage in fights to minimize the cost of aggression . since the major cheliped of decapod crustaceans is critically important as a weapon , contestants without a major cheliped should be more likely to give up the conte...
a 63-year - old male patient was submitted to cbct ( i - cat , imaging sciences international , hatfield , pa , usa ) of the mandible for the planning of rehabilitating treatment with dental implants . 1 ) , sequential parasagittal sections obtained every 1 mm in the distomesial direction ( fig . 3 ) revealed the p...
the mental foramen is a bilateral opening in the vestibular portion of the mandible through which nerve endings , such as the mental nerve , emerge . in general , the mental foramen is located between the lower premolars . this region is a common area for the placement of dental implants . it is very important to...
based on numerous studies , sex ratio at birth ( srb , male proportion ) varies with many variables ( james 1987 ; ansari - lari et al . , 2004 ; saadat 2005 , 2008 ; james 2006 , 2009 ; masoudi and saadat 2007 ; saadat and khalili 2009 ) . the subject of changing in srb during or shortly after wars was investigated ...
the main objective of this study was to investigate whether the sex ratio at birth ( srb , male proportion ) alter in iraq during its war against iran ( 1980 - 1988 ) . here we compared 785 births ( 348 males , 437 females ) during 1980 - 1989 with 1144 births ( 655 males , 489 females ) before 1980 and 2914 births (...
several key reactions in a cell involve proteins interacting with the phosphate moiety , either as an isolated phosphate ion or as part of a phosphorylated ligand . the phosphate group has been observed to interact with more than half of the known proteins ( 1 ) . moreover many phosphate binding proteins are involv...
phosfinder is a web server for the identification of phosphate binding sites in protein structures . phosfinder uses a structural comparison algorithm to scan a query structure against a set of known 3d phosphate binding motifs . whenever a structural similarity between the query protein and a phosphate binding mot...
developmental dyslexia ( dd ) , also known as reading disability , is characterized by unexpected difficulties in reading and spelling without apparent intellectual and neurological impairment . notably , it was more prevalent among children with nonsyndromic cleft lip with or without cleft palate ( nscl / p ) , a co...
developmental dyslexia ( dd ) is a neurodevelopment disorder characterized by reading disabilities without apparent etiologies . nonsyndromic cleft lip with or without cleft palate ( nscl / p ) is a structural craniofacial malformation featured by isolated orofacial abnormalities . despite substantial phenotypic diff...
recently , a large number of cardiovascular risk factors have been detected , but the role of new risk factors added to traditional ones in predicting or preventing cardiovascular diseases and mortality is still unknown . homocysteine and lipoprotein a are two new risk factors of heart diseases and may cause plaque f...
background : the purpose of this study was to investigate the effect of 12-week of aerobic training on homocysteine , lipoprotein a and lipid profile levels in sedentary middle - age men.methods:this was a quasi - experimental study . subjects of the study were 24 men ( age 40 - 60 ) who participated is the study vol...
employment in cotton processing industry is associated with exposure to broken cotton fibers , bracts , and pericarps as well as to bacteria and fungi that may grow on cotton products . the classical occupational lung disease associated with cotton industry is byssinosis , an acute and reversible response to cotton d...
the most well - known disease caused by cotton dust is byssinosis though it is also associated with chronic obstructive airways disease , and very rarely , interstitial lung disease . obliterative bronchiolitis has never been reported in this setting . we report a 63-year - old , nonsmoker male , who presented with...
the disease symptoms include increased bone density , short stature , hypoplasia of the mandible , an obtuse mandibular angle , dysplasia of the skull bones with unossified fontanels and separated cranial sutures , partial aplasia of the terminal phalanges , stubby hands and feet with dystrophic nails , spondylolysis o...
abstractobjectivepycnodysostosis is a rare autosomal recessive osteochondrodysplasia resulting from osteoclast dysfunction . growth hormone ( gh ) secretion impairment and low insulin growth factor 1 ( igf - i ) concentrations have been reported in these patients . the present study aims to describe gh effect on li...
it is well known that the content of sea hare digestive glands is derived from the diet that this animal ingests [ 14 ] . a large number of cognate compounds have been isolated from both the red alga of the genus laurencia and the sea hare that preys on the red alga . metabolites isolated from sea hares exhibit var...
the extract of the sea hare , aplysia kurodai , showed cytotoxicity against hela cells and antibacterial activity against staphylococcus aureus . bioassay - guided purification afforded four active compounds , which were identified to be laurinterol , laurinterol acetate , debromolaurinterol , and debromolaurinterol ...
hypertension has been acknowledged as one of the greatest and established risk factors for cardiovascular diseases ( cvd ) ( heart diseases and stroke ) [ 14 ] . particularly in east asian countries , where the mortality and morbidity of stroke have been higher than in western countries , measures against hypertension ...
japan is one of the countries with the longest longevity in the world , and it was accomplished by a drastic decline in stroke mortality from 1960 s . the decline in stroke mortality would be largely explained by a population - wide decreasing trend in blood pressure ( bp ) level , because higher bp has been the stro...
technika przezcewnikowej wymiany zastawki aortalnej zostaa opracowana jako alternatywa dla pacjentw o wysokim ryzyku operacyjnym lub nieoperacyjnych z cik objawow stenoz aortaln . celem niniejszej pracy bya ocena wynikw pacjentw poddawanych przezkoniuszkowej wymianie zastawki aortalnej jako jedynej opcji terapeutyczn...
introductiontranscatheter aortic valve replacement has been developed as an alternative option for surgical high - risk or inoperable patients with severe symptomatic aortic stenosis.aim of the studyaim of the study was to evaluate the outcomes of patients undergoing transapical aortic valve replacement as a single - s...
sedentary behavior , particularly television ( tv ) watching , presents unique risks for obesity and related negative health outcomes in addition to risks from inactivity [ 1 , 2 ] ; even individuals who are very active show increased metabolic risk with higher amounts of tv watching . sedentary video gaming ...
sports- and fitness - themed video games using motion controllers have been found to produce physical activity . it is possible that motion controllers may also enhance energy expenditure when applied to more sedentary games such as action games . young adults ( n = 100 ) were randomized to play three games using e...
regulated spatial and temporal control of gene transcription is a fundamental process for all metazoans . critical to this process is the interaction of transcription factors ( tfs ) with specific cis - regulatory dna sequences . these regulatory sequences for instance , enhancers and promoters are organized in a...
the identification and study of the cis - regulatory elements that control gene expression are important areas of biological research , but few resources exist to facilitate large - scale bioinformatics studies of cis - regulation in metazoan species . drosophila melanogaster , with its well - annotated genome , exce...
diabetes , osteoporosis , chronic liver disease , and coronary artery disease are just some of the common metabolic conditions that affect millions of people , especially later in life . unfortunately , for those infected with hiv , these conditions tend to occur more frequently and at an earlier age compared with t...
genetic screening for hiv - related complications is emerging as a clinically relevant prediction tool . a number of single nucleotide polymorphisms associated with conditions such as dyslipidemia and type 2 diabetes have been identified in both the general population and in hiv - infected individuals . additionally ...
in adults , routine injections of botulinum toxin are the treatment of choice for the management of essential blepharospasm [ 1 , 2 ] . the clinical picture is characterized by recurrent involuntary spasms in the region of the orbicularis oculi muscle . typically , at the time of the first manifestation , the patient...
botulinum toxin injections are the treatment of choice for the management of essential blepharospasm in adults . no cases of congenital blepharospasm have been described in the literature so far , and no cases of botulinum toxin injection in an infant have been reported . a 4-week - old girl was referred to our dep...
conventional phenolics are cross - linked products of low molecular weight precursors , typically formed through a condensation reaction . the versatility of their structures and the fact that they display desirable properties such as good heat resistance , flame - retardant properties , low dielectric cons...
three bis - benzoxazine monomers based on the aniline derivatives of bisphenol a ( ba - a ) , bisphenol f ( bf - a ) , and 3,3-thiodiphenol ( bt - a ) are examined using a variety of spectroscopic , chromatographic , and thermomechanical techniques . the effect on the polymerization of the monomers is compare...
the international diabetes federation estimated the prevalence of diabetes mellitus in spain to be approximately 10.4% , with around 3.6 million adults diagnosed with diabetes and 1.3 million undiagnosed in 2015 . the disease is a considerable burden on spanish patients and , in 2015 , diabetes mellitus was ranked ...
introduction glucagon - like peptide-1 ( glp-1 ) receptor agonists are used successfully in the treatment of patients with type 2 diabetes as they are associated with low hypoglycemia rates , weight loss and improved glycemic control . this study compared , in the spanish setting , the cost - effectiveness of liraglu...
non - communicable diseases ( ncd ) killed 38 million people globally in 2012 , accounting for 68% of total annual death ; and cardiovascular diseases alone were responsible for 17.5 million deaths in the year . the global prevalence of high blood pressure in adults is approximately 22% , and high blood pressure is e...
backgroundadolescent obesity and hypertension are global public health issues . the burden of adolescent obesity and hypertension in peru is unclear . the aim of this study was to determine the prevalence of obesity and hypertension and their relationship among school - attending adolescents and to assess the need ...
serum calcium concentrations are maintained in the normal range until very late in chronic kidney disease ( ckd ) when it decreases slightly ( 1,2 ) . gastrointestinal ( gi ) calcium absorption has been shown to be lower in ckd subjects on normal calcium intake than in controls yet remains dependent on calcium intake...
calcium balance in chronic kidney disease is poorly understood since its deficiency is a stimulus for secondary hyperparathyroidism and consequent bone loss while calcium excess promotes extra - osseous calcifications . to help resolve this , we evaluated calcium balance in normal individuals and in patients with chron...
it poses an important public health challenge to both economically developing and developed countries , including asia . the prevalence and rate of diagnosis of hypertension in children and adolescents appears to be increasing . hypertension confers the highest attributable risk to deaths from cardiovascular diseas...
context : hypertension in youth is increasing , but there is a dearth of data about the knowledge of risk factors in this age group.aims:to assess the knowledge of risk factors of hypertension among university students and associate it with the blood pressure , physical activity , family history of cardiovascular disea...
there are 30 cases reported in the literature between 1982 and 2010 on brain - dead pregnant women whose somatic non - neurological functions were maintained successfully to facilitate fetal maturation in the uterus . however , of the cases reported , 12 viable infants were born and survived the neonatal period . bas...
there are increased reports in the medical literature of brain death during pregnancy . in these rare cases , the decision was either to consider discontinuing homeostatic support and mechanical ventilation with an understanding that the fetus then will also die , or to continue full support in an attempt to prolong ...
a 45 year - old male patient came to the hospital to receive tympanoplasty for chronic otitis media . the patient was 66.6 kg and 164 cm tall , and all physical and general examination results were normal other than the ventricular bradycardia of 58 beats per minute in the ecg . glycopyrrate ( 0.2 mg ) was i m inje...
we report that intraoperative nim-2 monitoring devices can interfere with bispectral index monitoring . a 45-year - old male with chronic otits media underwent tympanolasty under general anesthesia with nim-2 monitoring and bispectral index monitoring at our institution . and then , bispectral index monitoring was se...
diabetes mellitus is a leading cause of mortality and increased disability - adjusted life years ( dalys ) worldwide . in 2010 , an estimated 1.3 million diabetes - related deaths occurred worldwide , which was twice as many as occurred in 1990 . furthermore , the dalys from diabetes increased by 30% during this sa...
diabetes mellitus is a leading cause of mortality and increased disability - adjusted life years worldwide . in korea , the prevalence of diabetes increased from 8.6% to 11.0% in 2001 to 2013 and the prevalence of adult obesity , which is the most important risk factor of diabetes , increased from 29.2% to 31.8% duri...
regional myocutaneous pedicle flaps ( rmf ) are known to be relevant in the reconstruction of major head and neck oncologic defects with pectoralis major myocutaneous pedicle flap ( pmmc ) being the best - known rmf . for over three decades , since first described by ariyan in 1979 , pmmc has continually been used in...
background : pectoralis major myocutaneous pedicle flap and other regional myocutaneous pedicle flaps ( rmf ) , despite the superiority shown by free flaps , have remained relevant in the reconstruction of major head and neck oncologic defects . it has continued to find relevance as the preferred reconstruction of ch...
the abo blood group , which was discovered at the beginning of the 20 century by karl landsteiner remains the most important blood group clinically ( 13 ) . in 1924 , this blood group was classified into four antigens ( a , b , o and ab ) and six genotypes ( aa , ao , bb , bo , oo and ab ) . it is one of the conventi...
abo genotyping is commonly used in several situations , including blood transfusion , personal identification and disease detection . the present study developed a novel method for abo genotyping , using loop - mediated isothermal amplification ( lamp ) . this method allows the simultaneous determination of six abo...
postoperative morbidity and mortality , especially in cancer patients , have been reviewed in a number of studies in the field of gynecology . morbidity after gynaecological surgery ranges from approximately 10% to 20% , whereas mortality is extremely rare . clinical guidelines and recommendations based on the unus...
introductionthe purpose of this study was to note potential gynaecological risk factors leading to intensive care and to estimate the frequency , costs and outcome of management.materials and methodsin a cross - sectional study of intensive care admissions in kuopio from march 1993 to december 2000 , 23 consecutive gyn...
stressful situations are not uncommon in everyday life , experienced for example by a doctor in the emergency room , a police officer in action , or a financial trader on a london trading floor . individuals sometimes need to make important decisions when the stakes are high and when not enough information or cogniti...
humans often make decisions in stressful situations , for example when the stakes are high and the potential consequences severe , or when the clock is ticking and the task demand is overwhelming . in response , a whole train of biological responses to stress has evolved to allow organisms to make a fight - or - flight...
note : in order to minimize pcr carryover contamination , it is important to keep several important key steps in the pcr physically - separate from one another : 1 ) template ( dna ) preparation , 2 ) pcr setup , and 3 ) gel electrophoresis . it is also recommended to use barrier tips in order to prevent culture or r...
current commercial pcrs tests for identifying salmonella target genes unique to this genus . however , there are two species , six subspecies , and over 2,500 different salmonella serovars , and not all are equal in their significance to public health . for example , finding s. enterica subspecies iiia arizona on a...
a systematic literature search was conducted in september 2013 . to find all articles describing experimental huts , the following databases were searched : pubmed ( national center for biotechnology information , national library of medicine , national institutes of health ) , the armed forces pest management ...
the physical integrity of bednets is a concern of national malaria control programs , as it is a key factor in determining the rate of replacement of bednets . it is largely assumed that increased numbers of holes will result in a loss of protection of sleepers from potentially infective bites . experimental ...
we have previously found that multistep renal carcinogenesis occurs in eker rats8 and reported that erc , a rat renal carcinoma gene , is highly expressed in renal cancer.9 rat erc is a homolog of the human mesothelin gene10 , 11 that is localized to chromosome 16p13.3.12 mesothelin is expressed in normal mesothelial c...
asbestos is an environmental carcinogen , and asbestosrelated diseases represent a globalscale environmental issue . mesothelioma is an aggressive , malignant tumor that initially progresses along the surfaces of the pleura and peritoneum that is chiefly attributed to asbestos exposure . xrays are commonly used for...
gattii species complex , which is composed of two separate species , c. neoformans and c. deneoformans , and five species within c. gattii . the most clinically relevant complex species were recently revised based on phenotypic and genotypic diversity , supported by the presence of distinct and consistent lines ,...
in egypt , the river red gum ( eucalyptus camaldulensis ) is a well - known tree and is highly appreciated by the rural and urban dwellers . the role of eucalyptus trees in the ecology of cryptococcus neoformans is documented worldwide . the aim of this survey was to show the prevalence of c. neoformans during the ...
gastrointestinal ( gi ) bleeding is a common emergency and bleeding from the upper gi tract and small intestine account for 75% and 210% of all gi bleeds , respectively . we describe a 29-year - old man who presented with obscure anemia due to small intestine bleeding . vascular abnormalities account for 7080% ...
the source of most cases of gastrointestinal bleeding is the upper gastrointestinal tract . since bleeding from the small intestine is very rare and difficult to diagnose , time is required to identify the source . among small intestine bleeds , vascular abnormalities account for 7080% , followed by small intestine t...
various methods , such as allografting [ 1 , 2 ] , pasteurized autografting , and bone elongation , have recently been employed for the reconstruction of limbs affected by malignant bone tumors . tumor prosthesis use is advantageous in that it facilitates stable function of the affected limb and an early return to so...
backgroundamong 40 patients with primary malignant tumors of the knee joint who underwent reconstruction of the affected limb with tumor prosthesis , revision was required in 7 due to stem breakage or loosening.subjects and methodsin the 7 cases undergoing revision , conditions and background factors at the time of bre...
secondary organic aerosol ( soa ) , formed in situ from the conversion of gas - phase volatile organic compounds ( vocs ) to oxidized products that partition preferentially to the particle phase , is an important source of aerosol mass both regionally and globally . it is estimated that approximately 70% of...
the secondary organic aerosol ( soa ) mass yields from no3 oxidation of a series of biogenic volatile organic compounds ( bvocs ) , consisting of five monoterpenes and one sesquiterpene ( -pinene , -pinene , -3-carene , limonene , sabinene , and -caryophyllene ) , were investigated in a series of continuous f...
the term " idc - p " was first used in 1973 and later defined as a heterogeneous group of tumors , including urothelial carcinoma , squamous cell carcinoma , and prostatic ductal and acinar carcinomas , extending into normal prostatic ducts and acini.8,9 kovi et al.10 were the first group to intensively study intraduct...
intraductal carcinoma of the prostate ( idc - p ) is defined as a proliferation of prostate adenocarcinoma cells distending and spanning the lumen of pre - existing benign prostatic ducts and acini , with at least focal preservation of basal cells . studies demonstrate that idc - p is strongly associated with high - ...
modern science through improved sanitation , vaccination , antibiotics and medical attention has eliminated the threat of death from most infectious diseases . but now , too many people are dying relatively young from noncommunicable diseases like heart diseases and cancer . the main contributing factor for this ep...
background : several health - compromising behaviors ( e.g. , smoking , alcohol ) as well as health - enhancing behaviors ( e.g. , physical exercise , nutrition ) are adopted in adolescence and they often persist into adulthood . thus , there is a definite need to investigate the health behavior of adolescents rather t...
functional obstruction and bowel dilatation proximal to the affected segment , first described by harald hirschsprung in 1888 , is a complex disorder resulting from absence of ganglion cells in the bowel wall leading to functional obstruction and bowel dilatation proximal to the affected segment [ 1 , 2 , 3 ] . it is...
objectivehirschsprung 's disease ( hd ) is a complex disorder resulting from absence of ganglion cells in the bowel wall leading to functional obstruction and bowel dilatation proximal to the affected segment . the aim of our study was to evaluate rectal biopsies from constipated children in different age groups to s...
malignant tumors , most often originating in the lung and breast , occasionally metastasize to intraocular structures . most intraocular metastases occur in the uveal tract ( iris , ciliary body , and choroid ) . in a study of 520 eyes with uveal metastases , only 8% occurred in the iris among 950 metastatic lesions ...
we report a case of isolated iris metastasis from esophageal adenocarcinoma that was successfully managed with local application of stereotactic body radiation therapy ( sbrt ) and adjunctive intravitreal therapy . a 53-year - old man with locally advanced esophageal adenocarcinoma achieved a complete clinical and ra...
methylmalonic acidemia ( mma ) is an inborn error of metabolism caused by deficiency of the mitochondrial enzyme , methylmalonyl - coa mutase ( mut ) . this vitamin b12 dependent enzyme catalyzes the isomerization of l - methylmalonyl - coa into succinyl - coa at the terminal step of propionyl - coa oxidation . iso...
purposewe sought to predict renal growth based on clinical and metabolic parameters in patients with isolated methylmalonic acidemia ( mma ) , a group of disorders associated with chronic kidney disease.methodsfifty mma patients , followed from 2004 to 2011 , were classified by molecular genetics and studied using a co...
it is usually manifested by neurological syndromes such as tetraparesis , paraparesis or brown - sequard syndrome . sceh presenting with pure motor hemiparesis is extremely rare , and may be mistaken for cerebrovascular stroke . although magnetic resonance imaging ( mri ) is generally considered to be the most reliab...
abstracta spontaneous cervical epidural hematoma ( sceh ) is a rare condition , which usually requires urgent treatment . however , unusual manifestations , such as hemiparesis , may lead to a misdiagnosis . we herein report a case of sceh that presented with pure motor hemiparesis to discuss the appropriate and pr...
variable ( v ) , diversity ( d ) and joining ( j ) ( v(d)j ) recombination of antigen receptor ( agr ) loci is the first step in generating the diverse agr repertoires that enable the adaptive immune system to respond to a vast array of pathogens and regulate tissue homeostasis and surveillance . this process , which...
summaryvariable ( v ) , diversity ( d ) , and joining ( j ) ( v(d)j ) recombination is the first determinant of antigen receptor diversity . understanding how recombination is regulated requires a comprehensive , unbiased readout of v gene usage . we have developed vdj sequencing ( vdj - seq ) , a dna - based next ...
it is estimated that in 2015 the number of new cancer cases and deaths due to cancer will be 15 million and 9 million per year , respectively . cervical cancer is the third most common cancer and the fourth leading cause of cancer death in women worldwide . the primary cause of this cancer is infection with human ...
abstractbackground : although the pap smear is known as one of the effective methods to detect the cervical cancer , a large group of women are reluctant to do the test because of various reasons . therefore , we carried out this study to determine the level of knowledge about cervical cancer and pap smear and the fa...
visualization of protein domain architecture and highlighting the presence of protein domains conserved in molecular evolution have become de facto standards in protein sequence analysis and are routinely provided by protein information resources . a conserved domain footprint may reveal aspects of a protein 's molec...
ncbi 's conserved domain database ( cdd ) is a collection of multiple sequence alignments and derived database search models , which represent protein domains conserved in molecular evolution . the collection can be accessed at http://www.ncbi.nlm.nih.gov/structure/cdd/cdd.shtml , and is also part of ncbi 's entrez q...
recently , transcriptomic data from dna microarrays have allowed researchers to analyze gene expression and explore the molecular basis of disease . analysis of the transcriptome allows researchers in oncology to study the regulatory mechanisms and biochemical pathways involved in cell transformation and tumor progre...
transcriptome microarrays have become one of the tools of choice for investigating the genes involved in tumorigenesis and tumor progression , as well as finding new biomarkers and gene expression signatures for the diagnosis and prognosis of cancer . here , we describe a new database for integrated tumor transcriptome...
infectious diseases are the second - leading cause of death worldwide and cause significant morbidity . a factor contributing to the prevalence of infectious disease has been the development and spread of resistance to current antibiotics ( 1 ) . despite this alarming trend , research into traditionally , antibioti...
abstractantivirulence drugs disarm rather than kill pathogens and are thought to alleviate the problem of resistance , although there is no evidence to support this notion . quorum sensing ( qs ) often controls cooperative virulence factor production and is therefore an attractive antivirulence target , for which inh...
psychopathy is a personality disorder in which some of the defining features include being manipulative , callous , and impulsive . despite an abundance of research , the disorder is costly to society , as individuals with psychopathy continuously rotate through the criminal justice system ( hare , 1999 ) . individ...
individuals with psychopathy possess emotional and behavioral abnormalities . two neural regions , involved in behavioral control and emotion regulation , are often implicated : amygdala and ventromedial prefrontal cortex ( vmpfc ) . recently , in studies using adult criminal populations , reductions in microstruct...
a new method for treating dental caries that involves no drill , running water or electricity was presented at the headquarters of the world health organization on world health day in 199412 . this approach , called " atraumatic restorative treatment " ( art ) consists of manually cleaning dental cavities with hand i...
objective : the purpose of this study was to investigate the clinical performance of high - strength glass ionomer cement ( hsgic ) and resin - modified glass ionomer ( rmgic ) in single and multiple surface carious cavities in the field conditions.material and methods : a split - mouth design , including ninety - one ...
among 178 ( out of 195 ) countries that responded to a recent global low vision services survey , low vision services were reported to be present in 115 ( 64% ) countries . however , presence of services does not necessarily equate to good coverage of services . of the 115 countries with low vision services , 39 coun...
two - thirds of the world 's population with low vision resides in the asia - pacific region . provision of comprehensive low vision services is important to improve vision - related quality of life ( qol ) for people with this condition . this review outlines the critical issues and challenges facing the provision...
antenatal care ( anc ) is a careful , systematic assessment and follow - up of pregnant women , that includes education , counseling , screening , and treatment to assure the best possible health of the mother and her fetus.1 the anc program was designed in europe in the first decades of the 20th century and was first ...
the aim of health education during antenatal is to provide advice , education , reassurance and support , to address and treat the minor problems of pregnancy , and to provide effective screening during the pregnancy . exploring current practices in this regard revealed the need for more organized educational activit...
thirty - three diverse oral drugs were tested for colloid formation in biochemical buffers ( figure 1 ) . we chose low solubility drugs with high clogp values , as they are more prone to aggregation than high solubility drugs.(15 ) we also tested methylene blue , a dye used in several clinical indications and now in ...
many organic molecules form colloidal aggregates in aqueous solution at micromolar concentrations . these aggregates promiscuously inhibit soluble proteins and are a major source of false positives in high - throughput screening . several drugs also form colloidal aggregates , and there has been speculation that th...
the brain processes information from the external world and creates neuronal representations of the environment that change in response to sensory experience . the extent to which environmental stimuli modify brain structure and function has been extensively studied in the visual system . visual cortical circuitrie...
the central nervous system architecture is markedly modified by sensory experience during early life , but a decline of plasticity occurs with age . recent studies have challenged this dogma providing evidence that both pharmacological treatments and paradigms based on the manipulation of environmental stimulation le...
nineteen of 63 patients , operated in a high - volume cataract surgery setting at a nearby hospital were referred to us with acute onset of redness and decreased vision . at admission , all patients underwent slit - lamp examination , applanation tonometry , dilated fundus evaluation and b - scan ultrasonography . ...
we report a case series of endophthalmitis by an organism hitherto not reported in the eye . nineteen of 63 cataract patients operated in a high - volume setup were urgently referred to us with acute onset of decreased vision one to two days following cataract surgery . all patients had clinical evidence of acute e...
fibro - osseous lesions ( fol ) of the jaws constitute a group of conditions which are remarkable for their clinico - pathological similarities . they differ , with the exception of fibrous dysplasia , from those found in the rest of the skeleton . fols of the face and jaws include ossifying fibroma , fibrous dysplas...
central ossifying fibroma is a rare , benign fibro - osseous lesion that arises from the periodontal ligament . periapical cemento - osseous dysplasia is another variant of fibro - osseous lesion which occurs in the anterior region of the mandible of females . odontoma is a benign odontogenic tumor that contains en...
we assigned 1,791 veterans at 20 va medical centers who had a suboptimal response to therapy for type 2 diabetes to receive either intensive or standard glucose control . the primary outcome was the time from random assignment to the first occurrence of a major cardiovascular event . strict control of blood pressur...
objectivethe veterans affairs diabetes trial ( vadt ) was a randomized , prospective , controlled trial of 1,791 patients with type 2 diabetes to determine whether intensive glycemic control would reduce cardiovascular events compared with standard control . the effect of intensive glycemic control and selected basel...
airway management is a core skill in emergency medicine , anesthesiology , and critical care . ensuring an unobstructed airway and adequate oxygenation are first priorities in the resuscitation of the patient . unlike the elective surgical patient , the trauma and critically ill patients present with many challenges . ...
background : various anatomical measurements and noninvasive clinical tests , singly or in various combinations can be performed to predict difficult intubation . upper lip bite test ( ulbt ) and ratio of height to thyromental distance ( rhtmd ) are claimed to have high predictability . hence , we have conducted th...