article stringlengths 0 826k | abstract stringlengths 174 4.34k |
|---|---|
rectal foreign bodies can present a difficult management dilemma , because the types encountered vary widely and they can cause not only local trauma to surrounding tissues but also obstruction or perforation that requires surgical treatment . for effective removal , it is important to precisely determine the size , sh... | we occasionally encounter patients with various types of rectal foreign bodies .
when too large to grasp , transanal removal can be difficult . here , we report a case of successful manual transanal removal of an 18 4 4 cm silicon rod without complications .
a 50-year - old male came to the emergency department o... |
functional magnetic resonance imaging ( fmri ) studies in chronic pain patients have the potential to provide valuable information about the neural mechanisms and efficacy of analgesic therapies , including drug treatments , acupuncture , brain stimulation , distraction tasks , mindfulness meditation , and cognitive - ... | as the practice of conducting longitudinal fmri studies to assess mechanisms of pain - reducing interventions becomes more common , there is a great need to assess the test retest reliability of the pain - related bold fmri signal across repeated sessions .
this study quantitatively evaluated the reliability of heat... |
the geriatric population , defined as people over the age of 65 , comprised 6.2% of the world population in 1992 and is estimated to reach 20% by 2050 .
aging is associated with numerous chronic illnesses and comorbid conditions [ 2 , 3 ] , polypharmacy and immunosuppressive medications , and changes in the immune sy... | introduction . infectious diseases may present with atypical presentations in the geriatric patients .
while fever is an important finding of infections , it may also be a sign of noninfectious etiology .
methods . geriatric patients who were hospitalized for acute fever in our infectious diseases unit
were inc... |
the present study examines the dose - response relationship for 2,3,7,8-tetrachlorodibenzo - p - dioxin ( tcdd ) promotion of histologic and biochemical parameters by using a two - stage model for hepatocarcinogenesis in female sprague - dawley rats initiated with a single intraperitoneal dose of 175 mg of diethylnitro... | |
obesity elevates the risk of developing a number of diseases , including atherosclerosis , diabetes , nonalcoholic fatty liver disease , certain cancers , and immune - mediated disorders such as asthma [ 13 ] .
there is also converging evidence that negative mood states and stress create susceptibility to physica... | objective . two major causes of disability ,
major depression and obesity , share overlapping psychosocial and pathophysiological etiologies .
studies are now focused on biological mechanisms linking the two illnesses , and there is interest in the role that adipokines may have in mediating the association between ... |
development of renal replacement therapies such as hemodialysis ( hd ) , peritoneal dialysis ( pd ) and renal transplantation in children with end - stage renal disease ( esrd ) has resulted in improved long - term survival1 ) . however , esrd influences virtually every organ system and thus , has a major impact not on... | quality of life in addition to various medical problems in children with end - stage renal disease ( esrd ) should be objectively assessed to accomplish normal growth and development during childhood . however , unfortunately , studies of quality of life ( qol ) in children with esrd have been not popular yet and there... |
retrograde urethrogram ( rgu ) and voiding cystourethrogram ( vcug ) are used to define the length and location of urethral stricture prior to surgery . in patients with pelvic fracture urethral distraction defect ( pfudd ) , the bladder neck sometimes fails to open on vcug , leading to erroneous estimation of the stri... | background : retrograde urethrogram and voiding cystourethrogram are used to define length and location of urethral stricture prior to surgery .
we used a single dose of silodosin prior to vcug to relax the bladder neck and achieve visualization of posterior urethra.objectives:to evaluate the efficacy of silodosin in... |
at the end of december 1993 and also at the end of january 1995 , the river meuse , one of the major rivers in europe , flooded and river banks were inundated .
we investigated the possible health risks of exposure to heavy metal concentrations in river bank soils resulting from the flooding of the river meuse at the... | |
deprotonation typically takes place exclusively at the carbon atom to yield carbanions that can be considered acrolein acyl carbanion equivalents .
the presence of the allene function in the products of nucleophilic addition of carbanions such as 1 and 2 confers reactivity due to the strain inherent in the allene , ... | a combined computational and 13c nmr study was used to investigate the formation of mixed aggregates of 1-methoxyallenyllithium and lithium chloride in tetrahydrofuran ( thf ) solution .
the observed and calculated chemical shifts , as well as the calculated free energies of mixed aggregate formation ( mp2/6 - 31+g(d... |
the ability to three - dimensionally interweave biological tissue with functional electronics could enable the creation of bionic organs possessing enhanced functionalities over their human counterparts .
conventional electronic devices are inherently two - dimensional , preventing seamless multidimensional integrati... | |
iliotibial band ( itb ) friction syndrome is a common overuse injury typically seen in runners , cyclists , and military recruits ( 1 ) . magnetic resonance imaging ( mri )
can show the characteristic imaging findings ( 2 ) . however , coincidental findings or other accompanying mass lesions on mri have been rarely r... | iliotibial band ( itb ) friction syndrome is a common overuse injury typically seen in the active athlete population .
a nodular lesion on the inner side of the itb as an etiology or an accompanying lesion from friction syndrome has been rarely reported . a 45-year - old male presented with recurrent pain and a movab... |
anemia continues to be a major public health problem worldwide . according to estimates from the world health organization , two billion individuals suffer from anemia in the world.the highest prevalence of anemia exists in the developing world where its causes are multifactorial , ranging from micronutrient deficienci... | background : the most common cause of anemia is an iron deficiency ; however , the condition may also be caused by deficiencies in folate , vitamin b12 and protein .
some anemia is not caused by nutritional factors , but by congenital factors and parasitic diseases such as malaria.aim:this study attempted to estimate... |
atrial electromechanical delays ( aemds ) are defined as the time intervals between the atrial electrical depolarization and the initiation or peak of atrial mechanical contraction .
it has been shown that prolonged aemds can be used as markers to discriminate patients with paroxysmal atrial fibrillation ( paf ) from... | background and objectivesprevious studies have evaluated atrial electromechanical delays ( aemds ) with a number of different definitions to discriminate patients with paroxysmal atrial fibrillation ( paf ) from controls without paf . however , their discriminative values for paf have not previously been directly compa... |
we report the case of a 58-year - old woman with intracranial hemorrhage associated with stress - induced cardiomyopathy .
left ventricular dysfunction was confined to midventricular segments , and manifested with transient anterolateral wall aneurysm .
although wall motion was severely impaired in the mid - segmen... | introduction : we report the case of a 58-year - old woman with intracranial hemorrhage associated with stress - induced cardiomyopathy.results:left ventricular dysfunction was confined to midventricular segments , and manifested with transient anterolateral wall aneurysm .
although wall motion was severely impaired ... |
aids - related stigma is formed in social environment . the circumstances in which the patients live l.is likely to internalize the stigmatized attitude in them .
according to unaids ( 2000 ) , in the developing world , the stigma and discrimination is a social and cultural phenomenon which is associated with interac... | background : despite the success of developed countries in preventing the spread of hiv / aids , the disease is expanding in developing countries where an unfavorable attitude exists among people , health professionals and employees .
this study aimed to assess the stigmatized attitude among health care providers tow... |
a 67-year - old male patient had undergone esophagectomy and intrathoracic esophagogastrostomy for carcinoma of the lower thoracic esophagus 27 months earlier .
the original pathologic condition was determined to be moderately differentiated squamous cell carcinoma invading the lamina propria without lymph node metas... | we report a very rare case of surgery on gastric conduit cancer .
a 67-year - old male patient underwent esophagectomy and intrathoracic esophagogastrostomy for squamous cell carcinoma of the lower thoracic esophagus 27 months ago . upon follow - up
, a gastric carcinoma at the intra - abdominal part of the gastric... |
a 25-year - old female patient who earlier had implant placement in relation to 46 and 47 reported to our department for second stage surgery .
1994 , in which the attached mucosa at the top of the ridge is moved in a buccal direction at second stage surgery to obtain a papilla like formation and increased bulk of ti... | peri - implant plastic surgery aims at improving the esthetic aspects of smile and masticatory function . over the years
, several techniques such as tissue punch technique , full thickness flaps , and scalloping adjustment of flaps around implants have been employed ; it was very difficult to achieve a papilla like ... |
we sequenced 8 melanoma exomes to identify novel somatic mutations in metastatic melanoma .
focusing on the map3k family , we found that 24% of melanoma cell lines have mutations in the protein - coding regions of either map3k5 or map3k9 .
structural modelling predicts that mutations in the kinase domain may affect... | |
type 1 insulin - dependent diabetes is the most common endocrine and metabolic disorders during childhood and adolescence which greatly influences both the physical and emotional development of individuals and have some long term complications such as nephropathy , neuropathy and retinopathy . according to the latest f... | background : these days , diabetes is deemed as one of the most important health and social - economic problems of the world .
since parents play a major role in treatment of diabetes , the most important part of managing diabetes is in the hands of the parents of children affected by diabetes .
this special respon... |
the incidence of prostate cancer in japan has been increasing in recent years . radiation therapy ( rt )
has been playing an important role in the curative treatment of prostate cancer , because recent novel rt techniques , such as intensity - modulated radiotherapy ( imrt ) , stereotactic radiotherapy , and particle... | the purpose of this study was to determine the risk factors for rectal bleeding after prostate brachytherapy . between april 2005 and september 2009 ,
89 patients with t1c-2cn0m0 prostate cancer were treated with permanent i-125 seed implantation alone .
the prostate prescription dose was 145 gy , and the grade of ... |
atherosclerosis is a chronic inflammatory disease , which involves vascular cells , immune system , and several organs .
although leukocytes , endothelial and smooth muscle cells have been shown to play a crucial role in atherosclerotic inflammation , recent evidence also supports a direct activity for the liver , lu... | recent evidence shows that the renin - angiotensin system is a crucial player in atherosclerotic processes .
the regulation of arterial blood pressure was considered from its first description of the main mechanism involved .
vasoconstriction ( mediated by angiotensin ii ) and salt and water retention ( mainly due ... |
the incidence has been estimated to be 2.5 - 5 per 100000 people per year with a prevalence of 35 per 100000 ( 1 ) .
neuroendocrine cervical carcinoma is a rare subtype of cervical cancer with a high proliferation rate and a marked propensity for regional lymph node metastases and distant metastases , which is simila... | objectiveneuroendocrine cervical carcinoma is a rare subtype of cervical cancer .
these tumors exhibit an aggressive behavior with early regional lymph node and distant metastases .
the purpose of our study was to describe five cases of neuroendocrine cervical - vaginal carcinoma and to discuss the potential of the... |
switches between different phenotypes and their underlying states of gene transcription occur as cells respond to intrinsic developmental cues or adapt to changing environmental conditions .
post - translational modification of the master regulatory transcription factors that define the initial phenotype is a common ... | |
t2 dm is one of the most prevalent chronic diseases worldwide and accounts for 9095% of all diabetes cases .
it encompasses individuals who have insulin resistance and usually have relative rather than absolute insulin deficiency .
however , the underling mechanism of t2 dm is poorly understood , and the present pr... | backgroundat present , whether human cytomegalovirus ( hcmv ) infection is associated with type 2 diabetes mellitus ( t2 dm ) is debatable .
the effect of active hcmv infection on glucose regulation has been poorly studied .
although hcmv infection is correlated with atherosclerosis in cardiovascular disease , the ... |
distance between two genes was defined as the number of base pairs between their gene midpoints .
relative distance refers to the distance of a tsg or a noncancer gene from an oncogene divided by the radius distance .
the gene labels were randomly shuffled 10,000 times to generate new positions of oncogenes , tsgs ... | abstractfocal copy number gains or losses are important genomic hallmarks of cancer .
the genomic distribution of oncogenes and tumor - suppressor genes ( tsg ) in relation to focal copy number aberrations is unclear .
our analysis revealed that the mean distance of tsgs from oncogenes was significantly shorter tha... |
it is incidentally found in autopsy specimens and surgical specimens with cryptorchidism and testicular germ cell tumor .
this non - neoplastic lesion is usually seated in the mediastinum and septal part of the rete testis .
it may present as a very small lesion detected in microscopic examination or a solid - cyst... | there are several tumor - like lesions and miscellaneous neoplasms of the rete testis .
we present a case with adenomatous hyperplasia of the rete testis ( ahrt ) .
the patient was 24 years old with undescended testis and was referred to our hospital .
there were no clinical or endocrine abnormalities .
cryptor... |
non - steroidal anti - inflammatory drugs ( nsaids ) are one of the most commonly prescribed drugs in the world for their analgesic and anti - inflammatory properties . however , nsaid has limitation in prescribing because of gastrointestinal ( gi ) toxicity .
recently , nsaid - induced enteropathy has gained much at... | non - steroidal anti - inflammatory drugs ( nsaids ) are one of the most commonly prescribed drugs in the world .
nsaid - induced lower gastrointestinal ( gi ) complications are increasing while upper gi complications are decreasing .
lower gi events accounted for 40% of all serious gi events in patients on nsaids ... |
a consensus has been sought from the data analyses in order to establish a standard for nutritional support in cancer . however , the term " nutritional support " has been applied almost exclusively for the use of total parenteral nutrition , instead of the entire modalities of nutrition intervention , including nutrit... | the indications of nutrition support in cancer patients have been subject to controversy .
most studies address the effects of the method in increasing the survival or the tumor response rate .
few studies have focused on the effects in improving quality of life.after a brief review , we described the results of a ... |
conceptual methods for the correlation
of binding affinities with
drug structure ( 3d - qsars ) are vital to the drug development process .
the approaches include receptor - based methods , e.g. , free energy perturbation , the
linear response method , and the mining minima approach , and ligand - based methods... | we present the cellular quantitative structure
activity
relationship ( cell - qsar ) concept that adapts ligand - based and receptor - based
3d - qsar methods for use with cell - level activities .
the unknown intracellular
drug disposition is accounted for by the disposition function ( df ) ,
a model - bas... |
ad is a progressive and invariably fatal neurodegenerative disease
and the leading cause of senile dementia .
metabolic imbalance in diseased
neurons may contribute to neuropsychiatric symptoms that include
delusions and hallucinations , anxiety , mood disorder , and sleep
disturbance that are common in ad . ... | mechanisms that cause alzheimer 's disease ( ad ) , an invariably
fatal neurodegenerative disease , are unknown .
important recent
data indicate that neuronal heme deficiency may
contribute to ad pathogenesis .
if true , factors that contribute to
the intracellular heme deficiency could potentially alter th... |
a 3-year - old , female , spayed , domestic shorthair cat presented for dysuria and haematuria , unresponsive to antibiotic treatment . a small , fleshy
ultrasound identified a vaginal mass effect with mixed echogenicity measuring in excess of 3 cm .
vaginoscopy confirmed an extensive , fleshy , irregular mass that... | case summarya 3-year - old , female , spayed , domestic shorthair cat presented for dysuria and haematuria , unresponsive to antibiotic treatment .
a small , fleshy , erythematous mass protruded from the vaginal vault .
ultrasound identified a vaginal mass effect with mixed echogenicity measuring in excess of 3 cm ... |
we report a case of left adrenal schwannoma in a 62-year - old man , incidentally discovered on an abdominal computed tomography .
on admission , no remarkable findings were recognized in the patient 's blood and urine examination , including adrenal function .
macroscopically , the tumor ( 45 mm 30 mm , 60 g ) ar... | objective : we report a case of left adrenal schwannoma in a 62-year - old man , incidentally discovered on an abdominal computed tomography . it was successfully treated with laparoscopic adrenalectomy.methods:on admission , no remarkable findings were recognized in the patient 's blood and urine examination , includi... |
odontogenic tumors of epithelial origin commonly seen in the posterior mandible are often treated with surgical excision .
cantor and curtis provided a hemimandibulectomy classification for edentulous patient that can also be applied in partially edentulous arches .
apart from the deviation of mandible to resected ... | loss of mandibular continuity results in deviation of remaining mandibular segment toward the resected side primarily because of the loss of tissue involved in the surgical resection .
the success in rehabilitating a patient with hemimandibulectomy depends upon the nature and extent of the surgical defect , treatment... |
the assessment of patient recovery , rehabilitation , and clinical outcome postoperatively is important for the validation of the safety , efficacy , and economic dynamics of various spine surgical techniques.1 traditionally , patient - based subjective ratings of symptoms and function have been used to gauge the succe... | study design
prospective observational study.objective
patient - based subjective ratings of symptoms and function have traditionally been used to gauge the success and extent of recovery following spine surgery .
the main drawback of this type of assessment is the inherent subjectivity involved in patient scorin... |
a 36-year - old man with an itching and tingling sensation in the left l2 dermatome area for 3 months was referred to our clinic for pain management .
the patient did not have significant past medical history , and before coming to the clinic , he had been treated with gabapentin 600 mg 3 times a day by a dermatologi... | zoster sine herpete ( zsh ) is difficult to diagnosis during an acute period due to the absence of the characteristic zosteriform dermatomal rash ; therefore , progression to postherpetic neuralgia is more common than typical zoster .
in addition , misdiagnosis of other neuropathic pain as zsh is common in clinical s... |
thyroid cancer is the most prevalent endocrine malignancy ( accounting for > 92% endocrine malignancy ) , which can be classified histologically into follicular epithelial cell - derived papillary thyroid cancer ( ptc ) , follicular thyroid cancer ( ftc ) , anaplastic thyroid cancer ( atc ) , and parafollicular c - cel... | micrornas ( mirnas ) dysregulation has been shown to play a critical regulatory role in papillary thyroid carcinomas ( ptcs ) .
braf mutation is associated with poor clinicopathological outcomes in ptc . in order to identify a possible association between dysregulated mirna expression and braf mutation as well as cli... |
why is egypt 's hepatitis c ( hcv ) epidemic so much more intense than elsewhere ? numerous lines of evidence point to the key role that the widespread use of parenteral antischistosomal therapy ( pat ) played in this regard [ 1 , 2 ] .
however , question marks remain : numerous other countries have experienced simil... | a recent analysis of egypt 's first nationally representative survey of hepatitis c virus ( hcv ) infection found female genital cutting ( fgc ) to be an independent risk factor for hcv infection for women in urban areas .
we use the same dataset to extend this analysis . in an ecological analysis
, we find a stron... |
genome sequencing deciphered the number of protein - coding genes , establishing an initial estimation of complexity associated with human molecular biology .
two recent articles described creation of a draft of the human proteome [ 2 , 3 ] . nevertheless , considerable efforts are still required for exploring the ... | this work discusses bioinformatics and experimental approaches to explore the human proteome , a constellation of proteins expressed in different tissues and organs .
as the human proteome is not a static entity , it seems necessary to estimate the number of different protein species ( proteoforms ) and measure the n... |
the packaging of eukaryotic genomes into chromatin has fundamental effects on gene expression but how this is brought about still remains poorly understood .
histone proteins are highly conserved and are subject to many different posttranslational modifications ( ptms ) including acetylation and methylation ( rando a... | summarygene transcription responds to stress and metabolic signals to optimize growth and survival .
histone h3 ( h3 ) lysine 4 trimethylation ( k4me3 ) facilitates state changes , but how levels are coordinated with the environment is unclear . here
, we show that isomerization of h3 at the alanine 15-proline 16 (... |
the hormonal regulation of pheromone biosynthesis in moths was first demonstrated in the heliothine helicoverpa zea ( raina et al . , 1987 ) and a peptide isolated shortly thereafter ( raina et al . , 1989 ) .
pheromone biosynthesis activating neuropeptide ( pban ) was identified as a 33 amino acid c - terminal amida... | both males and females of heliothine moths utilize sex - pheromones during the mating process . females produce and release a sex pheromone for the long range attraction of males for mating .
production of sex pheromone in females is controlled by the peptide hormone ( pheromone biosynthesis activating neuropeptide ... |
the spleen is the greatest single mass of lymphatic tissue that lies between the left kidney , stomach and diaphragm ( 1 ) .
it has three surfaces : diaphragmatic , gastric and renal surface and the two borders : superior and inferior ( 1 ) .
this surface meets gastric and diaphragmatic surfaces respectively on the... | aim : an accessory spleen is an additional tissue of the spleen that may be found near the spleen . it is a congenital anomaly of the spleen that its incidence has been reported 10 - 30% of the population .
hence , the objective of this study was evaluation the incidence of accessory spleen in iranian cadavers.method... |
chronic nasal airway obstruction is one of the most frequent complaints visited to otolaryngologists by the patients .
deviation of nasal septum is a common anatomic variation and the most frequently causes of nasal obstruction ( 1 , 2 , 3 ) .
the nasal obstruction symptom evaluation scale ( nose ) has valid , reli... | introduction : surgical and medical treatments of nasal obstruction are a common parts of otolaryngologist practice .
the definitive treatment of deviated nasal septum is septoplasty.aim:in this study was to evaluate the values of subjective parameters , and active anterior rhinomanometry parameters prior and three m... |
beta - lactamase production is a common mechanism of resistance , particularly among gram - negative organisms.1 carbapenemases are distinct among the beta - lactams ; in addition to being able to hydrolyze most penicillins and cephalosporins , they are also able to hydrolyze the carbapenems .
there are two biochemic... | since the first new delhi metallo - beta - lactamase ( ndm ) report in 2009 , ndm has spread globally causing various types of infections .
ndm - positive organisms produce in vitro resistance phenotypes to carbapenems and many other antimicrobials .
it is thus surprising that the literature examining clinical expe... |
a 28-year - old pregnant primigravida in her 36th week of gestation was admitted to the labor suite in an early stage of active labor .
the patient was diagnosed with kss at the age of 23 years , which was confirmed by skeletal muscle biopsy .
her medical history included pigmentary retinopathy , diabetes mellitus ... | kearns - sayre syndrome ( kss ) is a rare mitochondrial myopathy that usually develops before 20 years of age .
it demonstrates multisystemic involvement with a triad of cardinal features : progressive ophthalmoplegia , pigmentary retinopathy , and cardiac conduction abnormalities .
in addition , patients might hav... |
teiser relies on calculating mutual information values between whole - genome measurements and millions of predefined structural motifs .
the decoy / scrambled experiments and sirna knock - downs were performed using lipofectamin 2000 reagent ( invitrogen ) . for hybridizations , we used human 444k whole - genome hum... | decoding post - transcriptional regulatory programs in rna is a critical step in the larger goal to develop predictive dynamical models of cellular behavior . despite recent efforts13 , the vast landscape of rna regulatory elements
remain largely uncharacterized .
a longstanding obstacle is the contribution of loca... |
fungal isolate
bvk - sma-2 was obtained from a soil sample collected
in buffalo valley , oklahoma .
a blast analysis of its its sequence
data demonstrated that the isolate was 99% identical to b.
ochroleuca .
for the purpose of comparing its growth and metabolite
profiles using two solid - phase culturing... | one of the challenges presented by candida infections
is that many of the isolates encountered in the clinic produce biofilms ,
which can decrease these pathogens susceptibilities to standard - of - care
antibiotic therapies .
inhibitors of fungal biofilm formation offer
a potential solution to counteracting ... |
benign deep thoracic wall cyst is uncommon ; however , operative management using an endoscopic approach should be reserved primarily for symptomatic cases with multiple comorbidities , where multiple attempts at aspiration have failed because it is associated with less postoperative pain , lower morbidity and faster r... | we present a 62-year - old male with a recurrent cyst in the left posterior chest .
mri demonstrated a fluid - filled cavity measuring 23 cm in length and 11 cm in width .
the cyst was aspirated demonstrating clear serous fluid . however , the cyst returned and he was referred to us for further treatment .
the cy... |
the health and economic burden of this disease is very large and with an increasing trend .
it is estimated that in the western countries , the prevalence of dm would increase 40 - 45% ( 1 ) .
diabetes mellitus type 2 is an established risk factor for development of coronary artery disease ( cad ) especially in wom... | backgroundprevalence of diabetes mellitus type 2 ( dm ) is increasing globally . considering the potential role of poly - unsaturated fatty acids in prevention of dm type 2 and lipid profiles improvement ,
some studies have been carried out on walnut . however , there are no studies on control of blood sugar in dm ty... |
ischemic stroke has many causes , clinical presentations , risk factors , courses , and outcomes . management and prognosis of patients with ischemic stroke is directly related to specific mechanisms of the ischemic stroke . in the acute phase of stroke , the most important predictors of outcome are stroke severity [ 2... | background . there is scant population - based information regarding predictors of stroke severity and long - term mortality for first - ever ischemic strokes .
the aims of this study were to determine the characteristics of patients who initially presented with first - ever ischemic stroke and to identify predictors... |
with rapid and ongoing developments in sample preparation , instrumentation and computational analysis , mass spectrometry - based quantitative proteomics is increasingly emerging as an approach of choice for addressing many aspects of biology .
one of the most popular formats of relative quantitative proteomics,(4 )... | quantitative mass spectrometry - based proteomics is a vital tool in modern life science research .
in contrast to the popularity of approaches for relative protein quantitation , the widespread use of absolute quantitation has been hampered by inefficient and expensive production of labeled protein standards .
to ... |
kikuchi - fujimoto disease ( kfd ) is a benign , self - limited , inflammatory disorder , first reported in japan .
this condition is more prevalent among women and typically occurs in the third decade of life .
it normally manifests as persistent , isolated cervical adenopathy with a recurrence rate of 3% .
the ... | introduction : kikuchi - fujimoto disease ( kfd ) is a benign , self - limited , inflammatory disorder , first reported in japan .
this condition is more prevalent among women and typically occurs in the third decade of life .
it normally manifests as persistent , isolated cervical adenopathy with a recurrence rate... |
the th1/th2 cell dichotomy and the essential role of the cytokine environment in driving their differentiation are well accepted .
interleukin ( il)-12 , acting via the transcription factors stat4 and t - bet , drives the differentiation of naive cd4 t cells into interferon ( ifn)- producing th1 cells , whereas il-4 ... | in the dark ages of t cell biology , we considered two fates for differentiated cd4 + t cells : t helper ( th)1 and th2 cells .
now we know that the reality is much more complex and interesting .
the newest th cell subset produces the cytokine il-17 .
new evidence shows that the il-17related cytokine il-25 is ess... |
a 61-year - old man came to the hospital complaining of bilateral flank pain . left
flank pain began approximately a month earlier , followed by right flank pain 4 days later .
the patient also complained of dyspnea on exertion , urinary frequency , and foamy urine .
he was diagnosed with hypertension 15 years pr... | tubulointerstitial nephritis and uveitis ( tinu ) syndrome is a rare disease entity usually occurring in children . in the present study
a case of tinu syndrome in an elderly patient is described and relevant literature is reviewed . a 61-year - old man presented with bilateral flank pain , urinary frequency , and fo... |
organochloride insecticides are chlorinated cyclic hydrocarbons with molecular weights in the range of 300 - 550 da .
they have a long half - life in the human body , and cause moderate toxicity .
one of such insecticides is endosulfan ( 6,7,8,9,10 - 10 hexachloro 1,5,5a,,6,9,9a - hexahydro-6-methano-2,4,3-hexadith... | organochloride insecticides are chlorinated cyclic hydrocarbons .
one of such insecticides is endosulfan ( 6,7,8,9,10 - 10 hexachloro 1,5,5a,6,9,9a - hexahydro-6-methano-2,4,3-hexadithioxanthiep in 3-oxide ) and it has been widely used in agriculture since 1960 .
the uncontrolled use of these compounds in developin... |
treatment of differentiated thyroid cancer ( dtc ) is usually a dual step procedure which consists of thyroidectomy and radioactive iodine treatment .
the other purposes are evaluating the disease regression by measuring the level of serum thyroglobulin and imaging of physiologic and pathologic radioiodine uptakes wi... | background : radioiodine therapy is used for the treatment of patients with differentiated thyroid cancer ( dtc ) who undergo total thyroidectomy .
after radioiodine administration , regulations require to quarantine these patients until their retained activity reduces to <33 mci .
some of the injected radioiodine ... |
the nature of one- and two - photon stimulated transition processes in organic molecules is a subject of both scientific and technological interest due to a number of nonlinear optical properties , such as two - photon induced fluorescence ( 2pf ) , nonlinear transmittance , two - photon absorption ( 2pa ) processes , ... | one- and two - photon stimulated emission transitions were investigated by the fluorescence quenching of a sulfonyl - containing fluorene compound , 2,7-bis(4-(phenylsulfonyl)styryl)-9,9-didecyl-9h - fluorene ( 1 ) , in solution at room temperature using a picosecond pumpprobe technique .
the nature of stimulated tra... |
internal hernia is defined as a fossa or defect of unusual size within a body cavity , into which intestines may intrude and become incarcerated or strangulated .
the origins of internal hernias are multiple and include congenital defects , inflammation , infectious processes , trauma , and postoperative defects . ba... | paraduodenal hernia , a rare congenital anomaly which arises from an error of rotation of the midgut , is the most common type of intraabdominal hernia .
there are two variants , right and left paraduodenal hernia , the right being less common .
we report the case of a 41-year - old patient with a right paraduodena... |
this descriptive cross - sectional study was conducted at a large 1200-bedded tertiary care hospital at pune .
a total of 50 consecutive adult hiv seropositive individuals were included in the study after obtaining informed consent .
the minimum age was 24 years , and the maximum age recorded was 73 years hiv serop... | background : reactions of people to a diagnosis of hiv and its effect on well - being vary greatly .
there is paucity of indian studies in this area.aim:to assess the level of anxiety , depression and quality of life in hiv seropositive individuals.materials and methods : it was a descriptive cross - sectional study ... |
approximately , 12% of children and adolescents in china are overweight according to the latest report .
the prevalence of overweight is even higher in big cities ; for example , in shanghai , 49.1% of boys and 30.8% of girls were reported to be overweight . in parallel with the prevalence of obesity , nonalcoholic f... | aim . we evaluated both direct and indirect hepatic fibrosis markers in obese children and their relationship with intrahepatic fat ( ihf ) content .
we also aimed to investigate the possible roles of ihf and fibrosis markers in metabolic syndrome ( ms ) .
methods .
189 obese children were divided into simple obe... |
we analyzed passive surveillance data on hca cases reported to the national center for disease control and public health ( tbilisi , georgia ) during 20102012 .
self - reported source of infection was ascertained from categorical responses that included butchering / slaughtering cattle , handling / preparing meat , p... | we assessed the occurrence of human cutaneous anthrax in georgia during 2010-2012 by examining demographic and spatial characteristics of reported cases .
reporting increased substantially , as did clustering of cases near urban centers .
control efforts , including education about anthrax and livestock vaccination... |
multiple sclerosis ( ms ) is a chronic disease that is associated with demyelination of
neurons and affects the myelin sheath of neurons in the central nervous system.the cause of this disease is still unknown , but
it seems that activation of immune mechanisms against myelin antigen is involved in this
regard . ... | introduction : the chronic nature of multiple sclerosis ( ms ) ,
have can leave devastating effects on quality of life and fatigue . the present research
aimed to study the effect of group mindfulness - based stress reduction ( mbsr ) and conscious
yoga program on the quality of life and fatigue severity among pa... |
for this study a priority intervention is one that has been shown , based on the best scientific data available , to deliver large population health benefits at a relatively low cost .
population - wide interventions , many of which are based on the implementation of healthy public policies , legislation and regulat... | introductionaction is urgently needed to curb the rising rates of non - communicable diseases ( ncds ) in low- and middle - income countries ( lmics ) and reduce the resulting social and economic burdens .
there is global evidence about the most cost - effective interventions for addressing the main ncd risk factors ... |
recent advances in stem cell research have brought the possibility of using somatic stem cells for organ regeneration one step closer to realization .
newly developed organs can then be used in clinical organ replacement . however , anatomically complicated organs such as the kidney have proven more refractory to ste... | significant advances have been made in stem cell research over the past decade . a number of nonhematopoietic sources of stem cells ( or progenitor cells )
have been identified , including endothelial stem cells and neural stem cells .
these discoveries have been a major step toward the use of stem cells for potent... |
a significant cause of medical error in health care is poor communication [ 1 , 2 ] . for the past three years
, miscommunication has been identified as one of the most frequently identified root causes of sentinel events reported to the joint commission , with 82% of the sentinel events in 2010 identifying communica... | failure to communicate openly and accurately to members of the healthcare team can result in medical error .
the purpose of this study was to explore the impact of nursing characteristics and environmental values on communication in the acute care setting .
nurses ( n = 135 ) on four medical - surgical units in two... |
nucleotide sequences diverge over time due to the combined effects of point mutation and homologous recombination .
recombination events cause changes to regions of contiguous bases in single events and were generally assumed to be rare in bacteria . however , there is growing evidence that homologous recombination h... | due to divergence , genetic variation is generally believed to be high among distantly related strains , low among closely related ones and little or none within the same classified clonal groups .
several recent genome - wide studies , however , revealed that significant genetic variation resides in a considerable n... |
dens in dente is a developmental malformation incident due to the in folding of enamel and dentin or an accentuation of the lingual pit of an incisor before calcification sets in .
various causes of this condition have been proposed which include focal growth retardation ( kronfeld 1934 ) , infection ( fischer 1936 ... | dens invaginatus , also known as dens in dente , is a rare anomaly affecting human dentition . the condition results in invagination of an amelodental structure within the pulp .
this case report discusses the current management protocol of dens invaginatus using a minimally invasive and nonsurgical treatment option ... |
silicosis is a fibrotic disease of the lungs caused by the inhalation and deposition of
free crystalline silicon dioxide ( sio2 ) or silica in the lung tissue1 .
silica exposure has long been a well - known occupational hazard in sandblasting , tunnelling ,
mining , but also in a range of other professions .
al... | sandblasting is traditionally known as a high - risk profession for potential
development of lung silicosis .
reported is a case of a sandblaster with confirmed
accelerated silicosis , a condition rather rarely diagnosed in the czech republic .
initially , the patient presented with progressive dry cough and ex... |
an 18-year - old female patient presented with inability to open both eyes for 6 weeks .
she had a history of fever from malaria 2 months back for which she was treated with oral chloroquin phosphate 500 mg .
she developed erythematous papular eruptions on the trunk , mouth , and limbs along with pain , redness , a... | an 18-year - old woman was referred with late sequelae of chloroquine - induced steven johnson syndrome . at the time of presentation , the symblepharon was involving the upper lids to almost the whole of the cornea , and part of the lower bulbar conjunctiva with the lower lid bilaterally .
other ocular examinations... |
primary teeth injuries are common in young children due to their lack of muscle coordination in the early years of life.14 these injuries primarily affect anterior primary teeth ; as a result of the resilient bone surrounding the primary teeth , these injuries are usually luxations.2,57 for laterally luxated teeth with... | this case report describes the repositioning of a laterally luxated primary central incisor with occlusal interference , using a composite inclined plane .
the patient was a 4-year - old girl who applied to our clinic three days after the injury . because of the time delay between injury and presentation , it was not... |
equimolar amounts of each of the naturally occurring amino acids was used to a total of 10-fold molar excess .
cysteine was not included in this mix and arginine was used at 1.5 molar concentration to compensate for previously observed low incorporation of this amino acid ( 4 ) .
the randomness of the peptide... | recombinant hla - a2 , hla - b8 , or hla - b53 heavy chain produced in escherichia coli was combined with recombinant 2-microglobulin ( 2 m ) and a pool of randomly synthesised nonamer peptides .
this mixture was allowed to refold to form stable major histocompatability complex ( mhc ) class i complexes , which w... |
ige mediated anaphylactic reaction can result in clinical symptoms ranging from mild cutaneous effects ( grade i ) to cardiac arrest from profound hypotension and circulatory collapse ( grade 4 ) terr classification .
to date we are unable to predict the severity of these reactions from the ige levels alone or the al... | circulating angiotensin - ii protects the circulation against sudden falls in blood pressure and is generated by the enzymatic action of angiotensin converting enzyme ( ace ) on angiotensin - i .
the ace genes have 2 allelic forms ,
i and d. the d genotype has both highest angiotensin - ii generation and serum... |
mechanical systems are used in buildings to provide conditioned air , dissipate thermal loads , dilute contaminants , and maintain pressure differences .
the characteristics of these systems and their operations h implications for the exposures of workers to environmental tobacco smoke ( ets ) and for the control of ... | |
endoscopic submucosal dissection ( esd ) is a standard treatment for early gastric cancer ( egc ) that does not have any risk of lymph node or distant metastases .
the indication for esd is determined by the lesion size , shape , ulceration , depth of invasion , and histologic differentiation . here
, we report a c... | endoscopic submucosal dissection ( esd ) is a standard treatment for early gastric cancer ( egc ) that does not have any risk of lymph node or distant metastases . here
, we report a case of egc resembling a diverticulum .
diverticular formation makes it difficult for endoscopists to determine the depth of invasion... |
more than 95% of thyroid cancers originate from thyroid follicular epithelial cells . among the well - differentiated forms , papillary thyroid carcinoma ( ptc ) is the most prevalent one , accounting for 7580% of cases , followed by the follicular thyroid carcinoma ( ftc ) , which represents approximately 1015% of all... | rac1b is a hyperactive variant of the small gtpase rac1 known to be a relevant molecular player in different cancers .
previous studies from our group lead to the evidence that its overexpression in papillary thyroid carcinoma ( ptc ) is associated with an unfavorable prognosis . in the present study
, we intended ... |
jarid2 ( jumonji , at - rich interactive domain 2 ) is the founding member of the jumonji family of proteins that can demethylate histones , although jarid2 itself is unable to do so ( klose et al . , 2006 ; landeira and fisher , 2011 ) .
jarid2 was discovered in 1995 as a regulator of neural development in a gene t... | summaryjarid2 is part of the polycomb repressor complex 2 ( prc2 ) responsible for genome - wide h3k27me3 deposition . unlike other prc2-deficient embryonic stem cells ( escs ) , however , jarid2-deficient escs show a severe differentiation block , altered colony morphology , and distinctive patterns of deregulated gen... |
patients who underwent maxillectomy due to benign or malignant tumor , will have defect in palatal area .
because of this defect , patients will be more likely to have oro - nasal communication , change of facial profile , difficulty in speaking , mastication , and even deglutition . to overcome these problems , surg... | patients who underwent resection of maxilla due to benign or malignant tumor , or accident will have defect in palatal area .
they get retention , support and stability from remaining tissues which are hardly optimal .
the advantage of swing - lock attachment design is having multiple contacts on labial and lingual... |
polymyositis is a rare and gradually progressive autoimmune disease of skeletal muscle.1 two main types of renal involvement have been described : acute tubular necrosis related to rhabdomyolysis and glomerulonephritis.2 previous reports have demonstrated glomerular proteinuria in polymyositis ; however , overflow prot... | polymyositis is a rare and gradually progressive autoimmune disease of skeletal muscle .
two main types of renal involvement have been described : acute tubular necrosis related to rhabdomyolysis and glomerulonephritis .
however , cases of overflow proteinuria related to polymyositis have rarely been reported .
h... |
since iron deregulation is relevant for alzheimer 's disease ( ad ) , in this review we focus on the relevance of iron metabolism regulation , particularly in the central nervous system ( cns ) .
iron accumulation occurs in specific brain areas that are affected in ad patients , such as the hippocampus and the cortex... | iron is essential for mammalian cellular homeostasis .
however , in excess , it promotes free radical formation and is associated with aging - related progressive deterioration and with neurodegenerative disorders such as alzheimer 's disease ( ad ) .
there are no mechanisms to excrete iron , which makes iron homeo... |
giant cell tumors commonly occur around the knee joint in the age group of 20 - 30 years .
management of large bone defects after resection is a challenge and is of ten complicated with non - union of grafts , infection and delayed weight bearing .
a 37-year - old male presented with an aggressive recurrent giant c... | introduction : giant cell tumors commonly occur around the knee joint in the age group of 20 - 30 years .
they are treated with intra - lesional curettage or local resection and limb reconstruction .
management of large bone defects after resection is a challenge and is of ten complicated with non - union of grafts... |
the rapid growth of technological possibilities in health care is accompanied by a growing need to determine an emerging technology s desirability before it is introduced in the health care system . in the 1970s and 1980s health technology assessment ( hta ) was developed as a way to facilitate collective decision maki... | health technology assessment ( hta ) was developed in the 1970s and 1980s to facilitate decision making on the desirability of new biomedical technologies . since then , many of the standard tools and methods of hta have been criticized for their implicit normativity . at the same time research into the character of te... |
darwin referred to the rapid success of flowering plants in evolution as an ' abominable mystery ' .
a great deal of this success relies on the peculiar ways of sexual reproduction that they have evolved .
the facts that delight us and spark our curiosity about the sexual behavior of animals , in fact the essence o... | pollen tubes follow attractants secreted by the ovules . in a recent paper in bmc plant biology , stewman and
colleagues have quantified the parameters of this attraction and used them to calibrate a mathematical model that reproduces the process and enables predictions on the nature of the female attractant and the ... |
levamisole , an anthelmintic agent that targets the nicotinic acetylcholine receptors , is usually used as an immunostimulant in combination with 5-fluorouracil ( 5-fu ) to treat colorectal cancer since 1990 .
it has been shown that combination of these two drugs decrease the risk of clinical recurrence and to increa... | levamisole is an anthelmintic agent and also immunostimulant drug which is used to treat colorectal cancer . the present study aimed to show accidental consumption of levamisole alone induced multifocal inflammatory leukoencephalopathy .
a 53-year - old male was admitted to the neurology department of farabi hospital... |
most of our current knowledge about the central nervous system ( cns ) and neural function in patients with neurological diseases has been obtained from postmortem tissues that often represent the end stage of the disease .
the inability to sample live cns tissues impedes our progress to understand aspects of the neu... | remarkable advances in cellular reprogramming have made it possible to generate pluripotent stem cells from somatic cells , such as fibroblasts obtained from human skin biopsies . as a result , human diseases can now be investigated in relevant cell populations derived from induced pluripotent stem cells ( ipscs ) of p... |
demineralization or white spot lesion ( wsl ) development in the enamel in association with orthodontic treatment with fixed appliances remains a well - known clinical problem for dental specialists .
various methods how to prevent its formation are discussed in the literature , but still it is not determined which o... | abstractobjectivesthe aim of the systematic literature review is to update the evidence for the prevention of white spot lesions , using materials containing fluoride and/or casein phosphopeptide - amorphous calcium phosphate during and after treatment with fixed orthodontic appliances.material and methodsinformation s... |
prescribing psychotropic medication in pregnancy is a complex issue involving assessment of the risk of leaving an untreated psychiatric illness with its attendant complications versus the risk of adverse effects on the fetus .
olanzapine , one of the 2 generation antipsychotics , is a category c drug and there is no... | olanzapine , a 2nd generation antipsychotic , is in use in the clinical practice for nearly a decade and a half now .
it is classified as a category c drug with very few reports of its toxic effects on the fetus . in general , the risk benefit analysis warrants its use in pregnancy .
we report a case of microcephal... |
equilibrium simulation
of molecular systems entails sampling of
conformations from the appropriate distribution corresponding to a
thermodynamic ensemble , such as the boltzmann distribution for the
isothermal canonical ensemble .
given a potential energy function that
describes the interatomic interactions... | we
present two methods for barrierless equilibrium sampling of
molecular systems based on the recently proposed kirkwood method ( j. chem .
phys.2009 , 130 ,
134102 ) .
kirkwood sampling employs low - order correlations among internal
coordinates of a molecule for random ( or non - markovian ) sampling of
... |
it is now widely recognized
that many rna molecules are predisposed
to forming complexes with proteins by fluctuating spontaneously through
an ensemble of structural states .
protein
recognition is referred to as conformational capture .
a description of the physical principles involved in forming rna pr... | complex rna structures are constructed
from helical segments connected
by flexible loops that move spontaneously and in response to binding
of small molecule ligands and proteins .
understanding the conformational
variability of rna requires the characterization of the coupled time
evolution of interconnect... |
cellular genomes are constantly exposed to various sources of dna damage ( ciccia and elledge , 2010 , hanawalt , 2015 , hoeijmakers , 2009 , jackson and bartek , 2009 ) , threatening not only genome stability , but also the integrity of chromatin organization ( adam et al . , 2015 , lukas et al . , 2011 ,
the basi... | summarychromatin integrity is critical for cell function and identity but is challenged by dna damage . to understand how chromatin architecture and the information that it conveys are preserved or altered following genotoxic stress , we established a system for real - time tracking of parental histones , which charact... |
critical limb ischaemia ( cli ) needs straight line blood flow to the foot for adequate revascularization .
five - year follow up on cli revascularization with either an endovascular or open surgery
first approach showed that both methods had equivalent limb salvage rates and amputation - free survival in properly ... | retrograde puncture via patent pedal vessels can be attempted in failed antegrade approach for infrapopliteal long chronic total occlusion . however in cases where the pedal vessels are unable to be visualized via duplex ultrasonography or fluoroscopy an open approach offers an additional option to a vascular surgeon f... |
chronic myeloid leukemia ( cml ) is a myeloproliferative disorder of blood stem cells.1 the causative molecular defect is the bcr - abl protein , which is encoded by the philadelphia chromosome ( ph).2 this genetic anomaly arises from an exchange of genetic material between chromosomes 9 and 22 , which results in the f... | we report our experience in 4 patients with chronic myeloid leukemia ( cml ) who had discontinued imatinib as a result of adverse events and had switched to dasatinib . the chronic phase ( n 2 ) and accelerated phase ( n 2 ) cml patients received dasatinib at starting dose of 100 and 140 mg once daily , respectively . ... |
atopy is characterised by a tendency to mount immunoglobulin e ( ige)-mediated , type i hypersensitivity reactions to allergens .
10 - 20 percent of the population are affected by atopy and the prevalence of atopic diseases in children and adults has increased in these countries from the 1970s ( asher et al . , 2006 ... | backgroundevidence suggests that higher levels of vitamin d and calcium are associated with greater lung function and that vitamin d is inversely associated with atopic sensitisation .
it is unknown whether the associations of vitamin d and calcium with lung function are independent of each other or mediated by atopi... |
a total of 4 representative aquatic plants , eleocharis kuroguwai ohwi ( belonging to the order cyperales ) , hydrocharis dubia backer ( belonging to the order psammophytes ) , salvinia natans all .
( a pteridophyte belonging to the order polypodiales ) , and zizania latifolia turcz . ( a gramineous plant , belonging... | a total of 4 aquatic plants , eleocharis kuroguwai ohwi , hydrocharis dubia backer , salvinia natans all . , and zizania latifolia turcz . , were sampled from representative two wetlands of south korea .
a total of 38 endophytic fungal strains were isolated from aquatic plants native to the daepyeong wetland , and 27... |
pgp 9.5 is a ubiquitin - carboxyl hydrolase that is expressed in nerve tissues from mice brains at all stages of differentiation , and thus it has been regarded as an universal cytoplasmic marker for neuroendocrine cells and neuroendocrine tumors ( nets ) since the 1980s .
however , pgp 9.5 has not gained popularity ... | aims / hypothesis : protein gene product 9.5 ( pgp 9.5 ) is a marker for neuroendocrine cells but has not been used for pancreatic islet cells and pancreatic endocrine tumors ( pets ) .
antibodies for pgp 9.5 are now commercially available for immunocytochemical study , with which immunostaining may be able to differ... |
etomidate is a popular anesthetic agent since it is associated with hemodynamic stability , minimal respiratory depression , cerebral protection , and rapid recovery after either a single dose or a continuous infusion .
the mechanism of myoclonus is not clear and does not seem to be associated with seizure - like ele... | background and aims : myoclonus is a major side - effect following etomidate injection requiring use of medical intervention.material and methods : in this double - blinded clinical trial , 50 consecutive patients , randomly received sufentanil 0.2 g / kg or midazolam 0.015 mg / kg , 90 s before induction of anesthesia... |
metabolic syndrome refers to a cluster of known disorders that increase the risk for morbidity and mortality from cardiovascular disease ( cvd ) and type 2 diabetes [ 1 , 2 ] .
metabolic syndrome is defined as the occurrence of 3 of any of the 5 following factors : obesity , elevated triglyceride ( tg ) , low hdl - c... | background .
although there is a reported association between lifestyle factors and metabolic syndrome , very few studies have used national level data restricted to the african americans ( aas ) in the united states ( us ) .
methods .
a cross - sectional evaluation was conducted using the national health and nut... |
the incidence of tooth abnormalities in children with cleft lip and palate is higher than that in children without clefts3,5,16 .
tooth abnormalities reported in the literature are related to the number , size , shape and eruption of teeth3,8,16 .
disturbances involving anomalies in tooth eruption are called ectopi... | disturbances involving abnormalities in tooth eruption are named ectopia .
transmigration is the name assigned to ectopia in the presence of teeth in areas distant from the alveolar process .
initial angulation of the tooth bud of the second premolar and premature loss of permanent mandibular 1st molars can influen... |
c c bond activation / functionalization recently merged a useful method for synthesizing complex scaffolds from relatively simpler starting materials .
c bonds was first reported by liebeskind using a stoichiometric co - complex ( fig .
seminal work by murakami / ito described intramolecular insertions of styrene ... | bridged - ring systems are widely found in natural products and successful syntheses of them frequently feature intramolecular diels - alder ( imda ) reactions .
these reactions are subclassified as either type i or type ii imdas depending on how the diene motif is tethered to the rest of the substrate - type i are t... |
although dental caries significantly decreased in the western countries , it is still considered a major public health problem affecting , in the form of early childhood caries ( ecc ) , most of the preschool children in many countries world - wide .
the american academy of pediatric dentistry defined ecc as the pre... | aim : the aim of this survey was to evaluate the knowledge and awareness of parents and caregivers about potential oral health risk factors for their children in their first months of life ( 330 months).materials and methods : the participation to the survey was proposed to all parents or caregivers of children attendi... |
feigned illness with the goal of receiving medical treatment for its own sake is known as munchausen 's syndrome .
the syndrome is named after baron von munchausen ( 1720 - 1791 ) by asher in 1951 .
these patients have dramatic , but nonexistent symptoms and demand radical treatment . a similar entity of symptoms i... | this short communication is about munchausen 's syndrome in a group of pediatric patients and co morbid munchausen 's syndrome by proxy . a 7-year - old girl presented with spontaneous bleeding from forehead , eyes and scalp .
the girl was investigated thoroughly by pediatricians at a tertiary care hospital in wester... |
the harmony of the smile is determined not only by the shape , the position , and the colour of teeth but also by the gingival tissues
it is one of the several developmental or acquired deformities and conditions that manifest in the periodontium .
it is an aesthetic concern that can affect a large portion of the p... | excessive gingival display , commonly referred to as
gummy smile is a major hurdle in overall personality of an individual .
gummy smile , secondary to altered passive eruption and tooth mal - positioning , can be predictably treated with surgery and orthodontic therapy . in patients with jaw deformities , orthogna... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.