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primary sjgren 's syndrome ( pss ) , also known as autoimmune epithelitis , is a common chronic autoimmune disease characterised by the inflammation of exocrine glands and the clinical signs of xerostomia and keratoconjunctivitis sicca . a combination of environmental , genetic , and possibly hormonal factors leads t...
recently , we revealed the importance of follicular helper t cells ( tfh ) in the pathogenesis of primary sjgren 's syndrome ( pss ) . in the present study , we focused on the site of the inflammation and determined the composition of lymphocyte infiltration in labial salivary gland ( lsg ) biopsies with special emphas...
peptide mass spectrometry provides a powerful method to analyze proteome expression in cell lysates . at the core of this method , experimental mass spectra of fragmented peptides the accuracy of peptide matching depends critically on the effectiveness of algorithms that match the theoretical and experiment...
peptide mass spectrometry relies crucially on algorithms that match peptides to spectra . we describe a method to evaluate the accuracy of these algorithms based on the masses of parent proteins before trypsin endoprotease digestion . measurement of conformance to parent proteins provides a score for comp...
lupus nephritis ( ln ) is one of the most frequent manifestations of systemic lupus erythematosus ( sle ) and represents a major determinant of disease morbidity and mortality . its clinical course is often characterized by flares of activity alternated with periods of quiescence , generally induced by therapy . th...
few studies have correlated serum biomarkers with renal histology , the gold standard for renal activity , in lupus nephritis ( ln ) . we tested a panel of autoantibodies and complement at the time of kidney biopsy and after treatment . anti - dsdna , anti - nucleosome , anti - ribosome p , and anti - c1q antibodie...
giardiasis causes significant worldwide morbidity with an estimated 184 million symptomatic cases annually ( pires et al . , 2015 ) and an associated 171,100 disability - adjusted life years ( dalys ) ( kirk et al . , 2015 while giardiasis is more prevalent in the developing world it is also a burden in developed c...
giardia duodenalis is an intestinal parasite that causes giardiasis , a widespread human gastrointestinal disease . treatment of giardiasis relies on a small arsenal of compounds that can suffer from limitations including side - effects , variable treatment efficacy and parasite drug resistance . thus new anti - gi...
the prognostic potential of different laboratory tests was evaluated in 15 naturally infected animals , of which 12 dogs were presented to the clinic for small animal internal medicine at the vetsuisse faculty , university of zurich , and 3 dogs to private veterinary practices in switzerland in the years 2011 to 2013 ....
backgroundcanine babesiosis , caused by babesia canis , is a prevalent and clinically relevant disease in europe . severe acute babesiosis is characterized by a high mortality but prognosis is not always correlated with clinical signs nor with the level of parasitemia.objectivethis study evaluated prognostic markers ...
it is usually due to congenital dysplasia , trauma , strain , or other causes of abnormalities in the bony connection between adjacent vertebrae , leading to partial or complete slippage of one vertebrae on adjacent vertebrae . the typical symptoms of this condition are neurological deficits , including low back pain...
abstractradiographic features of consecutive lumbar spondylolisthesis were retrospectively analyzed in a total of 17 patients treated for this condition at the third hospital of hebei medical university from june 2005 to march 2012.to investigate the radiographic features , pelvic compensatory mechanisms , and possible...
sample size was calculated to measure a difference of greater than 2 mm of hg between the two instruments with an estimated standard deviation of 4 mm , for 80% power and a type 1 error of 5% . we needed 34 patients to measure this difference and recruited 40 consecutive adult subjects attending a glaucoma ...
the aim of the study was to assess agreement between two commercially available applanation tonometers for the measurement of intraocular pressure ( iop ) . forty subjects underwent iop measurement on two accurately calibrated goldmann type applanation tonometers ( zeiss at 030 ( gatz ) and inami l-5110(gat...
decentration can lead to undesired complications such as decreased visual acuity , astigmatism , glare , and monocular diplopia , which would overcome the purposes of the surgery ( 1 , 2 ) . to minimize the risk of decentration measurement of the angle kappa between the visual and papillary axes plays an important ro...
background : the angle kappa is important in proper centration of corneal ablation in keratorefractive surgery . orbscan ii device is widely used preoperatively in photoablation surgeries and can be used to measure the angle kappa.objectives:this study aimed to determine the mean angle kappa and its intercepts in hea...
in 1951 , eldon j. gardner ( 1909 1989 ) , a college teacher of genetics , first described the syndrome , as a rare autosomal , dominant , inherited disorder with a high degree of penetrance , characterized by a triad of multiple osteomas , colonic polyposis , and mesenchymal tumors of the skin and soft tissues . it...
gardner 's syndrome is an autosomal dominant disease and is a subtype of familial adenomatous polyposis . it is characterized by adenomatous intestinal polyps , multiple osteomas in the skull , maxillae , mandible , and multiple cutaneous and subcutaneous masses ( epidermoids and desmoid ) . intestinal polyps , if ...
tuberculosis ( tb ) is one of the most common infections worldwide , and in 2012 , an estimated 8.6 million people developed tb and 1.3 million died from the disease ( including 320,000 deaths among hiv - positive people ) [ 1 , 2 ] . mycobacterium tuberculosis ( mtb ) is an intracellular pathogen capable of infectin...
tuberculosis ( tb ) is considered a major worldwide health problem with 10 million new cases diagnosed each year . our understanding of tb immunology has become greater and more refined since the identification of mycobacterium tuberculosis ( mtb ) as an etiologic agent and the recognition of new signaling pathways m...
a 44-year - old , para 2 , female with chronic pelvic pain was admitted for microlaparoscopic conscious pain mapping to evaluate the cause of her pain . the patient had undergone a cesarean hysterectomy in 1979 during her last delivery secondary to having multiple large leiomyomata . over the next decade , she suff...
chronic pelvic pain is a debilitating , life - altering syndrome that negatively affects a woman 's quality of life and personal relationships . many women continue to suffer with pelvic pain despite having undergone multiple medical and surgical treatments . unfortunately , some women are incorrectly labeled as havi...
the classical or canonical model of signaling by cytokines such as the interferons ( ifns ) involves ligand interaction with receptor extracellular domain , followed by allosteric changes in the receptor cytoplasmic domain that results in autophosphorylation of the relevant janus tyrosine kinases ( jaks ) and subsequ...
the canonical model of cytokine signaling via the jak / stat pathway dominates our view of signal transduction but provides no insight into the significance of the simultaneous presence of activated jaks and stats in the nucleus of cells treated with cytokines . such a mechanistic shortcoming challenges the usefulness ...
due to industrialization and urbanization , the standard of living continues to rise particularly in developing countries . this has led to weight gain and obesity , which are posing a threat to the health of citizens . obesity is perhaps the most prevalent form of malnutrition in developing countries , both among ...
background : the blood pressure and anthropometric measurements are important for evaluating the health of children , adolescents as well as adults.aim:the aim is to study the blood pressure and body dimensions and to find out the prevalence of overweight / obesity and hypertension among adults.materials and methods : ...
a 74-year - old man with infective endocarditis and valvular vegetations was scheduled to undergo aortic and mitral valvular replacement surgery . he had a previous medical history of laparoscopic radical prostatectomy with pelvic lymph node dissection for prostatic cancer , and had received hormonal and radiation th...
transesophageal echocardiography ( tee ) is a relatively noninvasive and highly valuable diagnostic modality to monitor cardiac surgery . tee is utilized to estimate the results of the surgical correction or the cardiac function on a real time basis . accordingly , the frequency of tee usage is increasing . previ...
since standard preclinical models have notoriously overestimated the clinical potential of her tkis , we challenged the traditional approach to evaluating tkis in these models . traditionally , signaling inhibitors are thought to have a continuous suppressive effect through rapid and sustained inhibition of their dir...
oncogenic tyrosine kinases have proven to be promising targets for the development of highly effective anticancer drugs . however her family tyrosine kinase inhibitors ( tkis ) show only limited activity against her2-driven cancers despite effective inhibition of egfr and her2 in vivo 18 . the reasons for this ar...
substance abuse poses a major political , social and health challenge worldwide . besides being a personal risk , addiction is a social problem and imposes harmful and permanent effects on society . at present , 3.6%6.9% of adults ( 1564-years - old individuals ) are under the influence of illicit substances . accord...
introduction and aim . substance abuse imposes hazards on human health in all biopsychosocial aspects . limited studies exist on epidemiology of substance abuse and its trend in rural areas . the present study aimed to compare substance abuse in one of the rural areas of southeast iran , in a 12-year period ( 200...
periodontitis is a common local inflammatory disease of tooth - supporting tissues initiated by microorganisms present in the dental plaque . as the disease progresses , there is periodontal pocket formation with increased attachment loss , alveolar bone destruction , and increased tooth mobility that ultimately resu...
aim : the study aimed to assess the levels of awareness about the mutual relationship between diabetes and periodontitis among high - risk age group of the general population and to assess the attitude of general physicians in suggesting diabetic patients to visit a dentist.materials and methods : a structured , closed...
the risk of occupational exposure to blood borne pathogens ( including hepatitis b , hepatitis c and hiv ) via sharp injuries such as needle stick injuries ( nsis ) among health care workers , especially dental , nursing and midwifery students , is a challenging issue , , , , , . inadequate staff , lack of experience...
background : the risk of occupational exposure to blood borne pathogens ( including hepatitis b , hepatitis c and hiv ) via sharp injuries such as needle stick injuries ( nsis ) among health care workers , especially dental , nursing and midwifery students is a challenging issue . inadequate staff , lack of experienc...
breast milk provides an abundance of nutrients in bioavailable forms that are crucial for the infant 's normal growth and development . exclusive breastfeeding provides strong protection against lower respiratory tract infections , gastroenteritis , middle ear infections , and childhood obesity [ 25 ] . currently o...
the type of gift bags given to new mothers at the time of discharge from the hospital can influence their confidence in breastfeeding . most hospitals in the us continue to distribute commercial gift bags containing formula samples despite the reported negative influence of commercial bags on the duration of breastfe...
the inrhythm study is a prospective study of af and its relationship to psychosocial and ci . participants with symptomatic af were recruited and followed at 1 of 3 ambulatory clinics associated with the university of massachusetts medical center af treatment clinic ( heywood hospital , marlborough hospital , and the...
background : impairments in psychosocial status and cognition relate to poor clinical outcomes in patients with atrial fibrillation ( af ) . however , how often these conditions co - occur and associations between burden of psychosocial and cognitive impairment and quality of life ( qol ) have not been systematically...
subscapularis tendon is one of the four rotator cuff tendons which in addition include supraspinatus , infraspinatus , and teres minor . subscapularis inserts onto the lesser tuberosity of the humerus , whereas the other rotator cuff tendons insert into the greater tuberosity.1 in 1834 , smith was credited as describ...
background : rotator cuff tears are a common cause of shoulder pain and dysfunction . more recently , there has been a renewed interest in understanding the subscapularis tears . there are multiple articles in the literature showing the short term results of isolated subscapularis tendon repair . however , the midt...
however spinal tumors constitute only 1 - 10% of all pediatric central nervous system tumors . they are firm encapsulated benign tumors and total surgical removal can be achieved in most of the cases with an excellent outcome . the study included 21 patients in the pediatric age group ( < 18 years ) of spinal schwa...
objective : the objective was to analyze the demography , clinical presentation , and management of spinal intradural schwannomas in pediatric population.materials and methods : this retrospective study includes 21 pediatric patients ( under 18 years of age ) who underwent surgery for spinal intradural schwannomas from...
an agilent 1200 series hplc system equipped with a diode array detector and a phenomenex c18 column ( 5 m , 250 21.2 mm ) was used for preparative hplc . for hplc - ms analysis , an agilent hplc system equipped with a diode array detector and a 6130 series quadrupole mass spectrometer was used with a pheno...
three new members of the angucycline class of antibiotics , pseudonocardones a c ( 13 ) , along with the known antibiotics 6-deoxy-8-o - methylrabelomycin ( 4 ) and x-14881 e ( 5 ) have been isolated from the culture of a pseudonocardia strain associated with the fungus - growing ant apterostigma dentigerum ...
the novel h1n1 influenza outbreak in april 2009 was unprecedented in several respects including the new virus , the season of origin ( spring , not late fall ) , and the cohort at risk for infection and death ( children and young adults , not infants and the elderly ) [ 14 ] . the pandemic h1n1 2009 virus is currentl...
summarybackgroundthe university environment poses a high risk of spreading infectious diseases , particularly the 2009 pandemic influenza h1n1 , as it is a mass gathering place for youth . this study aimed to evaluate the predictors of stress symptoms among chinese university students during the 2009 h1n1 influenza p...
polymyalgia rheumatica ( pmr ) is a clinical syndrome characterized by muscle pain and stiffness in the neck , shoulders and pelvic girdle . it is often associated with giant cell arteritis ( gca ) , suggesting that these diseases represent different clinical manifestations of the same disease process . only a few ...
a 70-year - old man complained of muscle pain in his neck , shoulders and pelvic girdle . proteinuria and hematuria subsequently developed . blood analysis showed increased acute phase reactants . the histology of renal biopsy showed diffuse endocapillary proliferative glomerulonephritis . there were no signs o...
numerous proton magnetic resonance spectroscopy ( 1h - mrs ) studies have linked cytosolic choline levels to the neuropathology of mood disorders ( 17 ) . increases in choline in depressed subjects have been noted in adults ( 1,3 ) and in pediatric samples ( 4,5 ) . auer and others ( 8) did not note any significant...
purpose of study : the prefrontal cortex has been previously implicated in the neuropathology of major depressive disorder ( mdd ) . hence , we used proton magnetic resonance spectroscopy ( 1h - mrs ) to examine choline levels in the prefrontal cortex of youth with major depression . basic procedures : twelve age- ...
the apicomplexan parasite cryptosporidium parvum is a waterborne enteric protozoan with significant veterinary importance ( 1 ) . cryptosporidiosis in the immunocompetent host is a self - limiting diarrheal illness , but in immunosuppressed individuals such as those with human immunodeficiency virus ( hiv ) infection...
background : rhoptries are unique secretory / excretory organelles that are found exclusively in the apicomplexa , and their contents are discharged at the time of invasion and are critical in the establishment of productive infection . several rhoptry proteins have been identified in toxoplasma gondii , plasmodium f...
an ideally aligned posture is regarded as one in which there is perfect alignment of the weight - bearing segment , and it is commonly described by the vertical line of gravity passing anterior to the knee , posterior to the hip , through the bodies of vertebrae in both the cervical and lumbar spine , through the...
[ purpose ] the aim of the present study was to investigate correlation between head posture and proprioceptive function in the cervical region . [ subjects and methods ] seventy - two subjects ( 35 males and 37 females ) participated in this study . for measurement of head posture , the craniovertebral angle w...
we report a case of 18-year - old boy who presented with vomiting , backache , and fever for 1-month , diagnosed to have anaplastic large cell lymphoma of urinary bladder with hypercalcemia and metastatic calcification in multiple viscera . his computed tomography scan was suggestive of soft tissue lesion in the urin...
cardiovascular malformations ( cvm ) are one of the most prevalent groups of birth defects and include congenital heart defects and vessels anomalies . in the populations covered by the european surveillance of congenital anomalies ( eurocat ) , the total prevalence of cvm in 2000 - 2005 was 7.97 per 1000 births ( incl...
backgroundcardiovascular malformations ( cvm ) are one of the most prevalent groups of birth defects . knowledge about the prevalence , distribution and survival in russia has been limited . the aim of our study was to assess the perinatal prevalence , structure and risk factors for cvm among newborns in monchegors...
it is the most common dermatological disease , affecting approximately 80% of teenagers between 12 and 18 years of age . it is predominant in female adolescents , where it first appears around 14 years of age , and is less severe than in males who start showing symptoms at approximately 16 years of age.1 acne is the ...
backgroundacne is a chronic disease of the pilosebaceous unit that mainly affects adolescents . it is the most common dermatological problem , affecting approximately 80% of teenagers between 12 and 18 years of age . diagnosis is clinical and is based on the patient s age at the time the lesions first appear , and ...
ovarian hyperstimulation syndrome ( ohss ) is an iatrogenic complication of assisted reproductive technology ( art ) with development of multiple follicles . ohss is characterized by cystic enlargement of the ovaries and an acute fluid shift from the intravascular compartment to the third space , which may result in ...
background : the effect of ovarian hyperstimulation syndrome ( ohss ) on pregnancy outcomes of in vitro fertilization ( ivf ) patients is still ambiguous . this study aimed to analyze pregnancy outcomes of ivf with or without ohss in chinese patients.methods:a retrospective cohort study was undertaken to compare preg...
in recent time we are observing in the context of oncological breast surgery , an increasing trend towards the more effective treatment with minimum invasiveness , with the intent to combine the local control of the disease with the respect of patient s quality of life . the introduction of conservative breast surger...
after the results obtained in the two randomized clinical trial , the eliot trial and the targit - a trial , a heated debate is going on concerning the question of applying intraoperative radiotherapy ( iort ) instead of postoperative whole breast irradiation ( wbi ) after breast conservative treatment . currently , ...
the definition of ' elderly ' may vary according to chronological , biological , psychological , and social aspects , however , most developed countries have accepted the chronological age of 65 years as a definition of ' elderly ' or older person , as defined by the world health organization ( who ) . advances in me...
objectivethe aim of this study is to evaluate the clinical course of intracranial aneurysm in patients aged 65 years and older and the immediate outcome after its aggressive management.materials and methodswe performed a retrospective analysis using the medical records of 159 elderly patients managed at our institute f...
at present , it is accepted that natural killer ( nk ) cells are a subset of lymphocytes with an important role in the early response to tumors [ 1 , 2 ] . they destroy tumor cells by two main cytotoxic pathways : a perforin / granzyme - mediated secretory mechanism and a tnf - family ligand - mediated apoptotic kill...
objectives . the purpose of the present study is to verify if the degree of immunological response against metastatic tumors , measured by the number of cd57 + nk - cells in the tissue of a brain metastasis , influences the later development of new brain metastases or tumor recurrence . patients and methods . cd57 + nk...
an increased risk of als is associated with certain populations who have a history of extensive physical contact such as varsity athletics , professional soccer players , and military veterans [ 13 ] . motor nerve injury as a trigger to degeneration has been proposed in these populations , but the underlying mechanis...
an increased risk of als has been reported for veterans , varsity athletes , and professional football players . the mechanism underlying the increased risk in these populations has not been identified ; however , it has been proposed that motor nerve injury may trigger immune responses which , in turn , can accelera...
collapsing focal segmental glomerulosclerosis ( fsgs ) , also known as collapsing glomerulopathy ( cg ) , was first described in association with hiv infection . subsequently the clinical course of cg is characterized by rapid progression to end - stage renal disease and a dismal response to medical therapy . a sur...
collapsing focal segmental glomerulosclerosis ( fsgs ) , or collapsing glomerulopathy ( cg ) , responds poorly to commonly employed therapies , with a high proportion of patients progressing to end - stage renal disease . we report an adult in a nephrotic state , diagnosed with minimal - change disease on biopsy , wh...
body fat content is a well - established risk factor for the development of hypertension ( 1 , 2 ) , and recent studies have suggested that abdominal visceral fat has a stronger association with hypertension incidence than does total fat mass ( 35 ) . although bmi is significantly related to an individual s body fat co...
abstractbackgroundcurrently , obesity has become a worldwide health problem and yet little is known about the impact of changes in obesity indicator on incident hypertension . the aim of this study was to compare the impact of changes in the wc and bmi on incident hypertension in a cohort population.methodsafter a ba...
primary ovarian failure ( pof ) is a syndrome composed of amenorrhea , estrogen deficiency and follicular stimulating hormone ( fsh ) of menopausal ranges in young women . in this article a 29-year old woman with a history of primary amenorrhea attended hospital with full term pregnancy . she had experienced a few ...
introductionprimary ovarian failure ( pof ) is a syndrome composed of amenorrhea , estrogen deficiency and follicular stimulating hormone ( fsh ) of menopausal ranges in young women . in this article , we report a case of primary amenorrhea that presented with full term pregnancy.case presentationa 29-year old woman ...
since 1978 , when the first baby conceived in vitro was born , in vitro fertilization ( ivf ) has become a major method for treating infertility . although ivf procedures have been greatly improved over the years , their efficiency , as defined by live birth rate , is still only about 30 - 40% . consequently , many c...
despite many recent advances in the field of reproductive biology and medicine , the efficiency of in vitro fertilization procedures remains relatively low . there is a need for a reliable and non - invasive method of embryo selection to ensure that only embryos with the highest developmental potential are chosen for...
avaliar os efeitos da administrao sistmica precoce e tardia de metilprednisolona nos pulmes em um modelo de morte enceflica em ratos . vinte e quatro ratos wistar machos foram anestesiados e randomizados em quatro grupos ( n = 6 por grupo ) : sham , somente morte enceflica ( me ) , metilprednisolona i.v . ( 30 mg /...
objective : to evaluate the effects that early and late systemic administration of methylprednisolone have on lungs in a rat model of brain death . methods : twenty - four male wistar rats were anesthetized and randomly divided into four groups ( n = 6 per group ) : sham - operated ( sham ) ; brain death only ( bd ) ...
neuropsychiatric manifestations are included : p0 eripheral neuropathy , myeloneuropathy , cerebellar ataxia , optic atrophy , mood disorders , psychosis , personality changes , loss of memory , depression , dementia , confusion and more rarely reversible manic and schizoferniform status and obsessive compulsive disord...
b12 acts as a cofactor in synthesis of neurotransmitters such as serotonin and dopamine , thus b12 deficiency affects mood , emotions and sleeping and can lead to psychiatric disorders . psychiatric manifestations of b12 deficiency are varied . they seldom precede anemia . we want to present a case of b12 deficie...
the general population is exposed to palladium ( pd ) due to inhalation and contact with jewelry and especially dental restorations.1,2 although the use of palladium in dentistry had been described already in 1933,3 its wide - scale use started in the early 70 's due to the increasing gold price demanding the use of ot...
purposethe purpose of this study was to evaluate the effects of the surface treatment and shape of the dental alloy on the composition of the prosthetic work and its metallic ion release in a corrosive medium after casting.materials and methodsorion argos ( pd - ag ) and orion vesta ( pd - cu ) were used to cast two cr...
the human intestinal microbiota is a complex community composed of at least several hundred different species of bacteria with approximately 1010 cells per gram of feces [ 14 ] . the intestinal microbiota plays a critical role in human health including colonization resistance , nutrition , metabolism of nondigest...
a stable intestinal microbiota is important in maintaining human physiology and health . although there have been a number of studies using in vitro and in vivo approaches to determine the impact of diet and xenobiotics on intestinal microbiota , there is no consensus for the best in vitro culture conditions for grow...
to investigate potential movements of ssb on ssdna , we employed single molecule fluorescence resonance energy transfer ( smfret)8,9 . fret efficiencies e from individual immobilized partial duplex dna with a 3 ( dt)n tail ( 64 n 131 ) bound to ssb were acquired using total internal reflection fluorescence microsco...
single stranded ( ss)dna generated in the cell during dna metabolism is stabilized and protected by binding of single stranded dna binding ( ssb ) proteins . e. coli ssb , a representative homotetrameric ssb , binds to ssdna by wrapping the dna using its four subunits . however , such a tightly wrapped , high affin...
the goals of our course are two - fold : one goal is to expose students to research in major areas of psychology and a second goal is to present students with the many facets of being a scientist , with emphasis on the particular challenges experienced by women in science ( see table 1 for a synopsis of topics covered ...
we describe using biographies in teaching a course about the intrapersonal and interpersonal dynamics of science , with an emphasis on the professional and personal experiences of women in science . in our course , life of a psychologist : experiences of women in science , students examine biographies and scientific ...
walnut tree ( juglans regia l. ) , belongs to family juglandaceae ( 1 ) . walnut contains up to 62% - 68% oil , containing a high amount of monounsaturated and polyunsaturated fatty acids ( 2 ) . walnut leaves are considered as a source of healthcare compounds and are intensely used in traditional medicine to treat...
backgroundwalnut hydrosol ( wh ) is used extensively by iranian people with diabetes in order to control blood sugar ( bs ) . there are few data regarding the effect of walnut on controlling diabetes.objectivesa pilot study to determine the efficacy and safety of wh in patients with type 1 diabetes.materials and meth...
for many years stock raising has been an important part of livelihood and culture in sub - saharan africa [ 13 ] . the economic burden of livestock diseases and the declining provision of conventional veterinary services in this continent have undermined the efficiency of livestock production , especially by fulani p...
ethnoveterinary practices are locally available and affordable to fulani pastoralists in niger state , nigeria , to whom conventional veterinary services are often not readily available and are relatively expensive . this study was designed to identify and document medicinal plant and nonplant materials used by this ...
the birth of a baby with a tail can cause tremendous psychological disturbance to the parents . isolated case reports of various types of human tails have been described in the literature . the main features and imaging findings of six patients have been summarised in table 1 . the plain radiographs showed spina ...
human tail is a curiosity , a cosmetic stigma and presents as an appendage in the lumbosacral region . six patients of tail in the lumbosacral region are presented here to discuss the spectrum of presentation of human tails . the embryology , pathology and treatment of this entity are discussed along with a brief r...
alprazolam has antidepressant activity and has been shown to be similar in efficacy to imipramine in the treatment of unipolar depression in humans . thus , alprazolam may be particularly useful in patients with mixed anxiety / depression . however , its general acceptance as an antidepressant awaits further study . ...
alprazolam is an anti - anxiety drug shown to be effective in the treatment of depression . in this study , the effect of sympathetic receptor antagonists on alprazolam induced antidepressant action was studied using a mouse model of forced swimming behavioral despair . the interaction of three sympathetic recepto...
diabetic macular edema ( dme ) results from the exuding and accumulation of extracellular liquid and proteins in the macula13 following structural changes to the endothelium of the retinal blood vessels that lead to the rupture of the hematoretinal barrier and thus to an increase in vascular permeability.4 the patholog...
backgroundto evaluate the efficacy and safety of an intravitreal dexamethasone implant ( ozurdex ; allergan inc , irvine , ca , usa ) in patients with persistent diabetic macular edema ( dme ) over a 6-month follow - up period.methodsseventeen patients ( 20 eyes ) affected by dme were selected . the mean age was 67 +...
invasive fungal infections ( ifd ) are increasingly recognized and represent a primary cause of morbidity and mortality in critically ill patients [ 1 - 4 ] . a variety of factors , including immunosuppressive agents , broad - spectrum antibiotics , and antineoplastic agents influence the incidence and severity of ifds...
aspergilli , less susceptible to antifungals emerge and resistance to azoles have been found mainly in aspergillus fumigatus ; this has launched a new phase in handling aspergillosis . resistant strains have currently been reported from belgium , canada , china , denmark , france , norway , spain , sweden , the nethe...
the human species can be considered as relatively infertile ( viudes - de - castro and vicente , 1997 ; moce et al . , 2005 ) . the average monthly fecundity rate of about 20% implies that among human couples trying to conceive many exposure months may be needed to achieve their goal ( evers , 2002 ) . it has also ...
age related fertility decline varies considerably among women . therefore , chronological female age , though informative on pregnancy prospects in assisted reproduction , will often not correctly express a woman s reproductive potential . the value of quantitative ovarian reserve tests prior to ivf / icsi treatment ...
it has been well documented that a high prevalence of myopia exists in east asia and the western pacific regions [ 15 ] , and studies have indicated that myopia is an independent risk factor for primary open angle glaucoma ( poag ) [ 68 ] . however , making a glaucoma diagnosis can sometimes be particularly difficult i...
the aim of the current study was to investigate the association between the thickness of the retinal nerve fiber layer ( rnfl ) and central visual field indices in otherwise healthy myopes . in total , 57 otherwise healthy subjects were cross - sectionally studied . general ophthalmic examinations , refractive meas...
gaucher disease type 1 ( gd1 ) is an inherited lysosomal storage disorder characterized by deficient activity of the enzyme acid -glucosidase . as a result , glucosylceramide accumulates primarily in lysosomes of tissue macrophages leading to multisystem manifestations , including hepatosplenomegaly , anemia , thromb...
eliglustat is a recently approved oral therapy in the united states and europe for adults with gaucher disease type 1 who are cyp2d6 extensive , intermediate , or poor metabolizers ( > 90% of patients ) that has been shown to decrease spleen and liver volume and increase hemoglobin concentrations and platelet counts i...
tobacco smoke is a complex mixture of more than 4500 chemicals , many of which have toxic and/or carcinogenic activity . some of the components , which could be in the form of gases , vapors , and particulates , include carbon monoxide , hydrogen cyanide , phenols , acrolein , ammonia , formaldehyde , nicotine , nitr...
background : cigarette smoking is a worldwide social epidemic and it is one of the main causes of preventable death and disability . gingivitis , periodontitis , pocket depth , attachment loss , alveolar bone loss , and tooth loss are some of oral pathologies commonly found in cigarette smokers . the aim of this st...
in order to assess the abilities of alveolar macrophages ( ams ) to phagocytize adsorbent - adsorbate complexes , rat ams were incubated in vitro with two carbon blacks that have 15-fold differences in specific surface areas ( astm classification n339 less than black pearls 2000 ) sorbed with 0.5 and 1.0 monolayer cove...
there is a pressing need for obesity interventions to address the growing prevalence of excess weight in the usa , especially among hispanics , one of the fastest growing racial / ethnic groups in america . obesity is a common condition with associated risks of morbidity and mortality . according to data from the tex...
backgroundlittle is known concerning hispanic patients perceptions about the role of the physician in obesity management . this study seeks to describe the perspectives of hispanic patients toward weight loss , and what they believe their doctor s role should be in the management of obesity.methodsa cross - sectional...
recognition of the large numbers of chemicals in commerce and increased focus on evaluation of these chemicals from the perspective of potential human health risk has become a focus of attention in north america and europe . these efforts are devoted not only to evaluation of new chemicals but also to an examinatio...
evaluation of a larger number of chemicals in commerce from the perspective of potential human health risk has become a focus of attention in north america and europe . screening - level chemical risk assessment evaluations consider both exposure and hazard . exposures are increasingly being evaluated through biomo...
spinal epidural abscesses ( seas ) are unusual bacterial infections requiring prompt diagnosis and management to prevent devastating neurologic sequelae . they represent about 7% of vertebral infections and usually occur in subjects with predisposing underlying diseases or conditions such as diabetes mellitus , chron...
spinal epidural abscesses ( seas ) are unusual bacterial infections , with possible devastating neurologic sequelae . despite abundance of case series in adults , reports in children are scanty.we describe a spontaneous sea due to methicillin susceptible staphylococcus aureus ( mssa ) in a previously healthy 15-year ol...
as glycemic control deteriorates over time , treatment intensification with the addition of multiple oral antihyperglycemic agents is often required in patients inadequately controlled with monotherapy . polypharmacy and complexity of the treatment regimens are associated with poor adherence to treatment , which in t...
objective . to evaluate the differences in treatment compliance with vildagliptin / metformin fixed - dose versus free - dose combination therapy in patients with type 2 diabetes mellitus ( t2 dm ) in greece . design . adult patients with t2 dm , inadequately controlled with metformin monotherapy , ( 850 mg bid )...
its severe forms ( hemorrhagic fever and shock syndrome ) may lead to multiorgan involvement and death . dengue shock syndrome ( dss ) is characterized by a massive increase in systemic capillary permeability with consequent hypovolemia . the mortality rate in dengue shock syndrome ranges from 6 to 30 percent , mos...
dengue shock syndrome is the most severe form of dengue that can be fatal . nonresponders to standard therapy need intensive care . this paper outlines the clinical features , complications , and outcomes of dengue shock syndrome not responding to standard therapies and needing supportive care in a tertiary referra...
this genus comprises of gram - negative , strictly - aerobic , non - fermenting , non - fastidious , non - motile , catalase - positive , oxidase - negative bacteria with dna g + c content of 39.0% to 47.0% . according to euzeby 's list of prokaryotic names with standing in nomenclature ( http://www.bacterio.cict.fr/...
the genus acinetobacter consists of 31 validly published species ubiquitously distributed in nature and primarily associated with nosocomial infection . we report the 4.8 mb genome of acinetobacter guillouiae msp 4 - 18 , isolated from a mangrove soil sample from parangipettai ( 1130n , 7947e ) , tamil nadu , india ...
epistaxis ( bleeding from nose ) in children is generally traumatic in origin , the most common site of bleed being little 's area . besides trauma that generally occurs due to finger nails eroding the nasal mucosa , there are several tumors which can present with epistaxis . we report the first case in literature ...
pituitary tumour have a wide way of presentation . epistaxis due to pituitary adenoma has been rarely reported . there is no report of bleeding from nose as clinical first presentation in a child . we report the first case in literature where a child had epistaxis for eight months before deterioration of vision ....
the development of nanotechnology and microsystems has relied , in many ways , on the major progresses accomplished in surface science and materials science . in the past , much effort has been devoted to characterizing the optical , electrical , and magnetic characteristics of the resultant structures and devices . ...
details of berkovich nanoindentation - induced mechanical deformation mechanisms of single - crystal si(100 ) and the metal - organic chemical - vapor deposition ( mocvd ) derived gan thin films have been systematic investigated by means of micro - raman spectroscopy and cross - sectional transmission electron microsco...
between june 1998 and december 1999 , a total of 247 patients with new diabetic foot ulcers and without previous major amputation presented to the study center . they were included in this prospective study and followed up until 31 may 2011 , or until death . seventy - nine patients ( 32.0% ) were treated by the di...
objectivethere is a dearth of long - term data regarding patient and limb survival in patients with diabetic foot ulcers ( dfus ) . the purpose of our study was therefore to prospectively investigate the limb and person survival of dfu patients during a follow - up period of more than 10 years.research design and met...
taekwondo is a traditional korean martial art currently practiced in over 206 countries around the world1 and has high - profile educational and physical values2 . due to its various kicking and efficient attacking techniques3 , taekwondo has become a globalized sport and finally obtained full status in the o...
[ purpose ] the present study aims to provide fundamental information on injuries in taekwondo by investigating the categories of injuries that occur in taekwondo and determining the locations of these injuries . [ subjects and methods ] the data of 512 taekwondo athletes were collected . the sampling method ...
ischemia - reperfusion injury ( iri ) is a phenomenon whereby cellular damage in a hypoxic organ is accentuated following the restoration of oxygen delivery . in the liver , this form of injury is recognized as a clinically important prolonged disorder.1 liver iri occurs as a result of some liver surgeries , liver tran...
ischemia - reperfusion ( i / r ) injury is a multifactorial process that affects graft function after liver transplantation . an understanding of the mechanisms involved in i / r injury is essential for the design of therapeutic strategies to improve the outcome of liver transplantation . the generation of reactive...
crohn 's disease ( cd ) is a form of inflammatory bowel disease ( ibd ) that primarily affects the caucasian population [ 1 , 2 ] . therefore , identification of gene risk factors of cd is beneficial for the clinical treatment of patients . interleukin 23 ( il-23 ) plays an important role in the inflammatory respon...
the association between interleukin-23r gene polymorphism and crohn 's disease ( cd ) in caucasians is still controversial . thus , a meta - analysis was performed to evaluate the correlation between this gene variant and cd risk . we retrieved the available data from embase and pubmed until may 1 , 2014 , and eval...
development of methods to evaluate certain classes of polycyclic aromatic compounds ( pac ) detected in complex mixtures to which humans are exposed would greatly improve the diagnostic potential of 32p - postlabeling analysis . identification of dna adduct patterns or specific exposure - related marker adducts would...
the term of the global budget system started to appear in medical literature since 50 years ago . the global budget system indicates a payment method by which hospitals are allotted a specific amount of money and are then free to distribute the funds according to their individual priorities . although initial purp...
background : this study aimed to investigate dentists supply and practice patterns following the implementation of the global budget system in taiwan.materials and methods : data of reimbursement claims , municipal socioeconomic status and dental manpower were collected from the national health insurance administration...
the patients rights movement have promoted patient involvement in health care for 50 years ( 1 ) . patients rights encompass legal and ethical issues in the provider - patient relationship , including a person s right to privacy , the right to quality medical care without prejudice , the right to make informed decisi...
addressing patients rights issues brings occupational therapists ethical and political responsibilities that involve patients privileges and new facilitating factors which influence their needs . the goal of this study was to determine the level of occupational therapists knowledge about patients rights.the present r...
taken into account the spermatozoa , cryopreservation has several applications , such as seminal storage prior to prostate and vasectomy surgeries , before chemotherapy and radiotherapy treatments , prior to fertility treatments and for donor sperm banking ( 1 ) . however , sperm freezing and thawing processes lead to ...
background : leptin and its receptor are present in spermatozoa ; however , the role of leptin in sperm function is still controversial . our present study aimed at demonstrating the effect of cryopreservation on sperm dna fragmentation ( dnaf ) and investigating the possible effects of sperm capacitation techniques an...
studies were performed in 14 lean ( bmi 22 1 kg / m ) , healthy volunteers ( 7 male and 7 female ) , aged 1835 years without a personal or family history of hypertension or diabetes and receiving no medications . the studies were not scheduled to correspond to a particular phase of the menstrual cycle in the 7 femal...
objectiveto test whether early , insulin - mediated microvascular recruitment in skeletal muscle predicts steady - state glucose metabolism in the setting of physiological elevation of free fatty acid concentrations.research design and methodswe measured insulin s microvascular and metabolic effects in 14 healthy young...
modern out - of - hospital emergency medical services ( ems ) systems , as we have come to recognize them today , were established in the 1960s and 1970s when a cadre of intrepid physicians ventured into the streets and later published their successful experiences with lifesaving approaches to managing acute coronary s...
this article is one of ten reviews selected from the annual update in intensive care and emergency medicine 2015 and co - published as a series in critical care . other articles in the series can be found online at http://ccforum.com/series/annualupdate2015 . further information about the annual update in intensive...
coronary artery perforation ( cap ) which occurs either during or following percutaneuous coronary intervention ( pci ) is an infrequent complication , but one of the most disastrous complications of this cardiovascular surgery procedure.1 - 9 ) it has been related to vessel wall penetration with guidewire , balloon ov...
coronary artery perforation ( cap ) after percutaneous coronary intervention is a rare , but serious complication . it can cause cardiac tamponade , acute myocardial infarction or death . the treatments of cap involve prolonged balloon inflation , emergent surgery , coil embolization , and implantation of covered s...
plants have been considered as sources of medicinal agents for the treatment of various diseases such as malaria , leprotic ulcer , skin infections , high blood pressure . in our earlier work , we reported the effect of rauwolfia vomitoria root bark extract on the activities of cardiac enzymes and how this plant extr...
background : vitamin supplementation in rauwolfia vomitoria root bark extract administration may interact and impact significantly on hematology of albino wistar rats.aim:in this investigation we studied vitamin e supplementation with rauwolfia vomitoria root bark extract on the hematology of experimental animals.mater...
rett syndrome is a childhood neurodevelopmental disorder usually caused by a mutation in the gene encoding mecp2 located on the x chromosome ( xq28).1 rett syndrome occurs predominately in females although males have been described with mecp-2 mutations.2 stereotyped movement of the hands such as wringing , washing , h...
patients with rett syndrome are known to respond well to music irrespective of their physical and verbal disabilities . therefore , the relationship between auditory rhythm and their behavior was investigated employing a two - dimensional motion analysis system . ten female patients aged from three to 17 years were...
pancreatic transplants are performed worldwide for type i diabetes with renal failure and have shown to improve survival and quality of life . most of the reports are from countries with established organ donation programmes , but increasing awareness on organ donation in india could lead to an increase in the use of...
pancreatic grafts have been successfully used in patients with diabetes and are combined with kidney transplantation in patients with renal failure . the propagation of awareness in organ donation in india has increased the donor pool of transplantable organs in the last few years making multi visceral transplants fe...
the aim of this study was to evaluate the incidence and etiology of maxillofacial fractures and also to evaluate different treatment modalities . the sample consisted of 1,038 patients , with maxillofacial injuries treated at our center from june 2006 to june 2011 . cause , type , site of injury , gender , age and ...
objectives : the aim of this study was to evaluate the incidence and etiology of maxillofacial fractures and also to evaluate different treatment modalities.study design : the sample consisted of 1,038 patients , with maxillofacial injuries treated at our center from june 2006 to june 2011 . cause , type , site of in...
most cases of hematuria can be diagnosed by urinalysis , urine culture , urinary cytology , computed tomography , and rigid and flexible cysto - ureteroscopy . we present a rare cause of hematuria that was challenging both to diagnose and to treat . a 50-year - old woman presented with a 1-month history of painless...
a 50-year - old woman presented with gross hematuria for 1 month . clinical examinations , laboratory investigations , ultrasound and contrast computed tomography were normal , except anemia . cystoscopy revealed bloody efflux from the right side . retrograde pyelogram showed filling defect in the renal pelvis an...
nasal dermoid sinus cysts ( ndsc ) are the most common congenital midline nasal lesion , accounting for 1% to 3% of all dermoid cysts , and 4% to 12% of head and neck dermoids ( 1 , 2 ) . ndscs may appear as a cystic mass or sinus opening on the midline nasal dorsum between the glabella and the columella at birth , or ...
nasal dermoid sinus cysts are the most common congenital midline nasal lesion , accounting for 1% to 3% of all dermoid cysts , and 4% to 12% of all head and neck dermoids . selection of the appropriate reconstruction technique , after dermoid resection , is important for treatment . here we describe the successful ...
in the last decade repair of mrna by spliceosome - mediated rna trans - splicing has raised interests as a novel therapeutic intervention ( for reviews , see refs . ) . trans - splicing has many attractive features such as preservation of the endogenous regulation , replacement of selected portions of the target gene...
rna trans - splicing has been explored as a therapeutic option for a variety of genetic diseases , but not for cardiac genetic disease . hypertrophic cardiomyopathy ( hcm ) is an autosomal - dominant disease , characterized by left ventricular hypertrophy ( lvh ) and diastolic dysfunction . mybpc3 , encoding cardia...
papillary thyroid carcinoma being the most common type of differentiated thyroid malignancy has a predilection for spread through the lymphatic system and thus commonly involves the central and lateral compartmental lymph nodes of the cervical region . soft tissue metastasis is even rarer and amenable to radioiodine ...
distant soft tissue metastasis and the simultaneous presence of iodine concentrating and nonconcentrating lesions in papillary thyroid cancer are extremely rare . the concerned patient , a histopathologically proven case of papillary thyroid cancer with nodal metastases treated with total thyroidectomy , bilateral cerv...
magnetic resonance imaging ( mri ) of the lung has been a challenge due to limitations such as low proton density in the lung and the fast signal decay due to susceptibility artefacts at air - tissue interfaces . thanks to recent technical advances such as parallel imaging , shared echo - technique and rotating phase...
backgroundmri of the lung is recommended in a number of clinical indications . having a non - radiation alternative is particularly attractive in children and young subjects , or pregnant women.methodsprovided there is sufficient expertise , magnetic resonance imaging ( mri ) may be considered as the preferential mod...
thrombolysis with recombinant tissue plasminogen activator ( rtpa , alteplase ) is the only effective specific treatment for acute ischemic stroke patients coming in window ( 4.5 h from onset of symptoms ) . a milestone study of national institute of neurological disorders and stroke in 1995 , demonstrated the benefi...
aim:(1 ) to evaluate the number of patients thrombolysed within 1 h of arrival to emergency room ( er ) ( 2 ) to identify reasons for delay in thrombolysis of acute stroke patients.materials and methods : all patients admitted to er with symptoms suggestive of stroke from january 2011 to november 2013 were studied . ...
prehypertension ( pht ) was first introduced by the seventh joint national committee on prevention , detection , evaluation , and treatment of high blood pressure ( jnc-7 ) in 2003 , replacing former categories of high - normal and above - optimal blood pressure ( bp ) ; and it was defined as systolic bp of 120139 ...
introduction . the purpose of this observational cross - sectional study was to assess left ventricular mass ( lvm ) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure ( bp ) correlates better with lvm index ( lvmi ) than brachial bp . methods and result . bra...
respiratory diseases such as asthma are becoming increasingly prevalent , with reduced longevity and quality of life for those affected as well as causing an economic burden upon healthcare systems worldwide . consequently , there is a need to develop more effective therapies to prevent and treat respiratory ...
the development of more complex in vitro models for the assessment of novel drugs and chemicals is needed because of the limited biological relevance of animal models to humans as well as ethical considerations . although some human - cell - based assays exist , they are usually 2d , consist of single cell ty...
a denoid cystic carcinoma ( acc ) is a malignant neoplasm of the salivary glands . the term adenoid cystic carcinoma was coined in the year 1928 and is in use till date . adenoid cystic carcinomas constitute less than 1% of all head and neck malignancies with 50% of all accs occurring intraorally , commonly in the...
adenoid cystic carcinomas are deceptive malignancies that show slow growth and local invasion with recurrences seen many years after diagnosis . upto 50% of these tumors occur in the intraoral minor salivary glands usually in the hard palate . buccal mucosal tumors are relatively rare . we determined the incidenc...
in adults , damaged cartilage has a very limited capacity for self - healing due to the absence of blood vessels , the low intrinsic density of chondrocytes , and the low turnover of the extracellular matrix . the absence of stem cells and the low capacity of resident chondrocytes to migrate and proliferate also redu...
as medical advances lengthen average life expectancy , osteoarthritis ( oa ) will become a larger public health problem - not only because it is a manifestation of aging but also because it usually takes many years to reach clinical relevance . oa is already one of the ten most disabling diseases in industrialized co...
ten different brands of stps were collected from the local retail markets of cochin ( kerala ) from the months of august to november 2011 . the samples were selected on the basis of popularity among the people especially the teenage community , representing a large and uniform sample pool . they were personally col...
the characterization and classification of smokeless tobacco products has been a continuously evolving process . this is based on a number of different parameters like nicotine content , moisture content , amount of heavy metals , ph , and in vitro cytotoxicity assays . their contexts often vary between countries ,...
the first nobel prize in physiology or medicine , like those in chemistry , physics , literature and peace , was awarded in 1901 . indeed , the twentieth century can be regarded as the century of the nobel prize . from the very outset , however , nobel prizes in general , and the one in physiology or medicine in pa...
the human genome project ( hgp ) is regarded by many as one of the major scientific achievements in recent science history , a large - scale endeavour that is changing the way in which biomedical research is done and expected , moreover , to yield considerable benefit for society . thus , since the completion of the ...
varicella zoster virus ( vzv ) is one of the most prevalent viruses which affects the human race ( 1 ) . primary infection known as chickenpox , mostly occurs in childhood , with mild clinical course in immunocompetent hosts , but it can cause significant morbidity in healthy adults with life threatening forms in imm...
objective : to investigate possible prognostic values of cd4 + , cd8 + t - lymphocytes , cd4/cd8 ratio to clinical course of chickenpox in immunocompetent hosts.materials and methods : we performed a prospective study which included 69 immunocompetent patients with chickenpox who were addmited to clinic for infectious ...
the authors present a case of giant ureteric calculus highlighting the importance of plain film radiograph in the assessment of children with suspected renal tract calculi . ultrasonography demonstrated left hydronephrosis and a 2 cm echogenic area with acoustic shadow in the proximal ureter , consistent with a urete...
giant ureteric calculi are extremely rare in children . we present a case of a child who was originally admitted for observation following non - accidental injury and had an episode of painless haematuria as an inpatient . ultrasonography demonstrated left hydronephrosis and a 2 cm echogenic area in the proximal ur...
interactions between hormonal contraceptives and antiretroviral ( arv ) medications to treat hiv are of great importance.1 in 2009 , approximately 1.2 million people in the united states were living with hiv.2,3 globally , the scope of the problem is more decimating , as hiv / aids is the leading cause of death among w...
objective : pharmacokinetic interactions exist between combined oral contraceptives and protease inhibitors ( pi ) . however , such information is lacking for progestin - only oral contraception . we sought to define the steady - state pharmacokinetic interaction between norethindrone ( net ) and pi in hiv - infect...
details of the step study design have been reported previously ( 1820 ) . in brief , this was a 12-month , cluster - randomized clinical trial designed to assess the use of structured smbg , as part of a comprehensive , collaborative intervention , on glycemic control compared with enhanced usual care in 483 patients w...
objectivethe effect of therapeutic strategies on cardiovascular ( cv ) disease can be evaluated by monitoring changes in cv risk biomarkers . this study investigated the effect of a structured self - monitoring of blood glucose ( smbg ) protocol and the resulting improvements in glycemic control on changes in high - ...
impaired upper urinary tract urine flow is often caused by ureter obstruction due to retro - peritoneal metastatic cancer . obstruction generally begins with pain , then with loss of renal function due to long - lasting congestion , acute or chronic renal insufficiency and/or hydronephrosis of the infected kidneys an...
introductionureter obstruction caused by a retro - peritoneal tumor is treated by inserting an indwelling ureter splint ( dj - stent ) . indwelling duration is limited by cumulative crystalline deposits into the splint , eventually causing the repeated impairment of urine flow . deciding when a dj - stent must be r...
recent data from routine clinical practice shows that once - daily prolonged - release formulations of tacrolimus result in improved graft survival in liver transplant recipients relative to twice - daily immediate - release tacrolimus.based on these data , a model was constructed to estimate life expectancy , numbers ...
backgroundas of 2014 , there were approximately 8300 patients with a functioning liver transplant in the uk transplant registry , with 880 liver transplants performed in 20132014 alone . tacrolimus , typically used in combination with steroids and mycophenolate mofetil , currently represents the cornerstone of post -...
wrist injuries caused by fatigue at work or improper exercise are very common . for example , carpal tunnel syndrome , cubital tunnel syndrome , stenosing tenosynovitis , stenosing tenosynovitis of the flexor tendons , locked finger , thecal cyst , and other symptoms cause great trouble for patients , because i...
[ purpose ] the introduction of emerging technologies such as the wireless blobo bluetooth ball with multimedia features can enhance wrist physical therapy training , making it more fun and enhancing its effects . [ methods ] wrist injuries caused by fatigue at work , improper exercise , and other conditions are ...
as the older adult population grows , the number of older drivers also increases . these drivers tend to drastically reduce the amount that they drive , since many are retired and have a limited range of everyday and economic activities . additionally , drivers abilities are affected by their normal aging as well...
[ purpose ] to evaluate the sensitivity and specificity of the safe driving behavior measure and the driving habits questionnaire in community - dwelling older self - drivers . [ subjects and methods ] forty - five older participated in this study , to measure the safe driving behavior measure and the driving hab...