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cardio pulmonary resuscitation ( cpr ) is an emergency procedure performed on people under cardiac arrest and on people who stop breathing due to reasons such as drowning . cpr 's main benefit is that it maintains blood flow , which prevents tissue and brain damage . the procedure involves creating artificial blood...
timely cardio pulmonary resuscitation ( cpr ) can mean the difference between life and death . a trained person may not be available at emergency sites to give cpr . normally , a 9 - 1 - 1 operator gives verbal instructions over the phone to a person giving cpr . in this paper , we discuss the use of smartphones to...
there are 20 class i genes and in transplantation hla - a , b , and c are the classic genes referenced to when typing the recipient . class i major histocompatibility complex ( mhc ) molecule processing and loading of peptides occurs in all nucleated cells , where class ii mhc molecule involves primarily b cells , ma...
antibody - mediated rejection ( amr ) is a major cause of late kidney transplant failure . it is important to have an understanding of human - leukocyte antigen ( hla ) typing including well - designed studies to determine anti - mhc - class - i - related chain a ( mica ) and antibody rejection pathogenesis . this ...
science aims to provide simple and general explanations for natural phenomena , and all sciences must deal with the problem of heterogeneity . variation and heterogeneity are the hallmarks of biological diversity and capture the attention of anyone interested in trying to unravel the mysteries of the biological world...
the protein electrophoresis revolution , nearly fifty years ago , provided the first glimpse into the nature of molecular genetic variation within and between species and showed that the amount of genetic differences between newly arisen species was minimal . twenty years later , 2d electrophoresis showed that , in c...
assemble the chamber ( design illustrated in figure 1 ) . place two beads of vacuum grease , spaced ~8 - 10 mm apart , across the recording chamber to form a channel for superfusate and in which to embed the retinal slices . add a second bead of grease a few millimeters farther out beyond each of these two beads of g...
one of the central tasks in retinal neuroscience is to understand the circuitry of retinal neurons and how those connections are responsible for shaping the signals transmitted to the brain . photons are detected in the retina by rod and cone photoreceptors , which convert that energy into an electrical signal , tran...
. high rate of spontaneous remissions is known in patients with early disease that present constellation of specific features called lfgren 's syndrome . on the other hand , an insidious onset of the disease without lfgren 's syndrome sarcoidosis progression has not been associated with any particularly specific immu...
purpose . pulmonary sarcoidosis is associated with dysregulated expression of intracellular mirnas . there is however only little information on extracellular mirnas and their association with the disease course in sarcoidosis . we therefore assessed serum mirnas in sarcoidosis classified according to the presenc...
thyroid cancer accounts for 12% of all malignancies , representing the most common endocrine malignancy . papillary carcinoma ( ptc ) is the most frequent among thyroid malignancies , whereas medullary thyroid carcinoma ( mtc ) accounts for 510% of cases . mtc , on the other hand , originates from parafollicular ce...
introductiona few cases of concomitant medullary and papillary carcinoma in the same thyroid nodule have been described in the literature . however , the presence of multiple foci of both types of malignancy in the same gland is very rare.presentation of casea 39 year - old female with multiple thyroid nodules , elevat...
there is no definition of treatment - resistant bipolar depression in the literature . the international society for bipolar disorders ( isbd ) task force published their consensus definition of treatment response in bipolar depression1 and proposed a nomenclature for relapse , remission , and recurrence , but did not ...
adjunctive use of methylphenidate , a central stimulant , has been considered as a potential therapeutic choice for patients with refractory unipolar , geriatric , or bipolar depression , and depression secondary to medical illness . we present a case of bipolar depression in which the patient responded significantly...
since childers et al initially reported the laparoscopic surgical management of 2 cases of stage i endometrial cancer , many studies have advocated the advantages of laparoscopically assisted staging surgery ( lass ) compared with laparotomic staging surgery in women with endometrial cancer . laparoscopic surgical ma...
background and objective : in recent years , the incidence of endometrial cancer has gradually increased in korea , and the use of laparoscopically assisted staging surgery ( lass ) is increasing in this field . we conducted this study to evaluate the feasibility of lass in korean women with endometrial cancer.method...
a literature search was performed up to march 2011 in 13 international databases : african index medicus , anthropology plus , british nursing index and archive , the cochrane library , embase , epoc , medline , pilots , popline , psycinfo , social services abstracts , sociological abstracts , and wholis . it was sup...
understanding the forces underpinning female genital mutilation / cutting ( fgm / c ) is a necessary first step to prevent the continuation of a practice that is associated with health complications and human rights violations . to this end , a systematic review of 21 studies was conducted . based on this review , th...
overweight and obesity have been defined as abnormal or excessive accumulations of fat in the body that may impair health . overweight and obesity results from an energy imbalance in the amount of calories consumed and the amount of calories expended . the rise of overweight and obesity globally has been attributed...
objective . to examine the association between socioeconomic factors and weight status across 53 countries . methods . data are cross - sectional and from the long version of the world health survey ( whs ) . there were 172,625 whs participants who provided self - reported height and weight measures and sociodemograp...
proliferating cell nuclear antigen ( pcna ) serves as a processivity factor ( sliding clamp ) , encircling dna at sites of replication and repair ( 15 ) . the subunits come together to form a remarkable ring - like structure with characteristic pseudo 6-fold symmetry and a central hole large enough to accommodate dou...
proliferating cell nuclear antigen ( pcna ) acts as a biologically essential processivity factor that encircles dna and provides binding sites for polymerase , flap endonuclease-1 ( fen-1 ) and ligase during dna replication and repair . we have computationally characterized the interactions of human and archaeoglobus...
patients admitted to kitunan hospital in suzenji , japan from may 1999 and april 2007 with acute psychomotor excitation were studied retrospectively . the inclusion criteria were : ( i ) patients diagnosed with schizophrenia according to the diagnostic and statistical manual of mental disorders , 4th edition ( dsm - ...
during treatment of acute - phase schizophrenia , attention needs to be given to physical as well as psychological symptoms . it is often difficult , however , to obtain information on physical symptoms from patients with psychomotor excitation , and only laboratory examinations can provide objective data . the res...
however many people refuse it because of fear of needle and back pain.1 many techniques have been used to obtund pain of needle insertion including infiltration analgesia and emla patch . local anesthetics themselves may produce pain on injection and many anesthetists are unsure that infiltration analgesia at the sit...
this study evaluated the efficacy of the valsalva maneuver that can induce baroreceptor activation and nociception , on needle projection pain and hemodynamic responses associated with spinal puncture . ninety adults , asa physical status i and ii undergoing elective surgeries were included . patients were randomiz...
the essential function of a classification system is as a navigation tool that helps direct research , evaluate outcomes , establish guidelines for best practices for prevention and care , and educate on all of the above . diabetes mellitus ( dm ) subtypes as currently categorized , however , do not fit into our cont...
the current classification system presents challenges to the diagnosis and treatment of patients with diabetes mellitus ( dm ) , in part due to its conflicting and confounding definitions of type 1 dm , type 2 dm , and latent autoimmune diabetes of adults ( lada ) . the current schema also lacks a foundation that rea...
considering the rapidly burgeoning older population , increased attention is being given to an accurate assessment of older adults ' cognitive and neuropsychological functioning . part of this process involves obtaining a viable estimate of their premorbid cognitive ability or their expected performance prior to any ...
this study examines the utility of the american version of the national adult reading test ( amnart ) as a measure of premorbid intelligence for older adults . in a sample of 130 older adults , aged 56 to 104 , the amnart was compared to other tests of premorbid intelligence . the results revealed that amnart - est...
reaching these niches is sometimes a challenging feat as pathogens have to travel long distances across organs , cross several cellular barriers , invade cells and travel inside the cell itself . the talk by robert mnard ( pasteur institute , paris ) followed one of these journeys . it travels the blood stream and ...
the first embo workshop on emerging themes in infection biology was held last june in the south of france . it gathered scientists working on various pathogens from viruses and bacteria to larger eukaryotic fungi and parasites . topics included not only the crosstalk between pathogens and their hosts but also the t...
intussusception of the appendix is an uncommon type of intussusception with an incidence of 0.01% ( 1 ) . although it may clinically mimic more common acute and chronic abdominal conditions , it is an important entity to recognize since it could be discovered as cecal mass and mistaken for a neoplasm . in korea , t...
intussusception of the appendix is an uncommon condition and the diagnosis is rarely made preoperatively . intussusception of the appendix may mimic a neoplastic lesion . colonoscopy is a valuable tool for diagnosis of the appendiceal intussusception . a 17-yr - old female admitted with repeated abdominal pain , ...
an obvious example of a current debate within hoarding research is the question of where hoarding belongs within our diagnostic nosology . the uncertainty regarding the most appropriate classification of compulsive hoarding syndrome has had important consequences for our understanding of hoarding , and in some ways h...
compulsive hoarding is a disabling psychological disorder characterized by excessive collecting and saving behavior . this article reviews four key areas of recent advances in hoarding research . first , we provide an overview of the evolving controversy regarding the diagnostic status of hoarding , highlighting ac...
in middle - aged populations , differences between males and females are described in terms of various aspects of coronary artery diseases . males , for example , have a higher rate of previous myocardial infarction ( mi).1,2 females , at least in some studies , have been reported to have a longer delay to reach hosp...
objectivesthis study analyzed age - adjusted sex differences among acute myocardial infarction ( ami ) patients aged 75 years and above with regard to 7-year mortality ( primary end point ) and the frequency of angiograms and admission to the coronary care unit ( ccu ) as well as 1-year mortality ( secondary end points...
until recently , influenza a virus infection in indonesia did not cause much concern for the public due to the mild , self - limiting nature of seasonal influenza . however , since the outbreaks of avian influenza a ( h5n1 ) in poultry in 2003 and the subsequent fatal human infections in 2005 , the risk of influenza ...
indonesia has been part of the global influenza surveillance since the establishment of a national influenza center ( nic ) at the national institute of health research and development ( nihrd ) by the indonesian ministry of health in 1975 . when the outbreak of avian influenza a ( h5n1 ) occurred , the nic and us nava...
an estimated 569,490 americans are expected to die of cancer in 2010 , accounting for approximately 25% of the overall mortality 1 . bone metastases are a common manifestation of advanced disease with autopsy studies showing an incidence of 33 - 36% in patients with lung cancer 2 , 3 , 68% in prostate cancer 3 , and ...
response criteria represent the standard by which the efficacy of therapeutic agents is determined in cancer trials . the most widely used criteria are based on the anatomic measurement of solid tumors . because bone metastases are typically located in irregularly shaped bones and are difficult to measure with rule...
most cellular functions are carried out by a complex network of genes , proteins , and metabolites that interact through biochemical and physical interactions ( gerstein et al , 2002 ; barabsi and oltvai , 2004 ; albert , 2005 ; basso et al , 2005 ; almaas , 2007 ; alon , 2007 ; yildrim et al , 2007 ) . therefore , d...
the impact of disease - causing defects is often not limited to the products of a mutated gene but , thanks to interactions between the molecular components , may also affect other cellular functions , resulting in potential comorbidity effects . by combining information on cellular interactions , disease -- gene assoc...
bilateral sagittal split osteotomy ( bsso ) is one of the most common orthognathic surgical procedures for the correction of mandibular deformities . the obwegeser - dal pont osteotomy and hunsuck modifications are widely used1 - 3 . when performing bsso , it is crucial to control the lingual split because it may res...
objectivesthe aim of this study was to evaluate the pattern of lingual split line when performing a bilateral sagittal split osteotomy ( bsso ) for asymmetric prognathism . this was accomplished with the use of cone - beam computed tomography ( cbct ) and three - dimensional ( 3d ) software program.materials and meth...
despite the marked advances in the perioperative management of the liver transplant recipient , an assessment of clinically significant graft injury following preservation and reperfusion remains difficult . the lack of a sensitive clinical marker of acute liver injury has a profound impact on clinical practice and t...
background . despite the marked advances in the perioperative management of the liver transplant recipient , an assessment of clinically significant graft injury following preservation and reperfusion remains difficult . in this study , we hypothesized that size - adjusted ast could better approximate real ast values...
heart function fails when the organ is unable to pump blood at a rate proportional to the body s need for oxygen or when this function leads to elevated cardiac chamber filling pressures ( cardiogenic pulmonary edema ) . despite our sophisticated knowledge of heart failure , even the so - called ejection fraction up ...
heart function fails when the organ is unable to pump blood at a rate proportional to the body s need for oxygen or when this function leads to elevated cardiac chamber filling pressures ( cardiogenic pulmonary edema ) . despite our sophisticated knowledge of heart failure , even so - called ejection fraction - prese...
mutations of the gjb2 gene , encoding gap junction protein connexin 26 ( cx26 ) , are the most common cause of hereditary congenital hearing loss in many countries ( 2 ) . cx26 is a member of the connexin family of gap junction proteins , which facilitate intercellular communication by encoding channels that directly...
mutations in the gjb2 gene are the most common known cause of hereditary congenital hearing loss . rapid genomic dna extraction ( rgde ) method was used for genomic dna extraction . after amplification of coding region of cx26 gene with specific primers , expected pcr products with 724bp length were subjected to di...
linear growth retardation , or stunting , which is a manifestation of chronic malnutrition , is highly prevalent in under - developed and developing countries.[14 ] according to the world health organization , 215 million children were stunted in 2000 throughout the world . the national data from iranian national stu...
background : limited data are available indicating associates of stunting among iranian children . this study was conducted to investigate determinants of stunting in first grade primary school children of tehran in 2007.method:in this case - control study , 3147 school children were selected by multistage cluster ra...
already back in 1850 , ignatz semmelweis was able to demonstrate in a spectacular manner that hand hygiene could prevent infections , but since then very few studies have been able to attest to the importance of hand hygiene in everyday practice . it is therefore all the more remarkable that in two studies of simpl...
using two studies of a simple design it has been possible to furnish proof of the influence of hand hygiene prior to insertion of peripheral venous catheters on the incidence of complications . in the first study detailed data were collected anonymously for each patient on the procedure used for catheter insertion or o...
important factors determining the rate of tooth alignment include the bracket slot dimension , the associated inter bracket span , the choice of arch wire , and frictional forces generated between bracket and arch wire . friction has been defined as the resistance to motion that occurs when two objects move tangentia...
objectives : to conduct a prospective randomized study comparing the efficiency of 5 different ligation systems ( ell ; elastomeric ligature , ssl ; stainless steel ligature , ll ; leone slide ligature , psl ; passive self - ligation and asl ; active self - ligation ) over the duration of mandibular crowding alleviatio...
mucinous carcinoma of the breast is uncommon , the reported incidence of pure mucinous carcinoma being 2% of all breast cancers . pure mucinous carcinoma has a far better prognosis than the mixed variety noted in several studies . we report a case diagnosed as pure mucinous carcinoma breast on fine needle aspiratio...
mucinous carcinoma of the breast is a relatively rare , pure form accounting for 2% of all breast cancers . pure mucinous carcinoma of the breast has a favorable prognosis . the common age is postmenopausal group . here , we report a 30-year - old female patient diagnosed on cytology as mucinous carcinoma of the ...
for the pharmacometrician and the system pharmacologist , computer software is , quite simply , the equivalent of the laboratory for the molecular biologist , or of the research clinic for the practicing clinician . it is the environment where tools are developed , observations and conjectures are made , hypotheses a...
in addition to methodological tutorials,1 cpt : psp has recently started to publish software tutorials.2,3 our readership and authors may be wondering what kind of format or product is expected , and the review of submissions we have already received prompted several discussions within the psp editorial team . this e...
the institute of medicine ( iom ) report to err is human revealed the number and significance of adverse events and errors that occur during hospitalization . the report was a call to action to transform healthcare systems to ensure patient safety and higher quality care . in one step toward healthcare transforma...
the purpose of this study was to examine factors that contribute to adverse incidents by creating a model that included patient characteristics , clinical conditions , nursing unit context of care variables , medical treatments , pharmaceutical treatments , and nursing treatments . data were abstracted from electroni...
therefore , action must be taken immediately to diagnose and treat such intracranial complications before irreversible tissue damage has occurred , and both physicians and patients at putative risk should be aware . here , a case of sinusitis originating from an odontogenic focus leading to severe subdural empyema with...
key clinical messagesubdural empyema is a rare but potentially lifethreatening complication to sinusitis . awareness of infection and early diagnosis is of the essence when dealing with a putatively immunosuppressed patient . furthermore , patients at increased risk of infections due to immunosuppression need to be...
establishing good communication , either verbal or nonverbal , with patient is an essential and important component to develop a good doctor - patient relation . face - to - face interaction ( including facial expressions and eye contact ) , expressive touch , body language , paralinguistics ( vocal communication whi...
background . nonverbal behaviors have a significant impact on patients during consultations . this study was undertaken to find out the attitudes and preferences of the patients regarding nonverbal communication during consultations with physicians , in a tertiary care hospital . methods . a questionnaire based c...
ischemic colitis usually develops due to arteriosclerosis , diabetes , hypovolemic shock , portal hypertension , malignant tumors , pancreatitis , or colonic obstruction . it is very common in elderly people.1 phlebosclerotic colitis ( pc ) is a rare form of ischemic colitis that develops as a result of mesenteric ve...
phlebosclerotic colitis is a rare disease of intestinal ischemia and differentiating it from the typical ischemic colitis . it is caused by venous obstruction due to colonic and mesenteric venous calcification . we report a 36-year - old woman presenting with intermittent abdominal pain . initial radiologic findi...
soft tissue sarcomas are rare tumors ( 1% of all adult malignancies ) with a dismal prognosis . approximately 70% of sarcomas occur in the extremities ( 49% in the lower and 19% in the upper limbs ) , while the remaining 30% occur in the trunk , abdomen or retroperitoneum ( 1,2 ) . among the most common histological ...
soft tissue sarcomas are rare tumors with a dismal prognosis . among the most common histological types of sarcomas of the extremities , malignant fibrous histiocytoma ( mfh ) is the one with the highest incidence . surgery is considered to be the first choice of treatment for mfh . to the best of our knowledge , ...
nevus depigmentosus is a hypomelanotic condition which is usually refractory to medical modalities of treatment.a few cases of surgical repigmentation have been reported.one case report from south korea described the recurrence of hypomelanosis at the surgically treated site after eight years . nevus depigmentosus is...
nevus depigmentosus is a congenital hypomelanotic condition for which no effective treatments are available . the hypopigmentation is permanent and enlarges in proportion with growth in the person . here , i report a patient of nevus depigmentosus on whom we performed suction blister grafting and the resultant pigm...
in bone , endogenous nucleotides , such as atp and utp , are released from many types of cells , including bone cells [ 1 , 2 ] . nucleotides are released in response to a number of stimuli including inflammation [ 3 , 4 ] and mechanical stimulation [ 57 ] . they act as autocrine and paracrine signaling molecules b...
the purinergic p2x7 receptor is expressed by bone cells and has been shown to be important in both bone formation and bone resorption . in this study we investigated the importance of the genetic background of the mouse strains on which the p2x7 knock - out models were based by comparing bone status of a new balb / cj ...
we studied cross - sectionally clinic- and hospital - based adult diabetic patients ( aged > 30 years ) within 1 year from diagnosis . we ascertained subjects with lada and type 2 diabetes from the lada china multicenter study ( 46 hospitals throughout china contributed ) ; type 1 diabetes , defined by who criteria (...
objectiveto determine the relationship between selected cytokines and diabetes in chinese subjects.research design and methodsadult patients with recent - onset type 1 diabetes ( n = 53 ) , latent autoimmune diabetes in adults ( lada ) ( n = 250 ) , and type 2 diabetes ( n = 285 ) from multiple centers were compared wi...
azathioprine is a prodrug of the purine mimic antimetabolite , 6-mercaptopurine , widely used in various autoimmune diseases and organ transplantation . little is known about the pathogenesis and epidemiology of azathioprine - induced cholestatic hepatitis , a rare but dramatic iatrogenic complication . a 73-year -...
we report a case of cholestatic hepatitis developed one week after exposure to azathioprine . the subsequent prolonged cholestatic phase was followed by full clinical remission . current knowledge on pathogenesis and epidemiology and the diagnostic challenges presented by this rare complication are discussed , foll...
nocturia is defined as waking one or more times to void during the period between going to bed with the intention of sleeping and waking with the intention of arising ( 1 , 2 ) . recent multinational population - based , cross - sectional survey ( epic ) of adults aged 18 yr using 2002 international continence societ...
to investigate the efficacy and safety of desmopressin in patients with mixed nocturia , patients aged 18 yr with mixed nocturia ( 2 voids / night and a nocturnal polyuria index [ npi ] > 33% and a nocturnal bladder capacity index [ nbci ] > 1 ) were recruited . the optimum dose of oral desmopressin was determined ...
a 38-year - old female from puerto rico with complaints of hypoxia was transferred to our facility . she had been diagnosed 5 years earlier with hermansky - pudlak syndrome ( hps ) subtype 1 , complicated by pulmonary fibrosis . she had experienced a slow deterioration in pulmonary function , manifesting as worseni...
hermansky pudlak syndrome ( hps ) is a rare autosomal recessive disorder characterized by oculocutaneous hypopigmentation , platelet dysfunction , and in many cases , life - threatening pulmonary fibrosis . we report the clinical course , imaging , and postmortem findings of a 38-year - old female with hps - related...
the incidence rates of oral cancer are 3.7% for men and 2.6% for women in the sudan . several lifestyle risk factors for the development of oral cancer are familiar , including tobacco products , alcohol , infections , dietary factors , chemical irritants and frank carcinogens . prevalence of oral cancer is...
abstractobjectivesto review the studied risk factors that linked to aetiology of oral cancer in the sudan . there have been numerous reports in the increase in the incidence of oral cancer from various parts of the world . a recent trend for a rising incidence of oral cancer , with the absence of the well est...
understanding how the vertebrate nervous system develops from the embryonic ectoderm has been one of the most intensely investigated developmental processes . the process of neural induction was discovered by hans spemann and hilde mangold ; when dorsal mesoderm was transplanted adjacent to ventral ectoderm that no...
the early steps of neural development in the vertebrate embryo are regulated by sets of transcription factors that control the induction of proliferative , pluripotent neural precursors , the expansion of neural plate stem cells , and their transition to differentiating neural progenitors . these early events are cri...
heart failure is considered the last stage of heart disease and a significant cause of worldwide mortality and morbidity.1,2,3 the end - stage of heart failure , which is marked by a lack of response to medical treatment , disabling symptoms , and repeated hospital stays , is associated with high morbidity and mortalit...
objective : we sought to evaluate the neurohormonal activity in heart transplant recipients and compare it with that in heart failure patients and healthy subjects during rest and just after a 6-minute walking test.introduction:despite the improvements in quality of life and survival provided by heart transplantation ,...
we do not understand yet why some patients develop multiple myeloma and others a single plasmacytoma 1 , 2 , but that might be related to differences in the chemokine receptor expression profiles of the malignant plasma cells or cellular adhesion molecules 3 . solitary extramedullary plasmacytomas ( sep ) are extreme...
key clinical messageplasma cell neoplasms are characterized by a neoplastic plasma cell lineage which produces a monoclonal immunoglobulin . these neoplasms can present as a single lesion ( solitary plasmacytoma ) or as multiple lesions ( multiple myeloma ) . solitary plasmacytomas most frequently occur in bone ( p...
upper gastrointestinal bleeding ia a major emergency and represents a major public health problem , its prevalence being 100170:100000 people . bleeding from esophageal varices is only 511% of all gastrointestinal bleeding and in the u.s . approximately 30% of patients with compensated cirrhosis have esophageal var...
objectivesthe aim of this study was to monitor the risk factors that trigger variceal bleeding in cirrhotic patients , assess the severity of the bleeding and the efficacy of the endoscopic hemostasis techniques , as well as the recurrence of bleeding episodes and the mortality rate.materials and methodsthe current stu...
when ischemic stroke occurs , motor function is one of the most important brain functions to be protected together with language , sensory , visual , and hearing function . since the most motor cortex and motor neuron pathway are located in the middle cerebral artery territory , infarction of this territory causes co...
this study investigated the effect of bone marrow mesenchymal stem cells ( bmscs ) on the motor pathway in the transient ischemic rat brain that were transplanted through the carotid artery , measuring motor - evoked potential ( mep ) in the four limbs muscle and the atlantooccipital membrane , which was elicited after...
stroke refers to cerebrovascular bleeding and a neural disease caused by nontraumatic reasons and is accompanied by brain damage or functional loss of lower body muscles on the paretic side1 , 2 . despite the development of modern medicine , economic growth , and widening interests in health , its occurrence is i...
[ purpose ] the purpose of this study was to investigate the effects of an 8-week program of pilates exercise on gait in chronic hemiplegia patients and to determine whether or not it can be used for rehabilitation in postsrtoke patients . [ subjects and methods ] twenty individuals with unilateral chronic hemipa...
many women use natural health products for relief of menopausal symptoms and perceive these products as safe.phytotherapeutic products for menopausal complaints can contain plants with phytoestrogenic properties.the use of phytoestrogens can be related to endometrial hyperplasia and subsequent vaginal hemorrhage . se...
two 54-year - old women developed abdominal cramps and vaginal hemorrhage as a result of endometrial hyperplasia during treatment with a hop - containing phytotherapeutic product ( menocool ) for post - menopausal complaints . the women used the hop - containing phytotherapeutic product ( 418 mg of hop per tablet ) t...
inflammatory bowel disease ( ibd ) , cd , and uc are chronic relapsing inflammatory disorders of the intestine with unknown causes . ibd develops upon the interaction between genetic predisposition leading to immunological abnormalities , environment , and microbiome . none of these factors alone are sufficient to ...
inflammatory bowel disease ( ibd ) is defined as a chronic and relapsing inflammatory disorder of the intestine . intestinal inflammation in ibd has been proposed to be attributable to the interplay between microbial , genetic , environmental , and immunological factors . the incidence and prevalence rates of ibd are...
breast cancer ( bc ) continues to remain the commonest cause of cancer death in women worldwide . bc is increasing in regions that until recently had low rates of the disease . in asia , bc incidence peaks among women in their forties , whereas in the united states and europe , it peaks among women in their 60 's . ...
background : brca1/2 genes mutation prevalence varies among ethnic groups and may be influenced by founder mutations . understanding brca1/2 genes mutations is important for reducing breast cancer ( bc ) incidence , accurate risk assessment and counseling . this systematic review of the literature was conducted to ...
the arterial stiffness is an index of vascular health and has been shown to confer additional independent predictive value for adverse cardiovascular outcomes in patients with uncomplicated essential hypertension as well as in the general population [ 2 , 3 ] . the measurement of carotid to femoral pulse wave veloc...
in medical practice the reference values of arterial stiffness came from multicenter registries obtained in asia , usa , australia and europe . pulse wave velocity ( pwv ) is the gold standard method for arterial stiffness quantification ; however , in south america , there are few population - based studies . in thi...
the human thumb is opposable and prehensile , making it the most unique digit of the hand , responsible for hand functions , grasp , manual dexterity , and fine motor skills . the thenar eminence constitutes the intrinsic muscles of the hand that are responsible for complex movements of the thumb . congenital anoma...
congenital absence of flexor pollicis longus with or without associated anomalies of thenar muscles and thumb is of rare occurrence . inability to flex the interphalangeal joint of the thumb and absent dorsal wrinkles and flexion creases of the thumb are important clues to the diagnosis . routine radiography and cr...
nearly 200 cases of calcifying epithelial odontogenic tumor have been reported in literature since pindborg described it as a separate pathologic entity in 1955 . it has been identified under different denominations , such as , ameloblastoma of unusual type with calcification , calcifying ameloblastoma , malignant od...
calcifying epithelial odontogenic tumor ( ceot ) , also known as pindborg tumor , is a rare benign odontogenic tumor of locally aggressive behavior . it is more common in the posterior part of the mandible of adults , typically in the fourth to fifth decades . its origin as well as its true malignant potential is n...
24-hour abpm plays an important role in determining cardiovascular prognosis and has been shown to be a better predictor of cardiovascular morbidity and mortality as compared to office blood pressure measurements [ 13 ] . the objective was to study the relationship between 24 h abpm and cardiovascular outcomes in pa...
introduction . 24-hour ambulatory blood pressure monitoring ( abpm ) plays an important role in assessing cardiovascular prognosis , through presence or absence of abpm - related prognostic features . objectives . to study relationship between 24-hour abpm and cardiovascular outcomes in patients from chesterfield royal...
acute renal failure ( arf ) is associated with adverse outcomes , especially in children admitted to the pediatric intensive care unit ( picu ) . due to usage of multiple definitions of arf in the literature , causing large variations in the reported incidence and outcome , the term arf was replaced by acute kidney inj...
background : although the term acute renal failure was replaced by acute kidney injury ( aki ) recently , there is a paucity of data on the incidence and profile of aki in critically ill children from the developing world.objectives:the objective of this study is to determine the incidence , etiology , short term outco...
chronic heart failure ( chf ) is the common end - result of many cardiovascular diseases . despite the improvements in the methods of prevention and the new strategies in the treatment of patients , the incidence of chf is increasing in many countries.1 , 2 in recent years , the focus of research for the treatment of c...
backgroundselenium ( se ) is an essential trace element mainly obtained from seafood , meat , and cereals . se deficiency has been identified as a major contributing factor in the pathogenesis of certain congestive heart failure ( chf ) syndromes . since there is controversy over the prevalence of se deficiency among...
it is a significant challenge even to the most experienced anaesthesiologist to intubate patients in whom the movement of the cervical spine is not desirable or restricted . in cases of cervical spine immobility or instability , the use of direct laryngoscopy is reserved : it requires flexion of the cervical spine an...
background : it is difficult to visualise the larynx using conventional laryngoscopy in the presence of cervical spine immobilisation . airtraq provides for easy and successful intubation in the neutral neck position.objective:to evaluate the effectiveness of airtraq in comparison with the mc coy laryngoscope , when pe...
we obtained data on persons with hiv / aids and tb from the national databank at the centers for disease control ( cdc taiwan ) of the department of health , taiwan . coinfection with hiv and tb was defined as hiv infection in persons in whom tb was later diagnosed . a total of 660 persons with both hiv and tb were r...
in 1997 , taiwan made highly active antiretroviral therapy ( haart ) available without cost to hiv - infected persons ; in 2001 , a national web - based surveillance system was implemented . healthcare workers use the system to monitor patients ' conditions and can intervene when necessary . free haart , coupled wi...
small organic molecules with specific interactions with dna have become antitumor , antiviral , and antibiotic drugs [ 1 , 2 ] . duplex dna - binding drugs interact in two main ways , through groove binding and through intercalation . medicinal chemistry has made a considerable effort in searching for and testing o...
the synthesis of oligomers containing two or three acridine units linked through 2-aminoethylglycine using solid - phase methodology is described . subsequent studies on cell viability showed that these compounds are not cytotoxic . binding to several dna structures was studied by competitive dialysis , which showe...
pseudohypoparathyroidism ( php ) was first reported in 1942 by albright who presented 3 cases of hypocalcemia with no response to parathyroid extract and albright hereditary osteodystrophy ( aho ) phenotype of short stature with round facies , obesity , brachydactyly , mental retardation , and subcutaneous calcificatio...
pseudohypoparathyroidism type-1b is a hereditary disorder of clinical hypoparathyroidism without aho phenotype , characterized by blunted nephrogenous cyclic - amp ( camp ) response to exogenous parathyroid hormone ( pth ) . here we report a young adult presenting with hypocalcemic tetany with raised pth levels . h...
a retrocaval ureter or pre - ureteric venacava is a rare anomaly which occurs in 1 per 1000 live births . it is seen three times more often in males and is usually on the right side . a left retrocaval ureter as such is very rare and is usually associated with situs inversus or ivc duplication . these patients us...
retrocaval ureter ( pre - ureteral vena cava ) is an uncommon congenital anomaly that causes ureteral obstruction by external compression . although right retrocaval ureter is a common entity , left retrocaval ureter is extremely rare . a left retrocaval ureter is usually associated with situs inversus or duplicated ...
acute flaccid paralysis ( afp ) is a clinical entity characterized by areflexia and/or hyporeflexia and weakness which reaches a maximum within days or weeks . polioviruses , enterovirus 71 , flavivirus , herpes virus , and rabies virus are well - known as viral etiologic agents . in this article , who presented with...
acute flaccid paralysis ( afp ) is a life - threatening clinical entity characterized by weakness in the whole body muscles often accompanied by respiratory and bulbar paralysis . the most common cause is gullian barre syndrome , but infections , spinal cord diseases , neuromuscular diseases such as myasthenia gravi...
vitamin d status is highly variable among european countries , largely due to variations in exposure to sunshine , dietary intake of vitamin d , and the use of supplements [ 1 , 2 ] . vitamin d can be synthesized endogenously , and factors affecting its cutaneous synthesis include age , season , latitude , time of da...
objective . this paper aims to assess 25(oh)d levels in italian children and adolescents identifying risk factors for 25(oh)d deficiency and to evaluate whether a normal 25(oh)d value can be restored in 25(oh)d - deficient patients . methods . we evaluated 25(oh)d levels in 679 italian children and adolescents ( 10...
the functional asymmetry of the cerebral hemispheres has been reported in patients with many sorts of brain damage , who failed to orient , report , or respond to stimuli located in one hemispace 1 . line bisection has been employed as a sensitive test for unilateral neglect 1,3 . in this task , lateral deviation f...
background and objectives the line bisection error to the left of the true center has been interpreted as a relative right hemisphere activation , which might relate to the subject 's emotional state . considering that patients with generalized anxiety disorder ( gad ) or treatment - resistant depression ( trd ) often ...
uterine leiomyomata , the most common solid pelvic tumors , occur in approximately 20% of women aged 35 years or more . because of the significant operative risk associated with abdominal myomectomy , the operation has been reserved for women who want to preserve or enhance their fertility potential . however , with ...
laparoscopic myomectomy has recently gained wide acceptance . however , this procedure remains technically highly demanding and concerns have been raised regarding the prolonged time of anesthesia , increased blood loss , and possibly a higher risk of postoperative adhesion formation . laparoscopic - assisted myomect...
one of the most frequently asked questions to those of us at june is what kinds of manuscripts are appropriate for inclusion in the journal . any manuscript with the aim of enabling others to enhance their teaching of neuroscience to undergraduates is appropriate ; those with empirically - tested protocols of innovat...
in the fall of 2002 , the faculty for undergraduate neuroscience ( fun ) began publication of its flagship journal , the journal of undergraduate neuroscience education ( june ) . for the past ten years , june has been a major forum for the free exchange of information among undergraduate neuroscience educators . n...
the disease known as pneumocystis carinii pneumonia ( pcp ) is one of the leading causes of illness and death in persons with impaired immunity . the disease has been described in immunocompromised patients for many years , including outbreaks in malnourished young children in orphanages in iran in the 1950s ( 16 ) ....
the disease known as pneumocystis carinii pneumonia ( pcp ) is a major cause of illness and death in persons with impaired immune systems . while the genus pneumocystis has been known to science for nearly a century , understanding of its members remained rudimentary until dna analysis showed its extensive diversity ...
pruritus is an unpleasant feeling that can cause the desire of scratching in a person and can be the symptoms of systemic , infectious , and neurological diseases . causes and treatments of pruritus have been described by traditional persian medicine scientists . the aim of this study was to derive general principles...
background : pruritus is an unpleasant feeling that can cause the desire of scratching in a person and can be the symptoms of systemic , infectious , and neurological diseases . pruritus is the most common clinical manifestation of skin diseases . pruritus prevalence is 8 - 38% in the general population . causes an...
in june 2006 , a 74-year - old woman residing in a house in rural new orleans was bothered by a considerable number ( > 50 ) of insect bites . the woman observed many bugs in the house and showed them to a fumigator , who identified them as triatomines . an internet search showed the potential for transmission of c...
autochthonous transmission of the chagas disease parasite , trypanosoma cruzi , was detected in a patient in rural new orleans , louisiana . the patient had positive test results from 2 serologic tests and hemoculture . fifty - six percent of 18 triatoma sanguisuga collected from the house of the patient were posit...
a 2.5 kb vec promoter sequence was cloned between insulators from the chicken -globin gene 29 and used to drive cre expression . r26r - lacz/+;vec - cre or r26r - yfp/+;vec - cre conceptuses were generated by crossing vec - cre/+ males with r26r - lacz/+ or r26r - yfp/+ females . runx1;vec - cre and runx1;vec - cre...
hscs are the founder cells of the adult hematopoietic system , and thus knowledge of the molecular program directing their generation during development is important for regenerative hematopoietic strategies . runx1 is a pivotal transcription factor required for hsc generation in the vascular regions of the mouse con...
the main study sample included 190 women aged 33 to 68 years recruited through the elective surgery schedule of the gynecology unit at the laval university medical research center , qubec , canada . surgeries were scheduled for total ( n = 184 ) or subtotal ( n = 6 ) abdominal hysterectomies sometimes accompanied by ...
objectivewe assessed whether subcutaneous and omental adipocyte hypertrophy are related to metabolic alterations independent of body composition and fat distribution in women.research design and methodsmean adipocyte diameter of paired subcutaneous and omental adipose tissue samples was obtained in lean to obese women ...
a 20-year - old incarcerated indigenous australian male , with a history of hepatitis c and intravenous drug abuse , was admitted to the intensive care unit with fulminant hepatic failure following a 5-day history of jaundice , nausea , and vomiting . the patient was opioid dependent but had been previously well with...
key clinical messagea 20-year - old indigenous australian male was admitted to the intensive care unit with fulminant hepatic failure secondary to intravenous use of buprenorphine , which had been prescribed sublingually for opioid dependence . intravenous buprenorphine - induced hepatitis is well recognized , howeve...
gemcitabine - induced hemolytic uremic syndrome ( hus ) is rare but can often be fatal . early detection of hus is critical so that contributing chemotherapeutic agents , such as gemcitabine , can be discontinued . in clinical trials , hus is characterized by renal failure , microangiopathic hemolytic anemia ( maha...
hemolytic uremic syndrome ( hus ) is a rare thrombotic complication characterized by a triad of microangiopathic hemolytic anemia , thrombocytopenia , and acute renal failure . hus may be caused by several different conditions , including infection , malignancy , and chemotherapeutic agents , such as mitomycin , cisp...
health related quality of life ( hrqol ) includes not only physical functioning but also emotional and social functioning dimensions . to assess effectiveness of clinical trials , hrqol measuring instruments hrqol instruments assist healthcare services in creating better relationship between patients and their physic...
introduction : to evaluate the reliability , validity and feasibility of the persian version of the pediatric quality of life inventory ( pedsql 4.0 4.0 ) generic core scales in iranian healthy students ages 7 - 15 and chronically ill children ages 2-18.methods:we followed the translation methodology proposed by develo...
the use of female human resources is highlighted as an important factor in the aging korean society , especially as married women have started entering the labour market . in addition , a wide range of fields utilize female labour and the distribution ratio of women in each field is increasing , with female par...
[ purpose ] a scalp massage was conducted on female office workers divided into a 15 minute group and 25 minute group and its effect on stress hormone , blood pressure and heart rate was analyzed in order to provide a theoretical rationale to apply scalp massage as stress therapy . [ subjects and methods ] a sc...
chitin is plentiful in the structural coatings of fungi , insects , and parasitic nematodes , but it is not produced in mammals . chitin , the linear polymer of -1,4 linked -n - acetyl - glucosamine ( glcnac ) , is the most abundant biopolymer in marine ecosystems and , after cellulose , the second most copious polys...
chitinases have an important role in the defense of organisms against chitin - containing parasites . an acidic mammalian chitinase ( amcase ) has been detected in epithelial cells in lung tissue samples taken from patients with asthma as well as in conjunctival epithelium of patients with inflammatory ocular disease...
small cell lung cancer ( sclc ) is highly malignant neoplasm , derived from neuroendocrine cells . it represents approximately 15% of all bronchial carcinomas , and this percentage is tending to decrease recently . in most cases , sclc arises in the larger airways and grows rapidly , becoming quite large . it also ...
abstractsmall cell lung cancer ( sclc ) metastasizes widely , but palatine tonsil is an extremely unusual site for metastasis . idiopathic pulmonary fibrosis ( ipf ) is associated with increased risk of lung cancer . however , the most common histological findings among patients of lung cancer with ipf are known as...
almost all countries , irrespective of economic status , are currently experiencing an obesity epidemic.13 residence area , occupation , and lifestyle significantly modify the body fat composition , and thus affect the prevalence of obesity.4,5 as a country undergoing economic transition , the people s republic of chin...
objectivethe study aimed to investigate the prevalence of overweight , obesity , and cardiometabolic abnormalities , the influence of residence area , occupation , and lifestyle on new anthropometric indices , and the relationship between anthropometric indices and cardiometabolic abnormalities in a chinese community -...
isolated pauci - immune pulmonary capillaritis ( ipipc ) is a rare disorder of unknown etiology . it is characterized by small vessel vasculitis confined to lungs , and systemic manifestations are typically absent . it is considered as a subset of microscopic polyangiitis ( mpa ) but is mostly sero - negative for a...
a young house wife presented with low grade fever , cough , haemoptysis and sob of unknown aetiology for 40 days duration . respiratory system examination revealed diffuse crepts and rhonchi . other organ system examination did not reveal any abnormality . x - ray chest pa view and ct thorax showed diffuse bilate...
when oxygen supply to the fetus is significantly disrupted , tissue oxygenation deprivation develops , acids begin to accumulate and acidemia develops . umbilical cord blood gas measurement in comparison with the fetal scalp ph monitoring could better detect a hypoxic baby . in 1952 , virginia apgar , proposed a scor...
objectivethe apgar score as a proven useful tool for rapid assessment of the neonate is often poorly correlated with other indicators of intrapartum neonatal well - being . this study was carried out to determine the correlation between umbilical cord ph and apgar score in high - risk pregnancies.methodsthis is a pro...
vaccination has been one of the most effective measures to control infectious diseases in the 20th century . most of the viral ( mumps , rubella , measles , varicella and rotavirus ) and bacterial ( tetanus , diphteria , haemophilus influenzae , streptococcus pneumoniae , meningococcus group c ) diseases traditionall...
summaryconventional vaccines have been extremely successful in preventing infections by pathogens expressing relatively conserved antigens through antibodymediated effector mechanisms . thanks to vaccination some diseases have been eradicated and mortality due to infectious diseases has been significantly reduced . h...
suicide is an important health challengeand one of the main leading causes of premature death worldwide ( 1 , 2 ) . suicide rate is among the top three causes of death in people aged 1544 yr old ( 3 ) . the rate of suicide ideation is reported to be highest among elderly ( 1 ) . completed suicide is 5% to 10% of ...
background : we aimed to assess the high - risk group for suicide using different classification methods includinglogistic regression ( lr ) , decision tree ( dt ) , artificial neural network ( ann ) , and support vector machine ( svm).methods : we used the dataset of a study conducted to predict risk factors of comple...
amyotrophic lateral sclerosis ( als ) is a common progressive , neurodegenerative disorder of the voluntary motor system that affects motor neurons in the cerebral cortex , brain stem , and spinal cord . the latter rapidly leads to pulmonary compromise requiring mechanical ventilation and represents the major cause o...
respiratory dysfunction and complications are the most common causes of death in amyotrophic lateral sclerosis . this is a pilot study to observe the changes in respiratory physiology parameters after sa - am acupuncture treatment . eighteen als patients received sa - am acupuncture treatment twice a day for 5 days...
technological advances in industrial societies have led to sedentary lifestyles at home and at work . inactivity and the excess intake of calorie - rich foods are the main culprits in the twin epidemics of obesity and type 2 diabetes - associated cardiovascular disease , disproportionately affecting women , especiall...
obesity disproportionately affects women , especially those of african descent , and is associated with increases in both fat and muscle masses . although increased extremity muscle mass may be compensatory to fat mass load , we propose that elevated insulin levels resulting from diminished insulin sensitivity may addi...
target of rapamycin ( mtor ) is an evolutionarily conserved serine / threonine kinase that regulates cell growth and division in response to energy levels , growth signals , and nutrients . control of mtor activity is critical for the cell since its dysregulation leads to cancer , metabolic disease , and diabetes . i...
lysosomes are key cellular organelles that play a crucial role in catabolism by degrading extracellular and intracellular material . it is , therefore , very intriguing that mtorc1 ( mechanistic target of rapamycin complex 1 ) , a major promoter of anabolic processes , localizes in its active form to the surface of l...
there are several medical and surgical [ 2 , 3 ] treatment options for obstructive sleep apnea ( osa ) . patients who use continuous positive airway pressure ( cpap ) devices have been shown to have nasal obstruction as a common complaint ( estimated prevalence : 2545% ) [ 46 ] . as described by poiseuille 's law...
objective . to evaluate the effect of turbinate sizes on the titrated continuous positive airway pressure ( cpap ) therapeutic treatment pressures for patients with obstructive sleep apnea ( osa ) who have not had nasal surgery . study design . retrospective case series . methods . a chart review was performed fo...
in november 2009 , a bat was found on the ground in bokeloh , lower saxony , germany ( 522513.99n ; 92331.56e ) . it was given mealworms and water ad libitum supplemented with minerals and vitamins . in february 2010 , the bat began to act aggressively , directly approaching any moving object , vigorously trying to b...
a virus isolated from a natterer s bat ( myotis nattererii ) in germany was differentiated from other lyssaviruses on the basis of the reaction pattern of a panel of monoclonal antibodies . phylogenetic analysis supported the assumption that the isolated virus , bokeloh bat lyssavirus , may represent a new member of ...
however , its administration is associated with problems , such as the adjustments needed to maintain an effective blood concentration . in addition , dietary restrictions are necessary , because vitamin k levels influence warfarin s efficacy . in recent years , novel oral anticoagulants ( noacs ) those have ...
objective : oral anticoagulants are widely administered to patients with atrial fibrillation in order to prevent the onset of cardiogenic embolisms . however , intracranial bleeding during anticoagulant therapy often leads to fatal outcomes . accordingly , the use of novel oral anticoagulants ( noacs ) , which le...
many people are not aware of the harmful effects of radiofrequency waves ( rf ) and their role in cancer and other serious risks . scientific evidence suggests that cancer is not only linked to mobile phone radiation and that other factors also may be involved in its development . most mobile operators use from rad...
introductionpublic and occupational exposure to electromagnetic fields due to the growing trend of electronic devices may cause adverse effects on human health . this paper describes the risk of mutation and sexual trauma and infertility in masculine sexual cell by mobile phone radiations.methodsin this study , we meas...
the transforming growth factor - beta ( tgf ) was discovered more than two decades ago and was isolated as a secreted factor from sarcoma virus - infected cells [ 13 ] . tgf was shown to transiently confer on normal fibroblasts phenotypic properties of transformed cells , as demonstrated by their acquired ability to ...
the transforming growth factor - beta ( tgf ) superfamily encompasses widespread and evolutionarily conserved polypeptide growth factors that regulate and orchestrate growth and differentiation in all cell types and tissues . while they regulate asymmetric cell division and cell fate determination during early develo...
intersphincteric resection ( isr ) is a procedure that aims to preserve anal function in patients with very low rectal cancer . since the introduction of laparoscopic rectal surgery for rectal cancer first described laparoscopic isr ( lap isr ) in 2000 , and a number of cases have since been reported . we present o...
intersphincteric resection ( isr ) is a procedure designed to preserve anal function in cases with very low rectal cancer . we report our clinical experience with laparoscopic isr ( lap isr ) performed using needlescopic instruments . first , a camera port is created at the umbilicus . two 5-mm ports are then ins...
it is well known that the main phenomenon of hypoxemia in acute lung injury / acute respiratory distress syndrome ( ali / ards ) is the high shunt fraction caused by the nonaerated areas of the lungs . during the disease process , the volume of extravascular lung water and the lung weight increase and promote the col...
recruitment maneuvers and positive end - expiratory pressure ( peep)/tidal ventilation titration in acute lung injury / acute respiratory distress syndrome ( ali / ards ) are the cornerstone of mechanical ventilatory support . the net result of these possible adjustments in ventilatory parameters is the interaction o...
fast quantum - chemical methods are indispensable for computationally demanding calculations of electronic properties of large molecules . in the 1970s and 1980s , semiempirical quantum - chemical ( sqc ) methods were the workhorse in computational studies of ground - state properties . since the 1990s , they...
the semiempirical orthogonalization - corrected omx methods ( om1 , om2 , and om3 ) go beyond the standard mndo model by including additional interactions in the electronic structure calculation . when augmented with empirical dispersion corrections , the resulting omx - dn approaches offer a fast and robus...
electroconvulsive therapy ( ect ) is one of the most efficacious treatment of major depressive disorder ( mdd ) . it is used as a rapid and efficacious treatment in emergent and/or treatment resistant forms of other psychiatric disorders . the cognitive aspects which are influenced immediately after ect are : orien...
background : electroconvulsive therapy ( ect ) is one of the most efficacious treatment for major depressive disorder ( mdd ) , it is also used as a rapid and efficacious treatment for other psychiatric disorders , especially treatment resistant ones . the cognitive impairment is one of the most important side effect...
the off - season period ( i.e. transition period ) has taken a relevant role across the soccer s world . considering the growing economic importance of soccer competitions and the increase of the number of matches around the world ( regardless of the competitive - level ) , soccer referees have been involved in offic...
abstractthe evolution of referees physical fitness has been studied over one or several seasons , however , the variation of the physical performance between the end of the competitive season ( t1 ) and the start of the following pre - season ( t2 ) has not been ascertained . therefore , the aim of this study was to ...
prevalence and risk of overweight were assessed in 232 children who were enrolled in the prospective german gdm offspring study between 1989 and 2000 . all children were from singleton births , had a mother with gdm diagnosed according to criteria of the german diabetes association using an oral glucose tolerance tes...
objectivegestational diabetes mellitus ( gdm ) is associated with high birth weight in the offspring . this may lead to overweight and insulin resistance during childhood . the aim of the study was to assess the impact of gdm on overweight risk and insulin resistance in offspring.research design and methodsbmi meas...
talc pleurodesis ( tp ) is a procedure first described by bethune 1 in 1935 as a means to anchor the lung during lobectomy 2 . ever since then , tp has been employed worldwide in the management of recurrent pneumothorax and malignant pleural effusion , with a success rate in excess of 90% 3 - 5 . tp is performed by i...
purpose : talc pleurodesis ( tp ) is employed worldwide for the management of persistent pneumothorax or pleural effusion , particularly of malignant origin . however , there are very little available data on 18f - fluorodeoxyglucose positron - emission tomography / computed tomography ( 18f fdg pet / ct ) response eva...
the united states department of defense and department of veteran affairs are dedicated to providing superior rehabilitation care for veterans and service members who have suffered combat - associated traumatic limb loss . current literature reports that 70% of amputees with multiple limb loss are bothered by sweatin...
hyperhidrosis - related to prosthesis use in patients who have suffered a traumatic limb amputation presents itself as a barrier to comfort , prosthesis use and overall quality of life . this review intends to encourage dermatologists to consider the use of botulinum toxin a or b for the treatment of hyperhidrosis in...