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malnutrition is present in 1855% of hospitalized patients ( sorensen et al . , 2008 ; imoberdorf et al . , studies show that nutritional support to undernourished patients and those at nutritional risk is advantageous ( stratton and elia , 2007 ) . european guidelines state that provision of tailored food should be...
background / objectives : malnutrition is present in 2050% of hospitalized patients , and nutritional care is a challenge . the aim was to evaluate whether the implementation of a nutritional strategy would influence nutritional care performance in a university hospital.subjects/methods:this was a prospective quality i...
eosinophilic enteritis is an uncommon disease of unknown etiology , which can affect any area of the gastrointestinal tract , from the esophagus to the rectum , although the stomach and small bowel are most commonly involved1 ) . it usually presents as colicky abdominal pain , and rarely as an acute intestinal obstru...
eosinophilic enteritis is a rare disease characterized by tissue eosinophilia , which can affect different layers of bowel wall . normally , the disease presents as colicky abdominal pain , and rarely as an acute intestinal obstruction or perforation . in this paper , we report a case of eosinophilic enteritis , hi...
a total of 850 specimens collected from 306 patients who had encephalitis included 306 csf specimens , 304 blood samples , 120 throat swabs , and 120 rectal swabs . all samples were stored at 20c before being transported for analysis and thereafter were stored at 70c at the national institute of virology in pune , in...
an outbreak of viral encephalitis occurred in northern india in 2006 . attempts to identify an etiologic agent in cerebrospinal fluid by using reverse transcription pcr showed positivity to enterovirus ( ev ) in 66 ( 21.6% ) of 306 patients . sequencing and phylogenetic analyses of pcr products from 59 ( 89.3% ) of...
obstructive sleep apnea syndrome ( osas ) is a condition of sleep - disordered breathing , which is characterized by the repetitive complete or partial collapses of the pharyngeal airway during sleep . it has been known to frequently involve middle - aged people and to be found in 2% of women and 4% of men ( 1 ) . ...
the risk of cardiovascular disease is known to be increased in obstructive sleep apnea syndrome ( osas ) . its mechanism can be explained by the observation that the sympathetic tone increases due to repetitive apneas accompanied by hypoxias and arousals during sleep . heart rate variability ( hrv ) representing ca...
relying on previous spatial analysis of bu incidence in akonolinga district , we analyzed a series of cases that occurred in the highest bu - risk area of the district , located along the nyong river upstream of akonolinga ( 3 ) . we analyzed 562 new cases of bu that originated in this area from january 2002 through ...
to determine when risk for buruli ulcer is highest , we examined seasonal patterns in a highly disease - endemic area of cameroon during 20022012 . cases peaked in march , suggesting that risk is highest during the high rainy season . during and after this season , populations should increase protective behaviors ,...
molybdenum participates in several enzyme reactions including xanthine oxidase , aldehyde oxidase and sulfite oxidase . the molybdenum cofactor ( moco ) is essential for the activity of these enzymes and is associated with amidoxime reductase in mitochondria . moco deficiency ( mocd ) causes a severe progressive me...
backgroundmolybdenum cofactor deficiency ( mocd ) is a severe autosomal recessive neonatal metabolic disease that causes seizures and death or severe brain damage . symptoms , signs and cerebral images can resemble those attributed to intrapartum hypoxia . in humans , molybdenum cofactor ( moco ) has been found to ...
many authors have discussed the importance of measuring cardiac output and then titrating therapy according to these measurements in patients in the operating theatre and intensive care environments . indeed , in some circumstances these measurements have led to changes in therapy that , in themselves , have been ass...
pulse pressure analysis algorithms are commonly used to measure cardiac output and to allow for the rational titration of therapy in critically ill patients . the ability of these algorithms to accurately track changes in stroke volume ( and cardiac output ) is thus very important . most of the currently available ...
social value orientation characterizes individual differences in anchoring attitudes towards the division of resources . here , by contrasting people with prosocial and individualistic orientations using functional magnetic resonance imaging , we demonstrate that degree of inequity aversion in prosocials is predicta...
viral hepatitis due to hepatitis b virus ( hbv ) is a major worldwide public health concern leading to acute and chronic liver disease including cirrhosis and hepatocellular carcinoma ( hcc ) ( 14 ) . it is currently estimated that over 2.5 billion people are exposed and over 350 million people are chronically infect...
hepseq is a repository for an extensive library of public health and molecular data relating to hepatitis b virus ( hbv ) infection collected from international sources . it is hosted by the centre for infections , health protection agency ( hpa ) , england , united kingdom . this repository has been developed as a...
stress is described as any combination of environmental conditions ( such as temperature , relative humidity , immobility , and solar radiation ) that will cause the temperature of the environment to be higher than the temperature range of the animal s temperature zone / thermal neutral zone . temperatures above the ...
introductionpeppermint is an efficient medicinal plant for the treatment of diseases , and it also can be used to produce raw materials in the pharmaceutical industry . the purpose of the current study was to evaluate the effects of various levels of peppermint alcoholic extract on body - weight gain and blood bioche...
the major clinical symptoms of migraine include moderate - to - severe pulsatile headaches , often accompanied by nausea and vomiting . optical and acoustic stimuli , as well as some daily activities , are known to exacerbate migraine headaches , whereas a quiet environment and plenty of rest can relieve the headache...
backgroundmigraine is a chronic disease that interferes with life quality and work productivity . valproate shows protective effects against migraine , yet the underlying mechanisms are unclear . this study aimed to evaluate the potential effect of valproate on migraine using a rat model of nitroglycerin - induced tr...
as korea also experiences the graying of society , awareness of prostate cancer has increased , and with the introduction of prostate - specific antigen ( psa ) , prostate cancer can be detected and treated early . the sensitivity of psa to detect prostate cancer has been reported to be high . recently , as its mea...
purposetransrectal ultrasound - guided prostate biopsy is the procedure of choice for diagnosing prostate cancer . we compared with pain - relieving effect of acetaminophen , a known drug for enhancing the pain - relieving effect of tramadol , and eutectic mixture of local anesthetics ( emla ) , a local anesthetic ag...
approved study included consecutive patients who underwent ventral hernia repair with components separation with padm reinforcement performed by the author at the university of pittsburgh medical center ( pittsburgh , pennsylvania ) and butler memorial hospital ( butler , pennsylvania ) . surgeries were performed bet...
repair of complex ventral hernias frequently results in postoperative complications . this study assessed postoperative outcomes in a consecutive cohort of patients with ventral hernias who underwent herniorrhaphy using components separation techniques and reinforcement with non cross - linked intact porcine - deriv...
alzheimer s disease ( ad ) is the most common cause of senile dementia.1 it was first described by alois alzheimer in 1906.2 in 2012 , there were 36 million people worldwide with ad . it is predicted to affect more than 115 million people globally by 2050.3 it is a progressive , neurodegenerative disorder that is usu...
backgrounddonepezil is an acetylcholinesterase inhibitor indicated for alzheimer s disease . the aim of this randomized , single - blind , placebo - controlled , single - dose , dose - escalation study was to investigate the safety , tolerability , and pharmacokinetics of the donepezil patch in healthy male subjects....
dendritic cells ( dc ) are a subpopulation of leukocytes specialized in the capture and process of antigens and its presentation to t lymphocytes . in their immature state , they are located in peripheral tissues acting as sentinels . tissue residing dc form a close network , optimally positioned to sense invading pa...
dendritic cells ( dc ) play an important role in the development and maintenance of immune tolerance . although the inhibitory receptor ilt4/lilrb2 has been related with the tolerogenic phenotype of dc , the possible role of this receptor in the breakdown of dc tolerogenic function in systemic lupus erythematosus ( s...
the oral anticoagulant therapy ( oat ) , used to prevent thrombosis , is associated with substantial avoidable hospitalization . identify the associations between chronic care management and the quality of oat as suggested by the chronic care model ( ccm ) of wagner . regression analysis with data of 61 thrombosis ...
introductionthe oral anticoagulant therapy ( oat ) , used to prevent thrombosis , is associated with substantial avoidable hospitalization.aimidentify the associations between chronic care management and the quality of oat as suggested by the chronic care model ( ccm ) of wagner.methodsregression analysis with data of ...
a recent genome - wide association study ( gwas ) found a sequence variant in dab2ip ( rs7025486[a ] ) to be strongly associated with the presence of abdominal aortic aneurysm ( aaa ) with a per - allele odds ratio ( or ) of 1.21 ( p= 4.6 10 ) . the authors also found an association with early - onset myocardial inf...
aimsa sequence variant , rs7025486[a ] , in dab2ip on chromosome 9q33 has recently been associated with coronary heart disease ( chd ) . we sought to replicate this finding and to investigate associations with a panel of inflammatory and haemostatic biomarkers . we also sought to examine whether this variant , in c...
ferromagnetic nanostructures are an important part in basic research but also in nanotechnological applications like magneto - optical devices , high density data storage , and also in biomedicine such structures at the nanoscale are promising candidates for example in drug delivery , imaging or targeting of special ce...
a magnetic semiconductor / metal nanocomposite with a nanostructured silicon wafer as base material and incorporated metallic nanostructures ( ni , co , nico ) is fabricated in two electrochemical steps . first , the silicon template is anodized in an hf - electrolyte to obtain a porous structure with oriented pores ...
gastroesophageal reflux disease ( gerd ) broadly includes the whole spectrum of reflux disease , from intermittent symptoms like heartburn or acid regurgitation to endoscopic reflux esophagitis and barrett 's esophagus.1 it usually gives a considerable impact on the quality of the patient 's life not only by the sympto...
ethnic and geographical differences are important factors in studying disease frequencies , because they may highlight the environmental or genetic influences in the etiology . we retrieved the studies which have been published regarding the epidemiologic features of gastroesophageal reflux disease ( gerd ) in asia ,...
adverse drug reaction ( adr ) is defined as a response to a medicine , which is noxious , unwanted or harmful , and unintended , and which occurs at doses normally used in human for the prophylaxis , diagnosis or therapy of disease , or for the modification of physiological function.1 incidences of adverse reactions to...
background : documentation of adverse drug reactions ( adrs ) is critical to a safe health delivery system . the aim of our study was to explore the prevalence of self - reported sulphonamide hypersensitivity reactions in a community - based sample of the general population in ibadan , nigeria . we also examined soci...
bacterial pathogens predominantly respond to environmental changes , such as entry into a host , by adapting their physiology through altered gene expression . the gene products that give a pathogen an enhanced chance of survival within the host are termed virulence factors . pathogens use a variety of different me...
it is widely acknowledged that rna stability plays critical roles in bacterial adaptation and survival in different environments like those encountered when bacteria infect a host . bacterial ribonucleases acting alone or in concert with regulatory rnas or rna binding proteins are the mediators of the regulatory outc...
in china , maize ( zea mays l. ) is the most important cereal crop , and the production of this crop is affected by soil salinity . thus , many salinity - tolerant crops , such as maize and rice , have been developed using transgenic technology . researchers have found that the microbial communities in the rhizosph...
maize ( zea mays l. ) is the most important cereal crop in the world . however , soil salinity has become a major problem affecting plant productivity due to arable field degradation . thus , transgenic maize transformed with a salinity tolerance gene has been developed to further evaluate its salt tolerance and ef...
a 28-year - old male patient came to our hospital outpatient department with complaints of short hair ( 5 - 8 mm in length ) coming out from the left upper eyelid since childhood as reported by his parents . on close examination by the dermatologist and the physician , the ectopia cilia was located 7 mm superior -...
we present a case of ectopia cilia in a 28-year - old male patient . ectopia cilia was were seen in the outer third of left upper eyelid . the patient 's maternal grandfather also had ectopia cilia of the left upper eyelid as reported by the patient 's mother . ectopia cilia is a rare condition seen in humans . ...
the different forms of acute myeloid leukemias ( amls ) * are characterized by the arrest of cell differentiation , the induction of cell proliferation , and the repression of normal hematopoiesis . these malignancies are often associated with recurrent chromosomal translocations , most of which encode fusion protein...
differentiation therapy for acute myeloid leukemia uses transcriptional modulators to reprogram cancer cells . the most relevant clinical example is acute promyelocytic leukemia ( apl ) , which responds dramatically to either retinoic acid ( ra ) or arsenic trioxide ( as2o3 ) . in many myeloid leukemia cell lines , c...
transrectal ultrasound guided prostate biopsy ( trus - bx ) is a standard procedure used for prostate cancer detection . however , it has recently been reported that most of the patients that undergo trus - bx tolerated the associated discomfort , and 20% of these patients experienced severe pain [ 1 - 3 ] . theref...
purposeprostate biopsy for diagnosing cancer can be painful . the efficacy and safety of combination perianal - intrarectal lidocaine - prilocaine ( pilp ) cream and periprostatic nerve block were compared with nerve block alone during transrectal ultrasound guided prostate biopsy ( trus - bx).materials and methodsfr...
renal cell carcinoma ( rcc ) is the seventh and eighth most common cancer in men and women respectively . although prevalent utilization of cross - sectional imaging allowed early detection of asymptomatic renal tumors , a significant number of patients present with large and metastatic rcc . the prognosis of metas...
we describe the case of a patient with a large renal cell carcinoma ( rcc ) who underwent cytoreductive nephrectomy utilizing liver mobilization techniques similar to those used in transplantation . despite recurrent metastases , our patient continues to survive eight years later with several metastasectomies and adj...
end stage renal disease ( esrd ) is a serious health problem among children , especially among children aged < 2 years . it has particular features in terms of etiology and therapeutic modalities . the management of infants with esrd aims , on the one hand , at increasing patients longevity and , on the other hand , ...
end stage renal disease ( esrd ) in infants has particular features in terms of etiologies and therapeutic modalities . the aim of our study is to describe the etiologies and the esrd outcomes among tunisian infants . this retrospective study was conducted over 15 years ( from january 1998 to december 31 , 2013 ) i...
the ebola haemorrhagic fever ( ebola hf ) also known as ebola virus disease ( evd ) , is an acute viral haemorrhagic illness caused by filoviridae family.1 ebola viral fever , a highly contagious haemorrhagic disease has today become a major public health concern in the developing countries worldwide . since 1976 , the...
background : ebola viral fever , a highly contagious haemorrhagic disease has today become a major public health concern in the developing countries worldwide.aim:the purpose of this study was to assess knowledge among dental practitioners regarding ebola haemorrhagic fever ( ebola hf ) in tricity , ( chandigarh , panc...
diabetic ketoacidosis ( dka ) is an acute complication of diabetes mellitus and is characterized by excessive production of betahydroxybutyric and acetoacetic acids leading to low blood ph . an arterial ph of less than 7.3 is required in order to diagnose dka . rarely , because of other complicating factors , blood...
diabetic ketoacidosis ( dka ) is characterized by excessive production of organic acids leading to a low blood ph . rarely , because of other complicating factors blood ph may be in the alkalemic range and the term diabetic ketoalkalosis has been coined to describe this condition . so far , less than 30 such cases ha...
although the development of efficient antiretroviral treatment options has changed the face of the aids epidemic in industrialized countries , opportunistic infections like toxoplasmic encephalitis or pneumocystis pneumonia still present a considerable challenge [ 1 - 3 ] . especially in patients in a late stage of hiv...
objectivesthere is only little data on immune reconstitution in antiretroviral nave aids - patients with toxoplasmosis . the observation of several cases with reduced increase of cd4-cells upon start of antiretroviral treatment ( art ) prompted us to investigate the topic using the clinsurv cohort.methods17 german hi...
the cardia study is a multicenter , longitudinal investigation of the evolution of ischemic heart disease risk starting in young adulthood ( 17 ) . the study began in 19851986 with 5,115 black and white adults 1830 years of age from four metropolitan areas ( birmingham , al ; chicago , il ; minneapolis , mn ; and oak...
objectivethe relation of breakfast intake frequency to metabolic health is not well studied . the aim of this study was to examine breakfast intake frequency with incidence of metabolic conditions.research design and methodswe performed an analysis of 3,598 participants from the community - based coronary artery risk...
qt was received as gifted by torrent pharmaceuticals pvt . ltd . , polyox n 10 , polyox n 80 , polyox n 750 and polyox n 205 were gifted by dow chemicals pvt preliminary trials were carried out for selection of appropriate grades of polyox from different grades mentioned above . concentration of polymer and plastic...
quick dissolving film prepared by various grades of polyox like polyox n10 , n80 , n750 and n205 . polyox having excellent film forming capacity with rapid hydration power which leads to rapid disintegration of film upon contact with saliva . film is optimized for concentration of polymer and plasticizer using ccd ...
duplication of the alimentary tract is an important surgical condition , which includes a wide variety of mass lesions . we encountered a patient who presented with perforation of the duplication , which was associated with malrotation with midgut volvulus . being an extremely uncommon surgical emergency , it is be...
duplication of the alimentary tract is an important surgical condition . it may occur anywhere in the gastrointestinal tract . an important complication of this entity is perforation of the normal or abnormal gut . malrotation with midgut volvulus can be a surgical emergency . we present a patient , who present...
the nmr structure of budding yeast chaperone chz1 complexed with histones h2a.z - h2b has been determined . chz1 forms a long irregular chain capped by two short -helices , and uses both positively and negatively charged residues to stabilize the histone dimer . a molecular model that docks chz1 onto the nucleosome h...
historically the problem of visual stability has been simplified to address only a fixed visual world with a fixed head . until a few decades ago the dominant theory evoked a signal emanating from motor areas of the brain to inform the visual system about eye movements . at the time of an eye movement this signal wou...
space constancy , the appearance of a stable visual world despite shifts of all visual input with each eye movement , has been explained historically with a compensatory signal ( efference copy or corollary discharge ) that subtracts the eye movement signal from the retinal image shift accompanying each eye movement . ...
endovascular embolization has become a method of choice for the treatment of intracranial aneurysms in many centers . however , an important disadvantage of aneurysm coiling is the observed significant rate of recanalization that occurs on average in 20% of patients . therefore , follow - up imaging of coiled aneurys...
summarybackgroundthe use of contrast media and the time - resolved imaging of contrast kinetics ( tricks ) technique have some theoretical advantages over time - of - flight magnetic resonance angiography ( tof - mra ) in the follow - up of intracranial aneurysms after endovascular treatment . we prospectively compar...
facial onset sensory and motor neuronopathy ( fosmn ) is a slowly progressive disorder characterised by facial sensory deficits which may spread to affect the neck , the upper trunk and the limbs , with the development later in the course of the disease of bulbar symptoms such as dysarthria and dysphagia , muscle weakn...
three patients with the clinical and investigation features of facial onset sensory and motor neuronopathy ( fosmn ) syndrome are presented , one of whom came to a post - mortem examination . this showed tdp-43-positive inclusions in the bulbar and spinal motor neurones as well as in the trigeminal nerve nuclei , con...
a 49-year - old man with a history of sick sinus syndrome presented with quadriplegia and ophthalmoplegia . brain magnetic resonance imaging ( mri ) and an angiography examination , which were performed a day after quadriplegia , revealed acute brain infarction in the bilateral midbrain , right median thalamus , and ...
delayed - onset continuous bruxism due to brain stem infarction has not yet been reported . a 49-year old man presented with quadriplegia and ophthalmoplegia . brain mri showed acute infarction in the bilateral midbrain , right thalamus and the superior cerebellum . one month later , the patient developed bruxism w...
although surgery is recommended for ptc , there is no consensus on the therapy when a thyroidectomy is contraindicated because of systemic disease such as heart failure or chronic obstructive pulmonary disease . hypertrophic cardiomyopathy is a common genetic cardiovascular disease with a high risk of sudden death an...
standard therapy has not been established for thyroid cancer when a thyroidectomy is contraindicated due to systemic disease . herein , we reported a patient who had hypertrophic cardiomyopathy and papillary thyroid carcinoma treated by radiofrequency ablation because of inability to tolerate a thyroidectomy . radiof...
non - gestational choriocarcinomas are rarely seen outside the gonads , with the mediastinum being the main site for these non - gestational extragonadal choriocarcinomas . there is no consensus regarding the use of systemic chemotherapy [ 1 , 2 ] . studies undertaken on treatment for the metastatic disease indicat...
gastric choriocarcinoma is a rare neoplasm and usually accompanies gastric adenocarcinoma . the prognosis is poor due to the aggressive course of the disease . a 57-year - old female patient with weight loss and abdominal pain was examined . the patient was operated following the examination , and pathological an...
nonalcoholic fatty liver disease ( nafld ) is the terminology used for a wide spectrum of disorders ranging from simple steatosis to progressive nonalcoholic steatohepatitis ( nash ) , hepatic fibrosis and cirrhosis and its diagnosis in clinics is based on ultrasonography ( 1 , 2 ) . although , the actual prevalence of...
background : nonalcoholic fatty liver disease ( nafld ) has different prevalence rates in various parts of the world and is a risk factor for diabetes and cardiovascular disease that could progress to nonalcoholic steatohepatitis , cirrhosis , and liver failure.objectives:the current study aimed to investigate the effe...
a previously healthy 19-year - old woman from alberta , canada , returned from australia with increasing fatigue , fever , lethargy , and confusion . she had spent 6 months in new zealand as part of an agricultural exchange , in which her activities included hay bundling , heavy machinery operation , and manure manag...
murray valley encephalitis virus ( mvev ) , a flavivirus belonging to the japanese encephalitis serogroup , can cause severe clinical manifestations in humans . we report a fatal case of mvev infection in a young woman who returned from australia to canada . the differential diagnosis for travel - associated enceph...
glaucoma is an optic neuropathy usually associated with increased intraocular pressure ( iop ) that causes progressive visual field loss . this disease is one of the main causes of blindness worldwide.1 although several risk factors are associated with glaucoma onset and progression , the presence of high levels of i...
travoprost is a prostaglandin analog used in the management of glaucoma and ocular hypertension for reducing intraocular pressure ( iop ) . the iop - lowering efficacy of travoprost has been shown to be similar to that of other prostaglandins , including latanoprost and bimatoprost . when compared with fixed combin...
a venous ulcer is a break in the continuity of the skin resulting from venous hypertension ( figure 1 ) . this is the most common cause of leg ulceration in the united kingdom with a prevalence of 1.53 per 1000 , increasing to 20 per 1000 in patients over 80 years old . this presents significant disease burden to...
objective . to compare the efficacy and cost - effectiveness of simple nonadherent dressings with other more expensive dressing types in the treatment of venous leg ulcers . study design . retrospective cohort study . location . the leg ulcer clinic at the university hospital of south manchester . subjects and ...
the primary goal of periodontal treatment is the maintenance of the natural dentition in health and comfortable function . when periodontal disease has caused a loss of the attachment apparatus , optimal care seeks to regenerate the periodontium to its predisease state . complete and predictable restoration of the ...
the whale 's tail technique performed to obtain maximum interdental papilla fill in the anterior region after placement of bone grafts . this study aims to assess the clinical efficacy of this new technique . this report describes a series of three cases with a probing depth of 67 mm in the maxillary anterior teeth a...
ship ballast ( water ) is a well - recognized conveyer of nonindigenous species [ 15 ] . in an effort to control movements and introductions of nonindigenous species via ballast , the regulation d2 requirement to treat or decontaminate ballast water was developed from international legislation developed by the intern...
ship ballast water is a recognized medium for transfer and introductions of nonindigenous species . there is a need for new ballast water treatment methods that effectively and safely eliminate or greatly minimize movements of these species . the present study employed laboratory methods to evaluate the bactericida...
mature cystic teratoma , the most common type of ovarian teratoma , is also the most common ovarian germ cell - derived neoplasm and it account for 20% of all ovarian tumors 1 . endometriosis coexisting with mature cystic teratoma in the same ovary is extremely rare , although both benign conditions are said to be co...
key clinical messagea coexistence of endometriosis and mature cystic teratoma in the same ovary is a rare occurrence although such tumors of ovaries are said to be common in the reproductive age group . we report a case of fimbrial ectopic pregnancy combined with simultaneous ipsilateral ovarian presentation of endom...
denmark s national health service provides free and equal access to health care for the entire population . health services related events are recorded in national databases , including the danish hospital register and the danish prescription database . information from both registries can be linked to each other ...
objectiveinsulin contributes to normal brain function . previous studies have suggested associations between midlife diabetes and neurodegenerative diseases , including parkinson s disease . using danish population registers , we investigated whether a history of diabetes or the use of antidiabetes drugs was associ...
due to environmental changes , the global incidence of tick - borne disease is increasing worldwide , thus tick - borne diseases have been listed alongside diseases with high emergence risk . several tick - borne pathogens have already emerged in certain geographical regions , such as tick - borne encephalitis virus ...
ticks transmit more pathogens including bacteria , parasites and viruses than any other arthropod vector . although the epidemiological status of many tick - borne bacteria is very well characterized , tick - borne viruses are still relatively under - studied . recently , several novel tick - borne viruses have b...
a passive surveillance system of encephalitis in equine and avian species was set up to detect any occurrence of clinical signs of wnv infection . at the same time , a serologic investigation for wnv was conducted in guadeloupe archipelago . a cross - sectional study was performed on the most susceptible animal spe...
to determine whether west nile virus ( wnv ) had reached the archipelago of guadeloupe , a serologic study in horses and birds was conducted in 2002 . immunoglobulin ( ig ) g , igm , enzyme - linked immunosorbent assay , and seroneutralization tests identified wnv infection in horses and chickens . six months later...
between 2003 and 2006 , 44 patients with ifnfs were diagnosed and treated with mp at an institution . among the 44 patients , 10 who were followed for < 2 years there were 7 men and 27 women with a mean age of 65.5 years ( range , 28 to 86.8 years ) , and all patients were followed for an average of 3.4 years ( range...
backgroundwe evaluated the clinical and radiologic results of impacted femoral neck fractures treated with multiple pinning and determined the influence of the progression of impaction at the fracture site on clinical outcome.methodsthere were 34 patients with a mean age of 65.5 years . the mean follow - up period wa...
cancer is primarily characterized by the uncontrolled proliferation of cells and their ability to metastasize . in spite of significant advances in the fight against cancer , it remains a challenging medical problem . however , toxicity is a major side effect , which limits the utility and effectiveness of such nonta...
backgrounda multifunctional telodendrimer - based micelle system was characterized for delivery of imaging and chemotherapy agents to mouse tumor xenografts . previous optical imaging studies demonstrated qualitatively that these classes of nanoparticles , called nanomicelles , preferentially accumulate at tumor site...
g - protein coupled receptors ( gpcrs ) represent one of the most important classes of drug targets for pharmaceutical industry and play important roles in cellular signal transduction as cell surface receptor proteins 1 . , 2 .. a gpcr only has a single polypeptide that consists of seven transmembrane -helices , thr...
g - protein coupled receptors ( gpcrs ) represent one of the most important classes of drug targets for pharmaceutical industry and play important roles in cellular signal transduction . predicting the coupling specificity of gpcrs to g - proteins is vital for further understanding the mechanism of signal transductio...
neuroblastoma , the most common extracranial solid pediatric malignancy , is an embryonal tumor of the sympathetic nervous system . along with rhabdomyosarcoma , ewing sarcoma and lymphoma , these malignancies collectively represent the small , round blue cell tumors of childhood . in the united states the incidenc...
abstractneuroblastoma is the most common extracranial solid malignancy in children . the tumor has variable biological behavior that can be predicted by patient age , genetic features , tumor biology and extent of disease at diagnosis . factors chosen by various cooperative groups to define risk of treatment failur...
research into the synthesis of noble metal nanoparticles is motivated by the opportunity to harness advantages not present in their bulk equivalents , such as high surface atom to volume ratios , semiconductor properties , and , in some cases , magnetic properties . however , nanosized ir particles have receive...
the synthesis of stable and isolable iridium nanoparticles with an average core size of 1.2 0.3 nm was achieved by employing sodium s - dodecylthiosulfate as a ligand precursor during the modified brust schiffrin reaction . transmission electron microscopy ( tem ) of the isolated ir nanoparticles revealed ...
therapeutic laparoscopy was incorporated into the practice of general surgery more than 25 years ago . since that time , several modifications to minimally invasive access and surgery have been developed with the purpose of further minimizing surgical trauma and improving results : minilaparoscopy , computer - assist...
background and objectives : therapeutic laparoscopy was incorporated into surgical practice more than 25 y ago . several modifications have since been developed to further minimize surgical trauma and improve results . minilaparoscopy , performed with 2- to 3-mm instruments was introduced in the mid 1990s but faile...
artificial oxygen carriers aim at improving oxygen transport and oxygen unloading to the tissue . artificial oxygen carriers may thus be used as an alternative to allogeneic blood transfusions or to improve tissue oxygenation and function of organs with marginal oxygen supply . the present artic...
perfluorocarbon emulsions are being clinically evaluated as artificial oxygen carriers to reduce allogeneic blood transfusions or to improve tissue oxygenation . perfluorocarbon emulsions are efficacious in animal experiments , and in humans they are well tolerated and at least as successful to re...
the skin is continuously exposed to a wide variety of chemical and physical insults and other environmental factors , and therefore , is prone to neoplastic proliferation . in dogs , approximately 30% of all neoplasms the incidence of cutaneous tumors in dogs is estimated to be 728 cases every year per 100,000 dogs ....
over the 42 month period from january 2003 to june 2006 , a total of 2,952 canine biopsy specimens were received from the veterinary medical teaching hospital of seoul national university and from veterinary practitioners across the nation . out of these , 748 ( 25.34% ) cases were diagnosed as canine cutaneous tumor...
totally subcutaneous intravascular portals ( port - a - cath ) are frequently used to administer chemotherapeutic agents . we present a case of port - a - cath fracture with distal embolization causing non - sustained ventricular tachycardia and its percutaneous retrieval . a 68-year old male with diabetes , hypert...
we describe the case of a patient with a previously placed port - a - cath who was admitted to hospital for new onset of non - flushing catheter and palpitations with ventricular tachycardia . a chest x - ray and a linogram showed a port - a - cath fracture and distal embolization into the right ventricle resulting i...
apocrine carcinoma , also known as apocrine - gland carcinoma and sweat - gland carcinoma comprises of a group of extremely rare , malignant tumor , which shows features of apocrine differentiation . the disease is primarily diagnosed in the fifth to seventh decade of life , with similar incidence in men and women an...
apocrine carcinoma ( ac ) is a rare tumor with heterogeneous presentation . the disease has a highly morbid course and little is known about it . we present an otherwise healthy , 62-year - old asian male who originally presented with chronic swelling of his left eyelid associated with excessive tears and diminishe...
the emergency department may offer a window of opportunity for women to discuss their experiences of intimate partner violence ( ipv ) with nurses and other health care providers . exposure to ipv impacts women 's health leading to acute and long - term physical and mental impairment [ 14 ] . lifetime prevalence ...
background . the transtheoretical model of change ( ttm ) was used as a framework to examine the steps that women took to disclose intimate partner violence ( ipv ) in urban emergency departments . methods . mapping methods portrayed the evolving nature of decisions that facilitated or inhibited disclosure . this...
it is characterized by tubular crystalline deposits of calcium oxalate leading to acute and chronic tubular injury , interstitial fibrosis , and progressive renal insufficiency . a 54-year - old male was seen in our nephrology clinic for progressive increase in his serum creatinine from 1.38 to 3.66 mg / dl over 9 mo...
obesity is a major public health issue all over the world . bariatric surgery is increasingly becoming popular as a surgical treatment for morbid obesity . nephrologists need to be aware of possible renal complications after bariatric surgery . we report a 54-year - old male patient who presented with progressive...
a 7 year - old , 113 cm , 17 kg , female patient with tooth decay presented for general anesthesia for tooth conservation day surgery because outpatient treatment was not possible due to her lack of cooperation . her medical history showed that she had been delivered normally after 39 weeks of gestation , weighing 2....
angelman syndrome is characterized by a partial deficit of paired autosomal chromosome 15 , which contains a subunit of the gaba ( gamma - amino butyric acid ) receptor . many drugs that act on the cns ( central nerve system ) during anesthesia are believed to exert their effects via the gaba receptors . we describ...
in addition , vascular regeneration and repair are essential for the survival of blood vessels . there are still uncharacterized and less characterized cell types in vascular adventitia , which include vascular stem / progenitor cells [ 110 ] and adventitial neuronal somata ( annies ) . the vascular adventitia is a...
a novel perivascular adventitial cell termed , adventitial neuronal somata ( annies ) expressing the neural cell adhesion molecule ( ncam ) and the vasodilator neuropeptide , calcitonin gene - related peptide ( cgrp ) , exists in the adult rat mesenteric branch artery ( mba ) in situ . in addition , we have previousl...
as one of the most common intracranial tumors in humans , pituitary adenoma is the third most common primary brain tumor after glioma and meningioma , accounting for about 15~20% of all primary intracranial tumors . the average incidence of pituitary adenoma is about 7.5~10 per 100 000 population , but has rapidly in...
backgroundalthough pituitary adenoma is a malignant tumor , it can present as invasive growth in some cases . microrna ( mir)-26a has been found to be abnormally highly expressed in pituitary adenoma , indicating possible involvement in pathogenesis . as a known target gene of mir-26a , plag1 has abnormally low expre...
northern norway covers half of norway s land area and constitutes about two thirds of the size of the uk . it has a scattered population of about 470,000 inhabitants and the main industry is fishery . there are 88 municipalities in the region and almost half ( 42 municipalities ) of them have less than 2,000 inhabi...
backgroundthe ambulance services in northern norway have undergone significant development during recent years.aimsthe objective of this study was to describe these changes in terms of tasks performed , distance driven , resources spent and level of competence in terms of education.methodsa retrospective analysis was p...
spinal cord injury ( sci ) has a devastating effect on daily life of the patients . the foremost and frustrating symptoms are the losses of sensory , motor , and/or autonomic functions [ 15 ] . spinal cord injury can be either complete or incomplete , and the symptoms for different sci individuals may vary accordin...
neuromodulators , such as serotonin ( 5-hydroxytryptamine , 5-ht ) and noradrenalin , play an essential role in regulating the motor and sensory functions in the spinal cord . we have previously shown that in the rat spinal cord the activity of aromatic l - amino acid decarboxylase ( aadc ) cells to produce 5-ht from...
pulmonary tumor thrombotic microangiopathy ( pttm ) also known as carcinomatosis endarteritis is a highly fatal respiratory complication seen in cases of malignancies especially adenocarcinomas of the stomach . there are only around 80 cases reported in literature so far including less than 10 cases where the primary...
pulmonary tumor thrombotic microangiopathy ( pttm ) is a highly fatal complication of cancer leading to acute cor pulmonale and pulmonary hypertension . we present a case of 47-year - old male patient who developed acute breathlessness and died suddenly . the pulmonary vessels at autopsy on histopathologic examinat...
teratoid wilms tumor , a rare variant of nephroblastoma , has a predominance of heterologous elements . to date less than 30 cases of teratoid wilms tumor have been reported in the literature.[13 ] there is only one case in the literature , which has the squamous epithelial component comprising 70% of the tumor . w...
teratoid wilms tumor is an unusual histological variant of nephroblastoma with predominant heterologous component . frequently present components include adipose tissue , glial tissue , muscle , cartilage or bone . the presence of squamous epithelial component on the other hand is rarely reported . we describe a ...
if this balance is disrupted , demineralization will progress , leading to a deterioration of the tooth structure . calcium and phosphate are lost from the subsurface enamel , resulting in the formation of a subsurface lesion . at this early stage , the caries lesion is reversible via a remineralization process inv...
aim : the objective of this study was to quantitatively evaluate the remineralization potential of casein phosphopeptide - amor - phous calcium phosphate paste on enamel subsurface lesions using scanning electron microscopy with energy dispersive x - ray analysis ( sem - edx).materials and methods : ninety enamel speci...
hypertension and type 2 diabetes mellitus ( dm ) are among the main risk factors for the development of cardiovascular disease ( cvd ) . endothelial dysfunction , associated with dm and hypertension , is considered an early marker of vascular complications and a pathophysiological determinant of atherogenic processes...
abstracthypertension and type 2 diabetes mellitus ( dm ) are among the main risk factors for the development of cardiovascular disease . pharmacotherapy for dm should not only improve blood glucose control , but also provide beneficial glucose - independent cardiovascular effects . the central systolic blood pressu...
we analyzed the amino acid sequence of the receptor binding site of ha from the isolate a / jiangxi - donghu/346 - 1/2013 ( h10-jd346 ; global initiative on sharing avian influenza data [ gisaid , http://www.gisaid.org ] accession no . epi530526 ) from the first patient infected by influenza a(h10n8 ) virus . in addi...
three cases of influenza a(h10n8 ) virus infection in humans have been reported ; 2 of these infected persons died . characterization of the receptor binding pattern of h10 hemagglutinin from avian and human isolates showed that both interact weakly with human - like receptors and maintain strong affinity for avian -...
balanitis xerotica obliterans ( bxo ) is a common penile disease , first described in 1928 by stuhmer . it has been classified as a male variant of lichen sclerosis by the international society for the study of vulvovaginal disease and is a chronic inflammatory process . whilst the exact aetiology is still poorly und...
background : balanitis xerotica obliterans ( bxo ) is a chronic , often progressive disease , which can lead to phimosis and urethral stenosis , affecting both urinary and sexual function . steroid creams are usually the first - line treatment but have a limited role and surgical intervention is frequently necessary ...
human infection by the lung fluke paragonimus westermani is endemic in parts of africa , asia , and south america . transmission of the parasite to humans primarily occurs through the consumption of raw or undercooked crabs and cray fish . patients present with a variety of clinical and radiological findings , freq...
background : human infection by the lung fluke paragonimus westermani is widely distributed in africa , asia , and south america . transmission of the parasite to humans primarily occurs through the consumption of raw or undercooked crabs . clinical features of recently diagnosed pulmonary paragonimiasis show that ...
pancreatic resection is a surgical procedure associated with significant morbidity and mortality even at specialised high - volume centres [ 13 ] . although in recent years refinements in surgical technique and perioperative management have led to a reduction in perioperative mortality , the incidence of postoperativ...
pancreatic resections are surgical procedures associated with high incidence of complications , with relevant morbidity and mortality even at high volume centres . a multidisciplinary approach is essential in the management of these events and interventional radiology plays a crucial role in the treatment of patients...
small - gauge pars plana vitrectomy ( ppv ) systems have gained wide acceptance in vitreoretinal surgery due to their potential for reduced inflammation and rapid visual recovery.1 recently , valved cannulas have been added to the vitreoretinal surgery armamentarium . they alleviate the need for cannula plugs during ...
purposevalved cannulas are a recent addition to small - gauge pars plana vitrectomy ( ppv ) and provide stable intraocular fluidics . the goal of this study was to compare outcomes and postoperative complication rates of valved vs nonvalved cannula small - gauge ppv for repair of retinal detachments ( rds ) complicat...
although few would deny that consciousness and attention are intimately intertwined , their precise relationship remains unclear . generally speaking , the first view holds that attention is neither necessary nor sufficient for consciousness ( lamme , 2003 ; koivisto et al . , 2005 ) . according to this perspective ,...
most research on the relationship between attention and consciousness has been limited to perception . however , perceptions are not the only kinds of mental contents of which we can be conscious . an important set of conscious states that has not received proper treatment within this discussion is that of memories...
it is widely accepted among pediatric health care providers that the risks of developing coronary artery disease ( cad ) start in early life . hypertension ( ht ) is a major modifiable risk factor in the development of cad . identification of ht at an early age may allow early intervention to prevent future end org...
over the past several decades , childhood hypertension has undergone a considerable conceptual change , as hypertension is a predictor of future development of cardiovascular disease in adults . childhood hypertension has distinctive features that distinguish it from hypertension in adults . pediatric hypertension ...
it is a discipline which explores whether human behaviors are good or bad , right or wrong , and sees itself as the science of moral act . in organizations , including educational institutions , ethics can be defined as a set of formal and informal standards for directing people how to guide their behavior . generall...
background : although nursing faculties may believe that they possess a core of knowledge about ethical interactions with students , they may unwittingly risk crossing an ethical boundary in the learning environment . the ethical dimension in education exists because the instructor has authority to contribute to or i...
from a functional perspective , the swallowing process is composed of 3 phases , namely the oral , pharyngeal , and esophageal phases . in general , dysphagia caused by neurological disorders the pharyngeal phase is defined as the process from pharyngeal swallowing to complete passage of food boluses through th...
[ purpose ] this study aimed to investigate the effect of simultaneous application of postural techniques and expiratory muscle strength training on the enhancement of the swallowing function of patients with dysphagia caused by parkinson s disease . [ subjects and methods ] the subjects of this study were 18 p...
increased rate of depression among individuals with rheumatoid arthritis ( ra ) in comparison with the general population has been described previously ( 1 , 2 ) . it has also been shown that depression can be associated with reduced health - related quality of life ( 3 ) and weakness ( 4 ) in patients with ra , whic...
backgroundincreased prevalence of depression among patients with rheumatoid arthritis ( ra ) has been described previously . however , the impact of depression among iranian patients has not yet been investigated.objectiveshere , the prevalence of depression was assessed and the effect of disease - related characterist...
patients with advanced fecd ( modified krachmer grade 5 or 6 ) requiring corneal transplantation and control participants without guttae ( grade 0 ) were enrolled in a mayo clinic institutional review board - approved hereditary eye disease study . fecd grade was established by slit lamp biomicroscopy using specular ...
purposeto identify rna missplicing events in human corneal endothelial tissue isolated from fuchs ' endothelial corneal dystrophy ( fecd).methodstotal rna was isolated and sequenced from corneal endothelial tissue obtained during keratoplasty from 12 patients with fecd and 4 patients undergoing keratoplasty or enucleat...
cysteinyl leukotrienes ( cyslts ) , specifically lts c4 , d4 , and e4 , are generated predominantly by cells of the innate immune system following exposure to allergens , proinflammatory cytokines , and other types of receptor - dependent stimuli . the resultant mobilization of ca from intracellular and extracellular...
cysteinyl leukotrienes ( cyslts ) are produced predominantly by cells of the innate immune system , especially basophils , eosinophils , mast cells , and monocytes / macrophages . notwithstanding potent bronchoconstrictor activity , cyslts are also proinflammatory consequent to their autocrine and paracrine interacti...
solitary fibrous tumor ( sft ) is a rare tumor which was first described as originating from the pleura and occurring most commonly in the thoracic cavity3,9,12 ) . however , it is now recognized that these rare tumors can occur throughout the body7,14 ) . there have been only 8 case reports of extradural spinal sf...
a solitary fibrous tumor ( sft ) is a rare neoplasm originated from the pleura , but they can occur in a variety of extrathoracic regions . although many cases of primary sft have been reported , there are extremely rare repots to date of a malignant sft in the spine or skull . a 54-year - woman visited our hospital ...
alzheimer 's disease ( ad ) is the most common form of dementia involving slowly developing , ultimately fatal neurodegeneration with massive brain atrophy especially in the medial temporal lobe , including the hippocampus ( hardy , 2006 ; haass and selkoe , 2007 ; wang et al . , 2007 ) . ad is pathologically charact...
it was evidenced that impairment of calcium homeostasis is a potential mechanism in the development of alzheimer 's disease ( ad ) . it remains , however , unclear how the calcium signaling are associated with in ad progression . here we review recent studies to discuss the relationship among the signaling of intra...
benign prostatic hyperplasia ( bph ) is a common condition affecting men older than 50 years of age . the historical gold standard has been transurethral resection of prostate ( turp ) , which is an effective procedure but is still associated with risk of bleeding . factors that influence perioperative and postoper...
introductionpostoperative blood loss after prostate surgery is thought to be associated with an increase in urinary fibrinolytic activity . tranexamic acid ( txa ) is both a potent inhibitor of plasminogen and urokinase activators and a low molecular weight substance that is excreted unchanged in the urinary tract an...
the population we tested included patients treated by physicians within the university of pennsylvania health system , which encompasses several philadelphia - area hospitals . most isolates were from outpatients seen at the hospital of the university of pennsylvania or the presbyterian medical center ; both serve th...
fluoroquinolone - resistant campylobacter jejuni has been observed worldwide and is now being seen in the united states . among patients in our health - care system in pennsylvania , fluoroquinolone - resistant c. jejuni were not observed from 1982 to 1992 ; however , resistance increased to 40.5% in 2001 . resistanc...
sensory integration refers to the neurological process by which the brain organizes sensory information from the body to produce an adaptive movement or behavior.1,2 in the united states , the prevalence of children who typically develop sensory integration dysfunction is 5%13%;3 the estimated prevalence for children h...
objectivesensory integration progresses along a normal developmental sequence . however , few studies have explored how age difference affects the way sensory integration functions in taiwanese children as they develop . therefore , this study aims to pinpoint the role of age in sensory integration.methoda purposiv...
direct pulp therapy is a technique used for the treatment of mechanical or traumatic pulp exposures , without any clinical symptoms of inflammation . removal of irritation , control of infection and biocompatibility of capping material are important factors in treatment outcome.1 also , controlling contamination of t...
objectives : the objective of this pilot study was to evaluate the effects of three different antiseptic materials on healing processes of direct pulp therapies with ca(oh)2 histopathologically.methods:twenty-eight upper and lower first molar teeth from 7 male wistar rats were used in this study . four cavities were ...
bone is a complex tissue that has the ability to heal and regenerate itself , and is continuously in the cycle of remodeling from before birth until death . the process of bone modeling and remodeling typically occurs to help the bone adapt to mechanical forces or to replace microdamaged bone with new , stronger bone...
the complex mechanisms of the bone cell - surface interactions are yet to be completely understood , and researchers continue to strive to uncover the fully optimized implant material for perfect osseointegration . a particularly fascinating area of research involves the study of nanostructured surfaces , which are b...
from the point of view of headache science , the relation between headache and typical women s diseases like endometriosis is interesting because many features of headache , and migraine in particular , suggest a relation to female hormones . from a clinical perspective , it is important to know whether disorders ar...
headache and endometriosis show some similarities in their clinical and epidemiological features that are probably due to the influence of female sexual hormones on both disorders . epidemiological studies indicate that they are comorbid disorders . however , the nature of the comorbidity is not known with certainty ...
neonatal diabetes mellitus ( ndm ) occurs within the first six months of life . depending on clinical outcomes , it is classified into transient neonatal diabetes mellitus ( tndm ) and permanent neonatal diabetes mellitus ( pndm ) . tndm , which accounts for 50% to 60% of ndm , goes into remission after treatment f...
aims . to study the clinical features , genetic etiology , and the correlation between phenotype and genotype of neonatal diabetes mellitus ( ndm ) in chinese patients . methods . we reviewed the medical records of 25 ndm patients along with their follow - up details . molecular genetic analysis was performed ....
neuralgic amyotrophy ( na)-also known as parsonage - turner syndrome or brachial plexus neuritis - is an under - recognized but distinct clinical syndrome , with a characteristic clinical presentation of an acute , severe neurogenic pain in the shoulder or arm lasting for several days or weeks , followed by muscle weak...
the aim of this paper was to report the effect of temporary and chronic spinal cord stimulation for refractory neuropathic pain in neuralgic amyotrophy ( na ) . a 35-year - old female presented with two - months history of a severe , relentless neuropathic pain of the left shoulder , forearm , palm , and fingers . ...
phenols are aromatic compounds that are characteristic pollutants in wastewater and effluents from chemicals , petrochemicals , pharmaceuticals , textiles , and steel industries . the unwholesome and environmentally unacceptable pollution effects of the phenolic effluent have been reported worldwide . phenol contam...
degradation of phenolics by members of soil microflora is an important means by which these substances are removed from the environment thus reducing environmental pollution . biodegradation by microorganisms offers unique opportunities to destroy or render phenolic compounds . a bacterium , pu1 , identified as pse...
according to traditional persian medicine ( tpm ) resources , the human digestive system includes four steps . in the first step , gastric digestion , the ingested food pours into the stomach and changes into the leachate called chylous due to the heat produced in the stomach . in the second step , hepatic digestion ...
background : according to traditional persian medicine ( tpm ) resources , the human digestive system includes four steps . in the first step , gastric digestion , the ingested food pours into the stomach and changes into the leachate called chylous due to the heat produced in the stomach . in the second step , hepatic...
unintentional injuries among children are the commonest cause of death and hospital admission worldwide , and can result in lifelong disability . they are a growing global public health problem and responsible for about 950 000 deaths in children under the age of 18 years each year . injuries can be prevented or co...
background : unintentional injuries are one of the leading causes of death and disability among children in eastern mediterranean region ( emr ) . the issue of child injuries in the emr is a major public health concern.objectives:this study aimed to present the epidemiological pattern of children 's unintentional inj...
microscopic discectomy is a standard surgical procedure for lumbar disc herniation and has been approved as a safe method to alleviate radiating pain and other neurological symptoms . however , postoperative facet joint syndrome following microscopic discectomy is a relatively common problem requiring intervention1 )...
objectivepostoperative facet joint syndrome requiring radiofrequency neurotomy ( rfn ) is a relatively common problem following microscopic discectomy . however , the efficacy of repeated rfn after microscopic discectomy has not been clearly documented . the purpose of this study was to determine the success rate a...
motivational impairments are a cardinal feature of schizophrenia , are present in the earliest phases of the illness and are a significant predictor of impaired real - world functioning ( foussias and remington , 2010 ; schlosser et al . , 2014 ) . current clinical and neuroimaging data indicate that these motivation...
amotivation in schizophrenia is a central predictor of poor functioning , and is thought to occur due to deficits in anticipating future rewards , suggesting that impairments in anticipating pleasure can contribute to functional disability in schizophrenia . in healthy comparison ( hc ) participants , reward anticipa...
obesity is nearly twice as prevalent among people with serious mental illness , including schizophrenia spectrum and mood disorders , compared to the general population . the combination of poor diet , sedentary lifestyle , metabolic effects of psychiatric medications , poverty , and elevated obesity rates have devas...
objectiveelevated obesity rates are a major contributor to the significantly reduced life expectancy impacting people with serious mental illness . with over 1.5 billion facebook users worldwide , this platform may afford opportunities for reaching individuals with serious mental illness outside professional settings...
it has been approved by the us food and drug administration for the treatment of narcolepsy associated excessive daytime sleepiness , sleep disorder related to shift work , and obstructive sleep apnea syndrome . however , at present it is being used as a lifestyle drug , especially amongst sports personnel , hardworkin...
modafinil is a psychostimulant drug , which has been approved by the us food and drug administration for the treatment of narcolepsy associated excessive daytime sleepiness , sleep disorder related to shift work , and obstructive sleep apnea syndrome . however , presently it is being used as a lifestyle medicine ; in...