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a 55-year - old man , presented to our hospital , complained of a large pelvic mass , which was found incidentally during a routine ultrasonography . the patient had no history of abdominal or pelvic discomfort , nor any abdominal or pelvic surgery . in addition , the patient had no relevant medical or family histo...
a chondrolipoma is an extremely rare form of a benign mesenchymal tumor containing mature cartilage and fatty tissue . chondrolipomas may be found in almost any part of the body , particularly in the connective tissue of the breast , head and neck area , as well as in the skeletal muscle . however , to the best of ...
esthesioneuroblastoma , or olfactory neuroblastoma , was first described by berger et al , in 1924 as l'esthsioneuropithliome olfactif.1 since then several hundred patients have been described in case series , single - institution reviews , and meta - analyses.2 3 4 5 6 7 8 9 10 11 12 13 14 15...
introduction advanced kadish stage esthesioneuroblastoma requires more extensive resections and aggressive adjuvant therapy to obtain adequate disease - free control , which can lead to higher complication rates . we describe the case of a patient with kadish d esthesioneuroblastoma who underwent multiple surgeries ...
studies from the united states , europe and hong kong indicate that young children are at risk for serious illness and hospitalization from influenza virus infection . , , , , in the united states , 80% of influenzaassociated hospitalization in children occurs in those < 5 years of age and more than half of...
background studies in north america and europe have shown that young children are at increased risk of serious complications and hospitalization from influenza infection . in thailand , however , influenza is commonly considered a mild infection that rarely requires hospitalization . an improved understanding of th...
sleep loss and sleep disorders are among the most common health problems , but are frequently overlooked . it is estimated that about one - third of people in the general population suffer from a chronic disorder of sleep and wakefulness.1 insomnia is a subjective complaint that sleep is difficult to initiate or main...
background : lactuca sativa ( garden lettuce ) is a popular salad herb . it has been in use in folk medicine since ancient times as both an appetite stimulant and as an aid to sleep . l. sativa seed oil ( sedan ) has demonstrated a pronounced sedative effect and potentiated the hypnotic effect of barbiturates in an...
dural arteriovenous fistula ( davf ) , also called dural arteriovenous shunt or malformation , consists of acquired lesions within the dura mater.11)19 ) the etiology and natural history of these lesions remain unknown.18)19)23 ) however , the clinical presentations and assessed risk of the lesions have been correlated...
we report a case of dural arteriovenous fistula ( davf ) that showed spontaneous conversion of venous drainage pattern from borden type ii to type iii within a four month period of follow - up . upon admission , the patient presented with aggravated neurologic status and newly developed seizure . after admission , ...
study participants for the gwas were drawn from two studies , the shanxi upper gastrointestinal cancer genetics project ( shanxi ) and the linxian nutrition intervention trial ( nit ) , a prospective cohort . for the second phase , we genotyped additional subjects from shanxi and nit as well as subjects from the shan...
we conducted a genome - wide association study of gastric cancer ( gc ) and esophageal squamous cell carcinoma ( escc ) in ethnic chinese subjects in which we genotyped 551,152 single nucleotide polymorphisms ( snps ) . we report a combined analysis of 2,240 gc cases , 2,115 escc cases , and 3,302 controls drawn from...
many use trimeric fusion proteins that share structural characteristics with cellular proteins of similar function 1 . since refolding of most viral fusion proteins is irreversible , triggering must be strictly regulated . while many enveloped viruses , including influenza- , rhabdo- , alpha- and flaviviruses , tak...
the measles virus entry system , constituted of attachment ( hemagglutinin , h ) and fusion proteins , operates based on a variety of natural and targeted receptors . however , the mechanism triggering fusion of the viral envelope with the plasma membrane is not understood . here we tested a model considering that ...
success of endodontic treatment relies on the accurate determination of the working length and adequate enlargement of the root canal . showed that often canals are improperly cleaned and attributed this to inadequate instrumentation due to the fact that the root canal diameter is larger than the instrument caliber u...
aim : to investigate the influence of cervical preflaring using different rotary instruments on apical file size determination.materials and methods : extracted human molar teeth were randomly divided in to eight groups ( n = 10 ) : control group ( cg ) ; la axxess group ( la ) ; hyflex group ( hf ) ; gatesglidden grou...
a primiparous 26 year old mother , 41 weeks of gestational age wanted a vaginal delivery . to provide analgesia during the delivery , an epidural catheter was inserted in the l4-l5 interspace using the loss - of - resistance technique . no cerebrospinal fluid or blood leakage was observed and the patient did not ex...
a 26 year old , healthy , 41 week primiparous woman received a patient - controlled epidural analgesia ( pcea ) and experienced paraplegia 11 hours later after a vaginal delivery . this was thought to be the result of complications from pcea but there was no specific abnormality on magnetic resonance imaging ( mri ) ...
the patient was a 28-year - old woman who was admitted to hospital because of a hepatic mass found incidentally on screening sonography . she had no previous surgical and medical problems . a physical examination and the laboratory findings on admission revealed no abnormalities . the serum alpha - fetoprotein leve...
focal nodular hyperplasia ( fnh ) is characterized by the presence a central scar with radiating fibrous septa . our case had a capsular retraction , which was the result of an extension of the central scar to the surface . in addition , a hypointense scar on the t2-weighted image and a minimal enhancing central sc...
immunoglobulin g4 -related disease ( igg4rd ) is a novel disease entity associated with high serum igg4 levels . the kidney is a distinct target organ affected by this disease entity and we report one such patient with an unusual presentation . a 57-year - old gentleman was referred with high grade intermittent fev...
pyrexia of unknown origin is a challenging clinical problem . infections , malignancies , and connective tissue diseases form the major etiologies for this condition . we report a case of a 57-year - old diabetic male who presented with fever of unknown origin for several months . the course of investigations led...
our laboratory has developed a method of particle exposure whereby anesthetized rats intratracheally inhale , at a regulated breathing rate and pressure , an aerosolized test material . this method is capable of delivering considerable doses in a short time period and , unlike the commonly used method of intratrachea...
the hav is a non - enveloped , positive - stranded rna virus that was first identified using electron microscopy in 1973 , and is classified within the genus hepatovirus of the picornavirus family.1 hepatitis a occurs predominantly in children , where it is a self - limiting and usually asymptomatic infection . while...
hepatitis a virus ( hav ) infections occur predominantly in children , and are usually self - limiting . however , 75 - 95% of the infections in adults are symptomatic ( mostly with jaundice ) , with the illness symptoms usually persisting for a few weeks . atypical manifestations include relapsing hepatitis , prolon...
hypercholesterolaemia is a major risk factor for the development of atherosclerosis and coronary heart disease ( chd ) . reducing low - density lipoprotein cholesterol ( ldl - c ) with statins lowers the risk of chd events and all - cause mortality and there is a clear relation between the degree of absolute ldl -...
aimsto compare the efficacy [ low - density lipoprotein cholesterol ( ldl - c ) lowering ] and safety of alirocumab , a fully human monoclonal antibody to proprotein convertase subtilisin / kexin 9 , compared with ezetimibe , as add - on therapy to maximally tolerated statin therapy in high cardiovascular risk patients...
information about irs was obtained from the replicate 6-month rcts ( studies co405 and co406 or gout 1 and 2 ; identifier : nct00325195 ) and the subsequent open - label extension ( ole ) study data sets ( c0407 ; identifier nct01356498 ) . briefly , these studies enrolled patients with refractory gout and sua of 8.0...
backgroundin clinical trials of pegloticase , a pegylated uricase developed for treatment of gout refractory to conventional therapy , infusion - related reactions ( irs ) were the second most frequent adverse event reported.objectivethe objective of this study was to provide a detailed account of irs with pegloticase ...
pyrimidinones have been paid increasing attention , due to their various therapeutic and pharmacological properties , such as antiviral , antibacterial , antihypertensive , and antitumor effects . more recently , they emerged as integral backbones of several calcium blockers , antihypertensive agents , -1a - antagoni...
a simple protocol for the efficient preparation of aryl and heteroaryl substituted dihydropyrimidinone has been achieved via initial knoevenagel , subsequent addition , and final cyclization of aldehyde , ethylcyanoacetate , and guanidine nitrate in the presence of piperidine as a catalyst in solvent - free under micro...
neoplastic cell lines used in this study were te-1 , te-5 , and te-8 , which were established from well- , poorly- , and moderately - differentiated escc , respectively . these cell lines were purchased from riken cell bank ( tsukuba , japan ) and cultured in rpmi-1640 medium supplemented with 10% fetal bovine ser...
esophageal cancer ( ec ) is the eighth most common cancer globally in 2012 and predominantly occurs in the man ( enzinger and mayer , 2003 ; conteduca et al . , 2012 ) . ec is classified mainly into two types , esophageal squamous cell carcinoma ( escc ) and esophageal adenocarcinoma , accounting for 6070% and 2030% ...
human parainfluenza virus type 1 ( hpiv-1 ) , which is a member of the family paramyxoviridae , is an enveloped virus with a single - stranded rna genome [ 1 , 2 ] . hpiv-1 infects the upper and lower respiratory tract and causes acute respiratory infections ( aris ) , ranging from mild infections , such as the commo...
human parainfluenza virus type 1 ( hpiv-1 ) is the most common cause of croup in infants . the aim of this study was to describe molecular mechanisms associated with il-8 production during hpiv-1 infection and the role of viral replication in mapk synthesis and activation . an in vitro model of hpiv-1 infection in ...
1 . this bioequivalence study demonstrates that the pharmacokinetic properties of gabapentin 500 mg and zolpidem tartrate 10 mg are unaffected when both treatments are taken simultaneously , compared with each drug taken alone , in healthy participants.2 . both treatments were well tolerated when taken alone and in...
objectivegabapentin is being investigated as a potential treatment for occasional disturbed sleep . this study assessed the pharmacokinetics and tolerability of gabapentin 500 mg and the commonly prescribed sedative / hypnotic zolpidem tartrate 10 mg , administered separately and in combination.methodsforty healthy...
latissimus dorsi exercises are advocated to provide muscle balance to chest and shoulder press exercises . like many strength training exercises , beliefs persist regarding the influence of exercise variations on muscle recruitment patterns . anecdotally , two beliefs assert that using a supinated grip during the p...
backgroundexercise beliefs abound regarding variations in strength training techniques on muscle activation levels yet little research has validated these ideas . the purpose of the study is to determine muscle activation level , expressed as a percent of a normalization contraction , of the latissimus dorsi , biceps...
spinal dural ateriovenous fistula ( sdavf ) is the lesion within dural leaflets due to direct arterial - to - venous shunt . dural ateriovenous fistula ( davf ) at the craniocervical junction is rare , as an uncommon type of sdavf , which has been documented in sevral case reports2,3,4,8 ) we report a patient who p...
dural ateriovenous fistula ( davf ) at the craniocervical junction is rare . we report a patient presenting with brainstem dysfunction as an uncommon onset . brainstem lesion was suggested by magnetic resonance image study . angiogram revealed a davf at a high cervical segment supplied by the meningeal branch of ...
acetylcysteine is well established as a safe and effective antidote for paracetamol poisoning , although there is uncertainty regarding the indications for treatment and most effective administration protocol [ 13 ] . a treatment nomogram was originally devised by prescott to allow identification of patients at signi...
in september 2012 , the medicines and healthcare products regulatory agency ( mhra ) substantially amended the marketing authorisation for acetylcysteine following an extensive review . the present study examined the impact of this license change on patterns of acetylcysteine use in patients presenting to hospital af...
the disease of dental caries dates back to ancient times and is the most common disease besetting human race . in spite of various preventive methods , dental caries it has been shown to be a very useful adjunct to restorative dentistry because of its unique ability to release fluoride , which is mainly responsible f...
aim : to comparatively evaluate the compressive strength , diametral tensile strength , and shear bond strength of glass ionomer cement type ix , chlorhexidine - incorporated glass ionomer cement , and triclosan - incorporated glass ionomer cement.materials and methods : in this study , glass ionomer cement type ix was...
the mucosal folds in the body of the stomach are usually less than 1 cm thick . occasionally these folds , also referred to as rugae , may thicken and enlarge , a condition known as hypertrophic gastropathy . while mntrier 's disease is most commonly associated with hypertrophic gastric folds , a variety of other dis...
infection with helicobacter pylori ( hp ) is common in many parts of the world . while most patients are asymptomatic , it causes peptic ulcer disease and malignancy in some of them . other rare conditions have occasionally been reported in association with this infection . we report a case of hypertrophic gastropa...
oligoribonucleotides were synthesized on an mm12 synthesizer ( bioautomation corp . , irving , tx ) on a 50 nmol scale with 2otbdmsphosphoramidites ( thermo fisher ) , using a 1000 unylinker support ( chemgenes , wilmington , ma ) . coupling time was 290 s for regular 2otbdms phosphoramidites , 2180 s for the dn...
abstractlong structured rnas are useful biochemical and biological tools . they are usually prepared enzymatically , but this precludes their sitespecific modification with functional groups for chemical biology studies . one solution is to perform solidphase synthesis of multiple rnas loaded with 5terminal phospha...
dyke - davidoff - masson syndrome ( ddms ) was originally characterized by its radiologic features , which include cerebral hemiatrophy and ipsilateral skull hypertrophy with hyperpneumatization of the paranasal sinuses and mastoid cells.1,2 although seizure is one of the core symptoms along with hemiparesis and mental...
dyke - davidoff - masson syndrome ( ddms ) has cerebral hemiatrophy and compensatory ipsilateral skull thickening , and is manifested by recurrent seizures and hemiparesis . we present one case with typical ddms , who had a brother suffering from epilepsy with mild imaging abnormality relevant to ddms and similar sei...
all materials for cell culture including fetal bovine serum ( fbs ) and opti - mem were obtained from gibco brl ( grand island , ny , usa ) . other media supplements , such as epidermal growth factor ( egf ) , ascorbic acid , rpmi 1640 vitamin mixture , insect lipid , and chondroitin sulfate , were purchased from sig...
purposeto establish the immortalized human corneal endothelial cell line ( ihcen ) by transducing human papilloma virus ( hpv ) 16 e6/e7 oncogenes , and to identify their characteristics when cultivated on a lyophilized human amniotic membrane ( lam).methodsprimary human corneal endothelial cells ( phcen ) were infecte...
the diagnosis of uti is very often missed in young children due to minimal and nonspecific symptoms . the developing renal cortex in young children is vulnerable to renal scarring resulting in hypertension and chronic renal failure . these morbidities in adults often have their origin in childhood . a clinically su...
introduction : development of regional surveillance programs is necessary for the development of community - acquired urinary tract infection ( uti ) guidelines , especially for sub - urban and rural areas where empirical treatment is the mainstay in the absence of proper diagnostic modalities . our aim was to evalua...
the general view of the cellular plasma membrane has evolved over the last twenty years from that of a homogeneous arrangement of lipids with embedded proteins towards that of a mosaic of microdomains , each having a specific protein and lipid composition . over the last couple of decades , evidence has accumulated for...
in the last twenty years , the general view of the plasma membrane has changed from a homogeneous arrangement of lipids to a mosaic of microdomains . it is currently thought that islands of highly ordered saturated lipids and cholesterol , which are laterally mobile , exist in the plane of the plasma membrane . lip...
one of the great challenges for wave propagation is the efficient and stable computation of waves in unbounded domains . the crucial point for these computations is that the numerical scheme avoids any reflections at the boundaries , even in case the diameter of the computational domain is just a fraction of a wavele...
we consider the second order wave equation in an unbounded domain and propose an advanced perfectly matched layer ( pml ) technique for its efficient and reliable simulation . in doing so , we concentrate on the time domain case and use the finite - element ( fe ) method for the space discretization . our un - split ...
subjects and data collection : the subjects were dogs examined at kakogawa animal hospital , kakogawa , hyogo , japan between march 2005 and april 2010 . cases were excluded , if permission of the owner , interictal , hematological and biochemical data from physical and neurologic examinations , csf findings or...
abstractepilepsy is a common neurological disorder with seizures , but diagnostic approaches in veterinary clinics remain limited . cerebrospinal fluid ( csf ) is a body fluid used for diagnosis in veterinary medicine . in this study , we explored canine epilepsy diagnostic biomarkers using gas chromatography -...
anaemia in patients with chronic kidney disease ( ckd ) is a complex condition that is associated with morbidity and mortality and a decline in quality of life ( qol ) [ 14 ] . erythropoiesis - stimulating agents ( esas ) have been shown to effectively improve and maintain haemoglobin ( hb ) levels and reduce the nee...
individualized strategies for managing renal anaemia with erythropoiesis - stimulating agents ( esas ) need to be advanced . recent outcomes from clinical studies prompted a narrowing of the guideline - recommended haemoglobin target ( 1112 g / dl ) due to increased mortality and morbidity when targeting higher haemo...
a 43-year - old male patient with cerebral palsy ( athetoid type ) was diagnosed with cervical disc herniation in addition to a symptom of 1-year history of pain radiating to the upper limb . the patient underwent a laminectomy ( c3 - 5 ) , an anterior interbody fusion ( c3 - 5 ) , a posterior interbody fusion ( c3 -...
selective cervical nerve root block is executed for patients who have symptoms of cervical radiculopathy for diagnostic and therapeutic purposes . however several catastrophic complications caused by this procedure have been reported including neurological complications . a 43-year - old male received a c5 selectiv...
traditional kava is an aqueous extract of the roots of piper methysticum and serves as a ceremonious and daily beverage or an herbal remedy for south pacific islanders . kava had also been used clinically to treat mild and moderate anxiety , based on results of numerous clinical trials . anxiolytic kava was...
anxiolytic kava products have been associated with rare but severe hepatotoxicity in humans . this adverse potential has never been captured in animal models , and the responsible compound(s ) remains to be determined . the lack of such knowledge greatly hinders the preparation of a safer kava product and l...
since 1995 , the environmental working group ( ewg ) , a united states - based environmental advocacy organization , has developed an annual list of fruits and vegetables , frequently referred to as the dirty dozen , suspected of having the greatest potential for contamination with residues of pesticides . the ewg ...
probabilistic techniques were used to characterize dietary exposure of consumers to pesticides found in twelve commodities implicated as having the greatest potential for pesticide residue contamination by a united states - based environmental advocacy group . estimates of exposures were derived for the ten most freq...
acute kidney injury ( aki ) is a major concern in intensive care unit ( icu ) patients , due to not only high incidence but also as an independent variable for poor outcome in these patients . the prevalence of aki in critically ill patients had been reported to be varying from 1.5% to 70% depending upon the populati...
acute kidney injury ( aki ) is an independent variable for poor outcome in critically ill patients . the pathophysiology of septic aki is distinct from that of non - septic aki . we studied the clinical profile and outcome of septic aki since such data is sparse in indian patients . in this single - center retrospe...
anisotropy or alignment is a critical feature of functional soft materials in living organisms , but it remains a challenge for spontaneously generating anisotropic gel materials . here we report a molecular design that increases intermolecular aromatic aromatic interactions of hydrogelators during enzymat...
they are classified into 4 grades ( grade i ii , low - grade ; grade iii iv , and high - grade ) according to the guidelines of the world health organization ( who ) . the accurate grading of gliomas has clinical significance for therapeutic decision - making , the monitoring and administration of chemoradiotherapy...
backgroundgliomas are the most common primary brain neoplasms . misdiagnosis occurs in glioma grading due to an overlap in conventional mri manifestations . the aim of the present study was to evaluate the power of radiomic features based on multiple mri sequences t2-weighted - imaging - flair ( flair ) , t1-weig...
the skin wound healing is a dynamic and complex process divided into three complementary stages : inflammatory , proliferative , and maturation . the inflammatory phase comprehends the intense leucocytes recruitment to the wound area , removal of cellular and extracellular matrix debris , and syntheses of regulatory ...
background and purpose . skin wound healing is a dynamic process driven by molecular events responsible for the morphofunctional repair of the injured tissue . in a systematic review , we analyzed the relevance of plant fractions and isolates on skin wound healing . by revising preclinical investigations with murin...
bone marrow evaluation is essential in the diagnostic evaluation of both hematopoietic and many non - hematopoietic disorders , determining the efficacy of treatment and to monitor the recovery process in patients undergoing bone marrow transplantation or marrow - ablative chemotherapy and is also part of the staging p...
bone marrow sampling remains essential in the evaluation of hematopoietic and many non - hematopoietic disorders . one common limitation to these procedures is the discomfort experienced by patients . to address whether a powered biopsy system could reduce discomfort while providing equivalent or better results , w...
zebrafish ( danio rerio ) is extensively used as a model organism in many fields , including developmental biology , cancer and immunology . there is a clear temporal separation between the innate and adaptive immune responses of this organism . zebrafish relies more on the innate immune system than mammals because...
pattern recognition receptors ( prrs ) and their signaling pathways have essential roles in recognizing various components of pathogens as well as damaged cells and triggering inflammatory responses that eliminate invading microorganisms and damaged cells . the zebrafish relies heavily on these primary defense mechan...
the vitreoretinal interface underlies a significant proportion of retinal pathology that has previously required surgical intervention . the spectrum of these diseases , while previously limited to macular holes , myopic schisis - like retinopathy and vitreomacular traction syndrome , are now suspected to also encomp...
ocriplasmin represents a new treatment option for numerous vitreoretinopathies involving an abnormal vitreomacular interface . while the drug may circumvent the traditional risks of surgical treatment , pharmacologic vitreolysis is not devoid of risk itself . this report presents two cases , one of vitreomacular tr...
common bile duct ( cbd ) cancer is a relatively rare but increasing malignancy worldwide that arises from biliary epithelium , known as a cancer with chemoresistance and poor prognosis . complete resection is the most effective and the only potentially curative treatment.1 however , at the time of diagnosis most pati...
common bile duct ( cbd ) cancer is a relatively rare malignancy that arises from the biliary epithelium and is associated with a poor prognosis . here , we report a case of advanced metastatic cbd cancer successfully treated by chemotherapy with gemcitabine combined with s-1 ( tegafur+gimeracil+oteracil ) . a 65-year -...
pachymeningitis is a rare feature of wegener 's granulomatosis ( wg ) and an uncommon initial manifestation of the disease . we demonstrate that pachymeningeal lesions refractory to conventional therapy can resolve completely by the addition of rituximab ( rtx ) to standard remedies . this case also illustrates tha...
a 27-year - old woman was admitted for intractable right - sided neck , ear , and jaw pain with gradual development of tinnitus and hearing loss . a cerebral mri showed meningo - dural enhancement , and additional diagnostic workup revealed a right pulmonary infiltrate and positive pr-3 anca . biopsies ...
our understanding of the mechanisms and patterns of international migration over time are impeded both by the lack of data and by inconsistencies in the measurement and collection of the data that are available . in fact , it is well known that the patterns of migration vary significantly depending on which country i...
due to differences in definitions and measurement methods , cross - country comparisons of international migration patterns are difficult and confusing . emigration numbers reported by sending countries tend to differ from the corresponding immigration numbers reported by receiving countries . in this paper , a metho...
temporomandibular disorders ( tmd ) are called to a group of painful conditions with a prevalence rate of 3 - 15% , in which temporomandibular joints ( tmjs ) and/or masticatory muscles are typically involved.1 - 3 patients with tmd frequently complain about multiple bodily pains outside of the orofacial regions.4,5 tm...
background : joint range of motion might affected by some factors like laxity and increase joint mobility . generalized joint hypermobility and temporomandibular joint hypermobility ( tmjh ) are reported as risk factors for temporomandibular disorders . the aim of this study was to survey the etiological factors of t...
familial hemiplegic migraine ( fhm ) is a rare form of migraine with aura that involves motor aura ( hemiparesis ) and an autosomal dominant classical migraine subtype . the prevalence of hemiplegic migraine ( hm ) was reported as at least 0.002% for the sporadic form and at least 0.003% for the familial form in denm...
we report the first korean patient with familial hemiplegic migraine type 1 , with clinical and multimodal imaging findings . a 43-yr - old man was admitted for right hemianopia and aphasia , followed by coma . mri showed only cerebellar atrophy . ct angiography showed mild vasodilation of intracranial blood vessel...
from march through november 2015 , at the people s liberation army 154 hospital in xinyang city , henan province , china , patients who were acutely symptomatic with fever and had a history of tick bites or animal contact within the past month were screened for sfg rickettsiae infection . at admission , dna was extra...
only 4 species of spotted fever group rickettsiae have been detected in humans in china . however , phylogenetic analysis of samples from 5 ill patients in china indicated infection with a novel spotted fever group rickettsia , designated rickettsia sp . xy99 . clinical signs resembled those of severe fever with th...
classically mast cells are considered critical effector cells in allergy by virtue of their potential to secrete a variety of allergic mediators . the number of mast cells is increased at sites of allergic inflammation , and there is a correlation between mast cell density in the tissue and the severity of allergic s...
abstractin addition to their well - established role in allergy mast cells have been described as contributing to functional regulation of both innate and adaptive immune responses in host defense . mast cells are of hematopoietic origin but typically complete their differentiation in tissues where they express immun...
a 40-year - old patient was admitted to the hospital on january 29 , 2004 , with fever , generalized weakness , diarrhea , and vomiting . initial blood tests showed hemoglobin level of 8.5 g / dl , leukocyte count of 4.9 x 10/l , and platelet count of 110 x 10/l . erythrocyte sedimentation rate was elevated at 88 m...
we report the first case of human melioidosis from mauritius , where burkholderia pseudomallei has never been isolated . the patient was immunocompromised , had never traveled abroad , and had a history of regular exposure to mud . she became ill at a time when rainfall was higher than the monthly average .
oxidatively modified lipoproteins , such as oxidized low - density lipoprotein ( oldl ) have been implicated in the pathogenesis of atherosclerosis and neurodegenerative diseases such as alzheimer 's disease ( ad ) [ 1 - 5 ] . this peroxidation of the low - density lipoprotein ( ldl ) molecule renders it immunogenic ...
backgroundan inverse relationship between the level of high - density lipoprotein ( hdl ) and coronary heart disease ( chd ) has been reported . in contrast , oxidized hdl ( ohdl ) has been shown to induce neuronal death and may play an important role in the pathogenesis of chd . in the present study we have investig...
the greater part of human mortality and morbidity ( certainly in the developed world ) focuses on cardiovascular disease and its risk factors , cancer , and connective tissue disease . the pathophysiology of cardiovascular disease ( endothelial damage leading to hypertension and thrombosis ) is established , whilst t...
the most frequent ultimate cause of death is myocardial arrest . in many cases this is due to myocardial hypoxia , generally arising from failure of the coronary macro- and microcirculation to deliver enough oxygenated red cells to the cardiomyocytes . the principle reason for this is occlusive thrombosis , either ...
liver transplantation is the only treatment option for patients with end stage liver disease or advanced hepatocellular carcinoma . for the last 25 years , the number of waiting list candidates has gradually increased and exceeded the number of available grafts . the number of heart beating donors has decreased ove...
the success of liver transplantation has resulted in a dramatic organ shortage . in most transplant regions 20 - 30% of patients on the waiting list for liver transplantation die without receiving an organ transplant or are delisted for disease progression . one strategy to increase the donor pool is the utilizatio...
accumulating epidemiologic evidence suggests that the effect of obesity on chronic disease risk differs by ethnicity . asians experience a higher risk for hypertension , diabetes , and cardiovascular disease at lower levels of body mass index ( bmi ) compared to caucasians [ 13 ] . for example , japanese americ...
ethnic differences in adipose tissue distribution may contribute to different chronic disease risks across ethnic groups , and adipokines may mediate the risk . in a cross - sectional study , we examined ethnic differences in adipokines and inflammatory markers as related to body mass index ( bmi ) among 183 premenopau...
3h2o ) and tq ( 2-isopropyl-5-methyl-1,4-benzoquinone ) were purchased from sigma - aldrich chemical co. ( st . louis , mo , usa ) . healthy adult ( 4-month - old ) male wistar rats , weighing 200230 g , obtained from the tunisian society of pharmaceutical industries , were used in this study . the animals were hou...
objectivealteration of the antioxidant status in the kidneys may be related to lead ( pb ) intoxication . the present study aimed to investigate the possible beneficial effect of thymoquinone ( tq ) , the major active ingredient of the volatile oil of nigella sativa seeds , on pb - induced renal antioxidant defense s...
lipoid proteinosis ( lp ) is a very rare autosomal recessive genodermatoses whose true incidence is not known . it was first described by siebenmann in 1908 and the first case series as lipoidosis cutis et mucosae was presented by a viennese dermatologist , urbach and an otorhinolaryngologist , weithe in 1929 . lat...
lipoid proteinosis ( lp ) is a rare autosomal recessive genodermatoses characterized by deposition of amorphous hyaline material in different parts of the body , especially the skin , mucous membranes of the upper aerodigestive tract , and internal organs . oral cavity is most extensively affected area by the disease...
nearly half of all dental restorations fail within 10 years , and replacement of these failed restorations accounts for 50%70% of all procedures in restorative dentistry . composites are popular filling materials because of their esthetics and direct - filling capabilities . one main problem , however , is that compo...
objectives : the present study was conducted to evaluate the effect of nanosized aluminum trioxide ( al2o3 ) particles when added to the nano - bond adhesive system and its effect on the microshear bond strength of nanocomposite resin to dentin.materials and methods : a newly developed adhesive ( nano - bond ) and one ...
ovarian cancer is the most frequent cause of death from gynaecological cancer and the fourth most frequent cause of cancer - related death in women in europe and the united states . it has the highest fatality - to - case ratio of all gynaecological malignancies , mainly due to the fact that it is characterized by ea...
introduction . we performed a review of the literature to elucidate the potential prognostic significance of serum vascular endothelial growth factor ( svegf ) levels in ovarian cancer . methods . eligible studies in english and italian were identified in medline / pubmed from vegf discovery to october 2011 . all...
failure to grasp the rationale behind cleaning and shaping concepts can increase the incidence of procedural complications such as blockage , ledge formation , apical transportation and perforations . according to the glossary of endodontic terms of the american association of endodontists , canal transportation is d...
procedural accidents leading to complications such as canal transportation have been ascribed to inapt cleaning and shaping concepts . canal transportation is an undesirable deviation from the natural canal path . herewith a case of apical transportation of root canal resulting in endodontic retreatment failure and...
gastrointestinal basidiobolomycosis is an emerging infection , with fewer than 80 cases reported in the english literature . also , a few cases of gastrointestinal basidiobolomycosis , accompanied by liver involvement as part of a disseminated disease , have been reported . this is the first case report of an isola...
introduction : gastrointestinal basidiobolomycosis is an emerging infection , with fewer than 80 cases reported in the english literature.case presentation : also , a few cases of gastrointestinal basidiobolomycosis , accompanied by liver involvement as part of a disseminated disease , have been reported.conclusions:th...
although this concept implies that every tumor is defective in one or more aspects of the cell cycle control , it clearly does not mean that oncogenesis targets only oncogenes and the cell cycle clock . development of malignancy appears to require aberrations in the cell death machinery , cell - cell and/or cell - ma...
background and objectives : the study aims at the observation of the immunohistochemical expression of cd44s in oral squamous cell carcinoma ( oscc ) and to correlate its expression with prognostic parameters.materials and methods : a total of 30 cases of oscc , - 10 cases of each well differentiated ( wd scc ) , moder...
small airways are considered the major sites of airflow limitation in patients with chronic obstructive pulmonary disease ( copd).1 structural and inflammatory changes in distal airways increase with more severe bronchial obstruction in copd.1 furthermore , association of distal airway impairment with mortality has bee...
backgroundwe investigated whether a relationship between small airways dysfunction and bronchodilator responsiveness exists in patients with chronic obstructive pulmonary disease ( copd).methodswe studied 100 ( 20 female ; mean age : 6810 years ) patients with copd ( forced expiratory volume in 1 second [ fev1 ] : 55% ...
lipase plays a key role in dietary fat absorption by hydrolyzing triglycerides to monoglycerides and free fatty acids . as such orlistat is a potent lipase inhibitor that is sold as a weight loss aid in prescription and over - the - counter formulations . it has been demonstrated that orlistat is an irreversible in...
purposeto develop a bio - assay that would be able to directly test gastrointestinal and/or dissolution samples to determine lipase activity and inhibition by orlistat.methodsenzyme assays were performed with porcine pancreatic lipase and para - nitrophenyl palmitate ( pnpp ) in ph 8.0 reaction buffer at 37c . substr...
reports of constitutional ring chromosome 22 , r(22 ) are rare . the majority of cases with r(22 ) are formed de novo , but there are a few reports of familial transmission1 ) . a breakpoint resulting in the loss of the short arm and satellite material has few clinical consequences , whereas a breakpoint on the lon...
reports of constitutional ring chromosome 22 , r(22 ) are rare . individuals with r(22 ) present similar features as those with the 22q13 deletion syndrome . the instability in the ring chromosome contributes to the development of variable phenotypes . central nervous system ( cns ) atypical teratoid rhabdoid tum...
it is well known that the anterior mandible contains several anatomical landmarks such as intra bony vascular canal , which is named the mandibular incisive canal ( mic ) and lingual foramen . the lingual foramen is situated in the midline of the mandible , at the level of , superior or inferior to the mental spines ...
background : some studies have been performed on assessing the anatomical variations of lingual foramen and its bony canals , in many different countries but no study has been performed in iran yet . the purpose of this study is to assess the anatomical variations of lingual foramen and its bony canals with cone - be...
immunocompromised patients are susceptible to bacterial , fungal , and viral infections that healthy immune systems usually conquer . chemotherapy and radiation treatments can harm or destroy white blood cells such as t cells , b cells , and neutrophils key components of the immune system . the patient is immunoco...
alternanthera brasiliana ( l. ) kuntze ( amaranthaceae ) is a herbaceous plant used against inflammation , cough , and diarrhea in brazilian popular medicine . in our preliminary study , promising wound healing activity of methanol extract of leaves of a. brasiliana ( meab ) was observed in normal excision and incisi...
breast cancer is the leading cause of cancer deaths among women in developed countries [ 1 , 2 ] . the use of natural dietary compounds to block or delay the onset of cancer is a promising chemoprevention strategy [ 37 ] . the purpose of these chemopreventive agents is to suppress cancer cell proliferation , induce...
research efforts investigating the potential of natural compounds in the fight against cancer are growing . tannic acid ( ta ) belongs to the class of hydrolysable tannins and is found in numerous plants and foods . ta is a potent collagen cross - linking agent ; the purpose of this study was to generate ta - cross -...
circumscribed palmo - plantar hypokeratosis ( cph ) is a rare dermatosis , first described by perez et al . in 2002 . only about 50 cases have been described in the literature so far , of which two were with a unique plantar localization . the disorder usually affects women ( with a female : male ratio of 4:1 ) , w...
circumscribed palmar or plantar hypokeratosis is a rare benign epidermal malformation of the skin . clinically it shows asymptomatic , well - circumscribed , and depressed erythema persisting for many years on the palms or soles . its main histopathologic feature shows a characteristic epidermal depression with an ...
it contains various enzymes of which some are involved in milk biosynthesis pathway in the mammary gland while the others are specific for the digestion of proteins , fats or carbohydrates , facilitating the infant 's ability to exploit these hm major constituents . hm also contains biologically active compounds , ho...
objectivehuman milk ( hm ) is the ideal food for all newborns and infants . apart from various bioactive compounds , including cytokines , antibodies , hormones , vitamines , it also contains polyamines , such as spermine ( sp ) , spermidine ( spd ) and putrescine ( put).aimthe present study investigated polyamine me...
the online version of this article doi:10.1007/s10886 - 007 - 9404 - 0 contains supplementary material , which is available to authorized users . plants respond to herbivore attack with an array of changes in plant chemistry , morphology , and physiology , which frequently result in the increased resistance of plants...
lima bean ( phaseolus lunatus ) features two indirect anti - herbivore defenses emission of volatile organic compounds ( vocs ) and secretion of extrafloral nectar ( efn)which are both inducible upon herbivore damage . in a previous field study , lima bean benefited from the simultaneous induction of the two defense...
aquatic insects are a major group of arthropods which at least one stage of their life cycle occurs in water . most of them live in water in primary stages that fallowed by terrestrial adult ( eg , ephemeroptera , odonata , plecoptera , trichoptera , megaloptera ) . semi aquatic insect are only associated with aquati...
background : aquatic insects are the major groups of arthropods that spend some parts of their life cycle in the water . these insects play an important role for transmission of some human and animal diseases . there is few information about the aquatic insects fauna of iran.methods:to study the aquatic insects fau...
acute coronary syndromes ( acs ) continue to be a major cause of morbidity and mortality . data from the united states and europe have reported a decrease in the incidence of stelevation myocardial infarction ( stemi ) with an increase in nonstelevation myocardial infarction ( nstemi ) in the past decade . current ...
backgroundthere has been a paradigm shift in the definition of timing of early invasive strategy ( eis ) for patients admitted with nonstelevation myocardial infarction ( nstemi ) in the last decade . data on trends of eis for nstemi and associated inhospital outcomes are limited . our aim is to analyze temporal tr...
menarche , an important milestone of sexual development , signals the end of puberty and the beginning of reproductive life in females [ 1 , 2 ] . both early and delayed menarche have been associated with increased cardiovascular disease ( cvd ) risk factors ( including metabolic syndrome ) and disease in adolescent ...
we examined associations of age at menarche and menstrual characteristics with the risk of preeclampsia among participants ( n = 3,365 ) of a pregnancy cohort study . data were collected using in - person interviews and medical record abstraction . logistic regression was used to estimate adjusted odds ratio ( or )...
with the rapid development of dna microarray technology , we can now get the expression levels of thousands of genes via one single experiment with a relative cheap cost 1 . , 2 .. these microarray data are essential in analyzing health situation of the human body and recognizing symptoms of human illnesses . mathe...
microarray data based tumor diagnosis is a very interesting topic in bioinformatics . one of the key problems is the discovery and analysis of informative genes of a tumor . although there are many elaborate approaches to this problem , it is still difficult to select a reasonable set of informative genes for tumor...
a devastating consequence of the worldwide obesity epidemic is a steady rise in the number of patients with type 2 diabetes ( t2d ) . the global prevalence of t2d is estimated at 347 million currently , and this number is projected to increase to 552 million by 2030 . in the united states alone , 29.1 million individ...
our current understanding of glucose homeostasis is centered on glucose - induced secretion of insulin from pancreatic islets and insulin action on glucose metabolism in peripheral tissues . in addition , however , recent evidence suggests that neurocircuits located within a brain - centered glucoregulatory system wo...
the incidence of b - cell neoplasms in europe has been estimated at approximately 21 per 100,000 . optimization of conventional cytostatic regimens through addition of tumor - specific anti - cd20 monoclonal antibodies ( mabs ) or dose intensification followed by autologous / allogeneic stem cell transplantation has ...
antibody - drug conjugates ( adcs ) have evolved as a new class of potent cancer therapeutics . we here report on the development of adcs with specificity for the b - cell lineage specific ( surface ) antigen cd22 being expressed in the majority of hematological malignancies . as targeting moiety a previously gener...
maxillofacial defects may have a profound psychological impact on the patient . with the rehabilitation of these defects , we not only restore normalcy to the patient 's face , but also restore his self - image and the ability to function and interact in a social environment , thus giving him the confidence needed to l...
burns can leave a patient with a severely debilitating disability even after treatment . the objectives of burn rehabilitation are to minimize the adverse effects caused by the injury while rehabilitating the patient 's physical and psychological well - being , maximizing social integration . long - term success of...
the all of isolates of g. umbellata and companion fungus used in this study were isolated by guo ( 2002 ) in shanxi province of china . they were maintained in petri plates on a wba medium ( g / l : wheat bran 30 , glucose 20 , kh2po4 3 , mgso4 1.5 , agar 15 , adjust ph to 6.0 ) at 22 to 24 under dark condition . t...
morphological characteristics of hyphal interaction between grifola umbellata ( pers . ex fr . ) pilat and its companion fungus which related to sclerotia formation from hyphae were investigated by external observations , light microscopy and transmission electron microscopy ( tem ) . external observations showed t...
the cranial bones are separated by sutures and fontanelle which will accommodate the growing brain . premature closure of one or more of these sutures results in cessation of skull bone growth perpendicular to the suture with compensatory expansion of the skull parallel to the closed suture . this will result in de...
we are reporting a rare case of i - cell disease presenting with craniosynostosis . an 11-month - old child presented with abnormal head shape , developmental delay and bent bones . we planned for corrective surgery for craniosynostosis , but on genetic analysis i - cell disease was confirmed . after explaining the p...
adequate polymerization is a crucial factor in obtaining the optimal physical performance of resin composite . the polymerization depends on chemical composition filler content , photoinitiators , shade , and thickness of composites ; it also correlated with the irradiation time and intensity , as well as the distanc...
objective : the aim of this study was to evaluate the effect of increased exposure time and light intensity on microhardness of cured composite through different thicknesses of tooth structure in primary teeth.materials and methods : one hundred and seventy cylindrical resin composite specimens were prepared . all sp...
after the first description of tunnel widening ( tw ) following anterior cruciate ligament ( acl ) reconstruction in the 1990s,1 the condition has been reported in many other studies.2345678 the correlation between tw and the clinical outcomes of acl reconstruction remains unclear ; however , many researchers have inve...
background : tunnel widening ( tw ) after anterior cruciate ligament ( acl ) reconstruction can be a serious complication , and there is controversy over how to prevent it . this study aimed to suggest surgical approaches to prevent tw using an allo - achilles tendon graft , and then to evaluate tw after these surgic...
pleomorphic xanthoastrocytoma ( pxa ) , first described by kepes et al.14 ) , is a rare neoplasm that accounts for 1% of all astrocytic tumors . pxas are supratentorial and involve the temporal lobe , so the most common presentation is seizure3,6,12 - 14 ) . the histologic features of the tumor are marked cellular ...
objectivepleomorphic xanthoastrocytoma ( pxa ) is a rare primary low - grade astrocytic tumor classified as who ii . it is generally benign , but disease progression and malignant transformation have been reported . prognostic factors for pxa and optimal therapies are not well known.methodsthe study period was janu...
cancer patients showed an increased risk of pulmonary embolism ( pe ) compared with the general population.1,2 these patients are subject , during the follow - ups , to imaging studies , including total body computer tomography ( ct ) with contrast and positron emission tomography ct , to assess the extent of the mal...
introductionin cancer patients , the chest computer tomography ( ct ) can be used to identify asymptomatic pulmonary embolism ( ape ) . in most cases , these patients are treated with anticoagulant drugs for at least 3 months . the american college of physicians recommend treatment of these patients as patients wit...
prior to this study , the affected index patient in family 1 was prescreened for smn1 mutations . whole exome sequencing ( wes ) was performed by axeq technologies ( seoul , south korea ) using the illumina ( san diego , ca ) trueseq kit to generate sequencing data . annotated wes data were examined for variants in...
objective : to describe the phenotypes in 2 families with vaccinia - related kinase 1 ( vrk1 ) mutations including one novel vrk1 mutation.methods:vrk1 mutations were found by whole exome sequencing in patients presenting with motor neuron disorders.results:we identified pathogenic mutations in the vrk1 gene in the aff...
noncancerous causes of bronchoesophageal fistula ( bef ) are rare and in a majority of the cases are due to trauma or infection , the most common being granulomatous disease . the combination of mediastinal lymphadenopathy and cough following intake of food should alert the treating clinicians about possibility of tu...
we report a case of bronchoesophageal fistula associated with tuberculosis . a 25 year old woman presented to us with 3 month history of cough worsening with deglutition . radiological examination revealed mediastinal lymphadenopathy and bronchoscopy with esophagoscopy confirmed the presence of fistulous communica...
the energy detector ( ed ) has been widely proposed for spectrum sensing ( ss ) in cognitive radio ( cr ) owing to its design simplicity , fast sensing periodicity , and ability to detect primary user ( pu ) signal without a priori knowledge of its waveform structure ( except for the knowledge of noise statistics ) [ 1...
a real valued neural network ( rvnn ) based energy detector ( ed ) is proposed and analyzed for cognitive radio ( cr ) application . this was developed using a known two - layered rvnn model to estimate the model coefficients of an autoregressive ( ar ) system . by using appropriate modules and a well - designed dete...
multiple sclerosis ( ms ) is an autoimmune disease of the central nervous system that causes myelin destruction and axonal damage in the brain and spinal cord . it is the leading cause of nontraumatic neurological disability among young adults and is associated with a variety of debilitating symptoms , including fati...
objectives . to assess the relationship between nocturnal polysomnographic ( psg ) findings and a group of key self - reported symptoms fatigue , tiredness , lack of energy , and sleepiness among sleep - laboratory referred patients with and without multiple sclerosis ( ms ) . methods . psg and questionnaire data...
intensity - modulated radiation therapy ( imrt ) is one of the treatment choices for localized prostate tumor irradiations . imrt is often delivered with low - energy photons , viz . , below 10 mv . these deep - seated prostate tumors were earlier treated with 3d - conformal radiation therapy ( 3d - crt ) using hig...
the goal of the present study was to study the effects of low- and high - energy intensity - modulated photon beams on the planning of target volume and the critical organs in cases of localized prostate tumors in a cohort of 8 patients . to ensure that the difference between the plans is due to energy alone , all othe...
alzheimer s disease ( ad ) is a common neurodegenerative disorder , which accounts for 60%80% of all cases of dementia . as the population ages , the prevalence of ad will rise sharply in the next few decades.1 the gradual onset and slow progression of ad pose a challenge for early differentiation from other causes o...
alzheimer s disease ( ad ) is a common neurodegenerative disorder with the earliest clinical symptom of olfactory dysfunction , which is a potential clinical marker for ad severity and progression . however , many questions remain unanswered . this article reviews relevant research on olfactory dysfunction in ad an...
the e2f transcription factor is best known for its ability to regulate cell cycle progression by coordinating a large group of genes involved in g1-to - s phase transition . e2f regulated genes include cell cycle regulators , such as cyclin eand cdc25a , and genes that encode essential components of the dna replicati...
abstractdefects in apoptotic programs contribute to a number of human diseases , ranging from neurodegenerative disorders to malignancy , and treatment failure . the genetic basis for apoptosis implies that cell death can be disrupted by mutations , raising the intriguing possibility that cell numbers can be regulate...
t - bet ( t - box protein expressed in t cells , also called tbx21 ) was firstly described in 2000 in a report examining the effects of t - bet on the differentiation of t helper 1 ( th1 ) cells . for the past 15 years , many studies have examined the functions of t - bet and have revealed multiple roles for this prote...
t - bet ( t - box protein expressed in t cells , also called as tbx21 ) was originally cloned as a key transcription factor involved in the commitment of t helper ( th ) cells to the th1 lineage . t - bet directly activates ifn- gene transcription and enhances development of th1 cells . t - bet simultaneously modul...
shock due to any reason carries a significant risk of mortality and morbidity , especially if the therapy is inappropriate . aggressive fluid and/or vasoactive therapy aimed at achieving the desired end - points of early goal directed therapy ( egdt ) is the cornerstone of management of both adults and children with ...
aims : aggressive therapy aimed at desired end - points of early goal directed therapy ( egdt ) is the cornerstone of septic shock management . a key endpoint that improves outcomes is achieving central venous saturation ( scvo2 ) > 70% . the gold standard to measure scvo2 is by a co - oximeter ( co - ox).settings ...
myeloid - derived , innate inflammatory cells provide early defense against invading pathogens by activating a diverse array of protective immune mechanisms . underlying these cells ' effector functions are the pattern recognition receptors ( prrs ) , which detect repeating molecular motifs inherent to various pathogen...
c5a is an inflammatory mediator generated by complement activation that positively regulates various arms of immune defense , including toll - like receptor 4 ( tlr4 ) signaling . the nod - like receptor pyrin domain - containing protein 3 ( nlrp3 ) inflammasome is activated by pathogen products and cellular / tissue...
the blowflies ( c. putoria ) were reared at the laboratory for the study of diptera , department of microbiology and parasitology , universidade federal do estado do rio de janeiro . adults were obtained from a stock colony originated from insects collected at the rio de janeiro zoo , quinta da boa vista park , city ...
we evaluate the effects the antibiotic gentamicin on the development of chrysomya putoria ( wiedemann , 1818 ) . third - generation , first - instar larvae were reared in a climatic chamber on 60 g of homogenate + agar 65% and were treated with three concentrations of gentamicin : 4.44 mg / ml , 13.33 mg / ml , ...
research by rodriguez ( 1 ) has asserted mcq items using three response options ( one correct answer with two distractors ) is comparable to , and possibly preferable over , traditional mcq item formats consisting of four response options ( e.g. , one correct answer with three distractors ) , or five response options...
introduction : research has asserted mcq items using three response options ( one correct answer with two distractors ) is comparable to , and possibly preferable over , traditional mcq item formats consisting of four response options ( e.g. , one correct answer with three distractors ) , or five response options ( e.g...
on august 3 , 2012 , fever developed in a previously healthy 63-year - old woman who lived in chuncheon - si , gangwon province , south korea ; the same day , she noticed a lump on the left side of her neck . she visited a local clinic , and ciprofloxacin and ceftriaxone were started on the first day of illness . t...
we report a retrospectively identified fatal case of severe fever with thrombocytopenia syndrome ( sfts ) in south korea from 2012 . sfts virus was isolated from the stored blood of the patient . phylogenetic analysis revealed this isolate was closely related to sfts virus strains from china and japan .
chronic pancreatitis is an inflammatory condition that may result in progressive parenchymal damage and fibrosis . the destruction of pancreatic tissue can lead to exocrine as well as endocrine dysfunction in addition to biliary , duodenal or gastric obstruction , pseudocysts , pancreatic ascites , pleural effusion ,...
context : chronic pancreatitis is an inflammatory condition that may result in progressive parenchymal damage and fibrosis which can ultimately lead to destruction of pancreatic tissue . fistulas to the pleura , peritoneum , pericardium , and peripancreatic organs may form as a complications of pancreatitis . this ...
there are 2 major pathological types of lung cancer , which account for approximately 85% of lung cancers : small cell lung cancer ( sclc ) and non - small cell lung cancer ( nsclc ) . lung cancer can be further divided into 3 histological types : squamous cell carcinoma , adenocarcinoma , and large cell lung cancer ...
backgroundchemokines are a family of small proteins secreted by cells with chemotactic activity , and they play important roles in cell adhesion . however , the expression of chemokine xcl2 and cx3cl1 in lung cancers in different pathological stages remains unclear.material/methodsxcl2 and cx3cl1 expression in lung c...
the crux of the problem of chronic periodontal diseases lies in the changes that occur in the bone . although , other tissues of the periodontium do get affected , yet it is the destruction of bone that is responsible for the loss of teeth . one objective of periodontal therapy is regeneration of the periodontal atta...
background and objectives : the primary goal of periodontal treatment is the maintenance of the natural dentition in health and comfortable function . the shift in therapeutic concepts from resection to regeneration has significantly impacted the practice of periodontology . the objective of the present study is to...
although any organ may be infiltrated by leukemic cells , breast infiltration is extremely rare . breast infiltration as the initial presentation or relapse of leukemia can be mistaken for a benign breast mass or primary breast cancer . to my knowledge , there has been no previous case report of leukemic infiltration...
in acute leukemia , leukemic infiltration of the breast is extremely rare . we report a case of biphenotypic acute leukemia ( bal ) that presented as a breast mass . a 30-year - old woman presented with a 4-month history of a right breast mass with nipple discharge and easy fatigue . she had received chemotherapy a...