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acute generalized exanthematous pustulosis ( agep ) is a pustular eruption , mainly drug induced , often accompanied by fever and neutrophilic leukocytosis appearing as scarlatiniform erythema over the flexures evolving into numerous tiny non - follicular pustules . we report a case of agep to the epidermal growth fa...
acute generalized exanthematous pustulosis ( agep ) is a pustular eruption , mainly drug induced often accompanied by fever and neutrophilic leukocytosis presenting as scarlatiniform erythema over the flexures evolving into numerous tiny non follicular pustules . we present a case report of a 56-year old woman , who ...
post - stroke depression ( psd ) is one of the symptoms observed in stroke patients . the prevalence of psd is high , as it is diagnosed in 53% of patients at 3 months and in 42% of patients at 12 months after stroke1 . additionally , psd has been reported to have a high incidence even 1 month from the onset of...
[ purpose ] there have been no investigations into the improvement of activities of daily living among patients suffering from post - stroke depression on admission to convalescent rehabilitation wards in japan . this study aimed to assess the improvement of activities in daily living in patients with or withou...
aging is an important risk factor for metabolic disorders , including obesity , impaired glucose tolerance , and type 2 diabetes ( t2d ) . it has been reported that the prevalence of t2d increases with age and peaks at 6074 [ 24 ] . almost one third of the elderly have diabetes and three quarters have diabetes or p...
aging is a risk factor for impaired glucose tolerance and diabetes . of the reported 25.8 million americans estimated to have diabetes , 26.9% are over the age of 65 . in certain ethnic groups , the proportion is even higher ; almost 1 in 3 older hispanics and african americans and 3 out of 4 pima indian elders hav...
head injury is a trauma to the head that may or may not include injury to the brain . road traffic accidents ( rtas ) constitute a considerable concern to the general public and may be a major cause of traumatic head injury in nigeria . mortality rate from rtas in nigeria is higher than those of both the industrial...
background : traumatic brain injury ( tbi ) is accompanied by substantial accumulation of biomarkers of oxidative stress and depletion of antioxidants reserve which initiate chain reactions that damage brain cells . the present study investigated the role of ascorbic acid and -tocopherol on the severity and managemen...
common variable immunodeficiency ( cvid ) is a heterogeneous group of diseases characterized by hypogammaglobulinemia and repeated , predominantly , bacterial infections . b lymphocytes , however , show defects of differentiation and proliferation after antigen stimulation . the number of plasma and memory cells is r...
common variable immunodeficiency ( cvid ) is the most frequent clinically manifested primary immunodeficiency . according to clinical and laboratory findings , cvid is a heterogeneous group of diseases . recently , the defects of molecules regulating activation and terminal differentiation of b lymphocytes have been ...
prolonged pregnancy occurs in approximately 10% of all singleton pregnancies and is associated with an increased risk of fetal macrosomia , intrapartum fetal heart abnormalities , meconium staining , perinatal death , and cesarean delivery ( 1 - 3 ) . an early prediction of this condition is important because several...
this study was done to evaluate transvaginal ultrasonographic measurement of cervical length at 20 to 24 weeks and 37 weeks as a predictor of prolonged pregnancy ( defined as a pregnancy that extended beyond 41 + 2 weeks of gestation [ 289 days ] ) in nulliparous women . this prospective observational study enrolled ...
nurr1 also known as nr4a2 , belongs to the nuclear receptor superfamily of transcription factors , is highly expressed in midbrain dopaminergic ( da ) neurons , and plays an essential role in the development , survival and function maintenance of midbrain da neurons . nurr1 is a potential target for parkinson 's dise...
background : nurr1 plays an essential role in the development , survival , and function maintenance of midbrain dopaminergic ( da ) neurons , and it is a potential target for parkinson 's disease ( pd ) . nurr1 mrna can be detected in peripheral blood mononuclear cells ( pbmcs ) , but whether there is any association...
thermodynamic database for proteins and mutants ( protherm ) and thermodynamic database for protein nucleic acid interactions ( pronit ) are two comprehensive , integrated databases that document experimentally determined thermodynamic parameters published in the literature . both protherm ( 14 ) and pronit ( 5 ) ...
protherm and pronit are two thermodynamic databases that contain experimentally determined thermodynamic parameters of protein stability and protein nucleic acid interactions , respectively . the current versions of both the databases have considerably increased the total number of entries and enhanced search interfac...
a balanced response to pathogens and other immune stimuli is important to maintain physiologic homeostasis . however , whereas infectious agents may cause organismal death if the immune response is not properly activated , hyperactivated or inappropriately timed immune responses can also lead to various pathologies . ...
autoimmune disorders constitute a major and growing health concern . however , the genetic and environmental factors that contribute to or exacerbate disease symptoms remain unclear . type i interferons ( ifns ) are known to break immune tolerance and be elevated in the serum of patients with autoimmune diseases su...
diabetes contributes strongly to the risk of cvd with a risk that is increased four to six times , both for stroke and myocardial infarction . the increase in risk for myocardial infarction seem to be more pronounced in women than in men . the prevalence of igt in the general population is 23 times higher than that...
backgroundpatients with impaired glucose tolerance ( igt ) have an increased risk of cardiovascular disease ( cvd ) that is independent of traditional risk factors . hence , slightly elevated glucose levels , even in the non - diabetic range , might be associated with increased macrovascular disease.methodswithin the n...
thoracic disk herniation is a rare surgical entity that is estimated to account for 0.25 to 1.8% of all spinal herniated disks,1 2 3 4 with an estimated incidence of 1 per million patient - years.2 they usually present between the third and sixth decades with a female predilection.5 hott et al described giant cal...
study design case series and review of the literature.objective to review the management of giant calcified disks in our large cohort and compare with the existing literature . we discuss our surgical technique.methods twenty - nine cases of herniated thoracic disk between 2000 and 2013 were reviewed . eighte...
having an almost unlimited capacity to regenerate tissues lost to age and injury , planarians have long fascinated naturalists . in the western hemisphere alone , their documented history spans more than 200 years . planarians were described in the early 19th century as being immortal under the edge of the knife ( 1 ...
the emergence of regenerative medicine has raised the hope of treating an extraordinary range of disease and serious injuries . understanding the processes of cell proliferation , differentiation and pattern formation in regenerative organisms could help find ways to enhance the poor regenerative abilities shown by man...
a current trend in catalysis sees a refocus on the catalytic action of the individual parts of a more complex catalyst entity . as many catalyst systems represent a combination of ( noble ) metals and ( oxidic ) supporting materials , the latter are increasingly studied with respect to their intrinsic surface...
comparative ( electro)catalytic , structural , and spectroscopic studies in hydrogen electro - oxidation , the ( inverse ) water - gas shift reaction , and methane conversion on two representative mixed ionic electronic conducting perovskite - type materials la0.6sr0.4feo3 ( lsf ) and srti0.7fe0.3o3 ( stf ) we...
animals : the research was approved and overseen by the animal experiments committee of riken ( wako , japan ) and was conducted in accordance with the institutional guidelines for experiments using animals . common marmosets were reared at the riken brain science institute ( wako , japan ) , maintained at 27c ...
use of the common marmoset ( callithrix jacchus ) as a non - human primate experimental animal has increased in recent years . although wasting marmoset syndrome ( wms ) is one of the biggest problems in captive marmoset colonies , the molecular mechanisms , biochemical markers for accurate diagnosis and a reliab...
determinar a influncia de trs sistemas distintos de instrumentos rotatrios para alargamento cervical na determinao do comprimento real de trabalho . material e mtodos : trinta primeiros molares inferiores foram submetidos ao acesso endodntico convencional e odontometria inicial pelo mtodo visual , utilizando - se par...
objective : to investigate the influence of three different rotary systems for cervical flaring on establishment of the real working length . material and methods : thirty mandibular first molars were submitted to conventional endodontic access and initial working length measurement , followed by irrigation / suction...
lobular capillary hemangioma ( lch ) , also known as pyogenic granuloma , is a benign , rapidly growing , hypervascular lesion . its usual locations are the skin and mucous membranes of the head and neck , the nasal cavity being a rare site of origin.1 2 its etiopathogenesis is not fully established , although an a...
background lobular capillary hemangioma is a rare benign tumor , most frequently located in the head or neck region , the nasal cavity being uncommonly affected . its etiopathogenesis is not fully established , although traumatic and hormonal factors have been implied . case description a 50-year - old female pat...
the major aim of root canal therapy is to prevent and treat periradicular inflammation by eliminating microorganisms from the root canal system . the methods commonly used for this purpose include root canal preparation using different instruments and irrigants , adequate filling , and coronal restoration . c...
the development and maintenance of the sealing of the root canal system is the key to the success of root canal treatment . the resin - based adhesive material has the potential to reduce the microleakage of the root canal because of its adhesive properties and penetration into dentinal walls . moreover , the...
the therapeutic value of medicinal plants has long been exploited for the management of various disease conditions in traditional practice . this practice has gained appreciable acceptance in health care delivery in developing and developed nations with the notion that they are relatively harmless , but research is beg...
the subchronic effect of aqueous stem bark extract of khaya senegalensis on some biochemical , haematological , and histopathological parameters of rats was investigated . the rats were divided into six groups of five rats per group . groups i to vi were administered graded doses of 0 , 400 , 800 , 1200 , 1600 , an...
colorectal cancers ( crcs ) are among the most common cancers in the world . in developed countries , 6% of general population are at risk for crc and it accounts for 10% of newly diagnosed cases in male as well as 11% in female . surveys by a federation of european gastroenterology announced crc as the most common c...
background : the prevalence of colorectal cancer ( crc ) is rapidly increasing in iran . it holds the most prevalent cancer after skin , breast , and gastric cancers among the iranian population . the current study was designed to investigate the effects of leisure time , occupational and household physical activit...
pancreatic endocrine tumours are rare tumours , and may produce a variety of hormones including insulin , gastrin , glucagon , pancreatic polypeptide , vasoactive intestinal peptide and somatostatin . the most common pancreatic endocrine tumours are insulinomas and gastrinomas , which are respectively found within th...
pancreatic endocrine tumours are rare tumours , and arise from the types of pancreatic cells that produce hormones . these tumours may or may not secrete hormones themselves and may or may not be cancerous ( malignant ) . functioning tumours secrete a particular hormones which may cause various syndromes . the pr...
a total of 106 participants were recruited by purposive sampling in order to obtain information from subjects with actual experience of handling currently used mmvf materials ( table1 ) . they were construction workers in different professions or do - it - yourself consumers aged between 18 and 65 years . forty - ...
backgroundman - made vitreous fibres ( mmvfs ) are used in products for insulation and as reinforcement in materials . contamination of the skin may arise through direct or indirect contact , and from the deposition of airborne fibres . the scientific basis regarding the effects on skin of mmvfs dates from 19701980...
the guglielmi detachable coil ( gdc ) is the first detachable coil approved by the food and drug administration of the united states for treating intracranial aneurysms4,7 ) . although the gdc has been demonstrated as safe and effective for endovascular treatment of intracranial aneurysms , there have been several re...
objectivethe purpose of this study was to retrospectively evaluate and compare the incidence of diffusion - weighted image ( dwi ) lesions between the guglielmi detachable coil ( gdc ) and the target coil for treating unruptured intracranial aneurysm.methodsfrom 2010 to 2011 , consecutive 222 patients with an intracran...
systemic lupus erythematosus ( sle , lupus ) is a complex inflammatory illness with varied clinical presentations , providing management and assessment challenges to patients and practitioners [ 1 , 2 ] . sle patients live with daily background symptoms and only a few obtain symptom - free periods . a life with lup...
individuals living with lupus commonly experience daily backgrounds of symptoms managed to acceptable tolerance levels to prevent organ damage . despite management , exacerbation periods ( flares ) still occur . varied clinical presentations and unpredictable symptom exacerbation patterns provide management and asses...
visceral leishmaniasis ( vl ) is the vector - borne disease and has great importance in public health due to the fatality among children . although there is an increasing interest to vl but there is not enough approach for control measures . there are various epidemiological features of vl which indicating the need...
background : visceral leishmaniasis ( vl ) is one of the most important parasitic zoonotic diseases in the world . domestic dogs are the main domestic reservoirs of vl in endemic foci of iran . various methods , including vaccination , treatment of dogs , detection and removal of infected dogs have different result...
although the etiology of ibd is unknown , many investigators have probed whether a pathogenic cause can be attributed to onset of disease , either in full or in part.5 , 6 , 7 although no pathogen has been shown consistently to be associated with ibd , a subset of cd patients do show increased prevalence of a unique en...
pathobiont expansion , such as that of adherent - invasive escherichia coli ( aiec ) , is an emerging factor associated with inflammatory bowel disease . the intestinal epithelial barrier is the first line of defense against these pathogens . inflammation plays a critical role in altering the epithelial barrier and...
humans are confronted with a number of microorganisms , viruses , and parasites that require continued surveillance and defense against [ 1 , 2 ] . polymorphonuclear leukocytes ( pmns ) , monocytes , and tissue macrophages are important cells in the innate immune response to microorganisms and parasites [ 1 , 3 ] . a...
12-o - tetradecanoylphorbol 13-acetate ( tpa ) induces the differentiation of human myeloid ml-1 cells to macrophages . in the current study , the expression , responsiveness , and regulation of toll - like receptors ( tlrs ) in tpa - induced ml-1-derived macrophages were investigated . we have found that tpa - ind...
nonalcoholic fatty liver disease ( nafl ) is a term applied to the accumulation of fat in the liver in the absence of alcohol consumption . nafl refers to a wide spectrum of liver damage ranging from simple steatosis to non - alcoholic steatohepatitis ( nash ) to advanced fibrosis and finally , cirrhosis . the clin...
background non - alcoholic fatty liver ( nafl ) includes a spectrum of diseases ranging from simple hepatic steatosis to nonalcoholic steatohepatitis ( nash ) and cirrhosis . nafl is typically seen in association with obesity , diabetes and hypertriglyceridaemia . in order to seek the role of diet therapy in treatm...
study of prescriptions is considered as part of drug utilization , which encompasses the study of marketing , distribution and prescription of various drugs in society , along with evaluation of its medical , social , and economic consequences. the basic aim of studying drug utilization is to encourage and facilitate...
background : there is a lack of national level data from india on prescription of psychotropics by psychiatrists.aim and objective : this study aimed to assess the first prescription handed over to the psychiatrically ill patients whenever they contact a psychiatrist.materials and methods : data were collected across 1...
isotretinoin is a vitamin a synthetic analogue that has been widely used by dermatologists in the treatment of acne . among the many adverse effects of isotretinoin , eye dryness , corneal and retinal abnormalities , myalgia , true myopathy , psychiatric problems , and several autoimmune disorders have been described...
introductionthere are many adverse effects that have been described for isotretinoin . to the best of our knowledge , this is the first report of a possible association of oral isotretinoin intake with autoimmune thyroiditis and ocular myasthenia gravis ( omg).case presentationa 19-year - old caucasian male , who had...
a 40-year - old colombian man living in central colombia , bogota , was referred to local hospital for turbid white urine that had appeared 2 months earlier . milky. the phenomenon was intermittent : the patient would pass discoloured urine during 4 or 5 days without complaints of fever , burning or urgency . thereaf...
turbid white urine albinuria is defined as a urine discoloration described as milky or cloudy . one of the most frequent causes of turbid white urine is chyluria complicating filariasis ( table 1 ) . the extant causes of albinuria are non parasitic and rare . amongst their aetiologies stand excessive mineral sed...
stress granules ( sgs ) are large cytoplasmic rna - protein assemblies that form during cellular stress , and play a pivotal role in the integrated stress response ( kedersha et al . , 2013 ) . following translational arrest , polysomes disassemble leading to a sudden increase in free mrna levels in the cytoplasm . ...
summaryliquid - liquid phase separation ( llps ) of rna - binding proteins plays an important role in the formation of multiple membrane - less organelles involved in rna metabolism , including stress granules . defects in stress granule homeostasis constitute a cornerstone of als / ftld pathogenesis . polar residu...
cutaneous melanoma is a highly aggressive malignant tumor of melanocytic origin with increasing incidence in most countries of the world over the last few decades . in caucasian populations the incidence rates for cutaneous melanoma have risen faster than those for any other malignant entity over the last 30 years . ...
cutaneous melanoma is a highly aggressive malignant tumor of skin melanocytes with an increasing incidence in most countries of the world , especially in the fair - skinned populations . despite all preventive and therapeutic efforts , malignant melanoma is still the most lethal skin cancer . a delayed diagnosis re...
dendritic spines were first discovered by cajal in 1888 when studying the dendrites of purkinje cells in hens ( figures 1(a ) and 1(b ) ) : ... la superficie ... aparece erizada de puntas espinas cortas ... ( cajal , 1888 ) . ... la superficie ... aparece erizada de puntas espinas cortas ... ( caj...
dendritic spines receive the majority of excitatory connections in the central nervous system , and , thus , they are key structures in the regulation of neural activity . hence , the cellular and molecular mechanisms underlying their generation and plasticity , both during development and in adulthood , are a matter o...
acute cholecystitis as a major complication of gallstones is diagnosed in 10% to 35% of patients admitted for cholecystectomy . the anatomy at calot 's triangle in acute cholecystitis is distorted due to adhesions . as such , cholecystectomy for this condition is technically demanding , time consuming , and results...
objective : although many surgeons advocate early laparoscopic cholecystectomy ( lc ) in acute cholecystitis , debate still exists regarding its optimal timing . this study compares the outcome of lc performed within and after 72 hours of admission in patients with acute cholecystitis.methods:between january 2001 and d...
considering folkloric use of tribulus terrestris ( t. terrestris ) in diabetes and proven anti - hyperglycemic and anti - hyperlipidemic effects of t. terrestris in animal studies , we aimed to evaluate the efficacy of the hydro alcoholic extract of t. terrestris on the serum glucose and lipid profile of women with dia...
background : considering folkloric use of tribulus terrestris ( t. terrestris ) in diabetes and proven anti - hyperglycemic and anti - hyperlipidemic effects of t. terrestris in animal studies , we aimed to evaluate the efficacy of the hydro alcoholic extract of t. terrestris on the serum glucose and lipid profile of w...
mental disorders cause a substantial proportion of the burden of disease in the general population . neuropsychiatric disorders rank second in the list of disability adjusted life years ( daly ) in europe , preceded only by cardio - vascular diseases . they are also responsible for the largest part of causes ...
mental disorders cause a substantial amount of the burden of disease . although they are less frequent in rural areas , their provision of care is disproportionately lower . reimbursement claims in the federal state of mecklenburg - west pomerania of the years 2006/2007 serve as the basis for the descriptive di...
the objective of this study was to investigate the impact of long - term pyrene exposure on molting and reproduction in the model estuarine invertebrate , the grass shrimp ( palaemonetes pugio ) . grass shrimp were exposed to measured concentrations of 5.1 , 15.0 , and 63 . 4 ppb ( microg / l ) pyrene for 6 weeks ,...
in the preceding issue of critical care corstjens and coworkers investigated three different methods of glucose measurements . while data about the beneficial effects of normoglycemia in critically ill patients are conflicting and inconsistent , there is no doubt about the importance of accurate glucose measurement...
a crucial determinant for the success of intensive insulin therapy in critically ill patients is the frequent and accurate measurement of blood glucose values with immediate feedback of results . in general , therefore , this is achieved by point - of - care testing , raising the question of the best way of monitoring ...
materials recombinant human aldh2 was expressed in and purified from escherichia coli ( 16 ) . gtn ( nitropohl ampoules ; g. pohl - boskamp gmbh & co , hohenlockstedt germany ) was obtained from a local pharmacy as a 1 mg / ml aqueous isotonic solution , containing 49 mg / ml glucose monohydrate , and d...
mitochondrial aldehyde dehydrogenase ( aldh2 ) may be involved in the biotransformation of glyceryl trinitrate ( gtn ) , and the inactivation of aldh2 by gtn may contribute to the phenomenon of nitrate tolerance . we studied the gtn - induced inactivation of aldh2 by uv / visible absorption spectroscopy . ...
birds were caught by mist - nets , banded ( ringed ) , and examined for ticks at the cernek bird ringing station ( 4136n , 3605e ) in the kizilirmak delta in turkey , an internationally important wetland area for birds ( 4 ) . we conducted the study during the spring and autumn migration seasons in 2010 and 2011 and ...
we investigated migratory birds role in spreading crimean - congo hemorrhagic fever virus ( cchfv ) through attached ticks . we detected cchfv rna in ticks on migratory birds in turkey . two isolates showed similarity with cchfv genotype 4 , suggesting a role for ticks in cchfv epidemics in turkey and spread of cch...
permission was obtained from the patient included in this report . in june 2014 , a 25-year - old woman presented to the outpatient clinic with a 6-month history of progressive left hip pain . physical examination revealed mild pain with motion in the hip joint and slightly limited range of motion . radiographs sho...
we report the case of a 25-year - old woman presenting with left hip pain . a lesion was found in the proximal femoral metaphysis . benign bone tumor , such as intraosseous lipoma or liposclerosing myxofibrous tumor , was suspected based on simple radiographs and magnetic resonance images . curettage of the lesion ...
, the result can be destruction of the bone itself.1 ciprofloxacin is a broad - spectrum fluoroquinolone antibacterial agent used in the treatment of osteomyelitis caused by pathogens like staphylococcus aureus and pseudomonas aeruginosa.2 a high concentration of the drug is required for 5 weeks to several months to cu...
introductionin recent years there has been a steep increase in the number of orthopedic patients for many reasons . one major reason is osteomyelitis , caused by pyrogenic bacteria , with progressive infection of the bone or bone marrow and surrounding tissues . so antibiotics must be introduced during bone implant...
about 178,000 people develop cancer annually , with an age - standardized rate of 321.3 per 100 thousand in 2009 . this cancer incidence rate is less than the 335.0 per 100 thousand rate in the us ( 2008 ) , but higher than the 280.0 per 100 thousand in the uk ( 2008 ) and 247.3 per 100 thousand in japan ( 2008 ) . ...
cancer has been the leading cause of death in korea for the last 30 years . cancer patients ' 5-year survival rate between 2005 and 2009 was 62.0% , representing a highly advanced standard of care , as much as developed countries in the eu and the us . the korean government formulated its first 10-year plan for can...
a 64-year - old healthy man underwent phacoemulsification with intraocular lens implant on the left eye . preoperative fundus examination was normal and his best - corrected visual acuity in the left eye was 6/24 because of nuclear sclerosis . the patient was administered a single uneventful peribulbar injection co...
purtscher and purtscher - like retinopathy is a distinctive retinal syndrome characterized by ischemic retinal whitening in a peripapillary pattern . we report a case of purtscher - like retinopathy in a healthy 64-year - old man after a routine peribulbar anesthetic injection for cataract surgery . although peribu...
yttrium-90 ( y ) microsphere radioembolization is an emerging treatment for metastatic hepatic malignancies . in this procedure , 2060 micron - sized -radiation - emitting particles are administered to liver tumors using a transcatheter approach to deliver high - dose localized internal radiation . this therapy takes...
because stage 4 lung cancer is associated with dismal 5-year survival rates , new treatment approaches targeting extrapulmonary disease are necessary . yttrium-90 microsphere radioembolization is an emerging treatment for metastatic hepatic malignancies that results in high tumor response rates and extended patient s...
older adults with abdominal pain have a six- to eight - fold increase in mortality compared to younger patients [ 1 , 2 ] . intramural colonic hematomas manifest rarely as complications following blunt traumas or accompanying diseases with bleeding tendency . a 72-year - old male with cerebral palsy was admitted fo...
causes of colonic and recto - sigmoid hematomas are multifactorial . patients can present with a combination of dropping hemoglobin , bowel obstruction and perforation . computed tomography imaging can provide clues to a diagnosis of intramural hematoma . we present a case of rectal hematoma and a review of curre...
the family of mps one binder proteins ( mobs ) is highly conserved in eukaryotes . mobs represent signal transducers in essential intracellular signaling pathways through their regulatory interactions with serine / threonine protein kinases of the ndr / lats family [ 13 ] . in budding and fission yeast , mob1p and mo...
this article is the authors opinion of the roles of the signal transducer mps one binder 2 ( mob2 ) in the control of cell cycle progression and the dna damage response ( ddr ) . we recently found that endogenous mob2 is required to prevent the accumulation of endogenous dna damage in order to prevent the undesired ,...
cardio - pulmonary fitness is related to the ability to perform large muscle , dynamic , moderate - to - high exercises for a prolonged period . the performance of such exercises depends on the functional state of the cardiovascular , respiratory , and skeletal muscle systems . a variety of tests have been used to ...
objectives : it is known that exercise induces cardio - respiratory autonomic modulation . the aim of this study was to assess the cardio - pulmonary fitness by ultra - short heart rate variability.materials and methods : study population was divided into 3 groups : group-1 ( n = 40 ) consisted of military sports man...
a 60-year - old female presented with a history of serosanginous discharge and bleeding ( small amount ) per vaginum for the last 4 months . she was postmenopausal for the last 10 years with p5 + 1 + 0 + 5 . local examination revealed hard infiltrative growth destroying both cervical lips and involving the vaginal ...
abstractpyometra is an uncommon condition with an incidence of less than 1% in gynaecologic patients . spontaneous rupture of pyometra in cervical cancer presenting as generalized peritonitis is very rare . only four cases have been described in the english literature to the best of our knowledge and from a pubmed ...
laboratory information is a key driver of evidence - based clinical care and medical decision analysis . timely ( turnaround - time based ) availability of this information at the point of service is crucial in an increasingly complex medical environment . furthermore , the ability to mine for data in order to moni...
background : laboratory data account for the bulk of data stored in any given electronic medical record ( emr ) . to best serve the user , electronic laboratory data needs to be flexible and customizable . our aim was to determine the various ways in which laboratory data get utilized by clinicians in our health sy...
slow coronary flow ( scf ) phenomenon is a coronary microvascular disease diagnosed by detection of delayed dyeopacification in coronary arteries during an angiography in the lack of obstructive coronary artery disease . the incidence of scf has been reported to be approximately 1 - 7% in patients who undergo a diagn...
background and objectiveswe sought to determine the relationship between mean platelet volume ( mpv ) , platelet distribution width ( pdw ) , and platelet larger cell ratio ( p - lcr ) with slow coronary flow ( scf).subjects and methodseighty participants who underwent coronary angiography were divided into two groups ...
, many countries have made efforts to prevent and reduce tobacco use in this vulnerable age group ( 1 ) . to achieve this goal , factors that influence smoking in adolescents in different communities need to be understood . a study in turkey showed that household size , higher birth rank , school type , low academic ...
backgroundthe consumption of tobacco through a hookah is growing in popularity , especially among children and adolescents , but little is known about the determinants of hookah smoking.objectivesthe current study aimed to assess the determinants of tobacco smoking and hookah smoking in a nationally representative samp...
the epic - interact is a large prospective type 2 diabetes case - cohort study ( 16 ) nested within the epic study ( 17 ) with more than half a million adult participants recruited in the 1990s from the following 10 european countries : denmark , france , germany , greece , italy , the netherlands , norway , spain , sw...
objectiveto study the association between dietary flavonoid and lignan intakes , and the risk of development of type 2 diabetes among european populations.research design and methodsthe european prospective investigation into cancer and nutrition - interact case - cohort study included 12,403 incident type 2 diabetes c...
nonmelanocytic tumors are the most frequent.1 the national cancer institute estimates that approximately 2 million cases of nonmelanocytic skin tumors occurred in 2012 in the usa.2 these tumors cost more than us $ 400 million per year in the united states alone.3 basal cell carcinoma ( bcc ) is a nonmelanocytic skin ca...
although basal cell carcinoma ( bcc ) is the most common cancer worldwide , its metastatic dissemination is exceptional . before 2012 , we had a few treatment options available for metastatic or locally advanced cases . management of these patients was complicated due to the lack of scientific data , the deteriorat...
periodontal plastic surgery is defined as a surgical procedure performed to correct or eliminate anatomic , developmental , or traumatic deformities of gingival or alveolar mucosa . the presence of adequate zone of gingiva was considered critical for the maintenance of marginal tissue health and for the prevention...
gingival recession along with reduced width of attached gingiva and inadequate vestibular depth is a very common finding . multiple techniques have been developed to obtain predictable root coverage and to increase the width of attached gingiva . usually , the width of gingiva is first increased and then the second...
in contrast to bladder tumors ( bt ) , ureteral urothelial tumors ( uut ) are uncommon ; the bt : uut ratio is 33:1 . the incidence of uut is higher in areas affected by balkan endemic nephropathy ( ben ) , with low grade lesions prevalent . all urothelial tumors have a propensity for multicentric growth in space an...
ureteral urothelial tumors ( uut ) are uncommon ; their incidence is higher in areas affected by balkan endemic nephropathy ( ben ) , with low grade lesions prevalent . in these patients , the efficacy of conservative surgery is comparable to that of nephroureterectomy . endoscopic treatment is indicated for singl...
a 55-year - old female presented with 6-month history of progressively worsening right posterior calf pain . on physical exam , the right posterior calf appeared erythematous and warm with decreased range of motion . core needle biopsy of the right calf mass demonstrated diffuse - type giant cell tumor [ also known a...
malignant tenosynovial giant cell tumor ( tgct ) is a rare clinical entity that can arise as a recurrent lesion or can co - exist with a benign tgct lesion . malignant tgct most commonly arises in the lower extremity and tends to be clinically aggressive , with most patients developing recurrent lesions or dying . ...
chronic infection with hepatitis b virus ( hbv ) affects more than 350 million people worldwide and continues to be an important cause of morbidity and mortality . the current therapy for chronic hepatitis b ( chb ) is based on the use of immunomodulators like pegylated interferon or nucleos(t)ide analogues ( nucs ) ...
natural killer ( nk ) cells play a critical role in innate antiviral immunity , but little is known about the impact of antiviral therapy on the frequency of nk cell subsets . to this aim , we performed this longitudinal study to examine the dynamic changes of the frequency of different subsets of nk cells in chb pat...
damage control ( dc ) procedures for patients with major truncal or extremity trauma have evolved over the past 20 years and are recognized as major factors in decreasing morbidity and mortality in severely injured patients . early physiologic criteria , such as hypothermia , coagulopathy , and acidosis are used to s...
background : this study reviews our 10-year institutional experience with damage control management and investigates risk factors for early mortality.materials and methods : the trauma registry of our level i trauma centre was utilized to identify all patients from 01/96 through 12/05 who underwent initial damage contr...
type 2 diabetes ( t2d ) is a metabolic disorder characterized by high blood glucose due to insulin resistance and insulin deficiency . t2d accounts for more than 90% of all diabetes , and the prevalence of t2d and prediabetes is rapidly rising worldwide . better treatment and prevention of t2d and its complications...
the zucker fatty ( zf ) rat harboring a missense mutation ( fatty , fa ) in the leptin receptor gene ( lepr ) develops obesity without diabetes ; zucker diabetic fatty ( zdf ) rats derived from the zf strain exhibit obesity with diabetes and are widely used for research on type 2 diabetes ( t2d ) . here we establish ...
the lac insects ( coccoidea : tachardiidae (= kerriidae ) ) have been commercially harnessed to yield three useful products , viz . , resin , wax and dye , which have found a remarkably wide range of applications in food , pharmaceuticals , cosmetics , perfumes , varnishes , paints , polishes , adhesives , jewellery an...
the lac insects ( homoptera : tachardiidae ) , belonging to the genus kerria , are commercially exploited for the production of lac . kerria lacca is the most commonly used species in india . rapd markers were used for assessing genetic variation in forty - eight lines of kerria , especially among geographic races ...
2,1-borazaronaphthalenes serve as versatile isosteres of all - carbon naphthalene substructures , which allows facile emplacement of a variety of substituents about the ring in an efficient and selective manner . because of electronic desymmetrization brought about by the incorporation of a b n bond in thes...
conditions have been developed for the palladium - catalyzed cross - coupling of 3-bromo-2,1-borazaronaphthalenes with potassium alkenyltrifluoroborates . twenty - seven alkenyl - substituted azaborines have been synthesized through this method , providing access to a family of 2,1-borazaronaphthalenes with a...
diabetes , a group of diseases of which type 2 diabetes is the most common , is a rapidly growing health problem worldwide ( 1,2 ) . type 2 diabetes is a progressive disease in which the advanced stages are characterized by micro- and macrovascular complications ( e.g. , retinopathy , nephropathy , and neuropathy ) a...
objectivethe status of psychosocial stress at work as a risk factor for type 2 diabetes is unclear because existing evidence is based on small studies and is subject to confounding by lifestyle factors , such as obesity and physical inactivity . this collaborative study examined whether stress at work , defined as j...
dynamic contrast - enhanced magnetic resonance imaging ( dce - mri ) is an important diagnosis tool of breast disease because of its good soft tissue resolution and time - signal intensity curve ; it has a higher sensitivity and often presents malignant breast nodules which are missed by physical examination , mammogra...
breast capillary hemangioma is a type of benign vascular tumor which is rarely seen . little is known about its presentation on dynamic contrast - enhanced magnetic resonance imaging ( dce - mri ) . here , we describe a case of suspicious breast lesion detected by dce - mri and pathologically confirmed as capillary...
in ophthalmologic practice , neodymium : yttrium - aluminum - garnet ( nd : yag ) laser is mainly applied for treatment of posterior capsular opacity.1 it has also been used for a variety of indications , including peripheral iridotomy,2 anterior vitreolysis,3 anterior capsule relaxing incisions,4 anterior capsulotomy ...
we report , to our best knowledge , the first case of treatment of pupil - occluding postoperative organized hyphema anterior to the intraocular lens ( iol ) using neodymium : yttrium - aluminum - garnet ( nd : yag ) laser . a 78-year - old asian female underwent uneventful cataract operation . she had been taking as...
dedicated research by numerous scientific groups into the causes and treatment of the human demyelinating disease multiple sclerosis ( ms ) , the most common disabling neurological condition of european , north american , and other temperate climates , has been ongoing for many decades . ms affects relatively...
multiple sclerosis ( ms ) is a chronic demyelinating disease of the human central nervous system ( cns ) . the condition predominantly affects young adults and is characterised by immunological and inflammatory changes in the periphery and cns that contribute to neurovascular disruption , haemopoietic cell in...
effective risk stratification is important for management of patients with acute myocardial infarction ( ami ) ( 1 , 2 ) . complete blood cell ( cbc ) is a simple , easily and widely performed laboratory test . among several cbc markers , the predictive value of white blood cell ( wbc ) and hemoglobin ( hb ) for sh...
the aim of this study was to assess the prognostic value of combined use of white blood cell ( wbc ) , hemoglobin ( hb ) , and platelet distribution width ( pdw ) in patients with acute myocardial infarction ( ami ) . this study included 1,332 consecutive patients with ami . patients were categorized into complete ...
the potential health and ecological effects of endocrine disrupting chemicals has become a high visibility environmental issue . the 1990s have witnessed a growing concern , both on the part of the scientific community and the public , that environmental chemicals may be causing widespread effects in humans and in a ...
a 61-year - old immunocompetent woman presented with a chronic headache for 10 months that had been progressively worsening for 18 days with emesis . the patient was a peasant with no particular exposure to avian ( especially pigeon ) feces or woodworking . the headache got worse , with several nonbloody , nonbilio...
central nervous system ( cns ) cryptococcosis is an opportunistic fungal infection that typically occurs in patients with reduced immunological function , such as patients with aids , patients receiving organ transplants , or patients receiving corticosteroid and immunosuppressive therapy . cns cryptococcosis rarely ...
lynx samples were collected as part of a large study assessing the health of the free - ranging lynx population in sweden from 1989 through 1999 and providing baseline data on diseases and parasites of the eurasian lynx . complete necropsy was performed on all animals shipped to the national veterinary institute , up...
cowpox virus , which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons , has reemerged in humans , domestic cats , and other animal species in europe . orthopoxvirus ( opv ) dna was detected in tissues ( lung , kidney , spleen ) in 24 ( 9% ) of 263 free - rangi...
between 1983 and 1989 , 1,441 subjects with type 1 diabetes were enrolled in the dcct . a total of 249 subjects were recruited as adolescents aged 1319 years : 32% were 1314 years old , 37% were 1516 years old , and 31% were 1719 years old . all adolescents had to be at least tanner stage ii in pubertal development...
objective the purpose of this study was to evaluate whether severe hypoglycemia or intensive therapy affects cognitive performance over time in a subgroup of patients who were aged 1319 years at entry in the diabetes control and complications trial ( dcct).research design and methods this was a longitudinal study inv...
there has been a remarkable increase in use of multidetector computed tomography ( mdct ) since its introduction . mdct has greater diagnostic capability and enables extended clinical applications , but it also has the potential to lead to an increase in radiation dose owing to the routine use of thinner sections , t...
purpose . to investigate the effect of low tube voltage ( 80 kv ) on image quality , radiation dose , and low - contrast detectability ( lcd ) at abdominal computed tomography ( ct ) . materials and methods . a phantom containing low - contrast objects was scanned with a ct scanner at 80 and 120 kv , with tube cu...
the patient , a 55-year - old man , sought treatment at a hospital in the southeast of scotland in april 2012 for nausea , vomiting , anorexia , jaundice , headache , and abdominal pain . at admission , the patient s blood sample was positive for anti - hev igm and igg and raised levels of alanine aminotransferase ( ...
we detected 2 hepatitis e virus ( hev ) strains in an acutely infected immunocompetent patient . two populations of genotype 3 virus were observed in the hypervariable regions and open reading frames 2 and 3 , indicating multiple infection with hepatitis e virus . persons with mixed infections may provide the oppor...
mediastinal abscess is a rare yet emergent infection of the thoracic cavity connective tissue , resulting from multiple potential sources : esophageal perforation ( boerhaave s syndrome ) , odontogenic and peritonsillar abscess ( descending necrotizing mediastinitis ) , cardiovascular or thoracic surgical procedures , ...
mediastinal abscess can be managed through a variety of both invasive and minimally invasive methods , as determined by location and spread of infection . thoracotomy remains the gold standard in treatment and is often employed . in the present case , a 54-year - old female with chronic pancreatitis presented with a ...
patient 1 , the index case - patient , was a 66-year - old tunisian man with a 4-year history of untreated diabetes mellitus . during march 20april 27 , 2013 , he visited his daughter ( patient 2 ) in qatar for 5 weeks ( figure 1 ) , 1 week of which they spent on a muslim pilgrimage to mecca , kingdom of saudi arabia...
in 2013 in tunisia , 3 persons in 1 family were infected with middle east respiratory syndrome coronavirus ( mers - cov ) . the index case - patient s respiratory tract samples were negative for mers - cov by reverse transcription pcr , but diagnosis was retrospectively confirmed by pcr of serum . sequences cluster...
we investigated 383 consecutive classical ptmc patients from the department of pathology , kangbuk samsung hospital , sungkyunkwan university school of medicine ( seoul , korea ) from january 1 , 2010 to december 31 , 2011 . the correlations between multifocality and clinicopathological characteristics including age ...
background : the clinicopathological characteristics and conclusive treatment modality for multifocal papillary thyroid microcarcinoma ( mptmc ) have not been fully established.methods:a retrospective study , systematic review , and meta - analysis were conducted to elucidate the clinicopathological significance of mpt...
focal osteoporotic bone marrow defect ( fobmd ) is a radiolucent area corresponding to the uncommon presence of hematopoietic tissue found in the jaws , usually at former extraction sites1,2 . radiographi - cally , it is localized , poorly demarcated radiolucency that varies in size , trabeculae , and border definiti...
focal osteoporotic bone marrow defect ( fobmd ) is a radiolucent area corresponding to the presence of hematopoietic tissue rarely found in the jaws . fobmd is most commonly located in the mandibular edentulous posterior area of a middle - aged female . from november 2011 to november 2012 , we experienced three cases...
with a prevalence of 1 in 5,000 , fragile x syndrome is the most common form of hereditary mental retardation . patients suffer from mild to severe mental retardation , mild facial dismorphologies and macroorchidism ( enlarged testicles ) . in addition , behavioral problems like autism and hyperactivity may be asso...
ten years after the identification of the gene responsible for fragile x syndrome , recent studies have revealed a list of mrnas bound by the fragile x gene product and have identified specific sequences required for the interaction between the fragile x protein and its targets . these results are a breakthrough in u...
a 55-year - old female patient presented with a four - month history of a continuous burning sensation of the oral mucosa . the patient had witnessed an accident and suffered from major depression 3 years prior to visiting our clinic . the patient had been on the following medication for 3 years : monoprolol 40 mg ...
burning mouth syndrome ( bms ) is defined as a chronic orofacial pain syndrome , without evidence of mucosal lesions and other clinical signs of disease or laboratory abnormalities . patients with bms complain of burning pain in the mouth , xerostomia and taste disturbances . it is more common among women and the m...
the international diabetes federation states that there are currently 316 million people with impaired glucose tolerance ( igt ) , which will increase to 471 million people by 2035 ( 1 ) . there is considerable debate as to whether these subjects should be considered to have a medical problem ( 2 ) . however , in s...
objectiveimpaired glucose tolerance ( igt ) through to type 2 diabetes is thought to confer a continuum of risk for neuropathy . identification of subjects at high risk of developing type 2 diabetes and , hence , worsening neuropathy would allow identification and risk stratification for more aggressive management.re...
human performance is affected by both the genetic makeup of the individual and the environmental factors . current research and interest in sports genetics focus on genetic variants that may make a significant contribution to the individual s performance . it is known that personal traits such as endurance , streng...
angiotensin-1 converting enzyme ( ace ) gene and -actinin-3 ( actn3 ) gene polymorphisms are considered to be the most important candidate genes for genetic predisposition to human athletic performance . in the present study , we aimed to analyze the distribution of ace and actn3 polymorphisms for the first time in m...
over the last decade , progress observed in sub - saharan african countries in increasing pmtct service coverage and in reducing new hiv infections among children is promising . for example , in the 21 global plan priority countries in sub - saharan africa , coverage of antiretroviral medicines for pregnant women liv...
about 69% of people living with hiv globally and over 90% of the children who acquired hiv infection are in sub - saharan africa . despite this , promising results have been observed , especially over the last decade for example , a 25% decline in new hiv infections as compared to 2001 and a 38% decline in the numbe...
various essential biological tasks that involve motion and mechanical work are performed by molecular motor proteins . the activity of these motors is modulated dynamically through complex biological pathways in response to environmental stimuli . allosteric regulation plays a key role in biological systems...
the rotational speed of an overcrowded alkene - based molecular rotary motor , having an integrated 4,5-diazafluorenyl coordination motif , can be regulated allosterically via the binding of metal ions . dft calculations have been used to predict the relative speed of rotation of three different ( i.e. , zi...
a 55-year - old man traveled to mainland china from march 5 to march 15 . by march 18 the patient was given a course of antimicrobial drugs , and the fever resolved . by march 23 , at this point , sars was suspected , and the patient was moved into isolation in an intensive care unit the same day and had to be intu...
with cases of severe acute respiratory syndrome ( sars ) occurring across geographic regions , data collection on the effectiveness of intervention strategies should be standardized to facilitate analysis . we propose a minimum dataset to capture data needed to examine the basic reproduction rate , case status and cr...
the histological features include the presence of newly formed blood vessels and the identifying feature of multinucleated giant cells . however , to date , there has been no molecular method of distinguishing the variants . surgical curettage showed high recurrence rate in case of aggressive lesions , so resection...
highlightscentral giant cell granuloma is considered one of the giant cell lesion affecting the oral cavity with variable histological forms ; may be aggressive or non-aggressive.many studies consider giant cell granuloma the same entity as giant cell tumor of long bones.different treatment modalities arise due to its ...
positron emission tomography ( pet ) is a procedure for evaluating biochemical and physiological processes by use of radiopharmaceuticals labeled with positron - emitting radionuclides . f - fluoro-2-deoxyglucose ( f - fdg ) pet scanning has been widely utilized for the diagnosis of various tumors ; for the staging a...
purposeto investigate the prevalence and clinical significance of incidental prostate fluoro-2-deoxyglucose ( fdg ) uptake and to evaluate its impact on patient management.materials and methodsof 47,109 men who underwent fdg positron emission tomography between 2004 and 2014 , 1,335 ( 2.83% ) demonstrated incidental fd...
although diagnosis of moderate to severe cases of glaucoma is relatively straightforward , with diagnoses confirmed based on the presence of typical visual field ( vf ) defects on standard automated perimetry ( sap ) and corresponding signs of glaucomatous onh damage , the disease typically remains asymptomatic in the ...
optical coherence tomography ( oct ) has established itself as the dominant imaging modality in the management of glaucoma and retinal diseases , providing high - resolution visualization of ocular microstructures and objective quantification of tissue thickness and change . this article reviews the history of oct im...
the control of dental biofilm is one of the cornerstones of preventive dentistry and can be achieved by mechanical means , use of chemical agents , or a combination of the two.1 mouth - washes are used as adjuvant agents in daily oral hygiene routine , aiding in the chemical control of dental biofilm . in brazil , most...
objectives : to evaluate in vitro the endogenous ph , titratable acidity and total soluble solid content ( tssc ) of mouthwashes available in the brazilian market.methods:the study sample was composed of 10 commercial brands of mouthwashes based on different active ingredients : cepacol , clinerize , equate , listerine...
metabolic syndrome affects a significant proportion of the population and is becoming increasingly more prevalent in adolescents [ 14 ] . the syndrome embodies many components including central obesity , insulin resistance , dyslipidemia , and hypertension [ 3 , 5 ] . in addition , the syndrome features a chronic l...
metabolic syndrome and t2d produce significant health and economic issues . many available animal models have monogenic leptin pathway mutations that are absent in the human population . development of the zdsd rat model was undertaken to produce a model that expresses polygenic obesity and diabetes with an intact le...
the 2013 aha / acc guideline on lifestyle management to reduce cardiovascular risk recommends a healthy dietary pattern with 5% to 6% of calories from sfa for lowering ldlc , a primary target for cvd risk reduction . both mufa and pufa the food sources of mufa in the mediterranean diet provide many micronutrients ...
backgroundavocados are a nutrientdense source of monounsaturated fatty acids ( mufa ) that can be used to replace saturated fatty acids ( sfa ) in a diet to lower low density lipoprotein cholesterol ( ldlc ) . wellcontrolled studies are lacking on the effect of avocado consumption on cardiovascular disease ( cvd ) ri...
in longitudinal clinical studies , where the change over time of an outcome is of interest , it is sometimes seen that the change is dependent on the initial value . the change over time may be significantly larger in subjects who had really higher ( or lower ) initial values as compared to subjects whose initial val...
background : part of the change over time of a response in longitudinal studies may be attributed to the re - gression to the mean . the component of change due to regression to the mean is more pronounced in the subjects with extreme initial values . das and mulder proposed a nonparametric approach to estimate the...
williams - campbell syndrome ( wcs ) is a rare congenital syndrome characterized by defective or completely absent bronchial wall cartilage in subsegmental bronchi , leading to distal airway collapse , producing a mechanical abnormality that may contribute to the formation of bronchiectasis distal to the collapsed bron...
williams - campbell syndrome is a rare congenital syndrome characterized by the absence of cartilage in subsegmental bronchi leading to formation of bronchiectasis distal to the affected bronchi . the differential diagnosis of bronchiectasis is broad and the rarity of the disease poses a diagnostic and management cha...
a neonatal intensive care unit ( nicu ) is a specially equipped nursery where critically ill and unstable infants receive diagnostic , therapeutic and life support care for a wide range of illnesses and conditions . a nicu is for those infants who are preterm , have low birth weight , or perinatal problems , or conge...
objective : to determine practice pattern of physiotherapists in the neonatal intensive care units ( icus ) in india with regards to cardiopulmonary and neuromuscular physiotherapy.materials and methods : a cross - sectional survey was conducted across india , in which 285 questionnaires were sent via e - mail to physi...
chordoid glioma of the third ventricle , a rare neuroepithelial tumor of the central nervous system , mostly originates from the anterior part of the third ventricle . chordoid glioma is classified as grade ii tumor according to 2007 world health organization ( who ) classification of brain tumors ( 1 ) . approxima...
chordoid glioma is a rare low grade tumor typically located in the third ventricle . although a chordoid glioma can arise from ventricle with tumor cells having features of ependymal differentiation , intraventricular dissemination has not been reported . here we report a case of a patient with third ventricular ch...
this work examines a simultaneous acquisition method for combined single photon emission computed tomography ( spect ) and x - ray computed tomography ( ct ) imaging systems . currently all commercially available spect - ct systems for preclinical imaging use a sequential scan mode that results in undesirably long ac...
multi - modality imaging provides coregistered pet - ct and spect - ct images ; however such multi - modality workflows usually consist of sequential scans from the individual imaging components for each modality . this typical workflow may result in long scan times limiting throughput of the imaging system . conve...
the incidence of renal infarction in an autopsy study was 1.4% , whereas clinical diagnosis was made in only 0.014% of the studied patients . the clinical manifestations of renal artery thrombosis vary , depending on whether the occlusion affects both renal arteries or not . delay of the correct diagnosis may prove d...
acute renal arterial thrombosis is a rare but very urgent situation demanding immediate treatment . it is characterized by unspecific symptomatology which often misleads the clinicians . as a result , precious time can be lost until the correct diagnosis is reached . the case of a 53-year - old female who underwe...
perineal hernias following abdomino - perineal excision of rectum ( aper ) , requiring repair , have been reported to occur in < 1% [ 1 , 2 ] of people . patients may exhibit some perineal bulging following an increase in intra - abdominal pressure , but are rarely symptomatic and , therefore , do not require operati...
symptomatic perineal hernias following abdomino - perineal excision of rectum have been reported to occur uncommonly . we present the case of a 79-year - old gentleman who developed a perineal hernia after laparoscopic - assisted extralevator abdomino - perineal excision ( elape ) of the rectum . despite initial myoc...
a 70-year - old japanese man presented at our hospital with an asymptomatic , 20 30 mm irregularly shaped blackish , flat elevated plaque with a gray nodule in the periphery on his left lower leg ( fig . the lesion had been present for 10 years and had recently enlarged , associated with bleeding . dermoscopy reve...
a 70-year - old japanese man presented at our hospital with an asymptomatic , blackish , irregularly shaped plaque with a gray nodule in the periphery on his left lower leg . the lesion had been present for 10 years and had recently enlarged , associated with bleeding . histopathologically , the tumor consisted of ...
neuropathic pain is a chronic condition caused by a primary lesion or dysfunction of the nervous system . the pain can be spontaneous , a painful response to innocuous stimuli ( allodynia ) , or an exaggerated pain in response to noxious stimuli ( hyperalgesia).1 approximately 65%85% of spinal cord injury ( sci ) pat...
objectivethe objective of this study was to examine the effectiveness of a novel nonpharmacological intervention breathing - controlled electrical stimulation ( breestim ) for neuropathic pain management in spinal cord injury ( sci ) patients.subjects and methodsthere were two experiments : 1 ) to compare the effect...
cilioretinal artery ( cra ) occlusions are rare in young patients . in these cases , the most commonly associated causes are considered to be the same as those implicated in central retina artery occlusions , such as vasculitic processes , migraine , cardiac disorder , and coagulation abnormality . the aim of this ...
backgroundcilioretinal artery ( cra ) occlusions are rare in young patients . in these cases , the most commonly associated causes are considered to be the same as those implicated in central retina artery occlusions , such as vasculitic processes , migraine , cardiac disorder , and coagulation abnormality . the ai...