Datasets:
ccdv
/
pubmed-summarization

Dataset card Data Studio Files
xet
 Community
8
article
stringlengths
0
826k
abstract
stringlengths
174
4.34k
polycystic ovarian morphology is displayed on ultrasound imaging in approximately 11.92.4 of women ( 1 ) . the most common features of pcos are hyperandrogenism , unovulation , infertility and weight gain . these women are at the risk of diabetes , atherosclerosis , and cardiovascular diseases ( 1 , 3 ) . since o...
backgroundthis study was designed to investigate the effect of metformin and flutamide alone or in combination with anthropometric indices and laboratory tests of obese / overweight pcos women under hypocaloric diet.methodsthis single blind clinical trial was performed on 120 pcos women . at the beginning , hypocalor...
oryzias latipes belongs to the order of beloniformes and adrianichthyidae , and is known to be distributed in japan , china , and korea . in south korea , oryzias latipes are often found in freshwater areas ( e.g. , nakdong - river as well as other rivers flow into the east sea ) yet they are also discovered around bra...
in order to monitor the developmental features of embryos , larvae , and juveniles of oryzias latipes ( temminck and schlegel ) , oryzias latipes was caught in river of shinduck - dong , yeosu - si , jeollanam - do , on may 2011 , and experiments were carried out in ichthyology laboratory at chonnam national university...
bilateral renal lymphoma frequently presents as an acute kidney injury ( aki ) 3 . with systematic chemotherapy for renal lymphoma however , in the case we describe herein , the patient 's kidney function greatly recovered after an open renal biopsy and before systematic chemotherapy . here , we review and discuss th...
key clinical messagerenal lymphoma as an initial lesion is relatively rare . bilateral renal lymphoma frequently presents as acute kidney injury . with systematic chemotherapy for the lymphoma , patients usually recover their kidney function . however , in the case we describe here , the patient 's kidney functio...
lipocortins are structurally related , glucocorticoid - inducible proteins that inhibit phospholipase a2 ( pla2 ) , thereby reducing the liberation of arachidonic acid from phospholipids and so limiting the synthesis of eicosanoid inflammatory mediators . this study is the first demonstration of one lipocortin , lipo...
vertebrate animals affiliate in multiple contexts , but sexual behavior is likely the only context of affiliation that is nearly ubiquitous across vertebrate species . thus , the various forms of social contact that we observe across species are subject to independent evolution in different taxa , although some forms...
species - typical patterns of grouping have profound impacts on many aspects of physiology and behavior . however , prior to our recent studies in estrildid finches , neural mechanisms that titrate species - typical group - size preferences , independent of other aspects of social organization ( e.g. , mating system an...
human identification is one of the most challenging tasks one has been confronted with whenever a catastrophe strikes . identification of the victims of the disaster is mandatory from a judicial point of view for settlement of wills , insurance payments and disposal of deceased estate as well as from a humanitarian p...
identification of individuals is the mainstay of any forensic investigation especially in cases of mass disasters when mutilated remains are brought for examination . dental examination helps in establishing the identity of an individual and thus , has played a vital role in forensic investigation process since long ...
brucellosis is a worldwide bacterial zoonosis posing hazards to the public health and causing economic losses for livestock production industry [ 13 ] . animal brucellosis is mainly characterized by reproductive involvement resulting in abortion and infertility , whereas human brucellosis is a febrile illness known a...
to determine the most prevalent biovar responsible for brucellosis in sheep and goat populations of iran , a cross - sectional study was carried out over 2 years in six provinces selected based on geography and disease prevalence . specimens obtained from referred aborted sheep and goat fetuses were cultured on bruce...
a 44-year - old woman developed intermittent exercise - induced headaches with chest tightness over a period of 10 months . cardiac catheterization followed by acetylcholine provocation demonstrated a right coronary artery spasm with chest tightness , headache , and ischemic effect of continuous electrocardiograph...
backgroundunder certain conditions , exertional headaches may reflect coronary ischemia.case reporta 44-year - old woman developed intermittent exercise - induced headaches with chest tightness over a period of 10 months . cardiac catheterization followed by acetylcholine provocation demonstrated a right coronary art...
noninvasive mechanical ventilation ( nimv ) refers to the application of artificial ventilation without an invasive access to the airway ( i.e. , without using an endotracheal or tracheostomy tube ) . the increased popularity of nimv among clinicians and researchers alike is justified by the fact that it spares the p...
background : noninvasive mechanical ventilation ( nimv ) is the delivery of positive pressure ventilation through an interface to upper airways without using the invasive airway . use of nimv is becoming common with the increasing recognition of its benefits.objectives:this study was done to evaluate the feasibility ...
stainless steel crowns are the most commonly used treatment modality for full - coverage restoration of primary molar teeth . american academy of pediatric dentistry recommends stainless steel crowns ( ssc ) treatment for cases with extensive and multi - surface caries . despite many advantages , the metal appearan...
objectives : this study aimed to compare the shear bond strength ( sbs ) of composite to stainless steel crowns ( ssc ) using two mechanical surface treatments ( msts ) and two bonding systems.materials and methods : eighty - four sscs were divided into six groups of 14 ; group1 : no mst+scotchbond universal adhesive (...
palisaded encapsulated neuroma ( pen ) is a benign neural tumor , which usually presents as small , solitary , asymptomatic , firm , skin - colored , or pink papule , or nodule , almost always present on the face or close to a mucocutaneous junction . palisaded encapsulated neuroma ( pen ) is a distinctive benign neu...
palisaded encapsulated neuroma ( pen ) is an infrequent benign cutaneous neural tumor , which usually presents as solitary , asymptomatic , papule or nodule , often localized on the faces , around the orifices , in middle age with no sex preponderance . rarely , it can be multiple . both solitary and multiple lesio...
myocardial function of the heart relies on rhythmic and effective cardiac contraction and relaxation , which depends on the appropriately timed generation and spread of cardiac electrical activity itself . at the cellular level , excitation - contraction ( e - c ) coupling is initiated by action potential depolarizat...
our work and others over the past few years have led to the identification of new roles of pak1 in cardiac physiology , such as the regulation of cardiac ion channel and actomyosin function . more recent studies have revealed that pak1-deficient mice were vulnerable to cardiac hypertrophy and readily progress to fail...
ankylosing spondylitis ( as ) is characterized by progressive ossification of the spinal column with resultant stiffness . as does not typically result in dysphagia as the syndesmophytes are marginal . dysphagia in the elderly is more commonly associated with diffuse idiopathic skeletal hyperostosis ( dish ) . we r...
we report the perioperative course of a patient with long standing ankylosing spondylitis with severe dysphagia due to large anterior cervical syndesmophytes at the level of the epiglottis . he was scheduled to undergo anterior cervical decompression and the surgical approach possibly precluded an elective pre - oper...
the clinical impact of coronary artery anomalies depends on the capability of anomalous arteries to provide adequate blood supply to the myocardium.[13 ] double left anterior descending coronary artery arising from the left and right coronary arteries is one of the rarest of coronary anomalies . it is usually clinica...
double left anterior descending coronary artery arising from the left and right coronary arteries is one of the rarest of coronary anomalies . in this report , we present a case of double left anterior descending coronary artery with one originating from the left main stem and the second one originating from the same o...
the scourge of cardiovascular diseases ( cvds ) is the most prevalent cause of death . according to national commission on macroeconomics and health ( ncmh ) , a government of india undertaking , there would be around 62 million patients with coronary artery disease ( cad ) by 2015 in india and of these , 23 million ...
background : hyperlipidemia is a major risk factor of coronary heart disease . currently available hypolipidemic drugs have been associated with number of side effects . arogyavardhini vati , an ayurvedic polyherbal formulation has been used for liver disorders . therefore , present study was designed to evaluate...
prosthetic joint infections ( pji ) are a serious complication associated with total knee replacement ( tka).1 fungal pji is a rare occurrence with few cases reported.123456 phelan et al . reported the first case of candidal pji in 1979.3 candida albicans is the most commonly isolated fungus.3 to the best of our know...
fungal prosthetic joint infection after total knee arthroplasty ( tka ) is a rare complication . lacunae exist in the management of this complication . 62 year old lady presented with pain and swelling in left knee and was diagnosed as candida tropicalis fungal infection after tka . she underwent debridement , re...
neonatal sepsis is a frequent complication of very low birth weight ( vlbw ) infants and it is an important cause of neonatal morbidity and mortality [ 1 , 2 ] . vlbw infants develop 2.7 times more sepsis than other infants since their immune system and skin barrier are immature and they are exposed to many invasive ...
the aim of this study is to identify risk factors for sepsis - related mortality in low birth weight ( < 1500 g ) infants . we performed retrospective cohort study to investigate risk factors for sepsis - related mort...
the term chronic periaortitis refers to a spectrum of idiopathic diseases characterized by a fibroinflammatory reaction that extends from the adventitia of the abdominal aorta and the common iliac arteries into the retroperitoneum . this often leads to the encasement of the adjacent structure , e.g. ureters or inferi...
a 73-year - old man with a history of hypertension and ascending aortic dissection was hospitalized for aggravated abdominal pain and general ache for 3 months . follow - up ct showed aggravated abdominal aortic hematoma with aneurysm , atherosclerotic periaortitis and bilateral hydronephrosis . an initial laborato...
skeletal muscle injury may result from toxin injection , crushing , freezing , and mechanical disruption induced by forceful stretches of muscle fibers . skeletal muscle fiber damage may also result from intense , unaccustomed , extreme ( i.e. , ultra - endurance events such as marathon running , triathlon , etc . ) ...
the study of exercise - induced muscle damage ( eimd ) is of paramount importance not only because it affects athletic performance but also because it is an excellent model to study the mechanisms governing muscle cachexia under various clinical conditions . although , a large number of studies have investigated eimd...
percutaneous nephrolithotomy ( pnl ) is a common treatment option for patients with renal stones . these emerge during initial puncture and lead to injuries in the surrounding organs ( e.g. , colon , pleural cavity , lung , spleen , liver , and duodenum ) ( 1 ) . though very rare , they may lead to morbidity in the...
objective the aim of this study was to investigate retrorenal colon incidence in percutaneous nephrolithotomy ( pnl ) interventions made in our clinic.materials and methods clinical data of 804 pnl patients , accumulated over a 7 year period ( 2006 - 2012 ) , was surveyed . the patient files were reviewed retrospecti...
the treatment of metastatic melanoma has been revolutionized in the last three years , with the fda registration of yervoy , a monoclonal antibody blocking lymphocyte regulatory receptor cytotoxic t lymphocyte - associated antigen 4 ( ctla-4 ) , and shortly afterward , the entry to the clinic of zelboraf , a small mole...
background . there is not yet an agreed adjuvant treatment for melanoma patients with american joint committee on cancer stages iii b and c. we report administration of an autologous melanoma vaccine to prevent disease recurrence . patients and methods . 126 patients received eight doses of irradiated autologous ...
the centers for disease control and prevention ( cdc ; atlanta , ga , usa ) has been performing passive surveillance for c. gattii in the united states since 2009 . isolates were collected as part of routine surveillance for c. gattii or submitted to the fungal reference laboratory at the cdc for identification . w...
cryptococcus gattii is a recognized pathogenic fungus along the pacific coast of the united states from california to washington . here we report that c. gattii may also be endemic to the southeastern united states and has probably been present there longer than in the pacific northwest .
all models with heterogeneities in the mechanical properties show large - scale patterns of stress maxima and minima when they are compressed . 1 . the nature of the patterns in stress and how the patterns are impacted by elastic heterogeneity 2 , which shows the equivalent von mises stress for four of the models ....
a new framework for thinking about the deformation behavior of rocks and other heterogeneous polycrystalline materials is proposed , based on understanding the patterns of stress transmission through these materials . here , using finite element models , i show that stress percolates through polycrystalline materials...
thirty crowns were produced to fit a model of a prepared central incisor ( tooth no . a deep chamfer finish line was used because this is recommended by most manufacturers of dental ceramics . the model was made as a natural tooth preparation with rounded edges and a finish line that curved apically on the buccal a...
comparison of fracture strength and fracture modes of different all - ceramic crown systems is not straightforward . established methods for reliable testing of all - ceramic crowns are not currently available . published in - vitro tests rarely simulate clinical failure modes and are therefore unsuited to distinguis...
genomic and metagenomic investigations have recently led to the delineation of a novel class of natural products called ribosomally synthesized and post - translationally modified peptides ( ripps ) . ripps are ubiquitous among living organisms and include pharmaceutically relevant compounds such as antibio...
there are various analgesic options like systemic opioids , neuraxial blocks , non steroidal anti inflammatory drugs ( nsaids ) , local infiltration , and so on ; however , in renal transplant patients systemic opioids are used with caution because of altered pharmacodynamics and opioid - related side effects . hence...
background and aims : transversus abdominis plane ( tap ) block is suitable for operations where parietal pain is a major cause of pain . renal transplant recipients are ideally suited to gain maximum benefit from tap block as the incision classically involves the lower abdomen . this study was conducted to evaluat...
throughout the world , the proportion of older people in the general population has increased in recent years . in addition to other general health issues there is a high level of tooth loss , dental caries , periodontal disease , xerostomia and cancer [ 1 , 2 ] . there are several studies on the dental status ...
in this study we describe the dental status and oral hygiene practices in institutionalized older people and identify factors associated with poor dental status . a cross - sectional study was performed in a nursing home in fortaleza , the capital of cear state ( northeast brazil ) . the number of decayed , missing...
the loss of gait ability after stroke becomes a lifetime disability in addition to social activity limitations . furthermore , the gait assessment must be reliable and valid to assess the gait disorder and treatment effects and establish a future treatment plan . however , few gait assessment tools have been ...
[ purpose ] this study aimed to examine the inter- and intra - rater reliability and validity of the modified functional ambulation category ( mfac ) scale . [ subjects and methods ] the participants were 66 stroke patients with hemiparalysis . the inter- and intra - rater validity of the mfac was calculated ...
though paraneoplastic pemphigus ( pnp ) and myasthenia gravis are rare , but can be associated with castleman 's disease . its association with various autoimmune diseases is well known and hence presentation can vary . this case report is an attempt to create awareness among us not to neglect a common symptom like o...
castleman 's disease is a rare autoimmune disorder with varied clinical presentations . castleman 's commonly involves mediastinum and hence it is thoracic in most of the reported cases . paraneoplastic pemphigus ( pnp ) and myasthenia gravis can be associated with multicentric castleman 's disease . its associat...
the benefits of a tracheostomy are generally accepted reduced risk of laryngeal injury , weaning from intermittent positive pressure ventilation ( ippv ) , less sedation , improved patient comfort , communication and oral hygiene and , although risks exist , they are thankfully rare . early tracheostomy may improve ...
three studies explore the case for tracheostomies in the intensive care unit ( icu ) . tracheostomies appear to have no effect on icu survival , according to a prospective observational cohort study that used a propensity score . in obese patients , surgical tracheostomies were associated with an increased risk of ...
uic 10339 was obtained from a sample collected from raven lake in northern wisconsin in august 2010 and cultured in z media . the lyophilized cells were extracted with ch2cl2 and meoh ( 1:1 ) and dried in vacuo . this extract showed antiproliferative activity against the human colon cancer cell line ht-29 and...
two new cyclic lipopeptides , trichormamides a ( 1 ) and b ( 2 ) , were isolated from the cultured freshwater cyanobacterium trichormus sp . uic 10339 . the strain was obtained from a sample collected in raven lake in northern wisconsin . the planar structures of trichormamides a ( 1 ) and b ( 2 ) were de...
future releases of tcsnp will integrate new t. cruzi sequences as they become available . many of these are expected to come from a resequencing effort that is underway in our lab . planned updates to the website functionality include the development of a standardized api and web services through which other database...
the tcsnp database ( http://snps.tcruzi.org ) integrates information on genetic variation ( polymorphisms and mutations ) for different stocks , strains and isolates of trypanosoma cruzi , the causative agent of chagas disease . the database incorporates sequences ( genes from the t. cruzi reference genome , mrnas , ...
tissue proteolytic enzymes are currently believed to be critical to the pathogenesis of panacinar emphysema . polymorphonuclear leukocytes ( polys ) have several enzymes including elastase and cathepsin g in their azurophil granules . they have collagenase in their specific granules . we have found that this coll...
fatty liver disease is a very common condition , with a prevalence of 2030% in the adult population and 70% in diabetes patients . among patients who develop non - alcoholic steatohepatitis ( nash ) , half will evolve to fibrosis , 1015% to cirrhosis and 5.4% to hepatic insufficiency . radiologists must report fa...
objectivefatty liver deposition is a very common finding , but it has many atypical patterns of distribution that can represent diagnostic pitfalls . the purpose of this pictorial essay is to review different patterns of fatty liver deposition and sparing.methodswe searched our archive retrospectively , reviewed the li...
the giant cell tumor , in which bcl-2 gene was expressed only in its malignant transformation , is a benign , primary skeletal neoplasm with variable biologic aggressiveness . the correlation between giant cell tumor in hereditary multiple exostosis is still not clearly determined . a 31-years - old female presente...
highlightsthe giant cell tumor is a benign , primary skeletal neoplasm with variable biologic aggressiveness.a coexistence with hereditary multiple exostosis with expression of ext-1 is very rare.bcl-2 gene is expressed only in malignant transformation of the giant cell tumor.the correlation between giant cell tumor an...
lymphangiomas are rare benign tumors that are preferentially located in the head and neck in children ( 1 ) . lymphangiomas in the peritoneal cavity are extremely rare occurring most commonly in the mesentery , followed by the omentum , mesocolon , and retroperitoneum . the etiology is unclear , but they are consid...
pain of the right iliac fossa in young girls can relate to several pathologies of the gastrointestinal and genitor - urinary tract . on the other hand , lymphangiomas in the peritoneal cavity are extremely rare . we report the case of a young woman with pain in the right iliac fossa caused by a cystic lymphangioma . ...
baseline sera samples of 1,400 mexican american persons enrolled in the san antonio family heart study ( 29 ) were screened for the presence of neutralizing antibodies to ad36 by serum neutralization assay as described . subsequently , seropositivity was evaluated for association with measures of adiposity available ...
objectivead36 , a human adenovirus , increases adiposity but improves glycemic control in animal models . similarly , natural ad36 infection is cross - sectionally associated with greater adiposity and better glycemic control in humans . this study compared longitudinal observations in indices of adiposity ( bmi and ...
traumatic injuries have a considerable impact on the population 's health in terms of mortality , morbidity and disability121 ) . trauma is the major cause of death for all age groups in most countries as well as in korea . approximately half of all trauma deaths are associated with head injury , and more than 60% ...
objectivethe aim of the present study is to estimate the incidence trend of head injury and the mortality based on traffic accident statistics and to investigate the impacts of rapid industrialization and economic growth on epidemiology of head injury in korea over the period 19702012 including both pre - industrialize...
the hypothalamus is thought to play an important role in migraine pathogenesis [ 14 ] . it is possible that periodic central disturbance of hypothalamic activity or labile threshold could account for the periodicity of the migraine attack . it also provides a mechanism by which emotional disturbances could be media...
substantial evidence points to melatonin as playing a role in the regulation of circadian rhythms , sleep , and headache disorders . the objective of the study was to assess 6-sulphatoxymelatonin ( amt6s ) levels in a large consecutive series of patients with migraine , comparing with controls . a total of 220 subj...
the visual system is specialized to extract features from complex natural scenes that have a unique statistical structure ( simoncelli and olshausen , 2001 ; felsen et al . , 2005a ) , including edges and contours that change in space and time across the field of view . although neurons in the primary visual cortex ...
summaryat eye opening , neurons in primary visual cortex ( v1 ) are selective for stimulus features , but circuits continue to refine in an experience - dependent manner for some weeks thereafter . how these changes contribute to the coding of visual features embedded in complex natural scenes remains unknown . here ...
we adopted tada ( for transmission and de novo association ) , a weighted , statistical model integrating de novo , transmitted and case - control variation . tada uses a bayesian gene - based likelihood model including per gene mutation rates , allele frequencies , and relative risks of particular classes of sequen...
summarythe genetic architecture of autism spectrum disorder involves the interplay of common and rare variation and their impact on hundreds of genes . using exome sequencing , analysis of rare coding variation in 3,871 autism cases and 9,937 ancestry - matched or parental controls implicates 22 autosomal genes at a ...
in july 2004 , an update of treatment guidelines for hypercholesterolemia was published by the national cholesterol education program adult treatment panel ( ncep - atp iii).1 this document reviews the results of the most recent clinical trials and assessed their implications for cholesterol management . therapeutic ...
rosuvastatin represents the latest inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a ( hmg - coa ) reductase introduced in clinical practice for the treatment of hypercholesterolemia . in comparative trials , across dose ranges this statin reduced low - density lipoprotein ( ldl ) cholesterol and total cholesterol s...
the chinese giant salamander ( a. davidianus ) belonging to one of the most primitive orders caudata , family cryptobranchidae , is the largest extant amphibian species in the world and found only in china , . it was called babyfish mainly lives in chinese interior water area . being crown as a living fossil fro...
next - generation technologies for determination of genomics and transcriptomics composition have a wide range of applications . andrias davidianus , has become an endangered amphibian species of salamander endemic in china . however , there is a lack of the molecular information . in this study , we obtained the...
hibernoma is a very rare fatty tumor that originates from remaining brown fat after one 's fetal stage . fetal brown tissue is known to be found from pelvic limb , scapular region , axilla , collum , abdominal etc . , and observed from a mass , gradually increasing in size . so far , there was hardly a case of a ma...
hibernoma is a very rare , benign soft fatty tumor that derived from remnants of fetal brown tissue . the following case of hibernoma break out occurred from a patient who had received surgical resection of neurilemmoma . there has never been a case that reported about hibernoma accompanied by neurilemmoma . it i...
neurologic development during infancy and childhood depends on physical health and genetic disposition , and progresses under the influence of the social context and environment1 . to perform activities in daily life , motor process and motor development is based on actions that a person enacts when interacting...
[ purpose ] the aim of this study was to investigate the influence of gender and family factors on performance in the fine motor domain of the denver ii developmental screening test . [ subjects and methods ] data were obtained from 2038 healthy children , 999 boys ( 49% ) and 1039 girls ( 51% ) in four age group...
in behet 's disease , coronary ostial stenosis following a bentall procedure is rarely reported but can be fatal.1 ) among chronic total occlusion ( cto ) lesions , the ostial location is especially difficult to treat with percutaneous coronary intervention ( pci ) due to the inability to engage the guiding catheter in...
we describe a case of chronic total occlusion of the right coronary artery ostium 5 months after a repeated bentall procedure in a patient with behet 's disease . in this patient , an antegrade approach to delivering the guidewire during percutaneous coronary intervention was not successful . coronary angiography r...
a 71-year - old woman presented with a swelling on her left upper eyelid in 2009 . she also had a small mass on her right upper eyelid that been present for the previous 3 years . she had a history of breast cancer occurring in 1991 , which was treated successfully without recurrence for 18 years . there was a si...
we report a case of muir - torre syndrome ( mts ) with a very rare combination of cancers , involving bilateral eyelid cancers and breast cancer . a 71-year - old female with a history of breast cancer from 18 years prior presented with bilateral eyelid tumors . one of her siblings had lung cancer , and another had...
a 4-year - old male neutered domestic shorthair cat was referred for investigation of jaundice . sequential serum biochemistry demonstrated increasing plasma bilirubin concentrations ; abdominal ultrasonography revealed ongoing pancreatitis and apparent extrahepatic obstruction of the common bile duct . exploratory...
case summarya 4-year - old male neutered domestic shorthair cat was referred for investigation of jaundice . the cat had a recent history of a skin laceration repair following trauma . sequential serum biochemistry demonstrated increasing plasma bilirubin concentrations ; abdominal ultrasonography revealed ongoing ...
posterior teeth , particularly maxillary premolars , have an anatomic shape that makes them more likely to fracture the cusps under occlusal load14 . additionally , these teeth when treated endodontically can be easily fractured because of pulp chamber roof removal19,20 , mainly when the marginal ridge is thin or tot...
objectives : this in vitro study evaluated the fracture resistance of weakened human premolars ( mod cavity preparation and pulp chamber roof removal ) restored with condensable resin composite with and without cusp coverage.material and methods : thirty human maxillary premolars were divided into three groups : group ...
it is associated with peptic ulcer disease ( pud ) , gastric / duodenal erosions , gastric adenocarcinoma , and gastric lymphoma both in healthy population and patients with uremia . studies have shown that pud is more prevalent in h.pylori positive hemodialysis patients than the general population . furthermore , ...
background the prevalence of peptic ulcer disease in hemodialysis patients is more than the general population . they are also more prone to complications including upper gastrointestinal bleeding . the aim of this study was to compare the efficacy of 14 days hybrid regimen with 14 days triple therapy for helic...
as a service to our authors and readers , this journal provides supporting information supplied by the authors . such materials are peer reviewed and may be reorganized for online delivery , but are not copyedited or typeset . technical support issues arising from supporting information ( other than missing files )...
abstractdeubiquitinating enzymes ( dubs ) are proteases that fulfill crucial roles in the ubiquitin ( ub ) system , by deconjugation of ub from its targets and disassembly of polyub chains . the specificity of a dub towards one of the polyub chain linkages largely determines the ultimate signaling function . we pre...
patients are often asymptomatic and the anomaly is discovered during imaging studies carried out for other reasons . however , when symptoms are present , they are related to hydro - nephrosis , infection , or calculus formation . the incidence of renal tumor in a horseshoe kidney is higher than in normal populatio...
renal cell carcinoma ( rcc ) is encountered in about 3% of all adult neoplasms . presence of any kidney malformation can change the plan for surgical treatment of rcc with organ preserving surgery . we report a case of clear cell rcc in a horseshoe kidney . computed tomography scan revealed a horseshoe kidney ano...
the von meyenburg complex ( vmc ) was first described in 1918 and is characterized by multiple bile duct hamartomas . these are benign developmental malformations composed of dilated intrahepatic bile ductules embedded in fibrous stroma . , the majority are discovered incidentally , but may present a diagnostic dil...
the von meyenburg complex ( vmc ) is an uncommon congenital malformation and is characterized by benign bile duct hamartomas . these are usually discovered incidentally and may represent a diagnostic dilemma when liver metastases are suspected . mri of vmc shows distinct imaging characteristics , but reporting of l...
in 2010 , approximately 15 million babies were born preterm worldwide , and more than one million died due to complications from preterm births ( ptb ) . however , a pathogen is identified in only one third of the cases , despite evidence of infection . obligate intracellular bacteria , which do not grow on media u...
waddlia chondrophila and chlamydia trachomatis are intracellular bacteria associated with human miscarriage . we investigated their role in human preterm birth . whereas presence of chlamydia trachomatis dna in genital tract was associated with human preterm birth , waddlia was not , despite being present in women 's...
its impact on the quality of life is similar to that of hypertension and diabetes and is more serious than that of depression . for these reasons although oab patients show many variable symptoms , the central symptom of oab is urgency , which is closely related to detrusor overactivity ( do ) during the filling phas...
purposewe investigated the effect of propiverine on cystometric parameters based on intraabdominal pressure ( iap ) in awake rats in an overactive bladder ( oab ) model induced by intravesical instillation of prostaglandin e2 ( pge2).materials and methodstwenty - two female sprague - dawley rats were used . polyethyl...
invasion is a most important and characteristic step in the complicated process of cancer cells . the blockage of these biological events by drugs or factors from food and natural resources will prolong the life span of an affected host . our previous research showed that green , oolong , and black tea extracts , t...
piceatannol is a stilbenoid , a metabolite of resveratrol found in red wine . piceatannol and sera from rats orally given piceatannol were found to dose - dependently suppress both the proliferation and invasion of ah109a hepatoma cells in culture . its antiproliferative effect was based on cell cycle arrest at low...
diabetes mellitus is a heterogeneous metabolic disorder characterized by altered carbohydrate , lipid and protein metabolism . the chronic hyperglycemia of diabetes is associated with long term damage , dysfunction and failure of various organs . in diabetic rats , however , complete cure of the disease has been el...
background : the study was undertaken to investigate the effect of 50% hydro -ethanolic leaf extracts of ruellia tuberosa l. and dipteracanthus patulus ( jacq . ) on lipid profile in alloxan induced diabetic rats.method:in lipid profile the parameters studied were serum total cholesterol , phospholipids , triglycerides...
in recent decades participation in long - distance endurance exercise events ( e.g. , ironman triathlons , ultra - marathons , and ultra - distance cycling events ) , has increased substantially among recreational exercisers and competitive athletes ( 7 , 17 , 34 ) . many of these events occur in extreme environmenta...
the purpose of this observational study was to determine the circulating leukocyte subset response to completing the 2013 hottern hell hundred recreational 164-km road cycle event in a hot and humid environmental condition . twenty - eight men and four women were included in this study . whole blood samples were ob...
inflammatory bowel diseases ( ibd ) are chronic immune - mediated conditions that are associated with a heavy personal and economic burden for patients and health care systems . ulcerative colitis ( uc ) and crohn s disease ( cd ) are the two main types of ibd . although their etiologies are unknown , some risk facto...
background : inflammatory bowel diseases ( ibd ) are a serious burden for both patients and health care providers because of the young age at which they occur and their chronic course.aim:the purpose of this study was to assess how general practitioners ( gps ) in the area of camerino - matelica , marche ( central ital...
osteoporosis is primarily a disease of older people and advancing age is one of the main determinants of osteoporosis and fragility fractures . the estimated lifetime risk of hip , spine , or distal forearm fracture for caucasian man at the age of 50 years is 20% and approximately 30% of all hip fractures occur in me...
introduction . the association of bone morphogenetic protein 2 ( bmp2 ) with bmd and risk of fracture was suggested by a recent linkage study , but subsequent studies have been contradictory . we report the results of a study of the relationship between bmp2 genotypes and bmd , annual change in bmd , and risk of fr...
research on stroke mechanisms reveals secondary injury develops through the inflammatory reaction induced by the leukocytes that adhere to the micro vessels during cerebral ischemia - reperfusion.9 ) this mechanism was verified in animal experiments using middle cerebral artery occlusion and reperfusion ( mcao - r ) mo...
objectivein this study , we investigate the role of adiponectin in the interaction between leukocytes and endothelium in the secondary inflammatory reaction of cerebral ischemia.methodsadiponectin knock - out mice group ( apn - ko ) ( n = 8) and wild - type mice group ( wt ) ( n = 8) were prepared . each group was su...
hiv testing and counselling ( htc ) is the cornerstone of treatment , care , and prevention [ 1 , 2 ] . it is particularly through htc that the ambitious goal of 90 , 90 , 90 ( 90% of all people living with hiv will know their hiv status ; 90% of all people with diagnosed hiv infection will receive sustained antiretr...
this systematic review aims to identify factors that facilitate or hinder the return for hiv test results . four electronic databases were searched . two independent reviewers selected eligible publications based on inclusion / exclusion criteria . quantitative studies published since 1985 were included . thirt...
evidence - based medicine ( ebm ) has been defined as the integration of best research evidence with clinical expertise and patient values . the first historical descriptions of ebm date back to the beginning of 1990s , when the work of gordon guyatt , david sackett and others established the emerging methodologies...
modern clinical practice relies on evidence - based medicine ( ebm ) and evidence - based guidelines ( ebgs ) . the critical evaluation of ebgs value is therefore an essential step to further improve clinical practice . in our opinion , correlating levels of evidence and grades of recommendation can be an easy tool...
oncogenes are mutated forms of cellular genes that are responsible for driving rampant cellular proliferation . however , the expression of an activated oncogene in normal human cells does not lead to their transformation , but to a permanent cell cycle arrest known as cellular senescence . hence , oncogene - induc...
work carried out primarily in the laboratory of fabrizio dadda di fagagna unveils the mitogenic properties of ras - induced reactive oxygen species ( ros ) and their relationship with the dna damage response . combined data from studies of cultured cells , zebrafish models , and clinical material consistently support...
today s children are valuable human resources for future ; and how they are raised today guarantees the quality of human resources in future ( 1 ) . in april 2005 , the world health organization ( who ) chose the motto let s care for all mothers and children s health , which implies the vast interest of nations as w...
background : growth retardation in children is a result of nutritional ignorance , inappropriate care , and inadequate monitoring of growth monitoring . this study was performed to assess the effect of mothers education program based on the precede model on the mean weight of children ( 6 - 12 months ) at health cent...
the most common cause of colo - vesical ( cv ) fistulae is diverticular disease , followed by malignancy and crohn 's disease . the preferred management of cv fistula is primary resection with anastomosis performed as a 1-stage procedure . however , there are reports of patients with cv fistula secondary to diverti...
introductioncolo - vesical ( cv ) fistulae are the most common type of fistulae associated with diverticular disease . surgery remains the mainstay of treatment , without which , cv fistulae rarely achieve complete healing.presentation of caseherein , we report the case of a 62-year - old man who developed a cv fistu...
hereditary multiple exostoses ( hme ) , also known as multiple osteochondroma ( mo ) , is an autosomal dominant bone disorder with an incidence of 1 in 50,000 live births in western populations ( 1 ) . the morbidity rate is greater in males than females , with a ratio of 1.5:1 , due to the mutations exerting a weaker p...
multiple osteochondromas ( mo ) , also known as hereditary multiple exostoses , is an autosomal dominant bone disorder . mutations in exostosin glycosyl transferase-1 ( ext1 ) and exostosin glycosyl transferase-2 ( ext2 ) , including missense , nonsense , frameshift and splice - site mutations , account for up to 80%...
tuberculous involvement of metacarpals and phalanges is a rare presentation of extrapulmonary tuberculosis in adult . tuberculous infection of the metacarpals , metatarsal and phalanges of hands and feet is known as tubercular dactylitis . a 65 years old female with history of pain and swelling at 1st metacarpal of...
introduction : tuberculous involvement of metacarpals and phalanges is a rare presentation of extrapulmonary tuberculosis in adult . tuberculous infection of the metacarpals , metatarsal and phalanges of hands and feet is known as tubercular dactylitis.case report : a 65 years old female with history of pain and swelli...
obesity is a major public health problem , with prevalence increasing at amazing rates in many countries . diagnosis of obesity and morbid obesity is based on determination of body mass index ( bmi ) , which is calculated as weight / height ( kg / m ) . the world health organization ( who ) defines underweight as a...
purpose . to investigate changes in optical coherence tomography parameters in morbidly obese patients who had undergone laparoscopic sleeve gastrectomy ( lsg ) . methods . a total of 41 eyes of 41 morbidly obese patients ( bmi 40 ) who had undergone lsg were included in study . the topographic optic disc parameters...
on the development of new probes , atsushi miyawaki ( riken ) described new generations of fluorescent proteins that allow the use of light to switch them reversibly between bright and dim fluorescent states ( protein highlighting ; ando et al . , 2004 ; dedecker et al . , 2006 ) , whereas gerard marriott ( univers...
a recent meeting entitled frontiers in live cell imaging was attended by more than 400 cell biologists , physicists , chemists , mathematicians , and engineers . unlike typical special topics meetings , which bring together investigators in a defined field primarily to review recent progress , the purpose of this meeti...
the chiropractic profession continues to grow in collective thinking and progress in defining care rendered . in so doing , the profession participates in the investigation of the types of care rendered and in the translation of research into practice . different types of care are developed from theories , clinical...
objectthe purpose of this article is to discuss a theoretical basis for wellness chiropractic manipulative care and to develop a hypothesis for further investigation.methodsa search of pubmed and of the manual , alternative , and natural therapy index system was performed with a combination of key words : chiropractic ...
periodontal diseases are infectious diseases of humans and other mammals that result in damage to the soft tissue and periodontal ligaments of the gingiva , resorption of alveolar bone from the jaw , and , ultimately , loss of teeth . it is becoming increasingly apparent that there is extensive interaction and cross ...
periodontal disease is one of the most common infectious diseases of humans . immune responses to infection trigger loss of alveolar bone from the jaw and eventual tooth loss . we investigated the contribution of b cell igd to alveolar bone loss by comparing the response of b cell normal balb / cj mice and igd ...
cardiovascular ( cv ) diseases are the leading cause of mortality in hemodialysis ( hd ) patients , accounting for nearly half of all deaths in this patient population . the cv mortality rate of hd patients is higher by a factor of ~10 than that of the general population , even after adjustment for age , race , gende...
backgroundgiven that cardiac disease is the leading cause of mortality in hemodialysis ( hd ) patients , identification of patients at risk for cardiac mortality is crucial . the aim of this study was to determine if positive t - wave amplitude in lead avr ( tavr ) was predictive of cardiovascular ( cv ) mortality an...
lupus vulgaris is the most common type of cutaneous tuberculosis , with most varied manifestations . it is a chronic and progressive form occurring in individuals with high degree of tuberculin sensitivity and moderate immunity . a characteristic feature of lupus vulgaris is its extremely chronic course with slow b...
cutaneous tuberculosis continues to be an important public health problem even with the availability of highly effective anti - tuberculous drugs . it constitutes 0.1% of all cases of extrapulmonary tuberculosis . lupus vulgaris is the most common form of cutaneous tuberculosis that occurs in previously sensitized ...
tumors of the pelvis are increasingly being irradiated for local treatment benefit , with the subsequent complication of anorectal injury . tumors inside the pelvic cavity are suited to receiving radiotherapy as the exposure to healthy tissue can be minimized and high doses can be delivered to the target tumor . ho...
post - radiation stricture is a rare complication after pelvis irradiation , but must be in the mind of the clinician evaluating a lower gastrointestinal obstruction . endoscopy has gained an important role in chronic radiation proctitis with several therapeutic options for management of intestinal strictures . the...
this supplement was made possible by the generous support of the american people through the support of the office of health , infectious diseases , and nutrition , bureau for global health , u.s . agency for international development ( usaid ) , under the terms of grant number ghag000600002 to the global alliance fo...
abstractthe few available studies of programme effectiveness in nutrition find that programmes are less effective than would be predicted from the efficacy trials that are the basis for evidencebased programming . some of these are due to gaps in utilisation within households . to a greater extent , these gaps can ...
functional and structural ( mri ) brain data for each animal were co - registered to a standard space based on an age - appropriate rhesus monkey brain template . whole - brain linear regression analyses examined the relations between fdg uptake and at . to account for potential confounds , age and sex gray matter ...
anxious temperament ( at ) in human and non - human primates is a trait - like phenotype evident early in life that is characterized by increased behavioural and physiological reactivity to mildly threatening stimuli 14 . studies in children demonstrate that at is an important risk factor for the later development of...
recently , transrectal color doppler sonography has been reported to be a very useful tool for measuring local blood flow in the female bovine reproductive tract . this technique allows estimation of the corpus luteum ( cl ) physiological status since blood flow on the cl parenchyma reflects its structural and functi...
the objective of this study was to investigate the effects of oxytocin infusion on corpus luteum ( cl ) function during early to mid - diestrus by measuring luteal size ( ls ) and luteal blood flow ( lbf ) along with plasma levels of progesterone ( p4 ) and prostaglandin metabolites ( 13,14-dihydro-15-keto - prostaglan...
congenital cataract is the leading cause of treatable blindness in children worldwide [ 13 ] . surgical management of congenital cataracts is a challenging task because of the elastic capsule , high pressure of the posterior chamber , and elevated inflammatory reaction due to irritation of the iris . in the mid-1970s...
purpose . to compare the surgical outcomes of limbal versus pars plana vitrectomy using the 23-gauge microincision system for removal of congenital cataracts with primary intraocular lens implantation . methods . we retrospectively reviewed all eyes that underwent cataract removal through limbal or pars plana incis...
fetal cholelithiasis is uncommon during pregnancy although its frequency of diagnosis has increased over the last years , probably due to both the improved accuracy and the increasing use of ultrasound examination in clinical practice.15 despite the remarkable number of fetal scans performed annually worldwide , little...
fetal gallstones and cholelithiasis , detected by routine third trimester ultrasound , have been described in the literature with controversial clinical significance . we report a case of fetal cholelithiasis detected at 35 weeks gestation during a routine scan . the diagnosis was performed using an integrated 2-di...
prostate biopsy has been widely performed in clinical practice in patients with high prostate - specific antigen ( psa ) levels , and the incidence of prostate cancer has increased . although a serum psa level of 3.0 or 4.0 ng / ml is used as a cutoff value for screening for prostate cancer , it is relatively difficu...
purposethis study was conducted to examine whether simultaneous transrectal prostate needle biopsy ( tpnb ) owing to an increase in prostate - specific antigen ( psa ) levels is safe and effective in patients who are scheduled for transurethral resection of the prostate ( turp ) for benign prostatic hyperplasia ( bph)....
maintaining fidelity of dna replication is essential to the survival of even the simplest organisms . based on mammalian models , lack of faithful dna replication by dna polymerases is associated with a large number of human diseases including , but not limited to , cancer and a variety of precancerous conditions ...
we discuss how the results of presteady - state and steady - state kinetic analysis of the polymerizing and excision activities of herpes simplex virus type 1 ( hsv-1 ) dna polymerase have led to a better understanding of the mechanisms controlling fidelity of this important model replication polymerase . despite a poo...
it has a special importance in health economics , and imposes higher costs on the health system compared to the other health system components ( 1 , 2 ) . hospitals are the main consumer of resources in any health sector thus ; improvement of their efficiency is the main way to decrease the hospital costs ( 3 ) . t...
abstractbackgroundthis study aimed to measure the hospital productivity using data envelopment analysis ( dea ) technique and malmquist indices.methodsthis is a cross sectional study in which the panel data were used in a 4 year period from 2007 to 2010 . the research was implemented in 12 teaching and non - teaching...
recently , a unique limbic encephalitis that predominantly affects young females and shows various manifestations , including initial psychosis , and subsequent central hypoventilation , intractable seizures , dysautonomia and prominent orofacial dyskinesia , has been noted [ 1 , 2 ] . in patients with this disorder ...
a 19-year - old man developed rapidly progressive muscle weakness and dysesthesia in the extremities , and dyspnea after a flu - like episode . nerve conduction studies showed reduced motor nerve conduction velocities with conduction block , and sensory nerve action potentials could not be evoked . the patient was ...
malignant lymphoma is the generic term given to tumors of the lymphoid system and these are divided into the following two major categories : hodgkin 's lymphoma and non - hodgkin 's lymphoma ( nhl ) . nhl usually involves lymph nodes but can also involve extra - nodal sites and can occur in the stomach , skin , lung...
non - hodgkin 's lymphoma ( nhl ) commonly presents as non - tender , enlarged lymph nodes , accompanied by diffuse symptoms of fatigue and low - grade intermittent fever and it is derived predominantly from the cells of the b lymphocyte series . nhl cases occur extra - nodally and in 3% of these cases the initial pr...
he narrated that when he was in second grade ( age 7 ) , he and a fellow student were irritating his neighbor in the classroom . the patient mentioned that the point broke off in his thigh and was never extracted . he complained that the site still hurt intermittently and after all this time , he wanted the lump an...
a pencil core with an intact pencil tip was excised from the thigh of a 60-year - old male 53 years after a puncture wound . histologic examination of the excised pencil core and the surrounding tissue revealed a foreign body reaction with abundant entrapped dark black pigment and chronic reparative changes , includi...
radiative transfer is unique among parameterization problems for global atmospheric models because the governing equations are deeply grounded in fundamental physics , the approximations ( e.g. , of onedimensional radiative transfer ) applicable across many relevant scales , and the result entirely deterministic . in a...
abstractthis article reports on the accuracy in aerosol and cloudfree conditions of the radiation parameterizations used in climate models . accuracy is assessed relative to observationally validated reference models for fluxes under presentday conditions and forcing ( flux changes ) from quadrupled concentrations of...
in the recent years , in response to the medical improvements , the field of infection control has progressed by cooperation of the epidemiology with health sciences to decrease risk factors for health care - associated infections ( hals ) ; therefore , interventions to prevent hals should be implemented . the primar...
background : despite the effectiveness of prophylactic antimicrobials to prevent surgical site infection the use of antibiotic prophylaxis is often inappropriate.objectives:the current study aimed to determine the pattern of prophylactic antibiotic use in a teaching hospital affiliated to jundishapur university of medi...
post - traumatic stress disorder ( ptsd ) represents arguably the most salient example of how fear and stress shape the mind . because controlled prospective studies can not be conducted on humans , it is necessary to use an animal model to help elucidate the etiology of ptsd and explore the associated neurological...
that the fear and stress of life - threatening experiences can leave an indelible trace on the brain is most clearly exemplified by post - traumatic stress disorder ( ptsd ) . many researchers studying the animal model of ptsd have adopted utilizing exposure to a predator as a life - threatening psychological stresso...
cataract is the leading cause of blindness in the world with blindness from cataract being particularly common in low - income countries . there are 39 million people reported to be blind worldwide.1 age - related cataract is responsible for 51% of world blindness , which represents about 20 million people.2 accordin...
aimto determine changes in post - cataract surgery central corneal thickness ( cct ) at lagos university teaching hospital by assessing the time it takes for the cornea to return to its preoperative thickness value.methodsthis study is a prospective , hospital - based open within - patient controlled study with the uno...
the european hedgehog ( erinaceus europaeus ) is one of the two species of hedgehogs living in catalonia ( north - eastern spain ) . in the area of study , this species is frequent in deciduous or semideciduous forests , in holm - oak woods and also in human - related habitats such as gardens , parks , and fields . due...
there are some reports about the risk of manipulating wild hedgehogs since they can be reservoirs of potential zoonotic agents like dermatophytes . the aim of this study was to describe the integument mycobiota , with special attention to dermatophytes of wild european hedgehogs . samples from spines and fur were c...
alterations in the six essential functions defining the neoplastic gene expression pattern collectively dictate malignant growth . escape , circumvention of programmed cell death , unlimited replicative potential , sustained angiogenesis , and local and metastatic invasiveness . targeted therapeutics currently bein...
cancer - cell survival , growth and metastatic potential are directed by dominant molecular signalling patterns , the components of which have been shown to be qualitatively different from their normal tissue counterparts . these signalling patterns can now be further distinguished by quantitative assessment , either...
isolation of different isolates of a. dactyloides was done with slight modification ( bandyopadhyay and singh , 2000 ) using the method described by duddington ( 1955 ) from different locations : varanasi , ghazipur , mirzapur , chunar ( uttar pradesh ) and ranchi ( jharkhand ) , india . different isolates were purif...
application of fertilizers such as urea , diammonium phosphate ( dap ) and muriate of potash in soil adversely affected the spore germination of arthrobotrys dactyloides . amendment of soil with urea at the concentrations of 1.0% , 0.5% and 0.1% completely inhibited spore germination and direct trap formation on the ...
glycemia and diabetes are rising globally accounting 347 million people worldwide . the study of type 2 diabetes ( t2d ) has been stimulated due to its growing pandemic and intricate physiopathology , in search of better ways of prevention and treatment of the t2d and its associated complications . among the several st...
aim . chronic diseases are the leading cause of death worldwide . advanced glycation end products , known as ages , are a major risk factor for diabetes onset and maintenance . methylglyoxal ( mg ) , a highly reactive metabolite of glucose , is a precursor for the generation of endogenous ages . methods . in th...
previous studies focused on retraining muscle coordination patterns in which the optimal ratios between the gluteus maximus ( gm ) and the erector spinae ( es ) are assumed to be essential1,2,3 . bridging exercises are associated with a risk of dominant hamstring ( ham ) and es activities as compensation for gm...
[ purpose ] the purpose of this study was to investigate activities of the hip extensors and erector spinae during bridging exercise by using instruments with a laser pointer on the pelvic belt . [ subjects ] twelve subjects ( age , 23 to 33 years ) with non - specific low back pain volunteered for this study ...
muscular dystrophies with an autosomal recessive mode of inheritance comprise of a genetically heterogeneous group of disorders . among these , miyoshi myopathy ( mm ) is an early - adult onset , autosomal recessive form of distal muscular dystrophy , characterized by predominant involvement in the calf muscles and h...
miyoshi myopathy ( mm ) is an autosomal recessive distal muscular dystrophy caused by mutations in the dysferlin gene ( dysf ) on chromosome 2p13 . although mm patients and their mutations in the dysf gene have been found from all over the world , there is only one report of genetically confirmed case of mm in korea ...
pancreatic islet transplantation is a physiologically advantageous and minimally invasive procedure for the treatment of type 1 diabetes mellitus ( 1 ) . the success rate of islet transplantation has been improved by transplanting a higher mean islet mass prepared from two to four donor pancreases and using glucoc...
pancreatic islet transplantation is a physiologically advantageous and minimally invasive procedure for the treatment of type 1 diabetes mellitus . here , we describe the first reported case of successful allogeneic islet transplantation alone , using single - donor , marginal - dose islets in a korean patient . a ...
behavioral and neurophysiological data were collected from two exotropic juvenile rhesus ( macaca mulatta ) monkeys ( 6 years , 910 kg ) . strabismus was previously induced by optical prism - rearing of infant monkeys . during the prism - rearing paradigm , infant monkeys wore a helmet like device that housed a hor...
purposestrabismus correction surgery is well documented in both the literature and practice with varying levels of success and permanence . our goal was to characterize longitudinal changes in eye alignment and eye movements following strabismus correction surgery in a monkey model for developmental strabismus.method...
diabetes of long duration results in irreversible functional and structural damage leading to several complications . diabetes is often associated with severe periodontal disease and is considered a risk factor for periodontal disease progression . analysis of the national health and nutrition examination survey ( ...
introduction : the role of serum monocyte chemoattractant protein-1 ( mcp-1 ) as a biomarker of periodontitis is well documented ; however , its role in diabetic patients with periodontitis is unknown.aim:this study was conducted to determine the presence and concentration of serum mcp-1 in diabetic patients with and w...
genome - scale transcriptional regulatory network ( trn ) for any specific microbial organism is a critical component on the way to the next big milestone in system biology building an integrated metabolic and regulatory model that can accurately predict cellular growth phenotypes . several approaches and associated...
web services application programming interface ( api ) was developed to provide a programmatic access to the regulatory interactions accumulated in the regprecise database ( http://regprecise.lbl.gov ) , a core resource on transcriptional regulation for the microbial domain of the department of energy ( doe ) systems b...