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we studied cation exchange ( ce ) in
core / shell cu2xse / cu2xs nanorods
with two cations , ag+ and hg2 + , which are known
to induce rapid exchange within metal chalcogenide nanocrystals ( ncs )
at room temperature . at the initial stage of the reaction , the guest
ions diffused through the cu2xs shell and ... | |
despite attempts to increase the number of potential kidney donors , there continues to be a significant shortage of kidneys available to meet the demand for renal transplantation .
the gap between the number of patients waiting for a kidney transplant and the number of patients receiving a transplant has widened ove... | background .
recipients of laparoscopically procured kidneys have been reported to have delayed graft function , a slower creatinine nadir , and potential significant complications .
as the technique has evolved laparoscopic donor nephrectomy technique is becoming the gold standard for living donation .
study des... |
asphalt modification is a common practice since the last two decades throughout the united states of america ( usa ) .
asphalt modification with synthetic and natural polymers is not a new concept in this industry , as one can find traces of modification back in 1843 .
synthetic rubber ( neoprene ) was used for asp... | asphalt has been modified for the past several decades using various additives , including synthetic polymers .
polymer modification improves structural and engineering characteristics of the binder , which is a result of improvement in rheological characteristics of binder as well as its adhesion capability with the... |
traumatic injuries to the spinal cord frequently leave permanent neurological disabilities to the victims and impose enormous economic burdens on the families and society , yet there is no single effective therapeutic option to improve functional recovery .
recent studies have shown promises that cellular replacement... | the molecular microenvironment of the injured spinal cord does not support survival and differentiation of either grafted or endogenous nscs , restricting the effectiveness of the nsc - based cell replacement strategy . studying the biology of nscs in in vivo
usually requires a considerable amount of time and cost , ... |
sexually undifferentiated juvenile sea bass ( approximately 1 year of age ) were obtained from coelho & castro lda .
( pvoa do varzim , portugal ) and were kept in 2,000-l glass fiber tanks ( density , 24 kg / m ) supplied with natural sea - water ( 20 1 ) until exposures began .
fish used for studies had an avera... | backgroundthe potential impact of natural and synthetic estrogens on aquatic ecosystems has attracted considerable attention because it is currently accepted that their joint effects are more severe when they are present in mixtures .
although it is well - known that they occur as mixtures in the marine environment ,... |
the basic reproduction number r0 of an infectious agent is defined as the expected number of secondary cases caused by one typical infected individual in a population consisting of susceptibles only .
when an outbreak has started and the approximation that the population is fully susceptible no longer holds , one gen... | we investigate the merit of deriving an estimate of the basic reproduction number \documentclass[12pt]{minimal }
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... |
developmental dyslexia is a neurological condition characterized by difficulties in reading - related tasks such as word recognition and spelling in spite of normal intelligence , adequate education and motivation to read proficiently ( lyon et al . , 2003 ) .
( 2012 ) for meta - analyses ] have identified abnormalit... | abnormalities in cortical structure are commonly observed in children with dyslexia in key regions of the reading network .
whether alteration in cortical features reflects pathology inherent to dyslexia or environmental influence ( e.g. , impoverished reading experience ) remains unclear . to address this question ... |
cancer occurrence is highly influenced by environment , genetic , gender , age , race , socioeconomic status , education , culture , obesity , and all life style related factors which might result in incidence rate change of these cancers in every population ( 1 , 2 ) . main gynecologic cancers ( ovary , endometrium an... | abstractbackgroundfemale cancer , especially breast and gynecologic cancers are considered multistage disease , highly influenced by risk and protective factors and/or screening preventive modalities .
consequences of all these factors result in the trend of change over time.methodsin this comparative study , based o... |
traumatic duodenal injuries with significant tissue loss are rarely seen but are a potentially challenging problem when they occur in either children or adults [ 1 - 3 ] .
the incidence of duodenal injury in the literature ranges from 3.7% to 5.0% and it is often accompanied by other abdominal injuries because of its... | abdominal wall defect with large duodenal disruption after penetrating abdominal injury is a rare emergency situation that can result in life - threatening complications .
we report on a 64-year - old man who had abdominal wall defect with large duodenal disruption after penetrating abdominal injury .
the patient p... |
huntington 's disease ( hd ) is an adult - onset autosomal - dominant inherited neurodegenerative disorder with progressive symptoms that include involuntary movements , cognitive deficits , and various psychiatric disturbances [ 13 ] .
hd is caused by an expanded cag repeat in the huntingtin gene [ 46 ] .
... | currently , there is no effective treatment for the marked neuronal loss caused by neurodegenerative diseases , such as huntington 's disease ( hd ) or ischemic stroke .
however , recent studies have shown that new neurons are continuously generated by endogenous neural stem cells in the subventricular zone ( svz ) o... |
n bond in
an aromatic system results in azaborines , heterocycles that retain
most of the aromatic character and thermal stability associated with
their c = c analogues .
n bond desymmetrizes the heterocycle , allowing functionalization
at various positions around the ring with complete regiochemical control ... | despite
their potential applications in both medicinal chemistry
and materials science , there have been limited reports on the functionalization
of 2,1-borazaronaphthalenes since their discovery in 1959 . to access
new chemical space and build molecular complexity , the suzuki
miyaura
cross - coupling of b... |
in june 2001 , five persons with a febrile respiratory illness visited a community hospital .
the patients were among 15 persons ( age range 1961 years ; median 38 years ) , residents of four states , who had participated in a geology - biology community college class trip to nicaragua . to determine the cause and de... | we investigated an outbreak of unexpectedly severe histoplasmosis among 14 healthy adventure travelers from the united states who visited a bat - infested cave in nicaragua .
although histoplasmosis has rarely been reported to cause serious illness among travelers , this outbreak demonstrates that cases may be severe... |
atherosclerotic coronary artery disease ( cad ) has long been shown to involve inflammatory processes .
numerous pathways and markers have been studied in order to detect the presence and evolution of this disease .
the role of various biological inflammatory markers as risk factors and prognosticators has been elu... | background : atherosclerotic coronary artery disease ( cad ) has long been shown to involve chronic low - grade subclinical inflammation . however , whether there is association between hematological indices assessed by complete blood count ( cbc ) and coronary atherosclerotic burden has not been well studied.materials... |
the field of cancer chemotherapy has been developed enormously during the past fifty years . prior to 1969 ,
however , the arsenal of chemotherapeutic agents was devoid of compounds which are inorganic in nature because of generally accepted belief that most metals and their compounds were potentially carcinogenic . ... | reaction(s ) of 5-guanosine monophosphate ( 5gmp ) with di- and triorganotin(iv ) chloride(s ) led to formation of organotin(iv ) derivatives of general formulae , [ r2sn(5-gmp)h2o]n and [ ( r3sn)2(5-gmp)h2o]n , where r = me , n - bu , and ph ; r = me , i - pr , n - bu , and ph ; ( 5-gmp)2 = 5-guanosine monophospha... |
platelet - rich plasma ( prp ) is a platelet concentrate in a small plasma volume .
these proteins are capable of enhancing cell adhesion and act like a matrix for the formation of bone , connective tissue and epithelium.1 platelets contain growth factors in their alfa granules , such as platelet - derived growth fac... | objectives : the purpose of this study was to compare the quantity and quality of platelets in platelet - rich plasma ( prp ) samples prepared using either the single- or the double - centrifugation protocol.methods:ten adult white new zealand rabbits were used .
ten ml of blood were drawn from each animal via cardia... |
thoracolumbar penetrating spinal cord injury ( sci ) often produces motor and sensory alterations in hindlimbs . promising pharmacological treatments and treadmill locomotion training
are used for inducing restoration of locomotion and spinal reflexes after contusive , compressive lesions or by a penetrating sci [ 24... | we performed experiments in cats with a spinal cord penetrating hemisection at t13-l1 level , with and without tamoxifen treatment .
the results showed that the numbers of the ipsilateral and contralateral ventral horn neurons were reduced to less than half in the nontreated animals compared with the treated ones .
... |
despite routine screening and advances in treatment , retinopathy of prematurity ( rop ) remains a major cause of vision loss in children .
it is estimated that 14,00016,000 preterm infants in the usa are affected by some degree of rop each year , and the rate of rop is increasing worldwide .
this disease entity is... | preterm infants with retinopathy of prematurity are at increased risk of poor neurodevelopmental outcomes . because the neurosensory retina is an extension of the central nervous system , anatomic abnormalities in the anterior visual pathway often relate to system and central nervous system health .
we describe optic... |
in recent years , as cesarean sections themselves have become more common , more and more delivery rooms have allowed husbands / partners to be present during a cesarean section , arguing that this reduces the mother 's anxiety , cements the father 's role in childrearing , and reflects current occupational positions o... | objective . in recent years
, more and more delivery rooms have allowed husbands / partners to be present during a cesarean section nonetheless , many still oppose the idea .
the study is designed to investigate the attitudes of israeli gynecologists , anesthetists , operating - room nurses , and midwives on this i... |
lafora disease is a form of progressive myoclonic epilepsy with autosomal recessive transmission .
two genes have been identified so far : epm2a and nhlrc1 , and a third gene , concerning a pediatric onset subform , has been recently proposed .
we report the case of a 23-year - old woman of turkish origin with an u... | |
the management of high - risk surgical patients ( hrsp ) presents a huge challenge to anesthetist as a perioperative physician .
often , there is a need to balance on one hand the provision of a good anesthesia that prevents undue stimulation of sympathetic responses / reflexes and then tilting the already deranged h... | background : hemodynamic monitoring ( hm ) and optimization of cardiac output and parameters of dynamic fluid responsiveness is said to improve perioperative outcome in high - risk surgical patients ( hrsp ) .
there is insufficient data to determine the burden of care and hm practices in hrsp in nigeria .
hence , t... |
autism spectrum disorders ( asd ) , according to the diagnostic and statistical manual of mental disorders 5 edition ( dsm-5 ) , are neurodevelopmental pathologies impairing both social competencies and patterns of behavior . until today
it is probably also for this reason that in the last decades complementary and a... | one of the most commonly used complementary and alternative practices in children with autism spectrum disorder ( asd ) is the supplementation of omega-3 .
we describe the case of a child with asd who seemed to respond to omega-3 supplementation in a relevant and lasting manner .
so far , based on the results of ra... |
exposure to asbestos fibres has been shown to cause asbestosis , pleural diseases such as pleural plaques , lung cancer , malignant mesothelioma and some other types of cancers [ 13 ] .
one of the most frequent diseases caused by inhalation of asbestos is asbestosis , an interstitial pulmonary process that slowly dev... | manganese and extracellular superoxide dismutases ( sod2 and sod3 ) are part of the enzymatic defence against reactive oxygen species , which are involved in the pathogenesis of asbestosis .
this study investigates whether sod2ala 9val and sod3 arg213gly genetic polymorphisms represent risk factors for asbestosis in... |
many internet vendors including amazon , google , and microsoft have introduced various cloud solutions to provide computing resources , programming environments , and software as services in a pay - as - you - go manner .
for example , amazon introduces amazon elastic compute cloud ( ec2 ) which provides computing c... | now , the security of digital images is considered more and more essential and fingerprint plays the main role in the world of image .
furthermore , fingerprint recognition is a scheme of biometric verification that applies pattern recognition techniques depending on image of fingerprint individually . in the cloud e... |
the back squat ( bs ) is a fundamental exercise prescribed for both athletes and non - athletes for developing lower - body strength .
the resulting leg , hip , and back strength from the prescription of systematic squat resistance training reportedly improves athletic performance when included in a training program ... | muscular activity , vertical displacement and ground reaction forces of back squats ( bs ) , rear - leg elevated split squats ( rless ) and split squats ( ss ) were examined .
nine resistance - trained men reported for two sessions .
the first session consisted of the consent process , practice , and bs 1-repetitio... |
genitourinary tuberculosis ( tb ) is the second most common extrapulmonary form of tb after lymphadenopathy .
genitourinary tb accounts for 27% ( range 1441% ) of nonpulmonary cases and is usually a late complication of pulmonary tb .
renal damage due to caseous destruction of renal parenchyma or obstructive uropat... | granulomatous interstitial nephritis ( gin ) is a rare manifestation of renal tuberculosis ( tb ) .
we report a case of rapidly progressive renal failure ( rprf ) , granulomatous inflammation of cervical lymph node and gin as presenting manifestations of tb .
aspiration cytology of cervical lymph node showed granul... |
the population impact of arterial hypertension ( aht ) consists in its high prevalence and in the strength of its risk ratio with cardiovascular pathologic conditions .
more than a quarter of the world adult population is already hypertensive and this number is projected to increase to 1,56 billion people by 2025 .
... | east european countries have reported high prevalence of arterial hypertension ( aht ) . in order to investigate the data for romania
, we firstly performed a national survey the study for the evaluation of prevalence of hypertension and cardiovascular risk in adult population in romania ( sephar ) .
a representat... |
the high - density lipoprotein cholesterol ( hdl - c ) is a group of heterogeneous lipoproteins that are involved in the transport of sterols and lipids .
guidelines for management of patients with dyslipidemia primarily focus on achievement of target low - density lipoprotein cholesterol ( ldl - c ) levels for coron... | the high - density lipoprotein cholesterol ( hdl - c ) is considered anti - atherogenic good cholesterol .
it is involved in reverse transport of lipids .
epidemiological studies have found inverse relationship of hdl - c and coronary heart disease ( chd ) risk . when grouped according to hdl - c , subjects having ... |
venovenous extracorporeal membrane oxygenation ( vv ecmo ) has been well described to manage acute respiratory distress syndrome ( ards ) .
the onset of ards in the setting of h1n1 influenza is often hyper - acute , requiring emergent ventilatory support and , in severe cases , ecmo cannulation . in the setting of em... | tracheal injury is a rare but highly morbid complication of endotracheal intubation .
recent reviews have advocated conservative management of these injuries without operative intervention .
extracorporeal membrane oxygenation may be a useful tool in non - operative management of tracheal injury in the setting of s... |
mirizzi syndrome , first described in 1948 , is where there is repeated inflammation of the gallbladder from a gallstone impacted in either the cystic duct or gallbladder neck .
this leads to the formation of adhesions from the gallbladder to the common bile duct resulting in anatomic distortion of these structures .... | mirizzi syndrome type ii is an uncommon cause of obstructive jaundice caused by an inflammatory response to an impacted gallstone in hartmann 's pouch or the cystic duct with a resultant cholecystocholedochal fistula .
two cases of mirizzi syndrome type ii are presented .
clinically only one patient had jaundice an... |
mir132 is a creb induced microrna involved in dendritic spine plasticity .
we observed that visual experience regulates histone post - translational modifications at a cre locus important for mir212/132 cluster transcription and mir132 expression in the visual cortex of juvenile mice .
monocular deprivation reduced... | |
sleeve cages were constructed in two sizes , 10 by 40 cm and 60 by 100 cm , from standard white polyester voile ( hancock fabrics , lexington , ky ) and from white nylon mesh ( 70 m thread diameter and 161 m mesh opening , dynamesh , west chicago , il ) sewn on three sides using polyester thread to form a bag .
f... | sleeve cages for enclosing or excluding arthropods are essential components of field studies evaluating trophic interactions .
microclimatic variation in sleeve cages was evaluated to characterize its potential effects on subsequent long - term experiments .
two sleeve cage materials , polyester and nylon , and two... |
type 1 diabetes mellitus ( t1 dm ) is the most common endocrine - metabolic disorder of childhood and adolescence that has important consequences for physical and emotional development .
appropriate management of the disease and maintenance of blood glucose level in the normal range could reduce the rate of complicat... | background : an association of eating disorder with diabetes mellitus may lead to a serious lack of metabolic control , higher mortality and morbidity .
there is no recent study conducted in the iranian population about eating disorder and its variants .
the aim of the present study is investigation of frequency of... |
spinal meningocele is associated with spina bifida cysts and may occur at any age . however
, intrapelvic meningocele is rare and , without spinal compression , this type of meningocele does not cause any discomfort . for this reason , intrapelvic meningocele has not attracted much attention for a long time . here
... | asymptomatic intrapelvic meningocele is rare . here , we report the case of a 30-year - old chinese man who underwent sigmoidectomy due to megacolon . during the operation ,
an intrapelvic cyst was found and resected .
meningocele was confirmed by histological examination .
the patient recovered well postoperativ... |
spontaneous intracranial hypotension ( sih ) is an uncommon cause of sudden and persistent headache and patients typically present with postural or exertional headaches that can be temporarily relieved by lying in a supine or recumbent position .
associated symptoms are common , among which there are cranial nerve pa... | spontaneous intracranial hypotension is an uncommon cause of sudden and persistent headache : associated symptoms are common , among which there are cranial nerve palsies , especially of the abducens nerve .
we report a case of a 21-year - old man with a transient and isolated third nerve palsy due to spontaneous int... |
a 52-year - old healthy man presented with intermittent ocular pain of indistinct duration in his right eye .
his best - corrected visual acuity ( bcva ) was 20/20 , and the intraocular pressure in the right eye was 10 mmhg .
slit - lamp and gonioscopic examination of the right eye showed an irregularly - shaped pi... | we report a case of ciliary body melanocytoma in a korean patient , which presented as an intermittently painful pigmented iris mass and was successfully managed by iridocyclectomy . a 52-year - old healthy man presented with an irregularly - shaped and heavily - pigmented mass at the iris root of his right eye .
vis... |
tobacco use is among the most prevalent ,
albeit preventable , human
carcinogen exposures .
cigarette smoking causes up to 90% of lung cancer ,
the most common cause of cancer death in the united states , resulting
in a projected 159,480 deaths in 2013 .
tobacco - specific
nitrosamines ( tsna ) are among ... | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
( nnk , 1 ) is a potent tobacco - specific lung carcinogen
believed to play a
key role in the development of lung cancer in smokers .
metabolic activation
of nnk to dna damaging reactive intermediates proceeds via -hydroxylation
pathways .
the end products of... |
diabetes is a growing epidemic affecting more than 346 million people worldwide ( 13 ) .
the metabolic abnormalities associated with diabetes lead to altered platelet , endothelial cell , and smooth muscle cell function ( 47 ) .
together , these changes promote systemic atherosclerosis and lead to the traditional m... | objectivethe aim of this study was to investigate the relationship between diabetes and different phenotypes of peripheral vascular disease ( lower extremity peripheral artery disease [ pad ] , carotid artery stenosis [ cas ] , and abdominal aortic aneurysm [ aaa]).research design and methodsprevalence of vascular dise... |
nonunion of a fracture can pose a significant challenge in terms of skeletal stability , soft tissue biomechanics and potential limb loss .
they most commonly occur as a consequence of infection , mal - alignment , metabolic and endocrine abnormalities .
however , in otherwise healthy young individuals , such etiol... | pseudoaneurysm of the posterior tibial artery ( pta ) is uncommon , and they mainly occur following high - velocity trauma , open fractures and can be iatrogenic in nature . to the best of our knowledge ,
this is the first reported and successfully treated case of pta pseudoaneurysm identified as a consequence of tib... |
patients were selected for inclusion in this study from different cohorts tested on either family - based wes , targeted resequencing or high - resolution melting analysis ( table 1 ) .
clinical evaluation was performed by at least one expert clinical geneticist . written informed consent for inclusion in the study
... | despite a high heritability , a genetic diagnosis can only be established in a minority of patients with autism spectrum disorder ( asd ) , characterized by persistent deficits in social communication and interaction and restricted , repetitive patterns of behavior , interests or activities1 .
known genetic causes in... |
ocular burns constitute true ocular emergencies , and both thermal and chemical burns represent potentially blinding ocular injuries . recovery of ocular surface burns depends upon the causative agent and the extent of damage to corneal , limbal , and conjunctival tissues at the time of injury.1 developments in the man... | purposewe describe a case of full - thickness corneal restoration after an acute corneal burn with an acid agent.methodsa 32-year - old male reported painful discomfort , redness , photophobia , and a decrease in visual acuity in the left eye after a unilateral burn with an acid agent .
slit - lamp examination reveal... |
resistance exercise using weight machines or body weight builds muscle strength , helps
rehabilitate athletes , prevents injuries , and improves health in typical adults1 .
resistance exercises can be categorized
biomechanically into open kinetic chain ( okc ) and closed kinetic chain ( ckc ) exercises .
okc
... | [ purpose ] this study investigated the effects of combined open kinetic chain and closed
kinetic chain training using pulley exercise machines on muscle strength , anaerobic power ,
and blood levels of angiogenesis factors .
[ subjects and methods ] twenty male university
students were equally divided between ... |
rotator cuff tears are very common injuries ; ruptures generally occur within the tendon or as an avulsion from the greater tuberosity [ 1 , 2 ] .
musculotendinous ruptures are common both in the upper and in the lower extremities ; ruptures of the rotator cuff through the musculotendinous junction are exceptional . ... | the vast majority of rotator cuff tears occur within the tendon or as an avulsion from the greater tuberosity .
supraspinatus injury at the musculotendinous junction is a very uncommon event .
we describe a case of supraspinatus rupture at the musculotendinous junction , with successful conservative treatment .
i... |
the american heart association s ( aha s ) strategic planning task force and statistical committee recently implemented 2020 impact goals for cardiovascular health promotion called life s simple 7 ( 1 ) . these goals are based on the current understanding of modifiable risk factors for cardiovascular disease ( cvd ) an... | objectivethe american heart association s recommendations for optimal health , summarized in life s simple 7 , have been associated with reduced risk of cardiovascular disease ( cvd)-related end points , but no studies have examined the association of these goals with incident type 2 diabetes , which is associated with... |
it is the definitive management option for thyroid malignancies and also for benign diseases such as multinodular goiter symptomatic of compression . in the hands of an experienced surgeon , it is a safe procedure .
main postoperative complications include bleeding , recurrent laryngeal nerve injury , and hypocalcemi... | background : total thyroidectomy ( tt ) is a commonly performed surgery and postoperative hypocalcemia is a major detriment to early discharge .
the aim of this randomized controlled trial was to ascertain the usefulness of routine pre- and post - operative calcium and vitamin d supplementation in prevention of hypoc... |
non - accidental ingestion of foreign bodies rarely occurs in adults but should be recognized as a risk factor in those with psychiatric illnesses or learning difficulties .
we report a case of multiple magnet ingestion in an adult with learning difficulties , to highlight the associated abdominal complications .
a... | non - accidental ingestion of foreign bodies rarely occurs in adults .
we report a case of multiple magnet ingestion in an adult with learning difficulties to highlight the associated abdominal complications .
multiple magnets may not pass through the gastrointestinal tract spontaneously and approach considerations... |
esophageal intramural pseudodiverticulosis ( eipd ) is a rare disease of unknown origin which was first described by mendl in 1960 . in the majority of cases dysphagia , which sometimes slowly progresses ,
eipd is often associated with gastroesophageal reflux , chronic alcohol abuse , diabetes and candida infection ,... | esophageal intramural pseudodiverticulosis ( eipd ) is a rare disease of unknown etiology that displays multiple pseudodiverticula radiologically , leading to benign esophageal stricture .
dysphagia , which sometimes slowly progresses , is the main symptom in the majority of cases .
we here report a 59-year - old m... |
severe sepsis , septic shock , and the resulting multiple organ failure / dysfunction syndrome represent an ongoing challenge in intensive care units [ 15 ] . with mortality ranging from 40% to 70% ,
septic shock is the most common cause of death in intensive care medicine [ 2 , 6 ] . despite intensive basic ... | background .
redox active substances ( e.g. , thioredoxin-1 , macrophage migration inhibitory factor ) seem to be central hubs in the septic inflammatory process .
materials and methods .
blood samples from patients with severe sepsis or septic shock ( n = 15 ) were collected at the time of sepsis diagnosis ( t0 ... |
one of the goals of occupational therapy is to help improve the performance of functional
tasks in daily life1 . in particular , hand
and upper extremity activities play an important role in tasks of daily living such as
dressing , using a keyboard , eating and so forth2 .
one of the important systems involved ... | [ purpose ] this study measured % isolation and investigated whether it shows a difference
between the presence and absence of wrist joint restriction , as well as changes in muscle
activity patterns .
[ methods ] twenty subjects performed upper extremity functional movement
in the manual function test ( mft ) ... |
as in most other developing nations , critical care medicine as a specialty has developed very slowly and only recently in india . the coronary care units were developed in the early to mid-1970s .
perhaps the main pioneer of the field of critical care in india was farokh e udwadia , a brilliant physician with intern... | critical care practices in india have evolved significantly over the past decade .
critical care initially began as a service in major hospitals , but with the formation of the indian society of critical care medicine the development of this speciality has been very rapid .
regular conferences , updates , continuin... |
secondary surgery of the neck for persistent or recurrent thyroid cancer ( tc ) is still the subject of debate .
the advocated extent of the salvage neck dissection ( nd ) has not been established yet .
subsequent procedure for the central compartment ( cc ) carries the risk related directly to the anatomy of this ... | the purpose of the study was to assess the feasibility of secondary neck dissections ( nd ) in different types of thyroid cancer ( tc ) , to evaluate the influence of nd extent on morbidity and to describe biochemical and clinical outcomes .
51 patients previously operated for tc ( 33-well differentiated tc - wdtc , ... |
the spondyloarthritides ( spa ) are a group of inflammatory rheumatic disorders related by clinical symptoms and genetic predisposition .
they include ankylosing spondylitis ( as ) , psoriatic arthritis ( psa ) , reactive arthritis , inflammatory bowel disease- ( ibd- ) related spa , and undifferentiated spa .
they... | data on spondyloarthritis ( spa ) from the middle east are sparse and the management of these diseases in this area of the world faces a number of challenges , including the relevant resources to enable early diagnosis and referral and sufficient funds to aid the most appropriate treatment strategy . the objective was ... |
population aging has increased public interest in maintaining a healthy and high - quality
life1 .
methods to prevent the functional
disorders of the elderly , lengthen the span of their healthy lives , and reduce their social
and economic burdens are needed2 , 3 . in recent years
, customized exercise
meth... | [ purpose ] the purpose of this study was to examine the effects of a muscle strengthening
exercise program using an elastic band on changes in the physical abilities and quality of
life of the rural elderly .
[ subjects ] the subjects of this study were 46 elderly people ( 8
males , 38 females ) aged 65 or old... |
sebaceous carcinoma , first described by allaire in 1891 accounts for less than 1% of all cutaneous malignancies .
it is a rare but aggressive malignant neoplasm that arises from sebaceous glands with a tendency for both local recurrence and distant metastases .
we report a case of an extraocular type of sebaceous ... | extra ocular sebaceous carcinoma is a rare malignancy when compared to peri ocular variant and these are derived from sebaceous gland epithelium .
the aggressive types of extra ocular sebaceous neoplasm are reported with lymph node and visceral metastasis associated with poor prognosis . here
we report a case of ex... |
parkinson s disease ( pd ) is the second most frequent age - associated brain degeneration disorder , affecting about 1 % of the population over 65 years of age .
the pd - specific progressive movement deficit is mostly due to the severe affliction and cell death of midbrain nigrostriatal dopaminergic neurons .
s... | as the second most frequent neurodegenerative disorder of the aging population , parkinson s disease ( pd ) is characterized by progressive deficits in spontaneous movement , atrophy of dopaminergic midbrain neurons and aggregation of the protein alpha - synuclein ( snca ) . to elucidate molecular events before irrever... |
holoprosencephaly ( hpe ) is a type of central nervous system malformation resulting from hypoplasia or aplasia of the most rostral end of the neural tube and premaxillary segment of the face .
it is characterized by varying degrees of incomplete separation of the cerebral hemispheres and deep brain structures such a... | middle interhemispheric variant ( mih ) of holoprosencephaly ( hpe ) or syntelencephaly is a rare variant of hpe characterized by abnormal midline union of the posterior frontal and parietal lobes with variable fusion of thalami .
it varies from classic hpe in embryopathogenesis , severity of fusion of brain structur... |
dry eye disease ( des ) is a major tear deficiency disorder which causes discomfort , visual disturbances , and tear film instability with potential damage to the ocular surface .
the tear film and ocular surface form a complex and stable system that can lose its equilibrium through multiple disturbing factors . desp... | purpose . to evaluate the pooled prevalence rate and risk factors of dry eye symptoms ( des ) in mainland china
. methods . all the published population - based studies investigating the prevalence of des in china were searched and evaluated against inclusion criteria . a systematic
review and meta - analysis were ... |
on ageing , a nonmodifiable cardiovascular risk factor , hypertension becomes the most important modifiable risk factor for developing cerebrovascular disease , including stroke , cerebral small vessel disease ( lacunar infarcts , white matter lesions , microbleeds ) , and cognitive impairment or vascular dementia .
... | silent cerebral white matter lesions ( wmls ) are a common finding on magnetic resonance imaging of the brain in the elderly . however , in patients with hypertension , wmls tend to occur earlier in life and appear to be more severe .
there is a body of evidence that supports the idea that wmls in asymptomatic hypert... |
across a very broad taxonomic range animals frequently respond differentially to close kin , even if those kin were previously unfamiliar . logically , this differentiation between individuals according to kinship requires well - defined mechanisms to allow recognition . and whereas animals may learn the cues of famili... | a recent study in bmc evolutionary biology has shown that genetically similar individual ring - tailed lemurs are also more similar in their scent composition , suggesting a possible mechanism of kin recognition .
theoretical and experimental studies reveal challenges ahead in achieving a true systems - level underst... |
alopecia can be a manifestation of mycosis fungoides ( mf ) ; however , the prevalence is unknown .
alopecia is a typical consequence of folliculotropic variant of mf ( f - mf ) , although due to the paucity of f - mf , data regarding detailed findings in these patients are limited .
primary cutaneous t - cell lymp... | background : alopecia can be a manifestation of mycosis fungoides ( mf ) ; however , the prevalence is unknown.aims:we sought to describe the clinicopathologic presentation of alopecia in patients with diagnosis of mf.methods:a retrospective analysis of patients with biopsy - proven mf , who were evaluated at our cance... |
however , it has a higher frequency among patients younger than 40 years , patients with thrombophilia and patients that have foreign body such as catheter in their veins or arterial system .
in this case report , we described the clinical and radiological findings of a patient who developed cerebral vein thrombosis ... | backgroundcerebral venous thrombosis is an uncommon disorder in the general population .
however , it has a higher frequency among patients younger than 40 years , patients with thrombophilia and patients that have foreign body such as catheter in their veins or arterial system.case detailsin this case report , we de... |
for those patients presenting with symptoms of small - bowel obstruction , the list of differential diagnoses is vast , with numerous extramural , mural and luminal causes . in this report
, we describe two cases that presented with a history and imaging suggestive of small - bowel obstruction . both had deranged clo... | spontaneous intramural haemorrhage is a rare cause of small - bowel obstruction , occurring most commonly in those who are anticoagulated .
we describe two cases that presented with a history and imaging suggestive of small - bowel obstruction ; both had international normalized ratios of above 10 on admission .
th... |
in accordance with the goals of this special issue of metal - based drugs , this article deems to
fulfil a teaching and guiding role in new anticancer drug research .
we hope it will spawn new ideas and new
research in the field of anticancer therapy . in what follows ,
we first create an understanding of why n... | the general synthetic strategy towards water - soluble biodegradable drug carriers and the properties that they must have are discussed .
the syntheses of water - soluble biodegradable copolymers of lysine and aspartic acid as potential drug - delivering devices , having amine - functionalised side chains are then de... |
regeneration of dentin - pulp complex is the long - term goal of endodontics and restorative dentistry .
recently , there has been an increasing interest in applying the concept of tissue engineering to endodontics . the creation and delivery of new tissues to replace diseased , missing , or traumatized pulp
potent... | aim : the objective of this survey was to study the level of awareness , current state of knowledge and opinions towards regenerative endodontic treatments amongst the endodontic residents of india.settings and design : questionnaire based survey was designed.materials and methods : after approval from the organizing c... |
radiology plays an important role in the diagnostic assessment of dental patients . for this reason ,
several imaging methods have been introduced and employed to improve the accuracy of diagnosis and treatment plans .
cone - beam computed tomography ( cbct ) is a novel imaging technology that has been used in the ... | background : cone - beam computed tomography ( cbct ) is a new imaging technology that has been widely used in implantology , oral and maxillofacial surgery and orthodontics .
this method provides 3-d images that are composed of voxel , which is the smallest image unit , and determines image resolution .
smaller vo... |
home
testing for chlamydia and gonorrhea has high sensitivity ( about 90% ) and
specificity ( > 99% ) , and is well accepted in adolescent and young adult
populations [ 13 ] .
studies in the us and in denmark demonstrate that
home testing significantly increases the likelihood that tests will occur [ 1 , 2 ] ... | home testing for chlamydia and gonorrhea increases
screening rates , but the cost consequences of this intervention
are unclear .
we examined the cost differences between home - based
and clinic - based testing and the cost - effectiveness of home
testing based on the daisy study , a randomized controlled tri... |
replication stress is a well - characterized tumor characteristic and has recently been considered as a potential new hallmark of cancer ( macheret and halazonetis , 2015 ) .
replication stress leads to the activation of the dna damage response ( ddr ) , which is associated with the early stages of cancer development... | summarycells exposed to hypoxia experience replication stress but do not accumulate dna damage , suggesting sustained dna replication .
ribonucleotide reductase ( rnr ) is the only enzyme capable of de novo synthesis of deoxyribonucleotide triphosphates ( dntps ) .
however , oxygen is an essential cofactor for mam... |
a liberian man 47 years of age living in the united states traveled to liberia in january 2010 .
he arrived in monrovia , then spent 5 days traveling throughout nimba county in north - central liberia , bordering guinea and cte divoire .
he reported sleeping nightly in his rural native village in a dwelling infeste... | we report a case of lassa fever in a us traveler who visited rural liberia , became ill while in country , sought medical care upon return to the united states , and subsequently had his illness laboratory confirmed .
the patient recovered with supportive therapy .
no secondary cases occurred . |
some penicillins have been reported to cause occupational diseases , including bronchial asthma ( 1 , 2 ) , anaphylaxis ( 3 ) , contact urticaria ( 4 ) , contact dermatitis ( 5 ) , and hypersensitivity pneumonitis ( 6 ) , in pharmaceutical workers and health care professionals .
occupational contact urticaria and ana... | this is the first reported detection of serum ige antibody to piperacillin - human serum albumin ( hsa ) conjugate in a patient presenting with anaphylaxis that developed after occupational exposure . a 24-yr - old nurse , who had worked at a university hospital for 2 yr , experienced chest tightness , dizziness , gene... |
an electrical storm ( es ) in ischaemic heart disease usually manifest as recurrent ventricular arrhythmias that are resistant to the antiarrhythmic drugs .
we report an incident of es in a patient , which was treated with left stellate ganglion block ( lsgb ) under ultrasound guidance followed by left cardiac sympat... | an electrical storm is usually associated with catecholaminergic surge following myocardial ischaemia and manifest as recurrent ventricular arrhythmias , requiring frequent dc shocks . delivering repeated dc shocks
induces myocardial damage and further worsens the arrhythmias , which are resistant to the antiarrhythm... |
there is currently no vaccine available for any form of leishmanias , including visceral leishmaniasis ( vl ) , which if left untreated is almost always fatal .
vl results from systemic infection with l. infantum ( also known as l. chagasi ) which occurs in europe , north africa , south and central america , and l.... | leishmaniasis is a neglected disease resulting in a global morbidity of 2,090 thousand disability - adjusted life years and a mortality rate of approximately 60,000 per year . among the three clinical forms of leishmaniasis ( cutaneous , mucosal , and visceral ) ,
visceral leishmaniasis ( vl ) accounts for the majori... |
dynamic
rna nanotechnology based on programmable hybridization
cascades with small conditional rnas ( scrnas ) offers a promising conceptual
framework for engineering programmable conditional regulation in vivo .
while single - base substitution ( sbs ) somatic mutations and single - nucleotide
polymorphisms ... | |
the formation of cysts in the jaws possesses
unique features regarding their pathology and implicates the odontogenic
tooth - forming apparatus . in most classification schemes odontogenic
cysts are divided in two major categories , namely the developmental
cysts and the cysts that are initiated in areas of acu... | abstractobjectives odontogenic keratocysts ( okcs ) are developmental
cysts that have been reclassified according world health organization
( who ) , to keratocystic odontogenic tumours ( kcots ) , a term that better
reflects their neoplastic nature . the aim of present study is to
evaluate the induction of str... |
predominantly found in the tendon sheaths or joints of the fingers and toes , and rarely in larger joints such as the knee or ankle.12 although localized nodular synovitis involving the infrapatellar fat pad has been occasionally reported,34 mechanical symptoms such as locking or restricted knee motion are rare , with ... | we report a case of localized nodular synovitis of the infrapatellar fat pad impinging on the patellofemoral joint causing limitation of extension .
arthroscopy involved use of a superolateral portal because location of lesion hindered access via a conventional anterior portal .
the infrapatellar mass impinged in t... |
malignant tumors of the exocrine pancreas occur mainly in adults in their sixth or seventh decade of life .
they commonly present with late - stage disease , and have poor prognosis , even in cases with primary resectable disease .
less frequent histologies include intraductal papillary mucinous neoplasms with tran... | pancreatic tumors are rare in children and adolescents . here , we report the case of a 15-year - old boy who presented with a mixed acinar cell carcinoma / ductal adenocarcinoma with blastomatous components .
he received multimodal treatment including various chemotherapy regimens and multistep surgery including liv... |
over the last 15 years , laparoscopy has been inexorably integrated into urologic practice .
however , during this transition period , urologic training programs are only now beginning to provide systematic and fundamental minimally invasive surgery ( mis ) training to residents .
additionally , there remains a si... | laparoscopy has found a role in standard urologic practice , and with training programs continuing to increase emphasis on its use , the division between skill sets of established non - laparoscopic urologic practitioners and urology trainees continues to widen . at the other end of the spectrum , as technology progres... |
testicular microlithiasis ( tm ) is an uncommon pathologic condition that is commonly diagnosed by scrotal ultrasonography .
the characteristic ultrasound ( us ) appearance of tm involves multiple bright foci , 1 to 2 mm in diameter , that are limited to the testicles .
there is little or no acoustic shadowing , an... | purposetesticular microlithiasis ( tm ) is an uncommon pathologic condition that is commonly diagnosed by scrotal ultrasonography .
indirect evidence suggests that this syndrome may be associated with an increased risk of testicular malignancy and infertility.materials and methodsa total of 1,439 patients undergoing ... |
17-estradiol ( e2 ) is a member of the family of steroid hormones which controls many aspects of mammalian physiology .
although its ability to stimulate breast cell proliferation is one of e2 normal roles , it increases the risk of breast cancer [ 1 , 2 ] .
classically , e2 actions are mediated upon binding on two... | goiter is more common in women , suggesting that estrogen could be involved in its physiopathology .
the presence of classical estrogen receptors ( er and er ) has been described in thyroid tissue , suggesting a direct effect of estrogen on the gland .
a nonclassic estrogen receptor , the g - protein - coupled estr... |
transfusion - dependent -thalassemia major ( -tm ) is a type of inherited blood disorder resulting in severe and chronic anemia .
multi blood transfusion regimen is the first effective measure in prolonging life among these patients ; however , excessive iron overload caused by repeated blood transfusions can resu... | there are few papers on the combination therapy of deferiprone ( dfp ) and deferasirox ( dfx ) in iron - overloaded patients with transfusion - dependent -thalassemia major ( -tm ) .
a total of 6 patients with -tm ( 5 males and 1 female ) with a mean age of 23.85.8 years ( ranging from 17 to 31 ) used this treatment ... |
bifid mandibular condyle is an uncommon anomaly with an unclear origin , which was first described in 1941 by hardlicka .
the condylar head is divided into two partially or completely separated lobes by a rift or a deep groove .
the separating groove can be oriented anteroposteriorly or mediolaterally to determine ... | objectives : differential diagnosis of bifid mandibular condyle ( bmc ) is important , since it may play a role in temporomandibular joint ( tmj ) dysfunctions and joint symptoms .
in addition , radiographic appearance of bmc may mimic tumors and/or fractures .
the aim of this study was to evaluate the prevalence a... |
twelve partial hydatidiform moles , 12 complete hydatidiform moles , 12 choriocarcinomas , and 14 first - trimester nonhydropic spontaneous abortions ( control group ) diagnosed previously in the qhaem and imam reza department of pathology , mashhad university of medical sciences were included in the study after reeval... | background : despite well - described histopathologic criteria , the distinction of spontaneous abortion from hydatidiform mole and complete hydatidiform mole from partial hydatidiform mole remains a problem because of interobserver and intraobserver variability .
the aim of this study was to evaluate the value of tw... |
monocytes / macrophages play a critical role in managing innate and adaptive immunity - including inflammatory processes by secreting proinflammatory molecules ( eg . tumor necrosis factor ( tnf)- , and nitric oxide ( no ) ) .
the activation of macrophages and monocytes is mediated by activation of various receptors ... | cinnamaldehyde ( ca ) has been known to exhibit anti - inflammatory and anticancer effects .
although numerous pharmacological effects have been demonstrated , regulatory effect of ca on the functional activation of monocytes and macrophages has not been fully elucidated yet . to evaluate its monocyte
/ macrophag... |
progressive systemic sclerosis ( pss ) is an inflammatory disease of connective tissue , with onset as edema that continues with fibrosis , induration , and skin atrophy , followed by attacks on the joints , internal organs , and secondary proliferation of connective tissue ( 1 ) .
other attacked organs besides the s... | introduction : progressive systemic sclerosis ( pss ) is an inflammatory disease of connective tissue , with onset as edema that continues with fibrosis , induration , and skin atrophy , followed by attacks on the joints , internal organs , and secondary proliferation of connective tissue.purpose:to research in which r... |
isotretinoin ( 13-cis - retinoic acid ) , a synthetic analog of vitamin a , is used primarily for severe cystic acne and acne that has not responded to conventional treatments .
they include abnormal meibomian gland secretion , blepharoconjunctivitis , corneal opacities , decreased dark adaptation , decreased toleran... | isotretinoin a synthetic analogue of vitamin a is primarily used for cystic acne not responding to conventional treatment .
several ocular side effects including blurring of vision , decreased dark adaptation , corneal opacities and meibomian gland atrophy have been reported with prolonged use of isotretinoin .
the... |
although spontaneous spinal epidural haematoma ( sseh ) is a low incidence condition , it is widely recognised throughout the literature as a cause of myelopathy [ 5 , 15 ] .
the relationship between sseh and anticoagulant therapy is well known and the probable cause of bleeding is thought to be the rupture of the ve... | introduction : spontaneous spinal epidural haematoma ( sseh ) is widely recognised throughout the literature as a cause of myelopathy , radicular compression being very rarely reported . surgical management is almost always recommended , especially in the cases of spinal cord compression .
conservative treatment is r... |
to provide maximal efficacy in preventing cardiovascular events , -blockers should be present at sufficient strength over the entire 24-h day.this modeling study showed that bisoprolol and metoprolol succinate provide comparable overall blood pressure - lowering activity.however , there are differences between the two... | objectiveto compare the effects of bisoprolol and metoprolol cr / zok ( metoprolol succinate controlled release ) on systolic blood pressure ( bpsys ) over a 24-h period in an in silico model.methodson the basis of the observed data from ambulatory blood pressure measurements ( abpm ) , a model with an appropriate dis... |
recent advances in high - throughput sequencing technologies have enabled us to determine many genomic sequences quickly and cheaply .
the use of biological sequence information has greatly facilitated the r&d process in the pharmaceutical , agricultural , medical and chemical industries ( 1 ) .
sequences patent ow... | with the advent of automated and high - throughput techniques , the number of patent applications containing biological sequences has been increasing rapidly .
however , they have attracted relatively little attention compared to other sequence resources .
we have built a database server called patome , which conta... |
since the special quartz fiberoptic transmission system was developed , it is possible to apply laser energy through a flexible fiber endoscope .
after the first use of the endoscopic laser for the treatment of active gastrointestinal bleeding in 1975 , by fruhmorgen , endoscopic laser therapy has been widely used , ... | with the development of a special quartz fiberoptic transmission system , the application of laser energy through an endoscope became possible .
now , endoscopic laser therapy is widely used for gastrointestinal bleeding , and gastrointestinal neoplasm , and we have removed broad - based gastric polyps using an endos... |
metabolic pathway models consist of enzymatic reactions described by their stoichiometry , the enzymatic rate laws , and their kinetic constants ( such as , for instance , equilibrium constants or catalytic constants ) .
the more we know about these quantities , the more reliably we can simulate the metabolic dynamic... | kinetic modeling of metabolic pathways has become a major field of systems biology .
it combines structural information about metabolic pathways with quantitative enzymatic rate laws .
some of the kinetic constants needed for a model could be collected from ever - growing literature and public web resources , but t... |
flaccidity appears during the early stage after stroke ; however , as time passes , it is
accompanied by spasticity , which occurs in 90% of stroke patients .
in particular , spasticity of the ankle plantar flexor
disrupts static and dynamic balance , as well as the normal gait pattern1 , 2 . shortened calf
mus... | [ purpose ] we examined the effectiveness of mulligan s mobilization with movement ( mwm )
technique on spatiotemporal variables of gait in individuals who had a stroke . [ subjects
and methods ] twenty - four subjects were randomly divided into 2 groups : mulligan s
mobilization with movement group ( n=12 ) and ... |
we report a case of a 63-year - old male who presented to the outpatient department with complaints of hoarseness of voice and throat pain of three months duration .
clinical , otorhinolaryngological and cytological examination revealed squamous cell carcinoma of supraglotic larynx ( stage t2 n1 m0 , t = tumor , n = ... | head and neck cancers are common among men in developing countries . among head and neck cancers in the united states ,
supraglottic laryngeal cancer accounts for 12,500 new cases per year .
it responds favorably to radiotherapy with or without chemotherapy depending on the stage of disease .
recurrence is local ... |
severe epstein - barr virus ( ebv ) disease has been observed increasingly in immune deficient hosts having congenital immunodeficiency syndrome or acquired immune suppression . in an immune competent host
, ebv may be eliminated by cytotoxic t cells evoked by the ebv antigen , or the virus can survive in the human b... | severe chronic active epstein - barr virus ( ebv ) infection is a rare and life - threatening illness .
although the criteria for diagnosis include chronic or recurrent infectious mononucleosis - like symptoms lasting more than 6 months and high titers of anti - ebv antibodies , clinical and laboratory findings may b... |
phytate - degrading enzyme ( phytase , ec 3.1.3.8 ) preparations have a wide range of applications in animal and human nutrition . besides that
, these enzymes have also attracted considerable attention from both scientists and entrepreneurs in the areas of environmental protection and biotechnology .
phytases are ... | a bacterial isolate , alcaligenes sp .
secreting phytase ( ec 3.1.3.8 ) , was isolated and characterized .
the optimum conditions for the production of phytase included a fermentation period of 96 h , ph 8.0 , and the addition of 1% ( w / v ) maltose and 1% ( w / v ) beef extract to the culture medium .
this enzy... |
globally , an anticipated difficult airway is managed most often with flexible fiberoptic bronchoscope ( ffb)-guided tracheal intubation . in patients with restricted mouth opening , intubation is done through the nasal route , which is unpredictable in terms of the maximum tube size allowable . during ffb - guided int... | flexible fiberoptic bronchoscope - guided awake intubation is the most trusted technique for managing an anticipated difficult airway . even after successfully negotiating the bronchoscope into the trachea
, the possibility remains that the preloaded tracheal tube might prove to be inappropriately large , and may not... |
synovial sarcoma ( ss ) , though very rarely encountered , could also arise in this location [ 18 ] . around 80% of synovial sarcomas
tumor size of 5 cm [ 1117 ] and completeness of resection [ 16 , 18 , 19 ] are the most consistent prognostic factors among previous reports . other factors , though less consistently... | background .
the aim of this systematic review is to attempt to provide a descriptive analysis for cases of synovial sarcoma ( ss ) arising in the mediastinum and to analyze prognostic factors . methods .
we performed pubmed database search in july 2013 .
twenty - two studies , which included 40 patients , form t... |
the advent of laparoscopic surgery has led to great advances in the field of general surgery , including shorter hospitalizations , reduced postoperative pain , fewer wound infections , and improved cosmesis .
however , laparoscopic techniques also have limitations , including an unstable camera platform , the limite... | background : different skills are required for robotic surgery and laparoscopic surgery . we hypothesized that the laparoscopic experience would not affect the performance with the da vinci system . a virtual robotic simulator was used to estimate the operator 's robotic dexterity.materials and methods : the performanc... |
blood glucose homeostasis can be disturbed by many clinical conditions such as pregnancy and obesity and cause -cell mass expansion to meet the increased demand of insulin [ 1 , 2 ] . however , the mechanism of action underlying the expansion of -cells is currently unclear [ 36 ] .
although glucose has been postulate... | the complementary role of hyperglycemia and p27kip1 suppression on islet beta cell regeneration was investigated in a syngeneic mouse model .
p27kip1 gene silencing was performed by infecting islets of c57bl/6 with shrna lentiviral particles . at 54 hours after viral infection , p27kip1 protein content in cultured ta... |
glucagon - like peptide-1 ( glp-1 ) is produced by posttranslational proteolytic cleavage of the proglucagon gene product and mainly secreted from the enteroendocrine l cells in the distal intestine in response to nutrient ingestion .
glp-1 is an incretin hormone , which increases glucose - stimulated insulin secreti... | glucagon - like peptide-1 ( glp-1 ) is an incretin hormone mainly secreted from intestinal l cells in response to nutrient ingestion .
glp-1 has beneficial effects for glucose homeostasis by stimulating insulin secretion from pancreatic beta - cells , delaying gastric emptying , decreasing plasma glucagon , reducing ... |
a widely accepted definition of diabetic peripheral neuropathy is the presence of symptoms and signs of peripheral nerve dysfunction in people with diabetes after exclusion of other causes ( boulton 1998 )
. it can be classified into several syndromes each with a distinct pattern of involvement of peripheral nerves... | diabetic neuropathy has varied clinical presentations . as clinicians
we should be aware of the common as well as rare manifestations of this syndrome .
diabetic truncal neuropathy presenting as a painful pseudoabdominal mass can easily mislead clinicians who are unaware of this problem .
subsequently , this can ... |
nickel ( ni)-containing alloys has become an integral part of almost every routine orthodontic intervention . as contemporary orthodontics relies on various bonded attachments , arch wires , and other devices to achieve tooth movement .
the demands made on them are complex because they are placed under many stresses ... | aim : the high incidence of nickel ( ni ) allergy and the increasing use of ni - containing dental biomaterials have been of growing concern . the purpose of this investigation was to analyze and evaluate the rate of ni ion release from different types arch wires used in orthodontics.materials and methods : four groups... |
glucocorticoids were among the first drug classes used in the treatment of patients with all and are still essential components of treatment .
the glucocorticoid receptors ( gr ) can form dimers , translocate to the nucleus , and interact with glucocorticoid - response elements to transactivate gene expression , or t... | interleukin 10 ( il10 ) is a pleiotropic cytokine that stimulates various hematopoietic cells .
the tumor necrosis factor alpha ( tnf ) is a cytokine that may influence the transcriptional activity induced by glucocorticoids .
this study examined the impact of tnf ( g308a ) and il10 ( g1082a ) polymorphisms at prom... |
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