Subset (2)

section · 133k rows

Split (3)

train · 120k rows

article stringlengths 0 826k	abstract stringlengths 174 4.34k
	polymorphism of cyp2d6 gene encoding for debrisoquine hydroxylase was determined genotypically for 94 controls and 77 lung cancer patients using a polymerase chain reaction - based application . both of the point mutations that give rise to deficient alleles of the cyp2d6 gene are detectable by this method . out of...
pathogenic bacterial infections afflict countless numbers of individuals annually , with outcomes ranging from minor and treatable complications to death . food and waterassociated bacterial illnesses , estimated at 76 million illnesses per year , cost the us economy well in excess of $ 10 billion annually ( buzby and ...	summarycellbased biosensors have been proposed for use as functionbased detectors of toxic agents . we report the use of betta splendens chromatophore cells , specifically erythrophore cells , for detection of foodassociated pathogenic bacteria . evaluation of erythrophore cell response , using bacillus spp . , h...
it is the main independent risk factor for developing type 2 diabetes mellitus ( t2dm),1,2 leading to a condition known as diabesity.2,3 in patients with morbid obesity , the likelihood of developing t2 dm and glucose intolerance ( gi ) is further increased.1,4 bariatric surgery provides sustained weight loss and leads...	objectiveto assess glucose homeostasis and weight loss in morbidly obese patients undergoing silastic ring sleeve gas-trectomy.methodsthis was a prospective clinical study . thirty - three female patients with a mean body mass index ( bmi ) of 42.33 1.50 kg / m2 ( range : 4045 kg / m2 ) , a mean age of 36.7 9.4 years...
obesity rapidly becomes a worldwide epidemic disease with increased risk of cardiovascular diseases , type 2 diabetes mellitus , and metabolic syndrome . metabolic syndrome is characterized by increased visceral adiposity , hyperlipidemia , insulin resistance , and hypertension . the liver is the largest visceral o...	the liver is one of the most essential organs involved in the regulation of energy homeostasis . hepatic steatosis , a major manifestation of metabolic syndrome , is associated with imbalance between lipid formation and breakdown , glucose production and catabolism , and cholesterol synthesis and secretion . epidem...
neurofibrillary tangles ( nft ) are the cardinal intracellular lesion of alzheimer disease ( ad ) , and are also found in normal aging , albeit to a lesser extent . highly phosphorylated tau protein is considered the predominant proteinaceous component of nft 1 , however , numerous other proteins have also been local...	in alzheimer disease , neuronal degeneration and the presence of neurofibrillary tangles correlate with the severity of cognitive decline . neurofibrillary tangles contain the antigenic profile of many cell cycle markers , reflecting a re - entry into the cell cycle by affected neurons . however , while such a cell...
breast cancer is the most common form of cancer among women in developed countries ; and 12% of all breast cancers are diagnosed among women aged 20 - 34 . breast cancer has the second place after skin cancer in iran in both sexes in terms of prevalence . it is the most common malignancy in iranian women and is the...	backgroundclinical experiences have revealed that patients with breast cancer experience various sexual problems following their treatment . breast cancer negatively impacts the sexual life of the afflicted couples , and as a traumatic event can influence women s psychosexual functioning and intimate relationship . ...
hair loss is a common problem encountered either due to pathological causes or nutritional deficiencies . there are various tests available to investigate hair loss such as hair pull test , hair pluck test ( trichogram ) , phototrichogram , digital phototrichogram , unit area trichogram , hair diameter assessment , a...	aim : to assemble a simple , inexpensive hand - held trichotillometer and to determine the epilation force ( ef ) required to pluck the anagen hair and telogen hair from four regions of the scalp in healthy volunteers.materials and methods : a simple hand - held trichotillometer was assembled by modifying a laboratory ...
nutrition ( that is , eating food ) is not only a prerequisite for survival ; it is also a frequently enjoyable and social function . as a consequence , when the ability to swallow is impaired ( dysphagia ) people with neuromuscular disease may develop acute respiratory failure and be admitted to critical care for me...	post - extubation dysphagia is a common and serious problem . the presence of neuromuscular disease at the time of intubation is likely to increase this . until recently , the prevalence and the association with length of intubation had not been clarified . results published in this journal suggest that 93% of ex...
musculoskeletal disorders ( msds ) are a major problem for patients as well as for society and can lead to functional limitation and absence from work [ 1 , 2 ] . health care workers have physically and psychologically demanding work and are at high risk of developing long term msds and sickness absence [ 35 ] . re...	purpose the aim of this study was to describe self - reported and physically tested function in health care workers with musculoskeletal disorders ( msds ) and to examine how function was associated with work participation.methodsa cross - sectional study was conducted . 250 health care workers attended an evaluati...
breast cancer remains the leading cause of cancer related morbidity and mortality in women , worldwide . every tenth new cancer diagnosed is that of breast , and nearly a quarter of cancers in the women are breast cancer . about 1.4 million new breast cancer cases are diagnosed every year , and the burden is going ...	the choice of adjuvant hormonal therapy in postmenopausal women with hormone receptor positive breast cancer has remained a matter of controversy and debate . the variety of agents is available , with each claiming to be superior . this clinical survey was undertaken to get an impression of the physician 's first c...
acetyl - coa carboxylase ( ec6.4.1.2 ) ( acc ) is a biotin carboxylase that catalyzes the atp - dependent condensation of acetyl - coa and carbonate to form malonyl - coa . it is an essential and rate - limiting substrate for de novo lipogenesis ( dnl ) , and it acts as an allosteric inhibitor of the enzyme...	acetyl - coa carboxylase ( acc ) inhibitors offer significant potential for the treatment of type 2 diabetes mellitus ( t2 dm ) , hepatic steatosis , and cancer . however , the identification of tool compounds suitable to test the hypothesis in human trials has been challenging . an advanced series of spiro...
hypnic headache ( hh ) is a primary headache disorder characterized by attacks that occur only during sleep . it was first described by raskin in 1988 . since then , about 100 similar cases have been reported in the literature . however , recently two cases of probable hh are reported in the children less than 10 ...	hypnic headache ( hh ) is a rare sleep - associated primary headache disorder that usually begins after the age of 60 years . here we report a 19-year - old male with 4-year history of predominantly left sided hh . he is the youngest person reported who fulfills the ihs diagnostic criteria for hh . the patient h...
social media , web - based applications , and internet has revolutionized communication process over the last 2 decades . similarly , learning and teaching process in the field of medicine had transformed slowly and progressively to suit the changes according to the geographical and economic constraints . we in thi...	background / aim : significant change has been happening in the introduction of technology in medical teaching all over the world . we aim to determine if the undergraduate medical students and teachers are open to incorporating changes in the current medical curriculum or if there is a need for the same in the republi...
control of the trunk of the body is a necessary condition for humans to maintain their balance against gravity1 . however , patients with stroke caused by brain damage experience a diminished ability to balance because of the weakened muscle strength of the trunk2 . training to control the trunk and maintain ...	[ purpose ] the aim of this study was to investigate the effects of proprioceptive neuromuscular facilitation neck pattern exercise on the ability to control the trunk and balance in chronic stroke patients . [ subjects and methods ] a total of 30 study subjects were selected and randomly divided into an experime...
forty years ago , given the evidence available , it was appropriate to label ldl ( low - density lipoprotein ) , bp ( blood pressure ) and smoking as risk factors rather than causes of vascular disease . all the links in the evidentiary chain of causality temporality , strength , dose response , specificity , consi...	primary prevention of cardiovascular disease is governed at present by the risk factor model for cardiovascular events , a model which is widely accepted by physicians and professional associations , but which has important limitations : most critically , that effective treatment to reduce arterial damage is often dela...
corneal neovascularization is defined as the occurrence of neovessels developed from preexisting vascular structures in the limbus , invading areas of the cornea initially not vascularized . the avascular character results from a balance between angiogenic and antiangiogenic factors . in pathological conditions such as...	introduction . corneal neovessels are a major risk factor for corneal graft rejection , due to the loss of the immune privilege . the purpose of this study is to evaluate the effectiveness of intrastromal injection of bevacizumab in the treatment of corneal neovascularization . material and methods . this is a ...
short - term memory ( stm ) persists for several hours at most , while long - term memory ( ltm ) can last for up to a lifetime . a clear biochemical feature of memory consolidation at the cellular level , which occurs immediately after learning ( an episode ) , is the induction of gene expression . this gene expre...	camp response element - binding protein ( creb ) , a transcription factor , has been shown to play a central role in memory formation , and its involvement in this process has been investigated using a wide range of animal models , from nematodes to higher animals . various creb mutant mice have been developed and in...
although new bedford harbor ( nbh ) , ma , is one of the largest polychlorinated biphenyl ( pcb ) superfund sites in the united states , it has not been studied as an important source of airborne pcbs . in 1983 , nbh was placed on the national priorities list of superfund cleanup sites because of the extremel...	qualitatively and quantitatively , we have demonstrated that airborne polychlorinated biphenyl ( pcb ) concentrations in the air surrounding new bedford harbor ( nbh ) are caused by its water pcb emissions . we measured airborne pcbs at 18 homes and businesses near nbh in 2015 , with values ranging from 0.4...
endobronchial fibroepithelial polyps are a rare neoplasm with only a few case reports in the english literature ( 1 - 4 ) . histologically , these lesions are composed of collagen fibers in a stroma covered by normal respiratory epithelium ( 3 ) . we report a case of a fibroepithelial polyp of the bronchus , of whi...	a fibroepithelial polyp of the bronchus is a rare , benign , and endobronchial tumor , histologically consisting of fibrovascular stroma covered by normal respiratory epithelium . we report a case of a fibroepithelial polyp arising from the left main bronchus . on ct , a characteristic lobulating contour of the end...
multiple sclerosis ( ms ) is an immune - mediated disease of the central nervous system with a relapsing - remitting course in the majority of the early stages of the disease . as for other multifactorial diseases this limits the opportunities provided by the advancements in genetics , immunology , and neurobiology s...	heritable and nonheritable factors play a role in multiple sclerosis , but their effect size appears too small , explaining relatively little about disease etiology . assuming that the factors that trigger the onset of the disease are , to some extent , also those that generate its remissions and relapses , we attempte...
polycystic ovary syndrome ( pcos ) is a heterogeneous disorder characterized by chronic anovulation and the cutaneous effects of hyperandrogenism [ 13 ] . there is a high prevalence of pcos in women with type 2 diabetes mellitus , and there is evidence that insulin resistance and associated compensatory hyperinsulina...	for to determine the effect of diamel on the insulin resistance , insulin sensitivity , and sexual hormones results in women with polycystic ovary syndrome ( pcos ) . a study was carried out on 37 patients with this disorder . a triple - blind clinical trial was designed in which the diamel food supplement was comp...
sexual instinct which is the cause of numerous changes in an individual s life could be influenced by different factors such as menopause and ageing . participants were 174 menopausal women who referred to medical health centers of isfahan , iran . data were collected through self constructed sexual dysfunctions qu...	background : sexual instinct which is the cause of numerous changes in an individual s life could be influenced by different factors such as menopause and ageing . this study was designed to compare sexual dysfunction before and after menopause.materials and methods : this was a cross - sectional study . participan...
thoracic aortic aneurysms have altered cellular composition and degeneration of the extracellular matrix in the aortic wall . there are several different etiologies of thoracic aortic aneurysm such as monogenic syndromes ( marfan and loeys - dietz syndromes ) , aneurysm associated with bicuspid aortic valves , and id...	thoracic aortic aneurysm develops as a result of complex series of events that alter the cellular structure and the composition of the extracellular matrix of the aortic wall . the purpose of the present work was to study the cellular functions of endothelial and smooth muscle cells from the patients with aneurysms o...
implant restoration is a common practice and considered the first choice for replacing maxillary anterior teeth . one of the challenges in restoring anterior space with implant restoration is maintaining natural looking for the restoration . to reach patient satisfaction , optimal esthetic result has to be achieved...	one of the challenges in restoring anterior space with implant restoration is maintaining the natural looking of peri - implant area . this case report presents a clinical procedure to create the soft tissue emergence profile for anterior maxillary teeth . a 49-year - old male presented with missing right maxillary l...
it has a dual structure , with the upper part of the joint being ligamentous and the lower part of the joint being a true synovial joint . the sij moves in several planes , with the largest plane of motion being sagittal . in this plane , the sij has been reported to have 24 degrees of flexion extension ( nutation ...	backgroundsacroiliac joint ( sij ) fusion ( sijf ) , first performed 95 years ago , has become an increasingly accepted surgical option for chronic sij dysfunction . few studies have reported intermediate- or long - term outcomes after sijf.objectivethe objective of this study is to determine patient - based outcomes...
biological nitrification and denitrification are key processes to remove nitrogen from wastewater and have become more important due to stringent discharge regulations . research has shown that nitrifier 's population ( ammonia oxidizing bacteria ( aob ) + nitrite oxidizing bacteria ( nob ) ) should be more than 58% ...	this study used two laboratory - scale sequencing batch reactors ( sbrs ) to evaluate the shifts in nitrification kinetics and microbial communities of an activated sludge sewage treatment system ( main stream ) during bioaugmentation with nitrifiers cultivated on real sludge reject water ( side stream ) . although b...
because traditional methods only provide a static picture of the chromatin landscape , it is not surprising that steve henikoff ( fred hutchinson cancer research center , seattle ) , who gave the first talk , chose to summarize efforts from his lab to develop newer methodologies that allow the study of a highly dynamic...	with the goal of discussing how epigenetic control and chromatin remodeling contribute to the various processes that lead to cellular plasticity and disease , this symposium marks the collaboration between the institut national de la sant et de la recherche mdicale ( inserm ) in france and the university of california ...
millions of medical devices are used each year , and despite many advances in biomaterials , a proportion of each type of device becomes colonized by bacteria.1 implanted devices may be colonized by bacteria at the time of surgery or via a hematogenous route from a distant source . the most significant factor in the ...	backgroundthe attachment and initial growth of bacteria on an implant surface dictates the progression of infection . treatment often requires aggressive antibiotic use , which does not always work . to overcome the difficulties faced in systemic and local antibiotic delivery , scientists have forayed into using al...
dendrimer - encapsulated nanoparticles ( dens ) are well - defined nanoparticles having sizes ranging from just a few atoms to perhaps 300 atoms . this is the most scientifically interesting range of metal particle sizes because the addition of just a few atoms can drastically change their optical , electrica...	here we outline a new method for synthesizing fully reduced pt dendrimer - encapsulated nanoparticles ( dens ) . this is achieved by first synthesizing cu dens of the appropriate size through sequential dendrimer loading and reduction steps , and then galvanically exchanging the zerovalent cu dens for pt . ...
the accord trial was a double 2 2 factorial trial designed to test the effect of 1 ) intensive glucose control versus standard control , 2 ) intensive blood pressure control versus standard control , and 3 ) lipid treatment strategy that used fenofibrate plus a statin compared with statin monotherapy on the composite ...	objectiveto assess the reversibility of the elevation of serum creatinine levels in patients with diabetes after 5 years of continuous on - trial fenofibrate therapy.research design and methodsan on - drug / off - drug ancillary study to the action to control cardiovascular risk in diabetes ( accord ) lipid trial to in...
after the first characterization of thiol - specific antioxidant ( tsa ) in the yeast saccharomyces cerevisiae at the end of the 1980s ( kim et al . , 1988 ) , it turned out that this enzyme was a member of a major and highly expressed superfamily of thiol - dependent peroxidases able to reduce hydrogen peroxide , alky...	inflammation is a pathophysiological response to infection or tissue damage during which high levels of reactive oxygen and nitrogen species are produced by phagocytes to kill microorganisms . reactive oxygen and nitrogen species serve also in the complex regulation of inflammatory processes . recently , it has bee...
annually , more than 7 million patients with chest pain present to emergency departments in the usa . however , of these patients , 75% do not have cardiac - related chest pain.1 evaluation and treatment of these patients imposes a cost of more than us$10 billion on the us health system.2 in iran , a frequent number ...	backgroundmost patients who present to medical centers due to chest pain do not suffer from acute coronary syndromes and do not need to be hospitalized in coronary care units ( ccus ) . this study was done to determine exploitation of resources and cardiovascular outcomes in low - risk patients with chest pain hospit...
in our current study , we found that early exponential growth phase cultures of p. aeruginosa elicited the most robust net release and presence of a functional flagellum was essential for this process . forced contact of immotile p. aeruginosa with pmns restored their ability to trigger maximal net extrusion . p. a...	abstractneutrophil extracellular trap ( net ) formation represents a unique effector function of neutrophils ( pmn ) . the mechanism of net release in response to bacteria is largely unknown . we studied the process by which pseudomonas aeruginosa , an opportunistic pathogen , interacts with primary pmns , and foun...
the majority of breast cancer patients are diagnosed with luminal tumors that are characterized by the expression of estrogen receptors ( er ) and progesterone receptors ( pr ) and the absence or only weak amplification of her2 ( this latter parameter depends on the subclass , whether luminal a or luminal b ) [ 1 , 2 ]...	breast cancer progression is strongly linked to inflammatory processes , aggravating disease course . the impacts of the inflammatory cytokine tnf on breast malignancy are not fully substantiated , and they may be affected by cooperativity between tnf and other protumoral mediators . here , we show that together with...
the identification of genomic regulatory elements is an important but unsolved problem in genome annotation ( 1 ) . of the 5% of mammalian genome that is estimated to be under evolutionary selection pressure , less than a third is coding ( 2,3 ) . the remaining portion is believed to be composed of untranslated regio...	identification and annotation of all the functional elements in the genome , including genes and the regulatory sequences , is a fundamental challenge in genomics and computational biology . since regulatory elements are frequently short and variable , their identification and discovery using computational algorithms...
amyloidosis is particularly difficult to diagnose because the signs and symptoms are subtle . additionally , there are no specific imaging or laboratory tests , except histopathology . although it is considered to be a systemic disorder , a small portion of cases may be localized . a 54-year - old man presented wit...	abstractbackground : amyloidosis is particularly difficult to diagnose because the signs and symptoms are subtle . additionally , there are no specific imaging or laboratory tests , except histopathology . although it is considered to be a systemic disorder , a small portion of cases may be localized.introduction of ...
relapsing polychondritis ( rp ) is a rare autoimmune disease of unknown etiology characterized by recurrent inflammatory episodes primarily affecting the auricular , nasal or laryngotracheal cartilage , as well as the ocular , audiovestibular and cardiovascular systems . the myelodysplastic syndromes ( mds ) are clon...	relapsing polychondritis ( rp ) is a rare multisystem disorder . myelodysplastic syndrome ( mds ) with erythroid hypoplasia / aplasia is a rare form of myelodysplasia . several cases of rp associated with mds have recently been described . however , rp associated with mds with erythroid hypoplasia / aplasia has nev...
about 80% of strokes are ischaemic , resulting from an obstruction of blood flow , while about 15% are due to a primary intracerebral hemorrhage . stroke is one of the leading causes of chronic adult disability and death in western industrialized countries . neurological deficits reflect the location of the tissue ...	stroke is a common and disabling global health - care problem , which is the third most common cause of death and one of the main causes of acquired adult disability in many countries . rehabilitation interventions are a major component of patient care . in the last few years , brain stimulation , mirror therapy , ac...
preoperative complete blood count showed hemoglobin at 8.9 g / dl and hematocrit at 26.5% . the electrocardiography , chest x - ray , and pulmonary function test showed no abnormal findings . after arriving at the or , the patient monitoring system ( polymount philips , usa ) was used to monitor the blood pressure , ...	methemoglobinemia is an uncommon but potentially fatal disorder . most cases have no adverse clinical consequence and require no treatment , but methemoglobinemia is often overlooked as a cause of low oxygen saturation , and often mistaken for the more common causes of hypoxia by anesthesiologists despite simple beds...
leprosy , also known as hansen s disease , is a worldwide health problem , varying from tuberculoid to lepromatous leprosy ( ie , paucibacillary to multibacillary disease ) according to the host immune response . it is caused by mycobacterium leprae , and affects the skin , eyes , and nerves , leading to skin lesions...	backgrounddapsone is described as being active against mycobacterium leprae , hence its role in the treatment of leprosy and related pathologies . despite its therapeutic potential , the low solubility of dapsone in water results in low bioavailability and high microbial resistance . nanoemulsions are pharmaceutical ...
melanogenesis is inherently cytotoxic and uniquely occurs in melanocytic cells ; thus , tyrosine analogs that are tyrosinase substrates are good candidates for melanoma - specific targeting and therapy . n - propionyl and n - acetyl derivatives of 4-s - cysteaminylphenol ( npr- and naccap ) were synthesized and found...	melanogenesis substrate , n - propionyl - cysteaminylphenol ( nprcap ) , is selectively incorporated into melanoma cells and inhibits their growth by producing cytotoxic free radicals . magnetite nanoparticles also disintegrate cancer cells and generate heat shock protein ( hsp ) upon exposure to an alternating magne...
the periodontium is a topographically complex organ consisting of epithelial tissue and soft and mineralized connective tissue . the structures comprising the periodontium include gingiva , cementum , bone and periodontal ligament . several diseases affect the composition and integrity of periodontal structur...	objectivesthe mikania laevigata extract ( mle ) ( popularly known in brazil as " guaco " ) possesses anti - inflammatory properties . in the present study we tested the effects of mle in a periodontitis experimental model in rats . we also investigated possible mechanisms underlying such effects . material an...
over the past year , 3 agents have been approved for the treatment of melanoma by the food and drug administration . these include pegylated interferon -2b for stage iii melanoma , vemurafenib for unresectable or metastatic melanoma with braf v600e mutation , and ipilimumab for unresectable or metastatic melanoma . ...	introductionover the past year , 3 agents have been approved for the treatment of melanoma by the food and drug administration . these include pegylated interferon -2b for stage iii melanoma , vemurafenib for unresectable or metastatic melanoma with braf v600e mutation , and ipilimumab for unresectable or metastatic ...
how did the idea of racial and ethnic difference in lung capacity become so widely accepted such that correction factors are actually programmed into the spirometer ? the notion that black and white lungs differ has a long history dating to the early years of the us slavery - based republic . in his influential notes...	spirometry is the most common lung function test and represents the cornerstone diagnostic and management tool for individuals with chronic respiratory diseases . variability and changing temporal trends in lung function measurements , however , have contributed to the problem of standardizing spirometry , especially...
according to ancient medical and veterinary literature , native information of herdsmen regarding the usage of medicinal plants in animal and human disorders is described as ethnoveterinary medicine ( evm ) . evm considers that traditional practices of veterinary medicine are legitimate and seeks to validate them . ...	this paper describes a selection of the ethnoveterinary medicines used for herd dogs in the southern regions of ilam province , iran . traditional botanical medicine is the primary mode of healthcare for most of the rural population in ilam province . in this study , a questionnaire was distributed among 45 residen...
the discovery of intra - vascular foreign bodies is increasing and their associated danger is well recognized . endovascular retrieval of intravascular foreign bodies offers a high success rate with minimal morbidity and mortality . a variety of tools are available to the interventionist to aid in foreign body extr...	highlightsendovascular techniques to retrieve intra - vascular foreign bodies are a necessary component of the vascular surgeon s skill set.endovascular retrieval of intravascular foreign bodies is minimally invasive , relatively simple , and carries minimal morbidity compared to conventional open surgical techniques.i...
topical anesthesia is becoming increasingly widely accepted and has become a well - established technique for use in phacoemulisification.1 a number of previous studies that have evaluated topical versus needle block anesthesia have shown no significant difference in patient satisfaction.2,3 unlike phacoemulsification ...	purposeto evaluate the effectiveness of subconjunctival anesthesia as compared to retrobulbar anesthesia for pain control during manual small - incision cataract surgery ( msics ) performed by third - year residents.designa randomized , controlled trial.patients and methodsa total of 150 patients undergoing routine cat...
new , large genomic data sets are providing more in - depth insights into the diagnosis and treatment of disease . in the past decade , new and innovative methods have continued to add value to the underlying data and uncover the secrets of the genome . visual data inspection by experienced researchers is an import...	the name alview is a contraction of the term alignment viewer . alview is a compiled to native architecture software tool for visualizing the alignment of sequencing data . inputs are files of short - read sequences aligned to a reference genome in the sam / bam format and files containing reference genome data ....
bentall and de bono introduced the initial standardized procedure for aortic root replacement ( arr ) in 1968 , and since then , technical improvements , surgical modifications , and development of new materials during the last 3 decades have made this procedure safer and more reproducible . in the current era , repo...	backgroundgeneralization of standardized surgical techniques to treat aortic valve ( av ) and aortic root diseases has benefited large numbers of patients . as a consequence of the proliferation of patients receiving aortic root surgeries , surgeons are more frequently challenged by reoperative aortic root procedures...
in the present issue of critical care , noveanu and colleagues evaluated brain natriuretic peptide ( bnp ) and n - terminal prohormone brain natriuretic peptide ( nt - probnp ) serial measurements as predictive of 30-day and 1-year mortality and readmission in patients admitted to the emergency department for acute dec...	acute decompensated heart failure is one of the most important causes of hospitalisation worldwide . natriuretic peptides have shown their usefulness in the diagnosis and management of heart failure . their variations during hospitalisation also appear useful to predict outcomes . in particular , data from the li...
carcinoma of the thyroid gland is the most common endocrine malignancy , accounting in the usa for example for 95% of endocrine tumors . over the last 3 decades the incidence of well - differentiated thyroid cancer ( tc ) increased from 4.9 per 100 000 in 1975 to 14.3 per 100 000 in 2009 . in china , the standardized...	backgroundthe aim of this study was to investigate the accuracy of contrast - enhanced ultrasound ( ceus ) enhancement patterns in the assessment of thyroid nodules.material/methodsa total of 158 patients with suspected thyroid cancer underwent conventional ultrasound ( us ) and ceus examinations . the contrast enhan...
a 63-year - old woman with chronic atrial fibrillation treated with warfarin was admitted to emergency for coma and complete vertical gaze palsy . investigations : brain ct and mri , echo - colour doppler sonography of the supraaortic vessels , angio - ct of the intracranial vessels , eeg , transesophageal echocardio...	backgrounda 63-year - old woman with chronic atrial fibrillation treated with warfarin was admitted to emergency for coma and complete vertical gaze palsy . investigations : brain ct and mri , echo - colour doppler sonography of the supraaortic vessels , angio - ct of the intracranial vessels , eeg , transesophageal ...
several epidemiological studies have confirmed the close relationship between diabetes and obesity ; more than 80% of patients with type 2 diabetes are estimated to be overweight or obese . as the prevalence of obesity increases , the risk of type 2 diabetes is likely to increase . between 1980 and 1990 , the majority ...	type 2 diabetes and obesity have a complex relationship ; obesity is linked to insulin resistance , the precursor to type 2 diabetes . the management of obesity is an important method to delay onset of diabetes and improve the glycemic durability of antidiabetic agents . however , insulin and some of the oral hypog...
the first symptom of soft rot on apple fruit was a water - soaked appearance to the affected tissue . the diseased parts later disintegrated into a mushy mass of disorganized cells that sloughed off . white mycelia formed on infection sites of apples and gradually covered the fruit with tufted whisker - like gray s...	soft rot in apple caused by rhizopus oryzae was found for the first time in korea . a detailed description of the specimen is given along with its internal transcribed spacer rdna sequence . the fungus was identified as rhizopus oryzae based on the mycological characteristics , molecular data , and pathogenicity te...
hematohidrosis is known to be precipitated by stress , strain , or any sort of exertion , and it may occur in individuals with underlying bleeding disorders . it may occur in individuals suffering from extreme levels of stress . around the sweat glands , there are multiple blood vessels in a net - like form , which c...	hematohidrosis is a very rare condition in which an individual sweats blood . it may occur in an individual who is suffering from extreme levels of stress . various causative factors have been suggested like component of systemic disease , vicarious menstruation , excessive exertion , psychogenic , and unknown caus...
our research is approved by the ethics committee of medical college hospitals , kolkata , west bengal , india . each of the authors for preparing this case report , dr . kallol dasbaksi ( corresponding author ) , dr . plaban mukherjee have contributed to the study concept or design , data collection , data an...	highlightsthis case presentation , emphasizes the typical manifestations of hepatic but associated asymptomatic pericardial hcs.hepatic hydatid cyst presenting as a painless abdominal lump preceded painful presentation for a few months.asymptomatic pericardial hydatid cyst could have presented with pericardial tamponad...
necrobiotic xanthogranuloma ( nxg ) was first described as a separate entity by kossard and winkelmann in 1980 . the disease is characterized by multiple , plaque- like , yellow - brown lesions , with a predilection for the periorbital area ( spectacle - like distribution ) . about 100 cases have been reported in w...	necrobiotic xanthogranuloma ( nxg ) is a very rare , progressive variant of non - langerhans cell histiocytosis . it is known to be associated with multisystem involvement and paraproteinemias . a 65-year - old female presented with chronic , slowly growing , asymptomatic periorbital nodules . the lesions had recur...
	the nasal cavity is susceptible to chemically induced injury as a result of exposure to inhaled irritants . some responses of the nasal mucosa to inhaled toxicants are species specific . these species - related differences in response may be due to variations in structural , physiologic , and biochemical factors , ...
the risk of rupture approximates 50% , most of which occur in the second trimester . was then performed with fetal intracardiac potassium chloride and intraplacental methotrexate . magnetic resonance imaging ( mri ) of the pelvis was obtained . while surgical resection of a rudimentary horn pregnancy is necessary ,...	background : pregnancy within a noncommunicating rudimentary horn is a known complication of unicornuate uterus . the risk of rupture approximates 50% , most of which occur in the second trimester.case:a rudimentary horn pregnancy was discovered at 8 weeks gestation . medical termination was then performed with fet...
the louisiana state university health care services division ( lsuhcsd ) operates seven public hospitals and affiliated clinics in louisiana that provide quality medical care to the residents of louisiana regardless of their income or insurance coverage ( 1924 ) . overall , lsuhcsd facilities have served ~1.6 million...	objectivediabetes confers a very high risk of lower - extremity amputation ( lea ) ; however , few studies have assessed whether blood glucose control can reduce lea risk among patients with diabetes , especially in practice settings where low - income patients predominate.research design and methodswe performed a pros...
magnesium ( mg ) is an important cofactor for the enzymes that are involved in carbohydrate metabolism : an important role of mg in insulin action has been reported [ 1 , 2 ] ; low serum and intracellular mg ( [ mg]i ) concentrations are associated with insulin resistance , impaired glucose tolerance , and decreased in...	magnesium deficiency in pregnancy frequently occurs because of inadequate or low intake of magnesium . magnesium deficiency during pregnancy can induce not only maternal and fetal nutritional problems , but also consequences that might last in offspring throughout life . many epidemiological studies have disclosed ...
the continuous monitoring and audit of clinical practice is an essential part of making improvements in medical science and enhancing patient care . this is true also in the management of neurosurgical cases , but no validated comparative tool was available until 2008 , when the physiological and operative severity s...	background and aims : continuous audit of clinical practice is an essential part of making improvements in medicine and enhancing patient care . validated tools are needed to gather evidence for comparisons . recently , physiological and operative severity score for the enumeration of mortality and morbidity ( possum...
image - guided radiation therapy ( igrt ) during patient set - up prior to treatment delivery allows the patient to be positioned as closely as possible to the expected irradiation position . several recent igrt techniques include fan - beam ct [ 13 ] , ct - on - rails , cone - beam ct ( cbct ) [ 56 ] , electronic po...	a linear accelerator vendor and the aapm tg-142 report propose that quality assurance testing for image - guided devices such megavoltage cone - beam ct ( mv - cbct ) be conducted on a monthly basis . in clinical settings , however , unpredictable errors such as image artifacts can occur even when quality assurance r...
the toxin a- and toxin b - specific recombination vectors pjir3051 and pjir3050 were constructed by cloning a 566 bp tcda ( accession m30307 ) pcr product ( nt 10711637 ) and the equivalent tcdb ( accession x53138 ) region , respectively , into the shuttle vector pjir1456 ( accession u90554 ) . these plasmids were tr...	clostridium difficile is the leading cause of infectious diarrhea in hospitals worldwide , because of its virulence , spore - forming ability and persistence1,2 . c. difficile - associated diseases ( cdad ) are induced by antibiotic treatment or disruption of the normal gastrointestinal flora3,4 . recently , morbid...
gastrointestinal stromal tumours ( gists ) are the most frequent mesenchymal tumours of the digestive tract , derived from the cajal interstitial cells . they are characterised by the presence of a gain - of - function mutation of the kit or pdgfra oncogenes . their incidence remains low , around 520 per million in...	gastrointestinal stromal tumours ( gists ) are mesenchymal tumours of the digestive tract , derived from cajal interstitial cells . bone metastases are very rare , and there is no consensus regarding their treatment . here , we present the unusual case of a 66-year - old man with a gastric gist with synchronous bone ...
	previous studies on the reproductive toxicity of boric acid have indicated that male rodents suffer testicular atrophy after treatment . there were , however , no studies of the potential effects on female fertility or on the neonate . in addition , no study described the development of the testicular lesion , thou...
alcohol consumption and abuse can have a variety of cutaneous manifestationsfamiliarization with the spectrum of cutaneous manifestations of alcohol abuse and alcoholic liver disease allows for early detection and treatment in an attempt to minimize the medical consequences . alcohol consumption and abuse can have a ...	background : chronic alcohol intake impacts skin directly , through organ dysfunction or by modifying preexisting dermatoses . however , dermatoses afflicting chronic alcoholics figure in a few studies only.aim:this study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum / duration o...
candida albicans is the most common fungal pathogen causing invasive and bloodstream infections in immunocompromised patients , although in recent years , several non - albicans species and other yeasts have also emerged as major opportunistic pathogens ( 1,2 ) . studies in the us identify candida glabrata as the sec...	the candida genome database ( cgd , http://www.candidagenome.org/ ) is an internet - based resource that provides centralized access to genomic sequence data and manually curated functional information about genes and proteins of the fungal pathogen candida albicans and other candida species . as the scope of candida r...
urinary incontinence affects up to 50% of women , resulting in a significant medical , social , and economic burden . the annual direct costs of incontinence in the united states were estimated to be more than $ 16 billion . among women with incontinence , 50% to 80% are identified as having stress urinary incontin...	purposewe compared outcomes of the u- and h - type approaches of the tension - free vaginal tape ( tvt)-secur procedure for the treatment of female stress urinary incontinence ( sui).materials and methodsfrom march 2007 to july 2008 , 115 women with sui underwent tvt - secur by a single surgeon . patients were random...
this study was approved by the ethics committee of the armed forces medical command , which waived the requirement of informed patients consent for this retrospective study . from july 18 to july 30 , 2009 , 18 out of 57 patients who presented with acute febrile respiratory illness ( fever of 38 or higher , and/or a co...	objectiveto describe detailed clinical and radiological features of the pandemic h1n1 2009 influenza viral infection among healthy young males in a semi - closed institutionalized setting.materials and methodsa total of 18 patients confirmed with the pandemic h1n1 2009 influenza virus infection from july 18 to july 30 ...
briefly , we injected 12 ng of morpholino into 4-cell stage x. laevis embryos to knock down rfx2 expression ; the morpholino sequence has been previously reported . we then prepared 100 animal caps ( ectodermal explants of stage 10 x. laevis embryos , dissected with forceps ) , both for control samples and rfx2 m...	recently , using the frog xenopus laevis as a model system , we showed that the transcription factor rfx2 coordinates many genes involved in ciliogenesis and cell movement in multiciliated cells ( chung et al . , 2014 ) . to our knowledge , it was the first paper to utilize the genomic resources , including genome se...
atrial fibrillation ( af ) with progressive atrial dilation combined with inadequate anticoagulation exhibits a high risk of thromboembolic events . we present the unusual case of a ball thrombus originating from the left atrium ( la ) with remaining continuity to the left atrial appendage ( laa ) causing syncope and...	few cases of a left atrial thrombus without mitral valve disease have been reported . we present an unusual case in which a patient presented to the emergency department with syncope and acute cerebral ischemia caused by a ball thrombus originating from the left atrium ( la ) . an emergency bedside echocardiogram s...
gynecologic malignancies , including cervical and vaginal cancers , often require a multidisciplinary approach that combines radiation , chemotherapy and/or surgery . imaging modalities that can accurately assess the extent of the disease and the effect of treatments have become an integral component in evaluating th...	objectivethe role of f-18-fluorothymidine ( flt ) pet - ct imaging in the evaluation of gynecologic cancers has not been established . we sought to evaluate ( flt ) pet - ct imaging in gynecologic cancers by comparing standard uptake values ( suvs ) of flt with f-18-fluorodeoxyglucose ( fdg ) pet in the primary tumor...
recent years have seen growing numbers of cervical disc replacements and fusions due to improved surgical techniques.1,2,3 diagnostics and differential diagnostics have been highly standardized;4 however , recurrent cervical symptoms frequently occur.5 possible vertebrogenic causes lie within the treated or adjacent se...	recurrent cervical symptoms frequently occur after cervical disc replacement and fusion . to date , no algorithm for the diagnostic assessment of these symptoms has been established . we present a case report and review of the literature to illustrate the need for interdisciplinary diagnostics in recurrent cervicobra...
stroke is the second highest cause of death in the world and the main cause of disability in people in productive ages . in indonesia , the average age of stroke patients is 58.8 years old and stroke is the leading cause of high mortality rate in people above 50 years old . statistics of heart disease and stroke201...	carotid intima media thickness ( cimt ) is clearly associated with atherosclerosis . studies in ischemic stroke patients reveal that there is a significant association between cimt with monocyte chemoattractant protein-1 ( mcp-1 ) and osteopontin ( opn ) promoter polymorphism . this research aims to explain the eff...
, early evidence characterizing spontaneous physical activity in children has shown that children take frequent ( 83 to 89 bouts per hour ) , short - duration ( mean duration of 20 to 21 s ) bouts of movement of variable but mostly low intensity , interspersed by comparatively long intervals of nonactive time [ 2 , 3 ...	physical activity and sedentary behavior are central components of lifetime weight control ; however , our understanding of dimensions of these behaviors in childhood is limited . this study investigated free - living activity pattern characteristics and the individual variability of these characteristics in 84 lean ...
multidisciplinary therapeutic techniques are employed in the rehabilitation of patients with advanced disease of the stomatognathic and craniofacial structures [ 1 , 2 ] . although surgical intervention can halt the disease process , prosthodontic rehabilitation is often needed to restore mastication , speech , and e...	current materials used for maxillofacial prostheses are far from ideal and there is a need for novel improved materials which mimic as close as possible the natural behavior of facial soft tissues . this study aimed to evaluate the effect of adding different concentrations of surface treated silicon dioxide nanoparti...
	using a scanning tunneling and atomic force microscope combined with in - vacuum atomic hydrogen cleaning we demonstrate stable scanning tunneling spectroscopy ( sts ) with nanoscale resolution on electrically active nanowire devices in the common lateral configuration . we use this method to map out the surf...
novel biological agents , including anti - epidermal growth factor receptor ( egfr ) , anti - vegf targeting therapies , and small - molecule multikinase inhibitors , have recently changed the standard of care of metastatic colorectal cancer ( mcrc ) patients . while the use of positive predictive biomarkers for biol...	as the knowledge on cancer genetic alterations progresses , it fosters the need for more personalized therapeutic intervention in modern cancer management . recently , mutations in kras , braf , and pik3ca genes have emerged as important mechanisms of resistance to egfr - targeted therapy in metastatic colorectal can...
primary hyperparathyroidism ( php ) is an endocrine system disease , mostly seen in older population . the cause of php is solitary parathyroid adenoma ( pa ) in 80 - 85% of the cases . number of imaging techniques have been used for preoperative localization of parathyroid adenoma including technetium-99 m labelle...	background : the purpose of this study was to evaluate the value of tc-99 m pertechnetate planar , dual - phase mibi and mibi - spect images in the determination and localization of parathyroid lesions.materials and methods : in this study , 38 patients who underwent operation for primary hyperparathyroidism were inclu...
the database from 2 randomized controlled phase iii trials comparing vancomycin with fidaxomicin for the treatment of cdi was used to assess the predictive value of fever , leukocyte count , and serum creatinine level [ 9 , 10 ] . patients were recruited in the united states , canada , and europe ( clinicaltrials.gov...	nonsevere clostridium difficile infection ( cdi ) and severe cdi , which carries a higher risk than nonsevere cdi for treatment failure and cdi recurrence , are difficult to distinguish at the time of diagnosis . to investigate the prognostic value of 3 markers of severe cdi suggested by recent guidelines ( fever , leu...
supramolecular self - assembly represents a key technology for the spontaneous construction of nanoarchitectures and for the fabrication of materials with enhanced physical and chemical properties [ 14 ] . in addition , a significant asset of supramolecular self - assemblies rests on their reversible formation , than...	here we investigate the supramolecular polymerizations of two lipophilic guanosine derivatives in chloroform by light scattering technique and tem experiments . the obtained data reveal the presence of several levels of organization due to the hierarchical self - assembly of the guanosine units in ribbons that in tur...
for more than two decades , the functional role of ca - activated cl channels ( caccs ) in vascular smooth muscle cells ( vsmcs ) has been actively investigated . this research focus was initiated by the first demonstration in 1987 of a ca - activated cl current ( icl(ca ) ) in smooth muscle cells , which naturall...	the presence of ca2 + -activated cl currents ( icl(ca ) ) in vascular smooth muscle cells ( vsmcs ) is well established . icl(ca ) are supposedly important for arterial contraction by linking changes in [ ca2+]i and membrane depolarization . bestrophins and some members of the tmem16 protein family were recently as...
a 35-year - old man presented with a 7.0 cm anterior mediastinal mass on a chest radiograph during a routine medical evaluation at an outside hospital . the patient was transferred to the department of thoracic and cardiovascular surgery for further evaluation and treatment . the patient did not present with any sp...	thymoma is the most common neoplasm of the anterior mediastinum and has malignant potential . germ cell tumors ( gcts ) found in the anterior mediastinum are usually benign , and malignant gcts , such as seminomas , are rare . histologically , mediastinal seminoma is indistinguishable from testicular seminoma excep...
the causes of posterior shoulder dislocations are usually a strong traumatic event or a sudden violent internal rotatory muscles contraction such as what may happen during a convulsive crisis or electrocution [ 13 ] . in most of the cases , the dislocation is subacromial and posterosuperior ; the subspinatus and ...	posterior dislocation of the shoulder is an unfrequent event that often occurs as a consequence of a direct trauma or epileptic crisis . frequently the posterior dislocations are misunderstood , so they become chronic lesions . we reported a case of an acute posterior left shoulder dislocation with lesser tuberosit...
the data presented here were obtained from an ongoing prospective multicentre clinical study to search for biomarkers of periodontal disease progression . a consecutive sample of 329 participants was recruited between january 2012 and april 2015 at four centres in the united states : the forsyth institute ( cambridge...	abstractaimthe goal of this study was to identify progressing periodontal sites by applying linear mixed models ( lmm ) to longitudinal measurements of clinical attachment loss ( cal).methodsninetythree periodontally healthy and 236 periodontitis subjects had their cal measured bimonthly for 12 months . the proporti...
gardner 's syndrome ( gs ) is an autosomal dominant disorder localized to a small region on the long arm of chromosome 5 ( 5q21 - 22).1,2,3 menzel first described adenomatosis of the colon in 1721 , and in 1863 , cripps discovered the heredity of colon polyposis and termed it familial adenomatosis.4 devic and bussy in ...	gardner 's syndrome is a variant of familial adenomatosis polyposis ( fap ) with a triad consisting of polyps of the colon , multiple osteomas and surface tumors of soft and hard tissue . the intestinal polyps have a % 100 risk of undergoing malignant transformation , therefore early identification of this disease is...
on december 8 , 2003 , as president george w. bush prepared to sign the mma into law , he took a moment to look back over the work that went into the legislation . with the medicare act of 2003 , our government is finally bringing prescription drug coverage to the seniors of america , he said . the challenges fac...	this article describes the lengthy background and debate leading up to the passage of the medicare prescription drug , improvement and modernization act of 2003 ( mma ) . full implementation of the prescription drug aspect of the law will not be completed for some time , and final assessment of its impact awaits a hi...
it is a symptom that expresses a disorder in the transport of food and endogenous secretions ( saliva ) through the upper digestive tract . oropharyngeal dysphagia ( od ) is a more anatomically restricted term referred to alterations in the transfer of the bolus from the mouth to the esophagus ( that means , in bolus...	on considering a function - preserving treatment for laryngeal and hypopharyngeal cancer , swallowing is a capital issue . for most of the patients , achieving an effective and safe deglutition will mark the difference between a functional and a dysfunctional outcome . we present an overview of the management of dy...
diabetic nephropathy ( dn ) is one of the most devastating microvascular complications of diabetes , which remains the most common cause for end stage renal disease ( esrd ) . the prevalence of diabetes and the patients suffering from diabetic microvascular complications is increasing worldwide . nearly one - third...	background . hyperglycemia plays a pivotal role in the development of diabetic nephropathy ( dn ) and may be related to epigenetic metabolic memory . one of the most crucial epigenetic mechanisms is histone modification , which is associated with the expression of a fibrosis factor in vascular injury . aim .in th...
obesity , influenced by environmental and genetic factors , is one of the important factors in the etiology of metabolic syndrome , cardiovascular disease ( cvd ) , and cancer [ 13 ] . obesity is related to increased level of inflammatory markers such as crp ( c - reactive protein ) that are associated with metabolic...	background . adiponectin , an adipokine secreted from adipose tissue , has antiobesity , anti - insulin resistance , and anticancer roles . the present study aimed to review the epidemiologic evidence about the association between adiponectin and cancers . method . we searched in pubmed from 2002 to october 2011 ...
this study was approved by institutional review boards ( irb ) of the national centre of excellence in molecular biology and the combined neuroscience ( cns ) irb at the national institutes of health . ophthalmological examinations were performed at the layton rehmatullah benevolent trust hospital in lahore , pakista...	purposeto identify the genetic origins of autosomal recessive congenital cataracts ( arcc ) in the pakistani population.methodsbased on the hypothesis that most arcc patients in consanguineous families in the punjab areas of pakistan should be homozygous for causative mutations , affected individuals were screened for ...
in our case series , we analyzed 14 patients from our mri and clinical database admitted between 2011 and 2014 with csf - confirmed diagnosis of aseptic meningitis . clinical data including age , sex , presenting symptoms and clinical course , duration of hospitalization , medication , and neurologic status at discha...	objective : to investigate the blood - csf barrier ( bcsfb ) dysfunction in aseptic meningitis.methods:in our case series of 14 patients with acute aseptic meningitis , we compared mri characteristics with csf findings.results:contrast enhancement in the sulcal space in a leptomeningeal pattern was visualized in 7 pati...
neuromyelitis optica ( nmo ) is an inflammatory disorder restricted to the spinal cord and optic nerves . contrary to multiple sclerosis ( ms ) , relapses of nmo are often strikingly severe and most nmo patients present stepwise neurological impairments . nmo treatments are aimed to prevent the relapses with the ad...	background . neuromyelitis optica ( nmo ) attacks are poorly controlled by steroids and evolve in stepwise neurological impairments . assuming the strong humoral response underlying nmo attacks , plasma exchange ( plex ) is an appropriate technique in severe nmo attacks . objective . presenting an up - to - date re...
more than a decade ago , the unusual catalytic activity of the dna repair enzyme alkb was demonstrated by sedgwick , falnes , and co - workers , whereby oxygen is added to foreign , unnatural carbon atoms attached to nitrogen bases , leading to the liberation of an aldehyde and restoration of the canonical pu...	the alkb enzyme is an fe(ii)- and -ketoglutarate - dependent dioxygenase that repairs dna alkyl lesions by a direct reversal of damage mechanism as part of the adaptive response in e. coli . the reported substrate scope of alkb includes simple dna alkyl adducts , such as 1-methyladenine , 3-methylcytosine , 3...
historically , the sweetness of urine and other body fluids in diabetic patients suggested that glucose had an important role in the physiopathology of this common disease . thus , glucose metabolism and the insulin - glucose axis were the leading fields for scientific investigations . to emphasize this con...	the dysregulation of the insulin - glucose axis represents the crucial event in insulin resistance syndrome . insulin resistance increases atherogenesis and atherosclerotic plaque instability by inducing proinflammatory activities on vascular and immune cells . this condition characterizes several diseases , such a...
zinc is an essential trace element for living organisms , because it is required for the catalytic activity of numerous metalloenzymes ( 1 ) and can also serve as a key structural component of a large number of zinc - dependent proteins 2 . , 3 .. zinc homeostasis in the cells , therefore , is achieved through the co...	zip ( zrt / irt - like protein ) and cdf ( cation diffusion facilitator ) are two large metal transporter families mainly transporting zinc into and out of the cytosol . several zip and cdf transporters have been characterized in mammals and various model organisms , such as yeast , nematode , fruit fly , and zebrafish...
lymphocytic plasmacytic enteritis ( lpe ) , a chronic enteropathie , is the most frequently described type of inflammatory bowel disease in dogs . lpe is recognized as one of the most common causes of chronic vomiting and diarrhoea . the name of this disorder refers to the population of inflammatory cells present i...	distended lacteals , described as expanded white villi in duodenum , are strongly indicative of primary intestinal lymphangiectasia . in the present study , we evaluated the significance of white spots present in the duodenal mucosa of dogs with lymphocytic plasmacytic enteritis ( lpe ) . fifty dogs with lpe were inc...
the united states maintains a national network of hospitals and clinics , using a single - payer , single - employer model , dedicated to providing care to former members of the united states armed forces . collectively , this network is known as the veterans health administration ( vha ) , which is a subsidiary of t...	objective(1 ) to determine the effects of adding a provider in triage on average length of stay ( los ) and proportion of patients with > 6 h los . ( 2 ) to assess the accuracy of computer simulation in predicting the magnitude of such effects on these metrics.methodsa group - level quasi - experimental trial comparin...
health - related professionals are at high risk of job burnout which will in turn lead to effects on health services provision . the present study was conducted to define job burnout and its association with personal characteristics among the midwives working in isfahan , iran . this descriptive correlational study...	background : health - related professionals are at high risk of job burnout which will in turn lead to effects on health services provision . the present study was conducted to define job burnout and its association with personal characteristics among the midwives working in isfahan , iran.materials and methods : this ...

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.