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in spite of the vast advances made by medical science in cancer treatment , infections remain a major cause of morbidity and mortality in patients diagnosed with cancer .
the cancer patient is immunocompromised because of the nature of the disease itself and also due to interventions in the form of chemotherapy etc .... | introduction : this increased risk of bacterial infections in the cancer patient is further compounded by the rising trends of antibiotic resistance in commonly implicated organisms . in the indian setting
this is particularly true in case of gram negative bacilli such as escherichia coli , klebsiella pneumoniae and ... |
fibrous dysplasia is not hereditary in nature and it caused by mutation in the gnas1 ( guanine nucleotide binding protein , alpha stimulating activity polypeptide ) gene ( 20q13.2 ) and this gene encodes a g - protein which results in overproduction of camp in the affected tissues .
furthermore , there is increased t... | fibrous dysplasia ( fd ) is a benign intramedullary fibro - osseous lesion .
fd is a bone developmental anomaly characterized by replacement of normal bone and marrow bone by fibrous tissue .
it involves any of the bones as single lesion ( monostotic ) or in multiple bone lesions ( polyostotic ) or all of the skele... |
a 65-year - old woman was referred to our department because of a recently diagnosed left atrial ( la ) mass .
she presented with a five - month history of fever , malaise , and myalgia and had been diagnosed with ventricular septal defect ( vsd ) two years earlier . on physical examination ,
two - dimensional tran... | cardiac myxomas are the most common primary benign tumors of uncertain etiology
. they usually present as polypoid or oval - shaped masses projecting into a heart chamber from the interatrial septum and have a soft , gelatinous consistency without a cystic structure .
we report a case of left atrial myxoma with a s... |
between june 2000 and may 2008 , 69 cases of an open reduction and internal fixation with a plate were performed for clavicle midshaft fractures . of them ,
41 patients , who could have been followed until bony union was achieved , were reviewed retrospectively .
the operative indications were fractures involving ... | backgroundto compare the outcomes of reconstruction plate and reconstruction locking compression plate ( lcp ) for the treatment of clavicle midshaft fractures.methodsforty one patients with a clavicle midshaft fracture were treated by internal fixation with a reconstruction plate ( 19 patients ) or reconstruction lcp ... |
many diseases of high public health importance , such as type 2 diabetes and metabolic syndrome , are profoundly influenced by obesity status ( 1 ) .
however , individuals with a similar body mass index ( bmi ) can exhibit substantially different metabolic profiles for glucose tolerance , lipids , and blood pressure ... | obese subjects with a similar body mass index ( bmi ) exhibit substantial heterogeneity in gluco- and cardio - metabolic heath phenotypes .
however , defining genes that underlie the heterogeneity of metabolic features among obese individuals and determining metabolically healthy and unhealthy phenotypes remain chall... |
chronic obstructive pulmonary disease ( copd ) is a disease characterized by airflow limitation that is not fully reversible ( 1 ) .
copd is a major health problem worldwide , with a high rate of occurrence , and high costs with its management .
it is the fourth leading cause of death in the world and the economic ... | a genome - wide association study has identified the 15q25 region as being associated with the risk of chronic obstructive pulmonary disease ( copd ) in caucasians .
this study intended as a confirmatory assessment of this association in a korean population .
the rs6495309c > t polymorphism in the promoter of nicot... |
1 . digital photography is a fundamental art in the day to day practice of a
dermatologist .
the main issue in most of the clinical photographs is the lack of good , reproducible and consistent digital images .
digital photography is a fundamental art in the day to day practice of a dermatologist .
but the main... | photography has proven to be a valuable tool in the field of dermatology .
the major reason for poor photographs is the inability to produce comparable images in the subsequent follow ups .
combining digital photography with image processing software analysis brings consistency in tracking serial images .
digital... |
human immunodeficiency virus ( hiv)/acquired immune deficiency syndrome ( aids ) affects 22.4 million to 28 million people and is responsible for the deaths of 1.4 million in the sub - saharan african countries alone.1 ethiopia is home to approximately 800,000 patients with hiv / aids , and the prevalence of hiv / aids... | backgroundhuman immunodeficiency virus ( hiv)/acquired immune deficiency syndrome ( aids ) is one of the greatest public health problems of sub - saharan african countries .
consistent condom use , among others , remains the most effective barrier method against hiv transmission .
however , existing reports on freq... |
with an aging society , the incidence of degenerative lumbar spinal canal stenosis ( lscs ) has been increasing in japan .
various operative techniques are available for treating lscs , and minimally invasive surgery has recently been proposed including microscopic surgery and endoscopic surgery . in this report , we... | study design : technical note.objectives:to show microsurgical technique , considering the meticulous anatomy of the ligamentum flavum ( lf).background : different methods are available for treating lumbar spinal canal stenosis ( lscs ) .
a minimally invasive surgery , namely , space shuttle laminotomy , has recently... |
fibromyalgia ( fm ) is a chronic pain syndrome with symptoms that include widespread pain , fatigue , sleep disruption , and cognitive impairment .
fm is estimated to affect 2%8% of the population13 and is often comorbid with related conditions such as irritable bowel syndrome ( ibs ) and chronic fatigue syndrome .
... | objectiveinfections and other stressors have been implicated in the development of fibromyalgia .
we hypothesized that these stressors could result in recurrent reactivations of latent herpes virus infections , which could lead to the development of fibromyalgia .
this study evaluated a famciclovir + celecoxib drug... |
the open window theory implies that there is altered immunity following an acute bout of exercise , which lasts from three to 72 hours after exercise depending on the parameter measured .
according to the theory , there is an increased risk of contracting infectious diseases after physical exercise .
the j means ... | the open window theory indicates altered immunity 3 to 72 hours after exercise .
the j - curve describes the risk of illness in response to exercise . the aim of this study was to examine the secretion of proinflammatory and anti - inflammatory cytokines before and after long - term strenuous exercise .
fourteen ma... |
to date , only one study has investigated the association between aging and cancer by an extensive examination of the expression profiling of aging - related genes in various human tumor types .
i have identified 3,359 human aging - related genes on the basis of 10 relevant publications ; these genes are involved in ... | the emergence of a huge volume of omics data enables a computational approach to the investigation of the biology of cancer .
the cancer informatics approach is a useful supplement to the traditional experimental approach .
i reviewed several reports that used a bioinformatics approach to analyze the associations... |
alpha-1-antitrypsin ( aat ) deficiency , an autosomal recessive disorder , is caused by inheritance of two severe deficient alleles of serpin 1 ( located on chromosome 14q31 - 32 ) encoding aat .
the reactive loop site in the -sheet contains the neutrophil elastase binding site with a methionine residue . the proteas... | alpha-1-antitrypsin ( aat ) deficiency is a rare genetic disorder characterized by hepatitis in neonates , childhood and adulthood ( protease inhibitor ( pi)*zz ) and emphysema with or without hepatitis ( pi*zz)/(pi*ss , sz or null ) in adulthood .
we report the case of a female neonate born at 40 weeks of gestation... |
microencapsulation is a useful method for prolonging drug release from dosage form and reducing adverse effect .
recently , dosage forms that can precisely control the release rates and target drugs specific body site have made an enormous impact in the formulation and development of novel drug delivery system .
mi... | the aim of the current study was to formulate and optimize the formulation on the basis of in vitro performance of microsphere .
a 32 full factorial design was employed to study the effect of independent variables , polymer - to - drug ratio ( x1 ) and stirring speed ( x2 ) , on dependent variables , encapsulation ef... |
the multiple - dose pharmacokinetics of fe 999049 have been described , accounting for endogenous follicle - stimulating hormone ( fsh ) levels.exposure to fe 999049 was influenced by body weight , which may be a potential factor for individualised dosing recommendations.endogenous fsh levels were influenced by proge... | objectivethe aim of this study was to characterise the population pharmacokinetics of fe 999049 , a novel recombinant human follicle - stimulating hormone ( fsh ) , after multiple dosing in healthy women , taking into account endogenous fsh levels and the reproductive hormone dynamics.methodslongitudinal measurements o... |
prognosis of advanced or metastatic pancreatic adenocarcinoma is poor , with a median overall survival between 6.8 and 11 months for all histological types .
herein we report a case of a patient treated by the combination of gemcitabine plus oxaliplatin ( gemox regimen ) with a complete radiological response .
a 50... | pancreatic acinar cell carcinoma ( acc ) is a rare entity .
herein we present the case of a 50-year - old male patient with an unlimited mass on the pancreatic corpus and tail with peripancreatic effusion and multiple metastases in the liver and spleen .
a liver biopsy showed a pancreatic acc .
the patient receiv... |
children afflicted with nephrotic syndrome lose proteins to urine , resulting in hypoproteinemia and generalized edema .
idiopathic nephrotic syndrome occurs in two or more children out of 100,000 and is the most common chronic glomerular disease in children .
many patients have minimal change nephrotic syndrome ... | in the past 10 years , many reports have suggested that rituximab , a chimeric anti - cd20 monoclonal antibody , is effective for children with complicated , frequently relapsing or steroid - dependent nephrotic syndrome ( frns / sdns ) .
however , those reports were case reports , case series , retrospective survey... |
bipolar disorder is estimated to affect 3%7% of population ( angst 1998 ; kessler et al 2005 ) . numerous us fda - approved treatment options exist for the treatment of manic phase of bipolar disorder , including lithium , valproic acid and all 5 atypical antipsychotics
olanzapine , risperidone , quetiapine , ziprasi... | the essential features of bipolar affective disorder involve the cyclical occurrence of high ( manic or hypomanic episodes ) and low mood states .
depressive episodes in both bipolar i and ii disorder are more numerous and last for longer duration than either manic or hypomanic episodes .
in addition depressive epi... |
although several techniques have been proposed to achieve consistent and predictable root coverage , by some estimates , the average percentage of covered root surfaces resulting from different procedures performed under varying clinical conditions varies from 56% to 97.8%.[36 ] thus , treatment of buccal recession rem... | the aim of the randomized controlled single blind study is to evaluate the treatment of miller 's class ii gingival recessions by coronally positioned flap ( cpf ) with or without acellular dermal matrix allograft ( adma ) .
ten patients with 20 sites with maxillary bilateral miller 's class ii facial recession defec... |
chemical synthesis remains a cornerstone of the enterprise of preparing small molecule active pharmaceutical ingredients ( apis ) .
advances in the field of chemical synthesis continue to be benchmarked by the methods and strategies for the preparation of complex natural products , which , more effectively than any o... | general strategies for the chemical synthesis of organic compounds , especially of architecturally complex natural products , are not easily identified . here
, we present a method to establish a strategy for such syntheses , which begins with a process termed network analysis. this exercise , along with other consi... |
a series of experiments is described in which operant methodology is used to study the effects of drugs on " learning . "
emphasis is placed on the technique of repeated acquisition as a behavioral baseline for studying this type of transition state . in this technique
, each subject is required to learn a new disc... | |
there is a strong inverse relationship between plasma high density lipoprotein ( hdl ) level and the risk of developing coronary artery disease ( cad ) .
the major role of hdl is the reverse cholesterol transport , which leads to cholesterol movement from peripheral tissue and vessel wall to the liver .
anti - infl... | background : high density lipoprotein ( hdl ) particles are heterogeneous in composition , structure , size , and may differ in conferring protection against cardiovascular disease .
hdl associated enzyme , paraoxonase-1 ( pon1 ) , has an important role in attenuation of atherogenic low density lipoprotein ( ldl ) ox... |
tissue perfusion measurement from iodinated contrast agent enhancement on ct scans was first proposed by axel in 1980 ; this was based on earlier developments by meier and zierler for measuring blood flow and blood volume . at that time , the ct - based measurements were strictly limited to research because of the lo... | deconvolution - based analysis of ct and mr brain perfusion data is
widely used in clinical practice and it is still a topic of ongoing research activities . in this paper , we present a comprehensive derivation and explanation of the underlying physiological model for intravascular tracer systems .
we also discuss... |
fake drugs and active pharmaceutical ingredients most often originate in evolving industrial economies especially developing countries before entering the global market . trafficking in counterfeit drugs
has become one of the fastest growing immoral businesses . improved technological capabilities have enabled coun... | background : fake drugs and active pharmaceutical ingredients most often originate in emerging industrial economies before entering the global market .
health care workers play a crucial role in detecting and preventing the distribution of counterfeit medicines.aim:the present study was conducted to assess the knowle... |
oral squamous cell carcinoma ( oscc ) accounts for more than 90% of all oral cancers and is the sixth most common type of cancer in the world .
the 5-year survival rate of oscc has not improved much over the past 2 decades . in china
, evidence has shown that the risk of morbidity for oscc patients is still high an... | backgroundmicrornas ( mirnas ) are small , non - coding rnas that may function as oncogenes or tumor suppressors .
previous studies have shown that the expression level of mir-1246 was enhanced in multiple types of cancers .
however , the expression of mir-1246 in human oral squamous cell carcinoma ( oscc ) and its... |
to report the case of a patient with a damaged haptic of an acrylic intraocular lens ( iol ) after transscleral iol fixation .
he had undergone phacoemulsification / aspiration and iol implantation 3 years previously and iol repositioning with transscleral fixation 2 years before the initial visit .
his visual a... | purposeto report the case of a patient with a damaged haptic of an acrylic intraocular lens ( iol ) after transscleral iol fixation.methodsthis is a retrospective and descriptive case report.resultsa 40-year - old man presented with sudden visual loss in the left eye .
he had undergone phacoemulsification / aspiratio... |
ocular trauma has been a common reason of visual morbidity , which causes heavy psychological and economic burden to victims and society [ 13 ] . in the united states , there are approximately 2.5 million cases of eye trauma every year .
ocular trauma includes mechanical eye injury ( open globe injury and closed glob... | purpose . to investigate the prognostic factors for visual outcome in traumatic cataract patients
. methods . the demographic features of traumatic cataract patients in central china were studied .
the factors that might influence the visual outcome were analyzed .
the sensitivity and specificity of ots ( ocular ... |
epstein barr virus ( ebv ) is a gamma - herpesvirus with a 172-kb dna genome , which infects more than 90% of world population .
ebv is a successful virus that utilizes normal b cell biology to infect , persist , and replicate in b cells ( thorley - lawson , 2001 ; thorley - lawson and gross , 2004 ) .
ebv predomi... | host immune system is designed ( or evolved ) to fight against different pathogens .
many viruses infect the immune cells for the propagation of new progenies , thus the infection may modulate the host immune homeostasis .
it has been more than 45 years since the discovery of epstein barr virus ( ebv ) from a burk... |
non - diabetic kidney disease in patients with diabetes is identified in biopsy - based studies with frequencies ranging 1060% [ 13 ] .
indications for kidney biopsy in patients with diabetes are the presence of features atypical for diabetic nephropathy ( dn ) ; glomerular haematuria , acute kidney deterioration or ... | in diabetic patients with acute kidney injury ( aki ) , kidney biopsy often reveals non - diabetic kidney pathology .
this case describes a patient with known type 1 diabetes who presented with aki , nephrotic syndrome and haematuria .
combination pathology of seronegative anti - glomerular basement membrane antibo... |
dna fragments were cleaned - up , end - repaired , a - tailed , and ligated with methylated paired - end adapters ( purchased from atdbio ) .
see supplementary information for details . in house generated wgbs libraries were aligned using maq in bisulfite mode to the hg19/grch37 reference assembly .
subsequently , ... | dna methylation is a defining feature of mammalian cellular identity and essential for normal development1,2 .
most cell types , except germ cells and pre - implantation embryos35 , display relatively stable dna methylation patterns with 7080% of all cpgs being methylated6 . despite recent advances we still have a to... |
a thorough medline - based search was performed with mesh words , such as nephrogenic systemic fibrosis / nephrogenic fibrosing dermopathy , gadolinium , renal failure .
a relationship between exposure to gadolinium - based contrast agents and nsf was suggested in 2006 .
clinically , nsf mimics scleromyxedema , but... | nephrogenic systemic fibrosis ( nsf ) is a relatively new fibrosing disorder which has caught the attention of various specialities in the past decade .
nsf is an extremely disabling and often painful condition , affecting up to 13% of the individuals with chronic kidney disease .
the administration of a gadolinium... |
the neural adaptations to training that contribute to performance improvements depend on the type and duration of training .
for example , learning to juggle daily for six weeks leads to structural changes in white matter density that persist for four weeks following cessation of training .
shorter periods of train... | repetitive performance of a task can result in learning .
the neural mechanisms underpinning such use - dependent plasticity are influenced by several neuromodulators .
variations in neuromodulator levels may contribute to the variability in performance outcomes following training .
circulating levels of the neur... |
cachexia is a wasting syndrome for which descriptions may be found as far as 2000 years ago , and is a consequence of cancer and other diseases , such as chronic obstructive lung disease , multiple sclerosis , congestive heart failure , tuberculosis , and aids , among others , with a high impact on quality of life . in... | cancer cachexia is a paraneoplastic syndrome compromising quality of life and survival , mainly characterized by involuntary weight loss , fatigue , and systemic inflammation .
the syndrome is described as a result of tumor - host interactions characterized by an inflammatory response by the host to the presence of t... |
-aminobutyric acid ( gaba ) is the major inhibitory neurotransmitter in the central nervous system ( cns ) , playing a key role in the balance between inhibitory and excitatory circuits [ 1 , 2 ] .
therefore , it is not surprising that dysfunctions in the gabaergic system lead to pathological conditions including hyp... | numerous neurological disorders are caused by a dysfunction of the gabaergic system that impairs or either stimulates its inhibitory action over its neuronal targets .
pharmacological drugs have generally been proved very effective in restoring its normal function , but their lack of any sort of spatial or cell type ... |
depression is a common mental health problem in older adults , not only affecting mood but also leading to functional decline in those affected .
it reduces quality of life and well - being , and increases the risk of disability , suicide , and mortality .
moreover , it has a significant impact on families and heal... | backgroundphysical activity is generally considered to be effective in reducing the prevalence of depression and promoting remission of its symptoms .
however , large - scale epidemiological research on this issue is lacking in older chinese adults .
we performed a nationwide epidemiological survey to determine the... |
the mutans streptococci group ( msg ) belong to the viridans group streptococci ( vgs ) and form an important part of the normal oral flora [ 1 , 2 ] .
although the vgs are generally nonpathogenic , they have attracted attention due to their ability to act as reservoirs for antibiotic resistance genes and to transfer... | the selection of antibiotic resistance by cotrimoxazole prophylaxis was evaluated , and we characterized the mechanism of cotrimoxazole resistance in streptococcus mutans and streptococcus sobrinus . in vitro susceptibility to six antibiotics was evaluated on 64 mutans streptococci group ( msg ) isolates from a cotrimo... |
intestinal motor alterations are associated with clinical symptoms such as diarrhea , constipation , and abdominal pain .
studies demonstrated that visceral hypersensitivity and persistently altered intestinal muscle dysfunction existed in mice infected with trichinella spiralis [ 1 , 2 ] .
in fact , the adaptive r... | trichinella spiralis infection in rodents is a well - known model of intestinal inflammation associated with hypermotility .
our aim was to elucidate if th17 cells were involved in the development of gastrointestinal hypermotility in this experimental model .
intestinal inflammation was observed by hematoxylin - eo... |
a mylab 30 gold ( esaote , genova , italy ) and a linear probe ( la435 : 6 - 18 mhz , esaote , genova , italy ) were used as the ultrasonographic equipment . performed in the intensive care unit ( icu ) , a blanket was placed under the calf of the patient in order to maintain dorsosacral position .
a pad was placed b... | central venous catheterization ( cvc ) can be difficult , especially with pediatric patients in critical care .
accessing the subclavian vein ( scv ) can cause serious complications , including pneumothorax , arterial puncture , and hemothorax .
recently , the ultrasonographic ( usg ) technique has gained popularit... |
worldwide , the estimated number of persons living with the human immunodeficiency virus ( hiv ) in 2007 was 33.2 million.1 sub - saharan africa remains the most affected by the global acquired immunodeficiency syndrome ( aids ) pandemic ; more than two - thirds ( 68% ) of all people living with hiv are in this region ... | background : highly active antiretroviral therapy ( haart ) has become more accessible to human immunodeficiency virus infection / acquired immunodeficiency syndrome ( hiv / aids ) patients worldwide . there is growing concern that the metabolic complications associated with hiv and haart may increase cardiovascular ri... |
in the last few years , numerous new dental restorative materials have been introduced in
response to an increasing demand for esthetic and biocompatible materials .
the high - strength all - ceramic materials that are currently used in dentistry consist of
alumina , zirconia , pressed , castable or machinable gl... | advances in all - ceramic systems have established predictable means of providing
metal - free aesthetic and biocompatible materials .
these materials must have
sufficient strength to be a practical treatment alternative for the fabrication of
crowns and fixed partial dentures.objectivesthe aim of this study wa... |
hepatocellular cancer is the fifth most common cancer worldwide and is the fifth leading cause of cancer death in males in the usa .
although cancer incidence in the usa is generally decreasing , hcc is one of a few cancers that is increasing in incidence and death rate [ 1 , 2 ] .
the best treatment for long - ter... | objective
. the incidence / death rate of hepatocellular cancer ( hcc ) is increasing in america , and it is unclear if access to care contributes to this increase . design / patients .
575 hcc cases were reviewed for demographics , education , and tumor size .
main outcome measures .
endpoints to determine acc... |
in the last two decades , magnetic resonance imaging ( mri ) has become an indispensable tool used to diagnose , treat and monitor gynecological cancers [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ] .
the increasing access to mri in radiation oncology departments , and its superior soft tissue c... | the importance of assessing the metal - induced artefacts in magnetic resonance imaging ( mri)-guided brachytherapy is growing along with the increasing interest of integrating mri into the treatment procedure of cervical cancer .
examples of metal objects in use include intracavitary cervical applicators and interst... |
most commonly , they present with genital ambiguity . however , the phenotype may vary from normal female to normal male appearance . here
, we are describing a case of 46 xy ovotesticular dsd who presented as primary amenorrhea .
the index case , a 21-year - old female came to gynecology opd with complaint of prim... | true hermaphrodite is one of the rare variety of disorders of sex development .
most of them are genotypically females ( 46 xx ) and present as under virilized males . features of hyperandrogenism are present in those reared as females .
the commonest histological variety of gonad found in them is ovotestis , which... |
nowadays it is obvious that the disease can be divided into two groups by its pathogenesis and clinical features : the nodular lymphocyte predominant ( nlp ) and the classic subtypes . due to the development of diagnostics and the prognosis - based risk - adopted treatment strategies ,
the exact etiology of the disea... | introduction .
hodgkin lymphoma shows a well - known geographic pattern , but temporal changes have been found recently as well .
patients and methods .
439 hodgkin lymphoma patients ' clinicopathological and treatment data were processed in calendar periods of approximately ten years .
the patients were treate... |
inflammatory bowel disease ( ibd ) comprises of two major disease entities : crohn 's disease ( cd ) and ulcerative colitis .
therefore , determination of inflammatory state is crucial for the assessment of disease activity and for the optimized therapy .
however , no simple diagnostic tool for monitoring intestina... | today , cross - sectional imaging modalities , such as computed tomography enterography ( cte ) and magnetic resonance enterography ( mre ) , are particularly suited to evaluate small bowel diseases , especially crohn 's disease ( cd ) .
it is well known that cte / mre can provide excellent assessment of disease acti... |
poststroke depression ( psd ) affects approximately a third of all stroke survivors.1 the prevalence of psd reaches a maximum at roughly 36 months , diminishes by 50% at 1 year , and may remain elevated for 2 years and beyond.2,3 as such , psd can be chronic and nonremitting .
up to 35% of patients do not respond to ... | background and purposedepression is a commonly occurring and persistent sequel of stroke affecting approximately 29% of patients .
an immunological hypothesis has been put forward , and synthesis of kynurenine from tryptophan has been proposed to link inflammatory activity with neurotoxicity and neurotransmitter dysf... |
arginine metabolism to nitric oxide ( no ) via nitric oxide synthase or to ornithine via arginase is an important biological pathway ( see fig .
no has many important functions , including regulating vascular tone and facilitating cell - mediated cytotoxicity , and ornithine is the immediate precursor of polyamines ,... | backgroundarginine metabolism in tumor cell lines can be influenced by various cytokines , including recombinant human interferon- ( rifn- ) , a cytokine that shows promising clinical activity in epithelial ovarian cancer ( eoc).methodswe examined eoc cell lines for the expression of arginase in an enzymatic assay and ... |
neurocardiogenic syncope has a peak incidence in subjects in their late teens and early twenties .
the positive rate of ttt with or without a history of syncope ranges from 23.8 to 74% [ 3 - 6 ] .
many researchers have studied treatments of neurocardiogenic syncope including salt intake , physical maneuvers , beta ... | background / aimsthis study elucidated the prognostic factors for neurocardiogenic syncope in males in their late teens and early twenties.methodstilt-table testing ( ttt ) was performed on 665 males ( age range , 17 to 27 years ) following the italian protocol .
the subjects were tilted head - up at a 70 angle on a ... |
lung burden analysis was performed on 126 autopsy cases of persons who died in new york city from 1966 through 1968 .
of the 126 cases , 107 were probably non - occupationally exposed , judging by occupational history and asbestos body content of lung .
fifty - three of the 107 cases contained short chrysotile fibe... | |
mast cells have a wide variety of functions , which not only encompass regulation of immune responses , but also autoimmunity , tolerance to graft rejection , promotion of or protection from cancer , wound healing , angiogenesis , cardiovascular diseases , diabetes mellitus , obesity , and other significant diseases . ... | background : mast cells are involved in induction of angiogenesis in the early - stages of tumor development and in modulating blood vessel growth in the later stages of tumor progression.aims and objectives : this study was carried out to evaluate the association between mast cell density ( mcd ) and microvessel densi... |
the migration of an encircling silicone band through a rectus muscle is a rare postoperative complication associated with the scleral buckling procedure .
however , both kreis et al . and tan et al . have reported cases of this rare complication . here , we describe what we believe to be the first reported case o... | the migration of an encircling silicone band through a rectus muscle is a rare postoperative complication associated with scleral buckling surgery for retinal detachment . in this present study
, we describe what we believe to be the first reported case of a patient who experienced postoperative migration of an encir... |
in the olden days , chumash saw the spirit , mind and body as inseparable entities that could not be treated separately in disease .
the first steps in healing were more spiritual , which opens the mind and body to healing .
the next steps in healing may have been directed more to the mind and body . in current soc... | this article discusses the importance of the spirit and mind in health and well - being among chumash people .
prayer was the first step in healing since prayer invites the participation of god .
initiation practices are discussed that encouraged young people to develop the maturity and spiritual strength to become... |
studies on quality of life ( qol ) of a population have substantially[112 ] focused on the elderly[1325 ] .
research in the caribbean in particular has primarily examined qol of the elderly[141626 ] and outside of that studies have also examined a population 's wellbeing[2728 ] , qol of sickle cell patients and qol o... | background : studies on quality of life ( qol ) on youths are limited and have not examined determinants of qol for this cohort.aims:the current study seeks to examine the qol of jamaican youths and to build a model that identifies factors that explain qol.materials and method : during the period june to august 2006 , ... |
over the last few decades , a significant decline in cancer - related mortality of colorectal cancer ( crc ) has been observed due to the considerable progress in the diagnosis and treatment , but crc still remains a major public health problem throughout the world .
colorectal cancer is ranked second within cancer -... | background / objective . we aimed to examine the expression of lymphoid enhancer factor 1 ( lef1 ) and notch2 in colorectal cancer ( crc ) and their association with clinicopathologic variables and crc patients ' prognosis .
methods .
immunohistochemistry , quantitative real - time polymerase chain reaction ( qrt -... |
the temporomandibular joint ( tmj ) is the most regularly used joint in the human body .
it
opens and closes about 1500 to 2000 times a day and is instrumental in several functional
movements such as chewing , breathing and pronunciation.1 because the tmj is a very regularly used joint , its bone ... | aim :
to identify the relationship between anterior disc displacement and global posture
( plantar arches , lower limbs , shoulder and pelvic girdle , vertebral spine , head and
mandibles ) .
common signs and symptoms of anterior disc displacement were also
identified .
i... |
ovarian cancer is one of the most common and deadliest gynecologic cancers . in 2010 , 21880 new cases were diagnosed , and such cancer caused nearly 13850 deaths in the united states alone .
ovarian cancer usually has poor prognosis , and most patients were diagnosed at advanced stages .
the five - year survival r... | multiple layers of suppressive components including regulatory t ( treg ) cells , suppressive antigen - presenting cells , and inhibitory cytokines form suppressive networks in the ovarian cancer microenvironment .
it has been demonstrated that as a major suppressive element , treg cells infiltrate tumor , interact w... |
chronic kidney disease ( ckd ) is defined as the presence of kidney damage , or a decreased level of kidney function , for longer than 3 months5,13 ) .
ckd is known to be associated with an increased risk of bleeding following coronary intervention and the use of anticoagulants1,12,14,21 ) .
the high risk of bleedi... | objectivewe conducted a retrospective study examining the outcomes of intracerebral hemorrhage ( ich ) in patients with chronic kidney disease ( ckd ) to identify parameters associated with prognosis.methodsfrom january 2001 to june 2008 , we treated 32 ich patients ( 21 men , 11 women ; mean age , 62 years ) with ckd ... |
alzheimer 's disease ( ad ) is the most prevalent form of dementia , which affects more than 37 million people worldwide , with an estimated cost of $ 422 billion in 2009 [ 1 , 2 ] .
moreover , the incidence of the illness and the prospect of an aging population will result in rising social and economic demands
. ... | zinc , the most abundant trace metal in the brain , has numerous functions , both in health and in disease .
zinc is released into the synaptic cleft of glutamatergic neurons alongside glutamate from where it interacts and modulates nmda and ampa receptors .
in addition , zinc has multifactorial functions in alzhei... |
taiwan and the offshore island of penghu came under the japanese rule in 1895 under the treaty of shimonoseki , when the ching government of china ceded the islands to the japanese government . in 1911 ,
however , japanese ruled taiwan until the end of the second world war in 1945 .
then , the nationalist governmen... | an overview of the epidemiological , biological , and clinical studies of taenia and taeniasis in taiwan for the past century is presented .
the phenomenal observations that led to the discovery of taenia asiatica as a new species , which differ from taenia solium and taenia saginata , are described .
parasitologic... |
ameloblastoma is one of the most common types of odontogenic tumor , however , it accounts for only 1% of all oral tumors .
it is a benign tumor whose importance lies in its potential to grow to enormous size resulting in bone deformity .
the origin of the tumor is thought to be from sources that include residual e... | the term unicystic ameloblastoma ( ua ) refers to those cystic lesions that show clinical , radiographic , or gross features of a jaw cyst , but on histologic examination show a typical ameloblastomatous epithelium lining part of the cyst cavity , with or without luminal and/or mural tumor growth .
although the histo... |
wandering spleen is a known but rare entity . it may present as an acute abdominal emergency if the vascular support to the spleen is obstructed due to torsion
we report a case of a wandering spleen in a 14-year - old girl with recurrent abdominal pain due to venous outflow obstruction resulting in developing splenor... | wandering spleen is a rare cause of acute or chronic recurrent abdominal pain with a risk of splenic torsion and infarction .
we describe a case of a 14-year - old girl with chronic recurrent abdominal pain with a palpable spleen in normal position on the initial physical examination .
laboratory findings were norm... |
arsenic is a known carcinogen , and increasing evidence also suggests a possible role of chronic arsenic exposure in the development of chronic diseases , including cardiovascular diseases .
cardiovascular diseases associated with high levels of arsenic in the drinking water include atherosclerosis , hypertension , c... | background . there is inconclusive evidence from cross - sectional and cohort studies that arsenic
exposure is a risk factor involved in the development of hypertension . methods . a database search , using several keywords , was conducted to identify relevant studies .
separate odds ratio estimates for arsenic exp... |
recurrent pyogenic cholangitis ( rpc ) was first recognized as a distinct clinical entity in the 1930s by digby .
he recognized that intrahepatic biliary calculus occurred more frequently in hong kong chinese as compared to europeans . in the 1950s , cook proposed the subsequent term recurrent pyogenic cholangitis ... | recurrent pyogenic cholangitis ( rpc ) is characterized by repeated infections of the biliary system with the formation of stones and strictures .
the management aims are to treat acute cholangitis , clear the biliary ductal debris and calculi , and eliminate predisposing factors of bile stasis .
operative options ... |
hemorrhoids as one of the most common chronic anorectal diseases severely affect patients quality of life.13 hemorrhoidectomy is utilized to treat severe hemorrhoids ( especially for iii or iv degree hemorrhoids ) or hemorrhoids failing to respond to conservative therapies.4 however , hemorrhoidectomy is always associa... | objectivethe aim of this study was to investigate the effect of xiaozhi decoction ( xzd ) on posthemorrhoidectomy pain and analgesic medication consumption.methodsfrom may 2013 to march 2015 , 315 patients who underwent open hemorrhoidectomy in our hospital were enrolled in this study , of whom , 160 patients were rand... |
human societies form a dynamic and complex system , which requires frequent interaction between individuals . according to the social brain hypothesis
( dunbar , 1998 ; adolphs , 2003 ) parts of the human neo - cortex have evolved to improve survival in dynamic groups and therefore to process social information .
... | the objective of this short review is to highlight rewarding aspects of social interactions for humans and discuss their neural basis .
thereby we report recent research findings to illustrate how social stimuli in general are processed in the reward system and highlight the role of theory of mind as one mediating pr... |
perceptual systems adjust rapidly to changes in the environment , with neural and behavioral responses dynamically changing to mirror changes in the input ( sharpee et al . , 2006 ; gutinsky and dragoi , 2008 ) .
such adaptive codes provide efficient representations because they direct computational resources toward ... | perceptual aftereffects have been referred to as the psychologist s microelectrode because they can expose dimensions of representation through the residual effect of a context stimulus upon perception of a subsequent target .
the present study uses such context - dependence to examine the dimensions of representat... |
dental implants have been proven to be a reliable long - term therapy against edentulism [ 13 ] .
however , the reported high success figures of implant therapy have been based on implants inserted using two - stage surgical protocol and conventional loading . the increased demand on implant performance and the broad... | the aim of this study was to evaluate the early bone response around laminin-1-coated titanium implants .
forty - five rats distributed in three equally sized groups were provided with one control ( turned ) and one test ( laminin-1-coated ) implant and were sacrificed after 3 , 7 , and 21 days .
real - time revers... |
production of blue colored ceramic in glaze industry is of important concern for structuring of floors and walls .
this is because cobalt has mobile 3d electrons in its atomic structure ( 1 ) .
the main component , such as silica , present in ceramic are similar to glass , causing both favorite melting point and co... | background : cobalt is one of the most important constituent present in ceramic industries .
glazers are the relevant workers when they are producing blue colored ceramic , causing occupational exposure to such metal . through this study , urinary cobalt was determined in glazers in a ceramic industry when they were ... |
the nuclear spins of xenon and other noble
gases can be hyperpolarized
( hp ) to order unity by the process of spin - exchange optical pumping
( seop ) . in this two - step process
, the electron spins
of an alkali metal vapor such as rubidium are first polarized by the
absorption of angular momentum from c... | we present a systematic , multiparameter
study of rb/129xe spin - exchange optical pumping ( seop )
in the regimes of high xenon
pressure and photon flux using a 3d - printed , clinical - scale stopped - flow
hyperpolarizer . in situ nmr detection
was used to study the dynamics
of 129xe polarization as a fu... |
rat 42 and mouse ( 1)21 ion channels were expressed in xenopus laevis oocytes . for 42 receptors , subunit stoichiometry was controlled by varying the 4:2 subunit ratio and verified by voltage jump experiments .
dose - response measurements for these channels were performed with a holding potential of 60 mv .
unnat... | nicotine addiction begins with high - affinity binding of nicotine to acetylcholine ( ach ) receptors in the brain .
the end result is over 4,000,000 smoking - related deaths annually worldwide and the largest source of preventable mortality in developed countries .
stress reduction , pleasure , improved cognition ... |
localized amyloidosis , also referred to as amyloidoma , is a rare type of amyloidosis in which the amyloid deposition is focal . in soft tissues , various localizations including the breasts , the respiratory and gastrointestinal tract , and the central nervous system
have been reported.1
2
3
4
5
6
7
8... | study design case report .
objectives with only two previously reported cases , localized amyloidosis of the sacrum is extremely rare . here
we report a 64-year - old woman with a large osteolytic lesion accompanied by weakness and paresthesia of the right leg and difficulties in bladder control .
methods fine... |
polycythemia is clinically defined as elevated red blood cell mass ( hemoglobin > 18.5 g / dl in men , 16.5 g / dl in women or other evidence of increased red cell volume or hemoglobin or hematocrit greater than 99th percentile of method - specific reference range for age , sex , altitude of residence or hemoglobin gre... | two polycythemic subjects from a family with multiple polycythemic subjects were evaluated .
estimation of oxygen affinity of hb from venous blood gas parameters ( p50 ) revealed low p50 suggesting a high affinity hb variant .
further work up , which included beta globin gene sequencing , revealed a novel mutation ... |
sex cord - stromal tumors of ovary account for approximately 5 - 8% of all ovarian tumors ( 15 ) .
they are composed of granulosa cells , theca cells , sertoli cells , leydig cells and fibroblasts singly or in various combinations ( 2 , 6 ) .
leydig stromal tumor is a rare member of this group that accounts for les... | leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex - cord stromal tumors .
they produce testosterone leading to hyperandrogenism .
we present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra sonography , and a rise of total and free serum testostero... |
proteins
are essential components of all organisms , carrying out
tasks defined by the information encoded within genes , for example
catalyzing biochemical reactions , mediating cell signaling , or providing
structural rigidity .
simulations range from elucidation of enzymatic
reaction mechanisms , to the ... | atomic partial charges for use in
traditional force fields for
biomolecular simulation are often fit to the electrostatic potentials
of small molecules and , hence , neglect large - scale electronic polarization .
on the other hand , recent advances in atoms - in -
molecule charge derivation
schemes show pr... |
operating room ( ors ) fires related to anaesthesia ventilator mishaps are extremely rare events , but when they do occur , result in serious and sometimes mortal consequences .
cardiac arrest associated with ventilator fire has not been reported in the published english literature .
we report a near - fatal incide... | operating room fires are rare events , but when occur they result in serious and sometimes fatal consequences .
anaesthesia ventilator fire leading to cardiac arrest is a rare incident and has not been reported .
we report a near catastrophic ventilator fire leading to cardiac arrest in a patient undergoing subtota... |
moreover , there are no blood markers for the early detection of lung cancer ( unlike for cancers such as prostate , colorectal , and gynecological cancers ) ( 1 ) . in the past , non - specific cytotoxic agents were the first choice of treatment for patients with stage iv non - small - cell lung cancer ( nsclc ; eithe... | lung cancer remains the leading cause of death due to cancer .
we do not have effective tools for the early detection of lung cancer , so patients are usually diagnosed at an advanced stage .
however , novel therapies based on molecular pathways ( such as those involving the epidermal growth factor receptor , anapl... |
a 32-year - old , 173 cm , 79 kg male patient was admitted to the emergency room ( er ) for the treatment of facial pain due to an automobile accident . on arrival , he was fully conscious with an glasgow coma scale score of 15/15 and stable vital signs : blood pressure ( bp ) 115/76 mmhg , heart rate ( hr ) 58 beats /... | long qt syndrome ( lqts ) is an arrhythmogenic cardiovascular disorder resulting from mutations in cardiac ion channels .
lqts is characterized by prolonged ventricular repolarization and frequently manifests itself as qt interval prolongation on the electrocardiogram ( ecg ) .
a variety of commonly prescribed anes... |
a metal block of dimension 3 mm 3 mm 3 mm was fabricated using auto - cad wire cut iridium technology ( electronic , electra , mektron , maxicut 734 ) for standardizing the dimensions of the zirconia blocks .
the metal block was scanned using a software for cad / cam machine ( intelli denta , dental smart products ... | statement of problem : although ceramic veneered on to zirconia core have been in use for quite some time , information regarding the comparative evaluation of the shear bond strength of pressable & layered ceramic veneered on to zirconia core is limited.purpose of study : to evaluate the shear bond strength of zirconi... |
tall cell variant papillary thyroid carcinoma ( tcv ) was first described in 1976 by hawk and hazard as an aggressive histological variant of papillary thyroid cancer .
tcv is defined as tall papillary epithelial cells with a height at least twice the width and basement membrane oriented nuclei comprising at least 30... | objective . to evaluate the prognosis of tall cell variant ( tcv ) compared to usual variant ( uv ) papillary thyroid cancer by comparing disease - related mortality and recurrence data from published studies
. methods .
ovid medline keyword search using tall cell variant papillary thyroid cancer was used to iden... |
during october 12 , 2014march 28 , 2015 , samples collected from 1,058 persons in liberia with suspected ebov infection were submitted to the cdc nih elwa laboratory .
the samples used for this research were collected for public health surveillance and not human subjects research , so institutional review board revi... | malaria is a major public health concern in the countries affected by the ebola virus disease epidemic in west africa .
we determined the feasibility of using molecular malaria diagnostics during an ebola virus disease outbreak and report the incidence of plasmodium spp .
parasitemia in persons with suspected ebola... |
managing financial resources is one of the main functions of a healthcare system ( 1 ) .
different methods are used to collect revenue in healthcare systems , such as public taxes , compulsory contributions for social health insurance ( usually based on one s wages with little or no consideration of risks ) , volunta... | background : direct out - of - pocket ( oop ) payment is the most inequitable way to pay for healthcare services , and this trend exposes patients and their families to backbreaking financial risks .
the aim of this study was to estimate the out - of - pocket expenditures for outpatient imaging services in imam - kho... |
the synthesis and maturation of rnas are tightly controlled , and they shape complex gene expression networks that ultimately drive biological processes . these networks need to be robust as well as highly plastic in order to allow rapid adaptation to environmental or genetic perturbations .
an in - depth understandi... | next - generation sequencing technologies are now being exploited not only to analyse static genomes , but also dynamic transcriptomes in an approach termed rna - seq .
although these powerful and rapidly evolving technologies have only been available for a couple of years , they are already making substantial contri... |
the prevalence of overweight and obesity is high in most parts of the world , and this is particularly alarming not only for the increasing risk of multiple comorbidities , but also due to the tendency of childhood overweight and obesity to track into adulthood . the metabolic syndrome ( mets ) , a cluster of sever... | introduction . this study aimed to evaluate the screening performance of different measures of adiposity : body mass index ( bmi ) , waist circumference ( wc ) , and waist - to - height ratio ( whtr ) for high metabolic risk in a sample of adolescents . methods .
a cross - sectional school - based study was conducted... |
heat transfer is the transition of thermal energy or simply heat from a hotter object to a cooler object .
when an object is at a different temperature than its surroundings or another object , heat transfer occurs in such a way that the body and the surroundings reach thermal equilibrium .
heat transfer always occ... | the scale effect of heat conduction of air in nano spacing ( ns ) is very important for nanodevices to improve their life and efficiency . by constructing a special technique ,
the changes of heat conduction of air were studied by means of measuring the heat conduction with heat conduction instrument in ns between th... |
nerve terminals are generally considered the destination points for electrical signals , which propagate unidirectionally from the soma to nerve terminals . here
, we demonstrate that small hyperpolarizations or depolarizations ( ~10 mv ) , generated under physiological conditions in rat nerve terminals , backpropaga... | |
microbial keratitis ( mk ) , epithelial loss from the cornea with underlying stromal infiltration by white blood cells and disintegration of the stroma , occurs when one of the protective mechanisms of the ocular surface is disrupted .
it is a vision - threatening condition that requires rapid and appropriate managem... | pubmed and medline were searched for articles referring to pseudomonas keratitis between the years 2007 and 2012 to obtain an overview of the current state of this disease .
keyword searches used the terms pseudomonas
+ keratitis limit to 20072012 , and [ ulcerative or microbial ] + keratitis
+ contact... |
obesity is associated with increased morbidity and mortality from cardiovascular disease , type 2 diabetes , and fatty liver disease , all of which have been clearly linked to a chronic , low - grade inflammatory status .
multiorgan involvement of obesity - induced inflammation ( liver and adipose tissue ) , sex diff... | objective . obesity is associated with metabolic dysfunction with sex differences and chronic , low - grade inflammation .
we proposed that hepatic expression of immune complement c3 related receptors ( c3ar , c5ar , and c5l2 ) would be associated with pre- or postmenopausal status and metabolic profile in severely o... |
peripheral neuropathy is a common , but a debilitating adverse effect of several classes of chemotherapeutic agents including vinca alkaloids , taxanes , and antitubulins .
the incidence of chemotherapy - induced peripheral neuropathy ( cipn ) can vary from 3% to 7% with a single agent and rise up to 38% in patients ... | chemotherapeutic agents belonging to vinca alkaloids , taxanes , and antitubulins produce peripheral neuropathy for which there is no validated treatment .
pregabalin , a gamma - aminobutyric acid analog , is known to inhibit the2 subunit of the voltage - gated calcium channel .
earlier studies and case reports hav... |
despite enormous efforts to search for cure , diabetes mellitus ( often simply referred to as diabetes ) still remains as a formidable challenge for public health . as of 2000
at least 171 million people worldwide suffer from diabetes or 2.8% of the population , and the prevalence of diabetes will rise to 11.4% in 20... | panax ginseng exhibits pleiotropic beneficial effects on cardiovascular system , central nervous system , and immune system . in the last decade , numerous preclinical findings suggest ginseng as a promising therapeutic agent for diabetes prevention and treatment .
the mechanism of ginseng and its active components i... |
hearing aid validation using aided speech evoked auditory evoked potentials is of research and clinical interest .
such measurements involve elicitation of an evoked potential using a speech stimulus that has been processed through a hearing aid .
hearing aids , being mostly nonlinear , may have implications for th... | background .
functioning of nonlinear hearing aids varies with characteristics of input stimuli . in the past decade , aided speech evoked cortical auditory evoked potentials ( caeps ) have been proposed for validation of hearing aid fittings . however , unlike in running speech , phonemes presented as stimuli during... |
hepatitis c virus ( hcv ) is a ribonucleic acid ( rna ) virus that causes chronic hepatitis and liver failure , worldwide.1,2 it consists of six different genotypes that are differentially distributed geographically.3,4 success of treatment varies greatly depending on the genotype.4,5 the genome contains cis - acting r... | background and aimsthe noncoding regions in the 3-untranslated region ( utr ) of the hepatitis c virus ( hcv ) genome contain secondary structures that are important for replication .
the aim of this study was to identify detailed conformational elements of the x - region involved in hcv replication.methodsribonuclei... |
a 63-year - old male presented with complaints of gradually progressive painless diminution of vision in the left eye since last 1 year .
the patient had undergone left eye optical penetrating keratoplasty 10 years back for leucomatous corneal opacity post corneal ulcer , managed medically .
the patient presented t... | we report a 63-year - old male who had undergone left eye optical penetrating keratoplasty for central leucomatous corneal opacity 10 years earlier .
the eye had clear donor graft with residual astigmatism of 6.50 diopter cylinder ( dc ) at 30. the patient underwent clear corneal phacoemulsification with implantation... |
clathrin - independent endocytosis includes the constitutive pinocytotic pathway as well as endocytosis mediated by caveolae and glycolipid rafts .
glycolipid rafts are detergent - insoluble , low - density membrane fractions that are rich in cholesterol and sphingolipids ; caveolae are cholesterol- and sphingolipid ... | although caveolae are well - characterized subdomains of glycolipid rafts , their distinctive morphology and association with caveolins has led to their internalization being considered different from that of rafts . in this review
, we propose that caveolae and rafts are internalized via a common pathway , caveolae ... |
organisms ' adaptation to environmental stress has become a subject of great interest over the last decades [ 15 ] . like other organisms
, budding yeast saccharomyces cerevisiae has developed several strategies to survive stressful changes in their environment .
clearly , yeast cells respond rapidly and modify the... | the biphasic - dose response of microorganisms to hydrogen peroxide is a phenomenon of particular interest in hormesis research . in different animal models ,
the dose - response curve for ethanol is also nonlinear showing an inhibitory effect at high doses but a stimulatory effect at low doses . in this study
, we... |
lateral closed wedge high tibial osteotomy ( hto ) described by jackson and waugh and coventry is an established technique to treat osteoarthritis of the medial compartment and varus deformity .
the advantages of a medial opening wedge osteotomy compared with a lateral closing wedge osteotomy include easier te... | purposethe aim of this study was to establish an evaluation system to monitor bone formation and beta - tricalcium phosphate ( tcp ) resorption in opening high tibial osteotomy ( hto).methodsfrom 2003 to 2005 , opening hto was performed in 36 patients using a puddu plate and -tcp blocks with 60 and 75 % porosity .
t... |
degenerative cervical spondylolisthesis ( dcs ) is a pathological condition defined by anterolisthesis or anterior slippage of the cervical spine ( c - spine ) vertebrae .
underlying causes of this slippage include application of a shear force on the vertebra , disc degeneration , and/or hypertrophic arthropathy of t... | objectiveto measure the orientation of the facet joints of cervical spine ( c - spine ) segments in the sagittal plane , known as the pedicle - facet ( p - f ) angle , and to use these measurements to evaluate the relationship between the p - f angle and the amount of vertebral anterolisthesis in patients with degenera... |
the strains that were the subject of this study and their source collections are listed in table1 .
the nutrient utilization data presented in table1 are sorted in the same order as the 16s plastid rdna tree .
the names in the authority column conform to the convention given in algaebase.org ( guiry and guiry 2014 ... | because algae have become more accepted as sources of human nutrition , phylogenetic analysis can help resolve the taxonomy of taxa that have not been well studied .
this can help establish algal evolutionary relationships . here
, we compare auxenochlorella protothecoides and 23 strains of prototheca based on thei... |
during recent years , infection of acinetobacter baumanii showed a rapid growth in hospitals and community .
baumanii infection mainly occurs in the lung and blood , the notable feature being that multi - drug resistant strains cause outbreaks in hospitals .
large outbreaks of a. baumanii infection have been report... | background : during recent years , infection of acinetobacter baumanii showed a rapid growth in hospitals and community .
toll - like receptors ( tlrs ) are the most important pattern recognition receptors , which play a critical role during recognizing invading pathogens by the natural immune system .
our objectiv... |
a 56-year - old male visited our hospital with new york heart association functional class iv dyspnea and pitting edema in his lower extremities .
the patient had been diagnosed with tricuspid valve regurgitation and atrial fibrillation at an outside institution 10 years ago . however , the patient had refused surgic... | a 56-year - old male presented with severe exertional dyspnea and pitting edema in the lower extremities .
the pre - operative evaluation demonstrated biventricular dysfunction associated with severe tricuspid valve regurgitation and a persistent left superior vena cava .
he was registered as a transplantation cand... |
ninety - percent of head and neck cancers are squamous cell carcinomas ( scchn ) involving the mucosal surfaces of the oral cavity , pharynx , and larynx .
the overall relative 5-year survival rates for cancers of the oral cavity / pharynx and larynx are estimated to be 58.3% and 64.5% , respectively .
morbidities ... | the epidermal growth factor receptor- ( egfr- ) directed antibody , cetuximab , was fda - approved for the treatment of squamous cell carcinoma of the head and neck ( scchn ) in 2006 .
additional egfr - targeting agents in clinical development for scchn include other egfr - directed antibodies , tyrosine kinase inhib... |
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