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135
6beb2aef-93d4-4f71-b0a3-999d8c51ace5
Following is true about safety muscle of tongue
Innervated by cranial pa of accessory nerve
Hypoglossal nerve
Attached to hard palate
None of the given options
1b
multi
Ref BDC volume 3,6th edition pg 268Genioglossus is a life-saving muscle and its action is to protrude the tongueAll intrinsic and extrinsic muscles except palatoglossus are supplied by hypoglossal nerve
Anatomy
Head and neck
0571ed99-b1fd-4109-a842-216efc3864ac
Large PDA leads to ?
Endocardial valvulitis
Eisenmenger syndrome
CHF
All of above
3d
multi
Ans. is 'd' i.e., All of above Patent ductus aeriosus (PDA) Small PDA may not cause any complication but large defect if untread may leads to : Pulmonary hypeension Left to Right shunt leads to too much circulation of blood in lung which leads to pulmonary hypeension. Eisenmenger's syndrome - Large standing pulmonary h...
Pediatrics
null
3979dbb1-3a9d-4b52-ab3c-aee2e0d9768b
Pure-tone audiometry of a 30 year old field worker shows Carha's notch. He has the following condition:
Otospongiosis
CSOM
Meniere's disease
Acoustic neuroma
0a
single
The hallmark of bone conduction thresholds in otosclerosis/otospongiosis is the Carha notch. This is characterized by the elevation of bone conduction thresholds of approximately 5, 10, and 15 dB at 500, 1000, and 2000 Hz, respectively. The Carha notch is thought to result from the disruption of normal ossicular resona...
ENT
null
4fe082aa-a379-4e3d-a4d0-40966c942b94
Cells of kidney having secretory function
I cell
P cell
JG cell
All
2c
multi
C. i.e. JG cells
Anatomy
null
d78edcd1-a48e-458c-99cb-e6388146efdf
The drug which releases NO
Hydralazine
Aminophylline
Amrinone
Sildenaphil
0a
multi
Ans.is'a'i.e.,HydralazineRef:GoodmanGilmanlTthlep'863, 249, 825NO donors, which release NO are used to elicit smooth muscle relaxation.Eg: Organic nitrates (nitroglycerine), Organic nitrites (Isoamylnitrite), Sodium nitroprusside, Nebivolol & Hydralazine
Pharmacology
null
7c4b0938-8096-4f42-852e-7885e1f19517
Respiratory acidosis is characterized by primary:
Deficit of carbonic acid
Excess of carbonic acid
Deficit of bicarbonate
Excess of bicarbonate
1b
single
Respiratory acidosis is caused by CO2 retention - excess carbonic acid.
Pediatrics
Body composition and Acid base Balance
39e1d8ed-c363-4a3c-9dd6-cfd5916a24a0
Most common manifestation of congenital toxoplasmosis
Hydrocephalus
Chorioretinitis
Calcification
Convulsions
1b
single
Most common - Chorioretinitis In adults - Cervical lymphadenopathy.
Microbiology
null
d86d51d5-8847-4278-8f17-b64f03f22fbb
Most afferent fibers from the lateral geniculate nucleus terminate in the primary visual coex is:
Layer 1
Layer 2 & 3
Layer 4
Layer 5 & 6
2c
single
C i.e. Layer 4Afferents from Lateral geniculate body terminate onto the visual coex, mostly through the magnocellular, and parvocellular pathways. Axons from parvocellular and magnocellular pathway, both terminate in Layer 4 of the visual coex.The axons from Lateral geniculate nucleus that form the magnocellular pathwa...
Physiology
null
b39fdea1-3a3e-4331-b8f4-de9d68662b5c
The most common presentation of endemic goitre
Diffuse goitre
Solitary nodule
Hypothyroid
Hypehyroid
0a
single
Endemic Goiter Worldwide, diffuse goiter is most commonly caused by iodine deficiency and is termed endemic goiter when it affects >5% of the population Endemic goiter occurs in geographical areas where soil, water and food supply contains low levels of iodine The lack of iodine leads to decreased Synthesis of thyroid ...
Surgery
Endocrinology and breast
9d76d36e-fb8b-498f-a7ed-3501ed8a35a5
MTP Act was introduced in:
1961
1971
1981
1991
1b
single
Ans: B (1971) Ref: The Essentials of Forensic Medicine and Toxicology by KS Narayan Reddy. 29th edition. 2010.Explanation:The Medical Termination of Pregnancy (MTP) Act of IndiaIt clearly states the conditions under wfhich a pregnancy can be ended or aborted, the persons who are qualified to conduct the abortion and th...
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
b25df54c-b496-455e-906d-e40e3e508eb6
Infective endocarditis after tooth extraction is probably due to ?
Streptococcus viridans
Streptococcus pneumoniae
Streptococcus pyogenes
Staphylococcus aureus
0a
single
Ans. is 'a' i.e., Streptococcus viridans Viridans streptococci are normally resident in the mouth and upper respiratory tract. They cause transient bacteremia following tooth extraction or other dental procedures; and get implanted on damaged or prosthetic valves or in a congenitally diseased hea, and grow to form vege...
Microbiology
null
3b73952f-6619-4726-9925-c7d96f94144d
Sternum attached to scapula
Manubrium
Clavicle
First rib
Second rib
1b
single
Sternum or chest bone is attached to scapula which is present on posterior surface with help of clavicle or collar bone so that weight of upper limb is transmitted to axial skeleton scapula,Clavicle and sternum
Anatomy
Osteology
a75fe2a4-c4a8-4fc3-a989-4fef0ab97005
Adenoma sebaceum is seen in
Scleroderma
Tuberous sclerosis
SLE
Systemic sclerosis
1b
single
i.e. (Tuberous sclerosis): (96Q-CMDT-11) (1798 -1000-H17th)* Adenoma sebaceum subungual fibromas, shagreen patches (leathery plaques of subepidermal fibrosis) and leaf shaped hypopigmented spots - cutaneous abnormalities seen in TUBEROUS - SCLEROSIS* Renal abnormalities includes - Renal cysts, Angiolipomas, Renal cell ...
Medicine
Skin
1d9e3cf3-13d2-455a-b4be-0ecd106deed2
In vitro DNA amplification is done by
Blotting technique
Recombinant technique
Electrophoresis
Polymerase chain reaction
3d
single
(D) Polymerase chain reaction # DNA amplification is done by PCR> Blotting technique Following gel electrophoresis, probes are often used to detect specific molecules from the mixture. However, probes cannot be applied directly to the gel. The problem can be solved by three types of blotting methods: Southern blotting,...
Medicine
C.N.S.
411889a1-cd2b-44cd-99a1-ce8714ba8707
Triad of Reiter's syndrome includes all except
Conjunctivitis
Ahritis
Urethritis
Uveitis
3d
multi
Conjunctivitis in eye
Anatomy
All India exam
ab5d86b9-b0f5-4e43-954f-8d0790ede7b1
Anaesthetic agent that predisposes to maximum arrhythmias –
Isoflurance
Enflurane
Halothane
Ether
2c
single
Amongst the inhalational agents, Halothane has the maximum propensity to sensitize heart to adrenaline → Arrhythmia can occur.
Anaesthesia
null
10d29a63-ec02-4169-85e5-3d08f296c65b
Pathological changes of diabetic nephropathy are all except:
Fibrin caps and capsular drops
Kimmelstein-Wilson lesion
Basement membrane thickening
Focal glomerular sclerosis
3d
multi
Diabetes may cause nodular and diffuse glomerulosclerosis but not focal glomerular sclerosis. Diabetes Mellitus - |ed glucose - non enzymatic glycosylation - Advanced glycation end products - efferent aeriole - |ed filtration injury - Nodular glomerulosclerosis ( most characteristic) : Kimmelstein Wilson lesion - diffu...
Pathology
Systemic Disorders affecting Glomerulus
fc2bc39e-d897-4589-b026-222c7f50395d
A 15-year-old vegetarian being treated for tuberculosis develops peripheral neuropathy. choose the one most appropriate vitamin or trace element replacement therapy to treat the described condition.
Vitamin A
Niacin (Vitamin B3)
Pyridoxine (Vitamin B6)
Folate (Vitamin B9)
2c
single
Treatment for tuberculosis usually includes the medication isoniazid (INH), and INH competitively inhibits pyridoxine utilization. In most children, this does not result in clinical manifestations, but in individuals with a poor dietary intake of pyridoxine (eg, teenagers, vegetarians, and exclusively breast-fed infant...
Pediatrics
Gastro Intestinal System
83366d28-b39a-4e7b-a3e4-04f3797d915d
A case of polytrauma with blunt abdominal injury presents to the casualty. The first investigation to evaluate his abdomen is -
USG
CT Scan
CompleteHemogram
Abdominal X-ray
0a
single
Ans. is 'a' i.e., USG o Has been explained in previous sessions
Surgery
Abdominal Injury
4d35f1b3-a62a-461c-b9f5-8054860f80e2
IMCI approach developed by WHO encompasses following childhood illnesses Except
Malaria
Measles
Diarrhoea
Chicken pox
3d
multi
The most common causes of infant and child moality in developing countries (including India) are:-Acute respiratory infections-Diarrhoea-Malaria-Measles and-Malnutrition IMCI approach developed by WHO encompasses these childhood illnesses. Ref : Park 23rd edition Pgno : 576
Social & Preventive Medicine
Health programmes in India
0398cbc5-09d6-47b8-996b-1ad44df0b979
A 70 yr old man presents with 10 prosopagnosia loss of memory, 3rd person hallucination for 1 month. On examination deep Tendon reflexes are increased, mini-mental examination score is 20/30. What is most likely diagnosis:
Dissociated Dementia
Schizophrenia
Alzheimer's disease
Psychotic disorder
2c
multi
C i.e. Alzheimer's diseaseDuration of 1 month only, is enough to rule out schizophrenia, in which duration should be at least 6 monthsIn psychiatric disorders like schizophrenia & psychosis, there may never be organic symptoms like increased tendon reflexes.Features of Alzheimer dementia areMemory impairment without im...
Psychiatry
null
f4028799-3d03-4ce0-afb6-90360cd29b98
Innovation of refrigeration leading to better food preservation has led to decrease incidence of which of the following malignancies?
Esophagus
Colon
Oropharyngeal
Stomach
3d
single
Ans is 'd' i.e. Stomach "This sharp decline (in gastric cancer) during the 20th century remains an unexplained yet staling phenomenon. The leading theories to explain this change concern the advent of refrigeration and infection with Helicobacter pylori." Int. J. Epidemiol. (2001) 30 (1):181-182 Stomach cancer used to ...
Surgery
null
8db3d1ee-7868-4b65-8f8b-6e2bf3cff4f6
A 75 year old woman complains to a physician of facial pain, headache, and intermittent visual symptoms. Both temporal aeries are biopsied. If the biopsies show abnormal vessels, which of the following would be the most likely pathological finding?
Atherosclerotic plaque
Fibrinoid necrosis
Focal granulomatous inflammation
Fungal hyphae
2c
multi
The suspected disease is temporal aeritis, also known as giant cell aeritis, because of the focal granulomatous inflammation (with giant cells) that characterizes the process. The cranial aeries (branches of the carotid system) are most often involved. Vigorous attempts at diagnosis, which may require biopsying 2-cm le...
Skin
null
4d7c90fc-0e78-4429-834e-749cbf46ad0a
Working formulation in staging of non-hodgkins lymphoma is based on: March 2010
Morphology of cells
Cell surface markers
Survival characteristic of cells
Cellular genetics
0a
single
Ans. A: Morphology of cells The 1982 Working formulation is a classification of non-hodgkin lymphoma. It excluded the Hodgkin lymphomas and divided the remaining lymphomas into four grades (Low, Intermediate, High, and Miscellaneous) related to prognosis, with some fuher subdivisions based on the size and shape of affe...
Medicine
null
587f9a84-bd87-4742-88cc-48ff7779af66
Kwashiorkor is characterised by all of the following features except –
Edema.
Patchy depigmentation of hair
Fatty liver
Fatty infiltration of pancreas
3d
multi
Kwashiorkor and marasmus are manifestations of protein-energy malnutrition (PEM). Marasmus represents the compensated phase of PEM. Kwashiorkor represents the uncompensated phase of PEM. Kwashiorkor It is characterized by following three essential features - 1) Edema Edema starts in lower extremities and later invo...
Pediatrics
null
3c9b240d-267f-430d-8724-069ac9626418
Traveller's diarrhoea is most commonly caused by
ETEC
S. dysenteriae
EPEC
Salmonella
0a
single
Ans. a (ETEC). (Ref. Harrison, 18th/Table 149-2; Chapter 149. Diseases by Gram-Negative Enteric Bacilli)Five types of E.coli include:1. ETEC (enterotoxogenic E.coli)2. EIEC (enteroinvasive E.coli)3. EPEC (enteropathogenic E.coli)4. EHEC (enterohemorrhagic E.coli)5. EAEC (enteroaggregative E.coli)Traveller's diarrhoea i...
Microbiology
Enterobecteriaceae
d8a006d7-866c-4c56-b0eb-2d844b909a6a
A 50-year-old male with a positive family history of prostate cancer has come to you for a screening test. The most sensitive screening test to pickup prostate cancer is:
DRE
PSA
DRE + PSA
Endorectal Coil MRI with T1W and T2W images
2c
single
Smith's Urology writes - "At the present time the data suggest that if screening is done, the combination of DRE & Serum PSA is best." The diagnosis of Ca Prostate is established by TRUS-guided transrectal biopsy.
Surgery
null
fb4c132c-cc8e-443e-afa5-963e33130c10
A 12-year-old boy has a cough and earache for the past 2 days. He has a history of recurrent infections, including otitis media, diarrhea, and pneumonia. Physical examination shows an erythematous right tympanic membrane, a cleft palate, and murmur suggestive of congenital heart disease. A thoracic CT scan shows a smal...
Adenosine deaminase assay in lymphocytes
Branched DNA assay for HIV-1 RNA level
FISH analysis with a probe for chromosome 22q11.2
Lymph node biopsy
2c
multi
DiGeorge syndrome is an immunodeficiency characterized by infection, a small thymus, congenital malformations, and hypoparathyroidism. This cluster is characteristic of the 22q11.2 deletion syndrome, readily diagnosed by FISH. Adenosine deaminase deficiency can cause immunodeficiency, but it is not associated with cong...
Pathology
Genetics
9dda9c57-61ae-427b-b641-d3e852b82bf9
Enzyme involved in cleavage of glycine in liver mitochondria is
Pyruvate dehydrogenase
Dihydrolipoyl transacetylase
Dihydrolipoyl
None of these
2c
multi
Starvation. All the three amino acids undergo similar sequence of reactions. These are summarized in Table 16.2. In this pathway, the second enzyme is a branched chain alpha-keto acid dehydrogenase. It is a complex of decarboxylase, transacylase and dihydrolipoyl dehydrogenase. So, this resembles pyruvate dehydrogenase...
Biochemistry
Enzymes
189663f9-fa01-48a4-9ee0-0a330988485f
If the bih weight is 3 kg by the end of one year of age. It should become:
6 Kg
9 Kg
12 Kg
15 Kg
1b
single
Average bih weight in India: 2.8 Kg (2.7-2.9 Kg) BW doubles at 5 months, triples by 1 year and quadraples by 2 years age So, BW of 3 Kg will become 6 Kg, 9 Kg and 12 Kg at 5 months, 1 year and 2 years age respectively. Weight gain Pattern in Children Age Weight increments 0-3 months 200 grams per week 4-6 months 150 gr...
Social & Preventive Medicine
Maternal and child care
557c807d-094a-46dc-9feb-ae841c2e9f7d
True regarding Keratoacanthoma:
Central ulceration is uncommon
Known as Molluscum sebaceum
Caused by pox virus
Heals without scarring
1b
multi
Central ulceration is very common Known as Molluscum sebaceum Caused by pox virus is a false statement Heals with scarring as it is a severe condition Keratoacanthome (KA) is a relatively common low grade tumor that originates in the pilosebaceious glands and closely resemble squamous cell carcinoma (SCC) Lesion shows ...
Dental
Viral infections
3ff46e92-b095-4f40-911f-06fcd31daf76
Commonest site of Ivory osteoma -
Frontal-Ethmodial region
Mandible
Maxilla
Sphenoid
0a
single
Ivory osteomas are most commonly seen in frontal sinus followed by ethmoid and maxillary sinus.
ENT
null
8949ef83-58bc-4536-9735-9a09734df12e
Congenital anomalies are most severe in:
Rubella infection
Mumps
CMV
Toxoplasma
0a
single
Ans. is a, i.e. Rubella infectionRef. Williams Obs. 23/e, p 1214"Rubella is one of the most teratogenic agents known." Ref. Williams Obs. 23/e, p 1214Rubella causes a number of serious defects in fetus. These defects may occur singly or in combination called Congenital rubella syndrome.
Gynaecology & Obstetrics
Medical & Surgical Illness Complication Pregnancy
6d71ffb5-12aa-46f1-84a3-1849029c6f93
The intermediate host for T. Saginata is:
Man
Cow
Dog
Pig
1b
single
Cow
Microbiology
null
0332f53c-1444-4264-91cc-6b0cf371b18b
All of the following are true about vasectomy, EXCEPT:
Take about 3 months before the sperm stores are used up
Sperm granulomas are less common if electrocautery is used
Reversal is most successful within 10 years of initial surgery
There is a risk of chronic testicular pain
1b
multi
Sperm granulomas are less common if thermal cautery is used rather than electrocautery. Some complications of vasectomy: a) Hematoma and infection b) Sperm Granulomas c) Chronic testicular pain d) Spontaneous recanalisation e) Antisperm antibody formation Ref: Oxford Handbook of Clinical Specialities, 8th Edition, Page...
Social & Preventive Medicine
null
5eca40b1-7194-40aa-bdbe-994aa0d9e1c4
A 3-year-old boy's parents complain that their child has difficulty walking. The child rolled, sat, and first stood at essentially normal ages and first walked at 13 months of age. Over the past several months, however, the family has noticed an increased inward curvature of the lower spine as he walks and that his gai...
Occult spina bifida
Muscular dystrophy
Brain tumor
Guillain-Barre syndrome
1b
multi
The most common form of muscular dystrophy is Duchenne muscular dystrophy. It is inherited as an X-linked recessive trait. Male infants are rarely diagnosed at birth or early infancy since they often reach gross milestones at the expected age. Soon after beginning to walk, however, the features of this disease become m...
Pediatrics
Musculo Skeletal Disorders
c3aee211-501d-4e8e-b849-b4d17e52c0e6
Most common muscle affected in rotator cuff group is -
Supraspinatus
Infraspinatus
Teres minor
Subscapularis
0a
single
Ans. is 'a' i.e., Supraspinatus * Rotator cuff is the group of muscles and their tendons around the shoulder that act to stabilize the shoulder. As it consists both muscles and tendon, it is also referred to as musculotendinous cuff of the shoulder. Muscles which forms the rotator cuff arise from the scapula and are in...
Orthopaedics
Injuries Around Shoulder
98c44bf6-d352-4c6f-8953-f79b160de4c8
Serum analysis of a patient with acute anterior wall myocardial infarction shows abnormal lipid profile. Which of the following lipoprotein is MOST closely associated with hea disease?
Chylomicrons
VLDL
LDL
HDL
2c
multi
LDL cholesterol was prospectively associated with a threefold increased risk of coronary hea disease (CHD), independent of total cholesterol, HDL, and body mass index. The NCEP III guidelines recognize small, dense LDL as a CVD risk factor. LDL delivers cholesterol to peripheral tissues, including atheromatous lesions,...
Medicine
null
13cea46f-9b13-4605-8f5d-c5a03e4d2cb2
Which of the following is true about non specific interstitial pneumonia?
Common in elderly age group
Good prognosis
Early honeycombing
Males are affected more commonly then females
1b
multi
Non specific interstitial pneumonia is usually presented at a younger age group,most commonly in women .HRCT shows bilateral,subpleural ground-glass opacities,often associated with lower lobe volume loss.Patchy areas of airspace consolidation and reticular abnormalities may be present,but honeycombing is unusual.The ma...
Medicine
Respiratory system
2e5620f5-2568-468b-87d0-a4ba8c3970ab
A 45 year old Alcoholic comes to OPD who is on abstinence since last 10 years.He suddenly develops dysahria, shuffling gait and intention tremors . What shall be the most likely diagnosis ?
Wilson disease
Wernicke's disease
Acquired hepatocerebral degeneration
Halloverden spatz disease
2c
multi
Disease Features Wilson's ds -Patient will be present at 10 yr age -KF Ring -But here it is alcoholic so ruled out. Wernicke's disease -Global confusion, -Ophthalmoplegia -Ataxia Hepatocerebral degeneration -Rare complication of cirrhosis -Indicates a decompensation in of cirrhosis - Development of Poal HTN - develops ...
Medicine
DNB 2018
47b51eac-a25a-4ee0-9864-0b2c8e48f7d4
Takayam test is used for ?
To know the nature of stain
To know the species
For blood grouping
None of the above
0a
multi
Ans. is 'a' i.e., To know the nature of stain It is a microchemical test to know the nature of stain.Microchemical tests :These tests are based on propey of haem pa of hemoglobin to form characteristic coloured crystals.Teichmann's haemin crystal testTakayama hemochromogen crystal testLuminal spray test : It is especia...
Forensic Medicine
null
35af115a-ca54-4e48-a172-db9cce930f12
Earliest congenital malformation that may be detected on USG is
Down's syndrome
Hydrocephalous
Anencephaly
Sacral Agenesis
2c
single
C i.e. Anencephaly Neural tube defects (NTDs) i.e. anencephaly, meningomyelocele, encephalocele and spina bifidaQ can be caused by antifolate & antiepileptic drugs, maternal diabetes, lower maternal folate status, reduced activity of 5, 10, methylene - THE reductase (MTHFR) enzyme (d/t C677 T-polymorphism in MTHFR gene...
Radiology
null
bdc3f765-5e1b-4cae-899e-6bf2901e7e71
Preferred incision for abdominal exploration in Blunt injury abdomen is :
Always Midline incision
Depending upon the organ
Transverse incision
Paramedian
0a
single
• Preferred incision for emergency abdominal exploration is a long midline incision. • Bailey says “The routine approach for abdominal trauma is full midline Laparotomy” • Schwartz says “All emergency abdominal explorations are performed using a long midline incision because of its versatility.”
Surgery
null
cc7358ba-723e-4ad1-85eb-144da27a2729
Selenium sulfide is indicated for treating -
Tinea versicolor
Tinea corporis
Mixed mycotic infections
Candidiasis only
0a
single
Pityriasis versicolor or Tinea versicolor is a superficial infection of the skin caused by Malassezia furfur (Pityrosporum orbiculare). -Drugs for T. versicolor - Topical - Selenium sulfide, salicylic acid, solution containing sulfur, terbinafine cream. Oral - Ketoconazole. Tinea corporis: Oral terbinafine or itraconaz...
Microbiology
Mycology
27b28d09-a6e2-4c13-936e-bfd575de4067
Which protein is absent in saliva?
Lactoferrin
Amylase
Mucin
Intrinsic factor
3d
single
Intrinsic factor is secreted by the parietal cells of the stomach and is not secreted by the salivary glands. Lactoferrin, amylase, mucin, and muramidase are found in saliva.
Pathology
All India exam
9401ef7c-fb23-4539-baf1-95210539fdc9
An investigator into the life expectancy of IV drug abusers divides a sample of patients into HIV positive and HIV negative groups. What type of data does this division constitute?
Nominal
Ordinal
Interval
Portion
0a
single
In the question, data has been divided into two groups, i.e. HIV positive/HIV negative → Data should be measured on the nominal scale especially Dichotomous type of nominal scale.
Social & Preventive Medicine
null
0aec9501-ac1c-47b6-affe-e7c867f48735
The impact and efficiency of an iodine control program can be determined by:
Urinary iodine levels in pregnant women
Neonatal thyroxine levels
Goiter in pregnant women
Goiter in children of age 12 to 18
1b
single
Epidemic assessment is absolutely necessary before initiation of any iodination programme and is also required for the surveillance of goitre control programme. Among all the indicators set up for the assessment, the most sensitive is the neonatal hypothyroidism in order to analyze the environmental iodine deficiency. ...
Social & Preventive Medicine
null
ee0ce131-2ec3-4ae4-92a8-193be0f3ca9d
In the central nervous system (CNS), oligoden¬drocytes share a similar function with
Gemistocytes
Astrocytes
Schwann cells
Microglial cells
2c
single
Oligodendrocytes in the central nervous system (CNS) share a similar function with Schwann cells in the peripheral nervous system-synthesis of myelin. Oli­godendrocytes are small, round, lymphocyte-size cells that produce and maintain CNS myelin, which is primarily located in the white matter. Certain diseases, such as...
Unknown
null
894473e3-cbdf-490e-a342-cffca235895d
Burr cell is seen in
Uremia
Hepatocellular carcinoma
Gastric carcinoma
Ovarian cancer
0a
single
Ref Tejinder Singh 1/e p38, robbins 9/e pg 418 Other causes of microangiopathic hemolytic anemia include malignant hypeension, systemic lupus erythematosus, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and disseminated cancer. The morphologic alterations in the injured red cells (schistocytes) are st...
Anatomy
Haematology
8ec8c1f8-e811-4fb9-8b18-7de00bd2d506
Maximum content of triglycerides are found in
HDL
LDL
Chylomicrons
VLDL
2c
single
Ans. is 'c' i.e. Chylomicrons Maximum content of TG's is seen in - Chylomicrons*Maximum content of exogenous TG's is seen in -Chylomicrons*Maximum content of endogenous TG's is seen in -VLDL*Maximum cholesterol is seen in - LDL*
Biochemistry
Cholesterol and Lipoproteins
31fcb35a-e2fb-4d3c-a5d7-b9124f61196a
Which among the following is not a cause for cyanosis?
Methemoglobin
Sulfhemoglobin
Cirrhosis
Carboxyhemoglobin
3d
single
Cyanosis is caused by reduced hemoglobin. CO poisoning doesn't cause cyanosis. Approximately 5 g/dL of unoxygenated hemoglobin in the capillaries generates the dark blue color appreciated clinically as cyanosis. Causes: Central Nervous System: Intracranial hemorrhage, Cerebral anoxia Respiratory System: Pulmonary Hypee...
Medicine
null
22a2b681-1927-4bb0-85b7-34e17aa87be1
Treatment for choice for tubal pregnancy with no evidence of bleeding or rupture: September 2005
Salpingectomy
Salpingostomy
Observation
Salpingocentesis
2c
single
Ans. C: Observation There is spontaneous resolution in two third of early cases so wait and watch policy is employed in following cases: Falling hCG titre Ectopic mass less than 4 cm No evidence of bleeding or rupture Early treatment of an ectopic pregnancy with methotrexate is a ble alternative to surgical treatment. ...
Gynaecology & Obstetrics
null
952e8cd4-2469-4dc9-9f9d-7c832c064736
Which is true about the dislocation of hip joint?
Posterior dislocation is commoner
In posterior dislocation whole lower limb is rotated medially
In anterior dislocation whole lower limb is rotated laterally
All of the above
3d
multi
Posterior dislocation is the commonest dislocation. Posterior dislocation has typical deformity of flexion, adduction and internal (medial) rotation. Anterior dislocation has deformity of flexion, abduction and external (lateral) rotation.
Orthopaedics
null
a90c5541-0474-45ff-953f-ab1101f40212
Patientswith STD are asked to name other persons of either sex who move in the same socio sexual environment. These patients are then screened for the disease. This process is known as:
Cluster testing
Mass screening
High risk screening
None of the above
0a
multi
Patients of STD are asked to name other persons of either sex who move in the same socio sexual environment. These patients are then screened for the disease. This process is known as cluster testing. This technique is shown to double the cases found. Ref: Park 21st edition, page 313.
Social & Preventive Medicine
null
8812c30c-0be2-4670-be83-04e736902abf
Shine dalgarno in prokaryotes is associated with?
Transcription
Translation
Replication
Translocation
1b
single
Translation REF: Harper 27`h ed p. 372 Shine dalgarno sequence is a sequence of nucleotide bases (5 - UAGGAGG - 3) located 6-10 base upstream of AUG codon on mRNA molecule. It helps in initiation of translation in prokaryotes
Biochemistry
null
53060ead-48de-44e0-8b8d-047e1071b424
Which of the following is not a small round cell tumor?
Neuroblastoma
Retinoblastoma
Ewing's sarcoma
Hemangiosarcoma
3d
multi
Ans. is 'd' i.e., hemangiosarcomaSmall round blue cell tumors:* Histologically many of the malignant paediatric neoplasms are unique.* They tend to have a more primitive (embryonal) rather than pleomorphic anaplastic microscopic appearance.* Often characterized by sheets of cells with small round nuclei.* Frequently ex...
Pathology
null
218cdb10-7db2-48c3-b909-9e225c4dcd16
The type of receptors present on T cells are:
IgG
IgD
CD4
Prostaglandins
2c
single
Ans. is 'c' i.e., CD4(Ref: Ananthanarayan, 9th/e, p. 133 and 8th/e, p. 128)* Markers present on T cells are CD1, CD3, CD4, CD5 and CD8.
Microbiology
Immunology
53badf68-d647-44e8-8c88-c69a4709ab8b
Most common ty pe of mental retardation -
Mild
Moderate
Severe
Profound
0a
single
Ans. is 'a' i.e., Mild Category of mental retardationPercentageMild80 - 85 %Moderate10%Severe5 %Profound1 %
Social & Preventive Medicine
Mental Health
26c2063e-f5b8-46a9-a9be-078d55ea22d5
All of the following are seen in digitalis toxicity except
Ventricular bigeminy
Paroxysmal atrial tachycardia with fast ventricular rate
Regularization of atrial fibrillation
Bidirectional ventricular tachycardia
1b
multi
Digitalis has a narrow margin of safety. T Toxicity in cardiac is manifested as ventricular premature beats, pulses bigeminy, ventricular tachycardia, atrial tachycardia, atrial fibrillation, atrial flutter Most common among these is pulses bigeminy (REF. Essentials of medical pharmacology KD TRIPATHI 8th ed.)
Pharmacology
Cardiovascular system
313497ca-8ab3-44f3-ba34-cb3934f8f6a6
Incubation period of pertusis is-
1-7 days
7-14 days
15-28 days
More than 28 days
1b
single
Ans. is 'b' 7-14 days [Ref :Park 20/e, p 149 (18/e, p136, 17/e, p130, 16/e,p129))* The I.P.'s of some more diseases which are often asked in various P.G. entrance examinations are :Incubation period of Pertussis = 7-14 days*Incubation period of Diptheria = 2-6 days*Incubation period of Mumps = 2-3 wks usually 18 days*I...
Social & Preventive Medicine
Whooping Cough (Pertussis)
bf258e61-818b-4ac5-9697-f57165cef952
Which is the most common nephropathy associated with malignancy?
Membranous
MCD
IgA
FSGS
0a
single
Membranous nephropathy can be associated with tumors of the colon, lung and hematological malignancies like chronic lymphocytic leukemia
Medicine
Nephrotic and Nephritic syndrome
312b5e14-91ab-481c-a697-0e95e4960ef8
All the following factors predispose to Aoic dissection , except
Systemic hypeension
Takayasu's aeritis
1 at trimester of pregnancy
Marfan's syndrome
2c
multi
Ref Harrison 19 th ed pg 1541 Aoic dissection is the major cause of morbidity and moality in patients with Marfan's syndrome or Loeys- Dietz syndrome, and similarly may affect patients with Ehlers-Danlos syndrome. The incidence also is increased in patients with inflamma- tory aoitis (i.e., Takayasu's aeritis, giant ce...
Anatomy
General anatomy
2e32ae29-cb37-49db-bc72-4e639639775d
A child presents to the clinic with history of seizures and mental retardation. Clinical examination reveals multiple hypopigmented macules. What is the likely diagnosis:
Tuberous Sclerosis
Neurofibromatosis
Sturge Weber Syndrome
Linear epidermal nevus syndrome
0a
single
Answer is A (Tuberous Sclerosis): The presence of hvopigmented macules in the background of seizures and mental retardation suggests the diagnosis of Tuberous Sclerosis. Often hypopigmented macules are the initial clue to tuberous sclerosis, a neurocutaneous disorder inherited in an autosomal dominant manner. Any child...
Medicine
null
08559ba6-1070-4055-9dba-5210c8c8efa9
Desmosomes are helpful in connecting –
Keratinocytes
Melanocytes
Dermis and epidermis
Langerhans cells
0a
single
Desmosomes are the major adhesion complex in epidermis, anchoring keratin intermediate filaments (IFs) to the cell membrane and bridging adjacent keratinocytes, and allowing cells to withstand trauma.
Dental
null
4c0dd197-1727-4fcf-b403-522e59b7261b
MIC-2 is a marker of? -
Ewing sarcoma
Chronic lymphocytic leukemia
Mantle cell lymphoma
All of these
0a
multi
Harshmohan textbook of pathology 7th edition In Ewings sarcoma - the cell surface marker by the tumor cells of ES / PNET group is CD99 which is a product of MIC2 gene located on X and Y chromosome. .
Pathology
General pathology
5f0714e4-2298-4824-b56b-e9e37a376139
The-most common differential diagnosis of hyper-thyrodism in a young female is -
Hysteria
Essential tremor
Anxiety neurosis
Parkinsonism
2c
single
Anxiety) is a psychological and physiological state characterized by cognitive, somatic,emotional and behavioural components. Anxiety is often accompanied by physical sensations such as palpitations, nausea, chest pain, shoness of breath, diarrhaea, chills, dryness of mouth, abdominal pain and headache. Somatic signs o...
Medicine
Endocrinology
5746ca44-d168-4155-a4fc-a38f8baff1e1
All of the following statements about Sternberg Canal are true, except?
Causes intrasphenoidal meningocele
Represents persistent craniopharyngeal canal
Located anterior and medial to Foramen Rotundum
Located posterior and lateral to Foramen Rotundum
3d
multi
Sternberg's canal is located anterior and medial to foramen rotandum. It is also known as lateral craniopharyngeal canal.
Anatomy
null
9428bb5e-e8d0-4c0d-b41f-f85f7f5bbd8f
Specific stain for myeloblasts -
Sudan black
PAS
Myeloperoxidase
LAP
2c
single
The specific stain for myeloblast is myeloperoxidase And the specific stain for erythroblasts is periodic acid schiff Reference :textbook of Pathology 6th edition Author Harsha Mohan page number 362
Pathology
Haematology
d0bdabf2-3861-4e45-9fbc-9d3393fa4acd
Microfilaria is not seen in: September 2009
Lymphatics
Hydrocoele fluid
Chylous urine
Blood
0a
single
Ans. A: Lymphatics Filariasis due to Wucheria bancrofti is endemic to Southern Asia. While the laboratory diagnosis of filariasis have been conventionally made by demonstrating microfilariae in peripheral blood smear, these have also been occasionally diagnosed by cytological study of the material obtained by fine need...
Microbiology
null
167b706e-b292-4b95-8b67-4d0bf0525852
Which of the following drugs is a prodrug that after oral administration is conveed to an active agent, penciclovir
Acyclovir
Fomivirsen
Famciclovir
Ganciclovir
2c
single
Famciclovir It is an ester prodrug of a guanine nucleoside analogue penciclovir. Pharmacokinetics:- It has good oral bioavailability and prolonged intracellular t 1/2 of the active triphosphate metabolite. mech of action:- Like acyclovir, it needs viral thymidine kinase for generation of the active DNA polymerase inhib...
Pharmacology
Antibiotics
d2d78e9e-01d8-43d2-9a52-5acb54a27d99
A 3-month old male child with normal genitalia presents to the emergency department with severe dehydration, hyperkalemia and hyponatremia. The measurement blood levels of which of the following will be helpful ?
17-hydroxy progesterone
Renin
Cortisol
Aldosterone
0a
single
Ans. is 'a' i.e., 17 hydroxyprogesterone 3 month old child with normal genitalia along with salt wasting and hyponatremia suggests congenital adrenal hyperplasia due to 21 hydroxylase deficiency.Congenital adrenal hyperplasiaCongenital adrenal hyperplasia is a group of autosomal recessive disorder characterized by defi...
Pediatrics
Adrenal Gland
c5604116-250a-4d13-a42a-d58356b2453d
Which general anaesthetic selectively inhibits excitatory NMDA receptors:
Thiopentone
Halothane
Desflurane
Ketamine
3d
single
Ketamine Intravenous inducing agent. Acts by blocking NMDA receptors. Adverse effects : Hallucinations, delirium and vivid dreams are impoant adverse effects that are seen during recovery from anaesthesia (emergence delirium). Has indirect sympathomimetic action = | blood pressure, hea rate and cardiac output Increases...
Pharmacology
Anaesthesia
3f4ca3f2-0cc7-4213-8ddb-dc62a67db7a6
In AML, diagnosis of blasts cells is
10% of myeloid blasts
15% of myeloid blasts
20% of myeloid blasts
10% of myeloid blasts and 15% promyelocytes
2c
single
C. i.e. (20% of myloid blasts) (462 - Basic pathology) (418 Harsh Mohan 5th)ACUTE MYELOGENOUS LEUKEMIA* As per WHO classification of leukemias, these criteria have been revised upwards to 20% blasts in the marrow for labeling and treating a case as AML (418 - Harsh Mohan 5th)* By definition, in AML myeloid blasts or pr...
Pathology
Blood
7537be44-5ec0-470e-b9fc-c047298b91e9
Trisodium phosphonoformate (foscarnet) is a po¬tent antiviral agent for treating herpes simplex infec¬tions. It works by affecting
The viral RNA polymerase
The viral DNA polymerase
The viral reverse transcriptase
The host-cellular DNA polymerase
1b
single
Trisodium phosphonoformate (foscarnet) inhibits herpes simplex virus (HSV) replication. Foscarnet is a potent inhibitor of HSV-induced DNA polymerase, and has little effect on known cellular DNA polymer­ases. Herpesvirus mutants resistant to the drug arise easily. To a lesser extent, foscarnet also appears to inhibit t...
Unknown
null
5bf5f3a3-426d-4290-bf67-523348b005f2
The earliest discovery of a pathogenic microorganism was made by
Augustino Bassi
Pollender
Oliver Wendell
Louis pasteur
0a
single
The earliest discovery of a pathogenic microorganism was probably made by Augustino Bassi(1835), showed that the muscardine disease of silkworms was caused by a fungus.Ref: Ananthanarayan; 7th edition; Page no: 1
Microbiology
general microbiology
b90ed278-3b41-425c-ba99-6f7f4de04165
Bulging fissures in lungs is seen in –
Klebsiella pneumonia
Staph pneumonia
Pulmonary oedema
Pneumoconiosis
0a
single
The most important cause of bulging fissure is klebsiella pneumonia. Other causes are legionella pneumonia, streptococcal pneumonia, TB, Yersinia pestis, lung abscess, carcinoma bronchus
Radiology
null
608ba1f2-a6ab-4df4-83bf-cb80edd0f7d7
True statement regarding migraine in pregnancy is:
Ketorolac is preferred
NSAIDs are first line drugs
Improved symptoms with pregnancy
Sumatriptan preferred over chlorpromazine
1b
multi
Ans: (b) NSAIDs are first line drugsRef: Harrison's Principles of Internal Medicine, 19th edition, Page 2592Treatment of Acute MigraineNSAIDsNaproxen, lbuprofen,Tolfenamic acid Diclofenac, Acetominophen5-HT1 Receptor AgonistsOral: Ergotamine, Naratriptan, Rizatriptan, Sumatriptan, Frovatriptan, Almotriptan, Eletriptan,...
Medicine
Blood
4385f9d2-ff17-4069-9b23-d7ad3adad915
Expressed breast milk can be stored at room temperature for how many hoursRpt question need to be changed
4
8
16
24
1b
single
EXPRESSED BREAST MILK (EBM) STORAGEDURATIONRoom temperature6-8 hoursRefrigerator(4 C)24 hoursFreezer compament(-15 C)2 weeksDeep freezer (-18 C)3-6 months
Pediatrics
All India exam
1e641605-8e84-4fdd-8909-6306ec4b3c44
All are TRUE about Osteomalacia, EXCEPT: 1. Increased calcium 2. Increased serum phosphate 3. Normal serum calcium 4. Osteosclerotic lesions 5. Pseudofracture seen
1,2,3 & 4
2,3,4 & 5
1,2,4 & 5
4 & 5
0a
multi
Osteomalacia means softening of the bone. It is the adult counterpa of rickets and is primarily due to deficiency of vit D. This results in failure to replace the turnover of calcium and phosphorus in the organic matrix of bone. Clinical features include bone pain, muscular weakness and spontaneous fracture usually in ...
Surgery
null
60129dc5-8759-4db4-a67e-37103007a398
A pregnant 35 yrs old patient is at highest risk for the concurrent development of which of the following malignancies?
Cervix
Ovary
Uterus
Vagina
0a
single
Benign neoplasms are common in the female reproductive tract and include leiomyomas, ovarian neoplasms, and endocervical polyps. Malignancies of these organs are the most frequent cancers encountered in pregnant women, and of these, cervical cancers make up the majority.
Gynaecology & Obstetrics
Gynaecological oncology
ff8d46fa-81bc-43bb-a9db-92ac9290ae60
A patient had genital ulcer, with no blisters for which ASHA had given blue kit. After that patient presented with rash and fever. Which kit has to be given by ASHA to replace blue kit?
Gray
Red
White
Yellow
2c
single
Patient has non herpetic genital ulcer (no blisters) for which blue kit was given to cover syphilis and chancroid. Patient presented with rash and fever suggestive allergy to pencillin present in blue kit. Now it has to be replaced with white kit that contains Doxycycline instead of penicillin. Blue kit : Injection ben...
Dental
null
ca2072b7-7582-4d16-86bf-0d841b275791
False statement regarding DIC is:
Thrombocytopenia
Decreased fibrinogen
Decreased PTT
Increased PT
2c
multi
Answer is C (Decreased PTT) "TT is increased in DI DIC or Disseminated Intravascular Coagulation, is a complex thrombohaemorrhagic disorder characterized by the following sequence of events in general : Events Intravascular activation of coagulation by both intrinsic and extrinsic mechanism.deg A thrombotic phase Consu...
Medicine
null
ae6ef9a4-0444-4a06-ab7f-ed2dc954ed73
A 50 year old chronic smoker presented with cough, hemoptysis, and unexpained weight loss. CT scan revealed a tumor in the right lung invading the mediastinal pleura. The patient is likely to experience referred pain in which of the following regions?
Side of neck
Anterolateral thoracic wall
Medial pa of arm
Abdominal wall
0a
multi
The pain from the mediastinal pleura is referred to the side of the neck Pleura Innervation Pain referred to Costal and peripheral diaphragmatic pleura Intercostal nerves Thoracic or abdominal wall Mediastinal and central diaphragmatic pleura Phrenic nerve (C3, C4 and C5) Lateral neck region and supraclavicular region ...
Anatomy
Thorax
f87fb3f5-8a4f-4e50-b5a1-f1e60a8a3806
Vascular sign of narath is seen in -
Dislocation of hip
Dislocation of knee
Dislocation of elbow
Dislocation of shoulder
0a
single
Ans. is 'a' i.e., Dislocation of hip Vascular sign of Narath* Normally femoral pulse is felt in the groin against head of the femur.* In posterior dislocation of hip the vessels fall back unsupported, so femoral arterial pulsation, which is felt against the head of the femur will be feeble or even, may not be palpable.
Orthopaedics
Injuries Around Hip
3103abb3-c4af-44b5-b618-40a0a935fa52
A 45-years-old man who works in textile company visited hospital for routine health check-up. He prepares dyes in company from last 18 years. Which of the following investigation would you recommend for this patient?
Pulmonary function tests
Liver function tests
Urine examination
Complete blood count.
2c
single
Dye stuffs & dyeing industries, rubber, gas & electric cable industries are associated with carcinoma of bladder (transitional cell carcinoma). Bladder cancer is caused by aromatic amines, which are metabolized in the body & excreted in the urine. Possible bladder carcinogens are: Beta-naphthylamines, benzidine, para-a...
Social & Preventive Medicine
Environment
6da8aca5-f9c0-4d18-ba52-f7192be36df9
In Japanese Encephalitis pigs acts as:
Amplifier
Definitive host
intermediate host
Any of the above
0a
multi
(A)' Amplifier # In Japanese encephalitis, pig acts an amplifier, it doesn't manifest the disease.> Herons acts as reservoir hosts.> Human infection is a tangential 'dead end' event> Vertebrate hosts may include cattle and buffalo besides pig.
Microbiology
Misc.
a8b6d903-8e93-499f-8869-fb1f83333f13
Confabulation is?
A state of confusion where patient is not able to describe the details
Purposefully fabricating stories to project a ceain image
Filling up to gaps by fabrication to cover lapses in memory
A feeling of strangeness to familiar situations or events.
2c
single
Ans. C. Filling up to gaps by fabrication to cover lapses in memoryConfabulationIt is a type of Paramnesia (Distoed or falsified recall of events in relation to details or their temporal relationships)Unintentional filling of gaps of memory with material which are untrue and fanciful.
Psychiatry
null
1c4164ab-1264-4957-9479-b39a808a5e77
The diluent used for BCG is -
Distilled water
Normal saline
Dextrose solution
Ringer - lactate
1b
single
<p>BCG Aim- To induce a benign,aificial primary infection which will stimulate an acquired resistance to possible subsequent infection with virulent tubercle bacilli, and thus reduce the morbidity and moality from primary tuberculosis among those most at risk. WHO recommends the &;Danish 1331&; strain for vaccine produ...
Social & Preventive Medicine
Communicable diseases
fb06cdf0-c62e-4f19-9f7a-9ac646969534
Wrist drop is due Which Palsy?
Radial nerve palsy
Posterior Interossues berve injury
Ulnar nerve palsy
Carpal Tunnel Syndrome
0a
single
Ans. is 'a' i.e., Radial nerve palsy Effects of nerve palsyFeatureNerve injuredWrist dropRadial nerveFoot DropCommon peroneal nerveClaw handUlnar nerveApe thumbMedian nerve
Anatomy
Upper Extremity
edfb9317-7fa1-4a1c-80c0-320b47df2fb1
The basement membrane that separates the enamel organ and the dental papilla just prior to dentin formation is called as:
Stellate reticulum.
Outer enamel epithelium.
Membrana preformativa.
Inner enamel epithelium.
2c
multi
The basement membrane that separates the enamel organ and the dental papilla just prior to dentin formation is called the membrana preformativa.
Dental
null
f7c8f44f-0a13-49bc-ab65-843b5fd771be
'Post-moem staining' is distinguished from bruise by all EXCEPT:
Occurs in dependent pas
Edges are clearly defined
Does not appear elevated
None of the above
3d
multi
Differences between Hypostasis & Bruise Trait Hypostasis Bruise Cause Distension of capillaries & veins Rupture of blood vessels Site Over most dependent pas of body Occur at site of injury, anywhere on body Appearance No elevation of involved area Swollen, due to collected blood & oedema Epidermis Not abraded May be a...
Forensic Medicine
FMT Q Bank
b77d7b89-6ede-44b0-877b-fe086d682024
Tick borne hemorrhagic fever is seen in
Omsk hemorrhagic fever
Chandipura virus
Vesicular stomatitis virus
Yellow fever virus
0a
single
Omsk hemorrhagic fever : vector  - Tick Manifestation - Hemorrhagic fever Reservoir  -Small mammals
Microbiology
null
26100b4d-be28-4e87-bdb1-dd8f659cc63e
True regarding malathion are all of the following except: March 2008
Used as a spray
Can be used as an alternative to DDT
Most toxic of all members of the group
Belongs to organophosphorous insecticides
2c
multi
Ans. C: Most toxic of all members of the group
Social & Preventive Medicine
null
9b1d56d1-c11a-4e86-84b9-52352cbbb94b
Which of the following drug do not cross the blood-brain barrier?
Diacetyl monoxime
Obidoximine
Physostigmine
Neostigmine
3d
single
Neostigmine being a quaternary ammonium compound and highly polar cannot cross BBB.Pralidoxime which is used in OP poisoning also can&;t cross the BBB.Ref: Katzung 11th ed.Pg 121
Pharmacology
Anesthesia
65aaa955-47b2-4791-b9c2-e3272ba7b4e1
Which of the following is not associated with zinc deficiency: March 2005
Delayed wound healing
Loss of libido
Pigmentation
Sexual infantilism
2c
single
Ans. C: Pigmentation Acrodermatitis enteropathica is a rare inherited form of zinc deficiency, characterized by periorificial and acral dermatitis, alopecia, and diarrhea. Symptoms of Zinc Deficiency Poor Immune system Weight loss Intercurrent infections Hypogonadism in males Lack of sexual development in females Growt...
Medicine
null
eb4672f1-e02f-4a9d-9638-21f31eafe4a2
A child presents with seborrheic dermatitis, lytic skull lesions, ear discharge and hepatosplenomegaly; likely diagnosis:
Leukemia
Lymphoma
Histiocytosis X
Multiple myeloma
2c
single
LCH provokes a non-specific inflammatory response, which includes fever, lethargy, and weight loss. Organ involvement can also cause more specific symptoms. Bone: The most-frequently seen symptom in both unifocal and multifocal disease is painful bone swelling. The skull is most frequently affected, followed by the lon...
Pediatrics
null
4da9bdc1-219a-4c7c-9b00-3fc85feae27f
Antifolate cancer drugs are: (PGI Nov 2009)
Methotrexate
Azathioprine
Cyclosporin
Vincristne
0a
single
Ans:A (Methotrexate) Folate AntagonistMethotrexate'-'Trimethoprim4Pyrimethamine4PemetrexedMethotrexate (MTX) It is a folic acid antagonistQ that binds to the active catalytic site of dihydrofolate reductase (DHFRQ, interfering with the synthesis of the reduced form that accepts one-carbon units. Lack of this cofactor i...
Pharmacology
Anti-Neoplastic Agents
2e862800-cfe0-4d7b-a934-6afb1c0a8f48
Seal like limbs i.e. phocomelia is a specific side effect of -
Thalidomide
Cyclophosphamide
Doxorubicin
Terazocin
0a
single
Ans. is 'a' i.e., Thalidomide * Repeat from NEET Dec -16
Pharmacology
Adverse Drug Effect
992755b2-6f6b-4e88-9c27-8c3226e86076
Sphincter of Oddi consists of:
2 sphincters
3 sphincters
4 sphincters
5 sphincters
1b
single
The entire sphincter mechanism is actually composed of numerous muscle fiber sphincters and the answer stands controversial.The latest information points to a total number of three (Gray's Anatomy, edition 41), though there have been mention of four, five and still more higher number in the past. The poal for entry of ...
Anatomy
Small and Large intestine
9916b3da-f11e-4f50-a40c-d6c290f3b4fa
Petrified man is seen in:
Generalized myositis ossificans
Ehlers Danlos syndrome
Osteogenesis imperfecta
Cherubism
0a
single
Claw hand: Seen in Scleroderma  Leprosy Mucopolysaccharidosis or Hurler's syndrome or Gorgolism Mask like appearance of face: Scleroderma  Bell's palsy Grotesque or simian appearance - Pagets disease of bone. Angle face: Cherubism Petrified man: Generalized myositis ossificans (stiffness of organs) Rubber man: Ehlers...
Pathology
null