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135
dd56b7ff-ce69-49c7-a544-b54f6058f4bc
Ascending UTI caused by -
Salmonella
T.B.
E.coli
All
2c
multi
Ans. is 'c' i.e., E.coli Urinary tract infection . In the vast majority of UTIs, bacteria gain access to the bladder urethra. Ascent of bacteria from bladder may follow and is the pathway for most renal parenchymal infections. . Organisms are ? - E.coli (most common) - Serratia - N. gonorrhoea - Proteus - Pseudomonas -...
Microbiology
null
9c8fd56d-b77d-4904-8101-04707abd65b5
Nerve of anterior compament of leg ?
Superficial peroneal
Deep peroneal
Saphenous
Sural
1b
single
Ans. is 'b' i.e., Deep peroneal
Anatomy
null
9d897e8f-9b86-4a08-b032-e6afdaec7b47
Plasmodium falciparum in fection of man is characterized by -
The erythrocytes are increased in sized
All stages of erythrocytic schizogony are seen in peripheral blood
Multiple infection of erythrocytes are seen
Each erythrocytic cycle lasts 72 hours
2c
multi
P.falciparum Forms in peripheral blood-ring forms and gametocytes (crescent shaped) A) Most pathogenic B). No relapses in P.falciparum-exo-erythrocytic schizogony is absent C). Complications-pernicious malaria,black water fever D)pernicious malaria-1). Cerebral malaria-hyperpyrexia, coma,paralysis.Brain is congested.Ca...
Microbiology
parasitology
7ca88f01-529e-4f9a-a399-9b7f4732ab52
In 29 days menstrual cycle ovulation takes place at?
14th day
15th day
16th day
17th day
1b
single
ANSWER: (B) 15th dayREF: Ganong's 22nd ed p.434In a menstrual cycle the post ovulatory days remains constant, hence to calculate the day of ovulation substract 14 from the total days of cycle; i.e. in a 29 days cycle ovulation takes place on 15th day (29-14),
Physiology
Sex Hormones
e6f22617-9b42-4842-86b5-4a925665c834
The normal narrowing in the middle of the oesophagus is caused by
Azygos vein
Hemiazygos vein
Right main stem bronchus
Left main stem bronchus
3d
single
Middle constriction of oesophagus is due to left bronchus .27.5cm/11 inch from insisor teeth. BD CHAURASIA&;S HUMAN ANATOMY VOLUME 1, 6TH Edition . page no 282, fig 20.7
Anatomy
Thorax
69806de0-9070-4bc9-b377-05a797d03e28
Number of ossification centers present at bih: Punjab 08
206
250
350
450
0a
single
Ans. 206
Forensic Medicine
null
621f14b7-4bdc-40cc-821f-2199f0b56134
X-ray shows:
Fracture scaphoid
Fracture scaphoid and perilunate dislocation
Perilunate dislocation
Colies fracture
0a
single
ANS. AThis is an isolated fracture scaphoid. The main differential was the option of scaphoid and perilunate dislocation.In the X-ray provided, the alignment of radius, lunate and capitate is maintained. Hence, the answer is isolated fracture scaphoid.Important tables to revise for AIIMS1. Test for muscles around shoul...
Orthopaedics
Injuries Around the Fore Arm & Wrist
114fd8f6-5e49-480f-8154-9ef3809954cc
The antidote for Strychnine poisoning is -
Barbiturates
Physostigmine
Fomepizole .
Naloxone
0a
single
Treatment for strychnine poisoning includes: The first step is to control convulsions by keeping patient in dark room, diazepam The antidote for strychnine is short-acting barbiturates like Phenobarbital Gastric lavage with water, potassium permanganate, charcoal Acidification of urine
Forensic Medicine
null
95713bfc-18a9-498a-aa91-be67f59105f4
Sunflower cataract is associated with: September 2011
Chalcosis
Juvenile diabetes mellitus
Down syndrome
Trauma
0a
single
Ans. A: Chalcosis Sunflower cataract is associated with deposition of copper Chalcosis lentis/ Copper cataract/ Sunflower cataract A cataract caused by excessive intraocular copper. May be due to intraocular, copper containing foreign bodies Copper deposits in Descemet membrane, vitreous, internal limiting membrane of ...
Ophthalmology
null
f67081dc-21a3-4f20-99cc-2e1c62074861
Dextromethorphan should not be given with which drug?
SSRIs
MAO inhibitors
Atropine
Paracetamol
1b
single
ANSWER: (B) MAO inhibitorsREF: Katzung 12th edition page 559, KDT 6th ed page 213, 215The antitussive dextromethorphan should also be avoided by patients taking one of the monoamine oxidase B inhibitors; indeed, it is wise to advise patients to avoid all over-the- counter cold preparationsNon Opioid analgesic most comm...
Pharmacology
Opioids
95c528ca-366a-41c2-87ca-a711f187b1c8
Which mode of ultrasound help is Orbital biometry?
A- mode
B-mode
M-mode
D-mode
0a
single
A Mode Ultrasound is Amplitude Mode used for measuring Axial length of Eyeball and Orbital Biometry. A scan in Opthalmology is the A Mode Ultrasound. B mode is used in routine ultrasonography. M mode is used in chest and obstetric USG. D mode is used for vessels.
Radiology
ULTRASOUND
4c9bc0a5-07b4-408d-81aa-8e26e728deae
Most common frequency of Tuning fork used in ENT:
256 Hz
512 Hz
1024 Hz
2048 Hz
1b
single
Ans. (b) 512 HzRef: Dhingra's ENT 5th ed. / 26* Tuning fork test can be performed using tuning fork of different frequencies such as: 128, 256, 512, 1024, 2048, 4096 Hz.* MC used/ ideal for routine clinical practice is of 512 Hz.* Tuning fork of lower frequencies produce sense of bone vibration while those of higher fr...
ENT
Diagnostic & Operative ENT
2818965b-9d48-40e0-8254-c5c3b4569064
To examine the vaginal cells in the rape accused, the test used is
Lugol's iodine test
Takayama test
Florence test
Precipitin test
0a
single
Lugol's iodine test is to detect vaginal epithelial cells containing glycogen. Takayama test is to detect blood stains; while Florence test is test for seminal stain.
Forensic Medicine
Sexual offences
2b4c65df-734f-4e29-b2f5-f896b77fa820
Which of the following conditions characterised by episodes of excessive and uncontrolled eating :
Anorexia nervosa
Bulimia nervosa
Body dysmorphobia
All of the above
1b
multi
B. i.e. Bulimia nervosa
Psychiatry
null
9e898dd3-d40b-46b5-b3a2-3d8f4f0a0a9e
Glutaraldehyde is used for all of the following EXCEPT:
Bronchoscope
Thermometer
Proctoscopes
Endoscopic tubes
1b
multi
Ref: Textbook of Diagnostic Microbiology, E-book, P 67* High level of disinfectant: 2% glutaraldehyde for 20 minutes for all instruments coming in contact with mucous membrane. Like bronchoscope, proctoscope, endoscopic tubes, etc.* Intermediate level of disinfectant: Phenol or alcohol is used to disinfect thermometer....
Microbiology
General
c0a15c33-0d57-467f-9c65-766a5fdc9317
Raygat's test is based on:
Weight of lung
Specific gravity of lung
Consistency of lung
Volume of lungs
1b
single
Hydrostatic test/ Raygat's test: Principle: Specific gravity of lung before respiration is 1.04-1.05 and it becomes 0.94-0.95 after respiration. This makes the respired lung to float. Procedure: Dissect out the fetal lungs & Put into a trough of water and observe. Liver is used as control Inference: If they sink--unres...
Forensic Medicine
Infant deaths & child abuse
e98dfeb3-f46c-41dd-9c27-b88ead087f66
Most common site for nasopharyngeal carcinoma is
Nasal septum
Fossa of rosenmuller
Vault of nasopharynx
Antero-superior wall
1b
multi
The commonest site of origin in the nasopharynx is the fossa of Rosenmuller. Anterior spread causes blockage of choana and nasal cavity and inferior spread are towards oropharynx and hypopharynx, lateral spread involves parapharyngeal space and infratemporal fossa through the sinus of Morgagni, an upward spread is towa...
ENT
Pharynx
9ae20aef-97b4-426f-bdda-8bd55a0b8b9e
Dr. Sunil used edrophonium for differentiating a myasthenic crisis from the cholinergic crisis. He preferred it over other anticholinesterase agents because of its:
Shorter duration of action
Longer duration of action
Direct action on muscle end plate
Selective inhibition of true cholinesterase
0a
multi
Edrophonium- Short-acting anticholinesterase. In Myasthenia gravis, edrophonium improves the condition.
Pharmacology
null
5bbf7709-3173-4038-9e82-1a3fb77eab4f
Treatment for pagets disease of breast is
Simple mastectomy
Radical mastectomy
Microdochectomy
Hadfeilds operation
0a
single
Simple mastectomy along with lymph node assessment is usually treatment of choice.
Surgery
null
ad8e878b-9ccf-44fa-a87b-d1c3147d3bec
The following test is not used for diagnosis of leprosy:
Lepromin test
Split skin smear
Fine needle aspiration cytology
Skin biopsy
0a
single
Ans. is 'a' i.e., Lepromin test: Lepromin test is not used for diagnosis:Lepromin test: It is an intradermal test with biphasic response and demonstrates the delayed type of hypersensitivity.(a) Early reaction of Fernandez: It occurs in 24-48 hours.(b) Late reaction of Mistuda: It peaks in 4 weeks and is more meaningfu...
Microbiology
Bacteria
03c1b0b2-449d-46c0-8f60-0d787ed4a555
Hyperbaric oxygen is useful in ?
Tetanus
Gas gangrene
Frostbite
Vincent's angina
1b
single
Ans. is 'b' i.e. Gas gangrene The Undersea and Hyperbaric Medical Society (UHMS) currently recognizes hyperbaric oxygen therapy (HBO) as an approved therapy for 13 pathologic entities. These are conditions for which HBO has substantial scientific suppo demonstrating therapeutic benefit. Hyperbaric oxygen is currently c...
Surgery
null
45507ecb-55dd-46bb-85c0-887cb3ff313e
25 years old 2nd gravida with B negative blood group reaches in labour room in full dilatation. All the following norms to be followed except
Cord blood to be saved in 2 l - plain & EDTA l
Early clamping of cord
Avoidance of manual removal of placenta
Liberal prophylactic use of ergometrine
3d
multi
Use of ergot derivatives is contraindicated in Rh negative mother to avoid chances of feto-maternal micro transfusions. ref Katzung 12 th ed.
Pharmacology
All India exam
bdb46033-43e3-4a6b-8f3b-6facad0aa9c2
A 50 year old male, Ram Lal suffering from renal failure, underwent a kidney transplant. He was prescribed a nucleotide derivative following the organ transplant. The nucleotide derivative of therapeutic importance in this organ transplant is :
Azathioprine
5–Fluorouracil
Cytarabine
Allopurinol
0a
multi
Immunosuppressants are used in organ transplantation to prevent the rejection. Most commonly used agents for this purpose are glucocorticoids. Azathioprine is a nucleotide derivative that can be used as an immunosuppressant. 5-Fluorouracil and cytarabine are also nucleotide derivatives but these are used for the treatm...
Pharmacology
null
ed8bb69c-4018-4f22-96b4-e0c4ada90a18
All of the following are seen in MEN IIB except?
Hyperparathyroidism
Neuromas
Medullary carcinoma
Pheochromocytoma
0a
multi
Hyperparathyroidism
Pathology
null
addddf42-5405-4237-ad52-6272b38bbfcc
Which among the following is not true for Hemophilia A
APTT - Decreased
Factor VIII - Decreased
Factor IX - Normal
VWF - Normal
0a
multi
Hemophilia A Bleeding time - Normal  APTT - Increased Factor VIII - Decreased  Factor IX - Normal  VWF - Normal
Pathology
null
f88788b6-8fcc-4f26-b53a-fa9ef975d6c9
In management of thyroglossal cyst
Nodes of neck are removed
Sternocleidomastoid muscle is dissected
Central poion of thyroid is excised
Subtotal thyroidectomy is done
2c
single
Thyroglossal cyst is managed by Sistrunk operation in which the cyst is completely excised along with the thyroglossal tract. Since the thyroglossal tract is intimately related to the hyoid bone, the central poion of the hyoid bone is also removed. Ref : S. Das Op. Surgery 4/e p201
Anatomy
Head and neck
bc77b39a-832e-4411-b2a8-f892b15ba64f
Which fluoroquinolone is highly active against Mycobacterium leprae and is being used in alternative multidrug therapy regiments:
Norfloxacin
Ofloxacin
Ciprofloxacin
Lomefloxacin
1b
single
(Ref: KDT 6/e p756) R:Rifampicin O:Ofloxacin M:Minocycline Nowdays, even single lesion leprosy is treated as paucibacillary leprosy
Pharmacology
Other topics and Adverse effects
ecb3e08a-25a7-47e8-ad9d-dd10d9d56932
C.E.A. (Carcinoma embryonic antigen) is elevated in all except -
Alcoholic Cirrhosis
Ca-colon
Ulcerative Colitis
Emphysema
3d
multi
Ans. is 'd' i.e., Emphysema
Pathology
null
6cb02737-eabe-4dc3-8211-244b580e62b3
Abdominal ultrasound of a patient showed gall bladder with diffuse wall thickening and hyperechoic nodules at the neck and few comet tail aifacts. What is the most likely diagnosis?
Adenomyomatosis
Adenocarcinoma of gall bladder
Xanthogranulomatous cholecystitis
Chelesterol crystals
0a
multi
Adenomyomatosis is a benign condition characterized by hyperplastic changes of unknown etiology involving the gallbladder wall. It causes overgrowth of the mucosa, thickening of the muscular wall, and formation of intramural diveicula or sinus tracts termed as Rokitansky-Aschoff sinuses. Ultrasound shows a thickened ga...
Surgery
null
b12f08bf-1399-4e69-85c3-28add54ee19c
M/C gene nutation in fibroid.
MED-12
COL 4 A5-A6
FH
None of above
0a
multi
Ans. is a, i.e. MED-12(Ref: Williams Gynae 3rd/ed, p203)The 2 M/C gene mutations in fibroid are* MED-12 mutation* HMGA2 gene mutation
Gynaecology & Obstetrics
Miscellaneous (Gynae)
f4c7c526-0fad-4808-a88e-1499df048f2b
Uncontrolled flailing of an arm is a symptom of?
Amyotrophic lateral sclerosis
Lower motor neuron syndrome
Dysdiadochokinesias
Hemiballismus
3d
multi
Hemiballismus is associated with a lesion of the sub thalamic nucleus of the motor system. Lesions in this nucleus produce uncontrolled flailing and involuntary movement, especially of the upper extremity. Amyotrophic lateral sclerosis, a disease of the lower motor neurons, produces weakness in skeletal muscles, which ...
Unknown
null
8cad31ab-0128-4f72-a077-6e7873867bf7
Pulmonary tuberculosis is more common in the following asssoctiated diseases except
Aids
Diabetes
Chronic renal failure
Mitral stenosis
3d
multi
Refer Pg 367 Pulmonary tuberculosis is defined as an active infection of the lungs (latin pulmo = lung). It is the most impoant TB infection, because an infection of the lungs is highly contagious due to the mode of droplet transmission.
Anatomy
Respiratory system
1248e6b4-8a3a-4f92-a49c-7638d9654e33
IL 1 causes
Increased leukocyte adhesion
Fibroblast proliferation
Increased collagen synthesis
All the above
3d
multi
Ref Robbins 9/e p87 IL-1 is intensely produced by tissue macrophages, monocytes, fibroblasts, and dendritic cells, but is also expressed by B lymphocytes, NK cells, microglia, and epithelial cells. They form an impoant pa of the inflammatory response of the body against infection. These cytokines increase the expressio...
Anatomy
General anatomy
333b5ce0-b50d-4cc2-85c6-885190d3bfe2
Additional daily energy requirement during the first six months for a lactating woman is ?
350 K calories
450 K calories
550 K calories
None
3d
multi
Ans. is 'None' Additional daily energy requirement during first six months of lactation is+- 600 Kcal/day.
Social & Preventive Medicine
null
d5cfa415-697e-4c65-89b9-aaf5ccafe5c3
The tapeworm that can be transmitted directly from human to human is
Fish Tapeworm
Beef Tapeworm
Dog Tapeworm
Dwarf Tapeworm
3d
single
The adult Hymenolepis nana worm is very small, at perhaps 4 cm in length. The so-called "dwarf tapeworm" is the only tapeworm that can be transmitted directly from human to human.Eggs are ingested the fecal-oral route. They then release embryos that penetrate the intestinal wall. The resulting cysts mature in the intes...
Microbiology
parasitology
e3838de1-a4fc-49bd-a2e6-633f2e691a3a
Most common nerve damaged in CSOM is(REPEAT QUESTION)
III
VII
II
VI
1b
single
Facial paralysis occurs as a complication of both acute and chronic otitis media. (Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 88)
ENT
Ear
7b215459-4356-4055-a1b3-69a1e1b08c56
Drug used in the treatment of gastric ulcer due to H. pylori is:
Anticholinergics
Carbenoxolone sodium
Bismuth sub citrate
Coicosteroid
2c
single
Bismath taken as suspension it is thought to act by decreasing PG synthesis in the intestinal mucosa there by reducing cl secretion ESSENTIALS OF MEDICAL PHARMACOLOGY SEVENTH EDITION kD TRIPATHI Pg no.686
Pharmacology
Gastrointestinal tract
b0f5d8eb-eda4-48a2-ad59-d158d8132c16
A pregnant female delivered a baby with normal expulsion of an intact placenta. After half hour she staed bleeding per vaginaly. On examination she was hypotensive and boggy mass is palpated per abdomen. USG showed retained placental tissues. what is the likely diagnosis?
Placenta succenturiata
Adenomyosis
Placenta accreta
Membranous placenta
0a
single
Ans: A. Placenta succenturiataRef: DC Dutta's tubook of Obstetrics, gh ed.Placenta succenturiata has one (usual) or more small lobes of placenta placed at a varying margin from the main placental margin.A leash of vessels connects the small lobe with the main lobe.Many times, succenturiate is retained and it presents a...
Gynaecology & Obstetrics
null
5967895f-321c-4d73-958a-b59f83d14fe2
Commonest cancer in burn scar is
Squamous cell carcinoma
Fibrosarcoma
Adenocarcinoma
Adenosquamous carcinoma
0a
single
The commonest cancer associated with burns is squamous cell carcinoma. This is also known as marjolin's ulcer and this malignancy sta from the scar tissue of burns. Treatment is wide local excision, in case of large ulcer, amputation is required. Reference : SRB's Manual of Surgery, 6th Edition, page no = 283.
Surgery
General surgery
25b0ff74-fa10-4430-9dab-90cf74394e6f
True or false regarding muscles of tongue A. Palatoglossus arises from palatine aponeurosis and descends in the palatoglossal arch B. Hyoglossus protrudes the tongue forwards C. Genioglossus arises from upper genial tubercle of mandible and it’s upper fibers retract the tongue D. Styloglossus is inserted onto dorsum of...
A - True, B - True, C - False, D - True, E - True
A - False, B - False, C - True, D - False, E - True
A - False, B - True, C - False, D - True, E - False
A - True, B - False, C - True, D - False, E - True
3d
multi
Genioglossus is the protruder of tongue. Styloglossus is inserted into sides of tongue.
Anatomy
null
6545d43b-1be5-4747-857e-c38979c8b579
Which of the following is used for the treatment of Myopia?
Nd-YAG Laser
Excimer Laser
Harmonium Laser
Argon Laser
1b
single
Treatment of Myopia A) Methods to flatten central corneaSurgeryRange of MyopiaRadial keratotomy 1--6 DPhotorefractive keratotomy 1 - 6 DAutomated lamellar keratectomy6 - 32 DExcimer Laser Assisted Insitu Keratomileusis 2 - 12 D ( upto 30 D )LASEK 1 - 6 D Intracorneal rings 1 - 6 D B) Methods to reduce overall refractor...
Anatomy
All India exam
1fc830c8-fdc6-4255-a85c-ce9e3ad910f5
The purpose of heating gold foil before condensing is:
To improve welding quality
To melt the gold
To remove adsorbed gases on gold surface
To increase oxidation
2c
single
Gold attracts gases that render it noncohesive, such gases must be removed from the surface of the gold before dental compaction. This process is usually referred to as degassing or annealing and is accomplished by application of heat.
Dental
null
99d1e511-c629-49e2-8deb-28becc9357e0
A 80-year-old patient presents with a midline tumor of the lower jaw, involving the alveolar margin. He is edentulous. Treatment of choice is:
Hemimandibulectomy
Commando operation
Segmental mandibulectomy
Marginal mandibulectomy
2c
single
Mandibulectomy Marginal Mandibulectomy Segmental Mandibulectomy Conservative mandibulectomy Paial excision of the superior poion of mandible in veical phase Inner coical surface and a poion of underlying medullary cavity is excised Preserve mandibular continuity Indicated when Tumor lies within 1 cm of the mandible or ...
Surgery
Oral cavity
10635b7d-f392-4099-bb65-06194a9183f5
Malunion of the supracondylar fracture of the humerus in children results
Flexion deformity
Extension deformity
Cubitus varus deformity
Cubitus valgus deformity
2c
single
(Cubitus varus deformity) (599-Apley's 8th)* Malunion is the commonest complication of a supra condylar fracture and results in a cubitus varus deformity (Gun-stock deformity)* This is because the fracture unites with the distal fragment tilted medially and in internal rotation* Cubitus valgus deformity results from fr...
Orthopaedics
Injuries Around Arm & Elbow
2965344e-9707-46aa-8bd0-48e8f754b8aa
Burkholderia cepacia is intrinsically resistant to
Ciprofloxacin
Polymyxin
Cotrimoxazole
Ceftazidime
1b
multi
(B) Polymyxin[?]BURKHOLDERIA CEPACIA COMPLEX is a group of Gram negative, catalase positive and lactose non fermenting species (nine species).oThis microrganism causes pneumonia in immunocompromized patients and lung disease in patients affected by cystic fibrosis or chronic granulomatosis disease.oPathogenesis: organi...
Pharmacology
Anti Microbial
7e02d85b-5050-444e-a8b9-c578aa48f41d
Without external cue, the sleep-wake cycle in humans
Unchanged
Continues with cycle length of > 24 hours
Continues with cycle length of < 24 hours
Continue with cycle length of > 12 hours
1b
single
Normal sleep-wake cycle in humans- 24 hrs When external cues (Light and darkness) removed, sleep-wake cycle- Slightly increased (>24hrs)
Physiology
null
7fb5cdec-e91e-4abd-9a70-6c0e2b62fa55
Which of the following is NOT transmitted by Aedesaegypti -
Filariasis
Yellow fever
Dengue fever
Chikungunya Hemorrhagic fever
0a
single
Ans. is 'a' i.e., Filariasis Filariasis is rarely transmitted by Aedes Aegypti mosquito. It is usually transmited by culex mosquito.
Social & Preventive Medicine
null
f0b60d73-f4e4-46e9-a366-047c96292236
Opsoclonus is associated with -
Neuroblastoma
Nephroblastoma
Retinoblastoma
Hypernephroma
0a
single
Ans. is 'a' i.e., Neuroblastoma o Opsolonus is seen primarily in Neuroblastoma.o Neuroblastoma is embryonal cancer of peripheral sympathetic nervous system,o Thirst most common childhood cancer (lst - leukemia, 2nd - Brain tumor),o MC diagnosed neoplasm in infancy.o Arises in abdomen either in adrenal gland or retroper...
Pediatrics
Blood
f4669d59-b062-4569-8797-c636f8e62aec
Mechanism of action of Calcitriol is:
Decreased calcium resorption calcium from bone
Increase calcium absorption from intestine
Decreased calcium absorption from kidney
Decrease calcium absorption from intestine
1b
single
Calcitriol is a synthetic version of Vitamin D3 used to treat calcium deficiency with hypoparathyroidism Bone-calcitriol increases resorption of calcium from bone.kidney-it increases calcium reabsorption in the distal tubule.intestine-it promotes intestinal absorption of calcium (Ref.Essentials of medical pharmacology ...
Pharmacology
Endocrinology
3f1d5e21-914e-42d5-a4a0-5499789a753f
Interocclusal distance is required because
It is essential in complete denture construction
It permits supporting tissues to rest
It helps in mounting casts
None of the above
1b
multi
The interocclusal distance is a necessity, when the mandible is at rest, as it permits supporting hard and soft tissues to rest.
Dental
null
2f79e6c4-8168-47d2-abcb-ed12189f0641
Suicide tendency are common in
Mania
Depression
Schizophrenia
Obsessive compulsive disorder
1b
single
B. (Depression) (236- 37 - Neeraj Ahuja 6th)SUICIDE is a type of deliberate self harm (DSH) and is defined as a human act of self - intentioned and self inflicted cessation (death) It ends with a fatal out comeRISK FACTORS FOR SUICIDE1. Age > 40 years2. Male sex3. Staying single4. Preveious suicidal attempts5. Depressi...
Medicine
Psychiatry
f34cfaed-f535-4894-bae4-b72232493dbb
True about H mole:
Always associated with raised uterine size for gestational age
Raised hCG
Hysterectomy in selected cases
Chemotherapy is the treatment of choice
1b
multi
Symptoms Amenorrhea of varying duration followed by bleeding Passage of vesicles per vaginum Hyperemesis is common due to high levels of circulating hCG(refer pgno:169 sheila obstetrics 2 nd edition)
Gynaecology & Obstetrics
General obstetrics
96a00895-ae1f-43e2-9a11-8e376b3f1121
Where is the Cave of Retzius present
Between urinary bladder and rectum
Between urinary bladder and cervix
In front of the bladder
Between the cervix and the rectum
2c
single
The retropubic space (also known as the prevesical space or cave of Retzius) is an extraperitoneal space located posterior to the pubic symphysis and anterior to the urinary bladder. It is separated from the anterior abdominal wall by the transversalis fascia and extends to the level of the umbilicus. Ref - BDC 6e vol2...
Anatomy
Abdomen and pelvis
598bf44e-2195-4c3b-9ab1-d3b4d014160a
Lymphatic drainage of upper outer quadrant of breast is
Anterior axillary
Posterior axillary
Paratracheal
Apical
0a
single
MAMMARY GLAND:- Modified sweat gland in superficial fascia of pectoral region. Rudimentary in males. Located in superficial fascia. Extend: veically- 2nd to 6th rib Horizontally- lateral border of sternum to mid axillary line. LYMPHATIC DRAINAGE:- Lymph nodes:- 1. Axillary-anterior, posterior, central and lateral. 2. I...
Anatomy
Upper limb
3d53ec70-677d-4608-b7c9-b91c0ebc1780
A 42 -year old man was referred with a 2 week history of fever weakness and bleeding gum. Peripherial smear showed pancytopenia. The bone marrow examinationrevelaed 26% blasts frequently exhibiting Auer rods andmature myeloid cells. An occasional neutrophil withpseudo Pelger-Huet anomaly was also noted : Which ofthe fo...
Acid phosphatase
Non specific esterase.
Myeloperoxidase
Toluidine blue.
2c
single
Myeloperoxidase
Pathology
null
bd3e863f-43a1-429c-9926-62e6c03cd28b
Butcher's thigh is?
Vastus lateral rupture
Subcutaneous lipodermatosclerosis
Bursa in adductor canal
Accidental injury to major vessels in thigh or groin
3d
single
Accidental injury to major vessels in thigh or groin REF: Bailey & Love's Sho practice of surgery 18th edition Page 147, 69 (in older editions) Butcher's thigh is penetrating wound of femoral triangle due to knife slipping while boning meat. Penetrating wound involving main veins in the thigh or groin are potentially f...
Surgery
null
649d4155-bf2e-4c89-bf80-7b2df4049f25
A 30 year old presented with a skin lesion in his right axilla. A presumptive diagnosis of staphylococcal skin carbuncle is made & patient is treated with empiric trimethoprim/ sulfamethoxazole. After 2 days, the patient came to emergency with excessive weakness, abdominal pain & dark coloured urine. O/E- vitals are no...
Glucose 6-phosphate dehydrogenase (G6PD) deficiency
Hemolytic-uremic syndrome
Hereditary spherocytosis
Iron deficiency anaemia
0a
single
PBF shows bite cells, anisocytosis, and spherocytes with jaundice after receiving sulfamethoxazole which makes the diagnosis of glucose 6-phosphate dehydrogenase (G6PD) deficiency. Triggers for acute haemolytic anemia in G6PD deficiency: Fava beans Infections Drugs- primaquine, dapsone, sulfamethoxazole, and nitrofuran...
Medicine
Sickle Cell Disease, G6PD deficiency and other Hemolytic Anemia
f6d33b92-c5c6-48ff-9eeb-aa5a5a5b27ff
Potential Support Ratio (PSR) is defined as
Number of persons aged 15 to 65 per children below 15 years
Number of person aged 15 to 65 per one older person aged > 65 and younger person < 15 years
Number of persons aged 15 to 65 per one older person aged >/= 65 years
Number of persons aged 15 to 65 persons older person aged > 60 and younger person < 15 years
2c
single
Number of persons aged 15 to 65 per one older person aged more than or equal to 65 years
Social & Preventive Medicine
null
3d25422a-6d9c-416a-9e9b-bdf8740cd733
All of the following statements are true about congenital rubella except
It is diagnosed when the infant has IgM antibodies at bih
It is diagnosed when Ig G antibodies persist for more than 6 months
M.C. congenital defects are deafness, congenital hea disease and cataract
Infection after 16 weeks of gestation result in major congenital defects
3d
multi
The risk of congenital defects has been estimated at 90% for maternal infection before 11 wks of gestation,33% at 11-12 wks ,11% at 13-14 wks, and 24% at 15-16 wks Defects occuring after 16 wks of gestation are uncommon ,even if fetal infection occurs. The fetus is completely spared if infection occurs beyond 16 weeks....
Pediatrics
Infectious disease
11134792-0f4f-4322-b385-2a9ab568e6dc
When gases flow through an orifice which factor is least likely to effect turbulence
Density of gas
Viscosity of gas
Pressure of gas
Diameter of orifice
2c
single
Pressure of the gas is least likely to affect the turbulence Ref: guyton and hall textbook of medical physiology 12 edition
Physiology
Respiratory system
0dbac2bb-fee5-4794-8904-103dc1e57aff
A 50yrs old diabetic patient presented to ENT OPD with Intense pain, sudden loss of Vision. On examination patient has palatal perforation along with Blackish debris within Nasal cavity. What could be the most probable causative agentt for this condition?
Aspergillus
Mucor
Candida
Cryptococcus
1b
single
Diabetic patient with vision loss and blackish necrotic debris : Typical of Rhinocereberalmucormycosis. Mucor is most common fungal organism to invade orbit & result in Orbital cellulitis along with Fulminant fungal sinusitis O Mucor causes rhinocerebral disease. O Due to invasion of blood vessels, mucor fungus causes ...
ENT
Fungal Rhinosinusitis
a449025b-2ae3-4aab-8df7-5804d61800b7
Radiation produces its effect on tissue by
Coagulation of cytoplasm
Increasing the temperature
Charring of nucleoprotein
Hydrolysis
2c
single
C i.e. Charring of nucleoprotein Radiotherapy is treatment of malignant tumors with ionizing radiation (m.c. y rays)Q ; which causes excitation or ionization (ejection of electron from orbit) of electronQ and kills tumor cells by producing double strand breaks in DNA (direct) or free radicles (indirect). So ionizing Ra...
Radiology
null
7b6c326f-598d-4939-b224-28e87bc65f61
A patient in ICU was started on atracurium infusion. He developed seizure on day 3. What is the most likely cause?
Accumulation of atracurium in the body
Accumulation of Laudanosine in the body
Release of histamine
Hepatotoxicity of atracurium
1b
single
ANSWER: (B) Accumulation of laudanosine in the bodyREF: Longneckers anaesthesiology Ch 33, Stoelting's Pharmacology & Physiology in Anesthetic Practice 4th Ed Ch 8Atracurium undergoes elimination via 2 pathways- spontaneous Hoffman's elimination (chemical mechanism) & degradation by non-specific esterases (biologic mec...
Anaesthesia
Non-depolarising Neuromuscular Blocking Agents
35399572-4e81-45f5-8087-becbe709bd9b
An African presented with itching with rashes and inguinal lymph nodes. Skin snips shows microfilariae which are non-sheathed. The most probable organism will be:
Wuchereria bancrofti
Brugia malayi
Brugia timori
Mansonella streptocerca
3d
single
Mansonella streptocerca is transmitted by biting midges. The major clinical manifestations involve the skin and include pruritus, papular rashes, and pigmentation changes. Many infected individuals have inguinal adenopathy, although most are asymptomatic. The diagnosis is made by detection of the characteristic microfi...
Microbiology
null
ccbde92b-5824-43eb-8c04-4497fde21c69
For side to side movement at neck which of the following joint involved (2019)
Atlanto - axial joint
Atlanto -occipital joint
Occipital -axial joint
C6 - C7 aiculation
0a
single
.
Anatomy
All India exam
f87c09b7-213b-4365-ab4c-8dfe9892c761
For which one of the following tumors Gastrin is a biochemical marker :
Medullary carcinoma of thyroid
Pancreatic neuroendocrine tumour
Pheochromocytoma
Gastrointestinal stromal tumor
1b
single
Ans. is 'b' i.e., Pancreatic neuroendocrine tumor Gastrin is secreted by Gastrinomas.Gastrinomas are neuroendocrine tumors found in the duodenum (50 to 70%) pancreas (20 to 40%) andOther intraabdominal sites (mesentery, lymph nodes, biliary tract, liver, stomach, ovary)Excess gastrin secretion leads to Zollinger Elliso...
Unknown
null
7ae477a1-13d3-4ee2-8b64-75313fc6b05c
Intercostal nerve is a branch of ?
Brachial plexus
Dorsal rami of thoracic spinal nerves
Ventral rami of thoracic spinal nerves
Ventral rami of cervical spinal nerves
2c
single
Ans. is 'c' i.e., Ventral rami of thoracic spinal nervesVentral rami of upper 11th thoracic spinal nerves are known as intercostal nerves and ventral ramus of T12 is known as subcostal nerve.Upper six intercostal nerves supply thoracic wall whereas lower five intercostal nerves and subcostal nerve supply thoracic and a...
Anatomy
null
838959e9-553c-4d4b-8f26-a0a0b047f16d
The most common association of renal failure in obstetrics is?
PIH
Sepsis
Abruptio placentae
HELLP syndrome
0a
single
Ans. A. PIH. (Ref Williams Obstetrics. 22nd ed. Chapter 48; pg. 1255-1258; Table 48-6).Today, renal failure is most often associated with severe preeclampsia - eclampsia [with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) developed renal failure).Obstetrical hemorrhage, notably placental abrupti...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
efd14f79-c0d6-482e-96a4-0ecfb012f9c9
In which of the following situations can air abrasion not be used?
Caries excavation
Debriding pits and fissures
Cavity preparation
Stain removal
2c
single
Although promoted for caries excavation, air abrasion is not able to produce well-defined preparation wall and margin details that are possible with conventional rotary cutting techniques. Ref: Sturdevant's art and science of operative dentistry. 4th edition page 328
Dental
null
c25005af-82e4-4811-93b4-eafbbdd8046c
The reaction that occurs when antibody and soluble antigen are mixed is demonstrated by the
Agglutination test
Precipitin test
Hemagglutination test
None of the above
1b
multi
In precipitation test, antibody combines with soluble antigen. While in agglutination test, antibody combines with insoluble antigen
Microbiology
null
93b8520f-9c68-4ec4-a187-8741767adabc
The parvocellular pathway from lateral geniculate nucleus to visual coex is most sensi ve for the stimulus of
Color contrast
Luminance contrast
Temporal frequency
Saccadic eye movements
0a
single
Color contrast Parvocellular pathway - Color vision, texture, shape, fine detail Magnocellular pathway - Detection of movement, depth, flickers
Pathology
All India exam
ea7b19b5-97d7-4832-a7ec-de1871123514
Most frequent cause of neonatal thrombocytopenic purura is –
Infection
Drug idiosyncrasy
Large haemangiomas
Erythroblastosis
0a
single
Amongst the given options, only infection causes neonatal thrombocytopenia
Pediatrics
null
f31effa4-48b0-48ad-8e28-711359bb837f
Children are more susceptible than adults to the following action of atropine
Cycloplegic
Gastric antisecretory
Central excitant and hypehermic
Tachycardia
2c
single
PHARMACOLOGICAL ACTIONS (Atropine as prototype) Body temperature:- Rise in body temperature occurs at higher doses. It is due to both inhibition of sweating as well as stimulation of temperature regulating centre in the hypothalamus. Children are highly susceptible to atropine fever. Ref:- kd tripathi; pg num:-115
Pharmacology
Autonomic nervous system
0c4c8239-53c7-4c27-b9c4-11add8cc0198
Onion peel appearance on radiograph is not seen in
Garre's osteomyelitis
Ewing's sarcoma
Osteogenic sarcoma
Fibrous dysplasia
3d
single
Fibrous dysplasia-  The normal radiolucent maxillary sinus may be partially or totally replaced by the increased radiopacity of  this lesion. The degree of radiopacity depends on its stage of development and the relative amounts of bone and fibrous tissue present. Usually the radiopaque areas have a uniform characteris...
Radiology
null
6c2c37b2-f492-497c-9721-51d13f89e1f0
In a patient with renal cell carcinoma with a thrombus in the IVCrenal vein, which of the following is the best for diagnosis?
CT scan
Angiography
Colour Doppler imaging
IVP
0a
single
Ans. CT scan
Radiology
null
c83033be-704e-4532-b0dd-c2b1632b29ee
Mean bone density amongst two groups of 50 people each is compared with each other. The test of significance used would be:
Paired-t-test
Student t-test
Analysis of variance
Chi-Square test
1b
single
Ans. is 'b' i.e. Student t-test Let's first revise the various statistical tests:Chi-Square test:Chi-square test is used for qualitative data; data in which there is no notion of magnitude or size of the attribute.The data are classified by counting the individuals having the same characteristic or attribute (i.e. pers...
Social & Preventive Medicine
Statistical Tests
5e9ed470-12cd-4b13-a77c-3e8c8dda1daa
All of the following modalities can be used for in situ ablation of liver secondaries , except
Ultrasonic waves
Cryotherapy
Alcohol
Radio-frequency
0a
multi
Ultra sonic waves are not described as a method of local Ablative therapy for liver secondaries Local ablative therapy for liver secondaries Crypotherapy Radio-frequency or microwave ablation Ethanol, acetic acid, chemotherapy, hot saline Ref: Sabiston 20th edition Pgno :1464-1465
Anatomy
G.I.T
6f29c290-78b7-4357-b80d-de5555d52743
Xanthelasma bulbar all are true EXCEPT:
Dots occurring on lateral side of eye
Occur in middle aged women
Creamy yellow in color
Associated with Diabetes
0a
multi
ANSWER: (A) Dots occurring on lateral side of eyeREF: Khurana 4th ed p. 359XANTHELASMA BULBAR:Creamy yellow plaquesInvolve skin over inner canthusIn middle aged womenAssociated with diabetes and hypercholestrolemia
Ophthalmology
Degenerative Conditions
e2a08164-9683-4e7e-b860-771e1e6cda66
Most common infections after splenectomy are
Capsulated bacteria
Uncapsulated bacteria
Gram positive sepsis
Gram negative bacteria
0a
single
Oppounist post-splenectomy infection is caused by capsulated bacteria.Post-splenectomy septicaemia may result from Streptococcus pneumoniae, Neisseria meningitides, Haemophilus influenzae and Escherichia coli.Bailey and love 26th edition pg: 1096
Surgery
G.I.T
7c819c8c-5fee-43d0-91bb-f2803d6922cf
Most common site of carcinoma esophagus is:
Middle 1/3rd
Upper 1/3rd
Lower 1/3rd
Lower end of esophagus
2c
single
Answer is C (Lower 1/3rd) The lower third of the esophagus is the most common site of esophageal cancer and accounts for about 50% of all esophageal cancers. `About 15% of esophageal cancers occur in the upper third of esophagus (cervical esophagus), 35% in the middle third of esophagus and 50% in the lower third' - Ha...
Medicine
null
fa4dd961-1e75-44c0-bcc9-94a4560ef908
The placenta is anchored to the myometrium partially or completely without any intervening decidua is called :
Placenta accreta
Placenta increta
Placenta succenturiate
Placenta percreta
1b
multi
Placenta increta
Gynaecology & Obstetrics
null
ea4a7f36-fee1-4017-8909-eef7b0167758
What is the % Body surface area involved in burns of the perineum?
1%
3%
5%
9%
0a
single
Ans. (a) 1%Ref: Sabiston 19th ed. 1523Perineum involved in burns is 1% of body surface area.
Surgery
Initial Care of the Burn Patient
7a7d6f17-b955-4e3d-9cf5-883551961aed
Acute mechanical large bowel obstruction should be operated early because of the risk of -
Respiratory embarrassment due to abdominal distension
Electrolyte imbalance from vomiting
Septicaemia from bowel contents
Closed-loop obstruction and caecal perforation
3d
single
• Virtually all patients with complete acute large bowel obstruction require prompt surgical intervention and should not undergo a trial of non-operative management • Acute large bowel obstruction in patients with competent ileocecal valve is a true surgical emergency because of high chances of perforation (MC site: Ce...
Surgery
null
ff31cd05-0da1-4803-8126-32d2619368e1
Butcher&;s thigh is:
Vastus lateral rupture
Subcutaneous lipodermatosclerosis
Bursa in adductor canal
Accidental injury to major vessels in thigh or groin
3d
single
Butcher&;s Thigh: Butcher&;s thigh is penetrating wound of femoral triangle due to knife slipping while boning meat. Penetrating wound involving main veins in the thigh or groin are potentially fatal, as exangination may follow the first aid dressing which has apparently controlled the bleeding. Ref: Bailey 18th editio...
Surgery
Vascular surgery
b68498c2-5d89-4016-a288-cb60ec6b7df4
The gastrosplenic ligament is due to peritoneal reflection of which artery -
Splenic artery
Short gastric artery
Pancreatic artery
Common hepatic artery
1b
single
Ans. is 'b' i.e., Short gastric arteryPeritoneal ligamentsGastrosplenic ligament extends from hilum of spleen to greater curvature of the stomach. It contains short gastric and left gastroepiploic vessels. It develops from dorsal mesogastrium.Linorenal ligament extends from hilum of spleen to anterior surface of the le...
Unknown
null
43798c77-cd41-43d6-b44d-2a827833ff01
The drug of choice in Herpes Simplex Encephalitis is:
Acyclovir
Zidovudin
Amantadine
Vidarabine
0a
single
Answer is A (Acyclovir): The drug of choice in Herplex Simplex encephalitis is Acyclovir.
Medicine
null
bb303b19-b063-4cd0-a7db-08a8c0ec045b
Treatment of choice in Hodgkin's Lymphoma is:
CHOP
MOPP
ABVD
MOPP and ABVD hybrid
2c
single
Answer is C (ABVD) ABVD is the chemotherapy regimen of choice in Hodgkins lymphoma 'Chemotherapy with ABVD is considered the standard first line treatment for most patients and is superior to MOPP in efficacy and toxicity profile '- Manual of Clinical Oncology 6'"/443 Regimen Agents Comments ABVD Doxorubicin Bleomycin ...
Medicine
null
fddd9a1a-1058-40a5-ae91-3916a35e68a2
False positive urinary D-xylose test is seen in:
Ascites
Blind loop syndrome
Celiac disease
Eosinophilic gastroenteritis
0a
multi
An abnormal test (<4.5 g excretion) indicates the presence of duodenal/jejunal mucosal disease. Like celiac disease, crohn's disease, Eosinophilic gastroenteritis and small intestinal lymphoma. The D-xylose test can also be abnormal in blind loop syndrome. False-positive study is seen in patients with ascites and pleur...
Medicine
null
dc52fa7d-3b5c-4841-8085-ae68807d2f2f
All are features in Treacher-collin syndrome except:
Coloboma of inferior lid
Mandibular hypoplasia
Low intelligence
Cleft palate
2c
multi
Intelligence is not affected in Treacher-Collin syndrome(like Turners syndrome) Treacher-Collins syndrome/Franceschetti syndrome Autosomal dominant Facial appearance: downward sloping palpebral fissures, colobomas and drooping of the lower eyelids, sunken cheekbones, deformed pinnae, atypical hair growth extending towa...
Pediatrics
Genetic and genetic disorders
dfd9d5c8-7264-42a3-a510-9518db7a0f65
The heart lesion not found in Congenital Rubella infection is –
ASD
VSD
PDA
PS
0a
single
Cardiac anomalies in Congenital rubella (In decreasing order of frequency) → PDA (most common), PS, VSD, ASD ASD is the best answer amongst the given options because, amongst the given options, ASD is least commonly associated with congenital rubella.
Pediatrics
null
3473402d-fea6-45a0-8090-05baaf2d9b61
An 18 year old female patient complains of prominent upper front teeth. Extra-oral examination reveals an acute nasolabial angle and lip strain. Intraoral examination shows a Class II incisor relation with 8 mm overjet and Class I molar relation. Maxillary first premolar extractions have been advised, of which almost a...
Group A
Group B
Group C
Group D
0a
multi
It is convenient to classify an extraction arch by the differential space closure required between the anterior and the posterior teeth.  Group A arch is one in which posterior segments must remain in their original position and the full space is used for anterior retraction. Group B arch requires that approximately on...
Dental
null
d1ff13da-456f-44b2-b964-4d7f2b3ac049
permenant cerebellar damage is seen in lithium toxcity at what levels?
1-1.5 meq/l
>2 mew/l
>3 meq/l
>4meq/l
2c
single
ref : kd tripathi 8th ed
Pharmacology
All India exam
e7f37c60-8d14-489e-857f-adc9f77c4c4e
Bulls eye retinopathy is seen in toxicity of: (Repeat)
Chloroquine
Mefloquine
Primaquine
Quinine
0a
single
Ans A (Chloroquine) Ref: CMDT, 2013. pg 197Explanation:Adverse Effects of ChloroquineOcular- Irreversible retinal damage,CNS- Seizures. Tinnitus, Nerve deafnessGIT- Anorexia, nausea, vomitingSkin pigmentation
Medicine
Drugs
6e2ef67d-4d29-46c5-a08a-8ceae74ad149
Febrile response in CNS is mediated by?
Bacterial toxin
IL-1
IL-6
All
3d
multi
Ans. is 'a' i.e., Bacterial toxin; 'b' i.e., IL-1; 'c' i.e., IL-6 Pyrogenes Pyrogenes are substances that cause fever. Pyrogens may be exogenous or endogenous Exogenous --> Bacterial toxins Endogenous --> IL-1, TNF-a, IL-6, Interferons, Ciliory's neurotropic factor These pyrogenes increase the level of PGE2 in the hypo...
Pathology
null
38ab2687-72c5-48c2-8543-34e8a18279ef
Component of 50s subunit is/are:
23s
28s
25s
5.8s
0a
single
A i.e. 23s
Biochemistry
null
e120b642-3a7d-4d25-8c93-0f725b34574e
Which of the following muscle is derivative of 1st arch:
Stylopharyngeus
Tensor tympani
Platysma
Cricothyroid
1b
single
Tensor tympani muscle develops in the first pharyngeal arch. Stylopharyngeus develops in 3rd arch. Platysma develops in 2nd arch. Cricothyroid develops in 4th arch.
Anatomy
Pharyngeal Arches
0f052b33-e643-4a38-9e97-aa43ae8e7316
Chief judicial magistrate
District collector
Additional district magistrate
Sub collector
Any of the above
1b
multi
B i.e. Additional district magistrate
Forensic Medicine
null
1eaf3016-c749-432b-b7a7-2710eb2a338f
Which of the following is not a cestode?
Diphylobothrium latum
Taenia saginata
Schistosoma mansonia
Echinococcus granulosus
2c
multi
Ans. (c)(Ref: Parasitology-Protozoology and Helminthology by K.D. Chatterjee, 13th edition)Cestodes can be classified according to their habitat into:(a) Pseudophyllidean Cestodes: Possessing false or slit like grooves, include Dophyllobothrium latum (fish tapeworm), Sporganum mansoni, Sporganum proliferum.(b) Cyclophy...
Microbiology
Parasitology
ce0eea08-e732-4429-a9f4-557753ecd5d8
Pneumothorax in the new born can be treated by _____________
Oxygen
Surfactant
Trans illumination
Needle aspiration
3d
single
*Presence of air in the pleural cavity is most common in babies with meconium aspiration syndrome and those being ventilated* Transillumination can help in diagnosis *Needle aspiration or chest tube drainage is a life saving procedure in this situation . Reference : op Ghai pg 167 , 9 th edition
Pediatrics
New born infants
375f338b-2f13-4e98-a599-cd8ab4a30f28
The following antibiotic accentuates the neuromuscular blockade produced by pancuronium:
Streptomycin
Erythromycin
Penicillin G
Chloramphenicol
0a
single
* Aminoglycosides (like streptomycin and gentamicin) can accentuate the neuromuscular blockade produced by competitive blockers (like pancuronium). * Mechanism of neuromuscular blockade produced by aminoglycosides is the inhibition of presynaptic release of ACh.
Pharmacology
Antimicrobial Drugs