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135
41f3b32f-8774-4cf4-b076-d0dca81565ad
Chandler's index is associated with:
Hook worm
Pin worm
Roundworm
Guinea worm
0a
single
Ans. (a) HookwormRef : K. Park 23rd ed. / 243-44* CHANDLER'S INDEX is also known as Endemic index.* It is defined as average number of hookworm eggs per gram of stool for the entire community.* >300 eggs per gram of stool denotes important public health problem.Interpretation of chandler's index:Average No. of eggs/gm ...
Social & Preventive Medicine
Entomology
101db3a7-cb26-4529-b74f-77a36390d481
Gland derived from foramen caecum is
Thyroid
Parathyroid
Parathyroid
Parathyroid
0a
single
A. i.e. Thyroid
Anatomy
null
08031dc2-c299-4f8f-b43e-7e18f797605e
Korsakoff's psychosis is due to deficiency of: September 2003, March 2013 (b)
Vitamin B1
Vitamin B2
Vitamin B3
Vitamin B12
0a
single
Ans. A i.e. Vitamin B1
Social & Preventive Medicine
null
b5a9cf5a-ed2b-4a54-af39-b15b3b624bdc
What are the EEG waves recorded for the parietooccipital region with subject awake & eye closed
Alpha waves
Beta waves
Delta waves
Theta waves
0a
single
Alpha rhythm is most marked in parietal and occipital lobe. It is produced when the person is awake with eye closed.
Psychiatry
null
1572e11c-2a82-4278-956d-26e9078f9081
The awareness regarding the disease in psychiatric patient in mental status examination (MSE, not MSE was given in the question) is called:
Insight
Orientation
Judgment
Rappo
0a
multi
Answer- A. Insight InsightKnowledge of own disease/illness in mental status examinationInsightAwareness of own disease/illness in mental status examinationQOrientationComponent of cognitionQRappoPatien's attitudeQJudgmentPatients capacity to make sound decisinsQ
Psychiatry
null
0cfaac1e-d886-4df8-bb9f-5b5e4c4cb4f9
Which one of the following enzymes is not a protein, but an RNA molecule
Peptidyl transferase
RNA polymerse
Restriction endonuclease
Reverse transcriptase
0a
single
Some RNA molecules have intrinsic catalytic activity. The activity of these RNA enzymes, or ribozymes, often involves the cleavage of a nucleic acid. Two ribozymes are the peptidyl transferase that catalyzes peptide bond formation on the ribosome, and ribozymes involved in the RNA splicingRef: Harper 30th pg: 363
Biochemistry
Metabolism of protein and amino acid
324ed693-659a-42ed-9ab4-aec93e67cb1f
All of the following are approaches to health education, EXCEPT:
Service approach
Regulatory approach
Health education approach
Mass media
3d
multi
Mass media is a method of health communication. According to Alma-Ata declaration (1978), "Health education is a process aimed at encouraging people to want to be healthy to know how to stay healthy to do what they can individually and collectively to maintain health and seek help when needed". There are 4 well-known a...
Social & Preventive Medicine
null
433e13b5-2b35-42ed-bc25-392b50a37e44
Indirect ophthalmoscopy is done for:
Central retina
Periphery of retina
Sclera
Angle of ant. Chamber
1b
single
B i.e. Periphery of retina Indirect ophthalmoscopy is done for examination of periphery of retina upto ora serrata Q where as direct ophthalmoscopy can show slightly beyond equator.
Ophthalmology
null
ddf0d559-9f75-4c46-af70-9eb9e80211b5
Tests for detection of heavy metal:
Harrison's Gilroy test.
Atomic absorption spectroscopy
Neutron activation analysis
All
3d
multi
A i.e. Harrison Gilroy test; B i.e. Atomic absorption Spectroscopy; C i.e. Neutron activation analysis
Forensic Medicine
null
3d4107a8-b53c-413c-a9ea-225a15e289a0
All of the following are contents of middle mediastinum except
Phrenic nerve
Ascending aoa
Arch of aoa
Pulmonary aery
2c
multi
Arch of aoa occupies in the superior mediastinum B D CHAURASIA&;S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME 1 SIXTH EDITION Page no:246
Anatomy
Thorax
682b9795-5cd5-4464-9057-04c3f03a24ac
Which of the following is not a muscular suppo of uterus ?
pelvic diaphragm
pineal body
distal urethral sphincrer mechanism
round ligament of uterus
3d
single
Muscular or active suppos of uterus - 1. Pelvic diaphragm 2. Perinea! body 3. Urogenital diaphragm Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 2 ,pg.no., 423.
Anatomy
Abdomen and pelvis
bf0dbdb9-f0ba-4c00-960c-8f7a58d78765
A female wanted to have an emergency contraception after an unprotected intercourse. Which of these is NOT useful as an emergency contraceptive?
LNG IUD
Oral Mifepristone
Oral Levonorgestrel
Cu-containing IUD
0a
single
Post coital or emergency contraceptives are, Ethinyl oestradiol Conjugated estrogen Ethinyl oestradiol + Norgestrel Levonorgestrel Mifepristone Copper IUDs Ref: Textbook of Obstetrics by D.C. Dutta, 6th edition, Page 550.
Gynaecology & Obstetrics
null
0c21cd77-685b-43fd-9df4-de60759373ef
Episcleritis is commonly associated with: March 2012
Trachoma
Rheumatoid ahritis
Cataract extraction surgery
Usually associated with none
1b
multi
Ans: B i.e. Rheumatoid ahritis Scleritis & associations A history of rheumatoid ahritis is commonly obtained in patients with episcleritis Cataract extraction surgeries may be associated with scleritis Posterior scleritis is usually not associated with any systemic disease
Ophthalmology
null
e465aa8b-44b0-4aed-89b6-f1747e63adea
Hemoglobin is present in :
Hydrophilic pockets
Hydrophobic pockets
Pyrrole rings
Cationic ring
1b
single
Hemoglobin, a tetrameric protein of erythrocytes, transpos O2 to the tissues and returns CO2 and protons to the lungs. The heme in haemoglobin is surrounded by a hydrophobic pocket, which is necessary in order for it to bind oxygen reversibly without undergoing oxidation or other undesirable reactions. Ref: Kennelly P....
Biochemistry
null
122e7f6d-46a9-44b4-be04-ed10f7f551c1
Gas gangrene is caused by:
Clostridium botulium
Clostridium perfringens
Clostridium difficile
Clostridium tetani
1b
single
Ans: B (Clostridium perfringens) Ref: Ananthnarayan R, Paniker CKJ. Textbook of Microbiology. 8th Edition. Hyderabad: Universities Press; 2(X)9. Pg. 251Explanation:Gas gangreneCaused byCl. perfringensCl. septic uniCl. odematieunsCl. sporogenesCl histolyticum (Aerotolerant anaerobe)Virulence factorsExotoxins - hemolytic...
Microbiology
Clostridium
278d33be-6e60-4ce1-a65d-2898d1bd46ef
Immunoflorescence pattern in pemphigus vulgaris is suggestive of ?
Intercellular IgG deposition
C3 and IgG deposition at dermo-epidermal junction
IgA deposition at dermo-epidermal junction
IgA at pappilary tip
0a
single
Ans. is 'a' i.e., Intercellular IgG deposition
Skin
null
f9e4b064-b7bb-4b11-b74a-66a7782cef67
OCP should not be used with
Rifampicin
1NH
Streptomycin
Pyrazinamide
0a
single
Rifatnpicin See Nov 09 Obs & Gynae
Pharmacology
null
00241d46-b148-46e5-bc81-7a9db64bf087
At the end of 5th week of gestation, how many numbers of somites can be seen?
24
26
38
44
3d
single
The first pair of somites arises in the occipital region of the embryo at approximately the 20th day of development, from here new somites appear in craniocaudal sequence at a rate of approximately three pairs per day until at the end of the fifth week 42 to 44 pairs are present Ref: Gray's 39e/p-210-220
Anatomy
General anatomy
5d3adac4-68bb-4a6c-870d-a6ebe753ae09
40 yr old woman presents to your clinic with complaints of headache and dizziness. She has an infection of a cranial dural sinus; one that lies in margin of the tentorium cerebelli and runs from the posterior end of cavernous sinus to transverse sinus is infected. Which of the following sinuses is affected by inflammat...
Superior petrosal sinuses
Inferior sagittal sinus
Sphenoparietal sinus
Straight sinuses
0a
single
Superior petrosal sinus runs from cavernous sinus to transverse sinus along attached margin of the tentorium cerebelli. This patient has meningitis (inflammation of the meninges), which causes headache and dizziness. Straight sinus runs along line of attachment of falx cerebri to tentorium cerebelli. Inferior sagittal ...
Anatomy
Brainstem lesions and blood supply of CNS
335056bb-f185-4686-87b0-19c3d2dd7f60
Compound microscope was invented by: September 2004
Louis Pasteur
Hippocrates
Robe Hooke
Leeuwenhoek
2c
single
Ans. C i.e. Robe Hook
Microbiology
null
1c64d025-4518-4df6-b18a-50b60d02e1a7
Radiorestistant tumor is-
Ewings sarcoma
Retinoblastoma
Osteosarcoma
Neuroblastoma
2c
single
RADIORESISTANT RADIOSENSITIVE Osteosarcoma Wilms tumor Melanoma Ewing's sarcoma Hepatic carcinoma Lymphoma Pancreatic carcinoma Myeloma Seminoma / Dysgerminoma
Radiology
Radiotherapy Pa 2
86ba813b-309c-4a28-9d67-d63a0cfd267b
All of the following are true regarding Legionella except.
Legionella can be grown on complex media
L. pneumophila serogroup 1 is the most common serogroup isolated from humans
Legionella are communicable from infected patients to others
L. pneumophila is not effectively killed by polymorphonuclear leukocyte
2c
multi
Ans. is 'c' i.e., Legionella are communicable from infected patients to othersRef: Harrison, 19th/e, p. 1014; Ananthanarayan, 9th/e, p. 401* No man to man transmission occurs.* Aspiration is predominant mode of transmission. Other modes include aerosolization, direct instillation into lungs.* Aerosolization by AC, nebu...
Microbiology
Bacteria
9d0edc66-384c-4482-8eef-761691c84770
Musculo skeletal abnormality in neurofibromatosis is
Hyperophy of limb
Scoliosis
Cafe au lait spots
All
3d
multi
Ans. is `d' i.e., All
Surgery
null
441dfb2d-9404-42f3-bb40-3e4df579899c
Safest treatment for hyperthyroidism in pregnant women is
Radioactive iodine
Methimazole
Carbimazole
Propylthiouracil
3d
single
Ans. d (Propylthiouracil). (Ref. Harrison, Internal Medicine, 18th ed.,/Chapter 40., KD Tripath 5th/232)Propylthiouracil:# During pregnancy thyroidectomy and I131 are contraindicated. With anti-thyroid drugs risk of foetal hypothyroidism and goiter are there.# However, low doses of propylthiouracil are preferred as it ...
Pharmacology
Endocrinology
f2e975a1-2a59-46ec-96cd-54b066f43dfa
Malaria predominantly cause which type of nephrotic syndrome
MPGN
Membranous
FSGS
Minimal change disease
0a
single
MPGN > Membranous  > FSGS.
Medicine
null
41dae4a5-639a-4bb2-93c6-1b8f5fed4ad2
Imipenem is combined with cilastatin to:
Cilastatin prevents degradation of imipenem in kidney
Cilastatin inreases intestinal absorption of imipenem
Cilastatin inhibits beta lactamase activity
Both have synergistic activity against Pseudomonas
0a
multi
Ans. (A) Cilastatin prevents degradation of imipenem in kidney(Ref: Goodman and Gilman 13th/e p1035)Imipenem is rapidly inactivated by renal dehydropeptidase I, so it is combined with cilastatin, an inhibitor of this enzyme.Cilastatin increases the half life of imipenem and also inhibits the formation of nephrotoxic me...
Pharmacology
Anti Microbial
d0bf5870-1e0f-4426-8cc5-32a89b112aa3
Fibrates - false is
They increase lipoprotein lipase activity through PPAR alpha, and cause increased lipolysis of triglycerides.
They are better absorbed when taken on empty stomach, than when taken with food
Cause utricaria, rashes, alopecia, myopathy and G.I. distress.
Are first lines of drugs in severe dysbetalipoproteinemias and hypertriglyceridemias.
1b
multi
Ans. is 'b' i.e. They are better absorbed when taken on empty stomach, than when taken with food Fibric acid derivations (Fibrates)The class includes:-BezafibrateCiprofibrateFenofibrate andGemfibrozil * The original fibrate clofibrate is obsolete.Mechanism of action:These drugs act by activating lipoprotein lipase whic...
Pharmacology
Hypolipidemic
3325652c-4e92-4eba-844f-191f45b5ff89
Vasodilator Nitric oxide is derived from which of the following:
Proline
Histidine
Arginine
Lysine
2c
single
Derivatives of amino acids Proline is conveed to glutamate (by a series of steps) and then transaminated to alpha-ketoglutarate Histidine on decarboxylation, gives the corresponding amine i.e. histamine Arginine is the substrate for the production of nitric oxide (NO)
Biochemistry
null
b930aa21-451b-4705-b27e-5b4b376cd98e
A 30 year old pregnant woman presents to a physician with painful oral ulcers. Physical examination demonstrates widespread erosions of her mucous membranes. Close examination reveals a friable mucosa, but no well-defined aphthous ulcers. Biopsy of perilesional mucosa demonstrates acantholysis; direct immunofluorescenc...
Bullous pemphigoid
Dermatitis herpetiformis
Herpes simplex I
Pemphigus vulgaris
3d
single
This is pemphigus vulgaris, in which autoantibody directed against transmembrane cadherin adhesion molecules induced acantholysis (breakdown of epithelial cell-cell connections) with resulting intraepidermal blister formation. It may develop spontaneously or following triggers such as drugs (thiols, penicillamine), phy...
Skin
null
f2e747db-0a59-4167-a20d-98460d64da6f
Trichomoniasis is transmitted through which stage
Cyst
Oocyst
Sporozoite
Trophozoite
3d
single
Trichomonas vaginalis exists only as a trophozoite; no cyst stage has been identified.
Pathology
All India exam
921271cc-ca0c-4433-a911-86dade7e87b7
Which receptors are blocked in Myasthenia Gravis?
Ach receptor
Ca++ receptors
Na+ receptors
Opioid receptors
0a
single
Auto-antibodies destroy some of the Nicotinic acetylcholine receptors and bind others to neighbouring receptors, triggering their removal by endocytosis.
Physiology
Muscle
cc5f34cb-6a37-4dcb-907b-309673413268
All of the following drugs are protease inhibitors EXCEPT:
Nelfinavir
Saquinavir
Abacavir
Ritonavir
2c
multi
ANTIVIRAL DRUGS: CLASSI FICATION 1.Anti-Herpes virus Idoxuridine, Acyclovir, Valacyclovir, Famciclovir, Ganciclovir*, Foscarnet* 2 Anti-Retrovirus (a) Nucleoside reverse transcriptase inhibitors (Nis): Zidovudine (AZT), Didanosine, Zalcitabine*, Stavudine, Lamivudine, Abacavir (b) Nonnucleoside reverse transcriptase in...
Pharmacology
Chemotherapy
d0116f68-3482-4d3a-9895-06b001ece9b8
In which leukemia, autoimmune hemolytic anemia is most common: -
ALL
AML
CML
CLL
3d
multi
CLL is the most common of the known cause of AIHA
Medicine
Sickle Cell Disease, G6PD deficiency and other Hemolytic Anemia
23fee466-da90-455c-89ad-fef2b0613241
A patient on amiodarone is diagnosed to have cornea verticillata. What should be management: (PGI Dec 2010)
Stop the drug
Penetrating keratoplasty
Lamellar keratoplasty
Observation
0a
single
Ans: A (Stop the drug) {Ref: Parson 20th/ 206 ; American Academy of Ophthalmologist: Cornea Section 8 2009-2010/375;Cornea by Krachner 2nd/365-69; Kanski 6th/321]Cornea Verticillata Parson 20th/206This is a whorl- like opacity in the corneal epithelium seen in patients on long-term treatment with medication such ad ami...
Ophthalmology
Cornea
6cddeb8d-1614-4658-8a07-124bb9efd1b4
\r\nA few months after receiving an IM injection a ladypresented to you with pain in both the shoulders. On examination there is sensory loss over bilateral shoulders with mild wasting of muscles. Which of the following vaccines is the likely cause?
Tetanus
Measles
MMR
BCG
0a
multi
This is a case of brachial neuritis following an injection of tetanus toxoid. Here there is dysfunction of the nerves supplying the arm or shoulder without involvement of the rest of the nervous system. The sensory loss is less prominent than the weakness. There may also be bilateral involvement of muscles with wasting...
Social & Preventive Medicine
null
d8a8fe00-ffd0-43e3-bb5b-bd84a324d9b4
What is the indication for surgery in asymptomatic patients with abdominal aortic aneurysm?
Transverse diameter > 3 cm
Transverse diameter > 5.5 cm
Transverse diameter > 7.5 cm
No need for surgery unless symptomatic
1b
single
Most precise test for imaging aortic aneurysm : CT scan 5-year risk of rupture for aneurysm :<5cm – 1 to 2% and > 5 cm-20 to 40% For asymptomatic abdominal aortic aneurysms, operation is indicated if the diameter is > 5.5 cm In elective surgery of AAA, the operative mortality rate is 1 to 2% whereas after acute rupture...
Unknown
null
57d40e41-4597-4cf6-8b13-ab250caadf2f
Which of the following is a polyunsaturated fatty acid?
Palmitic acid
Stearic acid
Oleic acid
Linoleic acid
3d
single
Three polyunsaturated fatty acids, linoleic acid, linolenic acid and arachidonic acid are called "essential fatty acids" (EFA). They cannot be synthesised in the body and must be provided in the diet. Lack of EFA in the diet can produce growth retardation and other deficiency manifestation symptoms.Ref: Textbook of Med...
Biochemistry
Metabolism of lipid
0fae0ed8-dc6e-401d-84fb-53461ea061cd
The child , Pretends in play at the age of __________
18 months
24 months
30 months
36 months
2c
single
Emerging patterns of social behaviour from 1-5years of age 15months Indicates some desires or needs by pointing Hugs parents 18months Feeds self Seeks help when in trouble May complain when wet or soiled Kisses parent with pucker 24months Handles spoon well Often tells about immediate experiences Helps to undress Liste...
Pediatrics
Growth and development
6ad4c162-d50f-4be4-84ae-d5aa59d50507
Chemically, oestrogens are characterised by
Absence of O2 at D-17
Aromatic character at D-ring
Absence to methyl group at C-10
A 21-carbon steroid skeleton
2c
multi
One hydroxyl group attached to the D ring
Biochemistry
Endocrinology
e4498791-b38f-49c4-b7bf-3287bdd4ab47
A 60 yr old lady presented with mild hearing loss & pulsatile tinnitus of right ear. Otoscopy revealed following findings. Most probable diagnosis is
Acoustic neuroma
Glomus tumor
Squamous cell carcinoma
Aural Polyp
1b
single
FINDINGS OF GLOMUS TUMOR: Otoscopy shows a red reflex through intact tympanic membrane. "Rising sun" appearance is seen when tumour arises from the floor of middle ear. Sometimes,tympanic membrane appears bluish and may be bulging. "Pulsation sign" (Brown sign) is positive, i.e. when ear canal pressure is raised with S...
ENT
Glomus
3cded425-19e1-4c4d-9ad8-5d17c87a23c5
which of these is a charecterstic of type A personality
competitive
dependent
suspisous
odd and excentric
0a
single
there are two types of personality disorders TYPE A PERONALITY PEOPLE are called' BORN WARRIORS' who are workaholics end up having hea disease TYPE D PERSONALITY PEOPLE are called 'BORN WORRIERS' who ruminate and have high risk of hea disease Ref. kaplon and Sadock synopsis of psychiatry, 11 th edition, pg no.746
Psychiatry
Personality disorders
420685e6-26ed-4c31-99b9-099f1a5e6f0f
Polychromatic lustre is seen in –
Complicated cataract
Diabetes mellitus
Post radiation cataract
Congenital cataract
0a
single
The earliest finding of complicated cataract is a polychromatic luster at the posterior pole of lens.
Ophthalmology
null
f7636d66-0877-44f8-aa99-72c1fb13ea5f
The most common benign tumor of the lung is
Hamaoma
Alveolar adenoma
Teratoma
Fibroma
0a
single
The most common benign lung tumor is a hamaoma,a developmental abnormality containing mesothelial & endothelial elements.Diagnosis is achieved by excision of the lesion. Reference:Bailey & Love's sho practise of surgery,25th edition,page no:891
Surgery
Cardio thoracic surgery
6b66ea92-4036-4287-84c9-e551c1a6ff2f
Dose limiting toxicity of amphotericin B is
Infusion related reaction
Renal tubular acidosis
Myelosuppression
Hypotension
1b
single
Ref-KDT 6/e p759 Amphotericin B can Cause: Dose limiting nephrotoxicity (A) Infusion related reactions (not dose related) Hypokalemia Hypomagnesenia
Anatomy
Other topics and Adverse effects
8b861ea3-001c-4fec-b45d-b32c0ba10966
Enzyme that produces single strand nicks in DNA:
DNA polymerase I
DNAase I
Polynucleotide kinase
l - exonuclease
1b
single
Deoxyribonuclease I (DNAase I) Acts on single-stranded DNA, double-stranded DNA, and chromatin. Makes single stranded cuts in nearly any segment of DNA i.e. has low sequence specificity. Digest DNA that is not protected/not bound by protein, into its component deoxynucleotides. Used in DNA Foot Printing. E.g. (DNase I)...
Biochemistry
Replication
3d3aa176-a815-488c-8753-cd68771eca05
Regarding IMNCI, when should refer the clild to higher centre?
Pneumonia
Severe pneumonia
Persistent diarrhea
All of above
1b
multi
Ans. is 'b' i.e., Severe pneumonia Refer urgently to hospital afte giving instruction in following cases :? Possible serious bacterial infection Severe jaundice Diarrhoea with severe dehydration Severe persistent diarrhoea (not PERSISTENT DIARRHOEA) Severe dysentry Not able to feed or severe malnutritions Severe pnumon...
Pediatrics
null
25d51302-993c-4302-92d0-4635a7433f4c
In gene cloning, largest fragment can be incorporated in:
Plasmid
Bacteriophage
Cosmid
Retrovirus
2c
single
C i.e. Cosmid
Medicine
null
dca4536e-8c8a-4034-b35a-e0e98d4ec806
Injury to head of fibula may involve following except:
Anterior tibial nerve
Common peroneal nerve
Tibial nerve
Superficial peroneal nerve
2c
multi
C i.e. Tibial nerve
Anatomy
null
384e7abe-73b4-43cd-93d9-d37f1c958821
Remnants of WolFion ducts in a female are in
Pouch of Douglas
Broad ligament
Utero vesical pouch
iliac fossa
1b
single
Ganer&;s duct remnants of mesonephric duct in female Located in Broad ligament ref : BD CHAURASIA
Gynaecology & Obstetrics
All India exam
efc0cd46-ebec-43d8-bed7-a376cfb46211
All of the following nerves are involved in the process of erection of penis, EXCEPT:
Pudendal nerve
Sacral plexus
Hypogastric plexus
Nervi erigentes (S2,3,4)
2c
multi
Erection is parasympathetic and emission and ejaculation are parasympathetic. The erectile response is mediated by a combination of central (psychogenic) innervation and peripheral (reflexogenic) innervation. Sensory nerves that originate from receptors in the penile skin and glans converge to form the dorsal nerve of ...
Anatomy
null
1d884666-dad3-45dd-9868-d658737bd2ee
Rotation of a distal extension base around longitudinal axis is resisted by
Rigidity of major connector
Rigidity of minor connector
Both of the above
None of the above
2c
multi
A second movement is rotation about a longitudinal axis as the distal extension base moves in a rotary direction about the residual ridge. This movement is resisted primarily by the rigidity of the major and minor connectors and their ability to resist torque.
Dental
null
e1565d0f-8ed7-4b17-803f-c81c59960fc1
Microalbuminuria is defined as-
0.3-0.5 g of 24 hours urine protein
0.03-0.3 g of 24 hours protein
0.03-0.3 g of 24 hours urine albumin
> 2.5 g of 24 hours urine protein
2c
single
Ref:Harrison 20th edition pg no. 2134 Albumin is detected by radioimmunoassay. Albumin /creatinine (mg/g) 24h urine protein (mg/24h) 24 hr albumin(mg/24h) Normal <30 <150 8-10 Microalbuminiuria 30-300 - 30-300 Proteinuria >300 >150 >300 Ref Harrison20th edition pg 267
Medicine
Kidney
c5d3db1f-05c4-44a8-8c2f-2c25ef28c376
Commonest histological type of rhabdomyosarcoma of orbit is
Embryonal type
Alveolar type
Pleomorphic type
None of the above
0a
multi
Embryonal RMS Occurs in children < 10 years of age. Chr IIP involved.
Ophthalmology
null
897a1148-d962-4d5b-8926-4abe38ad5108
All are true of Hodgkins lymphoma except ?
Bimodal age pattern
Females less common
Contiguous spread
Osteolytic metastasis
3d
multi
Ans. is 'd' i.e., Osteolytic metastasis
Pathology
null
1c5eadca-e9c4-4840-9e98-ae0f539ea1d7
Which of the following immunosuppressants is not used for the treatment of cancers?
Cyclophosphamide
Cyclosporine
Methotrexate
6-Mercaptopurine
1b
single
(Ref: KDT 6/e p839, 840) All antimetabolites can be used as anticancer drugs except azathioprine. Cyclosporine acts by inhibiting the transcription of IL-2 gene. It has no anti-cancer propey.
Pharmacology
Other topics and Adverse effects
27ce39d3-c8e9-407d-8689-3569228fe50a
Carotid artery stenosis screening invivo choice is :
USG
CT
MRI
Doppler
3d
single
Color doppler ultrasonography is the screening method of choice (not simple USG : option a is incorrect). Carotid angiography is the investigation of choice for diagnosis.
Radiology
null
0a39d455-53a0-4b21-8e5e-4915dda8f362
H5N1 is strain of -
An flu
New vaccine againts AIDS
Aent for japanese encephalitis
Causes chickengunya fever
0a
single
H5N1 is the strain of an influenza REF:<\p> MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.502
Microbiology
Virology
1a31abe7-fbc1-41bc-b42d-fab66edfef39
The most important career of cholesterol in plasma is:
VLDL
LDL
HDL
Chylomicrons
1b
single
Transport of Cholesterol between tissues: Dietary cholesterol is incorporated into Chylomicrons. 95% of Chylomicron cholesterol is delivered to liver in Chylomicron remnant. The cholesterol is secreted from liver in VLDL. Most of the cholesterol secreted in VLDL is retained in IDL and ultimately LDL. LDL cholesterol i...
Biochemistry
null
afa2e25c-1602-4a23-8a0b-9e384e07b0a4
Which of the following drug is effective against HIV with Y181C mutation?
Festinavir
Lersivirine
Elvitegravir
Dolutegravir
1b
single
Festinavir is an NI shown to be effective in adefovir and tenofovir resistanceLersivirine is an NNI effective against HIV with Y181C mutationElvitegravir is an integrase inhibitor used for initial / naive treatmentDolutegravir is an integrase inhibitor approved for raltegravir-resistant infections
Microbiology
All India exam
69131403-2d23-4a5e-a758-9168ebdbb802
pH is 7.2; PCO2 12; PO2 55 most likely cause is -
Metabolic acidosis and respiratory alkalosis
Metabolic alkalosis
Respiratory acidosis
Respiratory alkalosis
0a
single
In this patient pH → Decreased (Normal 7.4) PCO2 → Decreased. First step Determine whether it is acidosis or alkalosis. The decrease in pH suggests acidosis. Second step Observed HCO3-/PCO2 to determine the cause of acidosis or alkalosis Only one value is mentioned and that too is not in sync with the pH PCO2 value ...
Medicine
null
e2d239bb-a31c-4a2b-8d52-2e577d0b54b4
A 14-year-old girl is rushed to the emergency room after receiving a gunshot wound to the head and is pronounced dead on arrival. If this child died due to an immediate "blast effect" of the penetrating wound, the autopsy would likely show herniation of the tonsils of the cerebellum into which anatomic space?
Aqueduct of Sylvius
Central spinal canal
Foramen magnum
Foramen of Magendie
2c
single
Penetrating wounds produce hemorrhage and blast effects. The "blast effect" of a high-velocity projectile causes an immediate increase in supratentorial pressure and results in death because of impaction of the cerebellum and medulla into the foramen magnum. A low-velocity projectile increases the pressure at a more gr...
Pathology
Central Nervous System
b61f14f1-48f2-4826-aa76-3642841b325f
All are seen in non-proliferative diabetic retinopathy except -
Microaneurysm
Neovascularization
Hard exudates
Macular edema
1b
multi
Ans. is 'b' i.e., NeovascularizationClassification of Diabetic retinopathyNonproliferativeProliferativeBackground retinopathyo Microaneurysmo Dot and blot hemorrhage (deep hemorrhage)o Hard exudateo Macular edemaPreproliferative retinopathyo Cotton-wool spots (soft exudates)o Venous beadingo Extensive hemorrhageo Intra...
Ophthalmology
Vascular Disorders
097d80fe-0ee8-4b11-8791-67be51722c4a
Van Nuys grading is used for
LCIS
DCIS
Medullary carcinoma breast
Inflammatory breast cancer
1b
single
Van Nuy's prognostic index score(VNPI) is used for Ductal Carcinoma In Situ. For calculating VNPI score we consider Size in mm, Clearance margin in mm, Grade and necrosis, Age in years and each has score according to a definite criteria. All the scores are added together. 1)If points are 4-6 = % of local recurrence is ...
Surgery
Endocrinology and breast
55fa61da-b15a-419c-a2a4-a65752ec51b8
In which of the following conditions Berlin's edema is seen -
Open angle glaucoma
After cataract surgery
After concussional trauma
Diabetic retinopathy
2c
single
Berlin's oedema, also called comnzotio retinae, occurs in blunt trauma to eye. It manifests as milky white cloudiness involving a considerable area of the posterior pole with a 'cherry-red' spot in the foveal region.
Ophthalmology
null
ed99fb90-b73c-4eea-885a-aa5eab7ad188
Genomic imprinting is seen in-
Prader willi syndrome
Marfan syndrome
EDS
Osteogenesis imperfecta
0a
single
Ans. is 'a' i.e., Prader willi syndrome
Pathology
null
d649f3a9-d472-48bd-9dae-47ed0f30327b
Punishment for Rape is under which section of IPC -
375
376
312A
304A
1b
single
Ref: Textbook of forensic medicine and toxicology (V.V.Pillay)17th edition page no.389 The punishment for rape is prescribed in sec.376IPC with two subsection. Subsection 1:for rape described in Sec.375IPC imprisonment for at least seven years and liability to fine,unless victim is his own wife and is not less than twe...
Forensic Medicine
Sexual offences and infanticide
179e3ce2-bcd3-4e52-a872-b6aae5d82402
Which of the following nerve is most commonly damaged during wrist slash injury?
Ulnar nerve
Radial nerve
Median nerve - palmar cutaneous branch
Median nerve
3d
single
The median nerve lies very superficially at the wrist, in the interval between the tendons of the flexor digitorum superficialis and the flexor carpi radialis muscles just proximal to its entry under the flexor retinaculum in the hand. During wrist slash injuries, the other nerve which could be damaged is ulnar nerve, ...
Physiology
All India exam
bfe880a8-c35e-4926-b0c3-fc6724d298d4
Mastitis in infants ?
Treated with antibiotics
More common in boys
It is a congenital infection
Most common organism is E Coli
0a
single
Ans. is 'a' i.e., Treated with antibioticsMastitis (infection of breast tissue) typically occurs in infants after 2 months of age. During the first 2 weeks of life, it occurs with equal frequency in males and females; thereafter, it is more common in girls, with a female:male ratio of approximately 2:1.The majority of ...
Pediatrics
null
04011be2-ee71-4658-905f-5dcc287076cc
Multiple painful bleeding ulcers with inguinal bubo is seen with
Chancre
Granuloma inguinale
Lymphogranuloma Venerum
Chancroid
3d
single
Ans. (D) Chancroid
Skin
S.T.D.
8eea2fd5-ebd1-421c-a8c9-a9827cb742cd
Substrate for ATP synth ase is -
AMP
ADP
IMP
GMP
1b
single
Ans. is 'b' i.e., ADP o ATP synthesis occurs in ETC by enzyme F0F1, ATPase.o F1. component of F0F1, ATPase is ATPase synthase which catalyzes the conversion of ADP to ATP.ATP synthesis in ETCo Free energy of electron transport" is conserved by pumping protons from mitochondrial matrix to the intermembrane space, so as ...
Biochemistry
Respiratory Chain
d6c5d3cc-488d-4008-be99-9b04ff8721b2
Laudanosine is metabolite of which of the following?
Cisatracurium
Atracurium
Pancuronium
Gallamine
1b
multi
Laudanosine is a principal metabolite of atracurium, it has no neuromuscular blocking effects. Laudanosine freely crosses the blood brain barrier and in high concentration act as a CNS stimulant. It is primarily cleared through the liver.
Anaesthesia
null
55b6919a-2971-461a-898a-731a40d807eb
Lateral wall of middle ear is formed by:
Tegmen tympani
Mastoid process
Promontory
Tympanic membrane
3d
multi
Roof - Thin plate called as tegmen tympaniFloor - Jugular bulbAnterior wall - Internal carotid aeryPosterior wall - Lies close to mastoid air cellsMedial wall - labyrinthLateral wall - tympanic membrane
ENT
null
2763442a-549e-4778-8fcb-a02dab07fcbe
The structure not passing through the aoic opening of the diaphragm is
Aoa
Azygous vein
Thoracic duct
Vagal trunk
3d
single
The vagal trunk does not pass through the aoic opening of the diaphragm. It passes through the esophageal opening at the level of T10 veebrae. Major openings through the diaphragm Level of opening T8 T10 T12 Located in In the central tendon In the muscular pa In the crus of the diaphragm Structures passing through Infe...
Anatomy
All India exam
f7979a38-a308-4bb3-bbc7-56463f9f5ed8
QT prolongation is seen in all, except:
Hypothermia
Digitalis toxicity
Hypocalcemia
Romanowand syndrome
1b
multi
Answer is B (Digitalis toxity) QT interval is shoened in digitalis toxity and not prolonged QT interval Is measured from the beginning of Q wave to the end of T wave Q It is the time taken for total ventricular events i.e. depolarization as well as repolarization 2 Normal QT interval should not exceed 42 seconds
Medicine
null
a500f4f6-97e2-4fee-b629-665677e03a7f
All of the following are examples of traction epiphysis, EXCEPT:
Mastoid process
Condyles of tibia
Trochanter of femur
Tubercles of humerus
1b
multi
Traction epiphysis is caused by the pull of muscles. Greater and lesser trochanter of femur, greater and lesser tubercle of humerus, medial and lateral epicondyles of humerus and mastoid process are all examples of traction epiphysis. Condyles of tibia is a type of pressure epiphysis.
Anatomy
null
44513c21-0423-43cf-8123-6700fb3da530
The histology of pterygium includes -
Elastotic degeneration
Epithelial inclusion bodies
Precancerous changes
d) Squamous metaplasia of the epithelium
0a
single
Pathologically pterygium is a degenerative and hyperplastic condition of conjunctiva. The subconjunctival tissue undergoes elastotic degeneration and proliferates as vascularised granulation tissue under the epithelium, which ultimately encroaches the cornea. The corneal epithelium, Bowman&;s layer and superficial stro...
Ophthalmology
Conjunctiva
1d47fd65-e736-4659-8b67-827cb3b1d188
Following are radiological features of scurvy except?
Bony thickening
Metaphyseal widening
Metaphyseal calcification
Epiphyseal separation
1b
multi
Ans. is 'b' i.e., Metaphyseal wideningRadiological features of scurvyo The typical radiological features occur at the ends of long bones, paicularly around knee, i.e. lower end offemur and upper end of tibia. Other common site is proximal end of humerus.o Features are -Ground glass appearace of bone Pencil thin coex Wh...
Pediatrics
null
74a0cdfc-84df-4efe-9b6e-08e7ba34805c
Position of the patient should be as described except:
Diagnostic laparoscopy - Trendelenburg with about 30° tilt
Colposcopy -Lithotomy
Transvaginal sonography in gynecology - Lithotomy with full bladder
Hysteroscopy - Lithotomy
2c
multi
As the position described in the question are correct with respect to the surgery except for TVS. In TVS, the position is dorsal with legs drawn up and not lithotomy Full bladder may or may not be required.
Gynaecology & Obstetrics
null
a221e59f-7928-47a1-a4f9-dca9bef9fcbe
Granulation tissue comprises of:
Fibroblasts
Small blood vessels
Macrophages
All of the above
3d
multi
The combination of proliferating fibroblasts, loose connective tissue, new blood vessels and scattered chronic inflammatory cells, forms a type of tissue that is unique to healing wounds and is called granulation tissue. This term derives from its pink, soft, granular gross appearance, such as that seen beneath the sca...
Pathology
null
b53c338c-ee25-4e1e-a179-2128253d1803
In which one of the following conditions is gas under diaphragm not seen
Perforated duodenal ulcer
Typhoid perforation
After laparotomy
Spontaneous rupture of oesophagus
3d
single
After spontaneous rupture, the pressure in the oesophagus rapidly increases and burst at its weakest point in lower one-third, sending a stream of material into the mediastinum and often into the pleural cavity. Thus pneumomediastinum is formed Reference: Bailey and Love edition: 24 page no: 996
Surgery
G.I.T
f3736dea-8098-4c26-a901-bb5ff68e569c
Protein requirement in adult male -
0-5 gm/kg/day
1 gm/kg/day
1-5 gm/kg/day
2 gm/kg/day
1b
single
Ans. is 'b' i.e., I gm/kg/day Recommended protein allowancesGroupParticulars(g / kg / day)Man(60 kg)sedentaty workmoderate workheavy work1Woman(55 kg)sedentary workmoderate workheavy work1Infants0 to 3 months3 to 6 months6 to 9 months9 to 12 months1.161.161.691.69Children1 to 3 years4 to 6 years7 to 9 years1.31.121.18A...
Social & Preventive Medicine
Proteins
7eb616c5-dcf0-4997-9599-9fed0e352c2e
Which first line antitubercular drug is bacteriostatic ?
INH
Rifampicin
Ethambutol
Pyrazinamide
2c
single
Ans. is 'c' i.e., Ethambutol o All first line drugs are tuberculocidal except ethambutol which is tuberculostatic.Thberculocidal -Rifampin, INH, streptomycin, pyrazinamide.Tuberculostatic - Ethambutol, PAS, cycloserine, thioacetazone.
Pharmacology
Anti Microbial
260bf6a4-e5ff-466a-bd6a-e6c58e32ff24
Febuxostat is indicated in the treatment of:
Hyperkalemia
Hyperuricemia
Hypernatremia
Hypercalcemia
1b
single
Febuxostat is a non purine inhibitor of xanthine oxidase which is required for oxidation of hypoxanthine and xanthine to uric acid. It is usually used in gout especially in patients who are intolerant to allopurinol. Other drugs used in the treatment of hyperuricemia: Uricosuric drugs Probenecid Sulfinpyrazone Uric aci...
Pharmacology
null
2e35953c-9529-4a68-9899-e012edf857e4
Eosinophilia in necrosed tissue is due to ?
Coagulation of proteins
Denaturation of enzymes
Denaturation of protein
Mitochondrial damage
2c
single
Necrotic cells show increased eosinophilia in hematoxylin and eosin (H & E) stains. It is mainly due to these 2 Factors Loss of cytoplasmic RNA (or ribonucleoprotein/RNP) which binds the blue dye, hematoxylin. Denatured cytoplasmic proteins which bind the red dye, eosin.
Pathology
null
29cfb54c-33a2-4b0b-a14c-1726303dc1c3
Irreversible cell injury
Mitochondrial densities
Cellular swelling
Blebs
None
0a
multi
In irreversible cell injury, there are deposits of amorphous calcium salts in the mitochondrial matrix.(REF: Textbook of Pathology HARSH MOHAN 6th Edition page no.30)
Physiology
General physiology
59b80ae5-50c6-48fc-ba45-edd6730a3f5c
Mite is a vector for -
R.typhi
R.prowazeki
R.rickettsii
R.tsutsugamushi
3d
single
Mite transmits: Rickettsial Pox and Scrub Typhus Agent for Rickettsial Pox: R.akari Agent for Scrub Typhus: Orientia tsutsugamushi (old name- R. tsutsugamushi)
Microbiology
null
c19a3356-65ca-42d3-8dd6-527adfbe3011
Inferior angle of scapula is at what level of rib
5th
6th
7th
8th
2c
single
The eighth rib is just below the inferior angle of the scapula. The lower ribs can be identified on the back by counting down from the eighth rib so at the level of inferior angle of scapula is related to 7th rib. Ref : B D Chaurasia's Human Anatomy , seventh edition ,volume 1 , pg. no., 62
Anatomy
Upper limb
f8c8c619-30e9-45c5-95a9-5f43476ed3b6
Which of the following is the COMMONEST cause of pyometra?
Carcinoma ovary
Carcinoma cervix
Carcinoma vagina
Uterine myoma
1b
single
Pyometra refers to filling of the uterine cavity with pus. It occurs due to a blocked cervical canal in conditions such as cervical carcinoma or postmenopausal stenosis, it can also occur in senile endometritis, cancer of body of uterus, and puerperal endometritis.. In this condition, the cavity of distended uterus is ...
Gynaecology & Obstetrics
null
eef4462d-66fb-4571-b3a6-e18406973276
Osiander's sign means :
Pulsation in the lateral vaginal fornix
Bluish colour change in the vagina
Softening of the cervix
On bimanual palpation the finger can be approximated as if nothing is in between
0a
single
Pulsation in the lateral vaginal fornix
Gynaecology & Obstetrics
null
8b531e09-b7cd-4564-acd4-bcbed350ac0e
Sweat glands are which types of gland ?
Simple tubular
Simple coiled tubular
Compound tubular
Compound acinar
1b
single
Ans. is 'b' i.e., Simple coiled tubular
Anatomy
null
6f7492e9-c8e0-4f74-8da8-48ee013039c2
Excitatory neurotransmitter of brain is?
GABA
Aspartate
Glutamate
Glycine
2c
single
Ans. C Glutamate* The most prevalent transmitter is glutamate, which is excitatory at well over 90% of the synapses in the human brain.* The next most prevalent is Gamma-Aminobutyric Acid, or GABA, which is inhibitory at synapses in the human brain.
Physiology
Nervous System
fcc8c1bf-17d6-4a88-be61-3ca932c6326e
True about late onset schizophrenia:
Onset after 45 yrs
Onset between 25-30 yrs
Prognosis is poor
Olfactory hallucinations are common
0a
multi
A i.e. Onset after 45 yrsLate onset schizophrenia is characterized by onset after age 45 years, more frequent female involvement, predominance of paranoid symptoms, ourable prognosis and patients usually do well on antipsychotic medicationQ. Late Onset Schizophrenia (LOS) & VeryLate Onset Schizophrenia (VLOS) - Accordi...
Psychiatry
null
7a7de14d-82e6-4978-87e6-015345fc9aed
Antigen which does not appear in blood in hepatitis B:
HbcAg
HbeAg
HbsAg
None of the above
0a
multi
Because HBcAg is intracellular and, when in the serum, sequestered within an HBsAg coat, naked core paicles do not circulate in serum and, therefore, HBcAg is not detectable routinely in the serum of patients with HBV infection. By contrast, anti-HBc is readily demonstrable in serum, beginning within the first 1-2 week...
Medicine
Hepatitis
9c3b794c-a78d-4718-aa3b-36be1352003e
Bih rate is
Live bih X 1000\/ mid yr. Population
Bih X 1000\/ mid yr population
Live bih X 10000\/ mid yr. Population
Live bih X 10000\/Population of reproductive age group (15-45)
0a
single
Bih rate = number of live bihs during the year X 1000/ estimated mid year population. Unsatisfactory measure of feility because the total population is not exposed to child bearing. Reference : Park&;s textbook of preventive and social medicine, 23rd edition, pg no: 488
Social & Preventive Medicine
Demography and family planning
96c4528a-2864-48cc-8f3c-c538e931b089
Pear-shaped trophozoite with undulating membrane is characteristic features of
Trichomonas Vaginalis
Giardia - Iambiia
African trypanosomiasis
Enteromonas hominis
0a
single
(Trichomonas vaginalis) (37-P) (40- Paniker 6th)Trichomonas vaginalis - occurs only as the trophozoite there being no cystic form in trichomonas. The trophozoite is ovoid or pear shaped, broad with short undulating membrane reaching uptop the middle of the body. It has 4 anterior flagella and fifth running along the ou...
Microbiology
Parasitology
e5f1f933-d2f2-41c4-84b5-2a892e57ac1e
A child suffering from asthma is to be treated with a drug that blocks the synthesis of leukotrienes. What drug would be an appropriate choice
Cromolyn sodium
Montelukast
Zileuton
Theophylline
2c
single
zileuton mech of action:- It is a 5-LOX(lipoxygenase) inhibitor, blocks LTC4/D4 as well as LTB4 synthesis. It therefore has the potential to prevent all LT induced responses including those exeed by activation of cysLT1 receptor. Duration of action of zileuton is sho. side effects:- Hepatotoxicity
Pharmacology
Respiratory system
cf5b8923-cb7e-4dd0-913f-ed09945ea2cd
Mobitz II hea block is seen with all except?
Hypothyroidism
Coronary aery disease
Sarcoidosis
Cushing syndrome
3d
multi
Mobitz II | Damage to BOH at infranodal site Option A- Hypothyroidism - myxedema- Mobitz II Option B- Coronary aery disease= Ischemic - Mobitz II Option C- Sarcoidosis= Non caseating granuloma- Mobitz II
Medicine
NEET 2018
1c10a99b-84f4-48aa-92e3-2ba5a01f6a61
Hot Cross Bun Sign on MRI is seen in-
Multisystem atrophy
Lewy body dementia
Progressive supranuclear palsy
Alzeihmer's disease
0a
single
* HOT CROSS BUN SIGN - cross shaped hyperintensity in the center of pons * It is a classic feature of Multisystem atrophy type - C * Multisystem atrophy type - c has involvement of pontocerebellar pathway Figure: hot cross bun sign - MSA-C Figure showing Humming bird sign in Progressive supranuclear palsy. Figure showi...
Radiology
Magnetic Resonance Imaging
5761272e-45b1-4155-a216-c9e7a90be357
A drug is more likely to cause toxicity in elderly patients due to all of the following reasons EXCEPT:
decreased renal excretion of drugs
decreased hepatic metabolism
increased receptor sensitivity
decreased volume of distribution
3d
multi
Ans. is 'd' ie decreased volume of distribution Volume of distribution is increased with aging. This leads to decreased elimination of the drug and hence increased toxicity.Other changes seen with aging which lead to increased toxicity of drugsincreased sensitivity of the target organs*decreased renal excretion of drug...
Pharmacology
Pharmacodynamics
cca15142-7e16-447c-9350-0f42a15333aa
Carbamoyl phosphate is used in-
Urea
Uric acid
Pyruvic acid
Stearic acid
0a
single
Ans. is 'a' i.e., Urea o Carbamoyl phosphate is used in the synthesis of urea (urea cycle).Aspartate - NH. (or NH4+) + CO, + H,0 + 3 ATP - Fumarate + Urea + 2 ADP + 2Pi + AMP + PPio Kidney and intestine contribute to most of body arginine because they posses all the urea cycle enzymes except arginase.o Brain can synthe...
Biochemistry
Urea Cycle and Disorders