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pair_31570685 | According to the literature and expert experience, a comprehensive index system of subjective and objective was established, including the patient's condition, the treatment information for the same kind of patients, technical level of the medical team, and the medical conditions. Secondly, in the light of the heteroge... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 首先基于文献资料和专家经验,建立包括直肠癌患者病情、同类患者的历史治疗信息、医疗团队的技术水平和医疗条件等内容的主客观指标体系;接着针对异质信息,确定主观权重与客观熵权相结合的综合指标权重;然后采用多准则妥协解排序(Vlsekriterijumska Optimizacija I Kompromisno Resenje,VIKOR)方法处理异质评价信息,得到针对直肠癌患者的手术方案优先次序。运用此方法对湖南某三甲医院的1例直肠癌患者进行手术方案选择决策,得到的最适合该患者的手术方案与实际治疗方案一致。由应用实例可知基于概率语言的异质VIKOR方法在直肠癌手术方案的选择中具有有效性及可靠性,可帮助医生、患者及患者家属选择手术方案。. | zh-cn |
pair_31570686 | Benign metastasizing leiomyoma (BML) often occurs in women with a history of uterine leiomyoma at the childbearing age. At the same time, BML cases with multiple sites of metastatic lesions are extremely rare. A BML patient with multiple metastases of uterine leiomyoma in two lung and lumbar spine after surgery was adm... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 良性转移性平滑肌瘤(benign metastasizing leiomyoma,BML)常发生于育龄期有子宫平滑肌瘤手术史的女性患者。同时出现多个部位转移病灶的BML病例极为罕见,中南大学湘雅二医院脊柱外科于2017年9月收治1例子宫平滑肌瘤术后两肺与腰椎BML多发转移患者。正电子发射计算机断层显像/计算机体层摄影(positron emission tomography/computed tomography,PET/CT)能进行全身检查,且可发现BML患者肺、腹腔、盆腔、脊椎等多部位出现的转移灶,有利于做出全面诊断。现结合该病例的特点及相关文献报道探讨BML的影像学及临床特点。. | zh-cn |
pair_32227646 | Mortality of animals on roads is a critical threat to many wildlife populations and is poised to increase strongly because of ongoing and planned road construction. If these new roads cannot be avoided, effective mitigation measures will be necessary to stop biodiversity decline. Fencing along roads effectively reduces... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 动物被路杀是许多野生动物种群面临的一项严重威胁。考虑到正在进行和计划实施的道路建设, 这一问题还将日益加剧。如果无法避免建设新道路, 就必须采取有效的缓解措施来阻止生物多样性下降。在道路两旁修建围栏可以有效减少路杀, 且经常与野生动物通道结合使用。由于资金限制, 通常不能沿整条道路设置围栏, 因此一般会找出路杀高发地段来为围栏的布设提供信息。我们设计了一个适应性的围栏建设实施计划, 来确定优先建设围栏的路段。在这个框架中, 我们在多尺度上 (即在 200-2000 米直径的圆内测量路杀死亡率) 确定了路杀频率高、中、低的道路沿线地区 (分别是路杀热点地区、暖点地区和冷点地区) 。围栏布设是基于道路上从路杀热点地区开始的增加围栏的数量... | zh-cn |
pair_32227646 | Mortality of animals on roads is a critical threat to many wildlife populations and is poised to increase strongly because of ongoing and planned road construction. If these new roads cannot be avoided, effective mitigation measures will be necessary to stop biodiversity decline. Fencing along roads effectively reduces... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Un Plan Adaptativo para la Priorización de Secciones de Carretera para Cercar y Reducir la Mortalidad Animal Resumen La mortalidad de los animales en las carreteras es una amenaza muy importante para las poblaciones silvestres y se pronostica que aumentarán enérgicamente debido a la construcción continua y planeada de ... | es |
pair_32233087 | Maintaining a living plant collection is the most common method of ex situ conservation for plant species that cannot be seed banked (i.e., exceptional species). Viability of living collections, and their value for future conservation efforts, can be limited without coordinated efforts to track and manage individuals a... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 保存植物活体是对不能贮存种子的植物 (特殊植物) 最常用的迁地保护方法。然而, 如果没有跨机构的生物个体跟踪和管理的协作, 活标本的生存能力及其对未来保护工作的价值可能会受到限制。动物保护团体利用基于系谱的方法建立了一套跨机构的基础工具来支持圈养动物种群的长期生存。本研究评估了这种协作性的聚合采集基础工具在支持保护四种在全球多个植物园存有活标本的植物的能力。结果表明, 当前的保护实践的局限性包括无法在生物个体水平汇编、分享和分析采集植物的数据, 以及难以追踪迁地保护植物的原始种源。植物保护团体可以采用动物园使用的协作性聚合采集框架, 通过减少采集过程中遗传多样性丧失来改善保护结果。我们建议采取行动来推动特殊植物物种的迁地保护, 包括... | zh-cn |
pair_32233087 | Maintaining a living plant collection is the most common method of ex situ conservation for plant species that cannot be seed banked (i.e., exceptional species). Viability of living collections, and their value for future conservation efforts, can be limited without coordinated efforts to track and manage individuals a... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Aplicación del Modelo Zoológico a la Conservación de Especies Excepcionales de Plantas Amenazadas Resumen El mantenimiento de una colección de plantas vivas es el método más común para de conservación ex situ para especies de plantas que no pueden almacenarse en bancos de semillas (i. e., especies excepcionales). La vi... | es |
pair_32233119 | We devised a practical method for integrating information on 2 marine invasive species using 3 different approaches: standardized ecological monitoring, online-reporting databases, and surveys of anglers and crabbers. Focusing on 2 recently introduced species with different characteristics, the Asian shore crab (Hemigr... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 本研究利用了三种不同的手段设计了一种实用方法来整合两种海洋入侵物种的信息, 包括: 标准化生态监测、在线报告数据库, 以及对钓鱼者和捕蟹者的调查。我们聚焦于纽约和新泽西 Hudson-Raritan 流域最近出现的两种具有不同特征的入侵物种, 肉球近方蟹 (Hemigrapsus sanguineus) 和中华绒螯蟹 (Eriocheir sinensis), 并使用敏感性分析来探索每个信息源对物种丰度和分布范围知识的相对贡献。三个信息来源都对了解外来引入的螃蟹数量和分布做出了独特的贡献。对肉球近方蟹的在线报告数据和调查数据对丰度预测有显著影响, 而生态监测数据则没有。当忽略调查数据时, 丰度估计值不会随时间变化, 而包括调查数据则... | zh-cn |
pair_32233119 | We devised a practical method for integrating information on 2 marine invasive species using 3 different approaches: standardized ecological monitoring, online-reporting databases, and surveys of anglers and crabbers. Focusing on 2 recently introduced species with different characteristics, the Asian shore crab (Hemigr... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Acoplamiento entre los Dominios de Información para Mejorar el Entendimiento Ecológico de las Invasiones Biológicas en un Ecosistema Marino Resumen Diseñamos un método práctico para integrar la información sobre dos especies marinas invasoras usando tres estrategias diferentes: el monitoreo ecológico estandarizado, las... | es |
pair_32234125 | Malignant melanoma is a kind of tumor produced by human melanocytes. It has a high degree of malignancy, early metastasis and high mortality. Most melanomas are caused by malignant skin nevus and can also be seen in the digestive tract such as rectum and anus. Primary malignant melanoma of pleura is rare, rarely seen i... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 【中文题目:胸膜恶性黑色素瘤:1例报告及文献复习】 【中文摘要:恶性黑色素瘤是由人体黑色素细胞产生的肿瘤,其恶性程度高,转移发生早,患者死亡率高,多数恶性黑色素瘤是由人体皮肤黑痣恶变产生的,少数也可见于直肠和肛门等消化道。原发于人体胸膜的恶性黑色素瘤十分罕见,偶见于病例个案报道。现报道1例首都医科大学附属北京友谊医院应用胸腔镜联合病理确诊的以咳嗽、咳痰及胸腔积液为首发症状的恶性黑色素瘤患者的临床资料,并结合文献资料进行分析总结。】 【中文关键词:恶性黑色素瘤;胸膜;胸腔镜】. | zh-cn |
pair_32234126 | The diagnosis of COVID-19 is based on the positive of etiological test. The current etiological test of COVID-19 cost long time, and have high false negative rate, may resulting delay the measures of disease treatment and prevention. We suggested that COVID-19 should be diagnosed as 3 types: suspected case, clinical di... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 新型冠状病毒肺炎的诊断是以病原学检测阳性为确诊标准的,由于现有的病原学检测耗时较长,假阴性率较高,致使疑似病例的确诊时间延长,从而延误后续防治。本文建议将该病的诊断标准分为疑似病例、临床诊断病例和确诊病例3类。. | zh-cn |
pair_32234129 | During the fighting against COVID-19, both the public health education and public health workforce of China have exposed important challenges. The present review discusses dilemmas and weakness that relate to the position of public health education in the higher education system, public health education system, curricu... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 在抗击新型冠状病毒肺炎疫情的过程中暴露出我国公共卫生教育与疾控人才队伍的建设存在很多问题和短板。本文围绕着我国公共卫生教育在高等教育中的定位,公共卫生教育体系、课程体系和教学方法、实践教学,公共卫生高层次人才培养,公共卫生师资,以及公共卫生人才待遇和政策导向等方面,思考面临的困境和存在的短板,并提出相关建议。. | zh-cn |
pair_32234130 | The outbreak of 2019-novel coronavirus (2019-nCoV) infection poses a serious threat to global public health. Vaccination is an effective way to prevent the epidemic of the virus. 2019-nCoV along with severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) bel... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 新型冠状病毒(2019-nCoV)感染暴发流行对全球公众健康构成了严重威胁,疫苗接种是有效预防病毒感染流行的手段。2019-nCoV与急性呼吸综合征冠状病毒(SARS-CoV)和中东呼吸综合征冠状病毒(MERS-CoV)同属于β-冠状病毒。基于对SARS-CoV和MERS-CoV的了解,科学家对2019-nCoV病毒特征的研究、候选抗原及表位的鉴定、动物模型的建立、免疫应答的检测,疫苗的设计等工作取得了快速进展。新型冠状病毒疫苗(新冠疫苗)的研发也取得了快速进展,新冠疫苗类型几乎涵盖了目前疫苗研究的所有形式,包括灭活疫苗、重组蛋白疫苗、病毒载体疫苗、核酸疫苗(mRNA疫苗与DNA疫苗)等。至2020年3月,已有2项新冠疫苗进入了Ⅰ期... | zh-cn |
pair_32237533 | As an important strategy for sustainable development, bioremediation technology has been widely used in soil contamination remediation due to the advantages of environmental friendliness, excellent metal removal efficiency and free of secondary pollution. This special issue with a collection of 16 papers covers the res... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 生物修复技术,作为可持续发展的重要方向,因其环境友好、高效且无二次污染并能从根本上解决土壤污染问题而受到关注,已经在土壤污染治理中得到了广泛的应用。为了梳理和凝练生物修复技术的发展状况,本专刊收录了该研究领域的16 篇论文,分别从植物修复、微生物修复、联合修复、重金属吸收积累的相关分子机制、资源化再利用等方面,详细阐述生物修复技术的发展动态,展望未来的发展趋势,为促进生物修复技术的发展提供参考。. | zh-cn |
pair_32237534 | Arsenic is a toxic metalloid. Arsenic pollution in soils affects food safety and threatens human health. Pteris vittata L. has enormous application value in phytoremediation of arsenic-contaminated soil for its high arsenic hyperaccumulation ability. Understanding the arsenic hyperaccumulation molecular mechanism of P.... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 砷是一种毒性很强的类金属元素,土壤砷污染可引发一系列食品安全问题,进而威胁人类健康。蜈蚣草具有极强的富集砷的能力,在砷污染土壤的植物修复中具有重要的应用价值。深入阐释蜈蚣草超富集砷的分子机制是植物修复技术的核心理论基础。文中综述了蜈蚣草超富集砷的组学研究进展,以及目前鉴定到的砷富集过程中的重要分子元件,并对未来的研究方向和趋势进行了展望。. | zh-cn |
pair_32237535 | Common submerged plants (Vallisneria natans (Lour.) Hara., Potamageton crispus L., Myriophyllum spicatum L., Ceratophyllum demersum L. and Hydrilla verticillata (L.f.) Royle) have shown a tremendous potential for arsenic removal from water. The studies on the accumulation of arsenic by submerged plants are important fo... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 常见的沉水植物 (苦草、狐尾藻、金鱼藻、黑藻) 对水体中的砷 (As) 有着较强的富集能力,研究沉水植物对As 的富集特征对利用沉水植物控制水体As 污染及保护人体健康有着重要意义。沉水植物对As 的富集能力与水环境中As 的浓度、形态、共存离子如磷酸盐、Zn 离子等因素相关,其对As 的耐受性及富集能力可以通过合适的化学、生物方法得到增强,从而提高沉水植物对含As 污水的修复能力。但由于植物基因多样性及水环境因素复杂性,沉水植物对As 的运输和解毒机制,以及沉水植物后期的处理和管理技术,仍是今后该领域需要重点关注的问题。. | zh-cn |
pair_32237536 | Phytoremediation is one of the important methods for restoring heavy-metal contaminated soils. Using high-biomass economic plants to restore heavy-metal contaminated soils can have both ecological and economic benefits, with great application prospects. Based on the analysis of current situation and existing problems o... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 植物修复是重金属污染土壤修复的重要方法之一。利用高生物量经济植物修复重金属污染土壤,能够兼顾生态和经济效益,具有很大的应用前景。本文系统分析了植物修复现状及存在的问题,提出利用高生物量经济植物修复重金属污染土壤的优势,总结了近年来利用高生物量经济植物吸收重金属的研究进展,探讨了改善高生物量经济植物修复重金属污染土壤效率的方法,以期为提高植物修复经济效益、促进植物修复广泛应用提供参考。. | zh-cn |
pair_32237537 | With the development of modern industry, heavy metal pollution of soil becomes more and more serious. Heavy metals can cause serious health problems to humans and animals even at very low concentrations. Thus, it is urgent to remediate the contaminated soils by effective methods. Different remediation strategies have b... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 随着近代工业的发展,土壤重金属污染问题日益严重。重金属即使在极低浓度下仍然可以对人畜造成健康上的威胁,因此迫切需要有效的修复方法对土壤进行修复。生物修复,特别是植物修复目前已经成为重金属污染修复的重要手段之一,了解相关植物的重金属解毒和积累分子机制是提高修复效率、解决重金属污染问题的基础。文中以土壤修复方式为起点,结合植物吸收积累重金属以及解毒的相关分子机制研究,探讨了植物修复的发展现状以及趋势。. | zh-cn |
pair_32237538 | Phytomining technology cultivates hyperaccumulator plants on heavy metal contaminated soils, followed by biomass harvesting and incineration to recover valuable metals, offering an opportunity for resource recycling and soil remediation. Large areas of ultramafic soils, naturally rich in nickel (Ni), are present in num... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 植物采矿是利用超积累植物高量吸收土壤中的重金属,并从中提取、冶炼金属产品,在修复污染土壤的同时实现金属的资源化。全世界广泛分布着自然风化的镍污染土壤,植物采矿因其重要的环境、生态及资源价值,被作为一种环境友好且具备经济效益的土壤修复技术,在此类地区具有广阔的应用前景。该植物采矿技术关键过程主要包括超积累植物镍高选择性根际环境响应、植物镍高效吸收转运以及生物质中镍高附加值资源化等过程。近30 年,污染土壤中镍的植物采矿已经在美国、阿尔巴尼亚、马来西亚等多个国家进行了野外实践,取得了良好效果。然而,相关技术在我国的研究与应用仍然处于起步阶段。文中通过综述植物采矿技术的关键过程的研究进展,发现其中的瓶颈,为接下来植物采矿的科学研究和技术在... | zh-cn |
pair_32237539 | Arsenic-resistant microorganisms are abundant in surface and near-surface arsenic-contaminated environment, substantially affecting the fate and transport of arsenic in the environment. Siderophores produced by microorganisms under iron-limiting conditions have high affinity for ferric iron and enhance the uptake of ir... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 在砷污染环境中,许多微生物进化出了砷抗性,对地球环境中砷的命运起着决定性的作用。其次,由于自然条件下铁有效浓度低,微生物一般会表达嗜铁素,协助微生物吸收铁。嗜铁素除了与铁结合外,还可与多种金属离子形成稳定的复合物,促进环境中砷酸盐的溶解和亚砷酸盐的氧化。最后,产嗜铁素微生物有促进植物生长和促进或减弱植物吸收砷的可能性。因此,产嗜铁素砷抗性微生物可能具有在砷污染环境的修复中发挥作用的潜力。. | zh-cn |
pair_32237540 | Soil is the material basis for human survival. However, in China, soils are wildly polluted by heavy metals, which poses serious health risks to humans. Bioremediation of heavy-metal contaminated soil is widely considered as a sustainable remediation strategy, but low remediation efficiency is still a scientific bottle... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 土壤是人类赖以生存的物质基础。我国土壤重金属污染状况不容乐观,给人类健康构成严重威胁。生物修复重金属污染土壤被广泛认为是可持续的修复技术,但当前仍存在修复效率不高的科学瓶颈问题。土壤中生活着丰富的微生物、植物和动物,且这些生物之间存在着复杂的相互作用,并且通过物质循环和能量传递形成了错综复杂的食物网联系。土壤生物间的相互作用能深刻影响土壤中污染物的迁移转化和生物修复的效率,多元生物协同的修复技术集合了单一生物修复方法的优势,具有强化生物修复效果的巨大潜力。文中综述了土壤中微生物-植物-动物之间的相互作用,及其对土壤重金属迁移转化和生物修复效果的影响,并对定向调控土壤食物网结构、提高重金属污染土壤的生物修复效果、建立基于食物网的多元生... | zh-cn |
pair_32237541 | With the acceleration of industrialization and agriculture, soil heavy metal pollution has become increasingly serious. Copper, though an essential trace element for the growth and development of living organisms, is one of the main heavy metal pollutants. Excess copper in soil is toxic to plants and threatens human he... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 随着工业化与农业化进程的加快,土壤重金属污染问题日益突出。铜 (Cu) 既是生命体生长发育的必需微量元素,也是重金属污染物之一。土壤中过量的Cu 不仅会对植物产生毒害,而且能够通过食物链的富集作用,对人类健康造成严重威胁。生物修复技术作为治理重金属污染土壤的一种新型技术受到广泛关注。文中对生物修复的主要技术如植物修复、微生物修复、植物-微生物联合修复、动物修复等在治理Cu 污染土壤方面的研究进展进行综述,以期为重金属污染土壤有效治理和可持续农业的发展提供理论依据。. | zh-cn |
pair_32237542 | Coastal and inland saline-alkali soil is important reserve land resources. However, some parts of saline land are now under the threat of heavy metals such as cadmium (Cd), lead (Pb) and the light metal lithium (Li). Phytoremediation with halophytes could be the most economical and effective way to restore the contamin... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 滩涂和内陆盐碱地是重要的后备土地资源。近年来镉 (Cd)、铅 (Pb) 等土壤重金属和锂 (Li) 污染对盐碱地开发利用和生产安全造成严重威胁。利用盐生植物修复污染盐土是最经济有效的方法。本研究以盐生植物盐角草Salicornia europaea L.为材料,采用盆栽方式,通过比较分析盐角草在不同浓度Cd (0−50 mmol/L)、Pb(0−50 mmol/L)和Li (0−400 mmol/L) 处理下的生长和生理生化指标及离子含量的变化,研究盐角草对3 种金属污染物胁迫的耐性及积累特性,以期探讨盐角草在Cd、Pb、Li 污染盐土修复中的应用潜力。结果显示,随着Cd、Pb 处理浓度升高,盐角草的株高、鲜重和干重均显著下降。低浓... | zh-cn |
pair_32237543 | Nickel and copper, as high toxic heavy metals (HMs), are the most serious contaminants in Jinchuan mining area, China. In this paper, the influence of combined HMs stress on the growth of widespread plant-S. salsa has been studied. The stress gradient of combined Ni-Cu was set based on the local environment and pre-exp... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 为探究重金属复合胁迫对金川镍铜矿区广布植物碱蓬Suaeda salsa (L.) Pall.的影响,根据当地环境条件及预实验结果设置胁迫梯度,测定分析重金属胁迫下碱蓬种子萌发和芽期生理指标,并从野外站台取样研究碱蓬重金属富集能力。结果表明:无论是单一胁迫还是低浓度复合胁迫 (Cu20 和Ni20 复合),发芽期碱蓬的生长均呈现“低促高抑”的趋势,即低浓度 (≤40 mg/L) 时促进碱蓬生长,高浓度 (≥80 mg/L) 时抑制碱蓬生长;高浓度复合胁迫(Cu320 和Ni320 复合) 下均抑制碱蓬的生长。MDA (丙二醛) 的含量随胁迫浓度的增加而增加;胁迫组可溶性蛋白和游离脯氨酸含量整体上高于对照组;单一胁迫下POD (过氧化物... | zh-cn |
pair_32237544 | In this study, pot and field experiments were conducted to study the enrichment of soil cadmium by Kochia scoparia. Further, rotations in pot experiments were carried out with four varieties of Brassica rapa to verify the remediation effect of Kochia scoparia on cadmium contamination in soil. The enrichment capacity of... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 通过盆栽和大田试验研究扫帚菜Kochia scoparia 对土壤中镉 (Cd) 的富集效率,并利用盆栽试验将其与4 个白菜品种进行轮作试验,验证扫帚菜对土壤Cd 污染的修复效果。结果表明,扫帚菜各部位富集能力表现为叶>根>茎,富集系数分别为15.07、5.44 和2.96;种植扫帚菜后土壤总Cd 降低6.02%−13.60%;土壤脲酶和酸性磷酸酶活性也有所提高。盆栽轮作结果表明,扫帚菜-白菜轮作系统中白菜地上部Cd 含量与未轮作的对照组相比平均降低17.21%,生物量有略微增加,地上部对Cd 的转运系数无明显变化。结果显示,通过扫帚菜与白菜轮作不仅可以增加白菜产量,而且可以有效降低白菜可食部Cd 含量,实现边生产边治理的绿色农业理... | zh-cn |
pair_32237545 | In order to explore the effect of intercropping on the uptake of heavy metal cadmium (Cd), pot experiments were undertaken using three different planting methods: monoculture, restrictive intercropping and intercropping. The effects of Cd accumulation in different plant parts, and their causes, were examined using a pl... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | None | zh-cn |
pair_32237546 | To explore the effects of some chemical amendments on the plant growth and phytoextraction efficiencies of cadmium (Cd)/zinc (Zn) hyper accumulator Sedum plumbizincicola in acid soils with high aluminum (Al) toxicity, a greenhouse pot experiment was conducted. Different kinds and dosages of amendments including calcium... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 为探究不同改良剂对酸性土壤铝 (Al) 胁迫条件下镉 (Cd) 锌 (Zn) 超积累植物伴矿景天Sedum plumbizincicola 生长以及镉和锌吸取修复效率的影响,分别添加不同种类改良剂 (钙镁磷肥 (CMP)、MgCO₃、KH₂PO₄) 和不同浓度CMP 进行温室盆栽试验。结果表明,CMP 能够一定程度上提高土壤pH 值并降低土壤交换性Al 的浓度,MgCO₃ 能够显著提高土壤pH 值和降低土壤交换性Al 的浓度,KH₂PO₄ 能够降低土壤中交换性Al浓度但未改变土壤pH 值。施用适量的CMP (9.39 mg/kg) 能够提高伴矿景天生物量和Cd、Zn 吸取修复效率,用量过高会抑制伴矿景天生长和Cd、Zn 修复效率;施... | zh-cn |
pair_32237547 | Hyperaccumulators can hyper-accumulate and -tolerate heavy metals, thus are not only an ideal model to explore the mechanisms of ion transport and toxicity tolerance, but also play an irreplaceable role in the development and application of phytoremediation. Sedum plumbizincicola is a recently identified cadmium (Cd)/z... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 超积累植物由于其对重金属具有地上部超积累以及超耐受等特性,不仅是研究植物离子转运及毒性耐受的理想模式,而且在植物修复的发展和应用中具有不可替代的作用。伴矿景天是近年在我国境内发现的一种景天科镉 (Cd)/锌 (Zn) 超积累植物。为鉴定其富集和耐受Cd 的关键基因,笔者构建了其酵母表达cDNA 文库,利用酵母的遗传互补系统筛选到一个极大提高了酵母抗Cd 能力的基因SpMT2。SpMT2 属于富含半胱氨酸 (Cys) 的金属硫蛋白 (Metallothionein) 家族。亚细胞定位表明SpMT2 表达于酵母细胞质中,并特异地提高酵母对Cd 的抗性。进一步研究发现SpMT2 的表达显著降低了酵母液泡中Cd 含量,但酵母吸收的总Cd 含... | zh-cn |
pair_32237548 | Sedum plumbizincicola is a native cadmium/zinc (Cd/Zn) hyperaccumulator in China. At present, it has been applied to remediation of Cd contaminated soils. As the large differences in the removal efficiency of Cd and Zn for different soil conditions, the enhancement measure is important for the phytoremediation process.... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 伴矿景天Sedum plumbizincicola 是我国发现和报道的镉/锌 (Cd/Zn) 超积累植物,在土壤Cd 污染修复方面已开展实际应用。由于超积累植物伴矿景天在不同类型土壤下的生长能力以及对镉锌的去除效果存在较大差异,因此需引入强化修复技术为植物修复提供辅助作用。作为大型土壤动物,蚯蚓对植物生长的促进作用已有较多研究,但其对伴矿景天生长和重金属吸取效率的影响则鲜有报道,为探究赤子爱胜蚓对不同类型土壤种植下的伴矿景天是否具有强化修复效应,以及不同类型土壤下的强化修复效应差异,设计以下盆栽试验。通过在常湿淋溶土 (Perudic Luvisols)、水耕人为土 (Stagnic Anthrosols)、湿润雏形土 (Udic ... | zh-cn |
pair_32237549 | In order to solve the problem of soil, water pollution and sensitive crop drug damage caused by chlorosulfuron residue, and to provide degradation strain resources for microbial remediation of contaminated soil, a chlorimuron-ethyl-degrading strain T9DB-01 was isolated from chlorosulfuron contaminated soil by the metho... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 为解决氯嘧磺隆残留对土壤、水体污染及后茬敏感作物药害问题,为污染土壤微生物修复提供降解菌种资源,文中采用富集培养、逐级驯化等方法,从氯嘧磺隆污染土壤中分离到1 株高效氯嘧磺隆降解菌T9DB-01,经形态特征、生理生化及16S rDNA 序列分析,鉴定为假单胞菌Pseudomonas sp.。采用单因素实验探究温度、pH值、底物浓度、装液量和接种量对菌株T9DB-01 降解氯嘧磺隆的影响,采用正交试验及验证,优化菌株T9DB-01对氯嘧磺隆降解条件。结果表明,在30 ℃,pH 8.0,底物浓度200 mg/L,装液量100 mL/250 mL,接种量4%的条件下,5 d 后降解率达到93.7%。该降解菌株对氯嘧磺隆污染土壤原位生物修复... | zh-cn |
pair_32238232 | COVID-19 is an infectious disease caused by 2019-nCoV and characterizes as an atypical pneumonia. Since 2019-nCoV is a newly emerging virus, the pathogenesis of COVID-19 is not well known. Most patients had a self-limited course, and some became severe even death. In this review, the authors compared two coronavirus ou... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 新型冠状病毒感染疾病(COVID-19)是一种由新型冠状病毒(2019-nCoV)引起的传染病,基本特征以肺部炎性病变为主。目前正在全球迅速蔓延。该文比较近二十年间发生的两次人类冠状病毒严重急性呼吸综合征(SARS)和COVID-19的病原特点、受体分布、临床表现和病理改变,试图揭示COVID-19的病理生理机制,为治疗患者和疫情管控提供新思路。分析表明,由于2019-nCoV和SARS冠状病毒在人体细胞上有相同的受体(ACE2),因而它们可能有相同的靶器官,如肺、心血管系统和免疫系统。病理改变除了病毒直接损伤靶器官中的功能细胞外,还与病毒诱导靶细胞产生促炎因子造成局部严重炎性反应有关。同时,促炎因子还过度激活了免疫细胞尤其是单核-... | zh-cn |
pair_32241040 | Since the discovery of fibroblast growth factor (FGF) in the early 20th century, the multiple regulatory function of FGF has been found in development, metabolic regulation and tissue regeneration. Although FGF has the potential in wound healing of clinical practice, several technical bottlenecks occurred in the develo... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 自20世纪初发现成纤维细胞生长因子(FGF)后,研究发现其在发育、代谢调控和组织再生等方面均发挥着重要作用。FGF治疗可成为创面修复重要的疗法之一,然而在其成药过程中却遭遇了重大技术瓶颈。自1992年开始,笔者团队不断突破FGF成药技术瓶颈,成功开发多个一类新药及医疗器械。与此同时还深入研究FGF的代谢调控网络及信号转导机制,努力开发FGF新药,造福广大患者。. | zh-cn |
pair_32241041 | Autologous split-thickness skin grafting is still an important procedure for the repair of skin defect. However, there are some obvious limitations, such as new injury to skin donor sites and insufficient skin source, etc. It is an ideal goal to develop tissue-engineered skin to realize permanent replacement of skin de... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 自体断层皮片移植仍是修复皮肤缺损的重要方法,但存在一些明显的不足,如供皮区损伤、皮源不足等。研发组织工程皮肤实现缺损皮肤的永久性替代是一个理想目标。经过几十年的发展,多种组织工程皮肤已被投入市场使用,但要实现皮肤缺损的再生修复还有很长的路要走。本文总结组织工程皮肤的现状,并对组织工程皮肤发展所面临的机遇和挑战做初步探讨。. | zh-cn |
pair_32241051 | The early accurate diagnosis of burn depth is of great significance in determining the corresponding clinical intervention methods and judging the prognosis quality of burn patients. However, the current diagnostic method of burn depth still relies mainly on the empirical subjective judgment of clinicians, with low dia... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 烧伤深度的早期精确诊断对决定相应的临床干预手段和判断烧伤患者预后质量具有重要意义。然而目前烧伤深度的诊断仍主要依靠临床医师的主观经验性判断,准确率低,尤其对于深Ⅱ度烧伤创面,早期诊断误差较大。近年来,人工智能技术发展迅速,深度学习算法结合图像分析技术能够更好地识别、分析医学图像信息。本文将对人工智能技术在烧伤深度诊断方面的研究进展进行综述。. | zh-cn |
pair_32241052 | In order to improve the overall therapeutic effect of gallbladder cancer in China, Branch of Biliary Surgery, Chinese Surgical Society and Chinese Committee of Biliary Surgeons have formulated the guideline for the diagnosis and treatment of gallbladder carcinoma (2019 edition) . The guideline provided an overview of t... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 为提高我国胆囊癌总体治疗效果,中华医学会外科学分会胆道外科学组、中国医师协会胆道外科专业委员会制订了《胆囊癌诊断和治疗指南(2019版)》。该指南明确了胆囊癌发病的危险因素及干预方法、随访流程,描述了胆囊癌TNM最新分期,并提出了胆囊癌的临床分型。基于现代高质量影像技术和内镜技术可精准评估胆囊癌分期和分型,对进展期胆囊癌应贯彻综合治疗的理念,进行多学科讨论,科学决策治疗手段。胆囊癌的外科治疗应在具有丰富经验的肝胆胰外科医师和病理科医师的医疗中心完成,合理选择手术技术平台,实施规范的胆囊癌根治性切除术;化疗、放疗、靶向治疗及免疫治疗的结合应用可改善胆囊癌患者的预后,但仍需进一步研究使胆囊癌患者获得更大生存获益。. | zh-cn |
pair_32241053 | Iron deficiency anemia is common in general surgery patients during the perioperative period, which will increase the morbidity and mortality. Timely diagnosis and treatment of iron deficiency anemia in the perioperative period will improve the clinical outcome of patients and reduce the medical burden.Management of pe... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 普通外科患者在围手术期常见缺铁性贫血,缺铁性贫血会增加围手术期并发症发生率和病死率。围手术期及时诊断及治疗缺铁性贫血有助于改善患者临床转归,减轻医疗负担。围手术期缺铁性贫血管理的措施包括熟悉贫血的诊断及分级,监测患者血红蛋白,治疗贫血病因,营养支持,补充铁剂,实施限制性输血策略,应用促红细胞生成素,自体血回输等。本共识推荐通过多学科合作,诊断和治疗普通外科患者围手术期的缺铁性贫血。. | zh-cn |
pair_32241054 | Endoscopic surgery is a major achievement in breast surgery during the past 20 years. It is a long process of introduction, inheritance, innovation and development. Endoscopic surgery overcomes the technical bottleneck that how to apply endoscopic surgery in organs without cavities, and improves surgical safety in an a... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 腔镜手术是近20年来乳腺外科技术的重大发展,经历了引进、继承、创新和发展的过程,克服了在无腔隙器官进行腔镜手术的技术瓶颈,从学术和技术上解决了手术安全性等问题。与外科的其他学科相比,乳腺腔镜手术在临床上发展和普及很不平衡,为规范乳腺癌腔镜手术的临床应用,中华医学会外科学分会乳腺外科学组组织专家进行了深入的讨论,重申乳腺癌腔镜治疗的适应证及禁忌证,并针对操作技术的临床操作规范提出具体建议。. | zh-cn |
pair_32241055 | In order to promote the development of infusion therapy in China, to facilitate the scientific research in the field of central venous access device, to provide safe, reasonable and effective central venous catheter for patients, according to the principle of evidence-based medicine, based on the best evidence at prese... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 为推动我国静脉治疗事业的发展,为患者提供安全、合理、有效的中心静脉血管通路装置,促进该领域的科学研究,国内相关领域专家按照循证医学原则,以当前最佳证据为依据,按照问题和推荐强度分级系统,在多学科专家、各级医院的临床医师和护理人员中广泛征求意见,达成本共识。本共识旨在制定中心静脉血管通路装置安全管理的解决方案,并为临床决策提供依据。. | zh-cn |
pair_32241057 | Hepatitis B is a common and multiplex disease in China. Recently, epidemiological studies have shown that hepatitis B virus(HBV) infection is a high-risk factor for the development of intrahepatic cholangiocarcinoma(ICC). Based on a retrospective analysis of relevant literature of recent years, this article concludes t... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 近年来流行病学资料表明,乙肝病毒(HBV)感染是肝内胆管癌(ICC)发生发展的重要危险因素。相关文献的回顾分析结果显示,HBV相关性ICC与其他危险因素引起的ICC在临床病理学特征及治疗方面有很大差异,HBV相关性ICC患者发病年龄较轻、男性发病率高、甲胎蛋白水平较高、CA19-9水平较低、肝硬化明显而淋巴结转移率低,预后较好。这些临床病理学特征与HBV相关性肝细胞癌(HCC)具有相似性,推测可能是因为HBV相关性ICC和HBV相关性HCC的细胞起源一致。对于HBV相关性ICC的治疗,应进行以外科手术为主的综合治疗,以期达到改善预后的效果。. | zh-cn |
pair_32241058 | For patients with hilar cholangiocarcinoma, surgical resection is their only chance of cure. However, the overall prognosis remains dismal. Inrecent years, the clinical cognition, diagnosis and treatment strategies of hilar cholangiocarcinoma have made great progress. Still, a series of controversies remain unresolved ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 目前,外科手术是唯一可能治愈肝门部胆管癌的手段,但其疗效尚无法令人满意,患者预后整体不佳。近年来,肝门部胆管癌的临床认知、诊断及治疗策略已有长足进步,但仍存在许多争议和焦点问题,且在临床指南中缺乏基于高级别循证医学证据的统一意见。这些问题不仅关乎手术的合理选择与患者预后,也是目前开展多中心研究异质性的主要来源。本文对相关问题进行梳理和探讨,希望为未来相关的临床研究提供思路。. | zh-cn |
pair_32241059 | Intrahepatic cholangiocarcinoma(ICC) is the second most common primary liver cancer. The incidence of ICC has been significantly increased globally in recent years. The concealed onset of ICC usually results in late disease diagnosis. Liver resection is currently the only well-established treatment for ICC that may cur... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 肝内胆管癌(ICC)是发病率居第2位的原发性肝癌,近年来该病的发病率上升。ICC通常起病隐匿,导致确诊较晚。目前肝切除是ICC唯一被证实有效的根治性治疗措施,但切除率低,远期疗效不理想。局部治疗联合系统性化疗是目前晚期或不可切除ICC的主要治疗方法,但效果较差。随着对ICC基因表达谱研究的深入及二代测序技术的进展,多个异常信号转导通路(RAS/MAPK、MET、EGFR)及基因突变(FGFR2、IDH1/2)等潜在治疗靶点相继被发现。虽然目前尚无针对ICC的靶向药物获得批准使用,但已有百余项应用范围包括ICC的靶向药物单用或联合化疗的临床试验,部分显示良好的应用前景。随着ICC分子分型研究的进展,个体化的靶向治疗可能是ICC新的治疗... | zh-cn |
pair_32241072 | Severe acute respiratory syndrome (SARS) and coronavirus disease 2019 (COVID-19) shared similar pathogenetic, clinical and pathological features. Fever and cough were the most common symptoms of both diseases, while myalgia and diarrhea were less common in patients with COVID-19. Acute respiratory distress syndrome (AR... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 新型冠状病毒肺炎(COVID-19)与严重急性呼吸综合征(severe acute respiratory syndrome,SARS)在病原体、临床表现、影像学等多方面存在一定的相似性。两种疾病死亡患者的病理表现也存在相似性。SARS及COVID-19的死亡患者病理均表现为弥漫性肺泡损伤(diffuse alveolar damage, DAD)。SARS患者DAD分期与病程有关,病程≤10~14 d为渗出期,病程>10~14 d为增生期,但渗出及增生、纤维化病变常同时出现,部分表现为急性纤维素性机化性肺炎。肺组织内病毒主要位于肺泡上皮细胞,SARS冠状病毒在体内可存在较长时间。两种疾病均有脾、淋巴结、小血管、心脏、肝、肾等多器官... | zh-cn |
pair_32242949 | Parenting very young children in the context of military service, deployment separations, and war-related trauma can be challenging for many families. Female active duty personnel represent one of the fastest growing segments of the military, and recent policy changes have led women to pursue serving in combat position... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 在服兵役、部署分离和有战争创伤的背景下养育非常年幼的儿童对许多家庭来说是一项挑战。女性现役人员是军队中增长最快的部分之一, 最近的政策变化导致女性在战斗岗位上服役的比例更高。虽然对军人母亲的了解不多, 但一些研究表明, 她们在部署周期中会出现明显的痛苦、抑郁和焦虑症状, 在重返社会时会感到与家庭脱节, 子女创伤史的发生率高于男性军人。经历过部署分离、战斗暴露和不良童年经历 (三重威胁) 等综合压力源的军人母亲, 可能面临严重的创伤后压力和抑郁症状的风险, 这可能会对养育、亲子关系的质量和性质产生负面影响。本病例报告描述了一位年轻的单身军人母亲和她的学龄前女儿参加的一项家庭为本的重返社会方案, 该方案是为有年幼儿童 (0-5岁) 的军... | zh-cn |
pair_32242949 | Parenting very young children in the context of military service, deployment separations, and war-related trauma can be challenging for many families. Female active duty personnel represent one of the fastest growing segments of the military, and recent policy changes have led women to pursue serving in combat position... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Le parentage de très jeunes enfants dans le contexte du service militaire, des séparations de déploiement et du trauma lié à la guerre peut s'avérer difficile pour bien des familles. Les femmes des forces armées représentent l'une des segments à la croissance la plus rapide des forces armées américaines et des changeme... | fr |
pair_32242949 | Parenting very young children in the context of military service, deployment separations, and war-related trauma can be challenging for many families. Female active duty personnel represent one of the fastest growing segments of the military, and recent policy changes have led women to pursue serving in combat position... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Die Erziehung von sehr jungen Kindern im Kontext von Militärdienst, einsatzbedingten Trennungen und Kriegstraumata stellt für viele Familien eine Herausforderung dar. Weibliches Personal im aktiven Dienst ist eines der am schnellsten wachsenden Segmente des Militärs. Jüngste politischen Veränderungen haben außerdem daz... | de |
pair_32242949 | Parenting very young children in the context of military service, deployment separations, and war-related trauma can be challenging for many families. Female active duty personnel represent one of the fastest growing segments of the military, and recent policy changes have led women to pursue serving in combat position... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Criar a niños muy pequeños en el contexto del servicio militar, las separaciones debido a asignaciones militares de trabajo y el trauma relacionado con la guerra pueden representar un reto para muchas familias. Las mujeres, como miembros del personal activo con asignaciones militares, representan uno de los segmentos q... | es |
pair_32242968 | To report the Card Games approach used to study men's talk about their risk for prostate cancer and as a method of data collection to analyse patterns of talk among distinct cultural groups. A constructivist grounded theory approach using focus groups to analyse men's social talk about prostate cancer. Data were collec... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 目的: 报告使用纸牌游戏研究男性前列腺癌风险的话题,并作为一种数据收集方法,分析不同文化群体之间的谈话模式。 设计: 以构成主义实地理论方法,使用焦点小组分析男性前列腺癌的社会话题。 方法: 采用非洲加勒比黑人、索马里和英国白人男性三个焦点组收集数据。由一名焦点小组主持人和观察员在选定男性的地区进行焦点小组。为鼓励人们交谈,给他们四种游戏的纸牌。 结果: 非洲裔加勒比男性以同意和不同意的方式开展谈论,最为民主;索马里男性的谈话最包容和最幽默。英国白人男性的谈话中充满竞争意味,对彼此的观点最不包容。 结论: 纸牌游戏揭示了谈话模式的差异,为了解男性如何利用社交谈话来提高对前列腺癌风险的认识提供依据。这对医疗护理人员很有用,其为与男性展... | zh-cn |
pair_32242974 | To investigate the relationships between spirituality, somatic symptom distress/severity, depressive symptoms and quality of life (QOL) for adolescents diagnosed with spina bifida (SB). Exploratory, cross-sectional design. Fifty-eight adolescents with SB in southern California were recruited during routine visits to a ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 目的: 探讨脊柱裂(SB)青少年的精神状态、身体症状痛苦/严重性、抑郁症状与生活质量(QOL)的关系。 设计: 探索性的横断式设计。 方法: 从2016年1月至2017年1月,招募58名患有脊柱裂的青少年前往南加州某医科大学的多学科诊所进行定期随访。每个青少年都完成了一系列自陈式测量,包括信念系统调查表、身体症状量表、患者健康问卷和儿科生活质量调查表。并采用通径分析检查每种直接和间接影响的回归系数。 结果: 中介-调节分析显示,抑郁症状对于抑郁症状与生活质量的关系起到完全的中介作用(B = 0.029 [0.014],CI [0.007, 0.061]),精神状态的程度越高,对于抑郁症状与生活质量的关系越有调节作用(B = 0.05... | zh-cn |
pair_32246528 | Currently, type 1 diabetes requires lifelong insulin injection and careful blood glucose control to prevent secondary complications, but islet transplantation could make a type 1 diabetic patient insulin independent. On the other hand, islet transplantation needs human donors and donor shortage is the most serious issu... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 目前, 1型糖尿病患者需要终生注射胰岛素并仔细控制血糖以预防继发的并发症, 但胰岛移植可以使1型糖尿病患者不再依赖胰岛素注射。但另一方面, 胰岛移植需要人类供体, 供体短缺是最严重的问题。为了缓解供体短缺, 无心跳的活体供体也会被采用。此外, 胰岛分离和移植的效果也已提高, 然而, 只要人类捐赠者是唯一的来源, 供体短缺的问题就不会得到解决。 为了解决供体短缺的问题, 1994年开始使用猪胰岛进行异种胰岛移植。异种胰岛移植具有治愈许多1型糖尿病患者的潜力, 尽管存在发生严重或新型感染的风险。因此, 世界卫生组织对异种移植很感兴趣, 国际异种移植协会(International Xenotransplantation Associat... | zh-cn |
pair_32249482 | Cutaneous vascular malformations (CVM) represent a spectrum of human diseases identified at birth or in paediatric patients and classified according to the type of vessel affected. Confusing classification in human medicine has led to misdiagnoses and frequent nomenclature revision. Cutaneous lymphatic malformations (C... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 背景: 皮肤血管畸形(CVM)是人类在出生或童年时罹患的一类疾病,需要根据发病血管的类型进行分类。人医的分类混乱常导致误诊和频繁的命名修订。皮肤淋巴管畸形(CLM)在人医中鲜有报道。 目的: 报告2只猫真皮浅层皮肤淋巴管畸形(SDCLM)的临床病理表现。 动物: 两只不相关的成年家养短毛猫。 方法: 对两只猫进行临床评价,并在出生后用皮肤镜分别评价是否出现复发性肿胀,以及右后足和左后足是否存在囊泡渗出浆液血性液体。收集皮肤活检样本,进行组织病理学和免疫组化评估及电镜观察。 结果: 根据发病年龄、临床体征、诊断性影像学结果和组织病理学结果,怀疑为CVM。皮肤镜用于描述皮肤表面的变化。免疫组化结果和电镜证实了淋巴管发病。 结论和临床重要... | zh-cn |
pair_32249482 | Cutaneous vascular malformations (CVM) represent a spectrum of human diseases identified at birth or in paediatric patients and classified according to the type of vessel affected. Confusing classification in human medicine has led to misdiagnoses and frequent nomenclature revision. Cutaneous lymphatic malformations (C... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Les malformations vasculaires cutanées (CVM) représentent un spectre de maladies humaines identifiées à la naissance ou chez les enfants et sont classés selon le type de vaisseaux atteints. Une classification trouble en médecine humaine a mené à des erreurs de diagnostic et de fréquentes révisions de nomenclature. Les ... | fr |
pair_32249482 | Cutaneous vascular malformations (CVM) represent a spectrum of human diseases identified at birth or in paediatric patients and classified according to the type of vessel affected. Confusing classification in human medicine has led to misdiagnoses and frequent nomenclature revision. Cutaneous lymphatic malformations (C... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Kutane Blutgefäßmissbildungen (CVM) repräsentieren ein Spektrum an Erkrankungen des Menschen, die bei der Geburt oder bei Pädiatriepatienten identifiziert und nach dem betroffenen Blutgefäßtyp eingeteilt werden. Eine verwirrende Einteilung in der Humanmedizin hat zu falschen Diagnosen und häufiger Revision der Nomenkla... | de |
pair_32249482 | Cutaneous vascular malformations (CVM) represent a spectrum of human diseases identified at birth or in paediatric patients and classified according to the type of vessel affected. Confusing classification in human medicine has led to misdiagnoses and frequent nomenclature revision. Cutaneous lymphatic malformations (C... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | As malformações vasculares cutâneas (CVM) representam um espectro de doenças humanas identificadas ao nascimento ou em pacientes pediátricos e são classificadas de acordo com o tipo de vaso afetado. A classificação confusa em medicina humana levou a diagnósticos errôneos e frequente revisão de nomenclatura. Malformaçõe... | pt |
pair_32249482 | Cutaneous vascular malformations (CVM) represent a spectrum of human diseases identified at birth or in paediatric patients and classified according to the type of vessel affected. Confusing classification in human medicine has led to misdiagnoses and frequent nomenclature revision. Cutaneous lymphatic malformations (C... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | las malformaciones vasculares cutáneas (CVM) representan un espectro de enfermedades humanas identificadas al nacer o en pacientes pediátricos y clasificadas según el tipo de vaso afectado. La clasificación confusa en medicina humana ha llevado a diagnósticos erróneos y una revisión frecuente de la nomenclatura. Las ma... | es |
pair_32249514 | Cutaneous histiocytomas (CH) are derived from epidermal Langerhans cells. Single CH are generally associated with a good prognosis in dogs because most undergo spontaneous remission. However, aggressive behaviour and lymph node metastasis have been reported in a small number of dogs with single CH. To describe the clin... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 背景: 皮肤组织细胞瘤 (CH) 来源于表皮郎格罕细胞。因为犬的单个CH大多数能自愈,所以通常预后良好。然而,在少数单个 CH患犬的病例报告中,发现了侵袭行为和淋巴结转移。 目的: 描述位于犬耳道的侵袭性CH的临床表现、治疗和发病过程。 动物: 8 岁、未去势雄性罗威纳犬。 方法和材料: 在常规苏木精和伊红染色样本中,单侧耳道肿块被确定为 CH。通过证明郎格罕细胞标记物(Iba-1、E-cadherin 和 CD18)以及缺乏 B 细胞 (CD79a、CD20、Pax5)、T 细胞 (CD3)、浆细胞 (Mum-1) 和巨噬细胞 (CD11d、CD204) 标记物来确诊。 结果: 进行全耳道切除,但肿瘤细胞延伸至整个水平耳道和深部手... | zh-cn |
pair_32249514 | Cutaneous histiocytomas (CH) are derived from epidermal Langerhans cells. Single CH are generally associated with a good prognosis in dogs because most undergo spontaneous remission. However, aggressive behaviour and lymph node metastasis have been reported in a small number of dogs with single CH. To describe the clin... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Les histiocytomes cutanés (CH) sont issus des cellules de Langerhans épidermiques. Un CH unique est généralement de bon pronostic chez le chien, la majorité rétrocédant spontanément. Cependant, une évolution agressive et des métastases ganglionnaires ont été décrites dans un faible nombre de cas de CH unique. Décrire l... | fr |
pair_32249514 | Cutaneous histiocytomas (CH) are derived from epidermal Langerhans cells. Single CH are generally associated with a good prognosis in dogs because most undergo spontaneous remission. However, aggressive behaviour and lymph node metastasis have been reported in a small number of dogs with single CH. To describe the clin... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Kutane Histiozytome (CH) entspringen den epidermalen Langerhans Zellen. Einzelne CH werden generell mit einer guten Prognose bei Hunden gesehen, weil die meisten eine spontane Remission durchlaufen. Es wurde jedoch auch aggressives Wachstum und Lymphknotenmetastasierung in einer geringen Anzahl von Hunden mit einzelnen... | de |
pair_32249514 | Cutaneous histiocytomas (CH) are derived from epidermal Langerhans cells. Single CH are generally associated with a good prognosis in dogs because most undergo spontaneous remission. However, aggressive behaviour and lymph node metastasis have been reported in a small number of dogs with single CH. To describe the clin... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Os histiocitomas cutâneos (HC) são derivados de células de Langerhan epidérmicas. O HC único está geralmente associado a um bom prognóstico em cães, porque a maioria sofre remissão espontânea. No entanto, comportamento agressivo e metástase para linfonodos foram relatados em um pequeno número de cães com HC único. Desc... | pt |
pair_32249514 | Cutaneous histiocytomas (CH) are derived from epidermal Langerhans cells. Single CH are generally associated with a good prognosis in dogs because most undergo spontaneous remission. However, aggressive behaviour and lymph node metastasis have been reported in a small number of dogs with single CH. To describe the clin... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | los histiocitomas cutáneos (CH) se derivan de las células epidérmicas de Langerhans. Los CH únicos generalmente se asocian con un buen pronóstico en los perros porque la mayoría experimenta una remisión espontánea. Sin embargo, se ha reportado un comportamiento agresivo y metástasis en ganglios linfáticos en un pequeño... | es |
pair_32250016 | Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy. Left untreated or poorly controlled, GDM results in adverse infant outcomes such as large for gestational age (LGA). This study aims to identify nonglycemic maternal and fetal factors predictive of LGA outcomes in pregnancies comp... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 背景: 妊娠糖尿病(GDM)是妊娠期最常见的并发症之一。如果不进行治疗或控制不佳, GDM会导致不良的婴儿结局, 如大于胎龄儿(LGA)。这项研究旨在确定饮食管理的GDM, 其LGA结局的非血糖母婴因素。 方法: 这是一项回顾性队列研究,追踪了从2004年到2015年单胎妊娠并进行饮食管理的GDM患者。对产妇和产期因素进行多因素Logistic回归分析, 找出LGA的危险因素。此外, 对妊娠18周到22周、24周到28周和29周到33周有胎儿腹围的超声测量数据进行了亚组单变量分析。 结果: 共纳入1064名妇女, 分娩123名LGA婴儿。产次高(比值比(OR)1.44;CI, 1.23-1.68;P<0.001)和孕前体重指数(BM... | zh-cn |
pair_32250018 | Partial remission (PR) is a special stage in type 1 diabetes (T1D). The different patterns of PR frequency, characteristics, and determinants in juvenile and adult patients are unclear, and data on Chinese are lacking. A total of 186 children and 114 adults with T1D who were regularly followed up in a cohort were inclu... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 背景: 蜜月期(partial remission, PR)是1型糖尿病(type 1 diabetes, T1D)病程中胰岛功能短暂恢复的特殊时期。PR的发生率、临床特征及影响因素等尚缺乏中国人群的研究数据, 且儿童及青少年患者与成人患者间PR发生情况的差异尚未明确。 方法: 本研究从一个自身免疫性糖尿病随访队列中, 共纳入186名儿童及青少年T1D患者及114名成人T1D患者。PR的定义为:1)C-肽≥300pmol/L; 或2)胰岛素校正糖化血红蛋白指数≤9。采用化学发光法检测C-肽, 采用国际标准放射配体法检测胰岛自身抗体。 结果: 与成人患者相比, 儿童及青少年患者PR的发生率较高(69.9% 对 58.8%, P<0.0... | zh-cn |
pair_32250076 | Objective To analyze the differences among electrical damage, burns and abrasions in pig skin using Fourier transform infrared microspectroscopy (FTIR-MSP) combined with machine learning algorithm, to construct three kinds of skin injury determination models and select characteristic markers of electric injuries, in or... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 傅里叶变换显微红外光谱结合机器学习算法鉴定电击伤. 目的 基于傅里叶变换显微红外光谱结合机器学习算法分析猪皮肤电击伤、烧伤及擦伤的差异,构建3种皮肤损伤鉴定模型,筛选电击伤特征性标志物,为皮肤电流斑鉴定提供新方法。 方法 建立猪皮肤电击伤、烧伤及擦伤的模型,使用传统HE染色检验不同损伤的形态学改变。运用傅里叶变换显微红外技术检测表皮细胞光谱,运用主成分、偏最小二乘法分析损伤的分类情况,运用线性判别和支持向量机构建分类模型,因子载荷筛选特征性标志物。 结果 与对照组相比,电击伤、烧伤及擦伤组的表皮细胞均呈现出极化现象,以电击伤、烧伤组更为明显。通过主成分和偏最小二乘法分析可区分不同类型损伤,线性判别、支持向量机模型均能够有效诊断不同损... | zh-cn |
pair_32250077 | Objective To establish a qualitative and quantitative method to determine ammonia in biological samples by gas chromatography-mass spectrometry (GC-MS). Methods A heptafluorobutyryl chloride derivatization method was used. GC-MS was used for determination. The effects of different pH conditions, derivatization temperat... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | GC-MS衍生化方法快速检测生物样品中的氨. 目的 建立生物样品中氨的气质联用定性和定量检测方法。 方法 采用七氟丁酰氯衍生化,气相色谱-质谱联用仪(gas chromatography-mass spectrometry,GC-MS)检测。考察不同pH值条件、衍生化温度、时间和不同提取溶剂对检测结果的影响,优化前处理条件。 结果 该方法能够准确检测血浆中氨的含量,检出限为0.1 μg/mL,目标物在0.5~200.0 μg/mL范围内线性关系良好(<i>R</i><sup>2</sup>=0.987 7),日内精密度相对标准偏差范围为2.59%~3.88%,日间精密度相对标准偏差范围是3.21%~3.76%。 结论 该方法具有良好... | zh-cn |
pair_32250078 | Objective To establish an analysis method for simultaneous determination of 13 sedative substances and their metabolites in blood by liquid-liquid extraction and liquid chromatography-tandem mass spectrometry (LC-MS/MS) technology and to apply the method to actual cases. Methods The samples were extracted with ethyl ac... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | LC-MS/MS快速测定血液中13种安眠镇静类药物及其代谢产物. 目的 采用液液提取与液相色谱-串联质谱(liquid chromatography-tandem mass spectrometry,LC-MS/MS)技术,建立同时测定血液中13种安眠镇静类药物及其代谢产物的分析方法,并将其应用于实际案例。 方法 血液加入内标后,用乙酸乙酯提取,浓缩至近干后,用甲醇溶解残渣,过0.22 μm滤膜后测定。13种安眠镇静类药物及其代谢物经C<sub>18</sub>色谱柱分离,以甲醇和20 mmol/L甲酸铵(含0.1%甲酸)水溶液进行梯度洗脱,电喷雾正离子模式检测,内标法定量。 结果 血液中13种安眠镇静类药物及其代谢物在5~200 ... | zh-cn |
pair_32250079 | Objective To discuss the activation characteristics of the prefrontal cortex of people with mild cognitive impairment (MCI) due to brain trauma during working memory tasks. Methods The psychological experiment design software E-prime was used and N-back paradigm was adopted as working memory task. Functional near-infra... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 基于fNIRS技术检测脑外伤所致轻度认知功能障碍者工作记忆. 目的 探讨脑外伤所致轻度认知功能障碍者在执行工作记忆任务中前额叶皮质的激活特点。 方法 利用E-prime心理实验设计软件,采用N-back范式作为工作记忆的任务,应用功能性近红外光谱成像(functional near-infrared spectroscopy,fNIRS)技术检测24名脑外伤所致轻度认知功能障碍者(研究组)和年龄、性别相匹配的27名健康正常志愿者(对照组)前额叶22个通道的皮质氧合血红蛋白(oxyhemoglobin,HbO)浓度的变化,同步记录按键错误个数和反应时间等行为学数据。采用独立样本t检验、非参数检验等对各个任务下两组HbO浓度变化平均值和... | zh-cn |
pair_32250080 | Objective To retrospectively analyze 40 cases of hanging and 33 cases of ligature strangulation in Kunming, to explore the neck injury characteristics and similarities and differences of related asphyxia signs of corpses in hanging and ligature strangulation cases, in order to provide reference for forensic identificat... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 73例缢死及勒死案例的回顾性分析. 目的 对昆明市40例缢死及33例勒死案例进行回顾性分析,主要研究缢死及勒死尸体的颈部损伤特征、相关窒息征象的异同,以期为法医学鉴定提供参考。 方法 收集昆明市公安局2000—2017年受理的缢死及勒死案例资料,对缢死及勒死的死者性别、年龄、致伤工具、颈部损伤、相关窒息征象的数据经SPSS 23.0进行统计检验。 结果 男性缢死者多于女性,女性勒死者多于男性,缢死者平均年龄大于勒死者。缢死自杀多见,他杀罕见;勒死他杀多见,自杀或意外少见。缢沟多位于甲状软骨上方,勒沟多位于甲状软骨水平。索沟处表皮剥脱或皮下出血是最常见的生活反应,在缢死者中常见。勒死者舌骨骨折率高于缢死者。 结论 死者性别及年龄分布、... | zh-cn |
pair_32250081 | Objective To discuss the types, number and diagnostic methods of traumatic tooth fracture in order to provide reference for forensic clinical identification. Methods The 41 cases accepted by Judicial Appraisal Center of Gansu University of Political Science and Law from January 2015 to December 2017, were analyzed by d... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 41例外伤性牙折的法医学鉴定分析. 目的 讨论外伤性牙折的种类、数量及确诊方法,为法医临床学鉴定提供参考。 方法 对甘肃政法大学司法鉴定中心2015年1月至2017年12月受理的41例因外伤致牙折的实际案例,按照基本情况、致伤方式、牙折类型及数量、确诊方法、鉴定意见等信息进行描述性统计。 结果 41例案例中,男性31例,女性10例,上颌前牙最常发生牙折,碰撞伤是外伤性牙折的主要致伤方式,CT检查可提高鉴定的准确性。 结论 牙折案例存在性别差异,牙折部位与牙齿的解剖学特点有关,牙折案例可优先选择CT检查,外伤性牙折的法医学鉴定需综合分析牙折类型及数量,明确外伤与牙折的关系。. 法医学;创伤和损伤;牙折断;案例分析. | zh-cn |
pair_32250082 | Objective To discuss the application of 3D laser scanner and computer technology in restoration of the accident scene and reconstruction of the accident process, as well as identification of the driver-passenger relationship. Methods The scene of a traffic accident, the accident vehicle and the vehicle of the same type... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 利用三维激光扫描技术还原事故过程及驾乘关系分析. 目的 探讨三维激光扫描仪和计算机技术在还原事故现场、事故过程重建及驾乘关系鉴定中的应用。 方法 运用三维激光扫描仪对一起交通事故现场、事故车辆及与事故车辆同型号车进行扫描,计算机技术对事故现场、痕迹及事故车辆进行整合,还原事故现场,结合人体损伤,重建并分析事故过程。 结果 经三维激光扫描仪还原事故现场及重建事故过程,明确事发时吴某位于驾驶位。 结论 利用三维激光扫描技术还原事故现场、事故过程重建、分析车内人员运动轨迹更客观、科学,有助于提高道路交通事故司法鉴定的精度。. 法医病理学;事故,交通;三维激光扫描;驾乘关系;现场还原;事故重建. | zh-cn |
pair_32250083 | Objective To discuss the application value of CT scanning technology in cause of death determination of medical dispute cases. Methods From July 2017 to December 2018, postmortem CT imaging data of 12 medical dispute cases were collected. CT imaging diagnosis results and anatomy findings as well as differences between ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 虚拟解剖技术在医疗纠纷尸体检验中的应用. 目的 探讨CT扫描技术在医疗纠纷死亡原因鉴定中的应用价值。 方法 在2017年7月至2018年12月间,对12例医疗纠纷案例行全身CT检验,比较CT影像诊断与解剖所见及生前与死后CT诊断的差异性,分析尸体的CT常规检验在病变与损伤的诊断方面的优势与劣势。 结果 CT影像诊断与解剖所见比较显示,在密度改变差异大的病变和损伤的诊断方面CT检验存在优势,如肺不张、肺炎、钙化、骨折、出血等;生前与死后CT诊断的比较显示医疗纠纷案件的尸体保存都较为良好,死后CT扫描检验对生前疾病诊断具有意义。 结论 虚拟解剖技术在医疗纠纷尸体检验中有较高的应用价值,可在尸体解剖前为鉴定人提供有效信息,也可在无法进行解... | zh-cn |
pair_32250084 | Traditional forensic identification relies on forensic experts to manually extract information and provide identification opinions based on medicine, biology and other fields of knowledge combined with personal work experience, which is not only time-consuming and require great effort, but also affected by subjective f... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 人工智能技术时代法医学科面临的新机遇与挑战. 传统的法医学鉴定依赖于法医专家提取信息,运用医学、生物学等多领域知识结合工作经验作出鉴定意见,不仅耗时耗力,而且存在难以克服的主观因素。在大数据时代,人工智能的蓬勃发展为法医学带来了新思路。近些年,国内外法医学者们基于人工智能技术开展了人脸识别、年龄及性别鉴定、DNA分析、死亡时间推断、损伤以及死亡原因鉴定等多方面的研究,显示出运用人工智能技术解决法医学鉴定问题的可行性与优越性。人工智能技术作为一种适应时代发展的崭新技术手段,为法医学带来新活力的同时,也带来了新挑战。如何科学应对这些挑战,形成人工智能和法医学协同发展的“人工智能+法医学”新模式,是大数据时代下法医学发展的新方向。. 法医... | zh-cn |
pair_32250085 | The estimation of postmortem interval (PMI) is a core issue in forensic practice. A large amount of time-dependent data can be produced in the decomposition process of a body, however, such multidimensional data cannot be comprehensively and effectively analyzed and utilized by any existing conventional PMI estimation ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 大数据与人工智能:死后间隔时间推断的新视野. 死后间隔时间(postmortem interval,PMI)推断是法医学实践的核心问题之一。尸体腐败过程可产生大量时间依赖性参数,而现有的任一传统PMI推断方法均无法实现对此类多维度数据全面有效的分析和利用。作为近年来快速发展的信息技术,人工智能(artificial intelligence,AI)在大数据处理方面具有综合、高效、自动化的显著优势,部分学者已将其引入PMI推断研究,展现了其明显优于传统方法的准确性和发展前景。本文将对大数据及AI在PMI推断中应用的意义、模式及研究成果进行综述,并对后续研究提出建议与展望。. 法医病理学;人工智能;死亡时间推断;综述. | zh-cn |
pair_32250086 | Bone age assessment has always been one of the key issues and difficulties in forensic science. With the gradual development of machine learning in many industries, it has been widely introduced to imageology, genomics, oncology, pathology, surgery and other medical research fields in recent years. The reason why the a... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 机器学习在骨龄评估中的研究进展及展望. 骨龄评估一直是法医学研究领域的重点及难点问题之一。近年来,随着机器学习在诸多行业内的逐渐兴起,其已被广泛引入影像学、基因组学、肿瘤学、病理学以及外科学等医学研究领域中。上述研究领域之所以能与机器学习紧密结合,主要是由于上述医学分支学科中的研究对象属于计算机视觉范畴,而机器学习对于计算机视觉研究有着得天独厚的优势,并在医学图像识别中取得突破性进展。基于机器学习在图像识别中的优势,将其与骨龄评估研究有机结合,旨在为构建适用于法医学骨骼影像图片的识别模型。基于此,本文将对近年来国内外学者运用机器学习技术在骨龄评估中的研究进展进行综述。. 法医人类学;年龄测定,骨骼;机器学习;综述. | zh-cn |
pair_32250087 | The number of death from insulin overdose, including accidental poisoning, suicide and homicide, is increasing these years. The forensic diagnosis of death from insulin overdose is a tough task. Glucose is the main energy source of the brain. Therefore, hypoglycemic brain damage is considered to be the main reason of d... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 胰岛素过量致低血糖脑损伤神经病理学研究进展. 胰岛素意外中毒、自杀,甚至他杀致死案件日趋增多,而胰岛素过量致死的法医学诊断极为困难。葡萄糖是大脑最主要的能量来源,因此低血糖脑损伤被认为是胰岛素过量致死的主要原因。近年来,胰岛素过量致低血糖脑损伤的研究逐渐在法医学领域受到重视,本文从法医神经病理学的角度,综述胰岛素过量致低血糖脑损伤的神经病理学改变、病理生理过程及潜在神经分子标志物,为法医学相关领域的科研及实践提供借鉴。. 法医病理学;胰岛素;脑损伤;低血糖症;综述. | zh-cn |
pair_32250088 | In recent years, cases of child abuse that result in injuries and death have occurred from time to time in China, and there may be more undetected child abuse cases. However, many pediatricians and forensic doctors lack professional knowledge and formal training in detecting child abuse, which leads to the missed diagn... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 虐待儿童致皮肤损伤及骨折的法医学意义. 近年来,我国虐待儿童致伤、致死的案件时有发生,未被发现的虐待儿童案件可能更多。而许多儿科医生和法医都缺乏虐待儿童方面的专业知识及正规培训,导致许多虐待儿童案件被漏诊、误诊及错误鉴定的发生。本文复习了国内外相关文献,结合实际工作经验及我国国情,初步总结出关于虐待儿童案件的临床诊断及法医学鉴定要点,以期为虐待儿童案件的早期发现、准确鉴定及受虐儿童得到及时有效的治疗保护提供一些帮助。. 法医学;虐待儿童;创伤和损伤;皮肤;骨折;综述. | zh-cn |
pair_32250089 | In forensic science practice, age is an important individual information, and one of the indicators to be considered first to depict features of the suspect. Recently, DNA methylation has become a research hotspot in age estimation because of its hig accuracy and stability. New progress has been made in specificity of ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | DNA甲基化推断人类年龄的研究进展. 在法庭科学实践中,年龄是重要的个体信息,是刻画嫌疑人特征首先要考虑的指标之一。近年来,DNA甲基化因其出色的准确性和稳定性成为年龄推断的研究热点。在DNA甲基化位点的特异性、跨组织年龄推断、未成年人的DNA甲基化年龄推断、年龄推断的灵敏度和法医学实际应用等方面均取得了新进展。同时,一些研究建立了更精确的统计建模方法、消除不同检测平台的差异、找寻模型中合适的位点数量、分析了环境和疾病的影响,本文对此进行综述以提供参考。. 法医遗传学;DNA甲基化;年龄测定;综述. | zh-cn |
pair_32250090 | Aconitum is one of the most widely used Chinese herbal medicines, and aconitine is the major toxic component in it. Aconitine can induce a variety of arrhythmias, resulting in death. Acute ethanol consumption causes arrhythmia as well. Poisoning cases caused by aconitum medicinal liquor are frequently encountered in th... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 乙醇-乌头碱致心律失常的毒理分子机制研究进展. 乌头属植物是广泛使用的中草药代表之一,乌头碱是其中最主要的毒性成分,主要引起多种心律失常而致死。急性乙醇摄入也可引起心律失常。法医学实践中常遇到乌头类药酒引起的中毒案例。这两者的心肌毒性分子机制有较多共通点,均对心肌细胞膜钠通道、钙通道及钾通道等产生影响。本文通过综述近年来乙醇、乌头碱心脏毒性机制的研究报道,分析讨论乙醇-乌头碱可能共同影响的心肌细胞通道蛋白,为联合中毒致心律失常的分子机制研究提供思路与参考。. 法医毒理学;中毒;乙醇;乌头碱;心律失常;综述. | zh-cn |
pair_32252194 | Breast cancer is the most common malignant tumor among women. Taxanes are one of the most frequently used chemotherapy regimens for breast cancer. In order to guide clinicians rational use of taxanes and further standardize the diagnosis and treatment of breast cancer, the expert group proposed this 'Expert consensus o... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 乳腺癌是女性最常见的恶性肿瘤,严重威胁女性健康。紫杉类药物是乳腺癌治疗中最常用的药物之一。乳腺癌中紫杉类药物临床应用专家共识专家委员会基于循证医学证据的进展,深入探讨了乳腺癌中紫杉类药物的临床应用,形成了乳腺癌中紫杉类药物临床应用专家共识,以期指导临床医师合理用药,进一步规范诊疗行为。. | zh-cn |
pair_32252195 | Taxanes are cornerstones of cancer chemotherapy and can be used for the treatment of various tumors, including breast cancer. Taxane-associated peripheral neuropathy is a common adverse effect of taxanes, leading to discontinuation of drug therapy, affecting drug treatment outcomes, and severely affecting patients' qua... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 紫杉类药物是肿瘤化学治疗的基石药物,可用于包括乳腺癌在内的多种肿瘤的治疗。紫杉类药物相关周围神经病变是紫杉类药物的常见不良反应,可导致药物治疗中止,影响药物治疗结局,且严重影响患者的生活质量。《紫杉类药物相关周围神经病变规范化管理专家共识》针对紫杉类药物相关周围神经病变的发病机制、临床特点、相关危险因素、诊断评估、预防和治疗等展开阐述和推荐。希望本共识可规范当前国内紫杉类药物相关周围神经病变的管理,提高临床医师对紫杉类药物相关周围神经病变的认识,从而改善患者的治疗结局,提高患者生活质量。. | zh-cn |
pair_32252196 | Luminal breast cancer is the most common subtype of breast cancer, representing more than 60% of all breast cancers. Endocrine resistance and late recurrence are two challenges in the treatment of luminal breast cancer. To overcome endocrine resistance in multiple levels, high-dose-fulvestrant can inhibit estrogen-rece... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Luminal型乳腺癌是最常见的乳腺癌分型,约占乳腺癌的60%以上,其治疗难点在于内分泌治疗耐药和远期复发。针对内分泌治疗耐药,应根据不同的通路机制从多角度入手,可用高剂量氟维司群抑制雌激素受体通路,或加用各类靶向药物阻断非雌激素受体通路。为降低Luminal型乳腺癌远期复发的风险,则应建立复发预测模型,延长高危复发患者内分泌治疗的时限,加用卵巢去势或血管生成抑制剂。以Luminal型乳腺癌治疗难点指导科学研究,将研究成果回归临床应用,最终优化临床治疗策略。. | zh-cn |
pair_32253890 | Talent training is the core and foundation of public health system construction. Shortage of talents in the field of disease prevention and public health exposed by COVID-19 pandemic highlights the importance of developing preventive medical education. This article analyzes the challenges of medical education in the di... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 人才培养是公共卫生体系建设的核心和基石,新型冠状病毒肺炎疫情暴露出的疾病预防与公共卫生领域人才匮乏问题,更突显了改革发展预防医学教育的重要性。本文分析了“医防分离”现实困境中医学教育面临的挑战,以及健康中国战略下新医科建设对预防医学教育提出的新要求,从加大预防医学教育资源配置和投入力度、培养“顶天立地”的公共卫生专业人才、实施公共卫生核心能力的全体医学生教育、建立健全预防医学继续教育制度等四个方面进行了思考,并提出建立全链条闭环的研究体系支撑公共卫生拔尖创新人才培养、加强临床医学专业执医准入的公共卫生核心能力考核、制定“医防融合”的基层卫生人才培养方案、实施“平战结合”模式下的公共卫生人才预备役制度等一系列具体建议,以期对我国预防医... | zh-cn |
pair_32253891 | As a newly epidemic, 2019 coronavirus disease (COVID-19) with a concentrated outbreak poses a great challenge to medical treatment. The severe and critical patients are complex complicatied with the psychological problems, and the medical staff are overworked and under tremendous psychological pressure. The surgeon par... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 作为新发传染病,集中暴发的新型冠状病毒肺炎(COVID-19)对医疗救治提出很大挑战。尤其是重型及危重型患者病情复杂,合并较多心理问题,而医务人员超负荷工作同时承受巨大心理压力。外科医师参与应急医疗救援,可对患者合并的外科疾病进行专科处理,同时对非外科医师培训COVID-19治疗过程中常见的外科相关问题,降低外科相关病死率。外科医师结合自身特点,扬长补短,利用团队意识佳、无菌观念强及心理素质好的优势,在做好自身防护的前提下快速适应并开展救援工作;同时建立重症管理观念,重点掌握疫情相关重症支持设备,针对疫情特点快速转型。建议结合外科住院医师规范化培训培养复合型外科人才。希望上述思考可以对外科医师更好地参与传染病应急医疗救援及外科教育提... | zh-cn |
pair_31204910 | To explore the clinical features and therapeutic efficacy in adult ALL patients with t (1; 19) (E2A-PBX1). The clinic data of 19 adult ALL patients with t (1; 19) (E2A-PBX1) in our hospital from Nov. 22, 2010 to Apr. 4, 2018 were collected. The clinical features,complete remission (CR) rate, overall survival (OS) rate ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 伴t(1;19)(E2A-PBX1)的成人急性淋巴细胞白血病的临床特点及疗效分析. 探讨伴t(1;19)(E2A-PBX1)成人急性淋巴细胞白血病(ALL)的临床特点及疗效. 收集2010年11月22日至2018年4月11日我中心收治的19例伴t(1;19)(E2A-PBX1)初治ALL患者的临床资料,分析患者的临床资料特点、化疗及化疗+造血干细胞移植的完全缓解率(CR)、总生存(OS)和无复发生存(RFS). 19例患者中位年龄24岁(14-66岁),男女比例为0.73∶1。中位白细胞数16.47×109(1.8-170.34)/L, 中位血红蛋白98(65-176)g/L,中位血小板数50(15-254)×109/L。免疫分型P... | zh-cn |
pair_31204911 | To clone the promoter sequence of acute monocytic leukemia new antigen gene.MLAA-34 and identify its promoter core region. The full-length fragment of MLAA-34 gene promoter region was amplified by PCR, then was ligated into pGL3-Basic vector, and the recombinant plasmid was cloned. Constructed a series of MLAA-34 gene ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 急性单核细胞白血病新抗原基因MLAA-34启动子的克隆及其核心区鉴定. 克隆急性单核细胞白血病新抗原基因MLAA-34上游启动子序列并检测其活性、鉴定核心区域. PCR扩增 MLAA-34基因启动子区全长片段,将其连接至pGL3Basic 载体,克隆重组质粒; 构建一系列 MLAA-34基因启动子 5′侧翼区截短质粒; 将含MLAA-34启动子序列的重组质粒及其截短型质粒转染至U937、HEK293细胞,应用双荧光素酶报告基因检测各片段的启动子活性,确定启动子最小活性区域,并通过生物信息学方法分析转录因子结合位点. 构建了含有MLAA-34启动子序列的重组质粒及其截短型质粒;与空载体相比,其启动子活性明显增加(P<0.001) M... | zh-cn |
pair_31204912 | To investigate the clinical significance of SCIN gene expression and promoter methylation in patients with chronic myeloid leukemia (CML). Real-time quantitative PCR was used to detect the expression level of SCIN in mononucleatr cells of bone marrow samples from 64 CML patients and 37 controls. The methylation levels ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | None | zh-cn |
pair_31204913 | To analyze the 5 experimental indexes of CDSS in the patients with acute leukemia (AL) so as to provide the laboratorial basis for the early diagnosis and treatment of the secondary DIC in AL. Three hundred and thirty three patients with AL were divided into 7 groups, such as AML-M1-M5, other AML and ALL. The experimen... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 333例初诊急性白血病的CDSS实验指标分析. 分析初诊急性白血病(AL)患者的CDSS 5项实验指标,为临床及早诊治AL继发的DIC提供实验室依据。方法:。结果:。结论:。. 将333例AL患者分为AML-M1等(AML-M1-M5,其它AML和ALL)7个组,并以100例健康体检者作为对照组。观察各组的实验指标变化、CDSS评分值并进行两两比较,同时分析所有病例中的早期死亡等临床事件. 5项实验指标中阳性率最高的是血小板(59.76%),其次是D-D(30.93%),而APTT最低(2.70%);与对照组比较,除APTT(AML-M3组)和FIB(其他AML组)外,其余实验指标结果的差异均有非常显著的统计学意义(P<0.01);... | zh-cn |
pair_31204914 | To study the instability of mitochondrial DNA(mt DNA) D-loop region genes in patients with Leukemia. The HV-1 and HV-2 regions of D-loop region in 24 patients with leukemia were amplificated and sequenced, then their results were compared with revised Cambridge reference sequence (rCRS) and Databank mtDB. The mutation ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 白血病患者线粒体基因组D-loop区基因不稳定性研究. 探讨白血病患者线粒体基因组D-loop区基因的不稳定性. 采用 PCR扩增24例患者D-loop区HV-1和HV-2两个高变区并测序,其结果与剑桥标准序列(rCRS)和mtDB数据库进行比对,分析其突变情况。采用SPSS 22.0统计学软件对数据进行分析. 23例患者D-loop区发生突变,突变率95.83%(23/24);共检测到82个基因突变,其中HV-1区47个(57.32%),HV-2区35个(42.68%)。急性髓系白血病患者中未治疗组(UT)与治疗组(T)对比:突变率分别为(2.37±0.82)×10<sup>-3</sup>和(4.76±2.45)×10<sup>... | zh-cn |
pair_31204915 | To investigate the effect of Pim1 expression up-regulation on cell proliferation, apoptosis, chemotaxis and angiogenesis in acute myeloid leukemia (AML) cell line U937, and to explore the possible molecular mechanism involved, finally to estimate the Pim1 expression in primary AML cells. GFP-tagged plasmid for Pim1 ove... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Pim1基因过表达在急性髓系白血病发病机制中的作用研究. 研究Pim1上调对急性髓系白血病(acute myeloid leukemia,AML)细胞系U937增殖、凋亡、趋化作用和血管生成的影响,探讨其可能的作用机制,了解Pim1基因在AML患者原代细胞中的表达情况. 构建Pim1过表达和空载的荧光质粒,用慢病毒载体系统包装带有GFP荧光标记的Pim1慢病毒和对照病毒,同时建立Pim1慢病毒稳定感染U937细胞系和对照病毒稳定感染U937细胞系;CCK-8检测和流式细胞术检测Pim1基因表达上调对U937细胞增殖、凋亡影响;应用Transwell趋化试验了解Pim1基因表达对AML细胞趋化的影响;应用Western blot检测P... | zh-cn |
pair_31204917 | To investigate the effect of Bmi-1 gene silence on the proliferation ability of K562 cells in vitro and in vivo, and to explore the relation of molecular mechanism between proliferation ability of K562 cells in vitro and in vivo with PTEN/pAKT signaling pathway. The Bmi-1 small interference RNA (siRNA) sequences were t... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Bmi-1-siRNA通过PTEN/pAKT通路调控K562细胞体内外的增殖能力. 观察Bmi-1基因沉默对白血病K562细胞体内外增殖能力的影响并初步探究二者之间的分子机制是否与PTEN/pAKT通路有关. 将Bmi-1小干扰RNA(siRNA)序列转染到K562细胞中降低其Bmi-1的表达;应用MTT比色法和软琼脂集落形成实验检测Bmi-1- siRNA对K562细胞体外增殖的影响;裸鼠皮下接种各组细胞,观察Bmi-1- siRNA对K562细胞在裸鼠体内的致瘤能力的影响;应用Western blot检测Bmi-1、PTEN、p-AKT等蛋白的表达. Bmi-1-siRNA有效沉默了Bmi-1基因mRNA和蛋白的表达;沉默Bmi... | zh-cn |
pair_31204918 | To explore the prognostic factors of elderly AML patients, as well as the application and prognostic value of comprehensive geriatric assessment(CGA) in elderly AML patients in China, so as to determine a suitable comprehensive assessment method that can predict survival and guide treatment of patients in Chinese peopl... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 84例老年急性髓系白血病患者的临床特点及预后分析. 探讨老年AML患者的预后因子,以及老年综合评估在中国老年AML患者中的应用及预后价值,从而确定适合中国人的预测生存并指导治疗选择的老年综合评估方法. 回顾性分析2007年10月至2017年12月我科诊断的年龄≥60岁的84例AML患者的病历资料,分析临床、病理以及老年综合评估相关预后因子. 所有患者的中位年龄70(60-91)岁,男女比例为:1.9∶1(55∶29),中位OS为 9(1-125)个月,1年OS率为35.3%,5年OS率为12.6% 。年龄分组、第1疗程缓解状态、是否难治复发、初诊白细胞数分组、乳酸脱氢酶和血肌酐水平是影响OS的危险因素;第1疗程缓解状态、是否难治复发... | zh-cn |
pair_31204920 | To investigate the effect of stably down-regulating the FMI expression of K562 cells on the sensitivity of K562 cells to Imatinib (IM) and its possible mechanism. Western-blot was used to detect the expression of FMI protein in K562 cells and peripheral blood mononuclear cells from the patients with chronic myelogenous... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 稳定下调K562细胞株FMI表达对其甲磺酸伊马替尼药物敏感性的影响. 探讨稳定下调K562细胞株FMI表达对其甲磺酸伊马替尼药物敏感性的影响及其可能的作用机制. 应用Western-blot方法分别检测K562细胞、慢性髓系白血病(CML)病人、慢性髓系急变病人及健康志愿者外周血单个核细胞FMI蛋白表达;设计靶向人FMI的特异性干扰序列,连接入慢病毒载体LV3;用三质粒系统包装慢病毒颗粒,感染K562细胞,筛选稳定下调FMI的K562细胞;应用CCK8法鉴定K562细胞对伊马替尼药物敏感性的变化,AnnexinⅤ/7-AAD双标记的流式细胞术检测细胞凋亡,荧光定量PCR检测白血病细胞FMI、Fz8的转录水平,Western-Blot... | zh-cn |
pair_31204922 | To explore the values of 4 prognostic score systems in evaluation of clinical effecacy for patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatnib mesylate (IM) and the relationship between 4 prognostic score systems and deep molecular response (MR4.5). The clinical data of... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 不同评分系统对初诊慢性髓系白血病患者临床疗效的预估价值. 探讨4种评分系统对甲磺酸伊马替尼(IM)治疗初诊慢性髓系白血病慢性期(CML-CP)患者临床疗效的预估价值,以及与深层分子学反应(MR4.5)之间的相互关系. 回顾性分析我院2008年1月至2017年12月接受IM治疗的240例初诊CML-CP患者的临床资料,根据4种评分系统分别进行危险度分层,并分析4种评分系统与3个月早期分子学反应(3M-EMR)、6个月完全细胞遗传学反应(6M-CCyR)和12个月主要分子学反应(12M-MMR)之间的关系,以及4种评分系统与MR4.5之间的相关性. 240例患者治疗满3个月时,有219例患者评估EMR,其中有164例(74.9%)患者获... | zh-cn |
pair_31204923 | To explore the effect and possible mechanism of PI3K/mTOR inhibitor XL765 on KG-1 cells in vitro. The effect of XL765 on cell proliferation was detected by CCK-8 assay. The colony formation test (200 cells were plated in a plate for 9 days) was used to detect the effect of XL765 on the colony forming ability of KG-1 ce... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 信号通路抑制剂XL765对人白血病KG-1细胞株的抑制效应研究. 探讨PI3K/mTOR信号通路抑制剂XL765(SAR245409, Voxtalisib)对人急性髓系白血病细胞株KG-1细胞的抑制效应及可能的作用机制. 应用CCK-8法检测XL765对KG-1细胞增殖的影响;平板集落形成实验检测XL765对KG-1细胞集落形成的抑制情况;Annexin V/PI双染色流式细胞术检测XL765对细胞凋亡的影响;实时荧光定量PCR检测细胞凋亡相关基因的表达;Western blot法检测凋亡相关蛋白的表达水平及信号通路分子磷酸化水平的变化. XL765能有效抑制KG-1细胞的增殖,抑制率呈剂量依赖性增加;与DMSO处理组相比,加入X... | zh-cn |
pair_31204924 | RAG1 plays important roles in lymphopoiesis and immune system, its dysfunction may result in the malignancies of hemopoietic system. The aim of this study was to investigate the characteristics of RAG1 expression in adult B-cell acute lymphoblastic leukemia (B-ALL), and to analyze the clinical significances. Quantitati... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 成人B细胞性急性淋巴细胞白血病RAG1表达特点及临床意义. 探讨成人B细胞性急性淋巴细胞白血病(B-ALL)中RAG1基因的表达特点及其临床意义. 应用实时定量PCR方法检测104例初发、22例复发成人B-ALL患者和30例正常对照者RAG1基因的表达,分析基因表达特点及其与临床和实验室参数之间的关系. 初发、复发成人B-ALL患者RAG1基因表达水平均高于正常对照者(3.94 vs 1.23)(P<0.001);(5.86 vs 1.23)(P<0.01)。6例初发与复发患者成对标本分析显示,RAG1表达水平在疾病复发时显著高于初发(13.65 vs 2.31)(P<0.01)。IKZF1基因外显子3-6缺失的异构体Ikaros ... | zh-cn |
pair_31204925 | To study whether the Bmi-1 gene can be a biomarker for analysis of clinical risk stratification and prognosis of ALL patients. The expression level of Bmi-1 gene in bone marrow samples from 127 cases of newly diagnosed ALL was detected by qRT-PCR, at the same time the expression level of Bmi-1 protein in bone marrow sa... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | Bmi-1作为儿童急性淋巴细胞白血病预后分子标志物的研究. 研究Bmi-1基因能否作为儿童ALL的临床风险分析和预后分析的生物标志物. 通过qRT-PCR检测127例初诊ALL患儿骨髓标本中Bmi-1基因的表达水平,同时应用Western blot技术检测对应标本中Bmi-1蛋白的表达情况。根据不同的临床风险分级,将收集到的骨髓标本分为高危、中危、低危3组,分析Bmi-1的表达与ALL患儿临床风险分级之间的关系。根据强的松试验敏感性将标本分为敏感和不敏感2组,比较Bmi-1的表达在2组之间是否有差异。根据Bmi-1表达量的中位数,将标本分成高水平和低水平2组,依据Kaplan-Meier方法计算儿童ALL患者预后与Bmi-1表达水平... | zh-cn |
pair_31204926 | To establish a method for detecting the exosomal PML-RARA fusion gene expression by droplet digital PCR (ddPCR). By using Taqman probe-based ddPCR technique, the method that able to detect both long and short isoforms of PML-RARA fusion gene transcripts was established. RNA from PML-RARA negative cell line HL-60 as neg... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 微滴式数字PCR技术检测外泌体PML-RARA融合基因的表达. 利用微滴式数字PCR技术检测外泌体中PML-RARA融合基因表达水平. 使用基于Taqman探针法的ddPCR技术,建立可检测长型和短型PML-RARA融合基因转录本的方法。以PML-RARA阴性细胞株HL-60细胞的RNA逆转录合成的cDNA为阴性对照建立空白检测限(LOB);以表达长型PML-RARA融合基因的NB4细胞RNA逆转录合成的cDNA和含短型PML-RARA cDNA的重组质粒为模板分别确定两者的最低检测限(LOD);并检测NB4细胞培养上清来源的外泌体和急性早幼粒白血病患者血清来源的外泌体中PML-RARA融合基因的表达情况. 采用ddPCR技术针对长... | zh-cn |
pair_31204928 | To investigate the expression and clinical significance of RhoH gene in bone marrow cells of leukemia patients. 31 cases of leukemia and 15 cases of non-tumor as controls were collected. The expression of RhoH in bone marrow cells was detected by real-time quantitative PCR (RQ-PCR). The median expression level of RhoH ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | RhoH 基因在初诊急性白血病患者中的表达差异及其临床意义. 探讨RhoH基因在白血病患者骨髓细胞中的表达及其临床意义. 收集本院初诊白血病患者31例、非肿瘤患者15例。应用实时荧光定量PCR(real-time quantitative PCR,RQ-PCR)法检测骨髓细胞中RhoH表达,以RhoH的中位表达水平作为界值,将初诊患者分为RhoH高表达组和低表达组,并分析不同RhoH表达水平与患者初诊时临床特征和预后之间的关系. 31例AL患者骨髓细胞标本RhoH mRNA相对表达量显著低于对照组,ALL组显著低于AML组(P<0.05);与RhoH高表达组相比,RhoH低表达组骨髓原始细胞比例、LDH水平显著升高(P<0.05);... | zh-cn |
pair_31204930 | To explore the correlation of EB virus infection with the prognosis of B-ALL children. The peripheral blood of children with newly diagnosed B-ALL admitted in Children's Hospital of Chongqing Medical University from January 2012 to December 2017 were collected, and the EBV DNA in plasma was detected by real-time quanti... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | EB病毒感染与急性B淋巴细胞白血病患儿的预后相关性研究. 探讨EB病毒感染与B-ALL患儿预后的关系. 收集2012年1月- 2017年12月在重庆医科大学附属儿童医院初诊为B-ALL的住院患儿外周血,运用实时荧光定量PCR的方法检测患儿血浆中EB病毒DNA。收集患儿病历资料,关联性分析EBV感染与B-ALL患儿预后的相关性. 162名B-ALL患儿中EB病毒感染率为41.36%。单因素分析结果显示,EB病毒感染的患儿预后差,生存期较短的风险高于未感染患儿(HR=2.373,95% CI:1.129-4.987),且差异有统计学意义(P=0.023)。多因素分析结果与单因素分析结果一致,这表明EB病毒感染是B-ALL患儿预后不良的独... | zh-cn |
pair_31204934 | To investigate the clinical manifestations pathologic features, treatment options and prognosis of patients with bone lymphoma. The clinical characteristics, pathologic features, treatment and prognosis of 34 BL patients diagnosed by histopathologic method or/and PET-CT and treated in first hospital of peking universit... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 真实世界骨淋巴瘤的病理特征、治疗选择与患者预后评估. 探讨骨淋巴瘤的临床特点、病理特征、治疗方法和患者预后. 回顾性分析北京大学第一医院2004年1月至2018年4月收治的34例骨淋巴瘤患者的临床特征、病理特点、治疗及预后. 34例骨淋巴瘤患者的中位年龄为56 岁,男、女性别比例为1.43∶1。原发性骨髓瘤(PBL) 8例,继发性骨髓瘤(SBL) 26例,PBL与SBL之比为0.31∶1。PBL患者常无明显的全身症状,多因骨痛或病理性骨折起病。病理类型以DLBCL最多,占55.88%。目前骨淋巴瘤的治疗方法为化疗,或化疗辅以放疗或手术,有条件者行造血干细胞移植治疗。本研究中骨淋巴瘤患者平均生存期为3.49年,中位生存期为3年, 3年... | zh-cn |
pair_31204935 | To explore the clinical pathological features of the patients with diffuse large B cell lymphoma (DLBCL) and their prognostic factors. The prognosis of the clinical pathological features and their influence on prognosis of 177 patients diagnosed as DLBCL at the first visit from January 2013 to May 2017 in our hospital ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 年轻弥漫大B细胞淋巴瘤患者的临床病理特征与预后分析. 探讨弥漫大B细胞淋巴瘤(diffuse large B cell lymphoma,DLBCL)患者的临床病理特征及其对预后评估作用. 选取本院2013年1月至2017年5月177例确诊为弥漫大B细胞淋巴瘤的初治患者,回顾性分析其临床病理特征及其对预后的影响. 单因素预后分析发现,分期Ⅲ-Ⅳ期(P=0.004,P=0.029)、ECOG评分2-4分(P=0.003,P=0.042)、结外受累>1处(P=0.000,P=0.031)、异常升高的LDH值(P=0.000,P=0.046)为影响患者OS与PFS的危险因素;B症状(P=0.020)、异常升高的β2-MG值(P=0.020... | zh-cn |
pair_31204936 | To analyze the clinical features and to explore the therapeutic efficacy and prognostic factors of children with anaplastic large cell lymphoma (ALCL). The clinical data of 18 children with ALCL admitted in Department of Pediatric Hematology, Union Hospital of Fujian Medical University from April 2011 to November 2017 ... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | 18例儿童系统性ALK阳性间变大细胞淋巴瘤的临床特征及患儿预后分析. 分析儿童间变大细胞淋巴瘤(ALCL)的临床特征,探讨治疗效果及预后因素. 收集2011年4月至2017年11月期间在福建医科大学附属协和医院小儿血液科收治的18例ALCL的临床、实验室及病理资料进行总结分析. 男女比例为2∶1,中位发病年龄6(0.9-11.3)岁,B症状阳性13例,17例首发症状为淋巴结肿大,所有病例伴有多部位受累。4例临床分期Ⅱ期,11例临床分期Ⅲ期,3例Ⅳ期。9例白细胞数增高,CRP>20 mg/L的8例,病理结果均为ALK阳性的间变大细胞淋巴瘤,Ki-67在40%-90%之间。2例在治疗前死亡,1例失访。15例采用CCCG-BNHL-201... | zh-cn |
pair_31204937 | To investigate the role of myeloid-derived suppressor cells (MDSC) in the prognosis of patients with diffuse large B cell lymphoma (DLBCL). The peripheral blood of 52 DLBCL patients and 30 healthy volunteers was collected. The CD14<sup>+</sup>HLA-DR<sup>low/-</sup> was used as the immune marker for MDSC. The role of MD... | en | lexi-ml/wmt_22_dataset_en_zh-cn | train | text | CD14<sup>+</sup>HLA-DR<sup>low/-</sup>髓系来源抑制性细胞在弥漫大B细胞淋巴瘤中的预后价值. 探讨髓系来源抑制性细胞(MDSC)在弥漫大B细胞淋巴瘤(DLBCL)患者预后中的作用. 收集52例初诊DLBCL患者和30例健康志愿者外周血,以CD14<sup>+</sup>HLA-DR<sup>low/-</sup>作为MDSC的免疫标记,结合相关临床病理资料分析MDSC 在DLBCL 预后中的作用. 初诊DLBCL患者外周血MDSC水平相比对照组明显升高(P<0.01)。MDSC在DLBCL患者中表达与临床分期、乳酸脱氢酶(LDH)水平及IPI评分相关(P< 0.01),与性别、年龄、有无B症状未见... | zh-cn |
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