pair_id
stringlengths
13
13
source_text
stringlengths
68
8.64k
source_lang
stringclasses
1 value
source_dataset
stringclasses
7 values
split
stringclasses
1 value
audio_text
stringclasses
1 value
target_text
stringlengths
4
9.21k
target_lang
stringclasses
7 values
pair_30991784
Disfunction of Eustachian tube will cause negative pressure of middle ear, which may result in tympanic membrane retraction pocket. Severe pocket can consequently cause cholesteatoma. In clinical practice it is not uncommon to find a cholesteatoma limited to epitympanum, with an otherwise normal pars tensa and mesotymp...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
咽鼓管通气障碍产生中耳负压是鼓膜内陷囊袋的发生机制,内陷囊袋如果不断加深,就可能导致后天原发性胆脂瘤。为什么临床上常看到松弛部胆脂瘤患者的紧张部和中鼓室是正常的,耳内镜技术的发展给出了清晰的答案:大多数人的上鼓室通气完全依赖鼓峡,在咽鼓管功能恢复后仍长期封闭,上鼓室就形成了'选择性低通气',由此可能出现最常见的后天原发性胆脂瘤。本文就中耳通气影响因素和上鼓室选择性通气障碍的研究进展作一综述。.
zh-cn
pair_30991786
With the rapid development of modern equipment and widespread familiarity with the relative knowledge, endoscopic ear surgery has attracted many oto-surgeons and is becoming more popular in primary hospitals in China. Standardized management of perioperative period in this field can help surgeons shorten the learning c...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着内镜设备的发展,耳内镜手术引起众多耳外科医生的兴趣,耳内镜外科逐渐在全国基层医院普及。规范的围手术期管理有助于初学者缩短学习曲线、减少并发症的发生。本文对耳内镜技术相关的设备器械、术前检查、知情同意、患者术前准备、手术室布局、术中可能遇到的困难和应对措施以及术后处理和随访等围手术期管理做了详细介绍。.
zh-cn
pair_30991787
Based on anatomy and clinical operation, this article discussed the anatomical structure of temporal bone and its contiguous relationship under oto-endoscope, through two approaches: the natural external auditory canal and the enlarged external auditory canal. To give an account of the anatomical characteristics of tem...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
本文结合解剖及临床手术经验,在耳内镜视角的基础上,重新探讨和认识颞骨各解剖结构及其毗邻关系,通过经自然的外耳道和经扩大的外耳道两种入路,阐述耳内镜下颞骨解剖特点。.
zh-cn
pair_30992631
To assess the performance of an early warning, alert and response system (EWARS) developed by the World Health Organization (WHO) - EWARS in a Box - that was used to detect and control disease outbreaks after Cyclone Winston caused destruction in Fiji on 20 February 2016. Immediately after the cyclone, Fiji's Ministry ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
旨在评估世界卫生组织开发的早期预警、警报和响应系统 (EWARS in a Box) 的性能,其被用于检测和控制 2016 年 2 月 20 日温斯顿飓风在斐济大规模破坏后的疾病爆发。. 飓风侵袭后,斐济卫生和医疗服务部在世界卫生组织的支持下,开始实施早期预警、警报和响应系统 (EWARS in a Box),这是一个基于智能手机、自动化的早期预警监控系统,可用于卫生紧急状态下的快速部署。采用基于指标和基于事件的监测方法。对 2016 年 3 月 7 日至 5 月 29 日期间的系统性能进行了评估。在访谈中,我们使用半结构式问卷和横断面调查,评估使用该系统用户的用户体验。使用早期预警、警报和响应系统 (EWARS) 数据库的数据来评...
zh-cn
pair_30992631
To assess the performance of an early warning, alert and response system (EWARS) developed by the World Health Organization (WHO) - EWARS in a Box - that was used to detect and control disease outbreaks after Cyclone Winston caused destruction in Fiji on 20 February 2016. Immediately after the cyclone, Fiji's Ministry ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Évaluer les performances du système d'alerte et d'intervention rapides conçu par l'Organisation mondiale de la Santé (OMS) baptisé « <i>EWARS in a Box</i> », qui a été utilisé pour détecter et contrôler les flambées épidémiques après le passage destructeur du cyclone Winston, à Fidji, le 20 février 2016. Immédiatement ...
fr
pair_30992631
To assess the performance of an early warning, alert and response system (EWARS) developed by the World Health Organization (WHO) - EWARS in a Box - that was used to detect and control disease outbreaks after Cyclone Winston caused destruction in Fiji on 20 February 2016. Immediately after the cyclone, Fiji's Ministry ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Evaluar el funcionamiento de un sistema de alerta temprana, alerta y respuesta (EWARS, por sus siglas en inglés) desarrollado por la Organización Mundial de la Salud (OMS), EWARS in a Box, que se utilizó para detectar y controlar los brotes de enfermedades después de que el ciclón Winston causara destrucción en Fiji el...
es
pair_30992631
To assess the performance of an early warning, alert and response system (EWARS) developed by the World Health Organization (WHO) - EWARS in a Box - that was used to detect and control disease outbreaks after Cyclone Winston caused destruction in Fiji on 20 February 2016. Immediately after the cyclone, Fiji's Ministry ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Оценка качества работы системы раннего предупреждения, оповещения и реагирования (early warning, alert and response system, EWARS), разработанной Всемирной организацией здравоохранения (ВОЗ), в пакетном варианте, которая использовалась для выявления и контроля вспышек заболеваний после разрушений, вызванных циклоном «У...
ru
pair_30992633
To assess adoption of World Health Organization (WHO) guidance into national policies for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) and to monitor implementation of guidelines at facility level in rural Malawi, South Africa and the United Republic of Tanzania. We summarize...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
旨在评估将世界卫生组织 (WHO) 的指导方针纳入艾滋病毒 (HIV) 母婴传播预防 (PMTCT) 政策,并监测马拉维、南非和坦桑尼亚联合共和国的农村地区医疗机构层面指导方针的实施情况。. 我们总结了国家艾滋病毒母婴传播预防政策和世界卫生组织指南自 2013-2016 年为孕产妇和婴儿护理联动提供的 15 项指标。在 2013 年至 2015 年和 2015 年至 2016 期间分别对 46 个医疗机构、服务于五大医疗和人口监控系统的人群进行了两轮调查。我们对机构管理者进行了结构式问卷调查,以描述服务的提供情况。我们根据地点和调查轮次,报告实施各项指标的机构比例以及缺货的频率和持续时间。. 所有国家中,影响产妇和预防艾滋病毒母婴传...
zh-cn
pair_30992633
To assess adoption of World Health Organization (WHO) guidance into national policies for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) and to monitor implementation of guidelines at facility level in rural Malawi, South Africa and the United Republic of Tanzania. We summarize...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Évaluer la transposition des recommandations de l'Organisation mondiale de la Santé (OMS) dans les politiques nationales de prévention de la transmission mère-enfant (PTME) du virus de l'immunodéficience humaine (VIH) et contrôler l'application de ces politiques dans les centres de santé de zones rurales d'Afrique du S...
fr
pair_30992633
To assess adoption of World Health Organization (WHO) guidance into national policies for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) and to monitor implementation of guidelines at facility level in rural Malawi, South Africa and the United Republic of Tanzania. We summarize...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Evaluar la adopción de las directrices de la Organización Mundial de la Salud (OMS) en las políticas nacionales de prevención de la transmisión del virus de la inmunodeficiencia humana (VIH) de madre a hijo y supervisar la aplicación de las directrices a nivel de las instalaciones sanitarias en las zonas rurales de Mal...
es
pair_30992633
To assess adoption of World Health Organization (WHO) guidance into national policies for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) and to monitor implementation of guidelines at facility level in rural Malawi, South Africa and the United Republic of Tanzania. We summarize...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Оценка включения рекомендаций Всемирной организации здравоохранения (ВОЗ) в национальные стратегии профилактики передачи вируса иммунодефицита человека (ВИЧ) от матери ребенку (РМТСТ) и отслеживание внедрения таких рекомендаций на уровне объектов здравоохранения в сельских районах Малави, Объединенной Республики Танзан...
ru
pair_30992634
To facilitate the policy response to noncommunicable diseases in Thailand, parliament adopted the Health Promotion Foundation Act in 2001. This Act led to the establishment of an autonomous government body, the Thai Health Promotion Foundation, called ThaiHealth. The foundation receives its revenue from a 2% surcharge ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为了促进泰国对非传染性疾病的政策响应,议会于 2001 年通过了《泰国健康促进基金会法》。该法案促成了自治政府机构,即泰国健康促进基金会(简称 ThaiHealth)的成立。该基金会的收入来自烟草和酒精消费税 2% 的附加费。该基金会支持宣传非传染性疾病风险因素(例如吸烟、酗酒与久坐不动)的证据生成、活动集会以及社会动员。平均而言,其年收入为 1.2 亿美元。ThaiHealth 举办过的著名公共活动有:倡导学校提供不含糖的碳酸饮料;在为期三个月的守夏节(佛教的四旬斋节)的戒绝酒精活动;以及全国范围内的体育活动。吸烟人群占比从 2001 年的 22.5% 降低至 2014 年的 18.2%。人均饮酒量从 2005 年的 8.1 升纯...
zh-cn
pair_30992634
To facilitate the policy response to noncommunicable diseases in Thailand, parliament adopted the Health Promotion Foundation Act in 2001. This Act led to the establishment of an autonomous government body, the Thai Health Promotion Foundation, called ThaiHealth. The foundation receives its revenue from a 2% surcharge ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Afin de soutenir l'action politique concernant les maladies non transmissibles en Thaïlande, le Parlement a adopté une loi sur la Fondation pour la promotion de la santé en 2001. Cette loi a conduit à l'établissement d'un organisme gouvernemental autonome, la Fondation thaïlandaise pour la promotion de la santé, appelé...
fr
pair_30992634
To facilitate the policy response to noncommunicable diseases in Thailand, parliament adopted the Health Promotion Foundation Act in 2001. This Act led to the establishment of an autonomous government body, the Thai Health Promotion Foundation, called ThaiHealth. The foundation receives its revenue from a 2% surcharge ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Para facilitar la respuesta política a las enfermedades no contagiosas en Tailandia, el Parlamento aprobó en 2001 la Ley de la Fundación para la promoción de la salud. Esta ley dio lugar a la creación del organismo gubernamental autónomo, la Fundación tailandesa para la promoción de la salud, denominada ThaiHealth. La ...
es
pair_30992634
To facilitate the policy response to noncommunicable diseases in Thailand, parliament adopted the Health Promotion Foundation Act in 2001. This Act led to the establishment of an autonomous government body, the Thai Health Promotion Foundation, called ThaiHealth. The foundation receives its revenue from a 2% surcharge ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
С целью содействия принятию мер по программе борьбы с неинфекционными заболеваниями в Таиланде парламент страны принял Закон о фонде развития здравоохранения в 2001 году. В соответствии с данным законом был создан независимый правительственный орган — Фонд развития здравоохранения Таиланда (ThaiHealth). Прибыль фонда с...
ru
pair_30992635
Bangladesh has achieved a high share of tax in the price of cigarettes (greater than the 75% benchmark), but has not achieved the expected health benefits from reduction in cigarette consumption. In this paper we explore why cigarette taxation has not succeeded in reducing cigarette smoking in Bangladesh. Using governm...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
孟加拉国对卷烟价格(高于基准价格 75%)实施高税收份额,但此举并未降低卷烟消费量,实现预期的健康效益。本文中,我们探讨了孟加拉国烟草税未能成功减少吸烟的原因。根据 2006 年至 2017 年的政府记录,我们将已纳税卷烟的销售趋势与卷烟消费税结构以及卷烟税及其价格的变化联系起来。我们分析了孟加拉国全球成人烟草调查的吸烟率数据,旨在研究 2009 年和 2017 年不同烟草产品的消费情况。根据烟草制造商的年度报告和其他文献,我们研究了烟草市场的供求因素。除卷烟的可负担性增加之外,似乎还存在另外三大因素,削弱了税收和价格上涨在减少孟加拉国国卷烟消费方面的有效性。首先,多层消费税结构扩大了品牌之间的价格差异,并鼓励吸烟者从高价卷烟向下寻...
zh-cn
pair_30992635
Bangladesh has achieved a high share of tax in the price of cigarettes (greater than the 75% benchmark), but has not achieved the expected health benefits from reduction in cigarette consumption. In this paper we explore why cigarette taxation has not succeeded in reducing cigarette smoking in Bangladesh. Using governm...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Le Bangladesh applique un fort pourcentage de taxe sur les prix du tabac (au-delà du référent habituel de 75% du prix de détail) sans pour autant avoir atteint le bénéfice sanitaire attendu de réduction du tabagisme. Cet article se penche sur les raisons pour lesquelles la taxation du tabac n'est pas parvenue à réduire...
fr
pair_30992635
Bangladesh has achieved a high share of tax in the price of cigarettes (greater than the 75% benchmark), but has not achieved the expected health benefits from reduction in cigarette consumption. In this paper we explore why cigarette taxation has not succeeded in reducing cigarette smoking in Bangladesh. Using governm...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Bangladesh ha alcanzado una elevada cuota de impuestos en el precio de los cigarrillos (superior al 75 % de referencia), pero no ha logrado los beneficios para la salud esperados de la reducción del consumo de cigarrillos. En este artículo exploramos por qué los impuestos sobre los cigarrillos no han logrado reducir el...
es
pair_30992635
Bangladesh has achieved a high share of tax in the price of cigarettes (greater than the 75% benchmark), but has not achieved the expected health benefits from reduction in cigarette consumption. In this paper we explore why cigarette taxation has not succeeded in reducing cigarette smoking in Bangladesh. Using governm...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
В Бангладеш достигнута высокая планка налогообложения сигарет (более 75% базисного показателя), но ожидаемой пользы для здравоохранения от сокращения потребления сигарет добиться не удалось. В данной статье рассмотрены причины, по которым налог на сигареты не привел к сокращению курения в Бангладеш. Используя правитель...
ru
pair_30992636
Hepatitis B virus (HBV) infection is a major public health problem worldwide. China has the world's largest burden of HBV infection and will be a major contributor towards the global elimination of hepatitis B disease by 2030. The country has made good progress in reducing incidence of HBV infection in the past three d...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
乙型肝炎病毒 (HBV) 感染是一个严重的全球公共卫生问题。中国是世界上乙型肝炎病毒 (HBV) 感染负担最重的国家,也是实现 2030 年前全球消除乙肝目标的主要贡献者。近 30 年来,我国的乙肝病毒感染发生率呈现显著下降趋势。取得这些成就的主要原因在于儿童疫苗接种的覆盖率高,以及新生儿在出生时及时接种疫苗【预防乙型肝炎病毒 (HBV) 母婴传播】的覆盖率高(均高于 95%)。然而,中国要在 2030 年前实现乙肝死亡率降低 65% 这一目标,仍面临巨大挑战。根据世界卫生组织《2016-2021 年全球卫生部门病毒性肝炎战略》目标,我们强调在中国进一步消除乙型肝炎病毒 (HBV) 的重点行动。为了实现降低死亡率的影响指标,我们建议...
zh-cn
pair_30992636
Hepatitis B virus (HBV) infection is a major public health problem worldwide. China has the world's largest burden of HBV infection and will be a major contributor towards the global elimination of hepatitis B disease by 2030. The country has made good progress in reducing incidence of HBV infection in the past three d...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Les infections par le virus de l'hépatite B (VHB) constituent un problème de santé publique majeur à l'échelle mondiale. La Chine est le pays le plus lourdement touché par les infections par le VHB et sa contribution sera donc essentielle pour atteindre l'objectif d'élimination de l'hépatite B dans le monde à l'horizon...
fr
pair_30992636
Hepatitis B virus (HBV) infection is a major public health problem worldwide. China has the world's largest burden of HBV infection and will be a major contributor towards the global elimination of hepatitis B disease by 2030. The country has made good progress in reducing incidence of HBV infection in the past three d...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
La infección por el virus de la hepatitis B (VHB) es un gran problema de sanidad pública en todo el mundo. China tiene la mayor carga de infección por VHB en el mundo y será uno de los principales contribuyentes a la eliminación mundial de la enfermedad de la hepatitis B para 2030. En las últimas tres décadas, el país ...
es
pair_30992636
Hepatitis B virus (HBV) infection is a major public health problem worldwide. China has the world's largest burden of HBV infection and will be a major contributor towards the global elimination of hepatitis B disease by 2030. The country has made good progress in reducing incidence of HBV infection in the past three d...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Инфекция вирусом гепатита В (HBV) представляет собой одну из самых серьезных проблем общественного здравоохранения во всем мире. Бремя этого заболевания в Китае крупнейшее в мире, и эта страна должна будет внести основной вклад в ликвидацию гепатита В в масштабах планеты к 2030 году. Китай хорошо продвинулся на пути сн...
ru
pair_30993733
To identify and describe the various patterns of parents' perspectives on avoiding secondhand smoke exposure. Q methodology was applied to investigate the parental perspectives of 50 parents. The study was implemented from September-December 2016. Forty-two Q-statements were constructed based on the literature related ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的: 识别并描述家长对避免二手烟暴露的看法的不同模式。 设计: 采用Q方法论来对50位家长的观点进行调查。 方法: 该研究于2016年九月至十二月实施。根据和父母态度相关的文献和防止幼童接触二手烟的防护实践,创建了四十二份问题陈诉。参与者对一系列Q类问题进行排序,将不同陈诉排列在Q网格中。采用PQ方法2.35软件进行主要成分分析,以确定不同父母的观点模式。 结果: 一共有五种共同观点模式来自于此分析,占了总方差的62%: (a) 对在非吸烟区面对吸烟者缺乏信心;(b) 意识到了健康危害,但尚未做好采取预防措施的准备;(c) 强调父母责任和行为指导;(d) 受立法保护的健康权意识;(e) 强烈的采取保护行动的意识。 结论: 我们的研...
zh-cn
pair_30993749
To evaluate the effectiveness of educational interventions in improving medication adherence among adult patients diagnosed with hypertension, hyperlipidaemia and/or diabetes. This review was conducted with reference to methods set out in the Cochrane Handbook for Systematic Reviews of Interventions (PROSPERO registrat...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的: 在于评价,教育干预措施能有效提高高血压、高脂血症和/或糖尿病成年患者的服药依从性。 设计: 通过参考《Cochrane 干预措施系统评价手册》(PROSPERO 登记号:CRD42016053402)中规定的方法进行审查。 资料来源: 搜索了七个电子数据库(从2003年至2016年)。 综述方法: 系统性地评估了证据质量和研究强度,然后由两位审查者使用Cochrane 协作组织的工具评估了偏倚风险。 结果: 十八项随机对照试验展现了教育干预措施改善服药依从性的低至中等质量证据。2型糖尿病患者受益于教育干预措施,但高血压患者则没有。没有发现针对高脂血症参与者进行的随机对照试验(RCT)。在家进行的教育比在诊所进行的教育显示出更...
zh-cn
pair_30994268
To examine the effects of pig manure application on dry matter production, nitrogen accumulation and distribution, grain yield and nitrogen use efficiency of rice and wheat, the field trial was conducted with wheat 863 and rice 498. Fertilization treatments consisted of seven rates of organic manure supply: control (CK...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
通过大田试验,以水稻(品种‘F优498’)-小麦(品种‘内麦863’)轮作体系为研究对象,根据成都平原稻麦种植体系常规施氮水平,设7个不同猪粪施用处理:对照(CK,无化学氮肥,无猪粪)、常规化肥(T<sub>1</sub>,无猪粪)、化肥减量25%+猪粪2500 kg·hm<sup>-2</sup>(T<sub>2</sub>)、化肥减量50%+猪粪5000 kg·hm<sup>-2</sup>(T<sub>3</sub>)、猪粪10000 kg·hm<sup>-2</sup>(T<sub>4</sub>)、猪粪15000 kg·hm<sup>-2</sup>(T<sub>5</sub>)和猪粪20000 kg·hm<sup>-2<...
zh-cn
pair_30994271
To investigate the effects of different planting patterns on soil nutrient contents, rice yield, nitrogen production efficiency, and apparent nutrient balance, a long-term field experiment was conducted in Changsha, Hunan, China. Four planting patterns were examined, including winter fallow-double cropping rice (CK), r...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
通过在湖南长沙双季稻田开展的冬闲-双季稻(CK)、黑麦草-双季稻(Ry-R-R)、紫云英-双季稻(Mv-R-R)和油菜-双季稻(Ra-R-R)4个种植模式的长期定位试验,分析不同种植模式对土壤养分含量、水稻产量、氮素生产效率和土壤养分表观平衡的影响.结果表明: Ry-R-R、Mv-R-R和Ra-R-R的土壤全氮和碱解氮含量显著高于CK,而土壤速效钾含量显著低于CK.与CK相比,Ry-R-R、Mv-R-R和Ra-R-R的晚稻氮肥偏生产力显著提升.Ry-R-R、Mv-R-R和Ra-R-R晚稻穗部的氮积累量显著高于CK;Ry-R-R、Mv-R-R和Ra-R-R茎叶的氮积累量均高于CK.Ry-R-R、Mv-R-R的水稻产量显著高于CK;水稻...
zh-cn
pair_30994272
Examining the effects of silicon fertilizer on the yield of double-cropping rice and the leaching loss of soil nitrogen (N) and phosphorus (P) could provide a basis for the optimization of formula fertilizer and the comprehensive control technique of agricultural surface source pollution in typical double cropping padd...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
研究硅肥对双季稻产量及土壤氮磷流失的影响,旨在为典型双季稻区施肥结构优化以及农田面源污染综合防控技术提供技术支撑.采用田间试验研究在相同氮磷肥基础上施0、750、1500、2250和3000 kg·hm<sup>-2</sup> (T<sub>0</sub>、T<sub>1</sub>、T<sub>2</sub>、T<sub>3</sub>、T<sub>4</sub>)硅肥对双季稻产量和氮磷吸收、田面水氮磷含量及土壤有效硅、有机质、碱解氮和有效磷含量的影响.结果表明:与不施硅肥处理(T<sub>0</sub>)比较,早、晚稻季水稻稻谷分别增产2.2%~30.4%和3.9%~9.2%;早、晚稻籽粒氮素积累量增加2.4%~47.3%、磷...
zh-cn
pair_30994273
To explore the effects of winter crops recycling into paddy field on soil carbon pool, we cultivated rape, Chinese milk vetch, ryegrass and potato in winter season after harvesting double-season rice, with fallow as control (CK). The contents of soil organic carbon (SOC) and labile organic carbon (LOC) in the harvest o...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为探讨冬季覆盖作物还田对稻田土壤碳库的影响,通过冬季种植油菜、紫云英、黑麦草、马铃薯,并以冬闲为对照进行大田试验,测定了不同冬季作物模式下早稻和晚稻的土壤有机碳、活性有机碳含量,并计算了稳态碳、碳库活度、活度指数、碳库指数和土壤碳库管理指数.结果表明:冬季作物还田增加了土壤有机碳含量,早稻和晚稻后的土壤有机碳含量比对照分别提高了1%~8%和3%~18%;油菜、黑麦草和紫云英还田均促进了土壤活性有机碳含量的增加,早稻后增加16.2%~84.2%,晚稻后增加24.4%~28.1%;冬季作物还田增加了土壤碳库管理指数,增加幅度为1.4%~41.8%.综上所述,冬种作物还田有利于提高土壤的固碳效应,并提升土壤质量,以种植黑麦草、紫云英的综合...
zh-cn
pair_30994274
Straw returning to soil can supplement soil nutrients required for crop growth, fertilize soil, and improve soil quality. To explore the long-term effect of straw returning on soil total nitrogen and its composition, herein, five treatments including no rice straw + no wheat straw returning (NRW), no rice straw + all w...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
秸秆还田可以补充作物生长所需的营养元素,也是提升土壤质量、构建肥沃耕层的关键措施.为揭示长期稻麦秸秆还田对土壤氮组分变化的影响,选取了江苏太湖地区稻田土壤为研究对象,设置了稻麦秸秆均不还田(NRW)、麦秆还田+稻秆不还田(W)、稻秆还田+麦秆不还田(R)、稻麦秸秆均半量还田(HRW)和稻麦秸秆均全量还田(ARW)共5个处理,研究秸秆还田量和秸秆类型对土壤全氮及氮组分构成变化的影响.结果表明: 与2007年相比,2017年除NRW处理外,其他处理土壤全氮和重组氮都增加,稻秆还田处理土壤全氮和重组氮含量最高;所有处理土壤轻组分有机质中氮含量都下降,ARW处理土壤轻组分有机质中氮含量下降最多,为8.09 g·kg<sup>-1</sup>...
zh-cn
pair_30994275
To understand the correlation between nitrogen fruiting efficiency and nitrogen utilization and remobilization in winter wheat, the differences and mutual relationships of nitrogen fruiting efficiency, nitrogen utilization and remobilization of winter wheat at different sowing dates (S<sub>1</sub>:24 September, S<sub>2...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为探讨不同播期冬小麦氮素出籽效率与氮素利用及转运的关系,在2014—2016年2个生长季,比较了不同播期(S<sub>1</sub>:9月24日;S<sub>2</sub>:10月1日;S<sub>3</sub>:10月8日;S<sub>4</sub>:10月15日;S<sub>5</sub>:10月22日)冬小麦氮素出籽效率、氮素利用和转运的差异及相互间的关系.结果表明: 籽粒产量和单位面积粒数在不同播期处理间未发生显著差异.推迟播期降低了地上部氮素积累量和穗部氮素积累量,从而降低了氮素吸收效率,但明显提高了氮素利用效率和氮素出籽效率.氮素出籽效率与氮素利用效率呈正相关,而与氮素吸收效率呈负相关,与氮素利用率无显著相关关系.氮素营...
zh-cn
pair_30994277
In two growing seasons of wheat (2016-2018), a field trial with Jimai 22 as test mate-rial was conducted in Shijiawangzi Village, Yanzhou City, Shandong Province. Under three nitrogen levels of 150 (N<sub>1</sub>), 180 (N<sub>2</sub>) and 210 (N<sub>3</sub>) kg·hm<sup>-2</sup>, two irrigation-fertilization methods were...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
于2016—2018年小麦生长季,在山东省兖州市史家王子村进行田间试验,供试品种为‘济麦22’,在150(N<sub>1</sub>)、180(N<sub>2</sub>)和210(N<sub>3</sub>) kg·hm<sup>-2</sup> 3个施氮量下,拔节期设置畦灌和撒施追氮(W<sub>1</sub>)及微喷带灌溉和追氮水肥一体化(W<sub>2</sub>)两种灌溉施氮方式,研究了测墒补灌条件下灌溉施氮方式对小麦水分利用、光合特性及干物质积累与转运的影响.结果表明: 同一施氮量条件下,W<sub>2</sub>两年度灌浆期7日平均棵间蒸发量均显著低于W<sub>1</sub>处理,60~160 cm 土层土壤水分消耗...
zh-cn
pair_30994279
Based on a field experiment on conservation tillage over 15 years in Weibei Highland maize cropland, six conservation tillage patterns, i.e., conventional tillage (CT), no-tillage (NT), no-tillage plus biochar (NB), no-tillage and straw mulching (NS), no-tillage and plastic film mulching (NF), and no-tillage and straw-...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
通过渭北旱塬春玉米15年定位试验,研究6种保护性耕作方式,即传统翻耕(CT)、免耕(NT)、免耕配施生物炭(NB)、免耕秸秆覆盖(NS)、免耕地膜覆盖(NF)和免耕秸秆地膜覆盖(NSF)对土壤水分与硝态氮淋溶的影响,探索适宜于该区可持续发展的农田管理措施.结果表明: 与NT相比,第一次水分补给时期0~100 cm土层,CT处理水分补给量无显著差异,NS、NB、NSF和NF处理显著降低;在100~300 cm土层,NS、NB、NF和NSF处理显著增加了水分补给量,CT显著低于NT处理.第二次水分补给时期,水分补给主要集中在0~100 cm土层,且各处理与NT水分补给量无显著差异.水分消耗时期,各处理与NT处理在0~100 cm土层消耗...
zh-cn
pair_30994289
To understand the characteristics of ammonia volatilization in Losses Plateau, an experiment was conducted in a typical solar greenhouse involving four treatments. Intermittent ventilation chamber method was used to measure NH<sub>3</sub> volatilization over the period of tomato-watermelon rotation. The results showed ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为探究黄土高原地区日光温室果蔬栽培中氨挥发特征,在陕西省杨凌区选择当地典型的日光温室,设置4个不同的水氮处理,采用密闭式间歇抽气法监测番茄-西瓜轮作季的氨挥发特征.结果表明: 日光温室栽培土壤氮素转化快,施氮处理施肥后第1~2天氨挥发出现峰值,氨挥发峰值为0.26~2.02 kg N·hm<sup>-2</sup>·d<sup>-1</sup>,7 d左右各处理氨挥发通量相近;施氮处理间氨累积排放量无显著差异;相同施氮量条件下,降低灌溉量氨累积排放量两季平均增加了46.7%;不同种植季氨平均排放通量和累积排放量均表现为西瓜季高于番茄季,西瓜季高温促进了氨排放;土壤铵态氮含量、土壤孔隙含水量、0~5 cm地温和温室气温均对氨排放通量有...
zh-cn
pair_30994290
Based on a two-year field experiment located at Shenyang Applied Ecological Experiment Station of Chinese Academy of Sciences, we examined the effects of stabilized N fertilizer combined with straw returning on rice yield and emission of N<sub>2</sub>O and CH<sub>4</sub> in aquic brown soil. Six treatments were set up,...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
以中国科学院辽宁沈阳农田生态系统国家野外科学观测研究站连续两年的试验平台为依托,以潮棕壤为供试土壤,开展了稳定性氮肥配合秸秆还田对水稻产量及N<sub>2</sub>O和CH<sub>4</sub>排放的影响研究,设置对照(CK)、尿素(U)、尿素+脲酶抑制剂+硝化抑制剂(U+I)、秸秆还田(S)、秸秆还田+尿素(S+U)、秸秆还田+尿素+脲酶抑制剂+硝化抑制剂(S+U+I)6个处理.结果表明: 与CK相比,尿素显著提高了水稻产量、N<sub>2</sub>O和CH<sub>4</sub>累积排放及全球增温潜势.硝化抑制剂和脲酶抑制剂与尿素配施可显著减缓N<sub>2</sub>O的累积排放.秸秆还田显著增加了N<sub>2</su...
zh-cn
pair_30994292
A field experiment was conducted to investigate the greenhouse gas emission at high latitude farmland in Northeast China. We monitored the greenhouse gas emission using the static chamber-gas chromatography method. Four nitrogen (N) fertilizers were used: conventional N fertilization (CN), slow release fertilizer (SLN)...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为探明不同氮肥条件下高纬度农田土壤的温室气体排放特性,采用静态箱-气相色谱法研究了常规施氮(CN)、施用缓释肥(SLN)、尿素添加硝化抑制剂和脲酶抑制剂(NIUI)、不施氮肥(NN)对东北春玉米农田土壤温室气体排放的影响.结果表明: CN、SLN和NIUI处理产量分别为9618、9376和9645 kg·hm<sup>-2</sup>.与CN处理相比,SLN促进了玉米生长季土壤N<sub>2</sub>O的排放,降低了非生长季土壤N<sub>2</sub>O的排放;NIUI处理N<sub>2</sub>O累积排放量比CN降低了39.0%;各处理土壤CO<sub>2</sub>周年累积排放通量无显著差异;东北春玉米田是大气中CH<su...
zh-cn
pair_30994295
To explore the rational fertilization mode to improve the availability of soil phosphorus (P), we analyzed the changes and coupling characteristics of soil carbon (C) and P, microbial biomass C (MBC) and P (MBP) under different fertilization modes with a successive 22-year field experiment in yellow paddy soil. The exp...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
本研究以进行了22年的黄壤稻田长期定位试验为依托,分析了不同施肥模式下土壤碳(C)、磷(P)与微生物生物量C(MBC)、P(MBP)的变化及其耦合特征,旨在探讨黄壤地区合理培肥模式以提高土壤磷素有效性.试验包括10个处理,分别为不施肥(CK)、单施氮肥(N)、磷钾配合(PK)、氮钾配合(NK)、氮磷配合(NP)、氮磷钾配合(NPK)、单施有机肥(M)、3种有机无机肥配施(1/4M+3/4NP、0.5MNP、MNPK).结果表明:与不施肥相比,N和NK处理土壤有机碳(TOC)、全磷(TP)、MBC、MBP均有不同程度的降低,施磷处理(PK、NP、NPK)则有不同程度的提升;与不施肥和施用无机肥相比,施用有机肥各处理TOC、MBC、MB...
zh-cn
pair_30994301
A field experiment was carried out in a six-year old 'Fuji3'/M26/Malus hupehensis Rehd. apple with <sup>15</sup>N and <sup>13</sup>C labeled tracers, to understand <sup>13</sup>C assimilation capability and the characteristics of translocation and distribution of <sup>13</sup>C-photosynthate and <sup>15</sup>N to fruit...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
以6年生‘烟富3’/M26/平邑甜茶苹果为试材,采用C、N双标记技术,研究在果实膨大后期用不同尿素浓度水溶液(N 0%、0.6%、1.2%、1.8%、2.4%,分别用CK、N<sub>1</sub>、N<sub>2</sub>、N<sub>3</sub>、N<sub>4</sub>表示)涂抹果实周围20 cm范围内叶片对叶片<sup>13</sup>C同化能力及<sup>13</sup>C光合产物、<sup>15</sup>N向果实转移分配的影响.结果表明: 随着尿素浓度的增加,叶片的叶绿素含量、氮含量、光合速率、山梨醇和蔗糖含量、6-磷酸山梨醇脱氢酶(S6PDH)和蔗糖磷酸合酶(SPS)活性及<sup>13</sup>C同化能力均...
zh-cn
pair_30994304
With the growing concerns on global climate change and food security, low carbon agriculture in food production attracts more attention. Low carbon agriculture needs to balance higher-level crop yields and lower greenhouse gas emission in production process. Improving nitrogen mana-gement may help mitigate greenhouse g...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着对气候变化和粮食安全的的日益认识,低碳农业引起了人们的广泛关注.低碳农业的研究需要综合考虑作物产量和温室气体排放,改进氮肥管理可能有助于减缓作物生产系统的温室气体排放,同时实现对作物稳产甚至高产的需求.本试验利用生命周期法研究了不同施氮量(150、225、300 kg N·hm<sup>-2</sup>)对春玉米-晚稻轮作系统碳足迹的影响.结果表明: 随着氮肥用量增加,两季作物生产过程中温室气体和碳足迹增加.在春玉米生产过程中,氮肥生产和施用引起的温室气体排放对碳足迹贡献最大,占36.2%~50.2%;而在晚稻生产中,甲烷的排放贡献最大,占42.8%~48.0%,并且随氮肥用量增加甲烷排放增加.当氮肥施用量减少25%(225 k...
zh-cn
pair_30994305
We examined the substitution efficiency of agro-chemical input intensity from 2000 to 2016 in China by employing SE-DEA model and Gini coefficient, and analyzed the driving factors of substitution efficiency with Tobit model. The results showed that the comprehensive efficiency and the scale efficiency of substitution ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
采用SE-DEA和空间基尼系数,研究了2000—2016年我国农业化学投入强度替代效率,并运用Tobit模型分析了我国及各地区替代效率的驱动因素.结果表明: 我国农业化学投入强度替代的综合效率和规模效率呈现出“N”字型趋势,纯技术效率则波动上升,替代效率的地区差异明显,东部地区更倚重替代要素的投入规模;各年份全国省域差异最高的是综合效率,其次为纯技术效率,规模效率的区域差异性最小,地区内部省域差异逐渐减小,东部地区省域差异最大;农业化学投入替代效率受农业技术水平、农户收入水平、农业生产结构、农业发展程度和工业化水平的显著影响,各地区受各因素影响差异明显.推动农业化学投入替代效率,要从提高农业化学投入强度替代要素的投入效率、调整农用工...
zh-cn
pair_30997704
Achieving coexistence between large carnivores and humans in human-dominated landscapes (HDLs) is a key challenge for societies globally. This challenge cannot be adequately met with the current sectoral approaches to HDL governance and an academic community largely dominated by disciplinary sectors. Academia (universi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
在人类主导景观中实现人与大型食肉动物的共存, 是全世界面临的一个重要挑战。然而, 目前对人类主导景观的部门管理方法和主要由学科领域主导的学术团体尚不足以应对这一挑战。学术界 (大学及研究组织机构) 应通过促进跨部门合作, 在应对人类主导景观中大型食肉动物保护的社会挑战中发挥更积极的作用, 以实现人类与大型食肉动物共存的主流化。借鉴欧洲、亚洲和南美洲人口与大型食肉动物密集地区的经验, 我们建议学术界应进一步采取可持续发展的原则和方法, 创造制度空间以开展超学科课程和项目;思考所应用的研究方法 (单一学科、交叉学科和超学科) 及其研究成果如何帮助推动有利于主流化的机构改革;另外, 还应与各种机构和利益相关群体合作, 创造新的制度结构, ...
zh-cn
pair_30997704
Achieving coexistence between large carnivores and humans in human-dominated landscapes (HDLs) is a key challenge for societies globally. This challenge cannot be adequately met with the current sectoral approaches to HDL governance and an academic community largely dominated by disciplinary sectors. Academia (universi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Incorporación de la Coexistencia entre Humanos y Carnívoros Mayores por Medio de la Colaboración Institucional Resumen Un reto importante para las sociedades mundiales es lograr la coexistencia entre los carnívoros mayores y los humanos en los paisajes dominados por el hombre (HDL, en inglés). Este reto no puede enfren...
es
pair_30998131
To screen and verify the differentially expressed genes related with aging of bone marrow mesenchymal stem cells (BM-MSCs) in acute myeloid leukemia (AML) patients by bioinformatics, so as to provide new molecular markers for the research and clinical treatment of AML. The gene expression profiling chip related with BM...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
急性髓系白血病患者骨髓间充质干细胞衰老相关基因的生物信息学分析及验证. 通过生物信息学方法筛选急性髓系白血病(AML)患者骨髓间充质干细胞(BM-MSC)衰老相关的差异表达基因并予以验证,为AML的科研和临床提供新的分子标志物。. 应用血液病医院AML患者BM-MSC制作基因表达谱芯片并参考从NCBI数据库GEO中选取的芯片GSE84881,综合地进行数据分析并筛选差异表达基因。运用DAVID分析软件进行基因本体论(GO)富集分析和KEGG通路富集分析,筛选出与AML患者BM-MSC衰老相关的差异表达基因。收集病人及健康供者的骨髓样本,体外扩增MSC并应用RT-PCR技术检测衰老相关基因表达水平与芯片的一致性,辅以衰老相关β-半乳糖...
zh-cn
pair_30998132
To investigate the role of bone marrow vascular niche in the development of MLL-AF9 acute myeloid leukemia (AML). Transplantation experiments were performed to establish non-radiated MLL-AF9 AML model; the half-bone immunofluorescence staining and tile-scan imaging of two-photon confocal microscopy were used to obtain ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
骨髓血管微环境在MLL-AF9急性髓系白血病发病中的作用. 探讨骨髓血管微环境在MLL-AF9急性髓系白血病发病过程中的作用。. 应用移植实验构建未照射MLL-AF9急性髓系白血病模型;利用half-bone免疫染色方法和双光子共聚焦多层多通道多视野成像技术,获取骨髓血管、骨内膜和巨核细胞的图像数据;应用流式细胞术分析不同解剖部位白血病细胞的特性。. 在MLL-AF9急性髓系白血病发病早期阶段,白血病细胞在股骨干骺端的比例显著高于骨干处;进一步检测凋亡、增殖特性发现,股骨干骺端处的白血病细胞凋亡比例明显低于骨干区,且细胞增殖(S/G<sub>2</sub>/M期)也明显比骨干区活跃,提示不同解剖部位处白血病细胞的这些特性可能与不同的...
zh-cn
pair_30998133
To investigate the changes of T lymphocyte subsets, B lymphocyte and NK cells in peripheral blood of patients with acute leukemia at different periods and their significance. The peripheral T lymphocyte subsets and B lymphocyte of 95 patients with acute leukemia [(43 cases of acute lymphoblastic leukemia (ALL), 52 case...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
急性白血病患者T、B淋巴细胞的检测与分析. 探讨不同类型的急性白血病患者外周血T淋巴细胞亚群、B淋巴细胞和NK细胞等在疾病的不同时期的变化及其临床意义。. 采用流式细胞术检测95例初诊白血病患者[急性淋巴细胞白血病(ALL)43例,急性髓系白血病(AML)52例]诱导治疗前后及50例正常对照者外周血T淋巴细胞亚群、B淋巴细胞、NK细胞及Treg细胞百分比。. 初诊白血病各组CD3<sup>+</sup>、CD3<sup>+</sup>CD4<sup>+</sup>、CD3<sup>+</sup>CD8<sup>+</sup>、NK细胞阳性率和CD4<sup>+</sup>/CD8<sup>+</sup>比值均明显低于正常对照组(P<...
zh-cn
pair_30998134
To analyze the molecular markers associated with occurrence, development and poor prognosis of acute myeloid leukemia (AML) by using the data of GEO and TCGA database, as well as multiomics analysis. The transcriptome data meeting requirements were down-loaded from GEO database, the differentially expressed genes were ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
急性髓系白血病患者预后不良相关基因的多组学分析. 利用GEO数据库和 TCGA数据库的数据,通过多组学分析方法分析与急性髓系白血病(acute myeloid leukemia,AML)发生、发展及不良预后相关的分子标志物。. 从GEO数据库下载符合要求的转录组数据,运用R语言Limma程序包进行差异表达基因的筛选,并对差异表达基因进行GO功能富集分析和 KEGG 通路富集分析,同时使用STRING数据库数据,利用Cytoscape软件构建蛋白质相互作用网络,筛选出hub gene,结合TCGA 数据库附带的临床信息对hub gene进行预后分析。. 共筛选出620个差异基因,上调的差异表达基因162个,下调的差异表达基因458个。...
zh-cn
pair_30998137
To investigate the clinical biological characteristics and prognosis of the patients with mixed phenotype acute leukemia with t(9;22)(q34;q11.2) and/or BCRABL1 (Ph<sup>+</sup> MPAL). The morphological, immunological, cytogenetic, and molecular features of 33 in patients with Ph<sup>+</sup> MPAL were retrospectively ana...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Ph阳性混合表型急性白血病的临床研究. 分析Ph染色体和/或BCR-ABL1<sup>+</sup>混合表型急性白血病(Ph<sup>+</sup> MPAL)的临床、生物学特征及预后。. 依据欧洲白血病免疫分型协作组(EGIL)的积分系统和WHO2008诊断标准回顾性判断并总结2002年6月至2016年6月收治的33例Ph<sup>+</sup> MPAL患者资料,分析骨髓细胞形态学、 免疫表型、 细胞遗传学和分子生物学等特点。采用急性淋巴细胞白血病(ALL)化疗方案或兼顾髓系、 淋系的联合化疗方案,部分患者治疗期间加用酪氨酸激酶抑制剂(TKI),5例在缓解期进行异基因造血干细胞移植。. Ph<sup>+</sup> MPAL男性...
zh-cn
pair_30998138
To investigate the safety and efficacy of autologous peripheral blood hematopoietic stem cell transplantation (auto-PBHSCT) using modified BU/CY conditioning regimen for young AML patients of low and middle risk in the first complete remission (CR1). Ten young AML patients of low and middle risk who did not want to acc...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
应用改良BU/CY方案预处理联合自体外周血造血干细胞移植治疗青年中、低危急性髓系白血病疗效观察. 观察青年中、低危急性髓系白血病(AML)在第1次完全缓解期(CR1)接受白消安(BU)/环磷酰胺(CY)改良方案预处理后行自体外周血造血干细胞移植(auto-PBHSCT)的安全性及疗效。. 采用回顾性分析方法探讨改良BU/CY预处理联合auto-PBSCT的疗效。本院2013年5月至2016年12月期间10例青年中、低危AML患者,无异基因干细胞移植条件、CR1期接受以改良的BU/CY方案预处理联合auto-PBSCT,移植后3个月开始白介素-2(IL-2)或IL-2+二盐酸组胺维持治疗18个月。观察预处理方案的毒副作用、造血恢复时间...
zh-cn
pair_30998139
To investigate the clinical features, accompanying gene mutation characteristics and prognostic factors of adult patients with acute myeloid leukemia with mutated NPM1 (NPM1<sup>+</sup>AML). Seventy-three patients with newly diagnosed adult NPM1<sup>+</sup>AML were selected. The mutations of 22 genes were detected by s...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
NPM1高突变负荷是NPM1阳性急性髓系白血病患者的预后不良因素. 探讨NPM1基因突变阳性成人急性髓系白血病(NPM1<sup>+</sup>AML)患者的临床特征、伴随基因突变特征及影响预后的因素。. 收集并应用第二代测序法测定22种AML常见的基因突变中NPM1基因突变阳性初诊成人AML患者73例,用实时荧光定量PCR法测定43种AML常见的融合基因,应用Kaplan-Meier生存曲线和Cox多因素回归分析影响预后的因素。. 73例NPM1<sup>+</sup>AML患者中,共检测到74个NPM1基因位点突变,其发生率分别为L287fs(92.0%)、Q289fs和W288fs(2.7%)、L258fs和Q289H(1.4...
zh-cn
pair_30998142
To investigate the effects of mangiferin on proliferation, apoptosis and cycle of FLT3-ITD mutation-positive acute myeloid leukemia cells and its mechanism. The effects of different concentration of mangiferin on proliferation of MV4-11 cells were detected by CCK8 method. Apoptosis, cell cycle and FLT3 transmembrane pr...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
芒果苷对FLT3-ITD突变阳性急性髓系白血病细胞MV4-11增殖的影响及其机制研究. 探讨芒果苷对FLT3-TD突变阳性急性髓系白血病细胞增殖、凋亡周期的影响及其机制. 应用CCK8法检测不同浓度芒果苷作用不同时间对MV4-11 细胞增殖的影响;应用流式细胞术检测细胞凋亡、细胞周期及FLT3跨膜蛋白的表达;应用实时荧光定量聚合酶链反应 (PCR)检测 FLT3 mRNA的表达. 芒果苷对白血病细胞MV4-11具有明显抑制作用,且呈浓度效应关系(48 h,r=0.922;72 h,r=0.959;96 h,r=0.973);不同浓度芒果苷作用MV4-11细胞48 h时,观察到细胞周期内G0/G1期比率升高, S期比率下降,且随芒果苷...
zh-cn
pair_30998143
To investigate the efficacy, prognosis and safety of decitabine combined with low-dose CAG regimen in the treatment of elderly patients with acute myeloid leukemia (AML). The clinical data of 40 elderly patients with relapsed/refractory AML (69-85 years old) admitted to our hospital from January 2014 to August 2016 wer...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
地西他滨联合低剂量阿糖胞苷治疗老年复发/难治性急性髓系白血病患者的疗效、预后及安全性分析. 探讨地西他滨联合低剂量CAG化疗方案治疗老年复发/难治性急性髓系白血病(acute myeloid leukemia,AML)患者的疗效、预后及安全性. 回顾性分析本院在2014年1月至2016年8月收治的40例老年复发/难治性AML患者(69-85岁)的临床资料,根据治疗方案不同分为联合治疗组和对照组,各20例。联合治疗组采用地西他滨联合低剂量CAG方案(地西他滨,15 mg/m<sup>2</sup>,d 1;阿克拉霉素,10 mg/m<sup>2</sup>,d 3-6;注射用阿糖胞苷,10 mg/m<sup>2</sup>,d 1-1...
zh-cn
pair_30998145
To study the effect of traditional chinese medicine (TCM) compound on myeloid leukemia cells and to explore its anti-leukemic mechanism. Myeloid leukemia cell lines were cultured in vitro and treated with TCM compound. The proliferation of the leukemia cells was measured by CCK8 method. The differentiation of the leuke...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
复方中药制剂对急性髓系白血病细胞诱导分化与增殖的作用. 研究复方中药制剂对白血病细胞的作用及其机制. 用复方中药制剂处理体外培养的髓系白血病细胞株,用CCK8的方法观察中药制剂对白血病细胞增殖的影响,瑞氏染色法观察细胞形态学的变化,流式细胞术检测细胞凋亡并测定细胞表面分化抗原CD11b的表达水平. 与单纯的4种白血病细胞系HL-60, MOLM-13,MV4-11,AML-M5相比较,不同中药浓度处理的这4种白血病细胞增殖能力减弱(P<0.05)且其增殖抑制作用呈剂量依赖性(r=0.9236;r=0.7488;r=0.8889;r=0.8119);与单纯的HL-60和AML-M5白血病细胞系相比,药物处理的这2种白血病细胞有明显的分...
zh-cn
pair_30998146
To investigate the effect of targeting the silent information regulator 2 hemolog 2 (SIRT2) expression on the apoptosis of drug-resistant AML cell line HL-60/A and its mechanism. The expression of SIRT2 and antophagy-related protein LCT, P62 in HL-60/A and HL-60 was detected by Western blot, the effect of cytorabine on...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
SIRT2通过自噬机制逆转HL-60/A耐药性的研究. 探讨靶向沉默信息调控因子2同源蛋白2(SIRT2)表达对急性髓系白血病(acute myeloid leukemia,AML)耐药细胞株HL-60/A凋亡的影响及其潜在机制. 采用Western.blot分别检测HL-60/A及对药物相对敏感的亲代细胞株HL-60中SIRT2及自噬相关蛋白LC3、P62的表达。采用siRNA转染HL-60/A细胞,靶向抑制SIRT2表达后,采用Annexin V/PI双染法检测阿糖胞苷对HL-60/A细胞细胞凋亡的影响;采用Western blot和透射电子显微镜检测HL-60/A细胞的自噬影响。为明确自噬在SIRT2对HL-60/A耐药调节中...
zh-cn
pair_30998147
To investigate the expression change of ROCK1 gene in patients with acute lymphoblastic leukemia (ALL) and its prognostic significance. Sixty patients with ALL were selected in our hospital from April 2017 to April 2018, and 60 healthy persons subjected to physical examination were selected as control. The venous blood...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
急性淋巴细胞白血病患者ROCK1基因表达水平变化及其临床意义. 研究ROCK1基因在急性淋巴细胞白血病(ALL)患者中的表达变化及其临床预后意义. 选择自2017年4月-2018年4月在本院接受治疗的60例ALL患者,同时选取60例健康体检者作为对照,从受试者静脉取血后分离单个核细胞,采用RT-PCR实验检测样本的ROCK1基因表达水平,采用Western blot实验检测ROCK1蛋白表达水平,统计学分析ROCK1基因表达与ALL患者临床特征的相关性. ALL患者ROCK1基因相对表达水平为1.37(1.28-1.46),对照组ROCK1基因相对表达水平为1.06(0.96-1.12),ALL患者ROCK1基因水平显著高于对照组(...
zh-cn
pair_30998148
To determine the significance of morphology of bone marrow smear for diagnosis of bone marrow involvement in patients with diffuse large B-cell lymphoma (DLBCL), and to study the morphological characteristics of DLBCL cells involved in bone marrow. Four hundred and twenty cases of DLBCL diagnosed at Peking Union Hospit...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
形态学在弥漫性大B细胞淋巴瘤骨髓侵犯诊断中的作用. 确定骨髓涂片形态对弥漫性大B细胞淋巴瘤(DLBCL)骨髓侵犯诊断的作用,并研究骨髓中DLBCL细胞的形态学特征. 分析北京协和医院于2006年~2016年间确诊的420例DLBCL。应用盲法分析骨髓涂片和骨髓穿刺活检的结果. 骨髓涂片(S)发现42例,骨髓活检(B)发现47例,两者共计(S+B)发现49例骨髓侵犯,2种诊断DLBCL骨髓浸润的方法之间有良好相关性(κ=0.889)。骨髓中DLBCL细胞的形态特征为中等大小、圆形或不规则的细胞核;染色质呈深紫红色和粗颗粒状,多数为1-5个核仁;胞浆量适中,呈深蓝色或灰蓝色,常见空泡和伪足. 骨髓细胞形态学检查在诊断DLBCL骨髓侵犯方...
zh-cn
pair_30998149
To investigate the clinical manifestation, immunophenotypes and prognostic factors of patients with primary tonsil afftive large B cell lymphoma ( PT-DLBCL ). The clinical data including clinical characterstics, typing, staging, treatment efficacy and prognostic factors of PT-DLBCL patients were collected and analyzed ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
原发扁桃体弥漫大B细胞淋巴瘤37例临床分析. 总结原发扁桃体弥漫大B细胞淋巴瘤(PT-DLBCL)的临床特征、免疫表型及预后因素. 收集2009年10月至2018年2月初诊的37例PT-DLBCL患者临床资料,包括临床特征、分型、分期、疗效及预后,并进行回顾性分析. 37例中男性22例(59.5%),女性15例(40.5%),中位年龄57(16-86)岁。能明确细胞起源的36例患者中,生发中心B细胞(GCB)型占66.7%,非生发中心B细胞(non-GCB)型占33.3%。Ann Arbor分期Ⅰ期占40.5 %,Ⅱ期占59.5%,无Ⅲ、Ⅳ期患者。中位随访时间44(10-101)月,2例患者(5.4%)失访。中位治疗6(3-8)个疗...
zh-cn
pair_30998153
To analyze the prognostic value of BCL-2, BCL-6 and MYC in patients with diffuse large B cell lymphoma (DLBCL). One hundred and sixty three cases of DLBCL in our hospital from March 2012 to March 2015 were selected. The specimens of lymphoma tissue of patients were collected. The expression of BCL-2, BCL-6 and MYC was ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
MYC、BCL-2和BCL-6检测在弥漫性大B细胞淋巴瘤患者预后判断中的价值. 分析BCL-2、BCL-6和MYC检测在弥漫性大B细胞淋巴瘤(DLBCL)患者中预后判断中的价值. 收集2012年3月至2015年3月本院收治的DLBCL患者163例患者的淋巴瘤组织标本,采用免疫组织化学方法检测患者BCL-2、BCL-6和MYC的表达水平,并用间期荧光原位杂交技术对IGH/BCL-2融合、BCL-6基因断裂及MYC基因断裂进行检测,进一步分析BCL-2、BCL-6和MYC表达水平与DLBCL患者临床病理特征及预后的相关性. MYC、BCL-2及BCL-6均呈现棕黄色或棕褐色的阳性信号,其中MYC主要于细胞膜上呈现阳性表达,BCL-2主要...
zh-cn
pair_30998152
To investigate the expression of miR-155 in patients with diffuse large B-cell lymphoma (DLBCL), and to explore the effect of transfection of miR-155 inhibitor on the biological characteristics of DLBCL cells. A total of 76 patients with DLBCL treated in our hospital were selected from April 2013 to December 2017. In t...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
miR-155在弥漫大B细胞淋巴瘤组织中的表达及其对细胞生物学特性的影响. 探讨miR-155在弥漫大B细胞淋巴瘤(DLBCL)组织中的表达,以及转染miR-155抑制物对DLBCL细胞生物学特性的影响. 选取2013年4月至2017年12月在本院接受治疗的DLBCL患者76例,同时选取因淋巴结反应性增生就诊的40例患者作为对照组。取2组患者组织标本。培养DB细胞并将其分为miR-155抑制物组、阴性对照组和空白组。使用实时荧光定量PCR技术检测DLBCL组和对照组组织及细胞中miR-155的表达;应用MTT法检测细胞的增殖能力,流式细胞术检测细胞凋亡情况;Transwell法检测细胞迁移和侵袭能力. DLBCL患者组织中miR-1...
zh-cn
pair_30998155
To evaluated the effect of curcumin on the bortezomib-resistant myeloma cells and the expression of Notch1 signaling pathway, in order to further explore its potential mechanism. Curcumin, bortezomib, and curcumin combined bortezomib were added into RPMI 8266, U266, 5 nmol/L bortezomib-resistant RPMI 8266 (RPMI 8226-V5...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
姜黄素通过抑制Notch1信号通路增强多发性骨髓瘤对硼替佐米的化疗敏感性. 探讨姜黄素对耐硼替佐米的骨髓瘤细胞的作用以及对Notch1信号通路表达的影响,进一步探索其潜在的作用机制。. 分别将姜黄素、硼替佐米及姜黄素+硼替佐米作用于骨髓瘤细胞系RPMI8266、U266、耐5 nmol/L硼替佐米的RPMI 8266(RPMI8226-V5R)、耐5 nmol硼替佐米的U266(U266-V5R)及骨髓瘤CD138+浆细胞,应用MTT法检测细胞增殖活性,流式细胞术检测细胞凋亡,Western blot检测凋亡相关蛋白的表达;利用notch1抑制剂DAPT及RNA干扰技术抑制细胞内notch1表达,重复上述实验。. 与单药组相比,联合...
zh-cn
pair_30998156
To investigate the significance of detecting serum complement C3 and C4 in patients with multiple myeloma (MM) and to explore its correlation with myeloma bone disease (MBD). The levels of serum complement C3 and C4 in 69 MM patients and 30 healthy people were examined by scatter nephelometry. The bone density of L1-4 ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
血清补体C3、C4在多发性骨髓瘤患者中检测的意义. 研究血清补体C3、C4在多发性骨髓瘤(MM)患者中的检测意义,并探讨其与骨髓瘤骨病(MBD)的相关性. 采用散射比浊法定量分析69例初诊MM患者以及30例健康体检者血清补体C3、C4水平;采用双能骨密度仪(DXA)测量69例初诊MM患者以及30例健康体检者的正位L1-4椎体、双侧股骨颈、双侧髋关节的骨密度值. MM患者组血清补体C3、C4水平明显高于对照者(P<0.01);ISS临床分期中进展期患者的血清补体C3、C4水平明显高于稳定期患者(P<0.01);在不同MBD分组中,分级C级的补体C3、C4水平明显高于A级和B级(P<0.01);MM患者血清补体C3、C4表达水平与其L1...
zh-cn
pair_30998159
To study the value of neutrophil/lymphocyte ratio (NLR) in the evaluation of prognosis of patients with multiple myeloma (MM). NLR was calculated on the basis of the blood routine examination results of 65 patients with primary MM (MM group) and 83 persons receiving physical examination as control group, and the differ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
中性粒细胞/淋巴细胞比值在多发性骨髓瘤患者预后中的意义. 探讨中性粒细胞/淋巴细胞比值(NLR)对多发性骨髓瘤(MM)患者预后评估的价值. 以65例初发MM患者和83例同期健康体检者,根据血常规结果计算得出NLR,比较2者差异;并以中位数为临界值,将病例组患者分为低NLR组(NLR<2.34)和高NLR组(NLR≥2.34),分析2组患者在年龄、性别、血清钙(Ca)、血清β<sub>2</sub>微球蛋白(β<sub>2</sub>-MG)、白蛋白(Alb)、血肌酐(Cr)、血红蛋白(Hb)、红细胞分布宽度(RDW)及乳酸脱氢酶(LDH)水平的差异;比较高NLR组和低NLR组患者生存率的差异;单因素及COX多因素回归分析各指标与MM...
zh-cn
pair_30998160
To systematically evaluate the efficacy and safety of DCAG regimen for treating the intermediate or high risk MDS and AML. PubMed, EMbase, The Cochrane Library, WanFang Data and CNKI databases were searched to collect randomized controlled trials (RCTs) of decitabine combined with CAG regimen for intermediate or high r...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
地西他滨联合CAG治疗中、高危骨髓增生异常综合征及急性髓系白血病的疗效与安全性的Meta分析. 系统评价地西他滨联合CAG方案(DCAG方案)治疗中、高危MDS及AML的临床疗效及安全性. 计算机检索PubMed、EMbase、The Cochrane Library、WanFang Data 和 CNKI 等数据库,搜集DCAG方案对比地西他滨单药方案或CAG方案治疗中、高危MDS及AML的随机对照试验(RCT),检索时限从建库至2018年3月。所纳入RCT依据 Cochrane 风险偏倚评价工具进行质量评价,采用RevMan 5.3进行Meta分析, 结果共纳入24个RCT,包括1 557例中、高危MDS及AML患者,其中594...
zh-cn
pair_30998161
To explore the potential pathogenetic mutations of primary hypereosinophilia(HEN)by sequencing FGFR1 FLT3, MPL and JAK2 genes, and to clarify their effect on clinical manifestation and prognosis of HEN patients. The direct DNA sequencing was employed to detect the gene mutations of FGFR1, FLT3, MPL and JAK2 in HEN pati...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
原发性高嗜酸粒细胞增多症患者基因突变检测. 通过检测原发性高嗜酸粒细胞增多症患者FGFR1、FLT3、MPL及JAK2基因突变的情况,初步探讨其在该疾病发病机制中的作用及对病情严重程度和患者预后的影响. 应用直接测序法检测原发性高嗜酸粒细胞增多症患者是否存在FGFR1基因、FLT3基因、MPL基因和JAK2基因的突变. 在1例临床症状严重且治疗无效的患者检测到FLT3基因酪氨酸激酶活性区域新的缺失突变,该突变导致编码区提前结束;在19例患者中发现了FGFR1基因新的单核苷酸多态性(SNP)位点,该SNP导致2个氨基酸的缺失;未检测到MPL基因和JAK2 V617F基因突变. FGFR1基因6个碱基的缺失(1014_1019del A...
zh-cn
pair_30998162
To investigate the effects of low-dose decitabine on levels of soluble CD44 and GDF11, and hematopoietic function in elderly patients with myelodysplastic syndrome (MDS). Ninety-nine patients with senile myelodysplastic syndrome (MDS) admitted to our hospital from October 2015 to October 2017 were divided into group A,...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
低剂量地西他滨对老年MDS患者可溶性CD44、GDF11水平及造血功能的影响. 探讨低剂量地西他滨对老年骨髓增生异常综合征(MDS)患者血清可溶性CD44与GDF11水平及造血功能的影响. 2015年10月至2017年10月本院收治的老年骨髓增生异常综合征(MDS)患者99例,随机分为A、B、C 3组,每组各33例。A组采用低剂量地西他滨治疗,B组采用常用剂量地西他滨治疗,C组采用低剂量地西他滨联合G-GSF、阿糖胞苷、阿克拉霉素治疗。治疗结束后,比较3组患者治疗前、后血清可溶性CD44,GDF11水平和造血功能指标(sTfR/E)变化情况,分析3组患者临床缓解率及不良反应发生率. 治疗前,3组患者血清可溶性CD44、GDF11以及...
zh-cn
pair_30998163
To investigate the efficacy and safely of DAC and CAG/HAG preexcitation chemotherapy regimens for the treatment of patients with MDS-RAEB (refractory anemia with excess blasts, RAEB). The clinical data of 86 MDS-RAEB patients were analyzed retrospectively from February 2014 to February 2018. According to therapeutic re...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
两种预激化疗方案治疗MDS-RAEB患者的临床疗效对比研究. 探讨地西他滨(DAC)和CAG/HAG预激化疗方案治疗骨髓增生异常综合征(MDS)难治性贫血合并原始细胞增多(RAEB)的疗效及其安全性的差异. 回顾性分析本院2014年2月- 2018年2月收治MDS-RAEB患者共86例临床资料。在86例中41例采用DAC方案,设为A组,而其余45例采用CAG/HAG方案,设为B组;比较2组的疾病控制效果、起效疗程、中位生存时间及不良反应的发生率. 2组患者CR率和ORR率比较差异无显著性(P>0.05);A组mCR率显著高于B 组(P<0.05);A组第2、3疗程显效病例数显著多于B组,但第1疗程显效的病例数在B组多于A组(P<0....
zh-cn
pair_30998164
To explore the symptomatic burden of patients with essential thrombocythemia (ET) and its relation with clinical characteristics including the mutation status, therapeutic protocols and sex. Total of 173 Chinese ET patients were selected and grouped on the basis of disease characteristics (mutation status, therapeutic ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
173例中国原发性血小板增多症患者的症状负荷评估. 探讨中国原发性血小板增多症(essential thrombocythemia,ET)患者的症状负荷与临床特征(突变状态,治疗方案,性别差异)的关系,为其治疗和预后判断提供依据. 使用骨髓增殖性肿瘤总症状评估量表(MPN-SAF-TSS或MPN 10)对173例中国ET患者进行现场和网络症状评估,根据突变状态将患者分为JAK2V617F突变阳性组,CALR突变阳性组,非三阴性组;根据治疗方案将患者分为羟基脲(Hu)治疗组和干扰素(IFN-α)治疗组;根据性别将患者分为男性患者组和女性患者组。结合症状评分回顾性分析患者的病例资料. 各组患者均表现出由低至高的症状负荷,其中Hu治疗组患...
zh-cn
pair_30998166
To explore the role of neutrophil-to-lymphocyte ratio(NLR) in patients with newly diagnosed essential thrombocythemia(ET) and its relationship with thrombotic events. The clinical and follow-up data of 150 ET patients were retrospectively analyzed. The risk factors of thrombotic events and role of NLR by statistical me...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
原发性血小板增多症患者初诊初治时外周血粒淋比与血栓事件关系研究. 探讨初诊初治时中性粒细胞/淋巴细胞比值(NLR)对原发性血小板增多症(ET)患者血栓事件发生和进展的影响及临床意义。. 回顾性分析150例原发性血小板增多症患者临床和随访资料,用统计学方法分析血栓事件的危险因素。. 年龄(P=0.001) 和JAK2V617F突变(P=0.003)是诊断时血栓事件独立危险因素;年龄(P=0.037)、NLR(P<0.001)、WBC计数(P=0.047)及初诊时血栓病史(P=0.036)是随访过程中未来血栓事件进展的独立危险因素;ROC曲线表明,NLR对于血栓事件进展诊断效能要明显高于年龄、WBC计数以及初诊时血栓病史。Kaplan-...
zh-cn
pair_30998167
To explore whether the high risk factors possibly leading to hypercoagulative status and thrombosis exist in Thalassemia patients of Guangxi region through detecting plasma tissne factor-bearing microparticles (TF<sup>+</sup>MP), procoagulatima activity, coagulation and anticoagulation function, fibrinolytic function, ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
地中海贫血患者组织因子微粒促凝活性及抗凝血酶Ⅲ检测的意义. 通过检测地中海贫血患者血浆组织因子微粒(TF<sup>+</sup>MP)的促凝活性、凝血及抗凝物、纤溶功能、内皮细胞功能及血小板(Plt)计数,探讨广西地区地中海贫血患者是否存在可能引起血液高凝状态及血栓形成的高危因素。. 对71例地中海贫血组及20例正常对照组分别用发色底物法检测血浆TF<sup>+</sup>MP促凝活性,ELISA法检测血浆组织因子(TF)、组织因子途径抑制物(TFPI)、蛋白C(PC)、蛋白S(PS)、抗凝血酶Ⅲ(AT-Ⅲ)、组织型纤溶酶原激活物(t-PA)、凝血酶激活的纤溶抑制物(TAFI)、可溶性E选择素(sE-sel)、细胞间粘附分子-1(s...
zh-cn
pair_30998168
To investigate the gene mutation types and distribution features of α- and β-thalassemia in reproductive population of Xing bin district of Guangxi Lai bin city so as to provide the scientific basis for formulating the preventive and control measures. The high risk population with thalassemia in 6 498 people of child-b...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
920例地中海贫血基因突变类型分析. 探讨广西来宾市兴宾区育龄人群α和β地中海贫血的基因突变类型及分布特征,为制定防治措施提供科学依据. 对2017年1月至2017年12月就诊于本院产前保健科6 498例当地育龄人群采用血细胞五分类和血红蛋白电泳分析指标筛查地中海贫血高危人群,对高危人群采用跨越断裂点的聚合酶链式反应(Gap-PCR)技术和PCR结合反向点杂交(PCR-RDB)技术诊断并分析α、β地中海贫血阳性病例的基因突变类型及其频率. 地中海贫血初筛阳性1 432例,初筛阳性率为22.04%,基因诊断确定为地中海贫血基因阳性920例,阳性率为14.16%。在920例中检岀α-地中海贫血593例(64.45%),基因突变类型 19...
zh-cn
pair_30998169
To establish the reference intervals of the hematological parameters in normal adult people of Xuzhou erea. The red blood cells (RBC), platelets, white blood cells (WBC) and related parameters were detected by hematoanalyzers in 82514 healthy people including 41257 males and 41257 females in the Medical Center of the A...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
中国徐州地区成人血细胞分析参考区间调查和建立. 建立徐州地区正常成人血细胞参数的参考区间. 在徐州医科大学附属医院体检中心应用血细胞分析仪,检测正常人群(男性41 257人, 女性41 257人,共82 514人)静脉血红细胞计数、血小板计数、白细胞计数等相关参数. 各项参数的参考区间如下:红细胞计数(RBC)在男性为(4.33-5.51)×10<sup>12</sup>/L,在女性为(3.82-4.85)×10<sup>12</sup>/L;血红蛋白水平(Hb)在男性为(132-172)g/L,在女性为(107-145)g/L;红细胞压积(HCT)在男性为(40-50)%,在女性为(34-44)%;血小板计数(Plt)在男性为(1...
zh-cn
pair_30998170
To investigate the feasibilily of screening and identifying the red blood cell type alloantibodies by means of surface plasman resonance(SPR) technique so as to provide a new method for detecting the transfusion compatibility of red blood cells. The RBC antigens for screening the alloantibody were fixed on the SPR chip...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
SPR技术在红细胞血型同种抗体筛选与鉴定中的应用研究. 探讨利用表面等离子体共振(Surface plasman resonance,SPR)技术对红细胞血型同种抗体筛选与鉴定的可行性,为红细胞输注相容性检测提供一种新方法. 采用氨基偶联法在SPR芯片表面固定红细胞抗原谱,优化芯片分析条件,检测红细胞血型抗体阳性对照血清,分析SPR芯片技术的检测性能;对比研究SPR芯片技术与微柱凝集法检测129例长期输血的地中海贫血患者临床样本的一致性;同时运用SPR芯片技术对7例血型抗体阳性患者输血前进行血型抗体鉴定,选择红细胞抗原相容性血液输注;跟踪评价红细胞输注效果. SPR芯片技术检测血型同种抗体的重复性、敏感性与特异性均较好;SPR技术与...
zh-cn
pair_30998171
To explore the metabolic characteristics and metabolic markers of WBC-depleted RBCs in MAP preservation solution and to analyzed the metabolic profile of RBC in MAP preservation solution by using metabolomics. The changes of metabolitcs in 10 U WBC-depleted RBC suspension at 3-different storage period (D 0, D 14 and D ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
基于UPLC-MS/MS的去白细胞的悬浮红细胞不同储存阶段代谢特征研究. 采用代谢组学的研究方法,分析红细胞在MAP保存液中不同储存阶段的代谢特征,探索红细胞在MAP保存液中的代谢标志物. 运用超高效液相色谱-四级杆飞行时间串联质谱(UPLC-MS/MS)技术检测10袋MAP去白细胞的悬浮红细胞在制备当天(d 0)、储存第14 d(d 14)、储存期末(d 35)等3个不同储存阶段红细胞内和上清液中的代谢物变化情况,采用主成分分析法(PCA)分析不同储存时间的红细胞差异性特征离子和代谢标志物. 红细胞内和上清液中提取物在存储初期、中期和末期3个储存阶段检测到的特征离子数能够得到明显区分。乳酸、烟碱胺、葡萄糖、5-羟脯氨酸和苹果酸等5...
zh-cn
pair_30998172
To explore the application of blood screening method based on chemiluminescence immunoassay(CLIA)and to evaluate its officacy. Screening HBsAg, anti-HCV, anti-HIV and TP was performed on 3,530 voluntary blood donors by ELISA and CLIA, and then all the specimens with ELISA<sup>-</sup> and ELISA<sup>+</sup>/CLIA<sup>-</s...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
化学发光免疫分析试验在血液筛查中的应用及评价. 探讨基于化学发光的免疫分析试验在血液筛查中的应用及效果评价. 对3530例无偿献血者标本应用ELISA法和CLIA法试剂分别筛查HBsAg、抗-HCV、抗-HIV和TP,然后对HBsAg、抗-HCV和抗-HIV ELISA法阴性全部标本和ELISA<sup>+</sup>/CLIA<sup>-</sup>标本再应用NAT进一步复检;对ELISA法和CLIA法TP单阳性以及双阳性标本采用TPPA法进一步确证. CLIA法与NAT法检测结果的一致性较好,较ELISA法检测重复性好,灵敏度高;对于CLIA<sup>+</sup>/ELISA<sup>-</sup>标本,ELISA法存在漏检结...
zh-cn
pair_30998173
To study the association between IL-10 gene-592(C→A) (rs1800872) single nucleotide polymorphism (SNP) and the graft versus host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in children. Ninety-seven childhood patients and seventy-one donors in the Hematology Oncology Center of Bei...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
IL-10基因-592(C→A)位点单核苷酸多态性与儿童异基因造血干细胞移植后移植物抗宿主病的相关性研究. 研究IL-10基因-592(C→A)位点(rs1800872)单核苷酸多态性(single nucleotide polymorphism, SNP)供者和受者基因型对儿童异基因造血干细胞移植(allo-HSCT)后移植物抗宿主病(graft versus host disease, GVHD)的影响. 对2011年1月至2017年7月在首都医科大学附属北京儿童医院血液肿瘤中心进行异基因造血干细胞移植的97例儿童患者及与之配对的71例供者进行基因型检测。提取外周血基因组DNA,采用TaqMan SNP Genotyping A...
zh-cn
pair_30998174
To investigate the injury effect of anti-donor specific antibody (DSA) on human umbilical vein enolothelial cells (HUVEC) in NK-mediated antibody-dependent cell cytotoxity (ADCC). The peripheral blood of 10 healthy donors was colleced for allo-HSCT of AML patients diagnosed in Department of Hemology of the Tumor Hospit...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
DSA对NK细胞介导ADCC效应中血管内皮细胞损伤的影响. 探讨抗供者特异性抗体(DSA)在自然杀伤细胞(NK)介导抗体依赖细胞介导的细胞毒效应(ADCC)对人脐静脉内皮细胞(HUVEC)损伤作用。. 收集10名健康供者为山西医科大学附属肿瘤医院血液科确诊为AML拟行allo-HSCT的患者提供的外周静脉血,并分离提取外周血NK细胞为效应细胞。选取培养至4-6代HUVEC与DSA共培养,将结合DSA的HUVEC作为靶细胞(CDH组),未结合DSA的HUVEC作为阴性对照(UDH组);将效应细胞与靶细胞共培养后通过流式细胞仪检测细胞因子干扰素-γ(IFN-γ)表达,应用MTT法检测HUVEC细胞活性,间接反映DSA介导ADCC效应对内...
zh-cn
pair_30998175
To screen the antioxidant small molecular compounds with optimal efficiency of expansing the human hematopoietic stem cells (hHSC) In vitro based on antioxidant small molecular compound database of LKT laboratory, and to verify the effects of these compounds on the biological functions of hHSC. The umbilial cord blood ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
抗氧化小分子化合物体外扩增人造血干细胞的筛选和验证研究. 基于LKT实验室抗氧化小分子化合物库,筛选人造血干细胞(HSC)体外扩增效果最佳的小分子化合物,并初步验证其对人HSC生物学功能的影响。. 采用MACS磁珠富集脐带血CD34<sup>+</sup>细胞,体外加药培养1周后应用BD Fortessa高通量流式细胞术检测CD34<sup>+</sup>细胞及CD34<sup>+</sup> CD49f<sup>+</sup>细胞的绝对数和比例,以SR1 (1 μmol/L)为阳性对照,筛选出多个候选化合物。对候选化合物浓度、安全系数、扩增效果等多方面因素进行综合考量后,选出C2968、D3331、B1753、B3358 4个化合...
zh-cn
pair_30998176
To investigate the effect of microvascular endothelial cells (MEC) on the proliferation of hematopoictic stem cells (HSC) under different culture conditions in vitro. The MEC from lung tissue of C57BL/6 mice and the HSC from bone marrow of GFP mice were used for non-contact co-culture, 2 D contact co-culture, at same t...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
在不同培养条件下微血管内皮细胞对骨髓造血干细胞增殖影响的比较. 探讨在体外不同培养条件下微血管内皮细胞(microvascular endothelial cells, MEC)对骨髓造血干细胞(hematopoietic stem cells, HSC)增殖的作用. 将来源于C57BL/6小鼠肺组织的MEC与来源于GFP小鼠骨髓的HSC用于非接触共培养、2 D接触共培养,并设置对照组HSC单独培养及MEC单独培养。采用细胞计数和CCK8实验比较各组悬浮细胞在1、3、5和7 d的增殖情况. MEC呈贴壁生长。HSC共培养组及单独培养组细胞在体外培养过程中悬浮细胞计数均有所增加;2 D接触培养组与非接触共培养组中悬浮细胞比对照组中悬...
zh-cn
pair_30998179
To explore the blood transfusion data of emergency hemorrhage patients, so as to provide the basis for improving the quality of emergency blood transfusion and guiding clinic rational blood transfusion. one thousand emergency blood loss patients once transfused RBC suspension were collected by Recipient Epidemiology an...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
急诊失血患者的临床用血情况分析. 探究急诊失血患者相关用血资料,为提高急诊输血质量和指导临床合理用血提供依据. 通过REDS-Ⅲ“临床用血研究”项目,收集本院2012年11月-2015年11月输注红细胞悬液的1 000例急诊失血病例,对年龄、性别、病因、输血前体征、血液检测指标、是否手术、血液制品输注量和预后情况等相关指标进行了回顾性分析,并根据红细胞悬液输注量将患者分为低输注量组(<5 U)、中输注量组(5-10 U)和高输注量组(>10U),通过单因素分析及Logistic多因素回归分析,对输血预测指标和死亡的危险因素进行统计分析. 高输注量组在性别、病因、收缩压、血红蛋白水平、是否手术、血液制品输注量、ICU滞留时间、总住院时...
zh-cn
pair_30998180
The explore the molecular basis of iron-overload in Tibet nationality population of Tibet. The inpatients with iron-overload in our department from Dec. 1st 2014 to Jul.31st 2016 were enrolled in this study. Abdominal MRI and the mutation sites C282Y and H63D in HFE exon were examined. For HFE mutation-negative patient...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
西藏藏族铁过载患者HFE基因及非HFE基因的突变研究. 探讨西藏藏族人群铁过载的分子基础。. 筛选自2014年12月-2016年7月在我科住院治疗的西藏藏族居民,选取其中存在有铁过载的患者,行腹部MRI及HFE基因位点C282Y、H63D检测,对有HFE突变阴性的患者,再进一步行非HFE基因常见突变位点的检测,包括HJV基因的G320V、p.Q312X、p.D249H、p.I281T、p.C321X,TFR2基因的Y250X和I238M及SLC40A1基因的V162del、N144H。. 全部113人行HFE基因位点C282Y、H63D检测中,仅发现1例p.H63D纯合型和10例p.H63D杂合型;在同意行非HFE基因检测的73例患...
zh-cn
pair_30998181
To study the distribution of monoclonal gammopathy of undetermined significance(MGUS) in different age, sex and ethnic people over 40 years old. Five hundred and ninety-six people(over 40 years old) examened in the Health Examination center of the First Affiliated Hospital of Xinjiang Medical University from July 2017 ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
40岁以上人群中意义未明单克隆免疫球蛋白血症的发病情况分析. 了解40岁以上人群中意义未明单克隆免疫球蛋白血症(MGUS)在不同年龄、性别、民族的分布情况及危险因素。. 收集2017年7月到2017年9月在新疆医科大学第一附属医院健康体检中心健康体检596人(年龄≥40岁,男性310例,女性286例,汉族488例,维吾尔族108例)。根据年龄将健康体检人群分为40-59、60-79和≥80岁3组,记录所有人的年龄、性别、族别。首先采用毛细管血清蛋白电泳对所有样本筛查,如果电泳图谱发现疑似单克隆条带,再进行血清免疫固定电泳明确蛋白类型。. 596例被筛查人群中MGUS发病24例(4.027%),40-59、60-79和≥80岁组人群M...
zh-cn
pair_30998182
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used in the treatment of hematological diseases, HLA incompatibility is displayed in most cases. Some patients have prestored donor-specific antibodies (DSA) or new emerging antibodies after transplantation. Donor-specific antibodies may cause gra...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
供者特异性抗体在异基因造血干细胞移植中的研究进展. 异基因造血干细胞移植(allo-HSCT)被广泛应用于治疗各种血液系统疾病,HLA不全相合的造血干细胞在allo-HSCT中较为常见。部分患者移植前或移植后存在供者特异性抗体,此类抗体可能引起植入失败和造血恢复延迟等移植并发症,影响患者的移植效果。识别供者特异性抗体的高危人群并对高危人群进行抗体检测,对于抗体阳性的患者进行及时的干预对于改善HLA不全相合造血干细胞移植的效果有重要意义。本文就供者特异性抗体流行病学、风险因素、供者特异性抗体对于非亲缘供者及单倍体相合HSC供者的allo-HSCT的影响、供者源的抗HLA抗体对于移植的影响以及供者特异性抗体的脱敏治疗做一综述。.
zh-cn
pair_31001824
In psychosocial migration literature, the perspective of ambiguous loss has been relevant to articulate personal and relational experiences in the context of transnational families and ongoing separation. Most studies have focused on adult members' experiences of transnational families, but research exploring ambiguous...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
在关于移民的心理社会学问题的文献中,模糊性失落被用于解释在跨国家庭和长期分离状况下的个体体验和个体与他人的关系的亲历体验。大多数研究都集中在跨国家庭中成年家庭成员的经历,关于青少年中因为父母移居不在身边而导致的模糊性失落的研究还非常欠缺。本研究旨在探索那些家长已移民的青少年的人生经历。初步的探索性研究中有14名青少年参加访谈,他们中至少有一个家长移居不在身边。访谈的内容主要是关于跨国亲子关系的亲历体验和长期性的亲子分离经历。对参与者的叙述进行数据分析后得出四个主要的主题:分离这种亲子关系实践造成困惑;移居离家的父母和其孩子之间的关系的现状充满着模糊性;孩子讲述已移居离家的家长时表露出对他们的不信任感;家庭的动态关系和社交性方面的动力...
zh-cn
pair_31001824
In psychosocial migration literature, the perspective of ambiguous loss has been relevant to articulate personal and relational experiences in the context of transnational families and ongoing separation. Most studies have focused on adult members' experiences of transnational families, but research exploring ambiguous...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
En la bibliografía sobre las consecuencias psicosociales de la migración, la perspectiva de la pérdida ambigua ha sido relevante para expresar las experiencias personales y relacionales en el contexto de las familias transnacionales y la separación constante. La mayoría de los estudios se han centrado en las experienci...
es
pair_31001941
The emergence and spread of antimicrobial resistance has become a serious global issue. Bacterial characteristics, such as antimicrobial resistance genes, virulence-associated genes, plasmid types, and phylogenetic relationship among different strains, are the keys to unravel the occurrence and dissemination of antimic...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着耐药细菌的大量出现及广泛传播,细菌耐药性成为全球备受关注的问题。耐药细菌的特征如耐药基因、毒力因子、质粒分型等以及不同菌株间亲缘关系对于细菌耐药性流行病学及分子生物学的研究有着十分重要的意义。但是传统的技术手段如聚合酶链式反应 (Polymerase chain reaction,PCR) 和脉冲场凝胶电泳 (Pulsed field gel electrophoresis,PFGE) 等得到的结果不够全面且精确度低,对于现有的研究存在很大的局限性。全基因组测序技术 (Whole genome sequencing,WGS) 和生物信息学分析 (Bioinformatics analysis) 由于能够快速详尽地得到耐药细菌的特...
zh-cn
pair_31001942
Bacterial biofilm refers to a tunicate-like biological group composed of polysaccharide, protein and nucleic acid secreted by bacteria on the surface of the mucous membrane or biological material. The biofilm formation is a major cause of chronic infections. Bacteria could produce some secondary metabolites during the ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
细菌生物被膜 (Bacterial biofilm,BF) 是黏附于机体黏膜或生物材料表面、由细菌及其分泌的多聚糖、蛋白质和核酸等组成的被膜状生物群体,是造成持续性感染的重要原因之一。细菌在生长繁殖时会产生一些次级代谢产物,部分会作为生物信号分子在细胞内或细胞间传递信息,使细菌在多细胞水平协调统一相互配合,以完成一些重要的生理学功能,如生物发光、BF 的形成、运动与固定态生活方式的转换等。信号分子在BF 形成过程中起着重要的调控作用。文中从密度感应系统 (Quorum-sensing systems,QS)、环二鸟苷酸(Cyclic diguanylate,c-di-GMP)、双组分系统 (Two-component systems...
zh-cn
pair_31001943
Ethyl carbamate (EC), a carcinogenic and teratogenic chemical that is widely distributed in various alcoholic beverages, has attracted much attention. Microbial enzymatic degradation of EC in rice wine is always efficient and attractive. In this review, we summarize the research progress and problems of microbial enzym...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
氨基甲酸乙酯 (Ethyl carbamate,EC) 具有致癌性,广泛存在于酒精饮料中。我国的黄酒因EC 含量高而带来的食品安全问题越来越受到人们的关注。微生物酶法消除黄酒中的EC 具有直接、高效的特性而被深入研究。文中从黄酒中EC 的形成机制、酸性脲酶研究现状、氨基甲酸乙酯水解酶研究现状等方面概述了微生物酶法消除黄酒中EC 的研究进展及存在的问题。并针对这些问题,提出了寻找新型氨基甲酸乙酯水解酶、Fe³⁺依赖型双功能酸性脲酶食品级表达与定向进化及双酶并用将尿素和EC 一起消除的策略。.
zh-cn
pair_31001944
Baculovirus expression vector system (BEVS) has been successfully applied to the over-expression of various proteins, thus providing sufficient materials for vaccine research. Compared to other systems, BEVS has many advantages: baculovirus solely being parasitic in invertebrates, the resultant products conferring high...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
昆虫杆状病毒表达载体系统 (Baculovirus expression vector system,BEVS) 已成功应用于多种蛋白的表达,并为疫苗开发提供了充足的原材料。相比其他表达系统,BEVS 具有许多优势:杆状病毒专一寄生于无脊椎动物,安全性高;重组蛋白表达水平高;可对重组蛋白进行正确折叠和翻译后修饰,获得具有生物活性的蛋白;适应于多基因表达如病毒样颗粒 (Virus-like particle) 的复杂设计;适用于大规模无血清培养等。为了更好地理解BEVS 在疫苗研究中的应用前景,文中将从BEVS 的发展及其在疫苗研究中的应用等方面进行综述。.
zh-cn
pair_31001945
Sclerotinia sclerotiorum is a typical necrotrophic plant pathogenic fungus that distributes worldwide and causes severe diseases on a broad-range of plant species. Studies on S. sclerotiorum have been mainly focused on biology and pathology. The development of high-throughput technologies enabled multi-omics approaches...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
None
zh-cn
pair_31001946
Long non-coding RNAs (lncRNAs) are members of RNA that are structurally similar to mRNA. They cannot encode proteins because they do not have a conserved open reading frame. LncRNAs were once regarded as abnormalities or noises or without any biological function after gene transcription. With the further development of...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
长链非编码RNA (Long non-coding RNA,lncRNAs) 是RNA 的其中一员,其结构类似于mRNA,但由于没有保守的开放阅读框,因此不能编码蛋白质。LncRNAs 曾被认为是基因转录后的异常现象或噪音,没有任何的生物学功能。随着研究的进一步深入,发现其可作为重要的调控分子参与人类正常或异常的生物学活动过程。LncRNAs 与神经系统功能、机体代谢紊乱以及肿瘤等疾病的发生发展密切相关。异常表达于宫颈癌的lncRNAs 通过发挥抑制肿瘤或促进肿瘤的作用,参与调控宫颈癌的各个生物学过程。文中结合最新报道就lncRNAs 在宫颈癌的异常调节、分子调节机制和潜在临床应用方面进行综述。.
zh-cn
pair_31001947
Isopeptide bond-mediated molecular superglue is the irreversible covalent bond spontaneously formed by the side chains of lysine (Lys) and asparagine/aspartic acid (Asn/Asp) residues. The peptide-peptide interaction is specific, stable, and can be achieved quickly without any particular physicochemical factor. In the l...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
异肽键分子粘合剂是多肽链中的赖氨酸 (Lys) 残基和天冬酰胺或天冬氨酸 (Asn/Asp) 残基侧链自发结合形成的不可逆共价键,具有良好的特异性和稳定性。该反应可在极短的时间完成,且不需要特定的理化环境和催化剂。文中结合近年来国内外学者对异肽键分子粘合剂的研究进展,综述了异肽键分子粘合剂的来源、类型、形成机制及其介导的分子环化和蛋白拓扑结构,并讨论了其在合成疫苗、水凝胶和细菌纳米生物反应器等领域的应用前景。.
zh-cn
pair_31001948
Glucoamylase is a critical ingredient for saccharification in the starch decomposition, and widely used in food, pharmaceutical and fermentation industries. Glucoamylases are usually thermostable and have peak activities at high temperature, as required for the industrial process of glucose production. In this study, a...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
葡萄糖淀粉酶作为淀粉糖化的关键用酶之一,广泛应用于食品、医药和发酵工业等行业。由于整个制糖过程都是在高温下完成的,因此对葡萄糖淀粉酶的反应温度和热稳定性有较高要求。本研究从嗜热篮状菌Talaromyces leycettanus JCM12802 中克隆到一个糖苷水解酶第15 家族 (GH15) 葡萄糖淀粉酶基因 (Tlga15A) 并在毕赤酵母GS115 中实现异源表达。重组葡萄糖淀粉酶TlGA 的最适pH 为4.5,在75 ℃下表现出最高酶活。TlGA热稳定性好,65 ℃条件下处理1 h 剩余70%以上酶活力;70 ℃处理30 min 后仍有43%酶活力。TlGA 有较强的离子抗性和宽泛的底物特异性,TlGA 水解可溶性淀粉、支...
zh-cn
pair_31001952
Cordyceps militaris exopolysaccharides (EPS) have many pharmacological activities such as boosting immunity and antifatigue. To obtain EPS efficiently, we added moderate Vernonia amygdalina leaf powder as inducer to the fermentation medium to promote the production of Cordyceps militaris EPS and studied the infrared ab...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
蛹虫草胞外多糖具有增强免疫力、抗疲劳等药理活性,有极高的保健价值。为高效地获取蛹虫草胞外多糖,本研究通过向发酵培养基中添加适量的扁桃斑鸠菊叶粉末,来提高蛹虫草发酵液中胞外多糖的产量,并对优化得到的胞外多糖红外吸收光谱和化学抗氧化活性进行了研究。实验结果表明,液体发酵最优条件为:扁桃斑鸠菊叶粉末添加量8 g/L、发酵时间9 d、pH 6.5、接种量5.0 mL,在此条件下,蛹虫草胞外多糖的产量可达(5.24±0.28) mg/mL,与未添加扁桃斑鸠菊叶的空白组相比,胞外多糖产量提高了约205.20%;红外分析与抗氧化活性实验结果显示,扁桃斑鸠菊叶对蛹虫草生产的胞外多糖结构和活性影响较小。该研究结果表明扁桃斑鸠菊叶能够有效地提高蛹虫草胞...
zh-cn
pair_31001954
In order to provide a theoretical basis for better understanding the function and properties of proteins, we proposed a simple and effective feature extraction method for protein sequences to determine the subcellular localization of proteins. First, we introduced sparse coding combined with the information of amino ac...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
文中提出了一种简单有效的蛋白质亚细胞区间定位预测方法,为进一步了解蛋白质的功能和性质提供理论基础。运用稀疏编码,结合氨基酸组成信息提取蛋白质序列特征,基于不同字典大小对得到的特征进行多层次池化整合,并送入支持向量机进行分类。经Jackknife 检验,在数据集ZD98、CH317 和Gram1253 上的预测成功率分别达到95.9%、93.4%和94.7%。实验证明基于多层次稀疏编码的分类预测算法能显著提高蛋白质亚细胞区间定位的预测精度。.
zh-cn
pair_31001955
Endogenous peptides, in the form of cytokines, growth hormones and hormone peptides, play an important role in human hormones, nerves, cell growth and reproduction. Neuropeptide is a kind of endogenous peptide, which is related to the physiological activities of pain, sleep, emotion, learning and memory. Neuropeptides ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
内源性肽以细胞因子、生长激素、激素肽等形式在人体的内分泌、神经、细胞生长和生殖各个领域发挥功能。神经肽是一种内源性肽,与痛觉、睡眠、情绪、学习与记忆等生理活动相关,不但存在于脑部神经细胞,也存在于其他体液和器官内并发挥重要作用。目前对器官内源性肽的研究仍不足,尤其是其中的神经肽。文中应用液质联用串联质谱高通量鉴定胰腺、心脏、肝脏和肾脏中内源性肽的分布以及神经肽的种类。鉴定结果显示,在肝脏中内源性肽和神经肽的数目最多,而胰腺中最少;所鉴定到的内源性肽具有器官特异性,在4 个器官中分别呈现不同的动态分布;4 个器官中神经肽的LPV (最长肽变异体) 数目差异较大,而且基因家族的分布也各不相同,比如胰腺中的神经肽多属于Glucagon 家...
zh-cn
pair_31001957
Multi-epitope recombinant diagnostic antigen (designated 'B102') of Mycobacterium tuberculosis (Mtb) was prepared and evaluated as a serological diagnostic antigen. With TRX at the N-terminal and His tag at the C-terminal, the multi-epitope Mtb recombinant diagnostic antigen including 11 predicted B-cell epitopes from ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
将结核分枝杆菌 (Mycobacterium tuberculosis,Mtb) 多个B 细胞预测表位串联表达 (命名为B102),并初步评价其作为诊断抗原的血清学诊断价值。将Mtb PstS1、ESAT6、CFP10、Ag85B、Ag85A 及PPE54 等6 个蛋白的11 个B 细胞预测表位串联,加入合适的连接臂后全基因合成;将多表位片段插入带有TRX 标签的表达质粒中,在大肠杆菌BL21 (DE3) 中诱导表达,并利用Ni²⁺-Chelating 亲和层析和DEAE 阴离子交换层析纯化目的蛋白;利用Western blotting (WB) 技术对目的蛋白抗原性进行鉴定,并建立Mtb 抗体检测竞争法ELISA 技术,初步评价此...
zh-cn
pair_31001958
Yeast autolysis under solid-state fermentation can effectively promote the release of various active substances, thereby improving the quality of yeast products. The optimal process for yeast autolysis under solid-state fermentation was obtained by optimizing the autolysis temperature, autolysis time and the zinc ion c...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
固态下酵母自溶可以有效促进菌体内多种活性物质的释放,进而提高酵母类产品的品质。通过优化自溶温度、自溶时间及自溶促进剂锌离子浓度以获得固态发酵下酵母自溶的最佳工艺,对固态发酵物料中游离氨基酸、可溶性蛋白、α-氨基氮含量和A₂₆₀/A₂₈₀ 等指标的分析来确定固态酵母自溶工艺条件,在此基础上以自溶温度40 ℃、50 ℃、55 ℃;作用时间12、18、24 h;锌离子添加浓度2、4、8 mg/kg 设置L₉(3³)正交试验,进一步优化固态酵母自溶的工艺参数。结果表明酵母自溶的最佳工艺条件为:自溶温度55 ℃、作用时间18 h、锌离子浓度2 mg/kg,此时其可溶性蛋白含量可达9.31 mg/g、游离氨基酸14.36 mg/g、α-氨基氮1...
zh-cn
pair_31006193
Recent years, national laws and government policies were published as series to encourage the development of group standardizations. The updated Standardization Law of the People's Republic of China, implemented on January 1(st), 2018, stipulates that group standard is a part of the Chinese standard system. Under the c...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
近年来我国对团体标准的法律和政策供给力度不断加大,出台了一系列鼓励支持团体标准发展的政策措施。2018年1月1日起实施的新《标准化法》正式赋予了团体标准法律地位,团体标准正式成为了我国标准体系的一部分。在良好的法律和政策环境支持下,越来越多的社会团体积极参与到制定发布团体标准中来。团体标准虽然呈现迅猛发展的势头,但目前仍处在探索和逐步规范的阶段。本文通过总结中华预防医学会团体标准化工作的发展和实践情况,分析我国团体标准化工作现状和不足,并提出了推动和规范团体标准发展的对策和建议。.
zh-cn
pair_31006212
With the accelerated urbanization process, there are growing interests in the potential impact of neighborhood built-environment on residents' physical activity and dietary habits. In this paper, we introduced the concept of the built environment and the ways to assess the built-environment related to physical activity...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
社区建成环境对居民身体活动、饮食行为的影响越来越受到关注。本文对建成环境的概念以及身体活动、饮食行为相关建成环境的评价方法做了概述,对近年来国内外身体活动、饮食行为与建成环境的关联研究现状和主要结果进行了综述。分析表明,改善建成环境有望控制身体活动不足和不健康饮食行为流行带来的健康负担,但该领域尚处于初步探索阶段,仍有很多尚待回答的研究问题。通过对已有研究可能存在的问题进行总结,本文对今后的研究提出了建议。.
zh-cn
pair_31006213
Depression jeopardizes human health and brings heavy burden to both related families and societies. However, pathogenesis of depression has not been fully clarified yet. Previous studies show that there are some connections seen between dietary factors and depression, which are affected by various lifestyles. This pape...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
抑郁症严重威胁人类健康,给社会和家庭带来了沉重的负担,但其发病机制尚未明确。研究发现膳食与抑郁症存在一定关联,而且不同的生活方式对抑郁症的影响不尽相同。本文通过对既往文献进行综述,探讨营养素、膳食模式和生活方式等与抑郁症的关系,为抑郁症的防治提供一定的依据。.
zh-cn
pair_31006214
Along with the significant development on both theory and practice of health promotion programs, the application of behavioral and social science theories has also been advanced in the fields of design and evaluation regarding the intervention-related studies. Intervention mapping is a new planning protocol, efficientl...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着健康促进理论和实践研究的快速发展,社会行为科学理论被更多地应用于干预措施的设计和评价。干预图是近几十年来新出现的一种指导健康促进干预设计、实施和评估的方法,在不少健康问题干预研究中取得良好的应用效果。本文简要介绍干预图方法的基本概念、实施步骤、具体要求以及此方法在妇幼健康促进、慢性病管理和传染病防控等方面的应用,为国内健康干预研究提供参考。.
zh-cn