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pair_31603589
Long-term studies to understand biodiversity changes remain scarce-especially so for tropical mountains. We examined changes from 1911 to 2016 in the bird community of the cloud forest of San Antonio, a mountain ridge in the Colombian Andes. We evaluated the effects of past land-use change and assessed species vulnerab...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Extirpaciones de Aves y las Dinámicas Comunitarias en un Bosque Nuboso Andino durante más de Cien Años de Cambios de Uso de Suelo Resumen Los estudios a largo plazo para entender cambios en la biodiversidad todavía son escasos - especialmente en las montañas tropicales. Examinamos los cambios en la comunidad de aves de...
es
pair_31605564
Male obesity is suggested to impact negatively on male fertility and semen quality in numerous studies. However, previous literatures regarding health effects of the metabolic syndrome (MetS) on semen quality are rare and inconsistent. The aim of this study is to investigate the relationship between MetS and sperm para...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
背景: 许多文献指出肥胖对于男性生殖能力及精液的品质有负面影响, 然而, 有关代谢症候群对于精子品质影响的研究结果有限且不一致。本研究旨在在台湾生育年龄的男性人群中探讨代谢症候群与男性精液品质的相关性。 方法: 2010-2016年期间于一家健检中心接受健康检查的8395名男性的资料纳入这横断面研究。根据国际卫生组织准则进行精子品质的分析, 包括浓度、总活动力、前进运动和正常精虫型态。代谢症候群的诊断根据美国国家胆固醇教育发表的胆固醇治疗方案(National Cholesterol Education Program Third Adult Treatment Panel)以及亚洲腰围修正版本的定义。利用多元线性回归分析代谢症候群...
zh-cn
pair_31606995
Congenital facial palsy is unilateral or bilateral facial nerve palsy at birth due to genetic or different pathogenic factors. It can be divided into syndromic type and non-syndromic type according to its accompanying symptom. The pathogeny and symptom of each type are different, in part with genetic heterogeneity. Con...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
None
zh-cn
pair_31607009
A rare disease, also referred to as an orphan disease, is defined as the disease with a low prevalence or that affects a small percentage of the population. It is a well model of human disease, which can facilitate the in-depth study and understanding of related diseases. Therefore, five Chinese governmental authoritie...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
罕见病(rare diseases)又称'孤病'(orphan diseases),是指发病率极低、患病人数少的疾病或病变,是人类良好的疾病模型,可促进对相关疾病的深入研究与认识。因此,2018年5月11日国家卫生健康委等五部委联合制定公布了我国《第一批罕见病目录》,共涉及121种疾病,其中具有口腔表征的疾病51种,占42.2%。包括颅面部异常、牙列(齿)异常、口腔软组织病变、颌骨病变、唾液腺相关疾病等,甚至部分为罕见病的首发、早发和必发表现。为强化口腔同行对罕见病目录重要性的认识,阐明口腔医师在罕见病诊治中的重要作用,本文详细阐述了该目录中部分疾病的口腔表征,旨在提高同行对这些疾病的诊治水平,造福患者。.
zh-cn
pair_31607010
With the emergence and development of new dental materials, chairside computer aided design/computer aided manufacture (CAD/CAM) materials, as an important part of digital technology, is gaining increasing progress to meet the needs of implant restorations and digital processing technology for the mechanical properties...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
近年,口腔数字化技术发展迅速,椅旁数字化修复技术因具有高效、精确等优势,逐渐被应用于种植修复领域,成为国际口腔种植专业的前沿技术。在临床需求不断增长、数字化技术进步的推动下,椅旁可切削材料在力学性能、美学性能、化学稳定性、生物相容性及加工性能等方面的研究取得了突破性进展,拓宽了可切削材料的类型,尤其是关于多晶陶瓷、玻璃陶瓷及复合材料等材料性能的研究均成为该领域的研究重点和热点并取得新进展。本文就种植修复中椅旁可切削材料的性能、临床适应证及研究现状进行综述。.
zh-cn
pair_31607011
Depth of invasion is a newly added index for TNM staging of oral cancer in the eighth edition. Preoperative evaluation of depth of invasion not only provides a reference for surgical margin, but also serves as an independent prognostic factor for predicting lymph node metastases. At present, the main methods for assess...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
浸润深度是第八版口腔癌TNM分类分期中新增的指标。浸润深度的评估不仅为手术切缘提供参考,也是预测颈淋巴转移的独立预后因素。目前舌鳞状细胞癌浸润深度主要的评估方法有超声检查、MRI、CT、正电子发射断层成像(positron emission tomography,PET)和病理检查。现对舌鳞状细胞癌浸润深度的评估方法及效果进行概述,并分析其优点及不足,以期为临床应用提供参考。.
zh-cn
pair_31607037
This year of 2019 is the 10(th) anniversary of the 2009 H1N1 influenza pandemic, and a series of paper on epidemiology, disease burden, vaccine usage and adverse events following immunization (AEFI) incidences, cost-effectiveness of influenza vaccination, are forming an important topic of 'influenza disease burden and ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
今年是2009年甲型H1N1流感大流行10周年,本刊组织国内专家编写本期流感疾病负担和疫苗政策重点号,分别报道了近年来我国流感流行病学特征、疾病负担、疫苗应用现状及不良反应、接种成本效果等研究成果,为我国流感防控政策的开发和促进、公众宣传和健康教育提供证据支撑和更有效的选项。我国应持续积极推动促进流感疫苗接种的政策研究,逐步提升重点人群的流感疫苗接种率,提升我国流感防控和大流行防范能力。.
zh-cn
pair_31607038
To implement Healthy China 2030 Plan and Healthy China Actions (2019-2030) requires a high quality and efficient public health care system. Centers for disease prevention and control as one of the important components of the public health care system, should be critically transformed and reformed in their functions. Go...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
《'健康中国2030'规划纲要》和《健康中国行动(2019—2030年)》对建设优质高效公共卫生服务体系提出了更高要求。作为公共卫生服务体系重要组成部分,疾病预防控制机构需要通过功能转型和改革实现更好的发展。政府对新时期疾控机构功能重新定位并法定化,依据其功能完善相应的保障机制和评价机制,以及疾控机构加强自身能力建设等至关重要。.
zh-cn
pair_31607039
Vaccination is the best intervention to prevent influenza and its complications. Effective influenza immunization strategy facilitates influenza vaccine coverage to protect the population and reduce disease burden. This paper analyzes related influenza policies from six countries with high vaccination rates and summari...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
疫苗接种是预防流感及其并发症的最有效手段。有效的流感免疫政策和策略,可显著提高流感疫苗接种率以保护高危人群,降低疾病负担。本文通过分析6个流感疫苗高接种率国家的免疫政策,总结5个共性的关键要素,并基于国内实际情况提出建议策略。.
zh-cn
pair_31607040
Health care workers have higher risk of influenza infection because of their occupational exposure to infected patients. Infection of the health care workers may not only result in the increasing risk of the nosocomial infection and family transmission, but also disrupt the health services due to absence from work. Hea...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
医务人员由于日常工作暴露,罹患流感的风险更高。同时医务人员感染流感病毒可增加院内和家庭传播的风险,由于疾病导致的缺勤还会影响医疗体系的正常运转。全球有40多个国家和地区均将医务人员纳入流感疫苗接种的优先人群。国内调查数据显示医务人员流感疫苗接种率普遍不高。本文主要对国内外流感疫苗的接种政策和现状进行概述,分析探讨符合我国实际的医务人员流感疫苗免疫策略。.
zh-cn
pair_31607055
We analyzed the influenza surveillance data of Children's Hospital of Suzhou University from 2016 to 2018 and estimated the hospitalization burden of children under 5 years old due to influenza infection in Suzhou. The results showed that the influenza virus positive rate of 1 451 severe acute respiratory infection (SA...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
分析2016—2018年苏州大学附属儿童医院的流感监测数据,估算苏州5岁以下儿童因流感而导致的住院负担。结果显示,苏州大学附属儿童医院1 451例严重急性呼吸道感染(SARI)病例的流感病毒阳性率为13.6%(95<i>%CI</i>:11.8%~15.3%;197例);2017—2018年度流感流行强度较高,以A/H1N1为流行株。估算苏州5岁以下儿童流感相关的SARI住院率为6.9‰(95<i>%CI</i>:6.6‰~7.2‰),其中<6月龄儿童住院率较高,为11.4‰(95<i>%CI</i>:9.9‰~12.8‰)。.
zh-cn
pair_31607056
Research participants were recruited at 16 elderly activity centers among three cities in Macao, Hong Kong and Guangzhou. A total of 324 people were surveyed, with women ≥ 55 years old and men ≥ 60 years old; There were 90, 100 and 134 in Macao, Hong Kong and Guangzhou respectively. The median (<i>P</i>(25)<i>, P</i>(7...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
在澳门、香港及广州3个城市的16个老年活动中心招募研究对象。共调查了324名,女性≥55岁、男性≥60岁;澳门、香港、广州分别为90、100、134名。澳门、香港、广州社会支持评定量表得分<i>M</i>(<i>P</i>(25),<i>P</i>(75))分别为30(25,28)、24(20,29)和30(26,37)分,其中澳门、广州老年人的社会支持评定量表得分属中高组的比例(85.20%、84.50%)高于香港(62.10%)(<i>P<</i>0.05)。所处城市、婚姻状况及个人幸福指数与社会支持得分有关。.
zh-cn
pair_31607057
From 2010 to 2014, a total of 17 150 new cases of thyroid cancer (TC) reported in cancer registration areas of Zhejiang province, the crude incidence rate of TC was 29.28/100 000. Using the Chinese Census in 2000 and the World Segi's population as the standard population, the age-standardized incidence rate by Chinese ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2010—2014年浙江省肿瘤登记地区共报告甲状腺癌发病病例17 150例,发病率为29.28/10万,采用2000年中国标准人口和Segi′s世界标准人口的标化率(中标率和世标率)分别为24.11/10万和20.65/10万;共报告甲状腺癌死亡病例256例,死亡率为0.44/10万,中标率为0.23/10万,世标率为0.23/10万。中标发病率呈逐年上升趋势(APC=28.62%,95<i>%CI</i>:21.00%~36.72%,<i>t=</i>13.10,<i>P=</i>0.001),中标死亡率变化较为平稳(APC=0.73%,95<i>%CI</i>:-7.47%~9.66%,<i>t=</i>0.27,<i>P=</...
zh-cn
pair_31607058
Influenza is an acute respiratory infection that seriously harms the world and public health. Because influenza viruses are prone to mutations and difficult to predict, the World Health Organization has been promoting global continuous strengthening of influenza surveillance to monitor the level of influenza activity a...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
流感是严重危害全球和公众健康的急性呼吸道传染病。由于流感病毒容易发生变异,难以预测,WHO一直推动全球持续加强流感监测,以实时监测流感活动水平和流行趋势。通过建立流感流行基线和阈值有助于判断流感疫情的开始和严重程度。目前,计算基线和阈值的方法多样,例如年中位数、百分位数法、移动流行区间法和控制图法等。本文将对检索到的国内外制定流感基线或阈值的方法进行归纳总结,希望为我国流感基线或阈值的制定提供参考依据。.
zh-cn
pair_31607059
Original antigenic sin may exist in the influenza virus infection or vaccination, which possibly reduces the protective efficacy in repeated influenza vaccination. This paper reviews the literature on the original antigenic sin and its influence in influenza vaccination, and interprets the possible mechanism of this ph...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
流感病毒感染或疫苗接种可能存在原始抗原效应,可能会降低重复接种的流感疫苗的保护效果。本文对流感疫苗接种中的原始抗原效应及其影响的文献进行综述,并从流感病毒结构、体液免疫与细胞免疫三个角度解释该现象的可能发生机制。目前有大量研究显示原始抗原效应对流感疫苗的接种产生负面影响,但也有相关不支持该现象的证据,应开展多中心大型临床试验,为研究接种流感疫苗是否存在原始抗原效应及其影响提供循证依据,为新型流感疫苗的研制和更新及其免疫策略的制定提供借鉴和参考。.
zh-cn
pair_31607060
Based on the principle of Joinpoint regression (JPR) model and the additivity of Poisson distribution, this paper constructed a JPR model for series cumulative data. The notifiable incidence number of dengue fever cases per week and weekly cumulative data in Guangdong province from 2008 to 2017 were analyzed, using (me...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
本研究根据Joinpoint回归模型原理和Poisson分布的可加性,构建序列累计和数据Joinpoint回归模型,以广东省2008—2017年登革热周发病数、周累计和发病数为例进行分析,并以均方差(MSE)和平均相对误差绝对值(MAPE)为指标评估模型拟合效果。除2015年外,其他年份基于周累计和发病数的序列累计和数据对数线性Joinpoint回归模型的MSE和MAPE值均小于基于周发病数的对数线性模型。序列累计和数据Joinpoint回归模型拟合精确度较好,可适用于传染病流行趋势变化特征分析和阶段性累计发病数预测。.
zh-cn
pair_31607061
The concern of high myopia in adolescents is increasingly prominent, because of the high prevalence and early onset of myopia in younger children. High myopia increases the risk of various fundus complications, resulting in serious damage to the vision of the working population. The mechanisms underlying the fundus pat...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
随着近视眼高发以及低龄化,青少年高度近视眼问题日益凸显。高度近视眼眼底发生病理性改变的风险增加,其并发症会对视觉质量造成严重影响。高度近视眼眼底并发症的发生机制尚不明确。在近视眼发展过程中,脉络膜变薄可能最先发生,并可能通过影响视网膜和巩膜的血液供应,刺激近视眼向高度近视眼发展,诱发眼底的病理性转变。目前病理性近视眼的治疗方法有限且无法逆转视觉损伤,因此对于高度近视眼眼底并发症需从预防源头做起,以预防近视眼发生、控制近视眼进展以及抑制单纯性高度近视眼病理性转变为主攻方向。本文提出应加强对近视眼病理性演变规律的认识,从而探索建立近视眼眼底病变预警指标体系及高度近视眼健康管理模式,促进早期发现和干预,多管齐下防控高度近视眼眼底并发症的发...
zh-cn
pair_31607068
Pathological myopia refers to high myopia with fundus pathological changes. Choroidal neovascularization is one of its serious complications, and also the main cause of visual loss. Currently, the first-line treatment is anti-VEGF treatment, with good efficacy, high safety, good prognosis, and other advantages of visio...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
病理性近视眼指高度近视眼伴眼底病理性改变,继发脉络膜新生血管是其严重并发症之一,也是导致视力下降的主要因素。目前一线治疗方法是抗血管内皮生长因子(VEGF)治疗,具有疗效确定、安全性高、视力预后较好等优势。常用抗VEGF药物包括贝伐单克隆抗体、雷珠单克隆抗体、阿柏西普、康柏西普。主要治疗方案包括1+ pro re nata(PRN)和3+PRN,临床多以雷珠单克隆抗体治疗病理性近视眼继发脉络膜新生血管的Ⅱ期临床试验提出的标准对再注射进行评估。本文针对抗VEGF治疗的优势、药物选择、治疗方案及再注射标准,对相关研究进展进行综述,以期为临床治疗提供参考。(中华眼科杂志,<i>2019</i>,<i>55</i>:<i>791</i>-<...
zh-cn
pair_31607283
To study the safety and effectiveness of humanized CD19-targeted CAR-T cells (hCART19s) for treatment of patients with refractory/relapsed (R/R) B-ALL. The analyzed patients were 15 children and adults with relapsed/refractory B-ALL who not received treatment with murine CD19 CAR-T cells. The patients received a single...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
人源化抗CD19嵌合抗原受体T细胞治疗急性B淋巴细胞白血病的临床研究. 研究人源化CD19 CAR-T细胞治疗难治/复发性B-ALL患者的安全性和有效性. 入组的患者为15例既往未接受鼠源CD19 CAR-T细胞治疗的复发/难治的 B-ALL儿童和成人患者。患者在氟达拉滨和环磷酰胺为基础的预处理化疗后,接受了1×10<sup>6</sup>/kg的自体人源化CD19 CAR-T(hCART19)细胞的输注。在患者回输CAR-T细胞后观察其治疗的安全性及有效性. 15名患者中,13/14(92.9%)可评价的患者在hCART19输注后30 d获得了完全缓解(CR)或者CR伴血细胞不完全恢复(CRi)。180 d时总生存率及无病生存率分...
zh-cn
pair_31607284
To summarize the clinical characteristics of patients with acute myeloid leukemia-type M<sub>2</sub> (AML-M<sub>2</sub>) and analyze the factors affecting the prognosis. One hundred eighty-eight AML-M<sub>2</sub> patients were retrospectively analyzed for the following parameters including peripheral blood, immune phen...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
188例急性髓系白血病M<sub>2</sub>型患者的临床特征及预后分析. 总结急性髓系白血病 M<sub>2</sub> 型(acute myeloid leukemia-type M<sub>2</sub>,AML-M<sub>2</sub>)患者的临床及实验室特征资料并分析影响预后的因素. 通过回顾性分析本血液病研究中心收治的 188例急性髓系白血病 M<sub>2</sub> 型患者外周血、骨髓象、免疫表型、细胞遗传学及分子生物学等方面的特点,分析影响其总体生存(OS)、无事件生存(PFS)的相关因素. 在188例M<sub>2</sub> 患者中,伴有t(8;21)的染色体核型异常占37%(70/188),染色体核型正常...
zh-cn
pair_31607287
To investigate the effect of chromosomal karyotype on the prognosis of patients with acute promyelocytic leukemia (APL) in condition of the maintenance treatment based on arsenic trioxide. The patients with acute promyelocytic leukemia for last 12 years in our hospital were retrospectively collected. The patients mainl...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
以亚砷酸为主的维持治疗下染色体核型对急性早幼粒细胞白血病患者预后的影响. 探讨在以亚砷酸为主的维持治疗体系下染色体核型对急性早幼粒细胞白血病患者的预后影响. 回顾性收集12年内本院住院治疗的急性早幼粒细胞白血病患者,并选取其中以亚砷酸为主的方案维持治疗且可随访的患者,分为单纯 t (15; 17)组,t (15; 17)伴有附加染色体异常组,正常核型组并探讨附加染色体异常对患者预后的影响,同时进一步探讨复杂核型对预后的意义. 单纯t (15; 17)组患者共57例,早期死亡8例,其早期死亡率为14.0%。附加染色体异常组患者21例,其早期死亡4例,死亡率19.0%。正常染色体组15例,早期死亡5例,其死亡率33.3%, 3组间早期死...
zh-cn
pair_31607288
To investigate the effect of metformin on the proliferation, apoptosis and energy metabolism of acute myeloid leukemia (AML) K562 cells and the possible mechanism. Different doses (0, 5, 10, 20 and 30 mmol/L) of metformin was added into the K562 cells, which were cultivated for 24 h, 48 h and 72 h. The inverted optical...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
二甲双胍对K562细胞增殖、凋亡及糖酵解的影响. 探讨二甲双胍对K562细胞增殖、凋亡及糖酵解的影响及其可能的作用机制. 采用不同浓度二甲双胍(终浓度 0、 5、 10 、20和 30 mmol/L)作用于K562细胞,分别培养24、48 和72 h,倒置光学显微镜下观察细胞生长,应用CCK-8 检测细胞活力,筛选出合适的二甲双胍处理浓度(终浓度 0、10 、20和 30 mmol/L)及最佳作用时间(48 h)进行后续实验。应用Annexin V-FITC/PI双染流式细胞术检测细胞凋亡,葡萄糖和乳酸试剂盒检测葡萄糖消耗和乳酸分泌,采用荧光定量PCR检测糖酵解相关基因表达,采用Western blot法检测蛋白表达. 与对照组比较...
zh-cn
pair_31607289
To investigate effect and mechanism of miR-214 in fludarabine resistance of chronic lympho-cytic leukemia (CLL). A total of 10 patients with CLL resistante to fludarabine (Flu) and 10 healthy persons admitted to Hematology Department of our hospital in August 2014 - July 2018 were selected. Expression level of miR-214 ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
miR-214介导慢性淋巴细胞白血病对氟达拉滨耐药的作用研究. 探讨miR-214在慢性淋巴细胞白血病(CLL)细胞对氟达拉滨耐药中的作用及机制. 选择2014年08月-2018年07月本院血液科收治对氟达拉滨(Flu)耐药的CLL患者和健康受试者各10例,采用RT-PCR法测定单个核细胞中miR-214表达水平。将CLL患者原代细胞分为空白对照组(control group)、阴性对照组(miR-214-NC group)和miR-214转染组(miR-214-ASO group)。转染病毒24 h后与Flu共同培养48 h,测定细胞增殖和凋亡情况,以及PTEN和PI3K/AKT信号通路下游相关基因和蛋白表达水平. CLL患者单个...
zh-cn
pair_31607290
To investigate the mechanism of rapamycin-induced apoptosis of chronic myelogenous leukemia cells. The chronic granulocytic leukemia K562 cells were divided into 3 groups: A, B and C group were treated with rapamycin of 10, 15 and 20 nmol/L, repectively for 24 h, while the K562 cells in control group were not treated w...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
雷帕霉素通过EZH2/Hedgehog信号通路诱导慢性髓系白血病细胞凋亡. 探讨雷帕霉素诱导慢性髓系白血病(CML)细胞凋亡的机制. 对CML细胞K562用雷帕霉素10(A组)、15(B组)和20(C组) nmol/L分别处理24 h,对照组不加雷帕霉素。采用MTT法检测雷帕霉素对K562细胞增殖的影响, AnnexinV-FITC/PI 双染法检测雷帕霉素对K562细胞凋亡的影响, RT-PCR检测雷帕霉素对K562细胞EZH2/Hedgehog信号通路基因表达水平,Western blot检测雷帕霉素对K562细胞凋亡及相关信号通路蛋白表达水平. MTT法检测发现,不同浓度雷帕霉素对细胞增殖有明显抑制作用,其中C组的细胞存活率3...
zh-cn
pair_31607292
To investigate the IL-7R gene mutation and clinical features of adult patients with acute lymphoblastic leukemia (ALL). One hundred sixty-four cases of newly treated adults with ALL from May 2016 to December 2018 were selected. Targeted and specific next-generation sequencing technology was used to detected a total of ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
成人急性淋巴细胞白血病IL-7R基因突变及临床特征分析. 研究成人急性淋巴细胞白血病(ALL)患者IL-7R基因突变及临床特征. 选择2016年5月至2018年12月确诊的初治成人ALL患者164例,采用靶向特异的第二代测序技术检测包括IL-7R基因突变在内的16种Ph-like ALL突变,分析IL-7R基因突变ALL患者的临床特征及IL-7R基因的突变率,发生位点及突变类型. 164例成人ALL患者中,10例患者发生IL-7R突变,突变总频次为13次,突变率6.1%,10例中男性5例(50%),女性5例(50%);B-ALL 6例(占60%),T-ALL 4例(占40%),均位于exon6。置换突变6例,缺失突变3例,插入突变4...
zh-cn
pair_31607293
To investigate the relationship of miR-140 expression level with the therapeutic effect of decitabine, and to explore whether the molecular mechanism is dependent on the regulation of TLR4 expression. Forty-seven patients with acute myeloid leukaemia (AML) were enrolled in our study and divided into decitabine combinat...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
血浆miR-140表达水平与地西他滨治疗疗效的关系及其机制研究. 探讨血浆miR-140表达水平与地西他滨化疗疗效的关系及其具体分子机制是否与对Toll样受体-4(TLR4)表达的调控有关. 急性髓系白血病(acute myeloid leukaemia, AML)病人47例,分别用地西他滨联合化疗方案治疗(22例)和用传统治疗方案治疗(25例),比较2组病人临床疗效,采用实时荧光定量PCR(real-time PCR)检测病人血浆miR-140的表达水平。以地西他滨、miR-140 mimic、miR-140 inhibitor处理体外培养的AML细胞株HL-60,应用real-time PCR及Western blot分别检测H...
zh-cn
pair_31607294
To investigate the efficacy and safety of decitabine combined with half-course pre-excitation for the treatment of elderly patients with acute myeloid leukemia (AML). 44 cases of newly diagnosed elderly AML admitted in our hospital from January 2016 to December 2017 were selected for the retrospective analysis. The pat...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
地西他滨联合半程预激方案治疗老年急性髓系白血病患者的疗效与安全性观察. 观察地西他滨联合半程预激方案治疗老年急性髓系白血病(AML)患者的疗效与安全性. 选择本院2016年1月-2017年12月44例初诊的老年AML患者进行回顾性分析。根据治疗方案将患者分为2组:预激治疗组作为对照(22例)和联合治疗组(22例),前者采用常规全程预激治疗,后者采用地西他滨联合半程预激方案治疗。比较疗效和治疗期间副反应。所有患者均进行随访,比较2组6个月、12个月、24个月的生存率. 联合治疗组RR为72.73%,对照组RR为50.00%,差异有统计学意义(P<0.05)。联合治疗组中位生存时间为17.82±4.19个月,明显优于对照组中位生存时间(...
zh-cn
pair_31607295
To explore the inhibitory effect of dehydrocostus lactone on the proliferation of human chronic myeloid leukemia K562 cells and the underlying mechanisms. Cell viability was evaluated by CCK-8 assay. Flow cytometry was used to assess the effect of dehydrocostus lactone on the cell cycle and apoptosis of K562 cells. The...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
去氢木香内酯对K562增殖的抑制作用及其机制. 探讨去氢木香内酯对慢性髓系白血病细胞系K562细胞的增殖抑制作用及其机制. 应用CCK-8法检测细胞增殖抑制率,采用流式细胞术检测细胞凋亡和细胞周期,Western blot检测相关蛋白的表达. CCK-8检测结果显示,4、6、8、10、12 μmol/ L去氢木香内酯能够明显抑制K562细胞增殖,作用24 h抑制率分别为(24.32±3.05%)、(42.91±3.89%)、(46.35±4.93%)、(77.06±5.42%)、(89.04±4.25%),对照组为 (2.08±0.27%),差异有统计学意义(P<0.05);5、10 μmol/L去氢木香内酯能够诱导K562细胞凋亡...
zh-cn
pair_31607296
To explore the coexisting mutations in IDH-mutated acute myeloid leukemia(AML) and its relation with partial clinical parametrs. The exon 4 mutation of IDH1/2 gene was screened by using genome DNA-PCR combined with sanger sequencing, 51 targeted gene mutations in the patients with IDH1/2 mutation were detected by using...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
急性髓系白血病中与IDH1/2突变共存的基因突变分析. 探讨急性髓系白血病(AML)患者中与IDH1/2突变共存的基因突变及其与部分临床参数的相关性。. 采用基因组DNA-PCR联合Sanger测序法筛选IDH1/2基因4号外显子突变;采用高通量DNA测序联合Sanger测序法检测IDH1/2突变患者51种肿瘤靶基因突变. 358例患者中共检出46例IDH1/2突变,其中35例IDH1突变,11例IDH2突变。97.8%(45/46)IDH1/2突变患者同时携带其他基因突变,其中双基因突变8例,3个基因突变共存17例,≥4个基因突变共存20例。每例患者平均突变3.52次。伴随基因突变中最常见的基因为NPM1(n=29,63.0%),...
zh-cn
pair_31607297
To analyze and investigate the expression levels of HES1, C-MYC and NF-kB in peripheral blood of patients with T cell acute lymphoblastic leukemia (T-ALL) and their significance. Sixty patients with T-ALL and 60 patients with acute myelogenous leukemia (AML) diagnosed in our hospital from June 2012 to March 2015 were e...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
急性T淋巴细胞白血病患者外周血HES1、C-MYC和NF-kB表达水平及其意义. 分析并探讨急性T淋巴细胞白血病(T-ALL)患者外周血HES1,C-MYC和NF-kB表达水平及其意义. 2012年6月- 2015年3月在本院确诊为T-ALL和急性髓系白血病(AML)患者各60例,分别设为T-ALL组和AML组,另30例健康体检人群作为对照组。采集3组外周血,应用RT-PCR法检测HES1、C-MYC、NF-kB表达水平,对比3组一般资料及不同白血病型、细胞遗传学分型、预后患者外周血HES1、C-MYC、NF-kB的表达差异. 3组年龄、性别等基线资料比较无差异(P>0.05)。T-ALL组、AML组血红蛋白(Hb)、白细胞(WBC...
zh-cn
pair_31607300
To investigate the effect of LNK gene silencing and overexpression on the expression of STAT3 gene in human monocytic leukemia cells (THP-1). THP-1 cells were cultured, and the lentivirus was used as a vector to silence and overexpres the LNK gene stably. After transfection for 72 hours, the GFP expression levels were ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
LNK基因沉默和过表达对THP-1细胞STAT3表达影响的研究. 探讨LNK基因沉默和过表达对人单核细胞白血病细胞(THP-1)STAT3基因表达的影响. 培养THP-1细胞;以慢病毒为载体介导SiRNA、LNK(SH2B3)稳定沉默及过表达LNK基因;转染72 h后于倒置荧光显微镜下观察细胞的GFP表达量;应用流式细胞术检测慢病毒感染效率;RT-PCR验证LNK沉默及过表达效应,检测STAT3 mRNA表达量;Western blot检测LNK、STAT3蛋白水平. 慢病毒感染72 h THP-1细胞GFP表达量达85%以上,细胞感染效率在99%以上。LNK沉默组LNK及STAT3 mRNA表达量明显低于对照组,而LNK过表达组的...
zh-cn
pair_31607301
To explore the mechanisms of angiogenesis in chronic myeloid leukemia (CML) through detecting the levels of angiogenesis-related factors secreted from K562 cells after overexpression and interference of HIF-1α gene in K562 cells. The K562 cells were transfected by lentiviruses carried and interfered HIF-1α gene, then t...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
HIF-1α对K562细胞血管生成相关因子的影响. 通过在K562细胞过表达和干扰HIF-1α后检测K562细胞分泌血管生成相关因子的水平,探讨慢性白血病血管生成的机制. 应用携带和干扰HIF-1α基因的慢病毒转染K562细胞,将转染携带和干扰HIF-1α基因的K562细胞分别纳入过表达组、干扰组,同时以空载病毒转染K562细胞纳入对照组。3组细胞在常氧状态下培养72 h后收集细胞,通过荧光显微镜观察3组转染效率,采用RT-PCR法检测HIF-1α和血管相关生成因子mRNA表达水平,ELISA法检测培养上清中血管相关细胞因子的浓度. 慢病毒转染K562细胞最佳转染复数(MOI)为10,转染效率为50%左右;经过嘌呤霉筛选后转染阳性细...
zh-cn
pair_31607303
To investigate the efficacy of multiple protein expressions and clinical features on the threapeutic effect and prognosis of patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL). The clinical data of 68 DLBCL patients were collected and analyzed retrospectively. The clinical staging was performed accordi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
不同蛋白表达及临床特征对弥漫大B细胞淋巴瘤患者预后的影响. 探讨多种蛋白表达及临床特征对初诊弥漫大B细胞淋巴瘤(DLBCL)患者治疗效果的影响. 回顾性分析我院68例初诊DLBCL患者的临床资料,根据Ann Arbor进行临床分期, IPI指数进行危险分级,依B细胞来源分为生发中心来源及非生发中心来源,免疫组织化学检测Ki67、BCL-2、BCL-6、C-MYC、MUM1、CD10等蛋白的表达,根据化疗方案将患者分为R-CHOP组(50例)和CHOP样组(18例),最后根据性别、年龄、红细胞沉降率(ESR)、血清乳酸脱氢酶(LDH)、是否使用利妥昔单抗以及上述临床指标,应用SPSS 22.0软件进行统计学分析影响初诊DLBCL患者的...
zh-cn
pair_31607306
To investigate the expression and significance of LncRNA RP11-513G11.1 in peripheral blood of patients with diffuse large B-cell lymphoma (DLBCL), and to analyze its correlation with clinicopathological features and prognosis of patients. The serum samples of 93 patients with DLBCL(DLBCL group) and 62 normal persons (c...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
LncRNA RP11-513G11.1在弥漫大B细胞淋巴瘤患者外周血中的表达及意义. 探讨LncRNA RP11-513G11.1在弥漫大B细胞淋巴瘤(DLBCL)患者外周血中的表达及意义. 收集93例于西南医科大学血液科确诊为DLBCL(DLBCL组)患者和62例正常人(对照组)血清标本,采用实时荧光定量PCR法检测血清标本中RP11-513G11.1的表达,分析其表达与患者临床病理特征及预后的关系. RP11-513G11.1在DLBCL患者血清中的表达明显高于正常对照组(P<0.001);RP11-513G11.1的表达与患者的年龄、性别、治疗周期及生发中心B细胞淋巴瘤(GCB)亚型无关(P>0.05),而与肿瘤大小、Ann...
zh-cn
pair_31607307
To investigate the tumorigenicity of several multiple myeloma (MM) cell lines transplanted in mice without γ-ray irradiation and to construct the MM disease model to facilitate in vivo experiments. NOD/SCID or NSG mice were subcutaneously or caudally transplanted with MM cell lines (LP-1, OPM2, RPMI 8226 and MOLP8), or...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
不同多发性骨髓瘤细胞系移植小鼠的成瘤情况分析. 探讨在无γ射线照射条件下,几种常见的多发性骨髓瘤(MM)细胞系移植小鼠的成瘤情况,以及构建MM疾病模型便于体内实验研究. 利用MM细胞系LP-1、OPM2、RPMI 8226和MOLP8,以及通过转染带有Luciferase荧光素酶的慢病毒载体得到的RPMI-Luc-Puro(载体带Puromycin抗性基因)、RPMI-Luc-mCherry(载体带mCherry标记基因)和MOLP8-Luc-Puro稳定细胞系,经皮下或者尾静脉植入NOD/SCID或NSG小鼠。观察其肿瘤生长,测量肿瘤大小;应用流式细胞术检测小鼠尾血中CD138<sup>+</sup>肿瘤细胞的比例;应用血清免疫固...
zh-cn
pair_31607308
To retrospectively analyze the cases of multiple myeloma treated with chemotherapeatic regimens based on thalidomide, and to investigate the factors affecting MM patients treated using chemotherapeutic regimens with or without bortezomib. The clinical, laboratorial and survival data of 200 patients with newly diagnosed...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
初诊非造血干细胞移植的多发性骨髓瘤患者预后因素的长期回顾性分析. 对以沙利度胺为基础治疗方案的MM病例进行回顾性分析,探讨含或不含硼替佐米的治疗方法下影响MM患者的预后因素是否不同. 收集本院2007年10月至2015年12月200例初诊MM患者的临床实验室各项指标及活存情况,采用χ<sup>2</sup>检验、t检验、COX回归分析、乘积极限法(Kaplan-Meier)以及Log-rank 检验进行数据处理,分析各项临床实验室指标与MM患者的临床特征和预后的相关性. 多因素分析显示,硼替佐米组中年龄、ISS分期、复杂核型、完全缓解是OS的独立预后因素;传统治疗组中,β<sub>2</sub>微球蛋白(≥8.95 mg/L)和未完...
zh-cn
pair_31607309
To investigate the expression, mechanism and methylation level of miR-28-5p in multiple myeloma (MM), so as to provide the expirement basis for searching new targeted therapy. RT-PCR was used to detect the expression levels of miR-28-5p and potential target CCND1 in CD138<sup>+</sup> cells of the patients with MM and b...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
microRNA-28-5p在多发性骨髓瘤的表达分析与表观遗传学研究. 探讨miR-28-5p在多发性骨髓瘤(MM)中的表达、作用机制及其甲基化水平在MM诊断中的应用,为寻求新的靶向治疗方法提供依据. 采用RT-PCR检测MM患者骨髓单个核CD138<sup>+</sup>细胞和相关疾病对照组(缺铁性贫血患者)骨髓单个核细胞的miR-28-5p及miR-28-5p潜在靶标CCND1的表达水平;甲基化特异性PCR(MSP)检测LPP/miR-28-5p启动子区 CpG岛甲基化水平,并分析与其他临床指标的相关性。用甲基转移酶抑制剂 5-aza-dc对多发性骨髓瘤细胞株U266进行处理,用MSP对药物处理后细胞内LPP/miR-28-5p...
zh-cn
pair_31607310
To investigate the biological characteristics of ABCG2 and its effect on side population cells (SP cells) of multiple myeloma (MM) so as to find the way for reversing drug resistance. The silence of ABCG2 expression was performed throngh interfering the MM cells by using siRNA. then the ratio of SP cell of MM, speed of...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
ABCG2对多发性骨髓瘤侧群细胞及相关通路的作用. 探讨ABCG2的生物学特性及其对多发性骨髓瘤(MM)侧群细胞(side population cells,SP cells)的作用,以探究逆转药物耐药的办法. 利用siRNA干扰多发性骨髓瘤细胞,使ABCG2表达沉默。对比干扰前后多发骨髓瘤侧群(SP)细胞比例、细胞增殖速度、细胞对化疗药物敏感性,进一步了解ABCG2的生物学功能及其在调控多发骨髓瘤侧群细胞及PTEN/PI3K/AKT信号通路发挥的作用. siRNA干扰可以下调ABCG2的表达,干扰后的MM细胞ABCG2在mRNA及蛋白水平上表达明显降低。siRNA干扰后MM细胞增殖能力略有减弱, PTEN表达升高,PI3K/AKT...
zh-cn
pair_31607312
To investigate the phenotype and molecular mechanism of DCA on MDS cell model, and to study the response of chemotherapeutic medicines to MDS cells through multiple dimensions, such as cell proliferation, invasion, migration and apoptosis, thus revealing the molecular mechanism of DCA treatment of MDS and its relations...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
地西他滨抑制SHP-1基因甲基化对MDS细胞株Skm-1增殖及凋亡影响. 探讨DCA作用于MDS细胞模型后的表型及分子机制,通过细胞增殖、侵袭迁移及细胞凋亡等多重维度研究化疗药物作用于MDS细胞后的反应,揭示DCA治疗MDS的分子机理及其与SHP-1基因甲基化的关系. 采用MTT法测定不同浓度DCA处理后的MDS细胞存活率,采用Transwell实验检测DCA对MDS细胞侵袭和迁移能力的影响,应用AnnexinV-FITC/PI法检测细胞凋亡情况,Western blot免疫蛋白印迹和real time PCR实验研究DCA治疗MDS的作用机制. 实验发现,DCA作用于MDS skm-1细胞能抑制肿瘤增殖,且2.0及5.0 μmol...
zh-cn
pair_31607313
To investigate the clinical efficacy and safety of low-dose decitabine (DAC) alone for treatment of myelodysplastic syndrome (MDS) Methods: Fifty-one patients with meddle- and high-risk MDS were selected, and were randomly divided into A, B and C groups according to the drug regimens: the therapeutic regimen in A group...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
低剂量地西他滨单药治疗骨髓增生异常综合征的疗效分析. 探讨低剂量地西他滨单药治疗骨髓增生异常综合征(MDS)的疗效及安全性. 选取51例中高危MDS患者,根据用药方案将他们分为A、B和C 3组:A组——地西他滨10 mg/(m<sup>2</sup>·d)×7 d,28 d为1个疗程;B组——地西他滨20 mg/(m<sup>2</sup>·d)×5 d,28 d为1个疗程;C组——地西他滨+ CAG 地西他滨10 mg/(m<sup>2</sup>·d)d 1-5,阿糖胞苷10 mg/m<sup>2</sup>皮下注射 q12h d 1-7,阿克拉霉素10 mg/d 静滴 d 1-4,重组人粒细胞刺激因子200 μg/(m<sup...
zh-cn
pair_31607315
To analyze the hematological characteristics of HbE homozygotes. Complete blood cells count and hemoglobin electrophoresis were used for phenotypic analysis of 78 cases with HbE homozygotes from Yunnan province, China. The PCR-fluorescence hybridization was used to detect the common gene mutation of thalassemia. The he...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
None
zh-cn
pair_31607316
To perform genetic analysis, prenatal diagnosis and preimplantation genetic diagnosis (PGD) in a family with a rare deletional β- thalassemia. Hematological parameters of the peripheral blood collected from all the family members were analyzed by whole blood cell analysis and capillary zone electrophoresis (CZE). Polym...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
台湾型缺失β地中海贫血的基因诊断、产前诊断和植入前遗传学诊断. 对1个罕见缺失型β地中海贫血家系进行基因诊断、产前诊断和胚胎植入前遗传学诊断及分析. 采用血常规和血红蛋白电泳分析家系中所有成员外周血的血液学指标,采用聚合酶链反应结合反向点杂交(PCR-RDB)、多重连接探针扩增技术(MLPA)及裂隙聚合酶链反应(gap-PCR)方法进行β地中海贫血基因诊断,采集脐带血或者绒毛膜组织进行产前诊断。囊胚活检滋养外胚层细胞经过全基因组扩增后利用第二代测序技术单体型构建进行胚胎植入前遗传学诊断. 基因诊断检测出该家系的先证者为罕见的台湾型缺失β地中海贫血携带者。2次产前诊断结果显示,2个胎儿均为重型β地中海贫血患者。植入前遗传学诊断发现在1...
zh-cn
pair_31607317
To investigate the gene-carrying rate and genetic types of thalassemia among the couples of child-bearing age in Ding'an, Hainan province. A total of 1742 couples at child bearing age in the region were screened for thalassemia by detecting the mean corpuscular hemoglobin (MCH) and mean corpuscular volume (MCV). If the...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
海南省定安地区婚育人群地中海贫血群筛结果分析. 了解海南省定安地区育龄夫妇地中海贫血基因携带率和基因类型分布. 收集本地区1 742对育龄夫妇,检测其外周血的平均红细胞血红蛋白含量(MCH)、平均红细胞容积(MCV),夫妇一方MCV<82 fl 和/或MCH <27 pg,对双方进行血红蛋白电泳检查。HbA2≤2.5%或HbA2>3.5%为初筛阳性,对初筛阳性夫妇进行地中海贫血基因检测. 1 742对育龄夫妇中,检出地中海贫血基因携带者478例,检出率为13.72%,夫妇携带同型地中海贫血基因的42对,占比3.67%,α-地中海贫血基因病例检出率为9.56%,β-地中海贫血基因检出率为3.10%,α-合并β-地中海贫血基因检出率为1...
zh-cn
pair_31607318
To obtain the recombinant protein of spacer domain in von Willebrand factor cleaving protease (ADAMTS13), and further study its biological function in ADAMTS13. The prokaryotic expression vector was constructed by using the template of plasmid with full-length ADAMTS13, and then transfected into E coli., following the ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Spacer区蛋白对ADAMTS13活性影响的研究. 本研究旨在获得血管性血友病因子裂解酶ADAMTS13中重组的spacer区蛋白,进一步探讨该区域对ADAMTS13功能发挥的作用. 以ADAMTS13全长质粒为模板,构建含spacer区基因序列的原核表达质粒,转染大肠杆菌, 低温(30 ℃)IPTG诱导表达,收集超声上清并鉴定。并大规模诱导表达,利用Ni-NTA琼脂糖柱,梯度咪唑淋洗法纯化蛋白,应用SDS-PAGE和Western blot法鉴定纯化产品纯度和免疫学活性。利用重组蛋白与免疫性调节的血栓性血小板减少性紫癜(iTTP)患者血浆孵育,检测血浆中ADAMTS13的活性变化. 成功构建能表达spacer区的原核表达质粒并能...
zh-cn
pair_31607319
To investigatc the curative efficacy of low dose rituximab for glucocorticoid ineffective on dependent ITP patients and its relation with sensitivity to glucocorticoid so as to provide reference basis for rational use of drugs in clinical treatmant. Seventy-ninth ITP patients enrolled in this study included the glucoco...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
利妥昔单克隆抗体治疗不同激素敏感性的ITP患者的疗效比较. 观察小剂量利妥昔单克隆抗体治疗糖皮质激素无效和依赖的ITP患者的疗效及其与激素敏感性的关系,为临床医师合理用药提供参考. 将79例ITP患者纳入研究,其中对糖皮质激素无效的19例,对糖皮质激素依赖的有60例。对所有患者给予地塞米松40 mg/d×4,d 7、14、21、28静脉滴注利妥昔单克隆抗体100 mg,治疗后对所有患者随访12个月,分析患者对激素的敏感性与利妥昔单克隆抗体治疗反应的关系。应用流式细胞术及ELISA法检测治疗前后Tregs比例,BAFF、IL-2和sCD40L水平的变化. 79例ITP患者经地塞米松联合利妥昔单克隆抗体治疗后1、3、6及12个月的总有效...
zh-cn
pair_31607321
To investigate the effects of quercetin on the apoptosis of platelets and to analyze the intrinsic mechanism. Firstly, the effects of quecetin on the apoptosis of platelets was detected by flow cytometry. Secondly, Western blot was used to detect the expression of apoptosis-related proteins in the platelets treated wit...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
槲皮素对血小板凋亡的影响及其机制. 探讨槲皮素对储存损伤期间血小板凋亡的影响及其可能的内在机制. 通过流式细胞术检测并分析经不同浓度的槲皮素处理2和4 d的血小板的凋亡情况。通过Western blot 方法检测槲皮素处理2和4 d的血小板相关凋亡蛋白表达的变化. 2、4和8 μmol/L槲皮素处理血小板d 2时的凋亡率分别为3.12%±0.32%、2.89%±0.15%、2.31%±0.28%,与对照组相比有显著性差异(P<0.01),且随着槲皮素浓度的增高,血小板的凋亡比率逐渐降低,即槲皮素对其凋亡的抑制有一定的浓度依赖性(r=-0.9985);d 4时亦观察到了类似的结果。2、4和8 μmol/L槲皮素处理2 d可促进抗凋亡蛋...
zh-cn
pair_31607322
To investigate the curative effect of simply hormone and combined gamma globulin and thrombopoietin(TPO) on primary immune thrombocytopenia(PITP). 100 patients with PITP were divided into simply drug groups, and combined drug group each for 50 cases. The patients in single drug group were given simply hormone therapy, ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
单药激素和丙种球蛋白联合TPO治疗原发免疫性血小板减少症的疗效观察. 探讨单药激素和丙种球蛋白联合血小板生成素(thrombopoietin,TPO)治疗原发免疫性血小板减少症(primary immune thrombocytopenia,PITP)的疗效. 将100例PITP患者分为单药组和联合组,各组50例。单药组采用单药激素治疗,联合组采用丙种球蛋白和TPO联合治疗。采用DAS-ELISA测定TPO、血小板激活因子(platelet activating factor,PAF)水平,比较两组临床疗效、临床指标、生化指标与药物不良反应等差异. 联合用药组治疗总有效率(90.00%)明显高于单药组(66.00%)(P<0.05)...
zh-cn
pair_31607323
To analyze and compare the correlation of platelet aggregation rate measured by platelet analyzer, platelet aggregometer and thromboelastography. The performance of platelet analyzer in platelet count and platelet aggregation function was evaluated. The platelet aggregation rate of 55 patients with type 2 diabetes mell...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
血小板分析仪、血小板聚集仪和血栓弹力图仪检测血小板聚集率. 分析并比较血小板分析仪、血小板聚集仪和血栓弹力图仪三者检测血小板聚集率的相关性. 对血小板分析仪在血小板计数和血小板聚集功能的性能方面进行评估;分别采用血栓弹力图仪、血小板聚集仪和血小板分析仪对55例2型糖尿病(T2DM)患者,单用阿司匹林(32例)、单用氯匹格雷(23例)前后血小板聚集率进行测定,并对检测结果进行比较,进一步分析不同仪器设备所测结果的相关性,将所得数据纳入统计学分析. 血小板分析仪日间和批内精密度均低于1/3总误差(7%),携带污染率为0.30%,在4.15×10<sup>9</sup>/L至1379.95×10<sup>9</sup>/L的线性范围内的回...
zh-cn
pair_31607324
To study the regulatory effect of deubiquitinase MYSM1 on differentiation of B cells to plasma cells. The interfering and overexpression plasmids of MYSM1 were constructed and then the corresponding lentiviruses were packaged. Human CD19<sup>+</sup> B cells were isolated from human peripheral blood with Miltenyi B cell...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
去泛素化酶MYSM1调控人B细胞向浆细胞的分化. 探讨去泛素化酶MYSM1对人B细胞向浆细胞分化的调控作用。. 构建去泛素化酶MYSM1的干扰载体和过表达载体,包装相应慢病毒及对照慢病毒;经人外周血磁珠分选出的CD19<sup>+</sup> B细胞;经慢病毒感染48 h后,LPS刺激诱导感染后的CD19<sup>+</sup> B细胞向浆细胞分化。流式细胞术检测CD138表达,荧光定量PCR检测B细胞及分化过程中重要转录因子的表达变化。. 干扰MYSM1表达后,B细胞向浆细胞分化比例显著升高(P<0.01),抑制浆细胞分化的转录因子Pax5和Bach2的表达水平显著下降(P<0.01),而促进浆细胞分化的转录因子Prdm1和Xbp...
zh-cn
pair_31607325
To investigate the effects of cytomegalovirus (CMV) DNA load on immune reconstitution and clinical outcomes of patients after unrelated cord blood transplantation (UCBT). Eight-color flow cytometry was used to dynamically monitor the changes of peripheral blood lymphocyte subsets of 41 patients at one year after UCBT, ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
单份非血缘脐血移植术后巨细胞病毒的DNA负荷对免疫重建及移植结局的影响. 探索巨细胞病毒(CMV)的DNA负荷对非血缘脐血移植(UCBT)后免疫重建和临床结局的影响。. 8色流式细胞术动态监测41例患者UCBT后1年的外周血淋巴细胞亚群变化,同时纳入10例健康体检者作为正常人对照。根据CMV的DNA负荷水平(DNA拷贝<1 000/ml和DNA拷贝≥1 000/ml)将患者分为2组,比较分析移植后CMV的DNA负荷对淋巴细胞亚群重建及移植结局的影响. CMV的DNA高负荷组呈现较快的T细胞重建,且移植后1年内的T细胞数均高于DNA低负荷组,2组间T细胞数在移植后1和9个月分别为0.38×10<sup>9</sup> /L vs 0....
zh-cn
pair_31607326
To explore the causes and specific conditions of blood donation reaction under the collective emergency unpaid blood donation, and to provide theoretical basis and decision-making reference for drafting the collective emergency unpaid blood donation and blood donation safety. Through a combination of prospective and re...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
集体应急无偿献血条件下献血反应原因及情况分析. 探讨集体应急无偿献血条件下献血反应原因及其具体情况,为进一步组织好集体应急无偿献血与献血安全提供理论依据和决策参考。. 通过前瞻性和回顾性相结合模式,利用统计学方法对比研究分析2016年1月至2018年8月10 401人次参加集体应急无偿献血发生献血反应的原因及其情况。. 10 401人次全部以坐式方式献血,共发生献血反应293例。通过献血服务的逐年完善,2017年与2018年中度献血反应均比2016年明显减少(P<0.05); ≤100、200、300和400 ml 等4组实际献血量群体,其献血反应发生率差异有统计学意义(P<0.05);1、2、3与>3次献血者献血反应发生率差异也有...
zh-cn
pair_31607327
To identify the blood group of a patient with DEL phenotype combined with positive direct anti-human globulin test and to analyze the pedigree. Routine serological reagents were used for serological analysis of RhD blood group in the pedigree members. Exons and flanking sequences of RHD gene were amplified, sequenced a...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
DAT阳性的DEL血型鉴定及其家系分析. 对1例DEL血型合并直接抗人球蛋白试验阳性患者进行血型鉴定并分析其遗传规律。. 采用常规血清学试剂对先证者及其家系成员RhD血型进行血清学分析,使用PCR-SSP方法对RHD基因10个外显子及侧翼序列进行扩增、测序并分析其杂合性。对先证者家系进行调查并分析DEL血型遗传规律。. 先证者DAT强阳性,RHD基因9外显子存在1227G>A等位基因(RHD*DEL1),其母亲为RHD*DEL1携带者。RHD合子型鉴定为 RHD+/RHD-,提示该个体单倍型为CD<sup>1227A</sup>e/ Cde。. 先证者为DEL型(RHD*DEL1)。.
zh-cn
pair_31607328
To compare the effects of intravenous and subcutaneous injection of bortezomib on incidence and relative risk of peripheral neuropathy in patients with multiple myeloma(MM). The electronic database of PubMed, Embase, Cochrance library, CNKI and related meeting records were searched by computers. The data were derived a...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
硼替佐米不同给药途径对周围神经病变的发生率和风险的影响. 比较硼替佐米静脉和皮下注射的不同给药途径对病人周围神经病变发病率及其相对风险的影响. 计算机搜索了PubMed、Embase、Cochrance library、CNKI(中国知网)电子数据库及相关会议记录。数据全部来自随机对照研究(randomized controlled study,RCT)。根据统计学方法计算静脉和皮下注射给药致周围神经病变的发生率、相对危险度(relative risk,RR)和95%的置信区间. 选择4篇RCT研究荟萃分析表明,注射病人总共911例(皮下和静脉组分别为479例和432例)。周围神经病变在静脉注射组的发生率为41.4%(95%CI=0...
zh-cn
pair_31607329
To detect the expression of serum HMGB1 and CD14<sup>+</sup> monocyte Toll-like receptors in children with hemophagocytic syndrome (HPS), and to analyze its effect on the prognosis of children. Eight-three children with HPS admitted in Department of pediatrics of Wuhan Children's Hospital Affiliated to Tongji Medical C...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
噬血细胞综合征儿童血清HMGB1、CD14<sup>+</sup>单核细胞Toll样受体的表达及对预后的影响. 检测噬血细胞综合征(hemophagocytic syndrom,HPS)患儿血清HMGB1、CD14<sup>+</sup>单核细胞Toll样受体的表达水平,并分析它们对噬血细胞综合征患儿预后的影响。. 选取华中科技大学同济医学院附属武汉儿童医院儿科收治的83例噬血细胞综合征患儿纳入HPS组,50例同龄体检健康儿童纳入观察组,采集外周血,采用流式细胞术检测外周血CD14<sup>+</sup>单核细胞Toll样受体(TLR2、TLR4、TLR6)水平,酶联免疫吸附测定法检测血清中HMGB1表达水平,并分析TLR2、TLR...
zh-cn
pair_31607330
To investigate the clinical characteristics, prevention and treatment of invasive fungal disease (IFD). The clinical data of 164 patients who met the diagnostic criteria of IFD in our center from January 2012 to January 2015 were retrospectively analyzed. The incidence, clinical characteristics, related factors, treatm...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
儿童血液病合并侵袭性真菌病164例临床分析. 探讨儿童侵袭性真菌病(invasive fungal disease,IFD)的临床特点和防治方法。. 回顾性分析本中心2012年1月至2015年1月符合IFD诊断标准的164例临床资料,了解其发病率、临床特征、相关因素,治疗方法和预后。. 在本院收治的1 289例血液病患儿中164例发生IFD,发病率为12.7%;感染部位主要为单纯肺部、血液和胃肠道,发生率分别为84.2%、5.5%和3%;共检出真菌35例,其中白色假丝酵母菌、曲霉菌和光滑假丝酵母菌检出率较高,分别为51.5%、20%和14.3%;164例患儿完全缓解36例,部分缓解97例,疾病稳定10例,进展11例,死亡10例,总有...
zh-cn
pair_31607331
To analyze the diagnostic value of (1, 3) -β-D-glucan and galactomannan (GM) tests in the patients with acute leukemia complicated by invasive fungal disease, and explore the application of serological detection (G/GM) and lung CT for early diagnosis of invasive fungal disease (IFD). A total of 493 patients with acute ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
G及GM试验在急性白血病合并侵袭性真菌病中的诊断价值. 分析G及GM试验在急性白血病患者合并侵袭性真菌病中的诊断效能,及其与CT在侵袭性真菌病早期诊断中的应用。. 本院血液科2016年下半年急性白血病患者怀疑侵袭性真菌病(IFD)行G及GM试验检测的病人共493例。根据IFD的诊断标准,将患者分为:IFD确定组(包括确诊及临床诊断IFD,62例),IFD未确定组(包括拟诊及非IFD,431例)。分析2组患者G及GM试验结果,并评价二者单独及联合诊断的诊断效能。此外,从病例中筛选入院时肺部CT结果阴性,在住院过程中CT显示肺部有改变及血清学检测结果显示阳性的患者26例,比较血清学检测阳性结果与CT显示肺部改变的时间差异。. G试验在I...
zh-cn
pair_31607332
To knockout ADRB2 gene rapidly and efficiently in human primary T cells by using CRISPR/Cas9 technology and multiple sgRNAs strategy. Six paired-sgRNAs, which were designed to target the 5' constitutive coding exons of ADRB2 gene, were cloned into pGL3-U6-sgRNA-PGK-Puro vector separately. The expre-ssion vectors contai...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
基于CRISPR/Cas9技术构建多重sgRNA实现在人原代T细胞中敲除ADRB2基因. 利用CRISPR/Cas9技术,通过多重sgRNA策略,实现在人原代T细胞中ADRB2基因的快速、高效敲除. 针对ADRB2基因5′端组成性外显子设计6条sgRNA,通过与pGL3-U6-sgRNA-PGK-Puro载体连接,构建6个单一sgRNA表达载体,分别与Cas9表达载体瞬时转染HEK-293T细胞;通过T7EN I酶切检测其介导的切割效率,筛选出4条高活性的配对sgRNA。继而将4条sgRNA有序串联克隆至pGL3-U6-sgRNA-ccdB-EF1α-Puro载体,构建成靶向ADRB2基因的多重sgRNA表达载体。瞬时转染HEK-2...
zh-cn
pair_31607334
Abstract  The promyelocytic leukemia (PML) gene encoded PML protein as a tumor suppressor protein, plays important roles in the occurrence and development of various cancers including acute promyelocytic leukemia. Recent studies have indicated that there are a variety of post-translational modifications of the PML prot...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
PML蛋白翻译后修饰参与PML核体功能调节的研究进展. 早幼粒细胞白血病基因(promyelocytic leukemia, PML)编码的PML蛋白,作为抑癌因子在急性早幼粒细胞白血病以及多种癌症的发生及发展中扮演着重要的角色。PML蛋白在细胞中可发生多种形式的翻译后修饰,如SUMO化(SUMOylation)、泛素化(ubiquitination)、磷酸化(phosphorylation)和乙酰化(acetylation)修饰等。PML蛋白的这些修饰可直接影响PML核体(PML nuclear bodies,PML-NBs)的形成、DNA损伤修复、细胞凋亡等功能。异常修饰不仅可以引起血液系统肿瘤的发生,同时与肿瘤耐药有着密切关系...
zh-cn
pair_31607335
Abstract  B cell maturation antigen (BCMA) is an ideal target for precise treatment due to its highly selective expression on malignant myeloma cells. This review summarizes briefly the advances in the latest research progress on biological activity of BCMA, its significance as a biomarker and immunotherapy direcited a...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
B细胞成熟抗原(BCMA)靶向免疫治疗多发性骨髓瘤的研究进展.  B细胞成熟抗原(B cell maturation antigen,BCMA)因其在恶性骨髓瘤细胞上高度选择性表达,故是理想的精准治疗靶点。本文就BCMA的生物学活性、作为生物标志物的意义以及针对抗B细胞成熟抗原开发的免疫疗法(双特异性抗体,抗体药物偶联物,嵌合抗原受体T细胞疗法)的最新研究进展作一综述。.
zh-cn
pair_31607336
Abstract Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by less than 100×10<sup>9</sup>/L platelet count in peripheral blood. The pathogenesis of ITP is complex and has not been fully elucidated. Currently, researches on the pathogenesis of ITP mainly focus on the disorders of humoral immun...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
原发性免疫性血小板减少症的发病机制研究进展. 原发性免疫性血小板减少症(Immune thrombocytopenia,ITP)是一种复杂的自身免疫疾病,以外周血中血小板计数<100×10<sup>9</sup>/L为特点。ITP的发病机制复杂,尚未完全阐明,目前对ITP发病的研究主要针对于体液免疫失调以及细胞免疫失调等方面。近年来,研究该发病机制取得了一些新的进展,包括非依赖Fc γ R 介导的血小板清除途径,可以调节T、B细胞的金属蛋白酶(ADAM)10,遗传因素中的微小RNA的表达异常等。在多种因素的共同作用下,机体免疫系统的失衡,导致ITP的发生。本文就近年来针对ITP研究的体液免疫,细胞免疫以及其他可能的新发病机制研究进展...
zh-cn
pair_31608529
Many dermatological topicals are available for human use and may be toxic to dogs and cats. No epidemiological studies have been performed in the US population on the use of dermatological topical prescription drugs, and their toxicosis to dogs and cats. Summarize the variety of dermatological topical prescriptions pot...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
背景: 许多人皮肤外用药可能对犬和猫有毒。在美国,尚无使用人皮肤外用处方药的犬和猫数量,及其中毒情况的流行病学调查。 目的: 统计美国宠主可能使用的各种皮肤外用处方药,并报告犬和猫的接触数量和中毒的流行病学。 动物/受访者: 数据来自美国国家健康和营养检查调查(NHANES),311,065,381名美国居民中的10,170名作为代表。美国防止虐待动物协会(ASPCA)动物毒物控制中心(APCC)数据库记录共有61,169例犬和猫接触过人皮肤外用药。 方法和材料: 分析2011年-2014年从NHANES调查受访者的处方药数据。搜索2001年1月至2018年1月期间,APCC数据库中皮肤外用处方药病例的记录。 结果: 1.33±0....
zh-cn
pair_31608529
Many dermatological topicals are available for human use and may be toxic to dogs and cats. No epidemiological studies have been performed in the US population on the use of dermatological topical prescription drugs, and their toxicosis to dogs and cats. Summarize the variety of dermatological topical prescriptions pot...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
De nombreux topiques dermatologiques sont disponibles chez l'homme et pourraient être toxiques chez le chien et le chat. Aucune étude épidémiologique n'a été réalisée aux US sur l'utilisation des traitements topiques dermatologiques sur prescription et leur toxicité chez le chien et le chat. Résumer la variété des pres...
fr
pair_31608529
Many dermatological topicals are available for human use and may be toxic to dogs and cats. No epidemiological studies have been performed in the US population on the use of dermatological topical prescription drugs, and their toxicosis to dogs and cats. Summarize the variety of dermatological topical prescriptions pot...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Im Humanbereich stehen viele dermatologische Produkte zur äußerlichen Anwendung zur Verfügung, die für Hunde und Katzen toxisch sein könnten. Es sind bisher keine epidemiologischen Studien in der US Population über die Anwendung dermatologischer äußerlich anzuwendender verschreibungspflichtiger Medikamente und ihrer Gi...
de
pair_31608529
Many dermatological topicals are available for human use and may be toxic to dogs and cats. No epidemiological studies have been performed in the US population on the use of dermatological topical prescription drugs, and their toxicosis to dogs and cats. Summarize the variety of dermatological topical prescriptions pot...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Muitos produtos tópicos estão disponíveis para humanos e podem ser tóxicos para cães e gatos. Não há estudos epidemiológicos realizados com a população dos EUA sobre o uso de produtos dermatológicos tópicos e a sua toxicidade para cães e gatos. Sintetizar uma variedade de produtos dermatológicos tópicos potencialmente ...
pt
pair_31608529
Many dermatological topicals are available for human use and may be toxic to dogs and cats. No epidemiological studies have been performed in the US population on the use of dermatological topical prescription drugs, and their toxicosis to dogs and cats. Summarize the variety of dermatological topical prescriptions pot...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
ANTECEDENTES: hay muchos agentes tópicos dermatológicos disponibles para uso humano que pueden ser tóxicos para perros y gatos. No se han realizado estudios epidemiológicos en la población de USA acerca del uso de medicamentos tópicos dermatológicos recetados y su toxicosis en perros y gatos. OBJETIVOS: resumir la vari...
es
pair_31612489
To explore and understand the views of clients and formal and informal caregivers about the experienced quality of home care for older people. A descriptive qualitative study was conducted using individual interviews. Six home care clients, four formal and six informal caregivers were recruited from two Dutch home care...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的: 探讨和了解客户和正式和非正式护理人员对老年人体验居家护理的质量的看法。 设计: 采用个体访谈进行描述性定性研究。 方法: 从荷兰两家家庭护理机构招募了6名家庭护理接受客户、4名正式护理人员和6名非正式护理人员。在2018年4月至11月期间对每个人进行了个人半结构化访谈。长期护理框架的个人体验质量被用来指导数据收集和内容分析。 结果: 分析揭示了影响居家护理质量的几个重要因素,如首选看护者数量较少、有充足的看护时间、有利于开放交流和幽默的关怀氛围。参与者还表示护理程序符合接受照顾人以前的生活方式很重要。一种更“亲密”的富有信任、率真和同情心的个人护理关系比“分离”式的专业护理关系更好。 结论: 本研究从病人和家庭护理中正式和非...
zh-cn
pair_31612517
To test the direct effects of different surface acting strategies and the interactive effects of surface acting and recovery experiences on nurses' well-being. A two-wave study design. Chinese hospital nurses (N = 372; 47.3% of initial sample) reported on their levels of surface acting, recovery experiences and well-be...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的: 此研究旨在检测不同表面行为策略的直接影响,以及表面行为与康复经验对护士幸福感的交互作用。 设计: 一项两波研究设计。 方法: 我们在2017年11月和2018年11月通过纸笔调查了解中国医院护士(N = 372;初始样本的47.3%)的表面行为水平、康复经验以及幸福感。 发现: 表面行为会对护士的幸福感产生长期影响。与正面表达相比,负面压抑一般会产生更多的负面影响。康复经验在表面行为和护士的幸福感中起到缓解作用。 结论: 这些发现为表面行为的长期影响提供了初步证据,并展现了医院护士如何通过培养康复经验从而避免表面行为所产生的不良影响。 影响: 表面行为是长期压力源,会对护士的幸福感产生长期影响。与积极表达相反,负面压抑更会产...
zh-cn
pair_31612518
This research protocol addresses the development of web-based modules for the 'creating opportunities for personal empowerment: symptom and technology management resources' intervention with caregivers of children who require medical technology. The commonly experienced symptoms of fever and increased respiratory sympt...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
目的: 本研究方案针对“给人权创造机会:病症及技术管理资源”干预需要医疗技术的儿童看护者的网络模块的开发。常见的发热症状和呼吸系统症状加重(咳嗽、喘息、分泌物增多),以及技术护理(气管造口术、呼吸设备和喂食管)都在护士主导和制定的干预措施中得到了解决。 设计: 本研究的目的在于开发基于网络的干预模块,并通过系统、结构化的流程和形式通过专家和护理审查人员的审查。 方法: 干预措施包括基于证据、基于理论的模块,这些模块通过使用基于网络的格式管理儿童的病症和技术来解决儿童最常见的情绪和行为反应。为了保证干预措施的真实性,专家和护理审查人员(例如患有多种复杂慢性疾病的儿童的护理人员和技术)将审查模块,然后在可行性测试之前对其进行完善。该研究...
zh-cn
pair_31613412
To report and compare pregnancy outcome in dichorionic (DC), monochorionic diamniotic (MCDA) and monochorionic monoamniotic (MCMA) twin pregnancies with two live fetuses at 11-13 weeks' gestation and to examine the impact of endoscopic laser surgery for severe twin-twin transfusion syndrome (TTTS) and/or selective feta...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
妊娠11-13周有两个活胎的双胎妊娠的结局 目的: 报告和比较妊娠11-13周有两个活胎的双胎(DC)、单绒毛膜双胎(MCDA)和单绒毛膜单胎(MCMA)的双胎妊娠的妊娠结局,并检查内镜激光手术治疗严重双胎输血综合征(TTTS)和/或选择性胎儿生长受限(sFGR)对MCDA双胎结局的影响。 方法: 这是对2002年至2019年间在妊娠11-13周接受常规超声检查的双胎妊娠前瞻性收集数据的回顾性分析。在没有重大异常的妊娠中,我们比较了DC、MCDA和MCMA双胞胎的总体存活率、妊娠< 24周时的胎儿丢失率、妊娠>24周时的围产儿死亡率、妊娠< 37周和< 32周时的分娩率以及出生体重<第五百分位数。 结果: 6225名双胎妊娠的研究人...
zh-cn
pair_31613412
To report and compare pregnancy outcome in dichorionic (DC), monochorionic diamniotic (MCDA) and monochorionic monoamniotic (MCMA) twin pregnancies with two live fetuses at 11-13 weeks' gestation and to examine the impact of endoscopic laser surgery for severe twin-twin transfusion syndrome (TTTS) and/or selective feta...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Resultado del embarazo de gemelos con dos fetos vivos a las 11-13 semanas de gestación OBJETIVOS: Informar y comparar el resultado de embarazos de gemelos dicoriales (DC), monocoriales diamnióticos (MCDA) y monocoriales monoamnióticos (MCMA) con dos fetos vivos a las 11-13 semanas de gestación y examinar la repercusión...
es
pair_31617203
Behavioral health and substance use centers have started focusing efforts on creating, adopting, and implementing evidence-based practices and programs that effectively address the needs of women and, particularly, mothers entering treatment with children. However, women with substance use disorders (SUDs) remain an un...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
行为健康和物质使用中心开始把努力的重心放在创造、采用、实施循证措施和相关项目,以期有效地针对女性的需要,特别是那些带孩子一起开始接受治疗的母亲们的需要。但是,药物滥用失常(SUDs)的女性仍然是较少被关注和较少被研究的人群,更不用说关注和研究那些有孩子要抚养的女性,她们对于治疗药物滥用失常症状的特殊治疗需要及其复杂性。家庭治疗师的系统性训练是一个受到重视的方法,它有助于增进对针对药物滥用失常(SUDs)的母亲们及其家庭的治疗的理解和治疗的具体实施。这项研究使用超验的现象学研究方法,探索了在家庭为中心的物质使用治疗期间的母亲们如何抚育孩子。数据分析归纳出和母亲,养育孩子,给母亲和孩子的支持相关方面的主题。有两个明显的主题浮现出来: (...
zh-cn
pair_31617203
Behavioral health and substance use centers have started focusing efforts on creating, adopting, and implementing evidence-based practices and programs that effectively address the needs of women and, particularly, mothers entering treatment with children. However, women with substance use disorders (SUDs) remain an un...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Los centros para la salud conductual y el consumo de sustancias han comenzado a centrar sus esfuerzos en la creación, la adopción y la implementación de prácticas y programas factuales que aborden eficazmente las necesidades de las mujeres y, particularmente, de las madres que ingresan en un tratamiento con hijos. Sin ...
es
pair_31617265
Food allergy is a possible cause of atopic dermatitis (AD) in dogs; it is typically diagnosed following an eight-week elimination diet trial (EDT) and a provocation with the original diet. This lengthy procedure is difficult for owners and its interpretation may be unclear. To test the effect of prednisolone used in th...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
背景: 食物过敏可能是犬异位性皮炎(AD)的原因;通常需要8周食物排查试验(EDT),并随后用原来的日粮激发才能确诊。对于宠主而言,过程冗长难以坚持,对结果的判读也不明确。 假设/目的: 开始EDT的前几周使用泼尼松龙,检测是否能缩短诊断时间。旨在传统推荐的八周之前完成食物激发。 动物: 53只AD患犬入选本研究项目。 方法和材料: 所有犬均饲喂市售的、蛋白质充分水解的宠物商业粮,同时用泼尼松龙治疗至少两周,以控制瘙痒和炎症。泼尼松龙两周后停药,只要未发生急性症状,就对犬进行食物激发。给有复发症状的犬饲喂水解粮至少八周,继续或停止泼尼松龙治疗。 结果: 泼尼松龙两周停用后,53只犬有10只(19%)没有复发:他们用原来食物激发后症状...
zh-cn
pair_31617265
Food allergy is a possible cause of atopic dermatitis (AD) in dogs; it is typically diagnosed following an eight-week elimination diet trial (EDT) and a provocation with the original diet. This lengthy procedure is difficult for owners and its interpretation may be unclear. To test the effect of prednisolone used in th...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
L'allergie alimentaire est une cause possible de dermatite atopique (AD) chez le chien; elle est usuellement diagnostiquée à la suite d'un régime d’éviction de huit semaines (EDT) et une provocation avec l'aliment initial. Cette procédure longue est difficile pour les propriétaires et son interprétation peut être doute...
fr
pair_31617265
Food allergy is a possible cause of atopic dermatitis (AD) in dogs; it is typically diagnosed following an eight-week elimination diet trial (EDT) and a provocation with the original diet. This lengthy procedure is difficult for owners and its interpretation may be unclear. To test the effect of prednisolone used in th...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
Eine Futtermittelallergie ist eine mögliche Ursache für die atopische Dermatitis (AD) bei Hunden; sie wird üblicherweise nach einer acht-wöchigen Eliminationsdiät (EDT) und einer Provokation mit dem ursprünglichen Futter diagnostiziert. Diese langwierige Prozedur ist für die BesitzerInnen schwierig und die Interpretati...
de
pair_31617265
Food allergy is a possible cause of atopic dermatitis (AD) in dogs; it is typically diagnosed following an eight-week elimination diet trial (EDT) and a provocation with the original diet. This lengthy procedure is difficult for owners and its interpretation may be unclear. To test the effect of prednisolone used in th...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
A alergia alimentar é uma causa possível de dermatite atópica (DA) em cães e é mais comumente diagnosticada após oito semanas de dieta de eliminação (DE) e desafio com a dieta original. Este longo processo é difícil para os proprietários e sua interpretação pode ser confusa. HIPÓTESE/OBJETIVOS: Testar o efeito da predn...
pt
pair_31617265
Food allergy is a possible cause of atopic dermatitis (AD) in dogs; it is typically diagnosed following an eight-week elimination diet trial (EDT) and a provocation with the original diet. This lengthy procedure is difficult for owners and its interpretation may be unclear. To test the effect of prednisolone used in th...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
la alergia alimentaria es una posible causa de dermatitis atópica (AD) en perros; por lo general, se diagnostica después de una prueba con dieta de eliminación de ocho semanas (EDT) y una provocación con la dieta original. Este largo procedimiento es difícil para los propietarios y su interpretación puede ser poco clar...
es
pair_31621212
Ecosystem services (ESs) are the research highlight and hot topic in ecology, geography and environmental economics. Based on the literature database on ecosystem services from Web of Science, Citespace, Carrot 2 and textual analysis were used to review the progresses of ESs research during 1997-2018. The results showe...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
生态系统服务研究已成为生态学、地理学、环境经济学等学科的热点议题.基于Citespace与Carrot 2文献分析工具,以Web of Science为数据源,本文分析了1997—2018年生态系统服务研究热点与发展趋势.结果表明: 近20年来,生态系统服务研究文献数量、研究机构均明显增加,主要的发文国家有美国、英国、德国、中国、澳大利亚,其中,美国的发文量与影响力最大.综合来看,中国在生态系统服务研究方面起步较晚,近期发展势头迅猛,科研产出量显著增加;但与国际相比还存在一定差距,文献质量及影响力还有待提高,国际合作交流有待提升.生态系统服务的热点主要集中在评估方法与模型、气候变化、生物多样性、土地利用变化、权衡与协同关系、科学研究...
zh-cn
pair_31621213
Grazing is one of the most important practices for humans to manage grassland ecosystems. The disturbances of feeding, trampling, resting and excreta returning by herbivores will change plant communities and soil nutrient cycling. With the intensification of human activities, the intensity and frequency of grazing were...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
放牧是人类管理利用草地生态系统的最主要途径之一.食草动物的采食、践踏、卧息和排泄物归还等干扰不仅会改变草地地上植物群落,也会对土壤养分循环产生显著的影响.随着人类活动的加剧,放牧强度和频率也在逐渐增加,从而对草地土壤氮素循环关键过程产生重要影响.放牧主要通过改变土壤的物理性质、土壤氮库以及微生物的组成和结构,进而影响氮素在土壤中的迁移与转化.适度放牧会促进土壤氮素的矿化过程和硝化过程,加快氮素的周转,有利于植物吸收可利用氮素,而对于反硝化的影响与草地的水热条件和土壤类型等密切相关.目前,关于放牧强度对土壤氮素循环关键过程影响的研究结果不一致,其影响机制尚不明晰,尤其对于不同类型的草原仍存在较大的差异.本研究在大量查阅国内外已有研究结...
zh-cn
pair_31621214
Soil acidification due to exogenous nitrogen (N) deposition has been received sufficient attention in the past several decades. Whether the N-induced soil acidification is modulated by the altering precipitation regimes remains unclear. In this study, based on a five-year (2013-2017) manipulative field experiment with ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
氮(N)沉降增加带来的土壤酸化问题已经得到广泛的关注,然而土壤酸化是否受到未来降水格局改变的影响研究相对匮乏.本研究基于内蒙古温带典型草原5年(2013—2017年)的N添加(10和40 g N·m<sup>-2</sup>·a<sup>-1</sup>)和增雨(增雨量80 mm,分2 mm×40次、5 mm×16次、10 mm×8次、20 mm×4次、40 mm×2次5种处理)控制试验分析了水分对N添加后土壤酸化的影响.结果表明: 40 g N·m<sup>-2</sup>·a<sup>-1</sup> N添加在土壤酸化出现的时间、酸化程度以及酸化随时间的变化速率上均大于10 g N·m<sup>-2</sup>·a<sup>-1...
zh-cn
pair_31621217
We examined the spatial distribution of Tenebrionidae in Alxa Plateau and its environmental response based on the investigation of Tenebrionidae in Alxa Plateau, combined with the temperature, precipitation and solar radiation data, using Grid-Cluster analysis, OriginPro 9.0 and Canoco 5.0 analysis software. The result...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为探究拟步甲在阿拉善高原的空间分布及其环境响应,在对阿拉善高原拟步甲分布调查的基础上,结合温度、降雨及太阳辐射数据,利用栅格分析法并采用OriginPro 9.0、Canoco 5.0等软件,对阿拉善高原拟步甲的空间分布格局及其与气象因子的关系进行研究.结果表明: 由南至北随纬度增加,阿拉善高原拟步甲物种的数量逐渐上升,至峰值后逐渐下降,拟合曲线呈抛物线型.由西至东随经度增加,阿拉善高原拟步甲物种数量逐渐上升,至峰值后逐渐下降,拟合曲线呈近似单峰型.随海拔上升,阿拉善高原拟步甲的物种数量逐渐上升,至峰值后逐渐下降,拟合曲线呈单峰型.降雨量、温度、太阳辐射对阿拉善高原拟步甲物种数量的纬向分布影响显著.随降雨量增加,物种数呈单峰型变化,...
zh-cn
pair_31621218
Carbon isotope in tree ring is an effective indicator of climate and environmental change. However, few studies have analyzed the indication effect of tree ring carbon isotope on net primary productivity (NPP) of forests. Based on meteorological factors of growing seasons, we analyzed the variation trend and the relati...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
解析树木年轮碳同位素变化是揭示气候与环境变化的有效途径,然而少有研究分析年轮碳同位素对森林净初级生产力(NPP)的指示效应.基于生长季气象因子,分析了长白山红松年轮δ<sup>13</sup>C记录序列与阔叶红松林红松种群NPP变化趋势以及两者之间的相关关系.结果表明: 1970年以前,研究区红松年轮δ<sup>13</sup>C与红松种群NPP变化同步,且两者间呈极显著线性正相关关系,年轮δ<sup>13</sup>C记录了气候变化对红松种群NPP的影响;1970年以后,红松年轮δ<sup>13</sup>C与红松种群NPP变化出现分异,两者呈负相关关系但相关性不显著,表明干旱等其他环境因子的影响使年轮δ<sup>13</sup>...
zh-cn
pair_31621219
Carbon fluxes in a Haloxylon ammodendron plantation in the oasis-desert ecotone of Minqin was measured using an eddy covariance system. To provide scientific data for carbon source/sink assessment, we quantitatively analyzed the characteristics of CO<sub>2</sub> flux and its driving factors in the growing season from M...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
基于涡动相关系统观测的民勤绿洲荒漠过渡带梭梭人工林生态系统通量资料,定量分析了2018年生长季(5—10月)碳通量变化特征及其影响因子,为民勤梭梭人工林生态系统碳源/汇的评估提供基础数据.结果表明: 生长季净碳交换量在日尺度上呈对称的“U”型曲线变化;在季节尺度上,呈双峰曲线变化规律,各月均为碳汇,总固碳量为34.38 g C·m<sup>-2</sup>,且9月固碳量较高,为12.31 g C·m<sup>-2</sup>,7月最低,为0.89 g C·m<sup>-2</sup>.白天生态系统净碳交换随光合有效辐射的增加而增加,符合直角双曲线关系,但当饱和水汽压差大于2.5 kPa时,增加程度减弱.生态系统呼吸与气温呈较好的指数...
zh-cn
pair_31621222
Studying the effects of rainfall change on morphological characteristics, spatial pattern and spatial correlation of desert dominant plants could help to predict the response of desert ecosystem to global climate change. We conducted a 10-year simulated rainfall addition experiment and examined the morphological charac...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
研究降雨变化对荒漠优势植物形态特征、空间点格局及空间关联性的影响有助于预测荒漠生态系统对全球气候变化的响应.以乌兰布和沙漠典型荒漠植物唐古特白刺和油蒿为研究对象,进行了连续10年的模拟增雨试验,运用Programita软件,采用Ripley <i>K</i>函数和Monte Carlo随机模拟方法,对长期模拟增雨条件下两种植物形态特征、空间格局及空间关联性进行研究.结果表明: 不同增雨处理下唐古特白刺和油蒿植株的数量、高度、平均冠幅和基径均存在显著差异,增雨处理的唐古特白刺和油蒿植株数量、高度、平均冠幅和基径均显著大于对照,并随着增雨量的增大而增大.当增雨量小于72 mm时,白刺枝条具有明显的聚集分布趋势;当增雨量大于72 mm后,...
zh-cn
pair_31621223
We examined the effects of different salt stress intensities (control, mild, moderate, severe) on the growth traits, photosynthetic and fluorescence characteristics, and root architecture of three Corylus heterophylla × C. avellan varieties (Xinzhen 1, Xinzhen 2, Xinzhen 3). The results showed that the new shoot length...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
以平欧杂种榛3个品种(新榛1号、新榛2号、新榛3号)幼苗为材料,研究不同盐胁迫程度(对照、轻度、中度、重度)对幼苗生长性状、光合荧光特性以及根系构型的影响.结果表明: 3个品种幼苗的新稍长度、基径、叶面积,以及根、茎、叶、总生物量随着盐胁迫的增强而降低,根冠比则增加.中度、重度盐胁迫下3个品种幼苗的净光合速率较对照分别显著降低20.5%和43.2%.轻度、中度、重度盐胁迫下的蒸腾速率和气孔导度较对照分别降低2.0%、16.3%、32.0%和10.2%、35.7%、60.1%.随着盐胁迫的增强,胞间CO<sub>2</sub>浓度缓慢上升,水分利用效率呈先上升后下降的趋势,并在轻度盐胁迫下达到最大值.3个品种幼苗的初始荧光随着盐胁迫的...
zh-cn
pair_31621224
To promote the application of domestic high-resolution satellite data in large-scale carbon storage estimation and measurement, a total of 206 high-resolution remote sensing images covering Hunan Province were used as the data source, and the estimated minimum unit was fixed as a 0.06 hm<sup>2</sup> square composed of ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为推广国产高分数据在大尺度范围碳储量估测计量的应用,采用覆盖湖南省的206景高分辨率遥感影像,将估测的最小单元固定为由多个像元组合成的面积为0.06 hm<sup>2</sup>的正方格,通过解译标志的建立和提纯,在森林信息提取上,利用基于像元法和面向对象分类法进行比较;在乔木林碳储量估测上,利用稳健估计、偏最小二乘法和基准样地法(<i>k</i>-NN)估计进行比较,最后实现了对湖南省森林的碳储量估测,并生成了全省的碳密度等级分布图.结果表明: 基于样地自动提取的解译标志在经过提纯后,能进一步增加乔木林提取精度;对于大尺度范围森林植被碳储量估测,无论是在森林信息提取还是乔木林碳储量建模方面,<i>k</i>-NN算法都体现了较大优...
zh-cn
pair_31621228
In this study, data of 19 climatic factors were downloaded from the World Climate website. A total of 233 Cymbidium kanran distribution data were obtained through online review and field visits. Using MaxEnt model and combined with ArcGIS spatial analysis technology, the potential distribution area and distribution pat...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
通过实地调查及网上查阅得到寒兰分布数据共233个,并从世界气候网站下载19个气候因子数据,利用MaxEnt模型模拟寒兰潜在分布区,结合ArcGIS空间分析技术,模拟了寒兰不同时期分布格局,推测寒兰末次冰期和2070年分布格局.结果表明: 模型训练集的曲线下面积(AUC值)为0.957,验证集AUC值为0.953,模型预测的准确性较高.寒兰当前分布主要受最干季度降水量、年均降水量、最湿季度降水量和年均温度范围影响,其贡献率分别是50.3%、15.9%、8.4%、4.4%,总贡献率达79%.在末次冰期时代,寒兰分布区主要是武夷山、罗霄山、南岭、台湾五大山脉以及广西省北部一些丘陵.从当前到2070年,寒兰分布区域整体将缩小22.4%,其中...
zh-cn
pair_31621231
To tackle the issue of rainfall delay during dryland wheat sowing season and further examine the effects of seeding rate on water use and yield formation, a field experiment was conducted at Wenxi Experimental Station, Shanxi Province between 2015 and 2017. We used two sowing dates, i.e. September 20 and October 10 as ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为解决旱地小麦等雨播种的生产现状,明确播量对土壤水分利用和产量形成的调控机制,于2015—2017年在山西闻喜试验基地开展大田试验,以早播(9月20日,EB)、晚播(10月10日,LB)两个播期为主区,以低密度(67.5 kg·hm<sup>-2</sup>,LD)、中密度 (90 kg·hm<sup>-2</sup>,MD)、高密度(112.5 kg·hm<sup>-2</sup>,HD)3个播量为副区,研究播期播量对旱地小麦土壤水分消耗和植株氮素运转的影响.结果表明: 早播较晚播生育期土壤总耗水量增加11~22 mm;随播种密度的增加,生育期土壤总耗水量增加2~20 mm,且早播条件下,花前土壤耗水量增加,晚播条件下,花后土壤耗...
zh-cn
pair_31621233
A total of six treatments, including continuous conventional tillage (CT), rotary tillage (RT), subsoiling (ST), no-tillage (NT), conventional-no tillage (CT-NT) and subsoiling-no tillage (ST-NT), were conducted to examine the effects of different tillage types on soil aggregates distribution and stability of irrigated...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
2014—2017年在连续翻耕8年的玉米地上设置连续翻耕(CT)、旋耕(RT)、深松(ST)、免耕(NT)和翻耕-免耕(CT-NT)、深松-免耕(ST-NT)6个耕作处理,研究不同耕作方式对甘肃引黄灌区灌耕灰钙土团聚体分布及稳定性的影响.结果表明: NT和ST-NT处理促进了0~40 cm土层大团聚体形成,并提高了其稳定性;CT和RT处理由于对土壤的强烈扰动,耕层土壤团聚体大小分布和稳定性都显著降低.机械稳定性团聚体以NT处理最佳,>0.25 mm团聚体含量(<i>R</i><sub>0.25</sub>)、平均重量直径(MWD)、几何平均直径(GMD)分别比RT处理增加5.8%、8.0%和13.0%,分形维数(<i>D</i>)降...
zh-cn
pair_31621236
The dynamic simulation of cucumber growth and development in sunlight greenhouse can provide technical support for the intelligent management of cucumber production. According to the cucumber response characteristics to light and temperature, the cucumber development module based on the algorithm of clock model was est...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
实现日光温室黄瓜生长发育动态模拟预测,可为日光温室黄瓜智慧生产管理提供技术支撑.本研究依据黄瓜生长发育的光温反应特性,以‘津优35’为试验品种,利用2年4茬分期播种试验观测数据建立基于钟模型的温室黄瓜发育模拟模型.依据温室黄瓜叶片生长与关键气象因子(温度和辐射)的关系,以辐热积(TEP)为自变量构建了黄瓜叶面积指数(LAI)模拟模型;依据单位叶面积光合作用对叶面积指数和日长的二重积分,结合黄瓜不同器官的呼吸消耗,构建了黄瓜干重生产分配模拟模型,结合器官含水量,构建了黄瓜器官鲜重模拟模块.基于各子模块构建了温室黄瓜生长发育模拟模型,确定了模型品种参数并进行检验.结果表明: 日光温室黄瓜移栽期-伸蔓期、移栽期-初花期、移栽期-采收初期和...
zh-cn
pair_31621238
Rehmannia glutinosa, a perennial herbaceous species, belongs to the family Scrophularia-ceae. As a staple medicinal material, its tuberous roots are highly valued in traditional Chinese medicine. However, R. glutinosa suffers from serious consecutive monoculture problems in production, which leads to a decline in both ...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
地黄为玄参科多年生草本药用植物,以块根入药,是我国著名的大宗药材.但是地黄在农业生产过程中存在严重的连作障碍问题,造成产量和品质急剧下降.细菌作为叶际微生物中最为丰富的一类,对宿主植物的生长发育与健康至关重要.叶际细菌区系研究为探索连作障碍形成机制及其消减措施提供了一个全新视角,同时差异菌群也可作为连作障碍发生的指示菌.本研究采用16S rDNA基因高通量测序结合传统可培养法分析地黄连作下叶际细菌群落结构及多样性变化.结果表明: 地黄连作导致叶际细菌群落结构发生明显变化,重茬地黄和病株地黄的叶际细菌群落结构较为相似,聚为一类,并明显区别于头茬地黄.同时,重茬地黄和病株地黄叶际细菌群落的均匀度指数、Shannon多样性指数、Simps...
zh-cn
pair_31621239
To explore the effects of Spartina alterniflora invasion in a seaward direction on variations of inorganic sulfur forms in marsh soils, the levels of inorganic sulfur forms (H<sub>2</sub>O-S, Adsorbed-S, HCl-Soluble-S and HCl-Volatile-S) were determined in bare flat (BF, before invasion), S. alterniflora marsh after se...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
选择闽江河口鳝鱼滩互花米草海向入侵前的光滩(BF)、入侵过程中(入侵1年)的互花米草湿地(SA′)以及入侵后(入侵3年)的互花米草湿地(SA)为研究对象,基于时空互代法,研究了互花米草海向入侵对湿地土壤无机硫赋存形态(水溶性硫H<sub>2</sub>O-S;吸附性硫Adsorbed-S;盐酸可溶性硫HCl-Soluble-S;盐酸挥发性硫HCl-Volatile-S)的影响.结果表明: 互花米草海向入侵不同程度改变了湿地土壤中各形态无机硫的赋存状况及空间分布特征.相对于BF,SA土壤中的H<sub>2</sub>O-S、Adsorbed-S和HCl-Volatile-S含量分别增加52.6%、78.2%和21.0%,而HCl-So...
zh-cn
pair_31621240
Ecological capital is an important fulcrum for the construction of ecological civilization. Measuring the spatial and temporal changes and influencing factors of ecological capital efficiency can help understand the current status of ecological capital efficiency and improve the level of ecological civilization to achi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
生态资本是生态文明建设的重要支点,测度生态资本效率的时空分异和影响因素,有助于了解生态资本效率现状进而提升生态文明水平实现绿色发展.选取东北地区作为研究区域,运用超效率数据包络分析法(DEA)模型和Malmquist指数测度东北地区生态资本效率的时空变化并对影响因素进行分析.结果表明: 东北地区生态资本效率总体良好,呈现先升后降的趋势,黑龙江生态资本效率较高,呈“U”型发展,吉林、辽宁生态资本效率相对较低.Malmquist指数分析显示,技术进步是生态资本效率提升的主要推动力量.Tobit回归分析结果表明,环境的规模效应、人口结构效应变量对生态资本效率具有显著的正向影响,科技投资效率低导致环境技术效应变量与生态资本效率呈负相关.提高...
zh-cn
pair_31621243
Landslides are common geological calamities in mountainous regions, which not only threaten social and economic development and residents' safety but also cause ecosystem damage, with consequences on human welfare. A more comprehensive and systematic reference for disaster prevention and mitigation with ecosystem servi...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
滑坡是山地常见的地质灾害,不仅对社会经济和人身安全造成严重威胁,而且也会对生态系统造成破坏,进而影响人类福祉.滑坡生态风险评价过程中用生态系统服务表征生态系统的潜在损失,可以为防灾减灾提供更系统全面的参考.西南五省区(四川、云南、贵州、广西、重庆)地貌类型多样、地层岩性复杂、地质构造运动活跃,是我国滑坡灾害最严重的地区之一.本研究从灾害危险性、生态系统脆弱性、生态系统潜在损失3个维度构建了滑坡灾害生态风险评价框架、模型和指标,其中,危险性基于地质、地形、地貌、降水等因素及相互组合关系进行综合分析所得,脆弱性用景观格局指数表征,潜在损失用生态系统服务来衡量,进而对西南五省区的滑坡灾害生态风险进行评估,结果表明: 生态系统潜在损失较高的...
zh-cn
pair_31621245
To evaluate the effects of enhancement release of Chum salmon (Oncorhynchus keta) in Suifen River, the homing Chum salmon was monitored in Dongning section of Suifen River from 2012 to 2017. A total of 462 samples were collected, 41 samples out of which were tagged indivi-duals which were cut off adipose fin before the...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
为评估绥芬河大麻哈鱼增殖放流效果,本研究于2012—2017年在绥芬河东宁段对大麻哈鱼溯河洄游群体进行跟踪监测.共采集样本462尾,其中,标记个体(剪脂鳍)41尾.根据调查数据,计算了大麻哈鱼增殖放流回捕率,评估了增殖放流效果.结果表明: 2010—2012年的大麻哈鱼增殖放流回捕率为0.295%,大麻哈鱼增殖放流数量效益为1∶2.87.标记组和非标记组群体年龄组均为1<sup>+</sup>~5<sup>+</sup>龄,平均年龄分别为3.93和3.63龄.采用Logistic 曲线方程计算标记组和非标记组大麻哈鱼的50%初次性成熟叉长(<i>L</i><sub>50</sub>)分别为53.13和49.89 cm.ARSS分析结...
zh-cn
pair_31621246
Silver nanoparticle is widely used in the field of medicine because of its strong and effective antibacterial action. However, it has potential biological toxicity. In this study, the classical model organism, Drosophila melanogaster, was used to explore underlying mechanism for the toxic effects of silver nanoparticle...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
纳米银因具有强有效的抗菌作用而被广泛应用于医药领域,然而它存在潜在的生物毒性.本研究选取经典的模式生物黑腹果蝇,探究纳米银对生物体的毒性作用机理.测定不同浓度纳米银处理下的<i>Oregon R</i>、<i>w1118</i>、<i>MTF</i>突变体等品系的化蛹率、羽化时间、羽化率及寿命;用<i>rpr-lacZ</i>品系的lacZ活性测定不同纳米银浓度处理下翅成虫盘的细胞凋亡情况; 通过SDS-PAGE研究不同浓度纳米银浓度处理下<i>MTF</i>突变体中肠蛋白的表达差异,并利用质谱分析差异蛋白的氨基酸序列.结果显示: 纳米银处理浓度升高至200 μg·mL<sup>-1</sup>及以上时,<i>MTF</i>突变体化...
zh-cn
pair_31621247
Based on samples collected by bottom trawl in May, August, November and December 2016 in the Minjiang Estuary, species richness and functional diversity of fishes, as well as their spatial-temporal variations, were quantified by a trait-based approach. The functional diversity varied with the changes of species richnes...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
根据2016年春季(5月)、夏季(8月)、秋季(11月)和冬季(2月)在闽江口海域进行底拖网作业的渔业资源调查样品,应用鱼类形态功能特征点数据分析了福建闽江口海域的鱼类功能多样性现状及时空变异.结果表明: 功能多样性与物种丰度具有相同的变化趋势,各站位鱼类物种丰度分别为:春季(17.8±5.1);夏季(22.4±5.6);秋季(17.7±6.3);冬季(12.1±2.3).鱼类集群功能多样性指数夏季最高,为(33.94±28.70),冬季最低(9.93±8.83),春季为(11.30±7.55),秋季为(19.05±19.32).群落内功能种呈现显著的季节演替,春季为太的黄鲫(占比为26%),夏季为六指马鲅(26%),秋季为龙头鱼,...
zh-cn
pair_31621248
Mycorrhizae, formed through the colonization of soil mycorrhizal fungi into the roots of host plants, are common symbiosis in the terrestrial ecosystems. The establishment of mycorrhizae is mainly based on the bidirectional nutrient exchanges between the symbiotic partners. Mycorrhizal fungi can absorb mineral nutrient...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
菌根是陆地生态系统普遍存在的、由土壤中的菌根真菌侵染宿主植物根系形成的联合共生体.菌根的建立是以共生体双方的营养交换为基础的:菌根真菌从土壤中吸收氮、磷等营养物质并转运给宿主植物,供其生长;作为交换,植物则以脂质或糖的形式向菌根真菌提供其生长所必需的碳水化合物.近年来,菌根真菌与宿主植物间的营养交换机制一直是研究的热点,国内外对菌根真菌介导的植物营养物质吸收和转运机制的研究也取得了巨大进展.本文综述了丛枝和外生两种菌根真菌与宿主植物间营养交换的最新研究进展,尤其是碳、氮、磷等几种重要营养物质的吸收与双向转运机制,以及营养交换在菌根形成中的潜在调控作用,并对目前存在的关键问题和未来研究方向进行了分析和展望,这对菌根模型的建立及菌根效益...
zh-cn
pair_31621250
The visual communication between insect and plant is one of the key sensory signal channels for the survival, reproduction and defense of insects. The colored sticky boards, which are developed based on insects positive phototaxis and as one of the effective green pest control measures, have been widely applied for mon...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
昆虫与植物之间色彩通讯是彼此信息交流的渠道之一,基于害虫趋色性研发的诱虫板作为一种绿色防控手段,已广泛用于农林害虫的虫情监测、预测预报、大量诱杀以及天敌诱集和指引,效果良好.本文概述了昆虫趋光趋色机理、诱虫板诱杀害虫机制和诱虫板色彩、形状、大小、高度、密度、方向、诱虫时长、植株形态和害虫生理状态等对于诱捕效果的影响,总结了诱虫板在茶园、菜地和大棚等作物环境中的多种实用技术,解析了诱虫板与昆虫性诱剂、植物源引诱剂等配合使用方法及其功效,评价了诱虫板治虫的优缺点并提出改进措施,讨论了诱虫板诱效的评价方法和成本核算.展望了新一代诱虫板研发方向、诱虫板与信息素等产品在有害生物综合治理(IPM)中的集成应用和诱虫板产业前景.
zh-cn
pair_31621946
Species interactions matter to conservation. Setting an ambitious recovery target for a species requires considering the size, density, and demographic structure of its populations such that they fulfill the interactions, roles, and functions of the species in the ecosystems in which they are embedded. A recently propo...
en
lexi-ml/wmt_22_dataset_en_zh-cn
train
text
物种间的相互作用对保护至关重要。设定远大的物种恢复目标需要考虑其种群大小、密度和种群统计结构, 以确保物种能在其所处的生态系统中实现种间互作和物种自身的作用与功能。最近提出的《国际自然保护联盟 (IUCN) 绿色物种名录》框架正式纳入了这项需求, 提出从代表性、生存力和功能性三个方面来定义完全恢复的物种。从物种恢复的角度来定义和量化其生态功能, 在概念和应用上都具有挑战性, 但这也是在保护实践中引入生态学理论的重要机遇。我们提出了两种互补的方法来评估物种的生态功能: 一是直接确认, 即列出物种的互作、确定互作中涉及的生态学过程和其它物种, 并量化物种对该生态过程的贡献;二是消除法, 即通过排除功能性受损后的症状来推断功能, 这与红色...
zh-cn