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PMC1090567_F2_2056.jpg
What is the central feature of this picture?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F2_2061.jpg
What is the main focus of this visual representation?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F2_2054.jpg
What is shown in this image?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F2_2058.jpg
What is the principal component of this image?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F2_2049.jpg
What is the central feature of this picture?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F2_2055.jpg
Can you identify the primary element in this image?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F2_2057.jpg
What does this image primarily show?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F2_2050.jpg
What is shown in this image?
GSNO modulates GPCR signaling in a dose-dependent manner. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. GSNO was present at the indicated concentrations for 60 min during the GDP loading (step 2). Carbachol (CCh...
PMC1090567_F3_2070.jpg
What can you see in this picture?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2068.jpg
Describe the main subject of this image.
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2062.jpg
What is shown in this image?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2073.jpg
What's the most prominent thing you notice in this picture?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2066.jpg
What can you see in this picture?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2069.jpg
What key item or scene is captured in this photo?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2072.jpg
What stands out most in this visual?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2067.jpg
What is the dominant medical problem in this image?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2064.jpg
Can you identify the primary element in this image?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F3_2071.jpg
What is the central feature of this picture?
S-nitrosocysteine (CysNO) mimics the effects of GSNO in modulating GPCR signaling, whereas sodium nitroprusside (SNP) and 8-bromo cyclic GMP (8Br-cGMP) do not. [35S]GTPγS autoradiography was conducted using a 3-step protocol with DPCPX (10-6 M) present throughout steps 2 and 3, as detailed in the Methods section. Where...
PMC1090567_F4_2077.jpg
What's the most prominent thing you notice in this picture?
GSNO only marginally affect opiate related receptor (ORL1), μ opioid receptor (MOR) and adenosine A1 (Ado A1) receptors signaling in brain sections. [35S]GTPγS autoradiography was conducted using a 3-step protocol with adenosine deaminase (ADA, 1 U/ml) present throughout steps 2 and 3, as detailed in the Methods sectio...
PMC1090567_F4_2080.jpg
What key item or scene is captured in this photo?
GSNO only marginally affect opiate related receptor (ORL1), μ opioid receptor (MOR) and adenosine A1 (Ado A1) receptors signaling in brain sections. [35S]GTPγS autoradiography was conducted using a 3-step protocol with adenosine deaminase (ADA, 1 U/ml) present throughout steps 2 and 3, as detailed in the Methods sectio...
PMC1090567_F4_2082.jpg
What is the central feature of this picture?
GSNO only marginally affect opiate related receptor (ORL1), μ opioid receptor (MOR) and adenosine A1 (Ado A1) receptors signaling in brain sections. [35S]GTPγS autoradiography was conducted using a 3-step protocol with adenosine deaminase (ADA, 1 U/ml) present throughout steps 2 and 3, as detailed in the Methods sectio...
PMC1090567_F4_2079.jpg
Describe the main subject of this image.
GSNO only marginally affect opiate related receptor (ORL1), μ opioid receptor (MOR) and adenosine A1 (Ado A1) receptors signaling in brain sections. [35S]GTPγS autoradiography was conducted using a 3-step protocol with adenosine deaminase (ADA, 1 U/ml) present throughout steps 2 and 3, as detailed in the Methods sectio...
PMC1090567_F4_2081.jpg
What is being portrayed in this visual content?
GSNO only marginally affect opiate related receptor (ORL1), μ opioid receptor (MOR) and adenosine A1 (Ado A1) receptors signaling in brain sections. [35S]GTPγS autoradiography was conducted using a 3-step protocol with adenosine deaminase (ADA, 1 U/ml) present throughout steps 2 and 3, as detailed in the Methods sectio...
PMC1090567_F4_2075.jpg
Can you identify the primary element in this image?
GSNO only marginally affect opiate related receptor (ORL1), μ opioid receptor (MOR) and adenosine A1 (Ado A1) receptors signaling in brain sections. [35S]GTPγS autoradiography was conducted using a 3-step protocol with adenosine deaminase (ADA, 1 U/ml) present throughout steps 2 and 3, as detailed in the Methods sectio...
PMC1090567_F4_2078.jpg
What object or scene is depicted here?
GSNO only marginally affect opiate related receptor (ORL1), μ opioid receptor (MOR) and adenosine A1 (Ado A1) receptors signaling in brain sections. [35S]GTPγS autoradiography was conducted using a 3-step protocol with adenosine deaminase (ADA, 1 U/ml) present throughout steps 2 and 3, as detailed in the Methods sectio...
PMC1090580_F1_2083.jpg
What can you see in this picture?
Chest radiograph showing right upper lobe consolidation (cardiac silhouette is normal).
PMC1090580_F2_2084.jpg
What key item or scene is captured in this photo?
Chest radiograph bilateral alveolar opacities and cardiomegaly.
PMC1090580_F3_2085.jpg
What is the central feature of this picture?
Photomicrograph demonstrates large areas of necrosis with interspersed myocytes showing degeneration and regeneration [Hematoxylin & Eosin, original magnification × 33]. Inset shows photomicrograph demonstrating acid-fast bacilli [Ziehl-Neelson stain, original magnification × 33].
PMC1090582_F2_2087.jpg
What is the main focus of this visual representation?
Monolayers of MCF-7 and MEC-1 cells cultured in low-serum medium and treated or not with extracellular Tat101aa (100 ng/ml for 36 hours). Increased numbers of cells can be observed in Tat-treated cultures as compared to untreated control cultures. Phase contrast; microscopic fields taken with a 10× objective.
PMC1090582_F2_2089.jpg
What is the core subject represented in this visual?
Monolayers of MCF-7 and MEC-1 cells cultured in low-serum medium and treated or not with extracellular Tat101aa (100 ng/ml for 36 hours). Increased numbers of cells can be observed in Tat-treated cultures as compared to untreated control cultures. Phase contrast; microscopic fields taken with a 10× objective.
PMC1090582_F2_2086.jpg
What is the main focus of this visual representation?
Monolayers of MCF-7 and MEC-1 cells cultured in low-serum medium and treated or not with extracellular Tat101aa (100 ng/ml for 36 hours). Increased numbers of cells can be observed in Tat-treated cultures as compared to untreated control cultures. Phase contrast; microscopic fields taken with a 10× objective.
PMC1090582_F2_2088.jpg
What stands out most in this visual?
Monolayers of MCF-7 and MEC-1 cells cultured in low-serum medium and treated or not with extracellular Tat101aa (100 ng/ml for 36 hours). Increased numbers of cells can be observed in Tat-treated cultures as compared to untreated control cultures. Phase contrast; microscopic fields taken with a 10× objective.
PMC1090583_F3_2093.jpg
Can you identify the primary element in this image?
B. abortus predominantly invades into trophoblast giant cells in placenta. Placentas not used for bacterial culture were fixed in situ within uteri in 10% neutral buffered formalin and processed routinely for histologic examination and scoring using Meyer's hematoxylin stain. Specific labeling of B. abortus in placenta...
PMC1090583_F3_2091.jpg
What key item or scene is captured in this photo?
B. abortus predominantly invades into trophoblast giant cells in placenta. Placentas not used for bacterial culture were fixed in situ within uteri in 10% neutral buffered formalin and processed routinely for histologic examination and scoring using Meyer's hematoxylin stain. Specific labeling of B. abortus in placenta...
PMC1090583_F3_2092.jpg
What object or scene is depicted here?
B. abortus predominantly invades into trophoblast giant cells in placenta. Placentas not used for bacterial culture were fixed in situ within uteri in 10% neutral buffered formalin and processed routinely for histologic examination and scoring using Meyer's hematoxylin stain. Specific labeling of B. abortus in placenta...
PMC1090583_F3_2090.jpg
What is the central feature of this picture?
B. abortus predominantly invades into trophoblast giant cells in placenta. Placentas not used for bacterial culture were fixed in situ within uteri in 10% neutral buffered formalin and processed routinely for histologic examination and scoring using Meyer's hematoxylin stain. Specific labeling of B. abortus in placenta...
PMC1090590_F1_2094.jpg
What is the focal point of this photograph?
Magnified coronal T2-weighted MRI image of the right knee showing a medial meniscal tear.
PMC1090601_F1_2105.jpg
What is the main focus of this visual representation?
1A. Rho GTPase protein expression levels in the IBC cell line SUM 149 versus SUM 102. 1B. F-actin and focal adhesion distribution in SUM 149 and SUM 102 human breast cancer cell lines. 1A. Equal protein amounts were separated by 10% SDS-PAGE, transferred to nitrocellulose, and probed for RhoA, RhoC, and Rho (A, B, and ...
PMC1090601_F1_2095.jpg
What is the focal point of this photograph?
1A. Rho GTPase protein expression levels in the IBC cell line SUM 149 versus SUM 102. 1B. F-actin and focal adhesion distribution in SUM 149 and SUM 102 human breast cancer cell lines. 1A. Equal protein amounts were separated by 10% SDS-PAGE, transferred to nitrocellulose, and probed for RhoA, RhoC, and Rho (A, B, and ...
PMC1090601_F1_2101.jpg
What does this image primarily show?
1A. Rho GTPase protein expression levels in the IBC cell line SUM 149 versus SUM 102. 1B. F-actin and focal adhesion distribution in SUM 149 and SUM 102 human breast cancer cell lines. 1A. Equal protein amounts were separated by 10% SDS-PAGE, transferred to nitrocellulose, and probed for RhoA, RhoC, and Rho (A, B, and ...
PMC1090601_F1_2099.jpg
What is the core subject represented in this visual?
1A. Rho GTPase protein expression levels in the IBC cell line SUM 149 versus SUM 102. 1B. F-actin and focal adhesion distribution in SUM 149 and SUM 102 human breast cancer cell lines. 1A. Equal protein amounts were separated by 10% SDS-PAGE, transferred to nitrocellulose, and probed for RhoA, RhoC, and Rho (A, B, and ...
PMC1090601_F1_2098.jpg
What is shown in this image?
1A. Rho GTPase protein expression levels in the IBC cell line SUM 149 versus SUM 102. 1B. F-actin and focal adhesion distribution in SUM 149 and SUM 102 human breast cancer cell lines. 1A. Equal protein amounts were separated by 10% SDS-PAGE, transferred to nitrocellulose, and probed for RhoA, RhoC, and Rho (A, B, and ...
PMC1090601_F4_2109.jpg
What is the core subject represented in this visual?
Human breast cancer cell migration in response to wounding. SUM 149 and SUM 102 cells were grown to confluency on glass coverslips and wounded with a sterile razor blade. Closure of the wound was monitored over 7.5 hours. Cells were stained with rhodamine phalloidin to visualize F-actin reorganization in response to ce...
PMC1090601_F4_2108.jpg
What's the most prominent thing you notice in this picture?
Human breast cancer cell migration in response to wounding. SUM 149 and SUM 102 cells were grown to confluency on glass coverslips and wounded with a sterile razor blade. Closure of the wound was monitored over 7.5 hours. Cells were stained with rhodamine phalloidin to visualize F-actin reorganization in response to ce...
PMC1090601_F5_2110.jpg
What is the core subject represented in this visual?
5A. E-cadherin distribution in SUM 149 and SUM 102 human breast cancer cells. 5B. E-cadherin protein expression levels in the IBC cell lineSUM 149 versus SUM 102. 5A. Cells were grown to 60% confluency and stained with anti-E-cadherin (green). Arrows indicate cell-cell adhesions containing E-cadherin. Micrographs were ...
PMC1090601_F5_2112.jpg
What is the principal component of this image?
5A. E-cadherin distribution in SUM 149 and SUM 102 human breast cancer cells. 5B. E-cadherin protein expression levels in the IBC cell lineSUM 149 versus SUM 102. 5A. Cells were grown to 60% confluency and stained with anti-E-cadherin (green). Arrows indicate cell-cell adhesions containing E-cadherin. Micrographs were ...
PMC1097720_F2_2113.jpg
What is the core subject represented in this visual?
Example of immunohistochemistry for CA IX. Example of biopsy stained for CA IX (×100). This tumor showed a small positive percentage.
PMC1097720_F3_2116.jpg
Can you identify the primary element in this image?
Example of immunohistochemistry for GLUT-1. Example of biopsy stained for GLUT-1 (×40). This tumor was scored highly positive.
PMC1097720_F4_2114.jpg
Can you identify the primary element in this image?
Example of immunohistochemistry for GLUT-1. Example of biopsy stained for GLUT-1 (×40). This tumor showed a small positive percentage.
PMC1097722_F7_2122.jpg
What is the dominant medical problem in this image?
Nucleolar colocalization of 16.4.1-GFP and Rev-CFP. HeLa 16.4.1-GFP cells and control HeLa GFP cells were transiently transfected with a Rev-CFP expression plasmid. Nuclei were counterstained with Hoechst 33342. 3D-Maximum image projections of Z-stacks were deconvolved and processed by multichannel unmixing, applying i...
PMC1097722_F7_2118.jpg
What can you see in this picture?
Nucleolar colocalization of 16.4.1-GFP and Rev-CFP. HeLa 16.4.1-GFP cells and control HeLa GFP cells were transiently transfected with a Rev-CFP expression plasmid. Nuclei were counterstained with Hoechst 33342. 3D-Maximum image projections of Z-stacks were deconvolved and processed by multichannel unmixing, applying i...
PMC1097722_F7_2117.jpg
What is the principal component of this image?
Nucleolar colocalization of 16.4.1-GFP and Rev-CFP. HeLa 16.4.1-GFP cells and control HeLa GFP cells were transiently transfected with a Rev-CFP expression plasmid. Nuclei were counterstained with Hoechst 33342. 3D-Maximum image projections of Z-stacks were deconvolved and processed by multichannel unmixing, applying i...
PMC1097722_F7_2120.jpg
Can you identify the primary element in this image?
Nucleolar colocalization of 16.4.1-GFP and Rev-CFP. HeLa 16.4.1-GFP cells and control HeLa GFP cells were transiently transfected with a Rev-CFP expression plasmid. Nuclei were counterstained with Hoechst 33342. 3D-Maximum image projections of Z-stacks were deconvolved and processed by multichannel unmixing, applying i...
PMC1097722_F7_2119.jpg
What is shown in this image?
Nucleolar colocalization of 16.4.1-GFP and Rev-CFP. HeLa 16.4.1-GFP cells and control HeLa GFP cells were transiently transfected with a Rev-CFP expression plasmid. Nuclei were counterstained with Hoechst 33342. 3D-Maximum image projections of Z-stacks were deconvolved and processed by multichannel unmixing, applying i...
PMC1097722_F7_2123.jpg
What is the core subject represented in this visual?
Nucleolar colocalization of 16.4.1-GFP and Rev-CFP. HeLa 16.4.1-GFP cells and control HeLa GFP cells were transiently transfected with a Rev-CFP expression plasmid. Nuclei were counterstained with Hoechst 33342. 3D-Maximum image projections of Z-stacks were deconvolved and processed by multichannel unmixing, applying i...
PMC1097746_F3_2127.jpg
What does this image primarily show?
(A) Cell-cell adhesion- Epithelial cells were stained with anti-E-cadherin monoclonal antibody and detected by fluorescent dye microcopy. Green fluorescent represents E-cadherin molecules connecting cells. Red color represents nucleus. (B) Cell-matrix adhesion- Adherent endothelial cell was stained with anti-fibronecti...
PMC1097746_F3_2126.jpg
What is the focal point of this photograph?
(A) Cell-cell adhesion- Epithelial cells were stained with anti-E-cadherin monoclonal antibody and detected by fluorescent dye microcopy. Green fluorescent represents E-cadherin molecules connecting cells. Red color represents nucleus. (B) Cell-matrix adhesion- Adherent endothelial cell was stained with anti-fibronecti...
PMC1097755_F5_2129.jpg
What is the focal point of this photograph?
Fluorescence microscopy. L. donovani promastigotes transfected with a CPN10/GFP gene chimera on plasmid pIRCPN10::GFP were subjected to bright field microscopy at 63× magnification (panels A-C). The same microscopic fields were viewed under UV excitation at XXX nm (panels D-F). Panels G-I show the overlays.
PMC1097755_F5_2128.jpg
What is shown in this image?
Fluorescence microscopy. L. donovani promastigotes transfected with a CPN10/GFP gene chimera on plasmid pIRCPN10::GFP were subjected to bright field microscopy at 63× magnification (panels A-C). The same microscopic fields were viewed under UV excitation at XXX nm (panels D-F). Panels G-I show the overlays.
PMC1097755_F5_2134.jpg
What is the dominant medical problem in this image?
Fluorescence microscopy. L. donovani promastigotes transfected with a CPN10/GFP gene chimera on plasmid pIRCPN10::GFP were subjected to bright field microscopy at 63× magnification (panels A-C). The same microscopic fields were viewed under UV excitation at XXX nm (panels D-F). Panels G-I show the overlays.
PMC1097755_F5_2133.jpg
What is shown in this image?
Fluorescence microscopy. L. donovani promastigotes transfected with a CPN10/GFP gene chimera on plasmid pIRCPN10::GFP were subjected to bright field microscopy at 63× magnification (panels A-C). The same microscopic fields were viewed under UV excitation at XXX nm (panels D-F). Panels G-I show the overlays.
PMC1097755_F5_2135.jpg
What is the main focus of this visual representation?
Fluorescence microscopy. L. donovani promastigotes transfected with a CPN10/GFP gene chimera on plasmid pIRCPN10::GFP were subjected to bright field microscopy at 63× magnification (panels A-C). The same microscopic fields were viewed under UV excitation at XXX nm (panels D-F). Panels G-I show the overlays.
PMC1097755_F5_2130.jpg
What is shown in this image?
Fluorescence microscopy. L. donovani promastigotes transfected with a CPN10/GFP gene chimera on plasmid pIRCPN10::GFP were subjected to bright field microscopy at 63× magnification (panels A-C). The same microscopic fields were viewed under UV excitation at XXX nm (panels D-F). Panels G-I show the overlays.
PMC1097763_F1_2137.jpg
What is the core subject represented in this visual?
CT scan showing the gallbladder inflammatory mass
PMC1097763_F4_2138.jpg
What is being portrayed in this visual content?
Photomicrograph showing immunohistocemical negative staining with desmin (× 100)
PMC1110909_pbio-0030186-g001_2143.jpg
What is the principal component of this image?
The Mouse Sox1 βgeo Allele Reveals the Requirement of SOX1 in the Development of VS Neurons(A) Strategy for targeting of the Sox1 locus by insertion of βgeo. Restriction enzymes: RV, EcoRV; K, KpnI; E, EcoRI; S, SpeI; B, BamHI. Yellow boxes indicate βgeo, green, SOX1 exon, and blue lines indicate fragments appearing in...
PMC1110909_pbio-0030186-g001_2144.jpg
Describe the main subject of this image.
The Mouse Sox1 βgeo Allele Reveals the Requirement of SOX1 in the Development of VS Neurons(A) Strategy for targeting of the Sox1 locus by insertion of βgeo. Restriction enzymes: RV, EcoRV; K, KpnI; E, EcoRI; S, SpeI; B, BamHI. Yellow boxes indicate βgeo, green, SOX1 exon, and blue lines indicate fragments appearing in...
PMC1110909_pbio-0030186-g001_2146.jpg
What is the main focus of this visual representation?
The Mouse Sox1 βgeo Allele Reveals the Requirement of SOX1 in the Development of VS Neurons(A) Strategy for targeting of the Sox1 locus by insertion of βgeo. Restriction enzymes: RV, EcoRV; K, KpnI; E, EcoRI; S, SpeI; B, BamHI. Yellow boxes indicate βgeo, green, SOX1 exon, and blue lines indicate fragments appearing in...
PMC1110909_pbio-0030186-g001_2140.jpg
Describe the main subject of this image.
The Mouse Sox1 βgeo Allele Reveals the Requirement of SOX1 in the Development of VS Neurons(A) Strategy for targeting of the Sox1 locus by insertion of βgeo. Restriction enzymes: RV, EcoRV; K, KpnI; E, EcoRI; S, SpeI; B, BamHI. Yellow boxes indicate βgeo, green, SOX1 exon, and blue lines indicate fragments appearing in...
PMC1110909_pbio-0030186-g001_2142.jpg
What object or scene is depicted here?
The Mouse Sox1 βgeo Allele Reveals the Requirement of SOX1 in the Development of VS Neurons(A) Strategy for targeting of the Sox1 locus by insertion of βgeo. Restriction enzymes: RV, EcoRV; K, KpnI; E, EcoRI; S, SpeI; B, BamHI. Yellow boxes indicate βgeo, green, SOX1 exon, and blue lines indicate fragments appearing in...
PMC1110909_pbio-0030186-g001_2147.jpg
What is the central feature of this picture?
The Mouse Sox1 βgeo Allele Reveals the Requirement of SOX1 in the Development of VS Neurons(A) Strategy for targeting of the Sox1 locus by insertion of βgeo. Restriction enzymes: RV, EcoRV; K, KpnI; E, EcoRI; S, SpeI; B, BamHI. Yellow boxes indicate βgeo, green, SOX1 exon, and blue lines indicate fragments appearing in...
PMC1110909_pbio-0030186-g006_2159.jpg
What is shown in this image?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2160.jpg
What is the central feature of this picture?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2158.jpg
What's the most prominent thing you notice in this picture?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2155.jpg
What is the core subject represented in this visual?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2149.jpg
What does this image primarily show?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2156.jpg
What is the core subject represented in this visual?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2154.jpg
What is the dominant medical problem in this image?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2150.jpg
What is the dominant medical problem in this image?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2152.jpg
What is the dominant medical problem in this image?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2153.jpg
What can you see in this picture?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1110909_pbio-0030186-g006_2157.jpg
What's the most prominent thing you notice in this picture?
SOX2 and SOX3 Down-Regulation in LGE Neurons and SOX1/SOX2 Co-Expression in LGE PrecursorsImmunofluorescence of coronal sections at LGE levels in (A–C) E15- and (D–L) E13-stage wild-type embryos visualized on a confocal microscope: antibody staining for (A, D, G, and J) SOX1 (red), (B, E, H, and K) SOX2 (green), (C) SO...
PMC1112593_F2_2163.jpg
What is being portrayed in this visual content?
F41D9.1::GFP expression. Widespread through the neural system. Panel A shows the general expression pattern in an L1 stage animal. Many cells in the nerve ring, the ventral nerve cord (vnc) and the tail region express GFP. Panel B presents the tail region in greater detail, scanning through the animal at three focal pl...
PMC1112593_F3_2176.jpg
What is the focal point of this photograph?
C17E4.3::GFP reporter expression. Present in the head and tail regions of larval stages. Panel Ai shows an overview of an L1 animal, with distinct cells near the anterior pharyngeal bulb as well as in the tail. Close up of the head reveals GFP expressing cells (Panel Bii), including muscle cells located in the posterio...
PMC1112593_F3_2170.jpg
What can you see in this picture?
C17E4.3::GFP reporter expression. Present in the head and tail regions of larval stages. Panel Ai shows an overview of an L1 animal, with distinct cells near the anterior pharyngeal bulb as well as in the tail. Close up of the head reveals GFP expressing cells (Panel Bii), including muscle cells located in the posterio...
PMC1112593_F3_2169.jpg
What is the focal point of this photograph?
C17E4.3::GFP reporter expression. Present in the head and tail regions of larval stages. Panel Ai shows an overview of an L1 animal, with distinct cells near the anterior pharyngeal bulb as well as in the tail. Close up of the head reveals GFP expressing cells (Panel Bii), including muscle cells located in the posterio...
PMC1112593_F3_2165.jpg
What is being portrayed in this visual content?
C17E4.3::GFP reporter expression. Present in the head and tail regions of larval stages. Panel Ai shows an overview of an L1 animal, with distinct cells near the anterior pharyngeal bulb as well as in the tail. Close up of the head reveals GFP expressing cells (Panel Bii), including muscle cells located in the posterio...
PMC1112593_F3_2168.jpg
What object or scene is depicted here?
C17E4.3::GFP reporter expression. Present in the head and tail regions of larval stages. Panel Ai shows an overview of an L1 animal, with distinct cells near the anterior pharyngeal bulb as well as in the tail. Close up of the head reveals GFP expressing cells (Panel Bii), including muscle cells located in the posterio...
PMC1112593_F3_2175.jpg
What can you see in this picture?
C17E4.3::GFP reporter expression. Present in the head and tail regions of larval stages. Panel Ai shows an overview of an L1 animal, with distinct cells near the anterior pharyngeal bulb as well as in the tail. Close up of the head reveals GFP expressing cells (Panel Bii), including muscle cells located in the posterio...
PMC1112593_F3_2166.jpg
Can you identify the primary element in this image?
C17E4.3::GFP reporter expression. Present in the head and tail regions of larval stages. Panel Ai shows an overview of an L1 animal, with distinct cells near the anterior pharyngeal bulb as well as in the tail. Close up of the head reveals GFP expressing cells (Panel Bii), including muscle cells located in the posterio...
PMC1112595_F3_2178.jpg
What is the core subject represented in this visual?
A section of CT scan of chest performed 8 days after hospitalization showing bilateral consolidation of lungs, mainly of lower lung fields.
PMC1112595_F3_2177.jpg
What is shown in this image?
A section of CT scan of chest performed 8 days after hospitalization showing bilateral consolidation of lungs, mainly of lower lung fields.
PMC1112595_F5_2179.jpg
Can you identify the primary element in this image?
Wet preparation of sputum [25% NaOH with 5% Glycerol as the mounting medium, 40× magnification] showing budding yeast [blastocyst]
PMC1112608_F1_2180.jpg
What can you see in this picture?
Hyperintensity of the nodule on T1- and T2-weighted images (left), which remains so after gadolinium injection (right), on T1-weigthed image in the portal phase.
PMC1112608_F1_2181.jpg
What stands out most in this visual?
Hyperintensity of the nodule on T1- and T2-weighted images (left), which remains so after gadolinium injection (right), on T1-weigthed image in the portal phase.
PMC1112608_F1_2182.jpg
What is the central feature of this picture?
Hyperintensity of the nodule on T1- and T2-weighted images (left), which remains so after gadolinium injection (right), on T1-weigthed image in the portal phase.
PMC1112608_F3_2184.jpg
Can you identify the primary element in this image?
Septal fibrosis in non tumoral liver (a), contrasting with absence of fibrosis in the nodule (b). Masson's trichrome.
PMC1112608_F4_2187.jpg
What is the main focus of this visual representation?
Septal fibrosis in non tumoral liver (a), contrasting with absence of fibrosis in the nodule (b). Reticulin staining.
PMC1112608_F4_2186.jpg
What object or scene is depicted here?
Septal fibrosis in non tumoral liver (a), contrasting with absence of fibrosis in the nodule (b). Reticulin staining.
PMC1112608_F6_2188.jpg
What's the most prominent thing you notice in this picture?
PAS staining: (a) foci of clear hepatocytes (arrow) close to the border between the non tumoral PAS positive zone, on the left side, and the PAS negative nodule on the right side of the photograph; (b) a clear focus in the nodule.