image
stringlengths
37
84
question
stringlengths
9
255
answer
stringlengths
1
1.79k
splits/sfolder_2/PMC3880045_F3_256274.jpg
Illustrate the image through a descriptive explanation
Observation of Serratia sp. LCN-16 in association with Bursaphelenchus xylophilus after 1 h and 24 h contact. (A, B) Differential interference contrast (DIC) microscope images of B. xylophilus, treated by 1 h contact of bacteria before (A) and after (B) washing with sterile DW. (C-F) DIC and fluorescence-merged images of B. xylophilus, treated by 24 h contact of bacteria and washed with sterile DW. The images of the head (C) and tail (D) region were captured in a single focal plane . Serial-section images were acquired and stacked, showing surfaces of the head (E) and tail (F) region. Scale bars, (A), (B), 30 μm; (C)-(F), 20 μm.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0lbwzddp20086u7z026z6z.jpg
Is there a green/black box artefact?
No
roco-dataset/data/train/radiology/images/ROCO_81378.jpg
Summarize the visual content of the image.
Lower second premolar tooth (#29). Age 48, male patient.
splits/subfolder_4/PMC3828594_f06_243445.jpg
Offer a thorough analysis of the image
Visualisation of CX3CL1 in dermal lymphatics of contact-hypersensitised mouse skin. (A) Whole-mount sections of control contralateral uninflamed ear skin and inflamed ear skin from mice subjected to topical oxazolone-stimulated skin hypersensitivity, permeabilised and stained for CX3CL1 (red) and podoplanin (green). Scale bars: 100 µm. Representative images from four mice are shown. (B) Whole-mount sections of inflamed ear skin were prepared in either the absence or presence of Triton X-100 (non-permeabilised and permeabilised, respectively), immunostained as above and imaged by confocal microscopy as a Z-series. Single planes of view are shown in left-hand panels; orthogonal views of different vessels in right-hand panels.
splits/subfolder_4/PMC2584033_F9_30158.jpg
Give an elaborate explanation of the image you see
Electron micrographs of myelinated axons in NFL-/- mice. Obvious twist of myelinated axons can be observed (A). Accumulation of mitochondria in the axon (A, arrow) and accumulation of amorphological cytoplasm materials between myelin sheath and axon (A, asterisk) were found near the node of Ranvier. Some mitochondria became enlarged and vacuolated (B, asterisks). An obvious accumulation of mitochondria could be detected in certain region of axons (C, arrow), which may lead to a giant axonal sphere stuffed with mitochondria (D). Note the large number of mitochondria that were vacuolated. (A and B from mice at age of 2 months, C and D from mice at age of 6 months).
roco-dataset/data/train/radiology/images/ROCO_80624.jpg
Relay a brief, clear account of the picture shown.
60-year-old female with squamous cell carcinoma who presented with left lower lip hypoesthesia. Sagittal view of the computed tomography scan showing cortical irregularity with periosteal reaction of the medial aspect of the left mandible (white arrow).
splits/sfolder_1/PMC2229647_pone-0001614-g001_17191.jpg
Analyze the image in a comprehensive and detailed manner
Histopathology of the small intestine.H&E-stained tissue sections of duodenum and proximal jejunum from rhesus macaques with idiopathic diarrhea. (A) Normal control duodenum from an age-matched rhesus macaque illustrating characteristic morphology of the villi. 100× magnification. (B) Enteropathy of duodenum. Diffuse enteritis characterized by shortening of villi, severe lymphocytic and plasmacytic infiltration of the lamina propria, and vacuolar degeneration of the epithelium. 100× magnification. (C) Normal control jejunum from an age-matched rhesus macaque. 100× magnification. (D) Enteropathy of jejunum. The mucosa appears flat with marked blunting of villi and dense infiltration of lamina propria by mononuclear cells. 100× magnification.
splits/subfolder_4/PMC3915066_F4_264726.jpg
What is shown in this image?
Postoperative coronal (A) and axial (B) views of contrast CT scan of the patient six months after tumor removal via exclusively endoscopic transnasal surgery
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0lbwy8dnt0086u6s76de6j.jpg
Are there any instruments in the image?
Tube
roco-dataset/data/train/radiology/images/ROCO_79248.jpg
Summarize the visual content of the image.
Hyperdense signal changes in dentate nucleus in bilateral serebellar hemispheres in axial T1 weighted images.
splits/subfolder_5/PMC3055888_pone-0017660-g001_89742.jpg
Give an elaborate explanation of the image you see
fgf10 expression pattern in early stages of chick lung development.Representative examples of whole mount in situ hybridization (A–C) and sections of hybridized lungs (D–F). fgf10 is expressed in the mesenchyme surrounding the emerging new buds (dark arrowheads) and in the distal mesenchyme surrounding the main bronchus (arrow); no epithelial expression is observed in either the main bronchus (open arrowhead) or in secondary buds (asterisks). Magnification: A - 6.3×; B/C - 5×; D/F - 10×.
splits/subfolder_4/PMC3039645_pone-0017070-g001_87324.jpg
Describe the following image in detail
Co-registered T1-weighted TFE, TOF, T2-weighted TSE, pre- and post-contrast T1-weighted TSE images of a transverse section of a plaque in the internal carotid artery.The right bottom panel displays the plaque components: red = lumen; green = outer vessel wall; yellow = LRNC; orange = calcifications; remaining vessel wall area = fibrous tissue. IPH was scored as being present (asterisk in T1-weighted TFE and TOF images) and the FC was designated as thin and/or ruptured (arrow in post-contrast T1-weighted TSE image).
splits/sfolder_1/PMC4451695_F8_392145.jpg
Give an elaborate explanation of the image you see
Detection of cell differentiations by higher magnification immunofluorescences at 6 weeks after Sk-34 cell transplantation. (A, arrows) SMA+/HNA+ cells located around blood vessel showing differentiation of engrafted human cells into vascular smooth muscle cells. (B, arrows) Anti-human CD31+/HNA+ cells were also observed around the blood vessel, showing differentiation into vascular endothelial cells. (C, arrows) NG2+/HNA+ cells located just around the mouse CD31+ blood vessel, showing differentiation into pericytes. (D, arrows) p75+/HNA+ cells were also located close to myelin (MBP+), showing differentiation into Schwann cells. F17-S, G, TA = Female 17 year-old, soleus, gastrocnemius, tibiaris aterior. Bars = 20 μm.
roco-dataset/data/train/radiology/images/ROCO_19881.jpg
Summarize the visual content of the image.
85-year-old woman on bisphosphonate therapy. Subtrochanteric femur fracture 10 weeks post operative fixation with an 11mm × 40cm reconstruction rod with 75 and 85mm screws proximally and a 65 mm locking screw distally (not included in this image). Exuberant callus is present at the fracture site (arrows).
splits/subfolder_4/PMC3093621_f0005_95105.jpg
Relay a brief, clear account of the picture shown.
Example of individual parameter data (R1, magnetization transfer – MT and R2*).
splits/sfolder_1/PMC3922251_F1_266563.jpg
Analyze the image in a comprehensive and detailed manner
Microscopic appearance of kidney sections according to age in Group M + C Crystal distributions are observed using polarized light optical microphotography (a-c), and scarring was noted with HE staining (d-f) of the paraffin-embedded axial sections in Group-M + C at day 28 in rats aged: 6 weeks (a, d), 10 weeks (b, e), and 26 weeks (c, f) (×20). Arrowheads indicate crystals, and arrows indicate scarring. Inset in (d) reveals the kidney scarring (×190).
splits/sfolder_3/PMC3417998_F1_149470.jpg
What is shown in this image?
Figure 1: CT scan showing a mass with solid and cystic components along with internal calcifications.
splits/subfolder_2/PMC4525691_fig-3_411955.jpg
Clarify the contents of the displayed image with great detail
T. rex (BHI 3033) cervical rib; photograph of the specimen in rostral-caudal view (A), XMT slices in medial-lateral (B), rostral-caudal (C) and transverse (D) views, and 3D rendering in medial-lateral view (E).Reactive bone is observed in some concentrated areas (red arrows). The high porosity consists of long canals running parallel to the long axis of the specimen (E in yellow). Scale bar is 5 mm.
splits/subfolder_3/PMC3559301_F1_182179.jpg
Share a concise interpretation of the image provided.
Three dimensional cine imaging and segmentation. Left column (A, C, E) show conventional 2D imaging with poor through-plane resolution. Right column (B, D, F) shows the high resolution segmentation that is possible using 3D single breath-hold imaging.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cla820gl8s40f071u27wyhkha.jpg
What type of procedure is the image taken from?
Colonoscopy
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cl8k2u1qy1ffv08325zl25biv.jpg
How many polyps are in the image?
1
splits/subfolder_2/PMC3940908_pone-0090431-g005_271087.jpg
Explain the various aspects of the image before you
Dynamic CT angiographic image (Axial, sagittal, 3-D reformat) demonstrates the development of a spot sign over the arterial, mid-cycle and venous phases in a subject with large right parasagittal frontal hematoma.It is notable how the spot temporally evolved in its size, shape, volume and density and then eventually faded at the end of venous phase.
splits/subfolder_3/PMC3857876_Fig1_250598.jpg
Illustrate the image through a descriptive explanation
Expression pattern of versican and lumican proteins in colon tumor epithelium and tumor stroma. Immunohistochemical staining patterns ranged from weak to strong epithelial and stromal staining for both versican and lumican. Representative examples of versican (a–c) and lumican (d–f) staining in colon tumor epithelium and stroma are shown. These examples were classified as negative (0), weak (1), moderate (2), and strong (3), with expression for epithelium (E) and stroma (S) indicated between brackets [E,S] as follows; a [1,1], b [2,3], c [3,1], d [0,1], e [2,1], f [3,2]. Scale bar = 50 μm
splits/subfolder_3/PMC3206476_F5_113920.jpg
Render a clear and concise summary of the photo.
Comparisons of radiograph processed by anisotropic diffusion with various alternatives. In this figure, the radiograph is diffused by different algorithm for comparison: (a) Original image (b) Gaussian filter (c) Average filter (d) Wiener filter (e) Symmetric Nearest Neighbor (SNN) filter (f) Anisotropic diffusion.
splits/subfolder_2/PMC3192669_F3_111593.jpg
Render a clear and concise summary of the photo.
At the level of sixth thoracic vertebra, CT scan shows marked sternal rotation (the sternum is rotated by almost 90 degrees) and depression, with a pectus index of 3.9.
splits/subfolder_2/PMC4553962_F3_418927.jpg
Give a short and clear explanation of the subsequent image.
(A) Pathological result (hematoxylin–eosin staining, original magnification: 10×). (B) Pathological result (hematoxylin–eosin staining, original magnification: 40×).
splits/subfolder_2/PMC4423933_pone.0125596.g003_384442.jpg
Narrate the contents of the image with precision
Rab27A deficiency did not affect the localization of zymogen granules, Rab27B and Rab3D.Pancreas tissues were cryosectioned at 10 μm, stained with phalloidin to label actin (green), DAPI to label nuclei (blue) and anti-amylase (A), anti-Rab27B (B) or anti-Rab3D (C) antibodies (red), respectively. Images were obtained using confocal microscopy. Each panel is paired with the Nomarski image for the same section. Scale bar = 25 μm.
splits/subfolder_4/PMC4493103_pone.0130556.g007_403418.jpg
Render a clear and concise summary of the photo.
CysP6 localizes to the ER. Agrobacterium the carrying plasmids pCysP6-YFP and pER-CFP (ER control) were infiltrated in Nicotiana benthamiana (A). The localization was visualized after 48 hours using confocal microscopy (B). CysP6-YFP was visualized in the networks of the ER and co-localizes with the control, ER-CFP. Scale bars, 15 μm.
splits/subfolder_3/PMC4022256_fig2_289007.jpg
Walk through the important details of the image
Comparison of FDG-PET changes over time between locally controlled versus uncontrolled tumors. The images represent raw tumor activities with window and level automatically set to reflect all activity values for the images at 12 minutes. The same settings are then applied to each corresponding image at 70 minutes from the same dynamic PET scan. (a) A locally controlled tumor. (b) A locally uncontrolled tumor. PET images prior to radiotherapy (0 Gy), at week 1 (10 Gy) and at week 4, (40 Gy) are shown as tumor activity at 12 min and 70 min (after injection).
splits/subfolder_2/PMC4505113_F1_406762.jpg
Provide a brief description of the given image.
Left image: axial T2 FLAIR showing 2 cm × 2.3 cm left frontal mass with substantial edema. Middle image: sagittal T1 post-contrast image showing contrast enhancement in a “ring-like” pattern. Right image: axial T2 FLAIR showing residual changes consistent with partial resection of the previous ring-enhancing left frontal mass.
ImageClef-2019-VQA-Med-Training/Train_images/synpic56357.jpg
what imaging modality was used to take this image?
mr - t1w - noncontrast
splits/subfolder_3/PMC3621843_F1_197723.jpg
Relay a brief, clear account of the picture shown.
Incidental left frontal cerebral arteriovenous malformation in a 65 year-old woman after 3 partial embolizations (patient #1). Maximum intensity projections of pre-operative dynamic 4D-MR angiography (a: frontal view, b: saggital view), treatment planning (c: fused DSA and planning target volume (PTV), d-f: fused CT with PTV and isodose lines).
roco-dataset/data/train/radiology/images/ROCO_39444.jpg
Offer a succinct explanation of the picture presented.
Coronal section of contrast-enhanced CT demonstrating contrast filling upwardly displaced caecum.
splits/sfolder_2/PMC4063128_fig1_299491.jpg
Describe the image concisely.
Broken hardware often poses a difficult problem and subsequent removal may increase surgical time and complexity of future surgeries. (a) shows an X-ray of an elbow (AP view) with broken and retained screws. (b) shows the same elbow in the lateral position.
roco-dataset/data/train/radiology/images/ROCO_35933.jpg
Render a clear and concise summary of the photo.
Postoperative retrograde urethrogram showing resolution of stricture following augmentation urethroplasty with buccal mucosa graft
splits/subfolder_4/PMC3060866_F4_90563.jpg
Portray the image with a rich, descriptive narrative
Time-lapse series on AMF live spores. Panels represent 5 min intervals in a time-lapse sequence monitoring nuclear migration into a developing spore of G. diaphanum by confocal microscopy. SytoGreen stained nuclei move unidirectionally into the spore. Images were acquired on xyt mode. Arrowheads indicate the first (white) and second (red) nucleus entering the spore. Note that some nuclei are out of focus in the xy optical section and can be difficult to visualize. Scale bar on the top-left panel represents 10 μm. Numbers on the top left of each panel are minutes.
roco-dataset/data/train/radiology/images/ROCO_15444.jpg
Relay a brief, clear account of the picture shown.
The CBD can be viewed in its entirety from the duodenal cap.
splits/subfolder_2/PMC4247298_f2-etm-09-01-0213_340124.jpg
Relay a brief, clear account of the picture shown.
Hematoxylin and eosin staining images showing the morphology of chondrocytes cultured in vitro with 0 μM (control), 5 μM (E-1), 10 μM (E-2) and 20 μM (E-3) epigallocatechin-3-gallate for 6 days. Cell seeding density, 2×104/ml; original magnification, ×100; scale bar = 200 μm.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxuo8zm8074ycugdbvq1.jpg
Are there any abnormalities in the image?
Oesophagitis
splits/subfolder_3/PMC4584485_Fig1_427310.jpg
Characterize the image using a well-detailed description
Compression of the inferior vena cava by foci of hepatic metastases. Computed tomographic scan of the abdomen and pelvis with intravenous contrast shows that the inferior vena cava (green arrows) becomes progressively more compressed by the tumor superiorly to inferiorly. a Patent inferior vena cava at the level of the pancreas. d Near-complete compression of the inferior vena cava at a level of the superior portion of the kidneys. a-d Superiorly to inferiorly
ImageClef-2019-VQA-Med-Training/Train_images/synpic39788.jpg
what is most alarming about this nuclear medicine image?
biliary leak, status post laparoscopic cholecystectomy
data_PathVQA/pathvqa_maml/t0/train_unlabel/train_2594.jpg
Does this image show thermal burn?
yes
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxvn90yk074ygz9h8gen.jpg
Is this finding easy to detect?
No
ImageClef-2019-VQA-Med-Training/Train_images/synpic45060.jpg
what organ system is shown in this mri?
skull and contents
splits/subfolder_3/PMC497042_F2_176.jpg
Portray the image with a rich, descriptive narrative
Optical Z-axis sections of caveolin-2 associated with chlamydial inclusion membranes. FRT cells were infected with C. trachomatis serovar K for 48 h. Cells were fixed with 10% cold methanol and double stained with a guinea pig anti-Chlamydia and a mouse anti-caveolin-2 antibody. The secondary antibodies were FITC-conjugated goat anti-mouse and TRITC-conjugated goat anti-guinea pig antibody. Slides were examined using a laser confocal microscope and optical Z-axis sections were taken at 0.5 μm depth and images merged using the Confocal Assistant™ version 4.02 Image Processing Software. Original magnification: 600X; the scale bar is 25 μm in length.
splits/subfolder_4/PMC4698822_Fig1_458561.jpg
Break down the elements of the image in a detailed manner
A 45-year-old man presented with glaucoma secondary to uveitis in his right eye (Case 9). Before surgery: a anterior segment photograph shows marked iris atrophy and pupillary occlusion. b slit lamp biomicroscopy examination revealed an extremely shallow anterior chamber. The central ACD was 0.261 mm. One week after surgery: c The image on the left demonstrates a quiet anterior chamber and a relative normal pupil. d The slit lamp photography shows a significantly deep anterior chamber. The central ACD has increased to 3.069 mm at the center after 23-gauge PPV and PPL
splits/subfolder_2/PMC2592545_pone-0003928-g003_30795.jpg
Share a comprehensive rundown of the presented image
Activation maps show similar BOLD activity in (a) FEF, SEF, and (b) LIP across subjects, m1 (session 2) and m2 (session 4), following caudal SC microstimulation.Activation maps are superimposed on coronal sections of structural T2-weighted MRI (p<0.05, corrected for multiple comparisons). The anterior-posterior coordinates relative to the anterior commissure for each section are (a) 1 mm and 4 mm, and (b) -21 mm and -20 mm for subjects' m1 and m2, respectively.
splits/subfolder_4/PMC3826580_fig3s1_242654.jpg
Write a terse but informative summary of the picture.
Representative confocal images of spheres infected with control virus (Ad-RFP).(A) Representative confocal images of control virus (Ad-RFP) infected spheres after immunostaining with antibodies specific to mouse Neurog3, NEUROD1, NKX2.2, SST, and GHRL. Right: immunostaining to detect cells co-expressing SST and GHRL.DOI: http://dx.doi.org/10.7554/eLife.00940.009
splits/subfolder_3/PMC3160001_f1-cpath-1-2008-001_105810.jpg
Narrate the contents of the image with precision
Imaging findings of the patient. Axial diffusion-weighted imaging (DWI) of brain MRI reveals several small acute infarcts involving the frontal and parietal lobes, right corona radiata and dorsal putamen shown with bright signal in the distribution of the right MCA territory and in the territories of the posterior watershed area compatible with the area of the apparent diffusion coefficient (ADC) reduction (a–d). The 3D time-offlight (TOF) MR angiography demonstrates abrupt disruption in mid-segment of M1 of right MCA (e). Long TR sequences demonstrate high signal abnormality centered in the right temporal, occipital, and middle frontal lobes suggesting old ischemia or infarct on the right cerebral hemisphere (f–h).
splits/sfolder_1/PMC4355733_f9_366073.jpg
Write an exhaustive depiction of the given image
Confocal laser-scanning fluorescent images of RBE cells treated with lobaplatin (5 μg/mL) with and without CQ (20 μM) for 24 h.GFP-LC3 (green fluorescence) transfected RBE cells were labeled with Superior LysoProbe (IV) (1 μM, red fluorescence), and Hoechst 33342 (1 μg/ml, blue fluorescence). Cells were imaged on an inverted laser scanning fluorescent microscope (Olympus) using a 60 × oil immersion objective lens.
splits/subfolder_2/PMC3605067_F1_193597.jpg
Narrate the contents of the image with precision
Slit-lamp examination of the left eye. (A) Corneal irregularity with marked thinning of the central cornea is observed in June 2008. (B) Slit-lamp examination of the left eye after penetrating keratoplasty revealed a diffuse cloudiness of the corneal graft with stromal oedema (June 2009). (C) Slit-lamp examination of the left eye in November 2009 showed an epithelial defect on the central cornea, which did not heal despite intensive topical therapy with autologous serum. (D) The corneal graft is clear after the second repeat keratoplasty, and there are no signs of infection (February 2011).
splits/subfolder_2/PMC3081557_F0005_93244.jpg
Summarize the visual content of the image.
A coned view of a CXR of lung basis with HPS shows bibasilar nodular or reticulonodular opacities. These are seen in 5–13.8% of patients with CLD and 46–100% of patients with HPS. These opacities are shown to represent dilated lung vessels on computed tomography as shown
splits/subfolder_3/PMC3056370_F0002_89885.jpg
Break down the elements of the image in a detailed manner
Prostatic abscess – case 2. Axial T2W MRI of the prostate (A) shows high signal (arrow) in the central gland, in the left midzone. Axial T1W image (B) shows mixed signal intensity with peripheral hyperintensity (arrow). Axial, contrast-enhanced T1W image (C) shows a peripherally enhancing abscess (arrow). DWI (b=800) (D) shows restriction of diffusion (arrow) in the lesion. The corresponding ADC map (E) shows low signal (arrow)
splits/subfolder_4/PMC3940883_pone-0090387-g004_271055.jpg
Write an exhaustive depiction of the given image
Infiltration of immune cells and C3 deposit in the grafted human islets.Tissue samples of islet allograft bearing kidney in hu-NSG mice were collected at the time of islet allograft rejection. Sections were stained with H & E (a–b, e–f and i) and antibodies to human antigens: insulin (c and g, brown), CD45 (d and h, green), CD4 (j, green), CD8 (k, red), CD11b (l, green), CD66b (m, red), and C3d (n, brown). Arrow indicates the kidney capsule or the area around islet grafts. Red square indicates the site of the infiltration. Scale bar: 100 µm.
splits/subfolder_5/PMC2988055_F1_78947.jpg
Write an exhaustive depiction of the given image
The immune reconstitution inflammatory syndrome in a patient with human immunodeficiency virus and Mycobacterium tuberculosis coinfection. (A) Chest X-ray on admission. (B) Chest X-ray 3 weeks after initiation of antiretroviral therapy. (C) Computed tomography of chest showed a large lymphadenopathy in mediastinum (arrow). (D) Tc-99 m methylene diphosphonate whole body bone scan showed multiple increased radioactive lesions in the axial and appendicular skeleton. (E) The drained chylous left pleural effusion.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cla820gles4bj071u6rxicrf7.jpg
What color is the abnormality?
Pink, Red, White
splits/subfolder_4/PMC3596546_jbr-24-02-124-g003_191469.jpg
Give an elaborate explanation of the image you see
The MRI of a high grade glioma. A: A heterogeneous and slightly long T1 signal with unclear border was detected in the T1WI sequence at the transverse plane in the left frontal lobe. B: A heterogeneous and slightly long T2 signal with unclear border was observed in the T2WI sequence at the transverse plane in the left frontal lobe. An edema band existed around the tumor. C: A T1WI enhancement scan at the transverse plane showed a wreath-like and heterogeneous enhancement. D: A T1WI enhancement scanning at the sagittal plane showed a wreath-like and heterogeneous enhancement.
roco-dataset/data/train/radiology/images/ROCO_69201.jpg
Summarize the visual content of the image.
FLAIR image of brain
splits/subfolder_4/PMC3283475_F5_126505.jpg
Walk through the important details of the image
Histological analysis of tumor specimen. Hematoxylin and eosin staining (magnification × 100) in excised tumor tissues were conducted after treatment with different mixtures by intratumoral injection. Cell necrosis and hemorrhage with leukocyte infiltration in the tumors were observed from Group I to IV. No obvious pathological changes were shown from Group V to VIII.
splits/subfolder_3/PMC2500179_ppat-1000135-g001_26418.jpg
Narrate the contents of the image with precision
Visualization of densovirus infections in cultured An. gambiae cells.In IFA's, cells were counterstained with Evan's Blue (red fluorescence) to visualize cell morphology. A: wild-type AgDNV visualized in Sua5B cells by IFA (IFA positive control); B: Negative-stain TEM of AgDNV particles purified from Sua5B cell. Arrow denotes unpackaged virion. Bar = 20 µm. C: Lack of natural densovirus infection in Moss55 cells (IFA negative control); D: densovirus visualized in Moss55 cells by IFA after transfection with pBAg; E: live-cell epifluorescence showing no fluorescence in untransfected Moss55 cells (epifluorescence negative control); F: live-cell epifluorescence showing cytoplasmic EGFP expression in Moss55 cells transfected with pBAg and pAgActinGFP.
splits/subfolder_3/PMC3765347_F5_229941.jpg
Give a short and clear explanation of the subsequent image.
Radiograph of a bony skier’s thumb.
splits/subfolder_3/PMC2822414_F0001_56794.jpg
Describe the image concisely.
Myrian Pro® software with CT scan images and three dimensional reconstruction of the rabbit body (bottom right image)
splits/subfolder_3/PMC3568125_pone-0055201-g003_184754.jpg
Narrate the contents of the image with precision
Double-labeling of CD90/Thy-1 with established lymph vessel markers.A–C) Cryostat section. Podoplanin and LYVE-1 not only label lymph vessels (arrowheads) but also other cell types in the murine lung. D–F) Precision cut lung slice. Double-labeling of LYVE-1 with CD90/Thy1 shows that a lymph vessel (arrowheads) is labeled by both antibodies but staining of other cells prevents identification of lymph vessels in the alveolar region (arrow). G–I) Precision cut lung slice. Co-labeling with antibodies against VEGF R3 and CD90/Thy-1 shows colocalization in lymph vessels in the alveolar region (arrowheads) but the antibody to VEGF R3 binds to other structures in the alveolar region.
splits/subfolder_4/PMC3565311_f6-ijms-14-01119_183987.jpg
Characterize the image using a well-detailed description
Leaf morphology of wild-type and ectopic overexpression of EsCRC in tobacco. The low magnification pictures provide an overview of (A1) abaxial and (B1) adaxial surfaces in wild-type tobacco, while high magnification pictures show cell shape, size and type on (A2) abaxial and (B2) adaxial surfaces of wild-type tobacco. Low and high magnification pictures of tobacco leaves with overexpression of EsCRC show (C1, C2) abaxial and (D1, D2) adaxial surfaces with more irregular cell surface and disordered cell arrangement.
splits/subfolder_4/PMC3685568_F6_212011.jpg
Share a comprehensive rundown of the presented image
Effect of paclitaxel and SB-T-1216 on cellular distribution of caspase-2 in SK-BR-3 cells. Control cells were incubated without taxane. After 36 h of incubation with tested taxane (100 nM), the localization of caspase-2 and DNA position were detected using confocal microscopy, following staining with DAPI (DNA) and indirect immunofluorescence staining (caspase-2) with antibody against human caspase-2 (see “Materials and Methods”). The localization of caspase-2 (green), of DNA (blue) and the merge of caspase-2 and DNA within the cell are shown. The data shown were obtained in one representative experiment of two independent experiments.
splits/sfolder_1/PMC4528794_fig1-2324709613494008_413032.jpg
Offer a succinct explanation of the picture presented.
(A) Preoperative magnetic resonance image before the patient’s first surgery at our institution showing contrast-enhancing cavernous sinus-based lesion. (B) Hematoxylin and esosin staining consistent with pituitary adenoma. (C) Positive synaptophysin labeling. (D) Absence of microopthalmia transcription factor labeling.
roco-dataset/data/train/radiology/images/ROCO_06903.jpg
Describe the image concisely.
Computed tomography image showing pulmonary embolism.
splits/subfolder_2/PMC3540089_pone-0053378-g003_177713.jpg
Portray the image with a rich, descriptive narrative
Scanning electron micrographs of rug1 leaves.(a, c) Adaxial surface of third-node leaves and (b, d–f) details of the adaxial epidermis. (e, f) Different magnifications of the area boxed in red in (c), which corresponds to a necrotic sector. Pictures were taken 21 das (days after stratification). Bars = (a, c) 1 mm, (b, d, e) 100 µm, and (f) 10 µm.
splits/sfolder_2/PMC3880045_F3_256271.jpg
Explain the various aspects of the image before you
Observation of Serratia sp. LCN-16 in association with Bursaphelenchus xylophilus after 1 h and 24 h contact. (A, B) Differential interference contrast (DIC) microscope images of B. xylophilus, treated by 1 h contact of bacteria before (A) and after (B) washing with sterile DW. (C-F) DIC and fluorescence-merged images of B. xylophilus, treated by 24 h contact of bacteria and washed with sterile DW. The images of the head (C) and tail (D) region were captured in a single focal plane . Serial-section images were acquired and stacked, showing surfaces of the head (E) and tail (F) region. Scale bars, (A), (B), 30 μm; (C)-(F), 20 μm.
ImageClef-2019-VQA-Med-Training/Train_images/synpic34759.jpg
what is most alarming about this x-ray?
acromioclavicular joint separation
splits/sfolder_3/PMC3570124_f1-etm-05-02-0533_185016.jpg
Break down the elements of the image in a detailed manner
Case 1: Bilateral lower limb swelling and pain of 2 days’ duration, 7 days after filter implantation. (A) Occlusion of the infrarenal IVC and Vena Tech filter in the thrombus were displayed by cavogram. (B) Following implantation of an OptEase filter in the suprarenal IVC and recanalization using a guide wire, the venogram displayed a large thrombus in the IVC. (C) After 14 days of thrombolytic therapy, the amount of residual thrombus in the IVC was <10%. (D) The OptEase filter was retrieved through a femoral vein approach. IVC, inferior vena cava.
splits/subfolder_5/PMC4353750_f1-etm-09-04-1103_365368.jpg
Describe the following image in detail
Histopathological images. Tissue samples were preserved in 10% neutral buffered formalin, paraffin embedded, processed to slides, and stained with hematoxylin and eosin. Representative histopathological images are shown. (A) Normal, (B) model (STZ-induced DCM), (C) STZ + positive drug (captopril) and (D) STZ + rutin. Magnification, ×400. STZ, streptozotocin; DCM, diabetic cardiomyopathy.
splits/subfolder_3/PMC3735582_pone-0072039-g005_223282.jpg
Provide a detailed description of the given image
3D OPT imaging of DCX staining in the mouse brain.3D OPT of a DCX-stained single hemisphere are shown as optical slices. DCX staining is visible surrounding the lateral ventricle (A; i–iii) and in the subgranular zone of the dentate gyrus (A; iv). A cartoon shows the location of the slices. The chains of DCX migrating neuroblasts along the lateral ventricle can be visualized on the ventricle surface in 3D (B). In (C), a maximum intensity projection of a full brain shows cells migrating along the RMS to the olfactory bulbs (shaded green).
splits/subfolder_5/PMC1475638_F6_5609.jpg
Examine the image closely and share its details
mRNA expression of surfactant protein D, determined with in situ hybridization on formaldehyde fixed paraffin sections of rat lungs during normal postnatal development at birth (A), day 6 (C), 10 (E) and 14 (B) and after exposure to hyperoxia on day 6 (D) and 10 (F) at a 200-fold magnification. a = alveolus, br = bronchus, bv = blood vessel, s = saccule, tb = terminal bronchus.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxuw8zsk074ygc1iadn2.jpg
What color is the abnormality?
Pink, Red, White
splits/sfolder_1/PMC1257601_f3-ehp0113-000749_3461.jpg
Analyze the image in a comprehensive and detailed manner
Histologic analysis of the Pb effects on fracture healing in group B mice continuously exposed to Pb in drinking water for 6 weeks (n = 6/group). See “Materials and Methods” for details. ABH/OG histology sections are shown at 10× magnification. Note the large amount of Alcian blue–stained cartilage in the day-14 fracture callus of Pb-treated mice (E, F). The immature fracture callus has less cartilage and exhibits a more advanced stage of remodeling in the unexposed animals (D).
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cl8k2u1qj1exf0832aav65cug.jpg
How many findings are present?
1
splits/subfolder_2/PMC4490402_f1_402504.jpg
Offer a thorough analysis of the image
AO correction via direct wavefront sensing improves morphological imaging deep inside the cortex of a living mouse.(a) 120 × 120 μm field-of-view single-plane TPE fluorescence images of neurons in a Thy1-YFPH mouse at 600–620 μm below pia after AO correction. Scale bar, 20 μm. (b) TPE fluorescence images of dendrites at 606, 606.5 and 608.5-μm depth taken with objective correction ring adjustment only (left) and correction ring adjustment plus AO (right). Scale bar, 5 μm. (c) SH sensor image (left) for an NIR GS produced by TPE excitation of directly injected ICG, and the corresponding corrective wavefront (right). Representative images from >500 image sections in five mice.
splits/subfolder_2/PMC4048157_pone-0097806-g007_295332.jpg
Examine the image closely and share its details
GFP expression pattern in Tg(gtshβ::GFP) larvae and adults.(A–I) show the lateral view (A, B, C, D and H) and the dorsal view (E–G, I) of Tg(gtshβ::GFP) larvae and adults from 3 dfp to 30 dfp. (J) The Tg(gtshβ::GFP) adult kidney section stained with DAPI (red). Bar = 100 µm (K) The higher magnification in the boxed area of J. Bar = 10 µm.
splits/subfolder_4/PMC2813108_F0003_55640.jpg
Summarize the visual content of the image.
Radial probe EBUS showing the peripheral pulmonary nodule as a hypoechoic structure
splits/subfolder_2/PMC4324644_pone.0117973.g001_357401.jpg
Provide a brief description of the given image.
The 57 ROIs used in the assessment of whole brain functional connectivity.The regions were identified according to a fully segmented rat brain atlas [39].
splits/sfolder_2/PMC2680324_fig02_38237.jpg
Narrate the contents of the image with precision
Phase-contrast images of hypha development of tetracycline-regulated conditional mutants after overnight growth on agar-slide cultures containing 1% (v/v) calf serum, under repressing conditions. vac1, vam2 and vam3 showed normal hyphal development. The vac7, vac8, fab1, ykt6 and vam9 mutants formed pseudohyphae under these conditions. The asterisk indicates yeast cells at the rear of the vam3 hypha. Scale bar represents 20 μm for all images.
splits/subfolder_2/PMC4324864_gou059-F2_357466.jpg
Explain the various aspects of the image before you
Sequential endoscopic therapy for T1a adenocarcinoma. A: T1a esophageal adenocarcinoma within Barrett s esophagus segment. B: Status following endoscopic mucosal resection (EMR). C: Three-month follow-up: squamous ingrowth at EMR site. D: Three-month follow-up: status following radiofrequency ablation (RFA). E: White light imaging: 36-month follow-up, status following two additional RFA and one additional EMR treatments. F: Narrow band imaging: 36-month follow-up, status following two additional RFA and one additional EMR treatments.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cla820gm1s56r071u92oy36ol.jpg
Are there any abnormalities in the image?
Ulcerative colitis
ImageClef-2019-VQA-Med-Training/Train_images/synpic35564.jpg
what imaging modality was used to take this image?
mr - t1w w/gadolinium
roco-dataset/data/train/radiology/images/ROCO_11436.jpg
Provide a brief description of the given image.
The choroidal thickness was measured manually with software assistance
splits/subfolder_2/PMC2803873_F1_54206.jpg
Summarize the visual content of the image.
Pre-operative anteroposterior and lateral radiographs of the patient showing medial unicompartmental prosthesis in-situ.
splits/subfolder_4/PMC2793371_fig9_52873.jpg
Characterize the image using a well-detailed description
Three-way model comparison: fixed-effects SPM analyses (p < 0.001 (uncorrected)). Heuristic, Total Power, and Frequency Response (3 bands). The voxel locations on the left correspond to the most significant cluster maximum after small volume correction with the BOLD activation mask (Talairach space). These F-maps show correlations between EEG and BOLD that are uniquely attributable to each model.
splits/sfolder_2/PMC3198696_F5_112594.jpg
Analyze the image in a comprehensive and detailed manner
Intracellular localization of occludin, ZO-1 and F-actin in the jejunum. Localization of the tight junction proteins occludin (top), ZO-1 (middle) and the actin skeleton protein F-actin (bottom) in jejunum of GvHD-mice (n = 26) and control animals (n = 16) were analysed by immunfluorescence microscopy. Representative results of independent examinations of 10 animals each group. Red arrows highlight alterations in the occludin and F-actin localization.
splits/subfolder_3/PMC4673219_F1_451632.jpg
Write an exhaustive depiction of the given image
Representative H&E and immunohistochemical staining of 7 candidate biomarkers in primary melanomas and metastatic melanomasCytoplasmic staining was investigated for BRAF, MMP2, Dicer, KAI1, and Tip60, and nuclear staining was observed for Fbw7 and p27. Metastatic melanomas had overexpression of BRAF and MMP2, but did not express/had low levels of Dicer, Fbw7, KAI1, p27 and Tip60 compared with primary melanomas. Magnification used × 400 for H & E and immunohistochemical staining. H & E, hematoxylin and eosin; IHC, immunohistochemistry; PM, primary melanoma; MM, metastatic melanoma.
splits/subfolder_3/PMC3887044_pone-0085419-g005_257805.jpg
Provide a detailed description of the given image
CD44 and SSEA4 co-staining distinguishes three types of colonies.Immunostaining of two independent reprogramming experiments at 23(i) and 26 days (ii) after transduction using antibodies against SSEA4 (magenta), and CD44 (green). The merged panel provides an overlay of the phase contrast image with both fluorescence signals. Both reprogramming experiments yield (A) CD44negative SSEA4positive colonies, (B) heterogeneous colonies, and (C) CD44positive SSEA4positive colonies (Scale bar: 200 µm).
splits/subfolder_4/PMC2503985_F3_26499.jpg
Share a concise interpretation of the image provided.
Images of the immunohistochemical assays: PECAM-1 on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days, and to control surface after (D) 24 hours, (E) 7 days and (F) 14 days.
data_PathVQA/pathvqa_maml/test/cell_sparse/train_1778.jpg
Is endocrine present?
yes
roco-dataset/data/train/radiology/images/ROCO_81364.jpg
What is shown in this image?
Axial computed tomography of the neck at the C1 level showing the two stents (large arrow) in cross section, side by side, in front of the C1 left lateral mass and behind the styloid process (small arrow).
splits/subfolder_3/PMC3731293_pone-0071514-g002_222125.jpg
What is shown in this image?
63-year-old woman with bilateral perineurial cysts on the T1 level (between T1 and T2).Sagittal section on T1- (A) and FST2-weighted (B) images with a view of the left lesion. Frontal T2-weighted section (C) and MR mielography (D). Axial T2-weighted (E) image.
splits/subfolder_5/PMC3471895_pone-0046641-g003_160272.jpg
Examine the image closely and share its details
Fluorescence-based cytotoxicity assay and chromatin condensation analysis.(A) Fluorescence-based cytotoxicity assay (using the LIVE/DEAD Viability/Cytotoxicity kit) of A431 and Hep2cells treated with TQ or DG for 24 or 48 hours. A significantly higher percentage of apoptotic cells (live (green)/dead (red)) are observed in the treated groups than in controls. (B) Fluorescence microscopic observation of A431 and Hep2 treated with IC50 of TQ and DG for 24 or 48 hours and stained with DAPI to detect chromatin condensation.
splits/sfolder_1/PMC3886883_pone-0084690-g007_257684.jpg
Clarify the contents of the displayed image with great detail
Deletion of gnt2 gene results in increased cell aggregation and aberrant septum morphology.(A) Light (upper panels) and fluorescence (lower panels) micrographs of GS II-FITC labelled swollen spores (after 3 h incubation in PDB) from wild type (wt), Δgnt2 mutant and cΔgnt2 complemented strains. Scale bars, 10 µm. (B) Transmission electron micrographs showing aggregation and ultra-structure characteristics of 14 h-old germlings from the indicated strains. Black arrows, septa; white arrows, cell-to-cell contact area; black star, extracellular matrix.
splits/subfolder_4/PMC4344797_Fig1_363164.jpg
Write an exhaustive depiction of the given image
How to measure the tumor extent. The longest diameter of a breast tumor was recorded using each modality; MMG (A), US (B), CT (C), MRI without CAD (D), MRI with CAD (E), and FDG-PET (F). For measurement of tumor extent with CAD, an enhancing tumor above the threshold was selected with the color overlay map, and then CAD-generated maximum tumor size was recorded.
ImageClef-2019-VQA-Med-Training/Train_images/synpic45536.jpg
what plane is demonstrated?
sagittal
data_PathVQA/pathvqa_maml/t0/train/cell_dense/train_1829.jpg
Does this image show thyroid, hashimoto 's?
yes