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splits/subfolder_2/PMC3579987_Fig12_187289.jpg
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a, b Transverse contrast-enhanced CT images acquired during the portal-venous phase at two different levels in a 55-year-old man with littoral cell angioma, which presents as multiple hypodense, partially contrast-enhancing, lesions of different size (arrows)
splits/subfolder_5/PMC3749607_fig4_226065.jpg
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Comparison of segmentation results on two X-ray vessel images. Column 1: original images. Column 2: the BCFCM algorithm. Column 3: the sFCM algorithm. Column 4: the CLIC algorithm. Column 5: the proposed algorithm. Column 6: the estimated bias fields by the proposed algorithm.
splits/sfolder_1/PMC4365027_pone.0120037.g005_369154.jpg
Explain the various aspects of the image before you
Contrast enhanced T1w image at (A) 48 hours post thermal ablation, inset is a close up of tumor with ADC map overlaid in color.Using the entire tumor from (A) as an ROI, we get (B) an average ADC for the tumor by fitting to a mono-exponential. Scale bar represents 2 mm. (C) Tumor ADC (mean over all animals). *: p < 0.0...
splits/sfolder_1/PMC4650435_fig3_445300.jpg
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BM-MSCs significantly enhanced the formation of autophagosomes and autolysosomes. (a) Immunofluorescence analysis was used to assess the number of LC3-positive (red) autophagosomes colocalized with LAMP2-labeled (green) lysosomes. White arrows point at the colocalization. Scale bar, 20 μm. (b) TEM analysis showed ultra...
splits/subfolder_2/PMC4414206_F3_381868.jpg
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Representative images showing tumor localization of 111In amatuximab and tumor expression of mesothelin in a 70 year old man with mesotheliomaCT (A), SPECT (B) and SPECT/CT (C) fusion image at 24 hours post-injection of 111In amatuximab showing mild uptake in the right pleural-based mass (arrows). High uptake in the li...
splits/subfolder_2/PMC4394550_ijms-16-06595-f004_377547.jpg
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Immunohistochemical detection of DAZL protein expression in chicken ESCs treated with various inducers of germ cell differentiation. (A) chicken ESCs with DMEM; (B) chicken ESCs with 10−5 mol/L ATRA induction; (C) chicken ESCs with 10−6 mol/L Am80 induction; (D) chicken ESCs with 1 μg/mL E2 induction. (400× magnificati...
splits/subfolder_5/PMC2807616_f3_55036.jpg
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Effects of dexamethasone on zonula occludens 1 and connexin 43 in normal trabecular meshwork cells. Fixed normal trabecular meshwork (NTM) cells were immunolabeled with zonula occludens 1 (ZO-1) and connexin 43 (Cx43) (green fluorescence) and observed under a confocal microscope, using identical parameters. The ZO-1 an...
splits/subfolder_3/PMC4114608_f3-ol-08-03-1169_309614.jpg
What is shown in this image?
Immunostaining of Wiskott-Aldrich syndrome protein family member 3 in non-small cell lung cancer samples; (A) adenocarcinoma and (B) squamous cell carcinoma (magnification, ×400).
roco-dataset/data/train/radiology/images/ROCO_01405.jpg
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Case 6: Magnetic resonance imaging axial section showing a well-defined enhancing lesion in the retromaxillary region.
splits/subfolder_3/PMC4101946_fig5_306833.jpg
What is shown in this image?
RE: complete resolution at biomicroscopy.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxus8zoo074yad840gix.jpg
How many findings are present?
2
splits/subfolder_4/PMC2566591_pone-0003378-g004_28727.jpg
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A–B, Immunohistochemistry for TH in the substantia nigra.High power view (10× and 20× magnification respectively) of TH-ir neurons in the substantia nigra employing the citraconic anhydride solution. Note the enhancement in the intensity and morphology (somas more preserved and processes more delineated) compared to th...
roco-dataset/data/train/radiology/images/ROCO_21528.jpg
Provide a brief description of the given image.
Sagittal endovaginal ultrasound of a cervical EP.
ImageClef-2019-VQA-Med-Training/Train_images/synpic36991.jpg
what plane is seen?
axial
splits/subfolder_4/PMC3522368_rootfig4_172935.jpg
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Mammography shows a uniformly dense mass.
splits/subfolder_2/PMC3414816_F3_149015.jpg
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Preoperative findings in case 2. (A) Anteroposterior radiograph reveals an osteonecrotic lesion in the left medial femoral condyle. (B,C) Coronal and saggital MRI shows an osteonecrotic lesion with high signal change on the T2-weighted image in the left medial femoral condyle.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cla820glis4jj071ub5c57d9g.jpg
Are there any abnormalities in the image?
Ulcerative colitis
splits/sfolder_1/PMC4348517_pone.0116692.g005_363730.jpg
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Averaged cortical activity evoked by acoustic stimulation examined by fMRI in all 3 groups.A—YC, b—MP, c—EP; group statistics, p = 0.05 with FWE correction; red—pink noise centered at 350 Hz and 700 Hz; blue—pink noise centered at 1.5 kHz, 3 kHz and 8 kHz. The arrowheads accentuate an increase in the right AC activatio...
roco-dataset/data/train/radiology/images/ROCO_31583.jpg
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Magnetic resonance imaging of both thighs consistent with myositis.
splits/subfolder_5/PMC4368423_pone.0120512.g006_370014.jpg
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Effect of AqE, AlE, CA and CI on protein expression of αSMA, Vimentin and ZO-1 by Immunofluorescence.ARPE-19 cells were seeded in chamber slides, treated with TGFβ1 or co-treated with TGFβ1 and various concentrations of AqE, AlE, CA and CI as indicated for 48 h. Cells were immunostained for αSMA (Red fluorescence), vim...
data_PathVQA/pathvqa_maml/t0/train_unlabel/train_2289.jpg
What is present?
multiple myeloma
splits/subfolder_3/PMC4432958_Fig7_386683.jpg
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Determination of uptake of Cy7-IO/HSA NPs by hBM-MSCs using Prussian Blue iron staining. Cells were grown in the absence (control, J) or presence of 10 ng/ml (A,C), 50 ng/ml (D,F)or 100 ng/ml (G,I) free FGF2 (A, D, G) or conjugated-FGF2 NPs (C, F, I) , or non-conjugated IO/HSA NPs at concentration of 9 μg/ml (B), 45 μg...
splits/sfolder_2/PMC4224021_Fig8_334056.jpg
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TLR2 immunopositive cells in the substantia nigra (SN) of control subjects, iLBD cases and PD patients. (a) Control subject showing few TLR2 positive cells (arrow), (b) an iLBD case showing widespread and numerous TLR2 positive cells (arrows) and (c) a PD patient, showing moderate numbers of TLR2 positive cells (arro...
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cla820gl8s41n071uanbv7xro.jpg
Where in the image is the abnormality?
Center, Upper-left, Upper-right, Lower-left, Lower-right, Center-left, Center-right, Upper-center, Lower-center
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxv5903w074y7k9dawqu.jpg
Is there a green/black box artefact?
No
splits/sfolder_2/PMC3905103_F1_262244.jpg
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55 degrees autofluorescence (A: Right eye & C: Left eye) and optical coherence tomography (B: Right eye & D: Left eye) performed 6 months after initial consultation. The OCT scan line location is shown as a green line in the autofluorescence images (A & C). The deposits that appeared drusen-like on clinical exam were h...
splits/sfolder_3/PMC4024188_F4_289560.jpg
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AR and ERα expression in the MPOA only partly overlaps with ARO expression. Brightfield photomicrographs of autoradiograms and schematic drawings of coronal sections from a female breeder illustrating the expression pattern of AR, ERα and ARO in the medial preoptic area. Shown are adjacent sections from the same female...
splits/subfolder_3/PMC4349238_Fig5_363932.jpg
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Fistulogram and ultrasound images of brachio-cephalic fistula. a: Fistulogram of Brachio-Cephalic AVF demonstrating a stenosis mid humerus (arrow). b: Doppler flow ultrasound of the AVF with large residual clot. c: Repeat ultrasound after tPA infusions resulted in decrease of clot burden.
splits/subfolder_4/PMC3666204_fig1_207515.jpg
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X-ray of image of rats in zinc disc implantation model of urolithiasis. (a) Control, (b) zinc disc implanted, (c) Cystone treated, (d) OA 60 mg/kg, (e) OA 80 mg/kg, (f) OA 100 mg/kg, and (g) ELC 200 mg/kg.
data_PathVQA/pathvqa_maml/val/illus_other/train_2674.jpg
What is present?
coronary artery anomalous origin left from pulmonary artery
splits/subfolder_5/PMC3723636_pone-0069712-g005_220122.jpg
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Mesothelia have varying abilities to migrate.Visceral mesothelial (A), parietal mesothelial (B), pleural mesothelioma (C), and peritoneal mesothelioma (D) cells were plated on fibronectin and subjected to time-lapse imaging in order to visualize their ability to migrate. Panels A–D are compilations of static images tak...
splits/subfolder_5/PMC3466321_pone-0045040-g018_159504.jpg
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Pseudocolor isosurface plots of the local membrane potential illustrating scroll-wave dynamics in a mural slice of our 3D simulation domain with a random distribution of myocytes and fibroblasts.We obtain three qualitatively different behaviors, namely, SRS (Single Rotating Scroll), MRSP (Multiple Rotating Scrolls), a...
splits/subfolder_2/PMC3311543_pone-0033722-g001_131358.jpg
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Axonal morphological changes demonstrated by in vivo tracing in the different brain areas after transient cerebral ischemia/reperfusion.Right panels were high magnification views of the areas in left panels in A–E (single arrow), respectively. Typical swollen axons or varicosities (arrowheads) could be seen in the prim...
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxve90k0074y15po5cmu.jpg
How many polyps are in the image?
0
splits/subfolder_3/PMC2901996_pone-0011492-g002_68476.jpg
Share a concise interpretation of the image provided.
Calvarial bone formation is defective in Osx-Cre: Hdac3 CKO mice.A–C. Staining of one day-old wildtype, het (Hdac3+/−:Osx-Cre−), and Hdac3 CKO mice with alizarin red and alcian blue. D. MicroCT reconstructions of skulls from 5.5 week-old wildtype, Het (Hdac3+/−: Osx-Cre+), and Hdac3 CKO mice.
splits/subfolder_4/PMC3573988_F5_185953.jpg
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Intracellular localization of high mobility group box chromosomal protein 1 in the hepatic tissues. Cells were double-stained with anti-high mobility group box chromosomal protein 1 antibodies and propidium iodide and analyzed by confocal microscopy. In the control cells, high mobility group box chromosomal protein 1 w...
data_PathVQA/pathvqa_maml/t0/train/inside_skull/train_1263.jpg
What removed ?
opened base of skull with brain
splits/subfolder_4/PMC3097768_F7_96098.jpg
Present a compact description of the photo’s key features.
Defining the bowel on treatment planning (a) T2 WI in sagittal plane followed by T2WI with fat saturation shows the bowel (arrow) clearly against the suppressed intra-peritoneal fat.
splits/subfolder_2/PMC4352940_fig2_365175.jpg
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Orthopantomographic view after trauma.
ImageClef-2019-VQA-Med-Training/Train_images/synpic33454.jpg
what is the plane?
frontal
data_PathVQA/pathvqa_maml/test/cell_sparse/train_1078.jpg
Is oral present?
yes
splits/subfolder_3/PMC3189131_F6_111132.jpg
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Immunofluorescence staining of NOTCH3 and HEYL. Immunofluorescence staining of NOTCH3 (green) and HEYL (red). Proliferating hemangioma, panels a-c; involuting hemangioma, panels e-g. NOTCH3+ cells are located in the perivascular regions and co-localize with HEYL (thick arrows, panels c & g). However, some endothelial c...
splits/subfolder_2/PMC3179305_fig01_109688.jpg
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Abnormal bone remodeling in the Dmp1 null mouse (Dmp1 KO, right panels), which is exacerbated with age. (A) Photographs of 3-day-old forelimbs stained with alizarin red/alcian blue showing that the KO cartilage is remodeled less than control. (B) Radiographs of 3-day-old hind limbs of Dmp1 control and KO images showing...
splits/subfolder_2/PMC3338496_pone-0035877-g002_135730.jpg
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Hematopoietic deficiency of miR155 promotes atherosclerotic lesion development in LDLR−/− mice.Representative pictures of toluidine blue-stained sections of the aortic root of wildtype (A) and miR155−/− (B) transplanted mice, magnification 40×. Hematopoietic miR155 deficiency increases plaque area (C) and promotes plaq...
splits/subfolder_4/PMC3423768_f4-rado-46-01-01_151129.jpg
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Volume rendered images of the dental pulp from Figure 3 in 18 different viewpoints 20° apart around the vertical axis. The shape of the pulp chamber, extent of pulp diverticles and the number of pulp canals are visualized with a high accuracy. Volume rendered images clearly demonstrate the complex anatomy of the dental...
splits/sfolder_1/PMC2246238_F3_17795.jpg
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(a) Bone cortex defect (arrows) on ultrasonography in a 63-year-old healthy control person on the radial side of the 3rd proximal interphalangeal joint in a longitudinal view. (b) The corresponding transverse view. (c) The coronal T1-weighted magnetic resonance image without contrast administration reveals no erosion-l...
splits/subfolder_2/PMC3514139_F2_170392.jpg
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Double immunostaining for Aβ42 (green fluorescence) and different subcellular markers (red fluorescence) in RA differenatiated SH-SY5Y cells. (A) Rab8 (Golgi derived vesicles marker), (B) Rab9 (trans-Golgi network, Golgi-derived vesicles and late endosome marker), (C) LAMP-2 (late endosome and lysosome marker), (D) Rab...
splits/subfolder_2/PMC3651531_Fig6_203923.jpg
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Combined Nile red and DAPI staining of DAOY (upper) and PFSK-1 (lower): a untreated cells at 0 h, b 10 μM cisplatin 24 h, c 10 μM cisplatin 48 h. The size bar is 5 μm
splits/subfolder_2/PMC3662089_F2_206349.jpg
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MRI of SKO acquired 9 years post-stroke, demonstrating an extensive left fronto-temporo-parietal lesion. Presented are a single sagittal slice, with nine coronal slices from anterior to posterior through the lesion area.
splits/sfolder_1/PMC4524636_pone.0135202.g004_411761.jpg
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Histology of hematoxylin and eosin (H&E) stained labyrinth of one wild-type (wt) three DNMT1o-deficient low-Peg10 gDMD methylation placentas.The scale bars for 50X, 100X and 200X magnification are 500, 200 and 100 μm respectively. Yellow lines in 50x and 100x magnification images outline the labyrinthine zone (LZ).
splits/subfolder_3/PMC3944744_F5_272225.jpg
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FE-SEM images. The magnifications of the images are (A) × 33,000, (B) × 150,000, and (C) × 160,000.
splits/sfolder_1/PMC4357899_f5_367076.jpg
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DAPI staining outside of tubules shows necrotic or apoptotic nuclei.Uptake of DAPI by Oct family cation transporters after 6 days in Sebinger culture either without (A) or with (B) Oct inhibitors metformin and cimetidine followed by staining with Cy5-conjugated Annexin-V. Annexin-V staining is associated with DAPI-posi...
splits/sfolder_1/PMC4526535_pone.0134558.g003_412313.jpg
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Photomicrographs of gastric mucosa stained with HE and PAS of the rats subjected to induction of chronic ulcer by 30% acetic acid.Animals were treated orally with 1% Tween-80 aqueous solution (control group), pantoprazole (40 mg/kg) or CIN (100 mg/kg) for 14 days. The filled arrow indicates the absence of the epithelia...
splits/subfolder_4/PMC2891704_pgen-1000995-g003_67325.jpg
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Brca2;Trp53 mutants have increased DNA damage and apoptosis.(A) Immunohistochemistry for γH2AX shows several cells have DNA damage in LG PIN areas in Brca2F/F;PBCre4 and Brca2F/F;Trp53F/+;PBCre4 mutant prostates, whereas control (Brca2F/F) prostates have undetectable levels of DNA damage. Brca2F/F;Trp53F/F;PBCre4 mut...
splits/subfolder_5/PMC3621816_f1-or-29-04-1299_197706.jpg
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Immunohistochemical profiles of ER, PR, HER2 and Ki-67 markers in the tumor sample from patient 1 (Patient 1); MACL-1-derived tumor xenograft in immunodeficient mouse (MACL-1 xenograft) and MACL-1-cultured cell line (MACL-1 cells). Scale bar, 100 μm.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cla820glys53z071u0kdfg268.jpg
How many findings are present?
1
splits/subfolder_5/PMC4263965_jpm-04-00402-f005_344092.jpg
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(A) Bone metastases aspirate smear. Wright-Giemsa stain; 600× magnification. The arrows point to some of the malignant cells in this field; (B) Bone metastases, high power: bone marrow biopsy. Hematoxylin and eosin stain; 400× magnification. A sheet of malignant cells at high magnification; (C) Bone metastases, synapto...
splits/subfolder_2/PMC3024221_F2_84886.jpg
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T1-weighted MR images and segmented contour plots showing Hemorrhage. (a) In vivo MR-images; (b) Segmented contour plots showing plaque components; (c) 3D geometry showing hemorrhage and other components.
roco-dataset/data/train/radiology/images/ROCO_29424.jpg
Summarize the visual content of the image.
Abdominal radiograph showing dilated small-bowel loops (Case 1).
splits/sfolder_2/PMC4623916_Fig4_438151.jpg
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Expression of Ghrelin in hypothalamus of each group. a Control group. b Model group. c XSLJZD-treated group. d Low-dose XSLJZD treated group. e Domperidone-treated group. Ghrelin distributed in cytoplasm of hypothalamus. (Tissue sections were viewed at 100× magnification.) Positive cells for Ghrelin were brown and circ...
data_PathVQA/pathvqa_maml/t0/train_unlabel/train_2866.jpg
What is present ?
hepatobiliary
data_PathVQA/pathvqa_maml/test/cell_sparse/train_2319.jpg
What does this image show?
surgical specimen
splits/subfolder_4/PMC3599251_F2_192282.jpg
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Group differences in subcortical regional brain volumes: superior view (A) and sagittal view showing the divisions for the corpus callosum (B). The larger volume in patients with neurofibromatosis type 1 (NF1) was observed in the left and right thalamus (green) and right caudate nucleus (blue) after controlling for tot...
splits/sfolder_3/PMC4648850_Fig2_444707.jpg
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Double-balloon enteroscopy showed an approximately 2-cm submucosal tumor in the jejunum at 100 cm from the incisor teeth
splits/subfolder_2/PMC3587996_f4-ijms-14-02449_189641.jpg
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An alveolar macrophage. Penetration of silver nanoparticles from aggregates in the cytoplasm into mitchondria. No silver nanoparticles are discovered in the nucleus. TEM, magnification 28,000×.
splits/subfolder_3/PMC4630636_f3_440102.jpg
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(a) Time-lapse image of the movement of the nuclei and the granules in the MARCO cell (Media 1). The nuclei move and disappear at 300 s, and reappear again at 450 s. The intracellular granules become concentrated in the circle region from 150 s. (b) Time-lapse image of the dynamic movement of the unstained single granu...
splits/subfolder_3/PMC4578006_mcv123-F5_425384.jpg
Explain the various aspects of the image before you
Spatial and temporal localization of superoxide (A, C, E) as contrasted to lignin (B, D, F) in grapevine buds during the first 3 h after transfer to 23 °C. Superoxide (NBT) is localized to latent meristem cells at 0 h, with negligible association with lignified cells (A–D, indicated by Auramine-O), where C and D are ma...
data_PathVQA/pathvqa_maml/t0/train/inside_lungs/train_1378.jpg
Is hyperplasia median bar present?
no
splits/subfolder_5/PMC4590420_RSFS20150012F1_428979.jpg
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Cubic membrane architecture. (a) Three-dimensional mathematical model representing the phospholipid bilayer of cubic membrane organization. (b) Two-dimensional transmission electron micrograph of the same three-dimensional model presented in (a). (c) Scanning electron micrograph and its corresponding (d) three-dimensio...
splits/subfolder_3/PMC2670517_pone-0005354-g002_37479.jpg
Summarize the visual content of the image.
Expression of Wnt5a and Fzd3, Fzd5, and Fzd6 in adult human hair follicles.Immunohistochemistry of paraffin-embedded skin samples was performed as detailed in Methods. Panels shown are at 200× magnification. The hair follicle schematic for the cartoon on lower right was adapted from [11].
splits/subfolder_3/PMC4374284_Fig4_371721.jpg
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These serial CT scans demonstrate the efficacy of re-treatment with everolimus 10 mg/d. The liver metastases remained stable during the period of re-treatment with everolimus for over 2 years.
splits/subfolder_2/PMC4662030_Fig2_448495.jpg
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Abdominal computed tomography (CT). a–c Post-enhancement CT shows a hyperdense mass of 2.62 × 5.70 cm in the right renal pelvis. This mass did not obstruct UPJ directly, and the ureter below the stone was dilated. a Transverse view. b Sagittal view. c Coronal view. d Another section of the transverse view of the CT sho...
roco-dataset/data/train/radiology/images/ROCO_22853.jpg
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Axial CT scan shows a triangular hard palate
splits/sfolder_1/PMC2913841_fig6_70381.jpg
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A 79-year-old male who received PDT for 27 months ago showed a recurrence of CNV (arrowheads), mainly at the temporal edge of the old scar (arrows) (a). Fluorescein angiography (FA) showed predominantly classic CNV (c), and optical coherence tomography (OCT) revealed a subretinal lesion before treatment (e). After the ...
splits/subfolder_5/PMC2714572_F0007_42029.jpg
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AP radiograph of the same patient with ARDS as in Figure 6 with further complication of bilateral pneumothoraces secondary to pleural drain placement
splits/subfolder_3/PMC4295575_Fig2_350704.jpg
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Magnetic resonance imaging scans showing the recurrence of the pituitary tumor. (A) Postoperative magnetic resonance imaging (MRI) scan taken in September 2008 (10 years after the first surgery) show no evidence of recurrence. (B) Postoperative MRI scan obtained in June 2009 show the recurrence of the tumor. (C and ...
splits/subfolder_4/PMC3542083_pcbi-1002849-g001_178368.jpg
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Computed Tomography (CT) scans of scleractinian coral Pocillopora verrucosa.(A) A controlled coral exposed to ambient current with the average near-bottom velocity of 5 cm s−1 [46]. (B) A coral that was grown in an in situ controlled flume setup with “reduced flow” condition (∼1 cm s−1) (C–E) Corals were grown in the ...
splits/sfolder_1/PMC4596022_F4_430591.jpg
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KC amplitudes vary across the cortex. A, The average amplitude of manual KCs at each channel, color coded by subject, is highly variable across the cortex. However, no significant effects are found when a linear mixed-effects model is applied. B, The addition of KC-like activity shows a similar pattern, but with the in...
splits/subfolder_3/PMC3210136_pone-0027148-g007_114488.jpg
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CDC-42, RAC and CDC-24 display partially distinct localization patterns in mature hyphal tips.Confocal laser scanning confocal microscopy of functional N-terminal fusion constructs of YFP-CDC-42 (A), YFP-RAC (B) and GFP-CDC-24 (C) reveal distinct localizations. CDC-42 localized as confined apical membrane-associated cr...
roco-dataset/data/train/radiology/images/ROCO_65544.jpg
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Severe subclavian artery stenosis before stenting.
splits/sfolder_2/PMC3882054_f7-0070119_256805.jpg
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Correct subcellular targeting of ClC-7/Ostm1 upon heterologous expression. (A) After transient transfection with rat ClC-7, either wild-type (WT) or the Y744Q mutant (MUT), HeLa cells were immunolabeled for ClC-7 (green in overlay) and the late endosomal/lysosomal marker protein LAMP-1 (red); blue in overlay indicates ...
splits/subfolder_3/PMC4146447_F1_315938.jpg
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Enhanced chest CT scan before operation. (A) In the coronal mediastinal window, preoperational CT scan showing the mass compressing the mediastinal vessels, heart and airway. (B) In the mediastinal window. (C) In the lung window.
splits/sfolder_2/PMC3341371_pone-0036188-g009_136347.jpg
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Electron microscopy of isolated human islets after 24 h incubation with glucose and/or palmitate. A) control; B 25 mM glucose; C) 0.5 mM PA; D) 25 mM glucose+0.5 mM pA (magnification: 10.000×; insert: 38.000×).
splits/subfolder_3/PMC3797294_f1-etm-06-04-1029_237831.jpg
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Histological observations. (A) Blank control; (B) epidermal keratinocytes of the normal mouse skin; (C) mouse skin epidermis following thermal stimulation. Immunostaining was used. The arrows indicate the skin epidermal keratinocytes where CAR may be expressed. Magnification, ×40.
splits/subfolder_4/PMC4176721_pone-0107979-g004_322854.jpg
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Increased demyelination in CSC-treated mice at day 14.Frozen sections of spinal cords were isolated from vehicle (saline/DMSO) and CSC-treated mice at day 14 and day 28 of EAE. Eriochrome cyanine (A) or fluoromyelin (B) was used to visualize demyelination. Areas of demyelination are indicated by diminished fluorescence...
splits/sfolder_2/PMC4506988_fig3_407421.jpg
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Live fluorescent Neobenedenia sp. attached to Lates calcarifer over time. Parasites observed attached to fish following 15 min (A), 30 min (B), 2 h (C), 48 h (D), 96 h (E) and 16 d (F) post-infection. Arrow shows the haptor of Neobenedenia sp. A slightly higher exposure was used when photographing parasites at 16 days ...
splits/subfolder_2/PMC4502305_fig2_405980.jpg
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Histological analysis (Masson's trichrome staining). Histological examination of the myocardium stained with Masson's trichrome (magnification ×100, scale bar: 100 μm). Data is presented as mean ± SEM. ∗ P < 0.05 versus W; # P < 0.05 versus GK; $ P < 0.05 versus W + MI. MI indicates myocardial infarction; GK: Goto-K...
splits/subfolder_3/PMC3892164_f01_258517.jpg
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Spatiotemporal pattern of accumulation of Hp-gad transcript, determined using whole-mount in situ hybridization.(A,a) Unfertilized eggs. (B,b) Fertilized eggs. (C,c) Morulae. (D,d) Swimming blastulae. (E–G,I) Double-stained whole-mount in situ hybridization. Hp-gad transcripts, red. Primary mesenchyme cells, green. (E)...
splits/subfolder_2/PMC2936090_F0002_73029.jpg
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(a) Preoperative photograph showing Ellis class III fracture in 21 with pulp exposure, (b) Preoperative radiograph revealing fracture in 21 with pulp involvement, (c) Partial pulpotomy performed in 21 and MTA placed over the exposed pulp, (d) Postoperative photograph, (e) Postoperative radiograph after two years showin...
data_PathVQA/pathvqa_maml/t0/train/illus_process/train_0910.jpg
Are histologic features negative for ER and HER2 triple negative ?
no
splits/subfolder_4/PMC3686068_fig2_212066.jpg
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Micrographs of periodic acid-Schiff (PAS) staining of rat kidneys. Light microscopy of sagittal half of kidney sections stained with PAS and counterstained with hematoxylin is shown (original magnification 200x for all panels). (a) Normal (ND), (b) T2DM treated with vitamin C (DM + vitamin C), (c) T2DM (DM), and (d) T2...
splits/subfolder_2/PMC3153919_fig3_104825.jpg
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Patient with 18 months of history of CSC in the right eye. (a) dots spots of leakage in the angiography; (b) standard FAF, showing diffuse superior hyperFAF; (c) NIA, showing three hypofluorescent spots around the macula, some of them corresponding exactly with the PEDs in (d) and (e); (d) and (e) SD-OCT exhibiting the...
data_PathVQA/pathvqa_maml/test/cell_sparse/train_1529.jpg
What is present?
female reproductive
splits/subfolder_3/PMC4074851_F2_302115.jpg
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MRI (Gd-EOB-DTPA MRI, hepatobiliary phase) and CT scans of a patient with CR. Monitoring of in vivo migration of 111In-oxine labeled dendritic cells with scintigraphy. MRI and CT scans revealed a liver metastatic lesion (arrow) (a, b). After 3 cell transfers, the metastatic lesion disappeared completely (c, d). (a, c):...
splits/sfolder_3/PMC4624843_pone.0141501.g002_438406.jpg
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Accumulation of (p)ppGpp in S8, S8ΔrelA and S8HB.Cells were labeled with [32P]-H3PO4-labelled in MOPS under starvation conditions, nucleotides were acid extracted, centrifuged, 32Pi-labeled nucleotides were resolved by polyethyleneimine coated TLC plates followed by autoradiography. (P)ppGpp separated by TLC are indica...
splits/subfolder_2/PMC4396151_Fig4_377902.jpg
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Activity-dependent mislocalisation of mutant PDGFRα. (A) 293FR-PDGFRα-GFP stable cell lines were treated with doxycycline for 14 h and subjected to confocal live cell microscopy. For figures d-f, the cells were additionally treated with 1 μM Gleevec for 14 h. (B) 293FR-PDGFRα stable cell lines were treated with doxyc...
splits/sfolder_2/PMC4662828_Fig1_448544.jpg
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Clinical diagnosis and surgical treatment. Preoperative sagittal magnetic resonance imaging (MRI) depicting the L5-S1 disc herniation immediately before surgery. The herniated disc can clearly be seen protruding into the spinal cord (a). Postoperative sagittal computed tomography (CT) scan immediately following surgery...
splits/subfolder_3/PMC3770586_pone-0074991-g004_231089.jpg
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Coronal CT and MRI slices of a CRS patient before and 166 days after sinus surgery.Superposition of the anterior gamma camera images with the CT slice before FESS (A–C) without (B) and with (C) central nasal lead shield mask and with the MRI slice after FESS (D–F) without (E) and with (F) lead shield. Lund-Mackay score...
splits/sfolder_1/PMC3764091_f3_229494.jpg
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Photomicrographs of H&E-stained tumors from BPA-treated rats at time of sacrifice at PND90 (A,D), 140 (B,E), and 200 (C,F) in gestationally and gestationally/lactationally exposed females. (A,B,D,E) Papillary adenocarcinoma from rats exposed gestationally to BPA250 (A) or BPA2.5 (D), or gestationallly/lactationally to ...
splits/subfolder_3/PMC2553280_pntd-0000311-g004_28107.jpg
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DV3 sE-eGFP protein is excluded from acidic compartments in MDdMφ.Confocal microscopic analysis of the localization of DV3 sE-eGFP protein at different time-points in cells loaded with the fluorescent LysoSensor dye (optimal fluorescence at pH 5.1). For the overlay images, blue color was converted to red to allow bette...