instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Five clones that hybridized weakly with the human retinoblastoma (Rb) gene were obtained by screening a human genomic library in a non-stringent condition.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for ... | <Mentions>: [retinoblastoma; rb]
<Options>: A: rb3 (homo sapiens) (aka stathmin 4)
B: rb1 (homo sapiens) (aka rb transcriptional corepressor 1)
C: rbb (homo sapiens) (aka nacc family member 2)
D: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
E... | [B; B] |
<Instruct>: Given the context 'The DNAs of two of these clones were partially sequenced and found to contain a region with considerable homology to part of the Rb gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, sepa... | <Mentions>: [rb]
<Options>: A: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
B: rbb (homo sapiens) (aka nacc family member 2)
C: prb (homo sapiens) (aka rb transcriptional corepressor 1)
D: rb-1 (homo sapiens) (aka rna binding motif protein 45)
E: rb3 (homo sapiens) (aka stathmin 4)
F: None of the abov... | [C] |
<Instruct>: Given the context 'As the L1 family is transposable, the Rb gene may be inactivated by recombination at this homologous region.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rb]
<Options>: A: rb3 (homo sapiens) (aka stathmin 4)
B: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
C: p105-rb (homo sapiens) (aka rb transcriptional corepressor 1)
D: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
E: rb (drosophila melanogaster) (retinoblastoma-family ... | [C] |
<Instruct>: Given the context 'As the L1 family is transposable, the Rb gene may be inactivated by recombination at this homologous region.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rb]
<Options>: A: rb3 (homo sapiens) (aka stathmin 4)
B: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
C: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
D: rbl1 (homo sapiens) (aka rb transcriptional corepressor li... | [E] |
<Instruct>: Given the context 'Another possibility related with the DNA binding properties of Rb and L1 family proteins is also discussed.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rb]
<Options>: A: rb3 (homo sapiens) (aka stathmin 4)
B: rb-1 (homo sapiens) (aka rna binding motif protein 45)
C: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
D: p105-rb (homo sapiens) (aka rb transcriptional corepressor 1)
E: r... | [D] |
<Instruct>: Given the context 'COUP transcription factor is a member of the steroid receptor superfamily.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [coup transcription factor]
<Options>: A: couptf1 (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
B: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
C: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 s homeolog (xenopus laevis)) (ak... | [A] |
<Instruct>: Given the context 'The COUP (chicken ovalbumin upstream promoter) transcription factor (COUP-TF) exists in a number of different tissues and is essential for expression of the chicken ovalbumin gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the s... | <Mentions>: [coup (chicken ovalbumin upstream promoter) transcription factor; coup-tf]
<Options>: A: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
B: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 s homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2,... | [F; F] |
<Instruct>: Given the context 'The COUP (chicken ovalbumin upstream promoter) transcription factor (COUP-TF) exists in a number of different tissues and is essential for expression of the chicken ovalbumin gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the s... | <Mentions>: [coup (chicken ovalbumin upstream promoter) transcription factor; coup-tf]
<Options>: A: coup-tf (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
B: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
C: coup-tfii (xenopus tropicalis) (aka nuclear receptor subfa... | [H; H] |
<Instruct>: Given the context 'COUP-TF also binds specifically to the rat insulin promoter element, although the two binding sites share little sequence similarity.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separate... | <Mentions>: [coup-tf]
<Options>: A: coup-tfii (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 2)
B: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
C: coup-tfi (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
D: coup-tfi (homo sapiens) (aka nuclear... | [D] |
<Instruct>: Given the context 'Here we report the isolation of a human complementary DNA clone encoding COUP-TF.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [coup-tf]
<Options>: A: couptfb (homo sapiens) (aka nuclear receptor subfamily 2 group f member 2)
B: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
C: coup-tfi (rattus norvegicus) (aka nuclear receptor subfamily 2, group f, member 1)
D: coup-tfa (xenopus tropicalis) (aka ... | [E] |
<Instruct>: Given the context 'Comparison of the amino-acid sequence of COUP-TF with known sequences reveals that it is a member of the steroid/thyroid hormone/vitamin receptor superfamily.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one f... | <Mentions>: [coup-tf]
<Options>: A: coup-tfii (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 2)
B: couptfb (homo sapiens) (aka nuclear receptor subfamily 2 group f member 2)
C: coup-tfi (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
D: coup-tfi (rattus norvegicus) (aka nuclear r... | [E] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
B: csf2 (homo sapiens) (aka colony stimulating factor 2)
C: interleukin 3 (homo sapiens) (aka interleukin 3)
D: il12rb (homo sapiens) (aka interleukin 12 rece... | [M; G; G; E] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
B: csf2 (homo sapiens) (aka colony stimulating factor 2)
C: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
D: il2 (homo sapiens) (aka i... | [I; D; D; N] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: interleukin 20 receptor subunit beta (homo sapiens) (aka interleukin 20 receptor subunit beta)
B: cd25 (homo sapiens) (interleukin 2 receptor subunit alpha (homo sapiens)) (aka interleukin 2 receptor subunit alpha)
C: inte... | [C; D; D; B] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: il22 (homo sapiens) (aka interleukin 22)
B: il-2 (homo sapiens) (aka interleukin 2)
C: interleukin 2 receptor subunit alpha (homo sapiens) (aka interleukin 2 receptor subunit alpha)
D: interleukin 3 (homo sapiens) (aka int... | [F; B; B; C] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: csf2rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
B: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka inte... | [N; N; C; C] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: interleukin 20 receptor subunit beta (homo sapiens) (aka interleukin 20 receptor subunit beta)
B: pp565 (homo sapiens) (aka pp565)
C: p-55 (homo sapiens) (aka peptidase, mitochondrial processing subunit alpha)
D: p55-gamma (homo sapiens) (aka ... | [P; P; M; M] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
B: pp565 (homo sapiens) (aka pp565)
C: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
D: il-2rg (homo sapiens) (aka interleukin 2 receptor sub... | [E; E; L; L] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: p55 (drosophila melanogaster) (regulatory particle non-atpase 5 (drosophila melanogaster)) (aka regulatory particle non-atpase 5)
B: interleukin 20 receptor subunit beta (homo sapiens) (aka interleukin 20 receptor subunit beta)
C: il2ra (homo ... | [C; C; N; N] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [p70-75]
<Options>: A: rpsap75 (homo sapiens) (aka ribosomal protein sa pseudogene 75)
B: pp75 (homo sapiens) (aka rab11 family interacting protein 5)
C: ppp1r75 (homo sapiens) (aka ferm, arh/rhogef and pleckstrin domain protein 1)
D: ck-75 (homo sapiens) (aka keratin 75)
E: p70-75 (homo sapiens) (aka inter... | [E] |
<Instruct>: Given the context 'The cDNA encoding the human IL-2R beta chain has now been isolated.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-2r beta]
<Options>: A: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
B: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: il2r (homo sapiens) (aka interleukin 2 receptor subunit alpha)
D: csf2rb (homo sapiens) (aka colony stimulating fac... | [B] |
<Instruct>: Given the context 'The overall primary structure of the IL-2R beta chain shows no apparent homology to other known receptors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-2r beta]
<Options>: A: colony stimulating factor 2 receptor subunit beta (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
B: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
C: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
D: il2rb (homo sapiens... | [D] |
<Instruct>: Given the context 'Unlike the IL-2R alpha chain, the IL-2R beta chain has a large cytoplasmic region in which a functional domain (or domains) mediating an intracellular signal transduction pathway (or pathways) may be embodied.', select the correct biomedical concept for each mention using the provided opt... | <Mentions>: [il-2r alpha; il-2r beta]
<Options>: A: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
B: il2rb (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: cd25 (homo sapiens) (interleukin 2 receptor subunit alpha (homo sapiens)) (aka interleukin 2 recepto... | [C; I] |
<Instruct>: Given the context 'Unlike the IL-2R alpha chain, the IL-2R beta chain has a large cytoplasmic region in which a functional domain (or domains) mediating an intracellular signal transduction pathway (or pathways) may be embodied.', select the correct biomedical concept for each mention using the provided opt... | <Mentions>: [il-2r alpha; il-2r beta]
<Options>: A: interleukin 2 receptor subunit alpha (homo sapiens) (aka interleukin 2 receptor subunit alpha)
B: il2r (homo sapiens) (aka interleukin 2 receptor subunit alpha)
C: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
D: il... | [A; H] |
<Instruct>: Given the context 'The cDNA-encoded beta chain binds and internalizes IL-2 when expressed on T lymphoid cells but not fibroblast cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-2]
<Options>: A: il2 (homo sapiens) (aka interleukin 2)
B: interleukin enhancer binding factor 2 (homo sapiens) (aka interleukin enhancer binding factor 2)
C: il22 (homo sapiens) (aka interleukin 22)
D: interleukin 3 (homo sapiens) (aka interleukin 3)
E: fgf-2 (homo sapiens) (aka fibroblast growth facto... | [A] |
<Instruct>: Given the context 'Furthermore, the cDNA gives rise to the generation of high-affinity IL-2 receptor when co-expressed with the IL-2R alpha chain cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated... | <Mentions>: [il-2 receptor; il-2r alpha]
<Options>: A: interleukin 2 receptor subunit gamma (homo sapiens) (aka interleukin 2 receptor subunit gamma)
B: colony stimulating factor 2 receptor subunit alpha (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
C: interleukin 2 receptor subunit beta (homo... | [C; I] |
<Instruct>: Given the context 'Furthermore, the cDNA gives rise to the generation of high-affinity IL-2 receptor when co-expressed with the IL-2R alpha chain cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated... | <Mentions>: [il-2 receptor; il-2r alpha]
<Options>: A: interleukin 1 receptor type 2 (homo sapiens) (aka interleukin 1 receptor type 2)
B: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
C: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
D: il2rb (ho... | [D; G] |
<Instruct>: Given the context 'Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ldl receptor]
<Options>: A: low density lipoprotein receptor (gallus gallus) (aka low density lipoprotein receptor)
B: very low density lipoprotein receptor (gallus gallus) (aka very low density lipoprotein receptor)
C: ldlr (homo sapiens) (aka low density lipoprotein receptor)
D: very low density lipoprot... | [C] |
<Instruct>: Given the context 'The pathogenesis of Heymann nephritis, a rat model of human membranous glomerulonephritis, depends on the interaction of autoantibodies with a renal glycoprotein (GP330) on glomerular podocytes.', select the correct biomedical concept for each mention using the provided options. Answer by... | <Mentions>: [gp330]
<Options>: A: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 s homeolog)
B: gp340 (homo sapiens) (aka deleted in malignant brain tumors 1)
C: gp330 (homo sapiens) (aka ldl receptor related protein 2)
D: gp280 (homo sa... | [C] |
<Instruct>: Given the context 'Partial complementary DNAs coding for GP330 were isolated and sequenced.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp330]
<Options>: A: gp330 (homo sapiens) (aka ldl receptor related protein 2)
B: gp330 (mus musculus) (aka low density lipoprotein receptor-related protein 2)
C: gp330 (xenopus tropicalis) (aka ldl receptor related protein 2)
D: gp280 (homo sapiens) (aka cubilin)
E: gp340 (xenopus tropicalis) (aka deleted... | [A] |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept for each mention using the prov... | <Mentions>: [low density lipoprotein (ldl) receptor; gp330; ldl receptor]
<Options>: A: gp280 (homo sapiens) (aka cubilin)
B: very low density lipoprotein receptor (gallus gallus) (aka very low density lipoprotein receptor)
C: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 l homeolog (xenopus laevis)) (aka... | [F; M; F] |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept for each mention using the prov... | <Mentions>: [low density lipoprotein (ldl) receptor; gp330; ldl receptor]
<Options>: A: gp330 (mus musculus) (aka low density lipoprotein receptor-related protein 2)
B: low density lipoprotein receptor (gallus gallus) (aka low density lipoprotein receptor)
C: ldlr (homo sapiens) (aka low density lipoprotein receptor)
D... | [C; L; C] |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept for each mention using the prov... | <Mentions>: [low density lipoprotein (ldl) receptor; gp330; ldl receptor]
<Options>: A: oxidized low density lipoprotein receptor 1 (homo sapiens) (aka oxidized low density lipoprotein receptor 1)
B: gp330 (xenopus tropicalis) (aka ldl receptor related protein 2)
C: ldlr (homo sapiens) (aka low density lipoprotein rece... | [C; D; C] |
<Instruct>: Given the context 'Autoantibodies from the kidneys of rats with Heymann nephritis reacted with a nonglycosylated segment of GP330 that contains cysteine-rich 40-amino acid repeats, which are also features of the LDL receptor.', select the correct biomedical concept for each mention using the provided option... | <Mentions>: [gp330; ldl receptor]
<Options>: A: gp330 (xenopus laevis) (aka ldl receptor related protein 2 l homeolog)
B: very low density lipoprotein receptor (homo sapiens) (aka very low density lipoprotein receptor)
C: low density lipoprotein receptor (homo sapiens) (aka low density lipoprotein receptor)
D: gp280 (h... | [F; C] |
<Instruct>: Given the context 'Autoantibodies from the kidneys of rats with Heymann nephritis reacted with a nonglycosylated segment of GP330 that contains cysteine-rich 40-amino acid repeats, which are also features of the LDL receptor.', select the correct biomedical concept for each mention using the provided option... | <Mentions>: [gp330; ldl receptor]
<Options>: A: gp340 (homo sapiens) (aka deleted in malignant brain tumors 1)
B: ldlr (homo sapiens) (aka low density lipoprotein receptor)
C: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 l homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 l homeolog)
D:... | [E; B] |
<Instruct>: Given the context 'GP330 is also similar in some regions to the mouse epidermal growth factor precursor.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp330]
<Options>: A: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 l homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 l homeolog)
B: gp330 (homo sapiens) (aka ldl receptor related protein 2)
C: gp43 (xenopus laevis) (provisional ortholog of zona pellucida glycoprotein 3 s h... | [B] |
<Instruct>: Given the context 'GP330 is also similar in some regions to the mouse epidermal growth factor precursor.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp330]
<Options>: A: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 s homeolog)
B: gp43 (xenopus laevis) (provisional ortholog of zona pellucida glycoprotein 3 s homeolog (xenopus laevis)) (aka provisional ortholog of zona p... | [E] |
<Instruct>: Given the context 'Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrna polyadenylate binding protein]
<Options>: A: polyadenylate-binding protein 2-binding protein (arabidopsis thaliana) (aka polyadenylate-binding protein 2-binding protein)
B: poly(a) binding protein (drosophila melanogaster) (aka poly(a) binding protein)
C: polyadenylate-binding protein 5-like (glycine ... | [E] |
<Instruct>: Given the context 'We have isolated a full length cDNA (cDNA) coding for the human poly(A) binding protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [poly(a) binding protein]
<Options>: A: poly(a) binding protein nuclear 1 (homo sapiens) (aka poly(a) binding protein nuclear 1)
B: poly(a) binding protein 1 (arabidopsis thaliana) (aka poly(a) binding protein 1)
C: poly(a) binding protein (drosophila melanogaster) (aka poly(a) binding protein)
D: poly(a)-b... | [E] |
<Instruct>: Given the context 'The cDNA derived 73 kd basic translation product has the same Mr, isoelectric point and peptidic map as the poly(A) binding protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated... | <Mentions>: [poly(a) binding protein]
<Options>: A: poly(a) binding protein 1 (arabidopsis thaliana) (aka poly(a) binding protein 1)
B: poly(a) binding protein, cytoplasmic 1 (xenopus tropicalis) (aka poly(a) binding protein, cytoplasmic 1)
C: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-bi... | [D] |
<Instruct>: Given the context 'The N terminal part, highly homologous to the yeast poly(A) binding protein, is sufficient for poly(A) binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolo... | <Mentions>: [poly(a) binding protein]
<Options>: A: pabp (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
B: poly(a) binding protein 1 (arabidopsis thaliana) (aka poly(a) binding protein 1)
C: poly(a) binding protein (drosophila melanogaster) (aka poly(a) binding protein)
D: poly(a) binding protein nuclear 1 ... | [A] |
<Instruct>: Given the context 'Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c1; c8]
<Options>: A: hho.c1 (homo sapiens) (aka homeobox b7)
B: g8 (homo sapiens) (aka small nucleolar rna host gene 32)
C: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
D: c1in (homo sapiens) (aka serpin family g member 1)
E: hho.c8 (homo sapiens) (aka homeobox c6)
F: homeobox c8 (homo... | [A; F] |
<Instruct>: Given the context 'Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c1; c8]
<Options>: A: m8 (homo sapiens) (aka prion locus lncrna, testis expressed)
B: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
C: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
D: homeobox c8 (homo sapiens) (aka homeobox c8)
E: c1_c (ho... | [J; D] |
<Instruct>: Given the context 'Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opti... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: ch1 (homo sapiens) (aka sun domain containing ossification factor)
B: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
C: coh1 (homo sapiens) (aka vacuolar protein sorting 13 homolog b)
D: hho.c1 (homo sapiens) (aka homeobox b7)
E: ... | [D; F] |
<Instruct>: Given the context 'Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opti... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: coh1 (homo sapiens) (aka vacuolar protein sorting 13 homolog b)
B: o8 (homo sapiens) (aka immunoglobulin kappa variable 1d-33)
C: hox8 (homo sapiens) (aka msh homeobox 2)
D: hho.c1 (homo sapiens) (aka homeobox b7)
E: one cut homeobox 1 (homo sapiens) (aka one cut homeobox 1)
F... | [D; J] |
<Instruct>: Given the context 'Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opti... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
B: hoxc8 (homo sapiens) (aka homeobox c8)
C: coh1 (homo sapiens) (aka vacuolar protein sorting 13 homolog b)
D: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
E: hh8 ... | [I; B] |
<Instruct>: Given the context 'Expression of the corresponding genes, termed c1 and c8, was evaluated in different organs and body parts during human embryonic/fetal development.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each men... | <Mentions>: [c1; c8]
<Options>: A: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
B: homeobox c8 (homo sapiens) (aka homeobox c8)
C: c1_c (homo sapiens) (aka endogenous retrovirus group k member 18)
D: scg8 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
E: hho.c1 (homo sap... | [E; B] |
<Instruct>: Given the context 'Expression of the corresponding genes, termed c1 and c8, was evaluated in different organs and body parts during human embryonic/fetal development.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each men... | <Mentions>: [c1; c8]
<Options>: A: c1s (homo sapiens) (aka complement c1s)
B: c8g (homo sapiens) (aka complement c8 gamma chain)
C: homeobox c8 (homo sapiens) (aka homeobox c8)
D: complement c1r (homo sapiens) (aka complement c1r)
E: scg8 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
F: h... | [I; C] |
<Instruct>: Given the context 'HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111', select the correct biomedical concept for each mention using the provided options... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: hho.c1 (homo sapiens) (aka homeobox b7)
B: ch1 (homo sapiens) (aka sun domain containing ossification factor)
C: atoh8 (homo sapiens) (aka atonal bhlh transcription factor 8)
D: hho.c8 (homo sapiens) (aka homeobox c6)
E: hho.c1 (xenopus tropicalis) (aka homeobox b7)
F: hoxc8 (... | [A; F] |
<Instruct>: Given the context 'HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111', select the correct biomedical concept for each mention using the provided options... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: hoxc8 (homo sapiens) (aka homeobox c8)
B: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
C: hox8 (homo sapiens) (aka msh homeobox 2)
D: hh8 (homo sapiens) (aka kiss1 receptor)
E: a-c1 (homo sapiens) (aka phospholipase a and acyltr... | [I; A] |
<Instruct>: Given the context 'HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111', select the correct biomedical concept for each mention using the provided options... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: hox8 (homo sapiens) (aka msh homeobox 2)
B: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
C: coh1 (homo sapiens) (aka vacuolar protein sorting 13 homolog b)
D: hoxc8 (homo sapiens) (aka homeobox c8)
E: hhc1 (homo sapiens) (aka calcium sensing receptor)
F: hh8... | [J; D] |
<Instruct>: Given the context 'encodes a 153-amino acid protein containing a homeodomain identical to that of the frog AC1 gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ac1]
<Options>: A: acyp1 (homo sapiens) (aka acylphosphatase 1)
B: an1 (homo sapiens) (aka paired box 6)
C: aconitase 1 (homo sapiens) (aka aconitase 1)
D: acetyl-coa acetyltransferase 1 (homo sapiens) (aka acetyl-coa acetyltransferase 1)
E: ach1 (homo sapiens) (aka acyl-coa thioesterase 7)
F: None of the ... | [F] |
<Instruct>: Given the context 'Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hho.c1; hho.c8]
<Options>: A: c8c (homo sapiens) (aka complement c8 gamma chain)
B: hypoc1 (homo sapiens) (aka calcium sensing receptor)
C: hh8 (homo sapiens) (aka kiss1 receptor)
D: coh1 (homo sapiens) (aka vacuolar protein sorting 13 homolog b)
E: hoxc8 (homo sapiens) (aka homeobox c8)
F: hc1 (homo sapie... | [H; E] |
<Instruct>: Given the context 'Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hho.c1; hho.c8]
<Options>: A: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
B: hc1 (homo sapiens) (aka cycs pseudogene 39)
C: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
D: hox8 (homo sapiens) (aka msh homeobox 2)
E: hha8 (homo sapiens) (a... | [H; J] |
<Instruct>: Given the context 'These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes.',... | <Mentions>: [c1; c8]
<Options>: A: c8c (homo sapiens) (aka complement c8 gamma chain)
B: c1_c (homo sapiens) (aka endogenous retrovirus group k member 18)
C: host cell factor c1 (bos taurus) (aka host cell factor c1)
D: c1r (homo sapiens) (aka complement c1r)
E: hho.c1 (homo sapiens) (aka homeobox b7)
F: g8 (homo sapie... | [E; I] |
<Instruct>: Given the context 'These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes.',... | <Mentions>: [c1; c8]
<Options>: A: c1s (homo sapiens) (aka complement c1s)
B: scg8 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
C: c8g (homo sapiens) (aka complement c8 gamma chain)
D: homeobox c8 (homo sapiens) (aka homeobox c8)
E: complement c1r (homo sapiens) (aka complement c1r)
F: h... | [G; D] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: homeobox c10 (homo sapiens) (aka homeobox c10)
B: ck13 (homo sapiens) (aka keratin 13)
C: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
D: c10 (mus musculus) (gene rich cluster, c10 gene (mus musculus)) (aka gene rich cluster, ... | [J; E; A; S] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
B: carbonic anhydrase 13 (homo sapiens) (aka carbonic anhydrase 13)
C: c8a (homo sapiens) (aka complement c8 alpha chain)
D: c10 (homo sapiens) (aka chromosome 12 open reading frame... | [S; Q; H; E] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: small cysteine and glycine repeat containing 10 (gene/pseudogene) (homo sapiens) (aka small cysteine and glycine repeat containing 10 (gene/pseudogene))
B: hc10 (homo sapiens) (aka cycs pseudogene 25)
C: ck13 (homo sapiens) (aka keratin 13)
D: o13 (homo sapiens) (aka immunog... | [L; G; O; R] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: hc10 (homo sapiens) (aka cycs pseudogene 25)
B: c1s (homo sapiens) (aka complement c1s)
C: hho.c1 (homo sapiens) (aka homeobox b7)
D: homeobox c13 (homo sapiens) (aka homeobox c13)
E: il13 (homo sapiens) (aka interleukin 13)
F: m8 (drosophila melanogaster) (enhancer of split... | [C; M; N; D] |
<Instruct>: Given the context 'Studies of the human c-myb gene and its product in human acute leukemias.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb]
<Options>: A: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
B: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
C: c-myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
D: mybp-c (homo sapiens) (aka myosin binding protein c3)
E: c-myb (mus musculus) (aka myeloblastosis ... | [C] |
<Instruct>: Given the context 'The myb gene is the transforming oncogene of the avian myeloblastosis virus (AMV); its normal cellular homolog, c-myb, is conserved across a broad span of evolution.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options... | <Mentions>: [myb; c-myb]
<Options>: A: myb proto-oncogene like 1 (homo sapiens) (aka myb proto-oncogene like 1)
B: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
C: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
D: mybp-c (homo sapiens) (aka myosin binding protein c3)
E: myb (homo sapiens) (aka myb pro... | [E; E] |
<Instruct>: Given the context 'The myb gene is the transforming oncogene of the avian myeloblastosis virus (AMV); its normal cellular homolog, c-myb, is conserved across a broad span of evolution.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options... | <Mentions>: [myb; c-myb]
<Options>: A: myb (mus musculus) (aka myeloblastosis oncogene)
B: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
C: myb (drosophila melanogaster) (aka myb oncogene-like)
D: mybp-c (homo sapiens) (aka myosin binding protein c3)
E: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
F: c-m... | [I; I] |
<Instruct>: Given the context 'The myb gene is the transforming oncogene of the avian myeloblastosis virus (AMV); its normal cellular homolog, c-myb, is conserved across a broad span of evolution.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options... | <Mentions>: [myb; c-myb]
<Options>: A: v-myb avian myeloblastosis viral oncogene homolog (danio rerio) (aka v-myb avian myeloblastosis viral oncogene homolog)
B: myb (drosophila melanogaster) (aka myb oncogene-like)
C: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
D: b-myb (mus musculus) (aka myeloblastosis onco... | [I; I] |
<Instruct>: Given the context 'In humans, c-myb is expressed in malignant hematopoietic cell lines and in primary hematopoietic tumors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb]
<Options>: A: mybp-c (homo sapiens) (aka myosin binding protein c3)
B: c-myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
C: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
D: c-myb (mus musculus) (aka myeloblastosis oncogene)
E: b-myb (mus musculus) (aka myeloblastosis oncogen... | [B] |
<Instruct>: Given the context 'The sequences of the clones were compared to the c-myb of other species, as well as the v-myb of AMV.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb; v-myb]
<Options>: A: myb proto-oncogene, transcription factor (gallus gallus) (aka myb proto-oncogene, transcription factor)
B: mybp-c (homo sapiens) (aka myosin binding protein c3)
C: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
D: myb (mus musculus) (aka myeloblastosis oncogene)
E: my... | [E; E] |
<Instruct>: Given the context 'The sequences of the clones were compared to the c-myb of other species, as well as the v-myb of AMV.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb; v-myb]
<Options>: A: v-myb avian myeloblastosis viral oncogene homolog (danio rerio) (aka v-myb avian myeloblastosis viral oncogene homolog)
B: c-myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
C: mybp-c (homo sapiens) (aka myosin binding protein c3)
D: b-myb (homo sapiens) (aka my... | [B; B] |
<Instruct>: Given the context 'In addition, the carboxyl terminal region of human c-myb was placed in an expression vector to obtain protein for the generation of antiserum, which was used to identify the human c-myb gene product.', select the correct biomedical concept for each mention using the provided options. Answ... | <Mentions>: [c-myb]
<Options>: A: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
B: mybp-c (homo sapiens) (aka myosin binding protein c3)
C: c-myb (mus musculus) (aka myeloblastosis oncogene)
D: c-myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
E: b-myb (mus musculus) (aka myeloblastosis oncogen... | [D] |
<Instruct>: Given the context 'Like v-myb, this protein was found within the nucleus of leukemic cells where it was associated with the nuclear matrix.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolo... | <Mentions>: [v-myb]
<Options>: A: myb proto-oncogene, transcription factor (homo sapiens) (aka myb proto-oncogene, transcription factor)
B: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
C: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
D: v-myb avian myeloblastosis viral oncogene homolog (danio rerio) (aka... | [A] |
<Instruct>: Given the context 'These studies provide further evidence that c-myb might be involved in human leukemia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb]
<Options>: A: mybp-c (homo sapiens) (aka myosin binding protein c3)
B: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
C: myb proto-oncogene, transcription factor (homo sapiens) (aka myb proto-oncogene, transcription factor)
D: myb proto-oncogene like 1 (homo sapiens) (aka myb proto-oncogene li... | [C] |
<Instruct>: Given the context 'Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number.
cDNA clones for human B creatine kinase were isolated from human brain and placenta libraries.', select the correct biomed... | <Mentions>: [b creatine kinase]
<Options>: A: ckb (mus musculus) (creatine kinase, brain (mus musculus)) (aka creatine kinase, brain)
B: creatine kinase b (rattus norvegicus) (aka creatine kinase b)
C: ckb (homo sapiens) (creatine kinase b (homo sapiens)) (aka creatine kinase b)
D: creatine kinase, brain b (danio rerio... | [C] |
<Instruct>: Given the context 'A 77.7% nucleotide sequence identity was found between the coding region of human B creatine kinase and our previously reported human M creatine kinase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [b creatine kinase; m creatine kinase]
<Options>: A: ckb (mus musculus) (creatine kinase, brain (mus musculus)) (aka creatine kinase, brain)
B: creatine kinase, muscle b (danio rerio) (aka creatine kinase, muscle b)
C: ckb (bos taurus) (aka creatine kinase b)
D: creatine kinase b (sus scrofa) (aka creatine ... | [F; H] |
<Instruct>: Given the context 'A 77.7% nucleotide sequence identity was found between the coding region of human B creatine kinase and our previously reported human M creatine kinase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [b creatine kinase; m creatine kinase]
<Options>: A: creatine kinase, brain b (danio rerio) (aka creatine kinase, brain b)
B: creatine kinase, m-type (homo sapiens) (aka creatine kinase, m-type)
C: creatine kinase, mitochondrial 1, ubiquitous (mus musculus) (aka creatine kinase, mitochondrial 1, ubiquitous)... | [H; B] |
<Instruct>: Given the context 'Southern transfers of total genomic DNA derived from human placenta and digested to completion with several restriction enzymes were probed with the MCK and BCK specific probes producing single hybridization bands.', select the correct biomedical concept for each mention using the provide... | <Mentions>: [mck; bck]
<Options>: A: mcak (mus musculus) (aka kinesin family member 2c)
B: blk (homo sapiens) (aka blk proto-oncogene, src family tyrosine kinase)
C: blk proto-oncogene, src family tyrosine kinase (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
D: prkcb (bos taurus) (aka protein kinase... | [K; E] |
<Instruct>: Given the context 'Southern transfers of total genomic DNA derived from human placenta and digested to completion with several restriction enzymes were probed with the MCK and BCK specific probes producing single hybridization bands.', select the correct biomedical concept for each mention using the provide... | <Mentions>: [mck; bck]
<Options>: A: bckb (homo sapiens) (aka creatine kinase b)
B: csk (bos taurus) (aka c-terminal src kinase)
C: cpk-mm (mus musculus) (aka creatine kinase, muscle)
D: serine/threonine/tyrosine protein kinase mck1 (saccharomyces cerevisiae s288c) (aka serine/threonine/tyrosine protein kinase mck1)
E:... | [K; A] |
<Instruct>: Given the context 'Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [dna polymerase delta]
<Options>: A: cdc2 (homo sapiens) (dna polymerase delta 1, catalytic subunit (homo sapiens)) (aka dna polymerase delta 1, catalytic subunit)
B: dna polymerase delta 3, accessory subunit (homo sapiens) (aka dna polymerase delta 3, accessory subunit)
C: dna polymerase delta 2, accessory... | [A] |
<Instruct>: Given the context 'Previous studies have specifically implicated DNA polymerase delta as the enzyme involved in DNA repair synthesis occurring immediately after UV damage.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [dna polymerase delta]
<Options>: A: dna polymerase lambda (homo sapiens) (aka dna polymerase lambda)
B: dna polymerase delta catalytic subunit (caenorhabditis elegans) (aka dna polymerase delta catalytic subunit)
C: dna polymerase delta 1, catalytic subunit (homo sapiens) (aka dna polymerase delta 1, catal... | [C] |
<Instruct>: Given the context 'In permeable cells, the process was further analyzed by using the nucleotide analogue (butylphenyl)-2'-deoxyguanosine 5'-triphosphate, which inhibits DNA polymerase alpha several hundred times more strongly than it inhibits DNA polymerase delta.', select the correct biomedical concept for... | <Mentions>: [dna polymerase alpha; dna polymerase delta]
<Options>: A: dna polymerase theta (homo sapiens) (aka dna polymerase theta)
B: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
C: dna-directed dna polymerase alpha catalytic subunit pol1 (saccharomyces cer... | [G; E] |
<Instruct>: Given the context 'In permeable cells, the process was further analyzed by using the nucleotide analogue (butylphenyl)-2'-deoxyguanosine 5'-triphosphate, which inhibits DNA polymerase alpha several hundred times more strongly than it inhibits DNA polymerase delta.', select the correct biomedical concept for... | <Mentions>: [dna polymerase alpha; dna polymerase delta]
<Options>: A: dna polymerase iota (homo sapiens) (aka dna polymerase iota)
B: dna polymerase catalytic subunit (human alphaherpesvirus 1) (aka dna polymerase catalytic subunit)
C: dna polymerase alpha 1, catalytic subunit (homo sapiens) (aka dna polymerase alpha ... | [C; F] |
<Instruct>: Given the context 'The (butylphenyl)-2'-deoxyguanosine 5'-triphosphate inhibition curve for late UV-induced repair synthesis was very similar to that for polymerase delta.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [polymerase delta]
<Options>: A: pold (homo sapiens) (aka dna polymerase delta 1, catalytic subunit)
B: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
C: dna polymerase lambda (homo sapiens) (aka dna polymerase lambda)
D: dna polymerase delta 3, acce... | [A] |
<Instruct>: Given the context 'It appears that repair synthesis at late times after UV irradiation, like repair synthesis at early times, is mediated by DNA polymerase delta.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention... | <Mentions>: [dna polymerase delta]
<Options>: A: dna polymerase delta 3, accessory subunit (homo sapiens) (aka dna polymerase delta 3, accessory subunit)
B: dna polymerase iota (homo sapiens) (aka dna polymerase iota)
C: dna polymerase theta (homo sapiens) (aka dna polymerase theta)
D: cdc2 (homo sapiens) (dna polymera... | [D] |
<Instruct>: Given the context 'Molecular cloning and primary structure of human 15-lipoxygenase.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [15-lipoxygenase]
<Options>: A: arachidonate 15-lipoxygenase (oryctolagus cuniculus) (aka arachidonate 15-lipoxygenase)
B: 15-lox (homo sapiens) (aka arachidonate 15-lipoxygenase)
C: arachidonate 15-lipoxygenase (rattus norvegicus) (aka arachidonate 15-lipoxygenase)
D: 15-lox-2 (homo sapiens) (aka arachidon... | [B] |
<Instruct>: Given the context 'A full-length cDNA encoding 15-lipoxygenase has been isolated from a human reticulocyte cDNA library.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [15-lipoxygenase]
<Options>: A: arachidonate 15-lipoxygenase (oryctolagus cuniculus) (aka arachidonate 15-lipoxygenase)
B: arachidonate 15-lipoxygenase type b (homo sapiens) (aka arachidonate 15-lipoxygenase type b)
C: arachidonate 5-lipoxygenase (homo sapiens) (aka arachidonate 5-lipoxygenase)
D: 12-lox (h... | [D] |
<Instruct>: Given the context 'The predicted primary structure of the enzyme exhibits a sequence similarity of 61% and 45% with human 5-lipoxygenase and the soybean lipoxygenase isoenzyme I, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [5-lipoxygenase; lipoxygenase isoenzyme i]
<Options>: A: arachidonate 5-lipoxygenase (gallus gallus) (aka arachidonate 5-lipoxygenase)
B: arachidonate 5-lipoxygenase (rattus norvegicus) (aka arachidonate 5-lipoxygenase)
C: 15-lox-1 (homo sapiens) (aka arachidonate 15-lipoxygenase)
D: lox (homo sapiens) (aka... | [F; J] |
<Instruct>: Given the context 'The predicted primary structure of the enzyme exhibits a sequence similarity of 61% and 45% with human 5-lipoxygenase and the soybean lipoxygenase isoenzyme I, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [5-lipoxygenase; lipoxygenase isoenzyme i]
<Options>: A: lox (homo sapiens) (aka lysyl oxidase)
B: arachidonate 5-lipoxygenase (homo sapiens) (aka arachidonate 5-lipoxygenase)
C: loxl1 (homo sapiens) (aka lysyl oxidase like 1)
D: arachidonate 5-lipoxygenase (rattus norvegicus) (aka arachidonate 5-lipoxygena... | [B; J] |
<Instruct>: Given the context 'Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by sem... | <Mentions>: [srf; c-fos]
<Options>: A: c-fos (xenopus laevis) (fbj murine osteosarcoma viral oncogene homolog s homeolog (xenopus laevis)) (aka fbj murine osteosarcoma viral oncogene homolog s homeolog)
B: fos proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka fos proto-oncogene, ap-1 transcription f... | [F; B] |
<Instruct>: Given the context 'Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by sem... | <Mentions>: [srf; c-fos]
<Options>: A: srf (homo sapiens) (aka serum response factor)
B: serum response factor homolog b (glycine max) (aka serum response factor homolog b)
C: srf-1 (homo sapiens) (aka spermatogenesis associated 6)
D: fos (homo sapiens) (aka fos proto-oncogene, ap-1 transcription factor subunit)
E: srf... | [A; D] |
<Instruct>: Given the context 'We have isolated cDNA clones encoding serum response factor (SRF), a ubiquitous nuclear protein that binds to the SRE.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [serum response factor; srf]
<Options>: A: srf (mus musculus) (aka serum response factor)
B: srf (sus scrofa) (aka serum response factor)
C: serum response factor homolog b (glycine max) (aka serum response factor homolog b)
D: serum response factor binding protein 1 (homo sapiens) (aka serum response facto... | [I; I] |
<Instruct>: Given the context 'We have isolated cDNA clones encoding serum response factor (SRF), a ubiquitous nuclear protein that binds to the SRE.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [serum response factor; srf]
<Options>: A: srf (sus scrofa) (aka serum response factor)
B: srf (mus musculus) (aka serum response factor)
C: serum response factor (gallus gallus) (aka serum response factor)
D: srf1 (homo sapiens) (aka spermatogenesis associated 6)
E: serum response factor (bos taurus) (aka ... | [H; H] |
<Instruct>: Given the context 'The SRF gene is highly conserved through evolution, and in cultured cells its transcription is itself transiently increased following serum stimulation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [srf]
<Options>: A: serum response factor homolog b (glycine max) (aka serum response factor homolog b)
B: srf-1 (homo sapiens) (aka spermatogenesis associated 6)
C: serum response factor (sus scrofa) (aka serum response factor)
D: srf (homo sapiens) (aka serum response factor)
E: serum response factor (xen... | [D] |
<Instruct>: Given the context 'The SRF gene is highly conserved through evolution, and in cultured cells its transcription is itself transiently increased following serum stimulation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [srf]
<Options>: A: srf-1 (homo sapiens) (aka spermatogenesis associated 6)
B: serum response factor (sus scrofa) (aka serum response factor)
C: serum response factor homolog b (glycine max) (aka serum response factor homolog b)
D: serum response factor (xenopus tropicalis) (aka serum response factor)
E: No... | [E] |
<Instruct>: Given the context 'A cDNA clone of SRF expressed in vitro generates protein that forms complexes indistinguishable from those formed with HeLa cell SRF, as judged by DNA binding specificity and the ability to promote SRE-dependent in vitro transcription.', select the correct biomedical concept for each ment... | <Mentions>: [srf]
<Options>: A: serum response factor (xenopus tropicalis) (aka serum response factor)
B: serum response factor (homo sapiens) (aka serum response factor)
C: serum response factor homolog b (glycine max) (aka serum response factor homolog b)
D: srf (sus scrofa) (aka serum response factor)
E: srf-1 (homo... | [B] |
<Instruct>: Given the context 'SRF binds DNA as a dimer, and the DNA binding/dimerization domain of the protein exhibits striking homology to two yeast regulatory proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, ... | <Mentions>: [srf]
<Options>: A: serum response factor (sus scrofa) (aka serum response factor)
B: srf (homo sapiens) (aka serum response factor)
C: serum response factor homolog b (glycine max) (aka serum response factor homolog b)
D: srf1 (homo sapiens) (aka spermatogenesis associated 6)
E: serum response factor homol... | [B] |
<Instruct>: Given the context 'Isolation of cDNA clones coding for rat isovaleryl-CoA dehydrogenase and assignment of the gene to human chromosome 15.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolo... | <Mentions>: [isovaleryl-coa dehydrogenase]
<Options>: A: isovaleryl-coa dehydrogenase (xenopus tropicalis) (aka isovaleryl-coa dehydrogenase)
B: isovaleryl-coa dehydrogenase (bos taurus) (aka isovaleryl-coa dehydrogenase)
C: isovaleryl-coa dehydrogenase (sus scrofa) (aka isovaleryl-coa dehydrogenase)
D: isovaleryl-coa ... | [D] |
<Instruct>: Given the context 'Rat liver mRNA encoding the cytoplasmic precursor of mitochondrial isovaleryl-CoA dehydrogenase was highly enriched by polysome immunopurification using a polyclonal monospecific antibody.', select the correct biomedical concept for each mention using the provided options. Answer by listi... | <Mentions>: [isovaleryl-coa dehydrogenase]
<Options>: A: isovaleryl-coa dehydrogenase (rattus norvegicus) (aka isovaleryl-coa dehydrogenase)
B: isovaleryl-coa dehydrogenase (sus scrofa) (aka isovaleryl-coa dehydrogenase)
C: isovaleryl-coa dehydrogenase (oryctolagus cuniculus) (aka isovaleryl-coa dehydrogenase)
D: isova... | [A] |
<Instruct>: Given the context 'The purified mRNA was used to prepare a plasmid cDNA library which was screened with two oligonucleotide mixtures encoding two peptides in the amino-terminal portion of mature rat isovaleryl-CoA dehydrogenase.', select the correct biomedical concept for each mention using the provided opt... | <Mentions>: [isovaleryl-coa dehydrogenase]
<Options>: A: isovaleryl-coa dehydrogenase (rattus norvegicus) (aka isovaleryl-coa dehydrogenase)
B: isovaleryl-coa dehydrogenase (oryctolagus cuniculus) (aka isovaleryl-coa dehydrogenase)
C: isovaleryl-coa dehydrogenase (danio rerio) (aka isovaleryl-coa dehydrogenase)
D: isov... | [A] |
<Instruct>: Given the context 'Southern blot analysis of DNAs from human-rodent somatic cell hybrids with an isolated rat cDNA (2 kbp) assigned the isovaleryl-CoA dehydrogenase gene to the long arm of chromosome 15, region q14----qter.', select the correct biomedical concept for each mention using the provided options.... | <Mentions>: [isovaleryl-coa dehydrogenase]
<Options>: A: isovaleryl-coa dehydrogenase (xenopus tropicalis) (aka isovaleryl-coa dehydrogenase)
B: isovaleryl-coa dehydrogenase (bos taurus) (aka isovaleryl-coa dehydrogenase)
C: isovaleryl-coa dehydrogenase (rattus norvegicus) (aka isovaleryl-coa dehydrogenase)
D: isovaler... | [C] |
<Instruct>: Given the context 'This location differs from that of the gene for medium-chain acyl-CoA dehydrogenase, a closely related enzyme, which has been previously assigned to chromosome 1.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, o... | <Mentions>: [medium-chain acyl-coa dehydrogenase]
<Options>: A: acyl-coa dehydrogenase medium chain (sus scrofa) (aka acyl-coa dehydrogenase medium chain)
B: medium-chain specific acyl-coa dehydrogenase, mitochondrial (caenorhabditis elegans) (aka medium-chain specific acyl-coa dehydrogenase, mitochondrial)
C: acyl-coa... | [C] |
<Instruct>: Given the context 'Molecular cloning of a cDNA for human delta-aminolevulinate dehydratase.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [delta-aminolevulinate dehydratase]
<Options>: A: aminolevulinate dehydratase (sus scrofa) (aka aminolevulinate dehydratase)
B: aminolevulinate, delta-, dehydratase (glycine max) (aka aminolevulinate, delta-, dehydratase)
C: aminolevulinate dehydratase (oryctolagus cuniculus) (aka aminolevulinate dehydratas... | [E] |
<Instruct>: Given the context 'A cDNA encoding human delta-aminolevulinic acid dehydratase (ALA-D; EC 4.2.1.24), the second enzyme in the heme biosynthetic pathway, was isolated from a human liver cDNA expression library.', select the correct biomedical concept for each mention using the provided options. Answer by lis... | <Mentions>: [delta-aminolevulinic acid dehydratase; ala-d]
<Options>: A: alad (xenopus laevis) (aka aminolevulinate dehydratase l homeolog)
B: aminolevulinate dehydratase s homeolog (xenopus laevis) (aka aminolevulinate dehydratase s homeolog)
C: aminolevulinate dehydratase (homo sapiens) (aka aminolevulinate dehydrata... | [C; C] |
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