instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'A screen of human tissues with this antibody reveals retinoschisin to be retina specific and the antibody detects a protein of similar size in bovine and murine retinae.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opt... | <Mentions>: [retinoschisin]
<Options>: A: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
B: retinoschisin 1 (xenopus tropicalis) (aka retinoschisin 1)
C: retinoschisin 1 (gallus gallus) (aka retinoschisin 1)
D: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
E: retinoschisin 1 (homo sap... | [E] |
<Instruct>: Given the context 'We investigated the expression pattern in the retina of both RS1 mRNA (using in situ hybridization with riboprobes) and retinoschisin (using immunohistochemistry).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, ... | <Mentions>: [rs1; retinoschisin]
<Options>: A: rsg1 (homo sapiens) (aka ciliogenesis and planar polarity effector complex subunit 2)
B: retinoschisin 1a (danio rerio) (aka retinoschisin 1a)
C: rsts1 (homo sapiens) (aka creb binding lysine acetyltransferase)
D: rsrc1 (homo sapiens) (aka arginine and serine rich coiled-c... | [H; H] |
<Instruct>: Given the context 'We investigated the expression pattern in the retina of both RS1 mRNA (using in situ hybridization with riboprobes) and retinoschisin (using immunohistochemistry).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, ... | <Mentions>: [rs1; retinoschisin]
<Options>: A: rsrp1 (homo sapiens) (aka arginine and serine rich protein 1)
B: retinoschisin 1 (gallus gallus) (aka retinoschisin 1)
C: retinoschisin 1 (sus scrofa) (aka retinoschisin 1)
D: rsrc1 (homo sapiens) (aka arginine and serine rich coiled-coil 1)
E: retinoschisin 1a (danio reri... | [G; G] |
<Instruct>: Given the context 'The antisense riboprobe detected RS1 mRNA only in the photoreceptor layer but the protein product of the gene was present both in the photoreceptors and within the inner portions of the retina.', select the correct biomedical concept for each mention using the provided options. Answer by ... | <Mentions>: [rs1]
<Options>: A: rs1 (human alphaherpesvirus 1) (transcriptional regulator icp4 (human alphaherpesvirus 1)) (aka transcriptional regulator icp4)
B: rsf1 (homo sapiens) (aka remodeling and spacing factor 1)
C: rs (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
D: rsg1 (homo sapiens) ... | [C] |
<Instruct>: Given the context 'Furthermore, differentiated retinoblastoma cells (Weri-Rb1 cells) were found to express RS1 mRNA and to release retinoschisin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [rs1; retinoschisin]
<Options>: A: retinoschisin 1a (danio rerio) (aka retinoschisin 1a)
B: rs (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
C: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
D: rsts1 (homo sapiens) (aka creb binding lysine acetyltransfer... | [B; B] |
<Instruct>: Given the context 'Furthermore, differentiated retinoblastoma cells (Weri-Rb1 cells) were found to express RS1 mRNA and to release retinoschisin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [rs1; retinoschisin]
<Options>: A: rs1 (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
B: retinoschisin 1 (sus scrofa) (aka retinoschisin 1)
C: rsg1 (homo sapiens) (aka ciliogenesis and planar polarity effector complex subunit 2)
D: retinoschisin 1 (xenopus tropicalis) (aka retinoschis... | [A; A] |
<Instruct>: Given the context 'These results suggest that retinoschisin is released by photo-receptors and has functions within the inner retinal layers.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semico... | <Mentions>: [retinoschisin]
<Options>: A: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
B: retinoschisin 1 (rattus norvegicus) (aka retinoschisin 1)
C: rs1 (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
D: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
E: retino... | [C] |
<Instruct>: Given the context 'Thus, X-linked retinoschisis is caused by abnormalities in a putative secreted photoreceptor protein and is the first example of a secreted photo-receptor protein associated with a retinal dystrophy.', select the correct biomedical concept for each mention using the provided options. Answ... | <Mentions>: [x-linked retinoschisis]
<Options>: A: retinal dystrophy, x-linked, gardener-hardcastle type (homo sapiens) (aka retinal dystrophy, x-linked, gardener-hardcastle type)
B: rs1 (mus musculus) (retinoschisis (x-linked, juvenile) 1 (human) (mus musculus)) (aka retinoschisis (x-linked, juvenile) 1 (human))
C: re... | [E] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [neuronal cdk5 activator; cyclin-dependent protein kinase 5; cdk5]
<Options>: A: cdk5ps (homo sapiens) (aka cyclin dependent kinase 5 pseudogene 1)
B: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog (xenopus laevis)) (aka cyclin-dependent kinase 5, regulatory s... | [C; D; D] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [neuronal cdk5 activator; cyclin-dependent protein kinase 5; cdk5]
<Options>: A: cyclin dependent kinase 5 (mus musculus) (aka cyclin dependent kinase 5)
B: cdk5 (drosophila melanogaster) (aka cyclin-dependent kinase 5)
C: cdk5 (homo sapiens) (aka cyclin dependent kinase 5)
D: cyclin-dependent kinase 5 (dro... | [G; C; C] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [neuronal cdk5 activator; cyclin-dependent protein kinase 5; cdk5]
<Options>: A: cdk5ps (homo sapiens) (aka cyclin dependent kinase 5 pseudogene 1)
B: cyclin-dependent kinase 5 (drosophila melanogaster) (aka cyclin-dependent kinase 5)
C: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit... | [M; F; F] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [nck5a]
<Options>: A: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
B: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
C: nck1 (homo sapiens) (aka nck adaptor protein 1)
D: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory ... | [D] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c4a6 (homo sapiens) (aka complement c4a (chido/rodgers blood group))
B: c53a5.13 (caenorhabditis elegans) (aka fibronectin type-iii domain-containing protein)
C: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
D: c35c5.13 (caenorhabditis elegans) (aka ncrna)
E: nck1 (h... | [G; S; R; S] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
B: c82 (homo sapiens) (complement c8 beta chain (homo sapiens)) (aka complement c8 beta chain)
C: c34 (homo sapiens) (aka rna polymerase iii subunit f)
D: c4a6 (homo sapiens) (aka com... | [N; R; E; R] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: mm28 (homo sapiens) (aka matrix metallopeptidase 28)
B: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
C: c53 (mus musculus) (aka cdk5 regulatory subunit associated protein 3)
D: c35 (homo sapiens) (aka migration and invasion enhancer 1)
E: c5... | [R; S; N; S] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c53 (mus musculus) (aka cdk5 regulatory subunit associated protein 3)
B: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
C: c34 (homo sapiens) (aka rna polymerase iii subunit f)
D: c4a6 (homo sapiens) (aka complement c4a (chido/rod... | [M; S; G; S] |
<Instruct>: Given the context 'The three proteins show competitive binding to Nck5a suggesting that they bind at a common site.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a]
<Options>: A: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
B: nck1 (homo sapiens) (aka nck adaptor protein 1)
C: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
D: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
E: nck5ai (hom... | [D] |
<Instruct>: Given the context 'The binding site has been mapped to a region of 26 amino acid residues (residues 145 to 170) at the N-terminal boundary of the kinase activation domain of Nck5a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, on... | <Mentions>: [nck5a]
<Options>: A: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
B: nck1 (homo sapiens) (aka nck adaptor protein 1)
C: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
D: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
E: nek5 (... | [C] |
<Instruct>: Given the context 'This region of Nck5a contains an amphipathic alpha-helix whose hydrophobic face is involved in Cdk5 activation (Chin, K. T., Ohki, S, Tang, D., Cheng, H. C., Wang, J. H. , and Zhang, M. (1999) J. Biol.', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog (xenopus laevis)) (aka cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog)
B: cdk5 (drosophila melanogaster) (aka cyclin-dependent kinase 5)
C: cyclin dependent kinas... | [I; C] |
<Instruct>: Given the context 'This region of Nck5a contains an amphipathic alpha-helix whose hydrophobic face is involved in Cdk5 activation (Chin, K. T., Ohki, S, Tang, D., Cheng, H. C., Wang, J. H. , and Zhang, M. (1999) J. Biol.', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5 (mus musculus) (aka cyclin dependent kinase 5)
B: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
C: cdk5 (xenopus laevis) (aka cyclin-dependent kinase 5 l homeolog)
D: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
E: p35nck5a (hom... | [E; I] |
<Instruct>: Given the context 'Several lines of evidence suggest that Nck5a interacts with the binding proteins at the hydrophilic face of the amphipathic alpha-helix.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separ... | <Mentions>: [nck5a]
<Options>: A: nek5 (homo sapiens) (aka nima related kinase 5)
B: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
C: nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
D: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
E: nck5ai (xenopus tropic... | [C] |
<Instruct>: Given the context 'First, the Nck5a-(145-170) peptide can bind Cdk5 and Nck5a-binding proteins simultaneously.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog (xenopus laevis)) (aka cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog)
B: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
C: cdk5a (drosophila melanogaster... | [I; D] |
<Instruct>: Given the context 'First, the Nck5a-(145-170) peptide can bind Cdk5 and Nck5a-binding proteins simultaneously.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5 (mus musculus) (aka cyclin dependent kinase 5)
B: nek5 (homo sapiens) (aka nima related kinase 5)
C: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
D: cdk5 (homo sapiens) (aka cyclin dependent kinase 5)
E: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulato... | [I; D] |
<Instruct>: Given the context 'First, the Nck5a-(145-170) peptide can bind Cdk5 and Nck5a-binding proteins simultaneously.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5 (xenopus laevis) (aka cyclin-dependent kinase 5 l homeolog)
B: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog (xenopus laevis)) (aka cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog)
C: p35nck5a (homo sapie... | [E; D] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
B: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
D: cdk5ps (homo sapiens) (aka... | [B; L; J] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: complement c4a (rodgers blood group)-like (homo sapiens) (aka complement c4a (rodgers blood group)-like)
B: mm28 (homo sapiens) (aka matrix metallopeptidase 28)
C: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
D: mgc148328 (bos tauru... | [E; K; H] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: cdk5 (homo sapiens) (aka cyclin dependent kinase 5)
B: c56 (homo sapiens) (aka interferon induced protein with tetratricopeptide repeats 1)
C: mm28 (homo sapiens) (aka matrix metallopeptidase 28)
D: c48 (homo sapiens) (aka cdk5 regulatory subunit associated protein 2)
E: nck... | [O; D; A] |
<Instruct>: Given the context 'Third, substitution of Glu(157) by glutamine in Nck5a-(145-170) abolishes the peptide's ability to bind to the three Nck5a-binding proteins without diminishing its Cdk5 binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [nck5a; cdk5]
<Options>: A: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
B: cdk5 (xenopus laevis) (aka cyclin-dependent kinase 5 l homeolog)
C: cdk5 (homo sapiens) (aka cyclin dependent kinase 5)
D: nck (homo sapiens) (aka nck adaptor protein 1)
E: cdk5ps (homo sapiens) (aka cyclin dependent kinas... | [F; C] |
<Instruct>: Given the context 'Third, substitution of Glu(157) by glutamine in Nck5a-(145-170) abolishes the peptide's ability to bind to the three Nck5a-binding proteins without diminishing its Cdk5 binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [nck5a; cdk5]
<Options>: A: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
B: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
C: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
D: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory s... | [A; F] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
B: atypical chemokine receptor 3 (xenopus tropicalis) (aka atypical chemokine receptor 3)
C: ifi10 (homo sapiens) (aka ... | [L; F; I; C] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: colony stimulating factor 3 (granulocyte) (mus musculus) (aka colony stimulating factor 3 (granulocyte))
B: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif... | [B; C; Q; N] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
B: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
C: colony stimulating factor 3 ... | [M; G; O; Q] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating fact... | [T; J; A; S] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: cc-ckr-3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
C: interferon gamma (homo sapiens) (aka interfero... | [G; D; D; K] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: c-c motif chemokine receptor 3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3... | [C; B; B; P] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: c-c motif chemokine receptor 3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
C: c-x-c motif chemokine recepto... | [J; R; R; N] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
B: chemokine (c-c motif) receptor 3 (xenopus tropicalis) (aka chemokine (c-c motif... | [S; E; E; M] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: mip-1d (homo sapiens) (aka c-c motif chemokine ligand 15)
D: mig1 (homo sapiens) (aka vacuolar prot... | [J; A; A] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
B: midkine (homo sapiens) (aka midkine)
C: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: il-10c (homo sapiens) (aka interleukin 19)
E: mig (mus musculus) (aka c-x-c motif chem... | [N; F; F] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
B: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
C: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
D: il-10c (homo sapiens) (aka interleukin 19)
E: interleukin... | [B; M; M] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
B: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
C: ld78gamma (homo sapiens) (aka c-c motif chemokine ligand 3 pseudogene 1)
D: interleukin 1 family member 10 (homo sapiens) (... | [B; E; E] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
B: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: c-x3-c motif chemokine recept... | [L; F; O; O] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)
B: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
D: colony stimulating factor ... | [Q; G; R; R] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: myeloid derived growth factor (homo sapiens) (aka myeloid derived growth factor)
D: ... | [N; K; I; I] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: multi-csf (homo sapiens) (aka interleukin 3)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: cd344 (homo sapiens) (aka frizzled class receptor 4)
D: csf1 (homo sapiens) (aka colony stimul... | [G; F; Q; Q] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: myeloid derived growth factor (homo sapiens) (aka myeloid derived growth factor)
D: cd34 molec... | [G; F; M; M] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cd34]
<Options>: A: cd34 (sus scrofa) (aka cd34 molecule)
B: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
C: cd34 molecule (gallus gallus) (aka cd34 molecule)
D: cd344 (homo sapiens) (aka frizzled class receptor 4)
E: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
F... | [B] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: cd344 (homo sapiens) (aka frizzled class receptor 4)
B: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
C: multi-csf (homo sapiens) (aka interleukin 3)
D: cd34 (sus scrofa) (aka cd34 molecule)
E: cd114 (homo sapiens) (aka colony stimulatin... | [K; H; N] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: c-x-c motif chemokine receptor 3 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: fat4 (homo sapiens) (aka fat atypical cadherin 4... | [F; K; N] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: cd344 (homo sapiens) (aka frizzled class receptor 4)
B: cd34 (sus scrofa) (aka cd34 molecule)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
E: colony stimulating factor 1 (homo sapiens) (aka colony stimulat... | [K; L; J] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
B: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
E: mig-6 (mus musculu... | [R; H; F; J] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: il-10a (homo sapiens) (aka interleukin 10)
B: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
C: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
D: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
E: csf1 (homo sapiens) (aka colony s... | [M; I; H; P] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: gip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
E: multi-... | [C; L; T; Q] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
B: colony stimulating factor 2 (homo sapiens) (aka colony stimulating factor 2)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: cd34 (sus scrofa) (aka cd34 molecule... | [M; C; B; F] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: il-10a (homo sapiens) (aka interleukin 10)
B: cd344 (homo sapiens) (aka frizzled class receptor 4)
C: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
D: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
E: interleukin 1 family me... | [L; K; T; D] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
C: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
D: mig1 (homo sapiens) (aka vacuolar protein sorting 4 ... | [B; A; F] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
B: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: interleukin 1 family member 1... | [A; K; C] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
B: il-10c (homo sapiens) (aka interleukin 19)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: cxcr3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
E: interleukin 10 (homo sapiens) (aka i... | [D; I; C] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cd34]
<Options>: A: cd34 (sus scrofa) (aka cd34 molecule)
B: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
D: cd34 (gallus gallus) (aka cd34 molecule)
E: fat4 (homo sapiens) (aka fat atypical cadherin 4)
F: None of the... | [C] |
<Instruct>: Given the context 'These chemotactic attracted CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd34]
<Options>: A: cd34 molecule (gallus gallus) (aka cd34 molecule)
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
D: cd34 molecule (homo sapiens) (aka cd34 molecule)
E: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
F: ... | [D] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
B: cd34 (sus scrofa) (aka cd34 molecule)
C: cd344 (homo sapiens) (aka frizzled class receptor 4)
D: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
E... | [R; G; N; J] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
E... | [N; C; Q; R] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: multi-csf (homo sapiens) (aka interleukin 3)
B: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
C: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: cd344 (homo sapiens) (aka frizzled class receptor 4)
E: cd114 (homo... | [C; I; S; P] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: csf1 (homo sapiens) (aka colony stimulating factor 1)
B: mig9 (homo sapiens) (aka s100 calcium binding protein p)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
E: cd34 (homo sapiens) (... | [F; C; M; E] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
B: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
C: cc-ckr-3 (homo sapiens) (aka c-c motif chemokine receptor 3)
D: c-x-c motif chemokine receptor 3 (xenopus tropicalis) (aka c-x-c motif chemokine rece... | [L; J; F] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: interleukin 10 (homo sapiens) (aka interleukin 10)
D: pla2g10ip (homo sapiens) (aka phospho... | [I; N; G] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: mig9 (homo sapiens) (aka s100 calcium binding protein p)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: interleukin 10 (homo sapiens) (aka interleukin 10)
D: c-x-c motif chemokine receptor 3 gene 2 (xenopus tropicalis) (aka c-x... | [L; F; N] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [chemokine stromal cell-derived factor 1 alpha]
<Options>: A: sdf-1 (xenopus tropicalis) (aka c-x-c motif chemokine ligand 12)
B: mip-1-alpha (homo sapiens) (aka c-c motif chemokine ligand 3)
C: sdf2 (homo sapiens) (aka stromal cell derived factor 2)
D: sdf1 (homo sapiens) (aka c-x-c motif chemokine ligand ... | [D] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
B: cd49e (homo sapiens) (aka integrin subunit alpha 5)
C: glycoprotein ix platelet (homo sapiens) (aka glycoprotein ix platelet)
D: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
E: cd49fa... | [P; J; Q; G] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: il-10a (homo sapiens) (aka interleukin 10)
B: il-10c (homo sapiens) (aka interleukin 19)
C: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
D: cd49e (homo sapiens) (aka integrin subunit alpha 5)
E: mig11 (homo sapiens) (aka molybdenum cofactor synthes... | [G; F; I; Q] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
B: cd49b (homo sapiens) (aka integrin subunit alpha 2)
C: cd49a (homo sapiens) (aka integrin subunit alpha 1)
D: mig-6 (homo sapiens) (aka erbb receptor feedback inhibitor 1)
E: cd49fa (homo sapiens)... | [N; H; C; B] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
B: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
C: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
D: interleukin 10 (homo sapiens) (aka interleukin 10)
E: cd49fa (homo sapi... | [P; A; J; K] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gm-csf; cd34]
<Options>: A: multi-csf (homo sapiens) (aka interleukin 3)
B: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
C: fat4 (homo sapiens) (aka fat atypical cadherin 4)
D: cd34 molecule (gallus gallus) (aka cd34 molecule)
E: colony stimulating factor 3 (homo sapiens) (aka col... | [H; B] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gm-csf; cd34]
<Options>: A: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: cd34 molecule (gallus gallus) (aka cd34 molecule)
D: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
E: cd34 (homo sapiens) (cd34 molecule... | [G; E] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: il-10c (homo sapiens) (aka interleukin 19)
B: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
C: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
D: mig11 (homo sapiens) (aka molybdenum cof... | [F; G; S; E] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
B: colony stimulating factor 2 (homo sapiens) (aka colony stimulating factor 2)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: multi-csf (homo sapiens) (aka interleukin 3)
E: il-10a (hom... | [N; C; I; B] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
B: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
C: c-c motif chemokine receptor 3 (homo sapiens) (aka c-c motif chemokine receptor 3)
D: colony stimulating fac... | [P; S; L; O] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: interleukin 10 (homo sapiens) (aka interleukin 10)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
D: c-x3-c motif chemokine re... | [E; N; M; C] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [cd34]
<Options>: A: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
B: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: cd34 (sus scrofa) (aka cd34 molecule)
D: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)
E: cd34 (homo sapiens) (cd34 molecule (homo sapiens))... | [E] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
B: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
C: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
D: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)... | [D; N; K] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
B: il-10a (homo sapiens) (aka interleukin 10)
C: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
D: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
E: mig-6 (mus musculus) (aka erbb re... | [K; L; G] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: c-x-c motif chemokine ligand 10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
C: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
D: interleukin 10 (homo sapie... | [M; A; F] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [gm-csf; cd34]
<Options>: A: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
B: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
C: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
D: fat4 (homo sap... | [A; F] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [gm-csf; cd34]
<Options>: A: cd344 (homo sapiens) (aka frizzled class receptor 4)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
D: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)... | [H; J] |
<Instruct>: Given the context 'These processes include transmigration, relocation, differentiation, and maturation of CD34(+) hematopoietic progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicol... | <Mentions>: [cd34]
<Options>: A: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: cd34 (sus scrofa) (aka cd34 molecule)
D: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
E: cd114 (homo sapiens) (aka colony stimulating factor 3 r... | [A] |
<Instruct>: Given the context 'HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120; gp160]
<Options>: A: envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
B: gp160 (rattus norvegicus) (aka leucyl and cystinyl aminopeptidase)
C: envelope glycoprotein 150 (human gammaherpesvirus 4) (aka envelope glycop... | [A; A] |
<Instruct>: Given the context 'HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120; gp160]
<Options>: A: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
B: envelope glycoprotein 150 (human gammaherpesvirus 4) (aka envelope glycoprotein 150)
C: gp120 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 4)
D: gp160 (mus musculus) (aka leucyl/cystinyl aminop... | [F; F] |
<Instruct>: Given the context 'HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120; gp160]
<Options>: A: gp160 (homo sapiens) (aka glutamyl aminopeptidase)
B: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
C: envelope glycoprotein 150 (human gammaherpesvirus 4) (aka envelope glycoprotein 150)
D: gp120 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain ... | [I; I] |
<Instruct>: Given the context 'Recently, the alpha-chemokine receptor CXCR4 has been reported to mediate apoptosis in neuronal cells and in CD4(+) and CD8(+) T cells after its binding to HIV-1 envelope proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the s... | <Mentions>: [alpha-chemokine receptor cxcr4]
<Options>: A: cxcr4 (homo sapiens) (aka c-x-c motif chemokine receptor 4)
B: atypical chemokine receptor 4 (homo sapiens) (aka atypical chemokine receptor 4)
C: x-c motif chemokine receptor 1 (homo sapiens) (aka x-c motif chemokine receptor 1)
D: atypical chemokine receptor ... | [A] |
<Instruct>: Given the context 'In the current study, it was observed that human umbilical vein endothelial cells (HUVEC) undergo apoptosis after their treatment with the HIV-1 envelope proteins gp120/160.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [gp120/160]
<Options>: A: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
B: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
C: gp120 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 4)
D: mg-160 (rattus norvegicus) (aka golgi glycopro... | [B] |
<Instruct>: Given the context 'Anti-CXCR4 monoclonal antibody decreased HIV-1 gp120/160-induced apoptosis, suggesting that the CXCR4 chemokine receptor mediates the apoptotic effects of these HIV envelope glycoproteins.', select the correct biomedical concept for each mention using the provided options. Answer by listi... | <Mentions>: [cxcr4; gp120/160]
<Options>: A: c-x-c motif chemokine receptor 4 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 4)
B: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
C: mg160 (homo sapiens) (aka golgi glycoprotein 1)
D: atypical chemokine receptor 4 (xenopus tropicalis) (aka aty... | [J; H] |
<Instruct>: Given the context 'Anti-CXCR4 monoclonal antibody decreased HIV-1 gp120/160-induced apoptosis, suggesting that the CXCR4 chemokine receptor mediates the apoptotic effects of these HIV envelope glycoproteins.', select the correct biomedical concept for each mention using the provided options. Answer by listi... | <Mentions>: [cxcr4; gp120/160]
<Options>: A: c-c motif chemokine receptor 4 (homo sapiens) (aka c-c motif chemokine receptor 4)
B: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
C: c-c chemokine receptor type 8 (xenopus tropicalis) (aka c-c chemokine receptor type 8)
D: gp160 ... | [J; B] |
<Instruct>: Given the context 'Further studies revealed that caspases play an important role in this process because the pretreatment of cells with a general caspase enzyme inhibitor decreased the extent of HUVEC apoptosis induced by gp120/160.', select the correct biomedical concept for each mention using the provided... | <Mentions>: [gp120/160]
<Options>: A: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
B: gp120 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 4)
C: gp160 (rattus norvegicus) (aka leucyl and cystinyl aminopeptidase)
D: envelope surface glycoprotein gp160, precursor (human immunodeficienc... | [D] |
<Instruct>: Given the context 'In addition, it was found that caspase-3 was activated on HIV-1 gp120/160 treatment of these cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caspase-3; gp120/160]
<Options>: A: mg160 (homo sapiens) (aka golgi glycoprotein 1)
B: mg-160 (rattus norvegicus) (aka golgi glycoprotein 1)
C: gp160 (rattus norvegicus) (aka leucyl and cystinyl aminopeptidase)
D: ice-lap3 (homo sapiens) (aka caspase 7)
E: casp-3 (mus musculus) (aka caspase 3)
F: ich-3 (ho... | [H; J] |
<Instruct>: Given the context 'In addition, it was found that caspase-3 was activated on HIV-1 gp120/160 treatment of these cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caspase-3; gp120/160]
<Options>: A: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
B: caspase-3 (xenopus tropicalis) (aka caspase 3, gene 2)
C: caspase 3 (drosophila melanogaster) (death related ice-like caspase (drosophila melanogaster)) (aka death related ice-li... | [D; A] |
<Instruct>: Given the context 'It was also observed that gp120/160 treatment slightly increased the expression of the pro-apoptotic molecule Bax.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120/160; bax]
<Options>: A: mg160 (homo sapiens) (aka golgi glycoprotein 1)
B: bax (escherichia coli str. k-12 substr. mg1655) (aka putative glycoside hydrolase bax)
C: bcl2 associated x, apoptosis regulator (homo sapiens) (aka bcl2 associated x, apoptosis regulator)
D: gp160 (mus musculus) (aka leucyl/c... | [F; C] |
<Instruct>: Given the context 'It was also observed that gp120/160 treatment slightly increased the expression of the pro-apoptotic molecule Bax.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120/160; bax]
<Options>: A: envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
B: bax (escherichia coli str. k-12 substr. mg1655) (aka putative glycoside hydrolase bax)
C: bak-like (homo sapiens) (aka bcl2 antagonist/killer... | [A; H] |
<Instruct>: Given the context 'These results suggest that HIV-1 envelope glycoproteins can disrupt endothelial integrity through the interaction with CXCR4, thereby facilitating virus transit out of the bloodstream and contributing to the vascular injury syndromes seen in acquired immunodeficiency syndrome.', select th... | <Mentions>: [cxcr4]
<Options>: A: atypical chemokine receptor 4 (xenopus tropicalis) (aka atypical chemokine receptor 4)
B: chemokine (c motif) receptor 1 (xenopus tropicalis) (aka chemokine (c motif) receptor 1)
C: c-x-c motif chemokine receptor 4 (homo sapiens) (aka c-x-c motif chemokine receptor 4)
D: c-x-c motif ch... | [C] |
<Instruct>: Given the context 'Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome).
', select the correct biomedical concept for each mention using the provided options. Answer b... | <Mentions>: [collagen xviii]
<Options>: A: collagen type xviii alpha 1 (xenopus tropicalis) (aka collagen type xviii alpha 1)
B: collagen alpha-1(xxviii) chain (xenopus laevis) (aka collagen alpha-1(xxviii) chain)
C: collagen alpha-1(xxviii) chain (xenopus tropicalis) (aka collagen alpha-1(xxviii) chain)
D: collagen ty... | [E] |
<Instruct>: Given the context 'We reconstructed the haplotypes of this family with ten additional markers (five were novel) and narrowed the candidate interval to a region of < 245 kb, which contains 24 expressed sequence tags, the KIAA0958 gene and the 5' end of the COL18A1 gene.', select the correct biomedical concep... | <Mentions>: [kiaa0958; col18a1]
<Options>: A: col18a1 (xenopus tropicalis) (aka collagen type xviii alpha 1)
B: chromosome 5 c6orf58 homolog (xenopus tropicalis) (aka chromosome 5 c6orf58 homolog)
C: col18a1.s (xenopus laevis) (aka collagen type xviii alpha 1 s homeolog)
D: col18a1 (bos taurus) (aka collagen type xviii... | [K; H] |
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