instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
|---|---|---|
<Instruct>: Given the context 'Three RNA transcripts (3.6, 2.6, and 2.1 kilobases) were identified in poly(A+) RNA isolated from a gastric adenocarcinoma cell line that produced CTSE that were absent from nonproducing subclones.', select the correct biomedical concept for each mention using the provided options. Answer... | <Mentions>: [ctse]
<Options>: A: cathepsin e (homo sapiens) (aka cathepsin e)
B: ctse (mus musculus) (aka cathepsin e)
C: ctsa (homo sapiens) (aka cathepsin a)
D: ctsl (homo sapiens) (aka cathepsin l)
E: ctse (rattus norvegicus) (aka cathepsin e)
F: None of the above. | [A] |
<Instruct>: Given the context 'CTSE contains 7 cysteine residues, of which 6 were localized by comparative maximal alignment analysis with pepsinogen A to conserved residues that form intrachain disulfide bonds.', select the correct biomedical concept for each mention using the provided options. Answer by listing the s... | <Mentions>: [ctse]
<Options>: A: ctse (mus musculus) (aka cathepsin e)
B: ctsa (homo sapiens) (aka cathepsin a)
C: ctse (homo sapiens) (aka cathepsin e)
D: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
E: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
F: None o... | [C] |
<Instruct>: Given the context 'The seventh cysteine residue of CTSE is located within the activation peptide region of the proenzyme.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ctse]
<Options>: A: ctsa (homo sapiens) (aka cathepsin a)
B: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
C: ctse (rattus norvegicus) (aka cathepsin e)
D: cathepsin e (homo sapiens) (aka cathepsin e)
E: ctse (gallus gallus) (aka cathepsin e)
F: None of the ab... | [D] |
<Instruct>: Given the context 'We suspect that this residue forms an interchain disulfide bond and thereby determines the dimerization of CTSE proenzyme molecules that is observed under native conditions.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [ctse]
<Options>: A: ctsl (homo sapiens) (aka cathepsin l)
B: ctsa (homo sapiens) (aka cathepsin a)
C: ctse (mus musculus) (aka cathepsin e)
D: ctse (homo sapiens) (aka cathepsin e)
E: ctsh (homo sapiens) (aka cathepsin h)
F: None of the above. | [D] |
<Instruct>: Given the context 'The CTSE gene was localized to human chromosome 1 by concurrent cytogenetic and cDNA probe analyses of a panel of human x mouse somatic cell hybrids.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each m... | <Mentions>: [ctse]
<Options>: A: ctse (rattus norvegicus) (aka cathepsin e)
B: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
C: ctse (gallus gallus) (aka cathepsin e)
D: ctsh (homo sapiens) (aka cathepsin h)
E: ctse (homo sapiens) (aka cathepsin e)
F: None of the above. | [E] |
<Instruct>: Given the context 'Homology between a region of the human retinoblastoma gene and L1 family repetitive sequences.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [retinoblastoma]
<Options>: A: rb3 (homo sapiens) (aka stathmin 4)
B: p105-rb (homo sapiens) (aka rb transcriptional corepressor 1)
C: rb-1 (homo sapiens) (aka rna binding motif protein 45)
D: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
E: rb (drosophila melanogaster) (retinoblastoma-fami... | [B] |
<Instruct>: Given the context 'Five clones that hybridized weakly with the human retinoblastoma (Rb) gene were obtained by screening a human genomic library in a non-stringent condition.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for ... | <Mentions>: [retinoblastoma; rb]
<Options>: A: rbb (homo sapiens) (aka nacc family member 2)
B: rb (drosophila melanogaster) (retinoblastoma-family protein 2 (drosophila melanogaster)) (aka retinoblastoma-family protein 2)
C: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
D: rbl1 (homo sapiens) (aka rb ... | [H; H] |
<Instruct>: Given the context 'Five clones that hybridized weakly with the human retinoblastoma (Rb) gene were obtained by screening a human genomic library in a non-stringent condition.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for ... | <Mentions>: [retinoblastoma; rb]
<Options>: A: rb-1 (homo sapiens) (aka rna binding motif protein 45)
B: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
C: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
D: p105-rb (homo sapiens)... | [D; D] |
<Instruct>: Given the context 'The DNAs of two of these clones were partially sequenced and found to contain a region with considerable homology to part of the Rb gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, sepa... | <Mentions>: [rb]
<Options>: A: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
B: p105-rb (homo sapiens) (aka rb transcriptional corepressor 1)
C: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
D: rb3 (homo sapiens) (aka stathmin 4)
E: rb (drosophila melanogaster) (retinoblastoma-family ... | [B] |
<Instruct>: Given the context 'As the L1 family is transposable, the Rb gene may be inactivated by recombination at this homologous region.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rb]
<Options>: A: rbb (homo sapiens) (aka nacc family member 2)
B: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
C: p105-rb (homo sapiens) (aka rb transcriptional corepressor 1)
D: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
E: rb (drosophila melanogaster) (retinoblasto... | [C] |
<Instruct>: Given the context 'Another possibility related with the DNA binding properties of Rb and L1 family proteins is also discussed.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rb]
<Options>: A: rb (homo sapiens) (aka rb transcriptional corepressor 1)
B: rbb (homo sapiens) (aka nacc family member 2)
C: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
D: rb3 (homo sapiens) (aka stathmin 4)
E: rb-1 (homo sapiens) (aka rna binding motif protein 45)
F: None of the abov... | [A] |
<Instruct>: Given the context 'COUP transcription factor is a member of the steroid receptor superfamily.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [coup transcription factor]
<Options>: A: coup1 (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 2)
B: coup-tfi (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
C: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
D: coup-tfi (rattus nor... | [B] |
<Instruct>: Given the context 'The COUP (chicken ovalbumin upstream promoter) transcription factor (COUP-TF) exists in a number of different tissues and is essential for expression of the chicken ovalbumin gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the s... | <Mentions>: [coup (chicken ovalbumin upstream promoter) transcription factor; coup-tf]
<Options>: A: coup-tfi (rattus norvegicus) (aka nuclear receptor subfamily 2, group f, member 1)
B: coup-tfii (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 2)
C: coup-tfa (xenopus tropicalis) (aka nuclear rece... | [F; F] |
<Instruct>: Given the context 'The COUP (chicken ovalbumin upstream promoter) transcription factor (COUP-TF) exists in a number of different tissues and is essential for expression of the chicken ovalbumin gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the s... | <Mentions>: [coup (chicken ovalbumin upstream promoter) transcription factor; coup-tf]
<Options>: A: coup1 (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 2)
B: coup-tf (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
C: coup (xenopus laevis) (nuclear receptor subfamily 2, group f,... | [E; E] |
<Instruct>: Given the context 'COUP-TF also binds specifically to the rat insulin promoter element, although the two binding sites share little sequence similarity.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separate... | <Mentions>: [coup-tf]
<Options>: A: coup-tf (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
B: coup-tfi (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
C: couptfb (homo sapiens) (aka nuclear receptor subfamily 2 group f member 2)
D: coup-tfi (rattus norvegicus) (aka nuclear receptor ... | [B] |
<Instruct>: Given the context 'COUP-TF also binds specifically to the rat insulin promoter element, although the two binding sites share little sequence similarity.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separate... | <Mentions>: [coup-tf]
<Options>: A: coup-tfi (rattus norvegicus) (aka nuclear receptor subfamily 2, group f, member 1)
B: couptfb (homo sapiens) (aka nuclear receptor subfamily 2 group f member 2)
C: coup-tf (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
D: coup (xenopus laevis) (nuclear receptor subf... | [E] |
<Instruct>: Given the context 'Here we report the isolation of a human complementary DNA clone encoding COUP-TF.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [coup-tf]
<Options>: A: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
B: coup-tfi (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
C: coup-tfi (homo sapiens) (aka nuclear re... | [C] |
<Instruct>: Given the context 'Comparison of the amino-acid sequence of COUP-TF with known sequences reveals that it is a member of the steroid/thyroid hormone/vitamin receptor superfamily.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one f... | <Mentions>: [coup-tf]
<Options>: A: coup-tfa (xenopus tropicalis) (aka nuclear receptor subfamily 2, group f, member 5)
B: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
C: coup-tfii (xenopus tropicalis... | [D] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: cd25 (homo sapiens) (interleukin 2 receptor subunit alpha (homo sapiens)) (aka interleukin 2 receptor subunit alpha)
B: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
C: il2rb (homo sapiens) (aka interl... | [C; K; K; A] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
B: interleukin 1 receptor type 2 (homo sapiens) (aka interleukin 1 receptor type 2)
C: il2rb (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: il... | [C; G; G; D] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: csf2 (homo sapiens) (aka colony stimulating factor 2)
B: il2ra (homo sapiens) (aka interleukin 2 receptor subunit alpha)
C: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
D: il12rb (homo sapiens) (aka i... | [O; J; J; B] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
B: colony stimulating factor 2 receptor subunit alpha (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
C: ilf2 (homo sapiens) (aka interleukin enhance... | [E; G; G; F] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [interleukin-2 receptor beta; interleukin-2; il-2; il-2 receptor alpha]
<Options>: A: il22 (homo sapiens) (aka interleukin 22)
B: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
C: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
D: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
E:... | [K; I; I; E] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
B: il2r (homo sapiens) (aka interleukin 2 receptor subunit alpha)
C: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
D: csf2rb ... | [O; O; H; H] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
B: p-55 (homo sapiens) (aka peptidase, mitochondrial processing subunit alpha)
C: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit bet... | [F; F; G; G] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
B: p55-gamma (homo sapiens) (aka phosphoinositide-3-kinase regulatory subunit 3)
C: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit bet... | [L; L; H; H] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
B: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: il22r (homo sapiens) (aka i... | [O; O; J; J] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [il-2r alpha; p55; il-2 receptor beta; il-2r beta]
<Options>: A: csf2rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
B: il12rb2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
C: d55 (homo sapiens) (aka tpd52 like 3)
D: p55t (homo sapiens) (aka protein associated with l... | [F; F; K; K] |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, ... | <Mentions>: [p70-75]
<Options>: A: ck-75 (homo sapiens) (aka keratin 75)
B: pp75 (homo sapiens) (aka rab11 family interacting protein 5)
C: p70-75 (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: pp8675 (homo sapiens) (aka pml nuclear body scaffold)
E: hsp 75 (homo sapiens) (aka tnf receptor associated prote... | [C] |
<Instruct>: Given the context 'The cDNA encoding the human IL-2R beta chain has now been isolated.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-2r beta]
<Options>: A: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
B: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: interleukin 2 receptor subunit gamma (homo sapiens) (aka interleukin 2 receptor subunit gamma)
D: interleukin 12 re... | [B] |
<Instruct>: Given the context 'The overall primary structure of the IL-2R beta chain shows no apparent homology to other known receptors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-2r beta]
<Options>: A: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
B: colony stimulating factor 2 receptor subunit beta (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit ... | [C] |
<Instruct>: Given the context 'Unlike the IL-2R alpha chain, the IL-2R beta chain has a large cytoplasmic region in which a functional domain (or domains) mediating an intracellular signal transduction pathway (or pathways) may be embodied.', select the correct biomedical concept for each mention using the provided opt... | <Mentions>: [il-2r alpha; il-2r beta]
<Options>: A: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
B: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
C: il2r (homo sapiens) (aka interleukin 2 receptor subunit alpha)
D: il-2... | [F; G] |
<Instruct>: Given the context 'Unlike the IL-2R alpha chain, the IL-2R beta chain has a large cytoplasmic region in which a functional domain (or domains) mediating an intracellular signal transduction pathway (or pathways) may be embodied.', select the correct biomedical concept for each mention using the provided opt... | <Mentions>: [il-2r alpha; il-2r beta]
<Options>: A: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
B: colony stimulating factor 2 receptor subunit beta (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 rece... | [F; C] |
<Instruct>: Given the context 'The cDNA-encoded beta chain binds and internalizes IL-2 when expressed on T lymphoid cells but not fibroblast cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-2]
<Options>: A: il-2 (homo sapiens) (aka interleukin 2)
B: interleukin 3 (homo sapiens) (aka interleukin 3)
C: il22 (homo sapiens) (aka interleukin 22)
D: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
E: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
F: None of the above. | [A] |
<Instruct>: Given the context 'Furthermore, the cDNA gives rise to the generation of high-affinity IL-2 receptor when co-expressed with the IL-2R alpha chain cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated... | <Mentions>: [il-2 receptor; il-2r alpha]
<Options>: A: ifn-r-2 (homo sapiens) (aka interferon alpha and beta receptor subunit 2)
B: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
C: colony stimulating factor 2 receptor subunit alpha (homo sapiens) (aka colony stimulating factor 2 receptor subunit alph... | [H; E] |
<Instruct>: Given the context 'Furthermore, the cDNA gives rise to the generation of high-affinity IL-2 receptor when co-expressed with the IL-2R alpha chain cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated... | <Mentions>: [il-2 receptor; il-2r alpha]
<Options>: A: interleukin 2 receptor subunit gamma (homo sapiens) (aka interleukin 2 receptor subunit gamma)
B: colony stimulating factor 2 receptor subunit beta (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
C: colony stimulating factor 2 receptor subuni... | [D; E] |
<Instruct>: Given the context 'Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ldl receptor]
<Options>: A: oxidized low density lipoprotein receptor 1 (homo sapiens) (aka oxidized low density lipoprotein receptor 1)
B: ldlr (homo sapiens) (aka low density lipoprotein receptor)
C: low density lipoprotein receptor (sus scrofa) (aka low density lipoprotein receptor)
D: apolipoprotein b ... | [B] |
<Instruct>: Given the context 'The pathogenesis of Heymann nephritis, a rat model of human membranous glomerulonephritis, depends on the interaction of autoantibodies with a renal glycoprotein (GP330) on glomerular podocytes.', select the correct biomedical concept for each mention using the provided options. Answer by... | <Mentions>: [gp330]
<Options>: A: gp330 (homo sapiens) (aka ldl receptor related protein 2)
B: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 l homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 l homeolog)
C: gp43 (xenopus laevis) (provisional ortholog of zona pellucida glycoprotein 3 s h... | [A] |
<Instruct>: Given the context 'Partial complementary DNAs coding for GP330 were isolated and sequenced.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp330]
<Options>: A: gp330 (homo sapiens) (aka ldl receptor related protein 2)
B: gp330 (xenopus tropicalis) (aka ldl receptor related protein 2)
C: gp43 (xenopus laevis) (provisional ortholog of zona pellucida glycoprotein 3 s homeolog (xenopus laevis)) (aka provisional ortholog of zona pellucida glycopro... | [A] |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept for each mention using the prov... | <Mentions>: [low density lipoprotein (ldl) receptor; gp330; ldl receptor]
<Options>: A: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 s homeolog)
B: gp280 (homo sapiens) (aka cubilin)
C: low density lipoprotein receptor (gallus gallus) ... | [I; D; I] |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept for each mention using the prov... | <Mentions>: [low density lipoprotein (ldl) receptor; gp330; ldl receptor]
<Options>: A: gp330 (xenopus tropicalis) (aka ldl receptor related protein 2)
B: very low density lipoprotein receptor (homo sapiens) (aka very low density lipoprotein receptor)
C: low density lipoprotein receptor (gallus gallus) (aka low density... | [D; N; D] |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept for each mention using the prov... | <Mentions>: [low density lipoprotein (ldl) receptor; gp330; ldl receptor]
<Options>: A: oxidized low density lipoprotein receptor 1 (homo sapiens) (aka oxidized low density lipoprotein receptor 1)
B: gp340 (homo sapiens) (aka deleted in malignant brain tumors 1)
C: very low density lipoprotein receptor (gallus gallus) ... | [G; D; G] |
<Instruct>: Given the context 'Autoantibodies from the kidneys of rats with Heymann nephritis reacted with a nonglycosylated segment of GP330 that contains cysteine-rich 40-amino acid repeats, which are also features of the LDL receptor.', select the correct biomedical concept for each mention using the provided option... | <Mentions>: [gp330; ldl receptor]
<Options>: A: low density lipoprotein receptor (sus scrofa) (aka low density lipoprotein receptor)
B: ldl receptor related protein 1 (homo sapiens) (aka ldl receptor related protein 1)
C: ldlr (homo sapiens) (aka low density lipoprotein receptor)
D: gp340 (xenopus laevis) (deleted in m... | [J; C] |
<Instruct>: Given the context 'Autoantibodies from the kidneys of rats with Heymann nephritis reacted with a nonglycosylated segment of GP330 that contains cysteine-rich 40-amino acid repeats, which are also features of the LDL receptor.', select the correct biomedical concept for each mention using the provided option... | <Mentions>: [gp330; ldl receptor]
<Options>: A: apolipoprotein b receptor (homo sapiens) (aka apolipoprotein b receptor)
B: very low density lipoprotein receptor (gallus gallus) (aka very low density lipoprotein receptor)
C: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka d... | [J; I] |
<Instruct>: Given the context 'Autoantibodies from the kidneys of rats with Heymann nephritis reacted with a nonglycosylated segment of GP330 that contains cysteine-rich 40-amino acid repeats, which are also features of the LDL receptor.', select the correct biomedical concept for each mention using the provided option... | <Mentions>: [gp330; ldl receptor]
<Options>: A: gp330 (xenopus tropicalis) (aka ldl receptor related protein 2)
B: very low density lipoprotein receptor (homo sapiens) (aka very low density lipoprotein receptor)
C: low density lipoprotein receptor (homo sapiens) (aka low density lipoprotein receptor)
D: gp280 (homo sap... | [I; C] |
<Instruct>: Given the context 'GP330 is also similar in some regions to the mouse epidermal growth factor precursor.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp330]
<Options>: A: gp330 (xenopus laevis) (aka ldl receptor related protein 2 l homeolog)
B: gp330 (homo sapiens) (aka ldl receptor related protein 2)
C: gp340 (homo sapiens) (aka deleted in malignant brain tumors 1)
D: gp280 (homo sapiens) (aka cubilin)
E: gp330 (xenopus tropicalis) (aka ldl receptor re... | [B] |
<Instruct>: Given the context 'Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrna polyadenylate binding protein]
<Options>: A: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-binding protein 1)
B: polyadenylate-binding protein 1-like (xenopus laevis) (aka polyadenylate-binding protein 1-like)
C: pabp (homo sapiens) (aka poly(a) binding protein cytoplasmic ... | [C] |
<Instruct>: Given the context 'We have isolated a full length cDNA (cDNA) coding for the human poly(A) binding protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [poly(a) binding protein]
<Options>: A: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-binding protein 1)
B: poly(a) binding protein cytoplasmic 1 (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
C: poly(a)-binding protein (arabidopsis thaliana) (aka poly(a)-binding prot... | [B] |
<Instruct>: Given the context 'The cDNA derived 73 kd basic translation product has the same Mr, isoelectric point and peptidic map as the poly(A) binding protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated... | <Mentions>: [poly(a) binding protein]
<Options>: A: poly(a) binding protein (drosophila melanogaster) (aka poly(a) binding protein)
B: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-binding protein 1)
C: pabp (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
D: pabp (xenopus tropical... | [C] |
<Instruct>: Given the context 'The N terminal part, highly homologous to the yeast poly(A) binding protein, is sufficient for poly(A) binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolo... | <Mentions>: [poly(a) binding protein]
<Options>: A: poly(a)-binding protein (arabidopsis thaliana) (aka poly(a)-binding protein 5)
B: poly(a) binding protein cytoplasmic 1 (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
C: poly(a) binding protein 1 (arabidopsis thaliana) (aka poly(a) binding protein 1)
D: po... | [B] |
<Instruct>: Given the context 'Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c1; c8]
<Options>: A: hho.c8 (homo sapiens) (aka homeobox c6)
B: scg8 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
C: m8 (homo sapiens) (aka prion locus lncrna, testis expressed)
D: c1_c (homo sapiens) (aka endogenous retrovirus group k member 18)
E: homeobox c8 (homo sapien... | [H; E] |
<Instruct>: Given the context 'Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c1; c8]
<Options>: A: homeobox c8 (homo sapiens) (aka homeobox c8)
B: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
C: m8 (homo sapiens) (aka prion locus lncrna, testis expressed)
D: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
E: hho.c1 (homo sapiens) (aka homeobox b7... | [E; A] |
<Instruct>: Given the context 'Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opti... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: o8 (homo sapiens) (aka immunoglobulin kappa variable 1d-33)
B: one cut homeobox 1 (homo sapiens) (aka one cut homeobox 1)
C: c8c (homo sapiens) (aka complement c8 gamma chain)
D: host cell factor c1 (homo sapiens) (aka host cell factor c1)
E: coh1 (homo sapiens) (aka vacuolar ... | [J; F] |
<Instruct>: Given the context 'Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opti... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: one cut homeobox 1 (homo sapiens) (aka one cut homeobox 1)
B: hha8 (homo sapiens) (aka keratin 38)
C: hho.c1 (homo sapiens) (aka homeobox b7)
D: hho.c1 (xenopus tropicalis) (aka homeobox b7)
E: hc1 (homo sapiens) (aka cycs pseudogene 39)
F: hoxc8 (homo sapiens) (aka homeobox c... | [C; F] |
<Instruct>: Given the context 'Expression of the corresponding genes, termed c1 and c8, was evaluated in different organs and body parts during human embryonic/fetal development.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each men... | <Mentions>: [c1; c8]
<Options>: A: host cell factor c1 (bos taurus) (aka host cell factor c1)
B: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
C: c8c (homo sapiens) (aka complement c8 gamma chain)
D: homeobox c8 (homo sapiens) (aka homeobox c8)
E: c1_c (homo sapiens) (aka endogenous retrovirus group k... | [F; D] |
<Instruct>: Given the context 'Expression of the corresponding genes, termed c1 and c8, was evaluated in different organs and body parts during human embryonic/fetal development.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each men... | <Mentions>: [c1; c8]
<Options>: A: m8 (homo sapiens) (aka prion locus lncrna, testis expressed)
B: homeobox c8 (homo sapiens) (aka homeobox c8)
C: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
D: c1r (homo sapiens) (aka complement c1r)
E: c1_c (homo sapiens) (aka endogeno... | [I; B] |
<Instruct>: Given the context 'HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111', select the correct biomedical concept for each mention using the provided options... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: hoxc8 (homo sapiens) (aka homeobox c8)
B: ch1 (homo sapiens) (aka sun domain containing ossification factor)
C: hhc1 (homo sapiens) (aka calcium sensing receptor)
D: hc1 (homo sapiens) (aka cycs pseudogene 39)
E: hho.c8 (homo sapiens) (aka homeobox c6)
F: hoxc8 (xenopus laevis... | [J; A] |
<Instruct>: Given the context 'HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111', select the correct biomedical concept for each mention using the provided options... | <Mentions>: [hho.c1; hho.c8]
<Options>: A: one cut homeobox 1 (homo sapiens) (aka one cut homeobox 1)
B: homeobox c8 (homo sapiens) (aka homeobox c8)
C: coh1 (homo sapiens) (aka vacuolar protein sorting 13 homolog b)
D: atoh8 (homo sapiens) (aka atonal bhlh transcription factor 8)
E: c8c (homo sapiens) (aka complement ... | [I; B] |
<Instruct>: Given the context 'encodes a 153-amino acid protein containing a homeodomain identical to that of the frog AC1 gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ac1]
<Options>: A: aconitate decarboxylase 1 (homo sapiens) (aka aconitate decarboxylase 1)
B: ac1 (homo sapiens) (adenylate cyclase 1 (homo sapiens)) (aka adenylate cyclase 1)
C: acyp1 (homo sapiens) (aka acylphosphatase 1)
D: acetyl-coa acetyltransferase 1 (homo sapiens) (aka acetyl-coa acetyltransferase... | [F] |
<Instruct>: Given the context 'Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hho.c1; hho.c8]
<Options>: A: atoh8 (homo sapiens) (aka atonal bhlh transcription factor 8)
B: hoxc8 (homo sapiens) (aka homeobox c8)
C: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
D: hho.c1 (homo sapiens) (aka homeobox b7)
E: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laev... | [D; B] |
<Instruct>: Given the context 'Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hho.c1; hho.c8]
<Options>: A: hh8 (homo sapiens) (aka kiss1 receptor)
B: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
C: hho.c1 (homo sapiens) (aka homeobox b7)
D: hc1 (homo sapiens) (aka cycs pseudogene 39)
E: one cut homeobox 1 (homo sapiens) (aka one cut ... | [C; G] |
<Instruct>: Given the context 'These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes.',... | <Mentions>: [c1; c8]
<Options>: A: c1in (homo sapiens) (aka serpin family g member 1)
B: homeobox c8 (homo sapiens) (aka homeobox c8)
C: hho.c8 (homo sapiens) (aka homeobox c6)
D: c8c (homo sapiens) (aka complement c8 gamma chain)
E: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
F: m8 (drosophila mel... | [I; B] |
<Instruct>: Given the context 'These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes.',... | <Mentions>: [c1; c8]
<Options>: A: c1in (homo sapiens) (aka serpin family g member 1)
B: m8 (drosophila melanogaster) (enhancer of split m8, helix-loop-helix (drosophila melanogaster)) (aka enhancer of split m8, helix-loop-helix)
C: complement c1r (homo sapiens) (aka complement c1r)
D: c1_a (homo sapiens) (aka endogeno... | [J; E] |
<Instruct>: Given the context 'These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes.',... | <Mentions>: [c1; c8]
<Options>: A: m8 (drosophila melanogaster) (enhancer of split m8, helix-loop-helix (drosophila melanogaster)) (aka enhancer of split m8, helix-loop-helix)
B: homeobox c8 (homo sapiens) (aka homeobox c8)
C: c1s (homo sapiens) (aka complement c1s)
D: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xe... | [J; B] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: homeobox c8 (homo sapiens) (aka homeobox c8)
B: m8 (drosophila melanogaster) (enhancer of split m8, helix-loop-helix (drosophila melanogaster)) (aka enhancer of split m8, helix-loop-helix)
C: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s... | [S; A; G; F] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: o13 (homo sapiens) (aka immunoglobulin kappa variable 2-38 (pseudogene))
B: ck13 (homo sapiens) (aka keratin 13)
C: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
D: c13 (homo sapiens) (aka spt20 homolog, saga complex component)
E: c1s (homo sapiens) (aka co... | [T; Q; L; S] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: homeobox c8 (homo sapiens) (aka homeobox c8)
B: scg8 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
C: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
D: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeo... | [T; A; H; R] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: carbonic anhydrase 13 (homo sapiens) (aka carbonic anhydrase 13)
B: gene rich cluster, c10 gene (danio rerio) (aka gene rich cluster, c10 gene)
C: homeobox c8 (homo sapiens) (aka homeobox c8)
D: hho.c13 (homo sapiens) (aka homeobox d4)
E: hc10 (homo sapiens) (aka cycs pseudo... | [G; C; J; T] |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept for each mention using the provided optio... | <Mentions>: [c1; c8; c10; c13]
<Options>: A: c1in (homo sapiens) (aka serpin family g member 1)
B: carbonic anhydrase 13 (homo sapiens) (aka carbonic anhydrase 13)
C: hho.c10 (homo sapiens) (aka homeobox b5)
D: c8c (homo sapiens) (aka complement c8 gamma chain)
E: m8 (drosophila melanogaster) (enhancer of split m8, hel... | [M; I; T; G] |
<Instruct>: Given the context 'Studies of the human c-myb gene and its product in human acute leukemias.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb]
<Options>: A: myb (mus musculus) (aka myeloblastosis oncogene)
B: c-myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
C: mybp-c (homo sapiens) (aka myosin binding protein c3)
D: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
E: b-myb (homo sapiens) (aka myb proto-oncogene ... | [B] |
<Instruct>: Given the context 'The myb gene is the transforming oncogene of the avian myeloblastosis virus (AMV); its normal cellular homolog, c-myb, is conserved across a broad span of evolution.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options... | <Mentions>: [myb; c-myb]
<Options>: A: mybp-c (homo sapiens) (aka myosin binding protein c3)
B: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
C: myb (drosophila melanogaster) (aka myb oncogene-like)
D: myb proto-oncogene like 1 (homo sapiens) (aka myb proto-oncogene like 1)
E: myb (mus musculus) (aka myelob... | [F; F] |
<Instruct>: Given the context 'The myb gene is the transforming oncogene of the avian myeloblastosis virus (AMV); its normal cellular homolog, c-myb, is conserved across a broad span of evolution.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options... | <Mentions>: [myb; c-myb]
<Options>: A: myb-1a (mus musculus) (aka y box protein 1)
B: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
C: myb proto-oncogene like 1 (homo sapiens) (aka myb proto-oncogene like 1)
D: myb (mus musculus) (aka myeloblastosis oncogene)
E: mybp-c (homo sapiens) (aka myosin binding pro... | [G; G] |
<Instruct>: Given the context 'In humans, c-myb is expressed in malignant hematopoietic cell lines and in primary hematopoietic tumors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb]
<Options>: A: mybp-c (homo sapiens) (aka myosin binding protein c3)
B: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
C: myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
D: myb (mus musculus) (aka myeloblastosis oncogene)
E: a-myb (homo sapiens) (aka myb proto-oncogene li... | [C] |
<Instruct>: Given the context 'The sequences of the clones were compared to the c-myb of other species, as well as the v-myb of AMV.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb; v-myb]
<Options>: A: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
B: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
C: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
D: v-myb avian myeloblastosis viral oncogene homolog (danio rerio) (aka v-myb avian myeloblastosis viral onco... | [F; F] |
<Instruct>: Given the context 'The sequences of the clones were compared to the c-myb of other species, as well as the v-myb of AMV.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb; v-myb]
<Options>: A: mybp-c (homo sapiens) (aka myosin binding protein c3)
B: myb (mus musculus) (aka myeloblastosis oncogene)
C: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
D: c-myb (mus musculus) (aka myeloblastosis oncogene)
E: myb proto-oncogene, transcription factor (gallus gallus... | [G; G] |
<Instruct>: Given the context 'In addition, the carboxyl terminal region of human c-myb was placed in an expression vector to obtain protein for the generation of antiserum, which was used to identify the human c-myb gene product.', select the correct biomedical concept for each mention using the provided options. Answ... | <Mentions>: [c-myb]
<Options>: A: mybp-c (homo sapiens) (aka myosin binding protein c3)
B: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
C: myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
D: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
E: b-myb (mus musculus) (aka myeloblastosis oncogen... | [C] |
<Instruct>: Given the context 'Like v-myb, this protein was found within the nucleus of leukemic cells where it was associated with the nuclear matrix.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolo... | <Mentions>: [v-myb]
<Options>: A: c-myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
B: v-myb avian myeloblastosis viral oncogene homolog (danio rerio) (aka v-myb avian myeloblastosis viral oncogene homolog)
C: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
D: myb proto-oncogene, transcripti... | [A] |
<Instruct>: Given the context 'Like v-myb, this protein was found within the nucleus of leukemic cells where it was associated with the nuclear matrix.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolo... | <Mentions>: [v-myb]
<Options>: A: b-myb (mus musculus) (aka myeloblastosis oncogene-like 2)
B: a-myb (homo sapiens) (aka myb proto-oncogene like 1)
C: v-myb avian myeloblastosis viral oncogene homolog (danio rerio) (aka v-myb avian myeloblastosis viral oncogene homolog)
D: myb proto-oncogene, transcription factor (gall... | [E] |
<Instruct>: Given the context 'These studies provide further evidence that c-myb might be involved in human leukemia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c-myb]
<Options>: A: b-myb (homo sapiens) (aka myb proto-oncogene like 2)
B: myb proto-oncogene like 1 (homo sapiens) (aka myb proto-oncogene like 1)
C: c-myb (homo sapiens) (aka myb proto-oncogene, transcription factor)
D: mybp-c (homo sapiens) (aka myosin binding protein c3)
E: myb (mus musculus) (aka my... | [C] |
<Instruct>: Given the context 'Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number.
cDNA clones for human B creatine kinase were isolated from human brain and placenta libraries.', select the correct biomed... | <Mentions>: [b creatine kinase]
<Options>: A: creatine kinase b (rattus norvegicus) (aka creatine kinase b)
B: creatine kinase b (bos taurus) (aka creatine kinase b)
C: creatine kinase b (homo sapiens) (aka creatine kinase b)
D: ckb (mus musculus) (creatine kinase, brain (mus musculus)) (aka creatine kinase, brain)
E: ... | [C] |
<Instruct>: Given the context 'A 77.7% nucleotide sequence identity was found between the coding region of human B creatine kinase and our previously reported human M creatine kinase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [b creatine kinase; m creatine kinase]
<Options>: A: creatine kinase b (gallus gallus) (aka creatine kinase b)
B: ckb (mus musculus) (creatine kinase, brain (mus musculus)) (aka creatine kinase, brain)
C: ckm (mus musculus) (aka creatine kinase, muscle)
D: cpk-m (mus musculus) (aka phosphatidylinositol-4-ph... | [I; G] |
<Instruct>: Given the context 'A 77.7% nucleotide sequence identity was found between the coding region of human B creatine kinase and our previously reported human M creatine kinase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [b creatine kinase; m creatine kinase]
<Options>: A: cpk-m (mus musculus) (aka phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha)
B: creatine kinase b (gallus gallus) (aka creatine kinase b)
C: ckb (homo sapiens) (creatine kinase b (homo sapiens)) (aka creatine kinase b)
D: creatine k... | [C; F] |
<Instruct>: Given the context 'Southern transfers of total genomic DNA derived from human placenta and digested to completion with several restriction enzymes were probed with the MCK and BCK specific probes producing single hybridization bands.', select the correct biomedical concept for each mention using the provide... | <Mentions>: [mck; bck]
<Options>: A: mlk (mus musculus) (aka muscle, skeletal, receptor tyrosine kinase)
B: bckb (homo sapiens) (aka creatine kinase b)
C: cmk (mus musculus) (aka c-x-c motif chemokine ligand 9)
D: bckdk (bos taurus) (aka branched chain keto acid dehydrogenase kinase)
E: mck (mus musculus) (aka creatine... | [K; B] |
<Instruct>: Given the context 'Southern transfers of total genomic DNA derived from human placenta and digested to completion with several restriction enzymes were probed with the MCK and BCK specific probes producing single hybridization bands.', select the correct biomedical concept for each mention using the provide... | <Mentions>: [mck; bck]
<Options>: A: serine/threonine/tyrosine protein kinase mck1 (saccharomyces cerevisiae s288c) (aka serine/threonine/tyrosine protein kinase mck1)
B: mlk (mus musculus) (aka muscle, skeletal, receptor tyrosine kinase)
C: ccnk (mus musculus) (aka cyclin k)
D: mck (mus musculus) (aka creatine kinase,... | [K; J] |
<Instruct>: Given the context 'Southern transfers of total genomic DNA derived from human placenta and digested to completion with several restriction enzymes were probed with the MCK and BCK specific probes producing single hybridization bands.', select the correct biomedical concept for each mention using the provide... | <Mentions>: [mck; bck]
<Options>: A: mck (mus musculus) (aka creatine kinase, muscle)
B: blk proto-oncogene, src family tyrosine kinase (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
C: mlk (mus musculus) (aka muscle, skeletal, receptor tyrosine kinase)
D: blk (homo sapiens) (aka blk proto-oncogene, ... | [J; J] |
<Instruct>: Given the context 'Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [dna polymerase delta]
<Options>: A: dna polymerase theta (homo sapiens) (aka dna polymerase theta)
B: dna polymerase delta 1, catalytic subunit (homo sapiens) (aka dna polymerase delta 1, catalytic subunit)
C: dna polymerase delta 2, accessory subunit (homo sapiens) (aka dna polymerase delta 2, accessory s... | [B] |
<Instruct>: Given the context 'Previous studies have specifically implicated DNA polymerase delta as the enzyme involved in DNA repair synthesis occurring immediately after UV damage.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [dna polymerase delta]
<Options>: A: dna polymerase delta 1, catalytic subunit (homo sapiens) (aka dna polymerase delta 1, catalytic subunit)
B: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
C: dna polymerase theta (homo sapiens) (aka dna polymerase... | [A] |
<Instruct>: Given the context 'In permeable cells, the process was further analyzed by using the nucleotide analogue (butylphenyl)-2'-deoxyguanosine 5'-triphosphate, which inhibits DNA polymerase alpha several hundred times more strongly than it inhibits DNA polymerase delta.', select the correct biomedical concept for... | <Mentions>: [dna polymerase alpha; dna polymerase delta]
<Options>: A: dna polymerase delta 3, accessory subunit (homo sapiens) (aka dna polymerase delta 3, accessory subunit)
B: dna polymerase iii subunit delta (escherichia coli str. k-12 substr. mg1655) (aka dna polymerase iii subunit delta)
C: dna polymerase epsilon... | [G; H] |
<Instruct>: Given the context 'In permeable cells, the process was further analyzed by using the nucleotide analogue (butylphenyl)-2'-deoxyguanosine 5'-triphosphate, which inhibits DNA polymerase alpha several hundred times more strongly than it inhibits DNA polymerase delta.', select the correct biomedical concept for... | <Mentions>: [dna polymerase alpha; dna polymerase delta]
<Options>: A: dna polymerase delta 3, accessory subunit (homo sapiens) (aka dna polymerase delta 3, accessory subunit)
B: dna polymerase eta (homo sapiens) (aka dna polymerase eta)
C: dna polymerase iota (homo sapiens) (aka dna polymerase iota)
D: dna polymerase ... | [G; H] |
<Instruct>: Given the context 'The (butylphenyl)-2'-deoxyguanosine 5'-triphosphate inhibition curve for late UV-induced repair synthesis was very similar to that for polymerase delta.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for eac... | <Mentions>: [polymerase delta]
<Options>: A: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
B: dna polymerase lambda (homo sapiens) (aka dna polymerase lambda)
C: dna polymerase delta 2, accessory subunit (homo sapiens) (aka dna polymerase delta 2, accessory sub... | [D] |
<Instruct>: Given the context 'It appears that repair synthesis at late times after UV irradiation, like repair synthesis at early times, is mediated by DNA polymerase delta.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention... | <Mentions>: [dna polymerase delta]
<Options>: A: dna polymerase delta 2, accessory subunit (homo sapiens) (aka dna polymerase delta 2, accessory subunit)
B: dna polymerase delta 3, accessory subunit (homo sapiens) (aka dna polymerase delta 3, accessory subunit)
C: dna polymerase lambda (homo sapiens) (aka dna polymeras... | [D] |
<Instruct>: Given the context 'Molecular cloning and primary structure of human 15-lipoxygenase.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [15-lipoxygenase]
<Options>: A: 15-lox (oryctolagus cuniculus) (aka arachidonate 15-lipoxygenase)
B: 15-lox (homo sapiens) (aka arachidonate 15-lipoxygenase)
C: arachidonate 5-lipoxygenase (homo sapiens) (aka arachidonate 5-lipoxygenase)
D: arachidonate 15-lipoxygenase (rattus norvegicus) (aka arachidonate ... | [B] |
<Instruct>: Given the context 'A full-length cDNA encoding 15-lipoxygenase has been isolated from a human reticulocyte cDNA library.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [15-lipoxygenase]
<Options>: A: 15-lox (homo sapiens) (aka arachidonate 15-lipoxygenase)
B: 15-lox-2 (homo sapiens) (aka arachidonate 15-lipoxygenase type b)
C: arachidonate 5-lipoxygenase (homo sapiens) (aka arachidonate 5-lipoxygenase)
D: 15-lox (oryctolagus cuniculus) (aka arachidonate 15-lipoxygenase)
E... | [A] |
<Instruct>: Given the context 'A full-length cDNA encoding 15-lipoxygenase has been isolated from a human reticulocyte cDNA library.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [15-lipoxygenase]
<Options>: A: arachidonate 15-lipoxygenase (rattus norvegicus) (aka arachidonate 15-lipoxygenase)
B: 15-lox (oryctolagus cuniculus) (aka arachidonate 15-lipoxygenase)
C: arachidonate 5-lipoxygenase (homo sapiens) (aka arachidonate 5-lipoxygenase)
D: 15-lox-2 (homo sapiens) (aka arachidonat... | [E] |
<Instruct>: Given the context 'The predicted primary structure of the enzyme exhibits a sequence similarity of 61% and 45% with human 5-lipoxygenase and the soybean lipoxygenase isoenzyme I, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [5-lipoxygenase; lipoxygenase isoenzyme i]
<Options>: A: loxl1 (homo sapiens) (aka lysyl oxidase like 1)
B: arachidonate 15-lipoxygenase (homo sapiens) (aka arachidonate 15-lipoxygenase)
C: lipoxygenase l-5 (glycine max) (aka lipoxygenase l-5)
D: lox1 (homo sapiens) (aka oxidized low density lipoprotein rec... | [E; J] |
<Instruct>: Given the context 'The predicted primary structure of the enzyme exhibits a sequence similarity of 61% and 45% with human 5-lipoxygenase and the soybean lipoxygenase isoenzyme I, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [5-lipoxygenase; lipoxygenase isoenzyme i]
<Options>: A: arachidonate 5-lipoxygenase (homo sapiens) (aka arachidonate 5-lipoxygenase)
B: lox (homo sapiens) (aka lysyl oxidase)
C: linoleate 9s-lipoxygenase 1 (glycine max) (aka linoleate 9s-lipoxygenase 1)
D: 15-lox (homo sapiens) (aka arachidonate 15-lipoxyg... | [A; K] |
<Instruct>: Given the context 'Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by sem... | <Mentions>: [srf; c-fos]
<Options>: A: c-fos (mus musculus) (aka fbj osteosarcoma oncogene)
B: serum response factor homolog (caenorhabditis elegans) (aka serum response factor homolog)
C: serum response factor (homo sapiens) (aka serum response factor)
D: fos proto-oncogene, ap-1 transcription factor subunit (homo sap... | [C; D] |
<Instruct>: Given the context 'Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by sem... | <Mentions>: [srf; c-fos]
<Options>: A: serum response factor homolog (caenorhabditis elegans) (aka serum response factor homolog)
B: c-fos (xenopus laevis) (fbj murine osteosarcoma viral oncogene homolog s homeolog (xenopus laevis)) (aka fbj murine osteosarcoma viral oncogene homolog s homeolog)
C: serum response facto... | [G; H] |
<Instruct>: Given the context 'We have isolated cDNA clones encoding serum response factor (SRF), a ubiquitous nuclear protein that binds to the SRE.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [serum response factor; srf]
<Options>: A: srf (homo sapiens) (aka serum response factor)
B: serum response factor (xenopus tropicalis) (aka serum response factor)
C: serum response factor homolog a (glycine max) (aka serum response factor homolog a)
D: srf (sus scrofa) (aka serum response factor)
E: srf-1 ... | [A; A] |
<Instruct>: Given the context 'We have isolated cDNA clones encoding serum response factor (SRF), a ubiquitous nuclear protein that binds to the SRE.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [serum response factor; srf]
<Options>: A: serum response factor homolog b (glycine max) (aka serum response factor homolog b)
B: srf-1 (homo sapiens) (aka spermatogenesis associated 6)
C: serum response factor homolog a (glycine max) (aka serum response factor homolog a)
D: serum response factor (mus muscu... | [H; H] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.