instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [nck5a]
<Options>: A: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
B: nek5 (homo sapiens) (aka nima related kinase 5)
C: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
D: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
E: nck5ai (xenopus tropical... | [D] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: dna-directed rna polymerase iii subunit c53 (saccharomyces cerevisiae s288c) (aka dna-directed rna polymerase iii subunit c53)
B: tcce518 (homo sapiens) (aka transmembrane 4 l six family member 20)
C: c34 (homo sapiens) (aka rna polymerase iii subunit f)
D: mm28 (homo sa... | [O; T; F; T] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c48 (homo sapiens) (aka cdk5 regulatory subunit associated protein 2)
B: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
C: c4a6 (homo sapiens) (aka complement c4a (chido/rodgers blood group))
D: mm28 (homo sapiens) (aka matrix metallopeptidase 28)
E: p35nck5a (ho... | [E; S; A; S] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c82 (homo sapiens) (complement c8 beta chain (homo sapiens)) (aka complement c8 beta chain)
B: c53 (rattus norvegicus) (aka cdk5 regulatory subunit associated protein 3)
C: c4b (homo sapiens) (aka complement c4b (chido/rodgers blood group))
D: nck5ai (xenopus tropicalis)... | [R; R; J; R] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: nck (homo sapiens) (aka nck adaptor protein 1)
B: mm28 (homo sapiens) (aka matrix metallopeptidase 28)
C: c53 (mus musculus) (aka cdk5 regulatory subunit associated protein 3)
D: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
E: nck-a (xenopus tropicalis) (aka nck ada... | [F; S; R; S] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c53 (mus musculus) (aka cdk5 regulatory subunit associated protein 3)
B: c35 (homo sapiens) (aka migration and invasion enhancer 1)
C: c4a (homo sapiens) (aka complement c4a (chido/rodgers blood group))
D: mgc148328 (bos taurus) (aka uncharacterized loc783058)
E: nck (ho... | [H; T; K; T] |
<Instruct>: Given the context 'The three proteins show competitive binding to Nck5a suggesting that they bind at a common site.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a]
<Options>: A: nck1 (homo sapiens) (aka nck adaptor protein 1)
B: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
C: nek5 (homo sapiens) (aka nima related kinase 5)
D: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
E: nck5a (homo sapiens) (aka cyclin depende... | [E] |
<Instruct>: Given the context 'The binding site has been mapped to a region of 26 amino acid residues (residues 145 to 170) at the N-terminal boundary of the kinase activation domain of Nck5a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, on... | <Mentions>: [nck5a]
<Options>: A: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
B: nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: nek5 (homo sapiens) (aka nima related kinase 5)
D: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
E: nck (homo sapiens) (aka nck adaptor protein 1)
... | [B] |
<Instruct>: Given the context 'The binding site has been mapped to a region of 26 amino acid residues (residues 145 to 170) at the N-terminal boundary of the kinase activation domain of Nck5a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, on... | <Mentions>: [nck5a]
<Options>: A: nek5 (homo sapiens) (aka nima related kinase 5)
B: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
C: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
D: nck (homo sapiens) (aka nck adaptor protein 1)
E: None of the above. | [E] |
<Instruct>: Given the context 'This region of Nck5a contains an amphipathic alpha-helix whose hydrophobic face is involved in Cdk5 activation (Chin, K. T., Ohki, S, Tang, D., Cheng, H. C., Wang, J. H. , and Zhang, M. (1999) J. Biol.', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5 (homo sapiens) (aka cyclin dependent kinase 5)
B: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
C: cdk5 (mus musculus) (aka cyclin dependent kinase 5)
D: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
E: cdk5 (xenopus laevis)... | [H; A] |
<Instruct>: Given the context 'This region of Nck5a contains an amphipathic alpha-helix whose hydrophobic face is involved in Cdk5 activation (Chin, K. T., Ohki, S, Tang, D., Cheng, H. C., Wang, J. H. , and Zhang, M. (1999) J. Biol.', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [nck5a; cdk5]
<Options>: A: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
B: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
C: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
D: cdk5ps (homo sapiens) (aka cyclin dependent kinase 5 pse... | [A; J] |
<Instruct>: Given the context 'Several lines of evidence suggest that Nck5a interacts with the binding proteins at the hydrophilic face of the amphipathic alpha-helix.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separ... | <Mentions>: [nck5a]
<Options>: A: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
B: nek5 (homo sapiens) (aka nima related kinase 5)
C: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
D: nckalpha (homo sapiens) (aka nck adaptor protein 1)
E: nck5ai (homo sapiens) (aka cyclin dependen... | [A] |
<Instruct>: Given the context 'First, the Nck5a-(145-170) peptide can bind Cdk5 and Nck5a-binding proteins simultaneously.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5a (drosophila melanogaster) (aka cdk5 activator-like protein)
B: nek5 (homo sapiens) (aka nima related kinase 5)
C: cyclin dependent kinase 5 (homo sapiens) (aka cyclin dependent kinase 5)
D: cdk5ps (homo sapiens) (aka cyclin dependent kinase 5 pseudogene 1)
E: cdk5r1 (xenopu... | [G; C] |
<Instruct>: Given the context 'First, the Nck5a-(145-170) peptide can bind Cdk5 and Nck5a-binding proteins simultaneously.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a; cdk5]
<Options>: A: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
B: nek5 (homo sapiens) (aka nima related kinase 5)
C: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog (xenopus laevis)) (aka cyclin-dependent kinase 5, regula... | [I; J] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: c56 (homo sapiens) (aka interferon induced protein with tetratricopeptide repeats 1)
B: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
C: tcce518 (homo sapiens) (aka transmembrane 4 l six family member 20)
D: cdk5 (homo sapiens) (aka ... | [J; O; D] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: cdk5a (drosophila melanogaster) (aka cdk5 activator-like protein)
B: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
D: cdk5 (xenopus laevis) (aka cyclin-d... | [B; G; J] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: c48 (homo sapiens) (aka cdk5 regulatory subunit associated protein 2)
B: tcce518 (homo sapiens) (aka transmembrane 4 l six family member 20)
C: c56 (homo sapiens) (aka interferon induced protein with tetratricopeptide repeats 1)
D: nck5ai (xenopus tropicalis) (aka cyclin-dep... | [N; A; L] |
<Instruct>: Given the context 'Third, substitution of Glu(157) by glutamine in Nck5a-(145-170) abolishes the peptide's ability to bind to the three Nck5a-binding proteins without diminishing its Cdk5 binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [nck5a; cdk5]
<Options>: A: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
B: nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
D: cdk5 (drosophila melanogaster) (aka cyclin-dependent k... | [B; G] |
<Instruct>: Given the context 'Third, substitution of Glu(157) by glutamine in Nck5a-(145-170) abolishes the peptide's ability to bind to the three Nck5a-binding proteins without diminishing its Cdk5 binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [nck5a; cdk5]
<Options>: A: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
B: cdk5 (drosophila melanogaster) (aka cyclin-dependent kinase 5)
C: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
D: cdk5ps (homo sapiens) (aka cyclin dependent kinase 5 pseudogene 1)
E: nek5 (ho... | [G; J] |
<Instruct>: Given the context 'Third, substitution of Glu(157) by glutamine in Nck5a-(145-170) abolishes the peptide's ability to bind to the three Nck5a-binding proteins without diminishing its Cdk5 binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [nck5a; cdk5]
<Options>: A: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
B: nek5 (homo sapiens) (aka nima related kinase 5)
C: cdk5a (drosophila melanogaster) (aka cdk5 activator-like protein)
D: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
E: nck5a (homo sapiens) (ak... | [E; G] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: colony stimulating factor 3 (granulocyte) (mus musculus) (aka colony stimulating factor 3 (granulocyte))
B: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) ... | [F; O; B; N] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
B: cd34 molecule (homo sapiens) (aka cd34 molecule)
C: colony stimulating factor 1 (h... | [A; B; E; F] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: atypical chemokine receptor 3 (xenopus tropicalis) (aka atypical chemokine receptor 3)
B: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
C: fa... | [T; S; F; Q] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: colony stimulating factor 3 (granulocyte) (mus musculus) (aka colony stimulating factor 3 (granulocyte))
B: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) ... | [G; H; B; S] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: atypical chemokine receptor 3 (ho... | [T; P; F; H] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: interleukin 10 (homo sapiens) (aka interleukin 10)
B: c-x-c motif chemokine receptor 3 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3)
C: ip-10 (homo sapiens) ... | [R; I; I; C] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
B: c-x-c motif chemokine receptor 3 gene 2 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3 gene 2)... | [I; J; J; N] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: mig-6 (homo sapiens) (aka erbb receptor feedback inhibitor 1)
B: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
C: mig-14 (homo sap... | [L; K; K; O] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
B: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
C: mig-14 (homo sapiens) (aka wnt ligand secretion... | [A; R; R; D] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: interleukin 10 (homo sapiens) (aka interleukin 10)
B: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
C: mip2g (homo sapiens) (aka c-x-c motif chemokine ligand 14)
D:... | [I; F; F; G] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: il-10c (homo sapiens) (aka interleukin 19)
B: il-10a (homo sapiens) (aka interleukin 10)
C: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
D: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
E: ld78gamma (homo sapiens)... | [F; H; H] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
B: mip-3a (homo sapiens) (aka c-c motif chemokine ligand 20)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
... | [H; C; C] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: mip-2g (homo sapiens) (aka c-x-c motif chemokine ligand 14)
B: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
C: mip-3 (homo sapiens) (aka c-c motif chemokine ligand 23)
D: il-10a (homo sapiens) (aka interleukin 10)
E: mig10 (homo s... | [G; N; N] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
B: interleukin 10 (homo sapiens) (aka interleukin 10)
C: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
E:... | [C; I; I] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: csf1 (homo sapiens) (aka colony stimulating factor 1)
D: cd34 ... | [L; E; F; F] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: cd344 (homo sapiens) (aka frizzled class receptor 4)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
D: cc-ckr-9 (homo sapiens) (aka c-c m... | [H; R; P; P] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
B: myeloid derived growth factor (homo sapiens) (aka myeloid derived growth factor)
C: csf1 (homo sapiens) (aka colony stimulating factor 1)
D: multi-csf (homo ... | [E; G; F; F] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: colony stimulating factor 3 (granulocyte) (mus musculus) (aka colony stimulating factor 3 (granulocyte))
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: gm-csf (mus musculus) (aka colony stimulating factor 2 (granu... | [O; P; Q; Q] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cd34]
<Options>: A: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
B: cd34 molecule (gallus gallus) (aka cd34 molecule)
C: cd34 (sus scrofa) (aka cd34 molecule)
D: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)
E: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 ... | [E] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cd34]
<Options>: A: cd34 (sus scrofa) (aka cd34 molecule)
B: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
C: cd34 molecule (gallus gallus) (aka cd34 molecule)
D: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)
E: None of the above. | [E] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: c-x-c motif chemokine receptor 3 gene 2 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3 gene 2)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
D: gm-csf (mus musculus) (aka colony stimulating fac... | [N; H; O] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: cd34 (gallus gallus) (aka cd34 molecule)
B: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
C: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
D: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
E: fat4 (homo sapi... | [K; J; L] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
B: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)
C: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
D: c-x3-c motif chemokine receptor 1 (homo ... | [E; F; A] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: il-10c (homo sapiens) (aka interleukin 19)
C: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
D: mig-6 (homo sapiens) (aka erbb receptor feedback inhibitor 1)
E: nectin... | [G; F; K; R] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
B: gip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
C: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
D: cd34 (sus scrofa) (aka cd34 molecule)
E: cd344 (homo... | [B; G; P; Q] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: gip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
D: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
E: il-10c (homo sapiens) (aka in... | [A; D; F; I] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: csf-1 (homo sapiens) (aka colony stimulating factor 1)
B: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: cd34 (gallus gallus) (aka cd34 molecule)
D: cd344 (homo sapiens) (aka frizzled class receptor 4)
E: interleukin 1 family member 10 (homo sa... | [K; F; I; T] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: gip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
C: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
D: rxfpr3 (homo sapiens) (aka relaxin family peptide rece... | [F; A; G] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
B: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
C: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
D: il-10c (homo sapiens) (aka interleukin 19)
E: mig11 (homo s... | [N; F; A] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: ifi10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
C: il-10c (homo sapiens) (aka interleukin 19)
D: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
E: c-x3-c motif chemokine receptor 1 (homo sa... | [I; A; B] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cd34]
<Options>: A: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
B: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
C: fat4 (homo sapiens) (aka fat atypical cadherin 4)
D: cd34 molecule (gallus gallus) (aka cd34 molecule)
E: cd344 (homo sapiens) (aka frizzled class r... | [B] |
<Instruct>: Given the context 'These chemotactic attracted CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd34]
<Options>: A: cd34 molecule (gallus gallus) (aka cd34 molecule)
B: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
D: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)
E: cd34 (homo sapiens) (cd34 molecule (ho... | [E] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: cd34 (sus scrofa) (aka cd34 molecule)
B: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
C: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
D: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
E: mig-14 (homo sapi... | [L; T; M; B] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
B: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
C: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
D: gm-csf (mus musculus) (aka colony stimulating factor... | [F; T; R; N] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: fat4 (homo sapiens) (aka fat atypical cadherin 4)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: gmcsf (homo sapiens) (aka colony stimulating factor 2)
D: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
E: ... | [I; M; C; Q] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
B: csf-1 (homo sapiens) (aka colony stimulating factor 1)
C: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
D: fat4 (homo sapiens) (aka fat atypical cadherin 4)
E: cd34 ... | [H; S; I; O] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: fat4 (homo sapiens) (aka fat atypical cadherin 4)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))... | [H; C; D; P] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
B: cd2f-10 (homo sapiens) (aka slam family member 9)
C: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
D: mig-6 (homo sapiens) (aka erbb receptor feedback inhibitor 1)
E: mig10 (homo sapiens) ... | [G; M; N] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
B: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
C: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
D: cxcr3 (homo sapiens) (aka c-x-c motif chemokine recept... | [D; K; H] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: pla2g10ip (homo sapiens) (aka phospholipase a2 group xi, pseudogene)
B: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
C: il-10a (homo sapiens) (aka interleukin 10)
D: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
E: mig10 (homo sapiens) (aka phos... | [H; N; D] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [chemokine stromal cell-derived factor 1 alpha]
<Options>: A: sdf2 (homo sapiens) (aka stromal cell derived factor 2)
B: sdf1 (homo sapiens) (aka c-x-c motif chemokine ligand 12)
C: sdf-5 (homo sapiens) (aka secreted frizzled related protein 2)
D: mip-1-alpha (homo sapiens) (aka c-c motif chemokine ligand 3... | [B] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: cd49b (homo sapiens) (aka integrin subunit alpha 2)
B: integrin subunit alpha 9 (homo sapiens) (aka integrin subunit alpha 9)
C: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)
D: c-x-c motif chemokine ligand 10 (homo sapiens) (aka c-x-c motif chemok... | [D; K; Q; A] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
B: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
C: cd49a (homo sapiens) (aka integrin subunit alpha 1)
D: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
E: interleukin 1 fa... | [Q; L; C; K] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: glycoprotein ix platelet (homo sapiens) (aka glycoprotein ix platelet)
B: cd41b (homo sapiens) (aka integrin subunit alpha 2b)
C: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
D: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
E: mig9 (homo... | [K; D; R; L] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: glycoprotein ix platelet (homo sapiens) (aka glycoprotein ix platelet)
B: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
C: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
D: il-10c (homo sapiens) (aka interleuk... | [E; H; N; P] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
B: cd42b (homo sapiens) (aka glycoprotein ib platelet subunit alpha)
C: cd49fa (homo sapiens) (aka integrin subunit alpha 6)
D: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
E: cd49e ... | [O; L; P; Q] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gm-csf; cd34]
<Options>: A: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
D: cd340 (homo sapiens) (aka erb-b2 receptor... | [F; C] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gm-csf; cd34]
<Options>: A: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
B: csf-1 (homo sapiens) (aka colony stimulating factor 1)
C: fat4 (homo sapiens) (aka fat atypical cadherin 4)
D: cd34 molecule (gallus gallus) (aka cd34 molecule)
E: cd340 (homo sapiens) (aka erb-b... | [I; J] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gm-csf; cd34]
<Options>: A: cd34 molecule (homo sapiens) (aka cd34 molecule)
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: cd34 (sus scrofa) (aka cd34 molecule)
D: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
E: cd114 (homo sapiens) (aka colony stimulating fact... | [J; A] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
D: colony stimulating factor 3 (homo sapiens) (aka colony s... | [J; P; A; E] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
B: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
C: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
D: multi-csf (homo sapiens) (aka... | [K; C; I; M] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
C: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: il-10c (homo sapiens) (aka interleukin 19)
E: c-x3-c ... | [C; Q; J; T] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: mig-6 (homo sapiens) (aka erbb receptor feedback inhibitor 1)
B: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
C: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
D: il-10c (homo sapiens) (aka interleukin 19)
E... | [Q; J; E; R] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: mig9 (homo sapiens) (aka s100 calcium binding protein p)
B: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
C: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
D: c-c chemokine receptor type ... | [H; Q; P; J] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [cd34]
<Options>: A: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
B: cd34 molecule (gallus gallus) (aka cd34 molecule)
C: cd34 (sus scrofa) (aka cd34 molecule)
D: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
E: nectin-4 (homo sapiens) (aka nectin cell adhesion molec... | [A] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: c-c motif chemokine receptor 3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
D: mig (homo sapiens) (aka c-x-c mo... | [E; J; D] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
B: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
C: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
D: il-10c (homo sapiens) (aka interleukin 19)
E: c-c chemokine receptor type 3 (... | [O; J; F] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: c-x-c motif chemokine receptor 3 gene 2 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3 gene 2)
B: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
C: gip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: mig15... | [B; C; F] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [gm-csf; cd34]
<Options>: A: cd34 (sus scrofa) (aka cd34 molecule)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
D: cd34 (gallus gallus) (aka cd34 molecule)
E: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
... | [F; H] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [gm-csf; cd34]
<Options>: A: csf-1 (homo sapiens) (aka colony stimulating factor 1)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: cd344 (homo sapiens) (aka frizzled class receptor 4)
D: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
E: cd34 (sus scrofa) (a... | [J; G] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [gm-csf; cd34]
<Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: cd34 molecule (homo sapiens) (aka cd34 molecule)
D: csf1 (homo sapiens) (aka colony stimulating factor 1)
E: nectin-4 (homo sapiens) (aka nectin cell a... | [J; C] |
<Instruct>: Given the context 'These processes include transmigration, relocation, differentiation, and maturation of CD34(+) hematopoietic progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicol... | <Mentions>: [cd34]
<Options>: A: cd34 molecule (gallus gallus) (aka cd34 molecule)
B: cd344 (homo sapiens) (aka frizzled class receptor 4)
C: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
D: cd34 molecule (homo sapiens) (aka cd34 molecule)
E: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor... | [D] |
<Instruct>: Given the context 'HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120; gp160]
<Options>: A: envelope glycoprotein c (human alphaherpesvirus 1) (aka envelope glycoprotein c)
B: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
C: nef (human immunodeficiency virus 1) (aka nef)
D: vif (human immunodeficiency virus 1) (aka vif)
E: en... | [B; B] |
<Instruct>: Given the context 'HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120; gp160]
<Options>: A: py160 (homo sapiens) (aka insulin receptor substrate 4)
B: envelope glycoprotein c (human alphaherpesvirus 1) (aka envelope glycoprotein c)
C: envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
D: ... | [C; C] |
<Instruct>: Given the context 'Recently, the alpha-chemokine receptor CXCR4 has been reported to mediate apoptosis in neuronal cells and in CD4(+) and CD8(+) T cells after its binding to HIV-1 envelope proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the s... | <Mentions>: [alpha-chemokine receptor cxcr4]
<Options>: A: x-c motif chemokine receptor 1 (homo sapiens) (aka x-c motif chemokine receptor 1)
B: c-c chemokine receptor type 8 (xenopus tropicalis) (aka c-c chemokine receptor type 8)
C: atypical chemokine receptor 4 (xenopus tropicalis) (aka atypical chemokine receptor 4... | [E] |
<Instruct>: Given the context 'In the current study, it was observed that human umbilical vein endothelial cells (HUVEC) undergo apoptosis after their treatment with the HIV-1 envelope proteins gp120/160.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [gp120/160]
<Options>: A: gp160 (mus musculus) (aka leucyl/cystinyl aminopeptidase)
B: gp120 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 4)
C: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
D: mg-160 (rattus norvegicus) (aka golgi glycoprotein 1)
... | [C] |
<Instruct>: Given the context 'Anti-CXCR4 monoclonal antibody decreased HIV-1 gp120/160-induced apoptosis, suggesting that the CXCR4 chemokine receptor mediates the apoptotic effects of these HIV envelope glycoproteins.', select the correct biomedical concept for each mention using the provided options. Answer by listi... | <Mentions>: [cxcr4; gp120/160]
<Options>: A: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
B: atypical chemokine receptor 4 (xenopus tropicalis) (aka atypical chemokine receptor 4)
C: mg160 (homo sapiens) (aka golgi glycoprotein 1)
D: gp160 (rattus norvegicus) (aka leucyl and cystinyl aminopeptidase... | [J; H] |
<Instruct>: Given the context 'Anti-CXCR4 monoclonal antibody decreased HIV-1 gp120/160-induced apoptosis, suggesting that the CXCR4 chemokine receptor mediates the apoptotic effects of these HIV envelope glycoproteins.', select the correct biomedical concept for each mention using the provided options. Answer by listi... | <Mentions>: [cxcr4; gp120/160]
<Options>: A: envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
B: cc-ckr-4 (homo sapiens) (aka c-c motif chemokine receptor 4)
C: c-c chemokine receptor type 8 (xenopus tropicalis) (aka c-c chemokine recep... | [I; A] |
<Instruct>: Given the context 'Further studies revealed that caspases play an important role in this process because the pretreatment of cells with a general caspase enzyme inhibitor decreased the extent of HUVEC apoptosis induced by gp120/160.', select the correct biomedical concept for each mention using the provided... | <Mentions>: [gp120/160]
<Options>: A: gp160 (homo sapiens) (aka glutamyl aminopeptidase)
B: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
C: gp160 (mus musculus) (aka leucyl/cystinyl aminopeptidase)
D: gp120 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 4)
E: ... | [B] |
<Instruct>: Given the context 'In addition, it was found that caspase-3 was activated on HIV-1 gp120/160 treatment of these cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caspase-3; gp120/160]
<Options>: A: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
B: casp3 (homo sapiens) (aka caspase 3)
C: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
D: casp-7 (homo sapiens) (aka caspase 7)
E: caspase-3 (drosophila melano... | [B; A] |
<Instruct>: Given the context 'In addition, it was found that caspase-3 was activated on HIV-1 gp120/160 treatment of these cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caspase-3; gp120/160]
<Options>: A: gp120 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 4)
B: ich-3 (homo sapiens) (aka caspase 5)
C: envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
D: caspase-3 (mus muscul... | [G; C] |
<Instruct>: Given the context 'It was also observed that gp120/160 treatment slightly increased the expression of the pro-apoptotic molecule Bax.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120/160; bax]
<Options>: A: bak-like (homo sapiens) (aka bcl2 antagonist/killer 1)
B: mg-160 (homo sapiens) (aka golgi glycoprotein 1)
C: bax (escherichia coli str. k-12 substr. mg1655) (aka putative glycoside hydrolase bax)
D: envelope surface glycoprotein gp160, precursor (human immunodeficiency virus ... | [D; G] |
<Instruct>: Given the context 'It was also observed that gp120/160 treatment slightly increased the expression of the pro-apoptotic molecule Bax.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120/160; bax]
<Options>: A: bax (homo sapiens) (aka bcl2 associated x, apoptosis regulator)
B: bak-like (homo sapiens) (aka bcl2 antagonist/killer 1)
C: hhv5wtgp160 (human betaherpesvirus 5) (aka membrane protein us30)
D: bax (escherichia coli str. k-12 substr. mg1655) (aka putative glycoside hydrolase b... | [J; A] |
<Instruct>: Given the context 'It was also observed that gp120/160 treatment slightly increased the expression of the pro-apoptotic molecule Bax.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gp120/160; bax]
<Options>: A: env (human immunodeficiency virus 1) (aka envelope surface glycoprotein gp160, precursor)
B: bax (escherichia coli str. k-12 substr. mg1655) (aka putative glycoside hydrolase bax)
C: gp160 (homo sapiens) (aka glutamyl aminopeptidase)
D: hhv5wtgp160 (human betaherpesvirus 5) (a... | [A; H] |
<Instruct>: Given the context 'These results suggest that HIV-1 envelope glycoproteins can disrupt endothelial integrity through the interaction with CXCR4, thereby facilitating virus transit out of the bloodstream and contributing to the vascular injury syndromes seen in acquired immunodeficiency syndrome.', select th... | <Mentions>: [cxcr4]
<Options>: A: atypical chemokine receptor 4 (xenopus tropicalis) (aka atypical chemokine receptor 4)
B: c-c motif chemokine receptor 4 (homo sapiens) (aka c-c motif chemokine receptor 4)
C: c-x-c motif chemokine receptor 4 (homo sapiens) (aka c-x-c motif chemokine receptor 4)
D: chemokine (c motif) ... | [C] |
<Instruct>: Given the context 'Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome).
', select the correct biomedical concept for each mention using the provided options. Answer b... | <Mentions>: [collagen xviii]
<Options>: A: collagen type xviii alpha 1 chain (homo sapiens) (aka collagen type xviii alpha 1 chain)
B: collagen, type xviii, alpha 1 (sus scrofa) (aka collagen, type xviii, alpha 1)
C: collagen type xxviii alpha 1 chain (homo sapiens) (aka collagen type xxviii alpha 1 chain)
D: collagen ... | [A] |
<Instruct>: Given the context 'We reconstructed the haplotypes of this family with ten additional markers (five were novel) and narrowed the candidate interval to a region of < 245 kb, which contains 24 expressed sequence tags, the KIAA0958 gene and the 5' end of the COL18A1 gene.', select the correct biomedical concep... | <Mentions>: [kiaa0958; col18a1]
<Options>: A: c17orf58 homolog (gallus gallus) (aka c17orf58 homolog)
B: kiaa0759l (homo sapiens) (aka angel homolog 2)
C: c11orf58 homolog (gallus gallus) (aka c11orf58 homolog)
D: col18a1 (homo sapiens) (aka collagen type xviii alpha 1 chain)
E: kiaa0859 (homo sapiens) (aka methyltrans... | [K; D] |
<Instruct>: Given the context 'We reconstructed the haplotypes of this family with ten additional markers (five were novel) and narrowed the candidate interval to a region of < 245 kb, which contains 24 expressed sequence tags, the KIAA0958 gene and the 5' end of the COL18A1 gene.', select the correct biomedical concep... | <Mentions>: [kiaa0958; col18a1]
<Options>: A: col18a1 (danio rerio) (aka collagen type xviii alpha 1 chain a)
B: chromosome 4 c11orf58 homolog (xenopus tropicalis) (aka chromosome 4 c11orf58 homolog)
C: chromosome 3 c8orf58 homolog (xenopus tropicalis) (aka chromosome 3 c8orf58 homolog)
D: col18a1 (mus musculus) (aka c... | [K; E] |
<Instruct>: Given the context 'We identified a homozygous mutation at the AG consensus acceptor splice site of COL18A1 intron 1 exclusively among the 12 KS patients, which was not found among 140 control chromosomes.', select the correct biomedical concept for each mention using the provided options. Answer by listing ... | <Mentions>: [col18a1]
<Options>: A: col18a1 (danio rerio) (aka collagen type xviii alpha 1 chain a)
B: col18a1 (rattus norvegicus) (aka collagen type xviii alpha 1 chain)
C: col18a1 (homo sapiens) (aka collagen type xviii alpha 1 chain)
D: col18a1 (bos taurus) (aka collagen type xviii alpha 1 chain)
E: col18a1 (xenopus... | [C] |
<Instruct>: Given the context 'This mutation predicts the creation of a stop codon in exon 4 and therefore the truncation of the alpha1(XVIII) collagen short form, which was expressed in human adult retina.', select the correct biomedical concept for each mention using the provided options. Answer by listing the select... | <Mentions>: [alpha1(xviii) collagen]
<Options>: A: collagen type xviii alpha 1 (xenopus tropicalis) (aka collagen type xviii alpha 1)
B: collagen, type xxviii, alpha 1 (xenopus tropicalis) (aka collagen, type xxviii, alpha 1)
C: collagen type xviii alpha 1 chain (sus scrofa) (aka collagen type xviii alpha 1 chain)
D: c... | [D] |
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