instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'We found that ataxin-3 interacts with two human homologs of the yeast DNA repair protein RAD23, HHR23A and HHR23B.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ataxin-3; rad23; hhr23a; hhr23b]
<Options>: A: ataxin 3 (xenopus tropicalis) (aka ataxin 3)
B: ataxin-3 homolog (caenorhabditis elegans) (aka ataxin-3 homolog)
C: nr3b2 (homo sapiens) (aka estrogen related receptor beta)
D: ataxin 3 (mus musculus) (aka ataxin 3)
E: hhr23b (homo sapiens) (aka rad23 nucleoti... | [Q; R; H; E] |
<Instruct>: Given the context 'We found that ataxin-3 interacts with two human homologs of the yeast DNA repair protein RAD23, HHR23A and HHR23B.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ataxin-3; rad23; hhr23a; hhr23b]
<Options>: A: hhr21 (homo sapiens) (aka rad21 cohesin complex component)
B: rad23a (homo sapiens) (aka rad23 nucleotide excision repair protein a)
C: dhr23 (drosophila melanogaster) (rad23 (drosophila melanogaster)) (aka rad23)
D: atxn3 (homo sapiens) (aka ataxin 3)
E: atax... | [D; M; B; F] |
<Instruct>: Given the context 'Furthermore, we confirmed that ataxin-3 interacts with the -ubiquitin-like domain at the N-terminus of the HHR23 proteins, which is important for nucleotide excision repair; however, ataxin-3 does not interact with -ubiquitin, implying that ataxin-3 might be functionally associated with t... | <Mentions>: [ataxin-3]
<Options>: A: ataxin 7 like 3 (homo sapiens) (aka ataxin 7 like 3)
B: sca3 (homo sapiens) (aka ataxin 3)
C: ataxin 3 (mus musculus) (aka ataxin 3)
D: ataxin 3 (sus scrofa) (aka ataxin 3)
E: ataxin-3 homolog (caenorhabditis elegans) (aka ataxin-3 homolog)
F: None of the above. | [B] |
<Instruct>: Given the context 'The normal and mutant ataxin-3 proteins show no difference in their ability to bind to the HHR23 proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ataxin-3]
<Options>: A: ataxin 7 like 3 (homo sapiens) (aka ataxin 7 like 3)
B: ataxin-3 (mus musculus) (aka ataxin 3)
C: ataxin 3 (xenopus tropicalis) (aka ataxin 3)
D: atxn3 (homo sapiens) (aka ataxin 3)
E: ataxin 3 (sus scrofa) (aka ataxin 3)
F: None of the above. | [D] |
<Instruct>: Given the context 'However, in 293 cells HHR23A is recruited to intranuclear inclusions formed by the mutant ataxin-3 through its interaction with ataxin-3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, sepa... | <Mentions>: [hhr23a; ataxin-3]
<Options>: A: rad23a (homo sapiens) (aka rad23 nucleotide excision repair protein a)
B: hhr21 (homo sapiens) (aka rad21 cohesin complex component)
C: ataxin-3 (mus musculus) (aka ataxin 3)
D: atx3 (homo sapiens) (aka ataxin 3)
E: hh23 (homo sapiens) (aka luteinizing hormone subunit beta)
... | [A; D] |
<Instruct>: Given the context 'However, in 293 cells HHR23A is recruited to intranuclear inclusions formed by the mutant ataxin-3 through its interaction with ataxin-3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, sepa... | <Mentions>: [hhr23a; ataxin-3]
<Options>: A: rad23 nucleotide excision repair protein a (homo sapiens) (aka rad23 nucleotide excision repair protein a)
B: hhr21 (homo sapiens) (aka rad21 cohesin complex component)
C: hhr6a (homo sapiens) (aka ubiquitin conjugating enzyme e2 a)
D: hh23 (homo sapiens) (aka luteinizing ho... | [A; I] |
<Instruct>: Given the context 'However, in 293 cells HHR23A is recruited to intranuclear inclusions formed by the mutant ataxin-3 through its interaction with ataxin-3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, sepa... | <Mentions>: [hhr23a; ataxin-3]
<Options>: A: ataxin-3 homolog (caenorhabditis elegans) (aka ataxin-3 homolog)
B: hr23b (homo sapiens) (aka rad23 nucleotide excision repair protein b)
C: ataxin 3 (sus scrofa) (aka ataxin 3)
D: hhr6a (homo sapiens) (aka ubiquitin conjugating enzyme e2 a)
E: hh23 (homo sapiens) (aka lutei... | [J; F] |
<Instruct>: Given the context 'These results suggest that this interaction is associated with the normal function of ataxin-3 and that some functional abnormality of the HHR23 proteins might exist in MJD.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected... | <Mentions>: [ataxin-3]
<Options>: A: ataxin 3 (xenopus tropicalis) (aka ataxin 3)
B: ataxin 7 like 3 (homo sapiens) (aka ataxin 7 like 3)
C: ataxin 3 (sus scrofa) (aka ataxin 3)
D: ataxin 3 (mus musculus) (aka ataxin 3)
E: ataxin 3 (homo sapiens) (aka ataxin 3)
F: None of the above. | [E] |
<Instruct>: Given the context 'Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells.
X-linked retinoschisis is characterized by microcystic-like changes of the macular region and schisis within the inner retinal layers, leading to visual... | <Mentions>: [retinoschisin; x-linked retinoschisis protein; x-linked retinoschisis]
<Options>: A: retinal dystrophy, x-linked, gardener-hardcastle type (homo sapiens) (aka retinal dystrophy, x-linked, gardener-hardcastle type)
B: retinoschisin 1 (xenopus tropicalis) (aka retinoschisin 1)
C: retinoschisin 1 (rattus norv... | [D; D; D] |
<Instruct>: Given the context 'Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells.
X-linked retinoschisis is characterized by microcystic-like changes of the macular region and schisis within the inner retinal layers, leading to visual... | <Mentions>: [retinoschisin; x-linked retinoschisis protein; x-linked retinoschisis]
<Options>: A: retinoschisin 1 (homo sapiens) (aka retinoschisin 1)
B: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
C: rs1 (mus musculus) (retinoschisis (x-linked, juvenile) 1 (human) (mus musculus)) (aka retinoschisis (x-linked, j... | [A; A; A] |
<Instruct>: Given the context 'Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells.
X-linked retinoschisis is characterized by microcystic-like changes of the macular region and schisis within the inner retinal layers, leading to visual... | <Mentions>: [retinoschisin; x-linked retinoschisis protein; x-linked retinoschisis]
<Options>: A: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
B: retinoschisin 1 (homo sapiens) (aka retinoschisin 1)
C: retinal dystrophy, x-linked, gardener-hardcastle type (homo sapiens) (aka retinal dyst... | [B; B; B] |
<Instruct>: Given the context 'Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells.
X-linked retinoschisis is characterized by microcystic-like changes of the macular region and schisis within the inner retinal layers, leading to visual... | <Mentions>: [retinoschisin; x-linked retinoschisis protein; x-linked retinoschisis]
<Options>: A: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
B: retinoschisin 1 (xenopus tropicalis) (aka retinoschisin 1)
C: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
D: retinoschisin 1 l homeolog... | [J; J; J] |
<Instruct>: Given the context 'Many missense and protein-truncating mutations of the causative gene RS1 have now been identified and are thought to be inactivating.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separate... | <Mentions>: [rs1]
<Options>: A: rsrc1 (homo sapiens) (aka arginine and serine rich coiled-coil 1)
B: rs1 (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
C: rsrp1 (homo sapiens) (aka arginine and serine rich protein 1)
D: rsg1 (homo sapiens) (aka ciliogenesis and planar polarity effector complex su... | [B] |
<Instruct>: Given the context 'RS1 encodes a 224 amino acid protein, retinoschisin, which contains a discoidin domain but is of unknown function.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rs1; retinoschisin]
<Options>: A: rsrp1 (homo sapiens) (aka arginine and serine rich protein 1)
B: retinoschisin 1 (gallus gallus) (aka retinoschisin 1)
C: retinoschisin 1 (xenopus tropicalis) (aka retinoschisin 1)
D: rs1 (homo sapiens) (regulator of solute carriers 1 (homo sapiens)) (aka regulator of solu... | [E; E] |
<Instruct>: Given the context 'RS1 encodes a 224 amino acid protein, retinoschisin, which contains a discoidin domain but is of unknown function.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rs1; retinoschisin]
<Options>: A: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
B: rs1 (human alphaherpesvirus 1) (transcriptional regulator icp4 (human alphaherpesvirus 1)) (aka transcriptional regulator icp4)
C: rsrp1 (homo sapiens) (aka arginine and serine rich protein 1)
D: retinoschisin 1 s homeo... | [I; I] |
<Instruct>: Given the context 'We have generated a polyclonal antibody against a peptide from a unique region within retinoschisin, which detects a protein of approximately 28 kDa in retinal samples reduced with dithiothreitol, but multimers sized >40 kDa under non-reducing conditions.', select the correct biomedical c... | <Mentions>: [retinoschisin]
<Options>: A: retinoschisin 1 (sus scrofa) (aka retinoschisin 1)
B: retinoschisin 1 (homo sapiens) (aka retinoschisin 1)
C: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
D: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
E: retinoschisin 1a (danio rerio) (ak... | [B] |
<Instruct>: Given the context 'A screen of human tissues with this antibody reveals retinoschisin to be retina specific and the antibody detects a protein of similar size in bovine and murine retinae.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opt... | <Mentions>: [retinoschisin]
<Options>: A: retinoschisin 1 (rattus norvegicus) (aka retinoschisin 1)
B: retinoschisin 1a (danio rerio) (aka retinoschisin 1a)
C: retinoschisin 1 (sus scrofa) (aka retinoschisin 1)
D: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
E: retinoschisin 1 (homo sapiens) (aka retinoschisin 1)... | [E] |
<Instruct>: Given the context 'We investigated the expression pattern in the retina of both RS1 mRNA (using in situ hybridization with riboprobes) and retinoschisin (using immunohistochemistry).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, ... | <Mentions>: [rs1; retinoschisin]
<Options>: A: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
B: rs1 (homo sapiens) (regulator of solute carriers 1 (homo sapiens)) (aka regulator of solute carriers 1)
C: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
D: retinoschisin 1a (danio rerio) (... | [F; F] |
<Instruct>: Given the context 'We investigated the expression pattern in the retina of both RS1 mRNA (using in situ hybridization with riboprobes) and retinoschisin (using immunohistochemistry).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, ... | <Mentions>: [rs1; retinoschisin]
<Options>: A: retinoschisin 1a (danio rerio) (aka retinoschisin 1a)
B: rsf1 (homo sapiens) (aka remodeling and spacing factor 1)
C: retinoschisin 1 (xenopus tropicalis) (aka retinoschisin 1)
D: rs (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
E: rsrp1 (homo sapie... | [D; D] |
<Instruct>: Given the context 'The antisense riboprobe detected RS1 mRNA only in the photoreceptor layer but the protein product of the gene was present both in the photoreceptors and within the inner portions of the retina.', select the correct biomedical concept for each mention using the provided options. Answer by ... | <Mentions>: [rs1]
<Options>: A: rsrp1 (homo sapiens) (aka arginine and serine rich protein 1)
B: rs1 (human alphaherpesvirus 1) (transcriptional regulator icp4 (human alphaherpesvirus 1)) (aka transcriptional regulator icp4)
C: rs1 (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
D: rsrc1 (homo sap... | [C] |
<Instruct>: Given the context 'Furthermore, differentiated retinoblastoma cells (Weri-Rb1 cells) were found to express RS1 mRNA and to release retinoschisin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [rs1; retinoschisin]
<Options>: A: retinoschisin 1a (danio rerio) (aka retinoschisin 1a)
B: rsg1 (homo sapiens) (aka ciliogenesis and planar polarity effector complex subunit 2)
C: rsf1 (homo sapiens) (aka remodeling and spacing factor 1)
D: rsts1 (homo sapiens) (aka creb binding lysine acetyltransferase)
E... | [F; F] |
<Instruct>: Given the context 'Furthermore, differentiated retinoblastoma cells (Weri-Rb1 cells) were found to express RS1 mRNA and to release retinoschisin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [rs1; retinoschisin]
<Options>: A: retinoschisin 1 (xenopus tropicalis) (aka retinoschisin 1)
B: rs (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
C: rs1 (human alphaherpesvirus 1) (transcriptional regulator icp4 (human alphaherpesvirus 1)) (aka transcriptional regulator icp4)
D: rsg1... | [B; B] |
<Instruct>: Given the context 'These results suggest that retinoschisin is released by photo-receptors and has functions within the inner retinal layers.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semico... | <Mentions>: [retinoschisin]
<Options>: A: retinoschisin 1 (bos taurus) (aka retinoschisin 1)
B: rs1 (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
C: retinoschisin 1a (danio rerio) (aka retinoschisin 1a)
D: retinoschisin 1 s homeolog (xenopus laevis) (aka retinoschisin 1 s homeolog)
E: retinoschi... | [B] |
<Instruct>: Given the context 'Thus, X-linked retinoschisis is caused by abnormalities in a putative secreted photoreceptor protein and is the first example of a secreted photo-receptor protein associated with a retinal dystrophy.', select the correct biomedical concept for each mention using the provided options. Answ... | <Mentions>: [x-linked retinoschisis]
<Options>: A: rs1 (homo sapiens) (retinoschisin 1 (homo sapiens)) (aka retinoschisin 1)
B: retinoschisis (x-linked, juvenile) 1 (human) (mus musculus) (aka retinoschisis (x-linked, juvenile) 1 (human))
C: x-linked retinitis pigmentosa gtpase regulator homolog (caenorhabditis elegans... | [A] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [neuronal cdk5 activator; cyclin-dependent protein kinase 5; cdk5]
<Options>: A: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog (xenopus laevis)) (aka cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog)
B: cdk5a (drosophila melanogaster) (ak... | [M; I; I] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [neuronal cdk5 activator; cyclin-dependent protein kinase 5; cdk5]
<Options>: A: cyclin-dependent kinase 5 (drosophila melanogaster) (aka cyclin-dependent kinase 5)
B: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: cdk5 (drosophila melanogaster) (aka cyclin-dependent kinase ... | [B; G; G] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [neuronal cdk5 activator; cyclin-dependent protein kinase 5; cdk5]
<Options>: A: cyclin dependent kinase like 5 (xenopus tropicalis) (aka cyclin dependent kinase like 5)
B: cdk5p1 (homo sapiens) (aka cyclin dependent kinase 5 pseudogene 1)
C: cyclin-dependent-like kinase 5 (caenorhabditis elegans) (aka cycl... | [M; H; H] |
<Instruct>: Given the context 'Identification of a common protein association region in the neuronal Cdk5 activator.
Cyclin-dependent protein kinase 5 (Cdk5) depends on the association with neuronal Cdk5 activator (Nck5a) for kinase activity.', select the correct biomedical concept for each mention using the provided o... | <Mentions>: [nck5a]
<Options>: A: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
B: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
C: nck1 (homo sapiens) (aka nck adaptor protein 1)
D: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
E: nck-a (xenopus tropicali... | [A] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: dna-directed rna polymerase iii subunit c53 (saccharomyces cerevisiae s288c) (aka dna-directed rna polymerase iii subunit c53)
B: nek5 (homo sapiens) (aka nima related kinase 5)
C: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
D: c35 (homo sa... | [Q; T; G; T] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c4b2 (homo sapiens) (aka complement c4b (chido/rodgers blood group))
B: c4a (homo sapiens) (aka complement c4a (chido/rodgers blood group))
C: c53a5.13 (caenorhabditis elegans) (aka fibronectin type-iii domain-containing protein)
D: c4a4 (homo sapiens) (aka complement c4... | [R; T; I; T] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c48 (homo sapiens) (aka cdk5 regulatory subunit associated protein 2)
B: c82 (homo sapiens) (complement c8 beta chain (homo sapiens)) (aka complement c8 beta chain)
C: nckalpha (homo sapiens) (aka nck adaptor protein 1)
D: complement c4a (rodgers blood group)-like (homo ... | [M; S; A; S] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c35a5.13 (caenorhabditis elegans) (aka ncrna)
B: nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: c4a6 (homo sapiens) (aka complement c4a (chido/rodgers blood group))
D: c53 (rattus norvegicus) (aka cdk5 regulatory subunit associated protein 3... | [B; R; R; R] |
<Instruct>: Given the context 'A variety of cellular proteins have been shown to undergo high affinity association with Nck5a, including three novel proteins, C42, C48, and C53 found by a yeast two-hybrid screen (Ching, Y. P., Qi, Z., and Wang, J. H. (2000)', select the correct biomedical concept for each mention using... | <Mentions>: [nck5a; c42; c48; c53]
<Options>: A: c42 (xenopus tropicalis) (aka complement c4a (rodgers blood group))
B: complement c4a (rodgers blood group)-like (homo sapiens) (aka complement c4a (rodgers blood group)-like)
C: c35 (homo sapiens) (aka migration and invasion enhancer 1)
D: c4a6 (homo sapiens) (aka compl... | [G; R; O; R] |
<Instruct>: Given the context 'The three proteins show competitive binding to Nck5a suggesting that they bind at a common site.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a]
<Options>: A: nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
B: nckalpha (homo sapiens) (aka nck adaptor protein 1)
C: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
D: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
E: nek5 (homo sapiens) (aka nima related kinas... | [A] |
<Instruct>: Given the context 'The binding site has been mapped to a region of 26 amino acid residues (residues 145 to 170) at the N-terminal boundary of the kinase activation domain of Nck5a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, on... | <Mentions>: [nck5a]
<Options>: A: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
B: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
C: nek5 (homo sapiens) (aka nima related kinase 5)
D: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
E: p35nck5a (homo sapiens) (aka cycl... | [E] |
<Instruct>: Given the context 'This region of Nck5a contains an amphipathic alpha-helix whose hydrophobic face is involved in Cdk5 activation (Chin, K. T., Ohki, S, Tang, D., Cheng, H. C., Wang, J. H. , and Zhang, M. (1999) J. Biol.', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [nck5a; cdk5]
<Options>: A: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
B: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
C: cyclin dependent kinase 5 (homo sapiens) (aka cyclin dependent kinase 5)
D: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit... | [J; C] |
<Instruct>: Given the context 'This region of Nck5a contains an amphipathic alpha-helix whose hydrophobic face is involved in Cdk5 activation (Chin, K. T., Ohki, S, Tang, D., Cheng, H. C., Wang, J. H. , and Zhang, M. (1999) J. Biol.', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [nck5a; cdk5]
<Options>: A: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
B: cdk5r (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: cdk5a (drosophila melanogaster) (aka cdk5 activator-like protein)
D: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subun... | [F; I] |
<Instruct>: Given the context 'This region of Nck5a contains an amphipathic alpha-helix whose hydrophobic face is involved in Cdk5 activation (Chin, K. T., Ohki, S, Tang, D., Cheng, H. C., Wang, J. H. , and Zhang, M. (1999) J. Biol.', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5a (drosophila melanogaster) (aka cdk5 activator-like protein)
B: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
C: cdk5 (xenopus laevis) (aka cyclin-dependent kinase 5 l homeolog)
D: nek5 (homo sapiens) (aka nima related kinase 5)
E: p35nck5a (homo sapiens) (aka cycli... | [E; J] |
<Instruct>: Given the context 'Several lines of evidence suggest that Nck5a interacts with the binding proteins at the hydrophilic face of the amphipathic alpha-helix.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separ... | <Mentions>: [nck5a]
<Options>: A: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
B: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
C: nek5 (homo sapiens) (aka nima related kinase 5)
D: p35nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
E: nckalpha (h... | [D] |
<Instruct>: Given the context 'First, the Nck5a-(145-170) peptide can bind Cdk5 and Nck5a-binding proteins simultaneously.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog (xenopus laevis)) (aka cyclin-dependent kinase 5, regulatory subunit 1 (p35) like s homeolog)
B: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
C: cdk5ps (ho... | [H; D] |
<Instruct>: Given the context 'First, the Nck5a-(145-170) peptide can bind Cdk5 and Nck5a-binding proteins simultaneously.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [nck5a; cdk5]
<Options>: A: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
B: cyclin dependent kinase 5 (homo sapiens) (aka cyclin dependent kinase 5)
C: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
D: cdk5a (drosophila melanogaster) (ak... | [G; B] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
B: nck5ai (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 2)
C: c4a6 (homo sapiens) (aka complement c4a (chido/rodgers blood group))
D: c48 (homo sapiens) (aka cdk5 regulatory subunit ... | [A; D; N] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: cdk5ps (homo sapiens) (aka cyclin dependent kinase 5 pseudogene 1)
B: cdk5 (mus musculus) (aka cyclin dependent kinase 5)
C: nck5ai (xenopus tropicalis) (aka cyclin-dependent kinase 5, regulatory subunit 2 (p39))
D: cdk5r1 (xenopus laevis) (cyclin-dependent kinase 5, regulat... | [K; J; E] |
<Instruct>: Given the context 'Second, the association of Nck5a-(145-170) to C48 can be markedly reduced by high ionic strength whereas the interaction between Nck5a and Cdk5 is not affected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one... | <Mentions>: [nck5a; c48; cdk5]
<Options>: A: c34 (homo sapiens) (aka rna polymerase iii subunit f)
B: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
C: c48 (homo sapiens) (aka cdk5 regulatory subunit associated protein 2)
D: nck5a (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
E: nck5ai (xenopus... | [D; C; M] |
<Instruct>: Given the context 'Third, substitution of Glu(157) by glutamine in Nck5a-(145-170) abolishes the peptide's ability to bind to the three Nck5a-binding proteins without diminishing its Cdk5 binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [nck5a; cdk5]
<Options>: A: cdk5 (xenopus laevis) (aka cyclin-dependent kinase 5 l homeolog)
B: cdk5 (homo sapiens) (aka cyclin dependent kinase 5)
C: nck-a (xenopus tropicalis) (aka nck adaptor protein 1)
D: cdk5ps (homo sapiens) (aka cyclin dependent kinase 5 pseudogene 1)
E: cdk5 (drosophila melanogaster... | [I; B] |
<Instruct>: Given the context 'Third, substitution of Glu(157) by glutamine in Nck5a-(145-170) abolishes the peptide's ability to bind to the three Nck5a-binding proteins without diminishing its Cdk5 binding activity.', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [nck5a; cdk5]
<Options>: A: cyclin dependent kinase 5 (homo sapiens) (aka cyclin dependent kinase 5)
B: cdk5r (homo sapiens) (aka cyclin dependent kinase 5 regulatory subunit 1)
C: cb1k5 (homo sapiens) (aka cannabinoid receptor 1)
D: nckalpha (homo sapiens) (aka nck adaptor protein 1)
E: nck5a (homo sapiens... | [E; A] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
B: colony stimulating factor 3 (granulocyte) (mus musculus) (aka colony stimulating factor 3 (granulocyte))
C: ... | [P; M; H; Q] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
B: csf-1 (homo sapiens) (aka colony stimulating factor 1)
C: csf (homo sapiens) (colony stimulating factor 2 (homo sapi... | [L; I; C; Q] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 mo... | [H; C; Q; D] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
B: csf1 (homo sapiens) (aka colony stimulating factor 1)
C: chemokine (c-c motif) r... | [T; D; G; I] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [cxc chemokine receptor 3; cd34; granulocyte-macrophage colony-stimulating factor; interferon gamma-inducible protein 10]
<Options>: A: colony stimulating factor 3 (granulocyte) (mus musculus) (aka colony stimulating factor 3 (granulocyte))
B: cd34 molecule (gallus gallus) (aka cd34 molecule)
C: interleukin... | [J; N; Q; S] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: mip-1d (homo sapiens) (aka c-c motif chemokine ligand 15)
B: chemokine (c-c motif) receptor 3 (xenopus tropicalis) (aka chemokine (c-c motif) receptor 3)
C: ip-10 (homo sa... | [J; O; O; F] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: cc-ckr-3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: interleukin 10 (homo sapiens) (aka interleukin 10)
C: interferon gamma (homo sapiens) (aka interferon gamma... | [H; D; D; E] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
B: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
C: interferon gamma (homo... | [A; B; B; O] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: interferon gamma (homo sapiens) (aka interferon gamma)
B: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
C: mip-2g (homo sapiens) (aka c-x-c motif chemokine li... | [K; Q; Q; H] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [monokine induced by interferon gamma; cxc chemokine receptor 3; cxcr3; interferon gamma (ifn-gamma)-inducible protein 10]
<Options>: A: c-x-c motif chemokine receptor 3 gene 2 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3 gene 2)
B: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
C: c-... | [B; Q; Q; J] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: il-10c (homo sapiens) (aka interleukin 19)
B: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
C: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
D: mip-1d (homo sapiens) (aka c-c motif chemokine ligand 15)
E: mig15 (homo sapi... | [K; B; B] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: midkine (homo sapiens) (aka midkine)
B: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
C: mip-2g (homo sapiens) (aka c-x-c motif chemokine ligand 14)
D: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
E: mig-6 (homo sapiens) ... | [H; G; G] |
<Instruct>: Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC c... | <Mentions>: [gamma ip-10; monokine induced by ifn-gamma; mig]
<Options>: A: c-x-c motif chemokine ligand 10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: ld78gamma (homo sapiens) (aka c-c motif chemokine ligand 3 pseudogene 1)
C: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
D: mip-3a (homo sap... | [A; H; H] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: cd34 (gallus gallus) (aka cd34 molecule)
B: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
C: colony stimulating factor 3 (granulocyte) (mus musculus) (aka colony stimulating factor ... | [B; I; D; D] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
B: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: c-c chemokine receptor type 3 (xenopus tropic... | [K; L; E; E] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
B: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
C: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x... | [C; E; A; A] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cxcr3; cd34; granulocyte-macrophage colony-stimulating factor; gm-csf]
<Options>: A: multi-csf (homo sapiens) (aka interleukin 3)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
D: colony stimulating f... | [O; C; D; D] |
<Instruct>: Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', select the correct biomedical concept for each m... | <Mentions>: [cd34]
<Options>: A: cd114 (homo sapiens) (aka colony stimulating factor 3 receptor)
B: cd34 (gallus gallus) (aka cd34 molecule)
C: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
D: cd34 (sus scrofa) (aka cd34 molecule)
E: fat4 (homo sapiens) (aka fat atypical cadherin 4)
F: None of ... | [C] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: c-c motif chemokine receptor 3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: multi-csf (homo sapiens) (aka interleukin 3)
C: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
D: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine recep... | [L; M; G] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: c-x-c motif chemokine receptor 3 gene 2 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3 gene 2)
B: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: colony stimulating facto... | [F; M; I] |
<Instruct>: Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', select the correct biomedical concept for each men... | <Mentions>: [cd34; cxcr3; gm-csf]
<Options>: A: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
B: csf-1 (homo sapiens) (aka colony stimulating factor 1)
C: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
D: cd34 (gallus gallus) (aka cd34 molecule)
E: cxcr3 (homo sapiens) (aka ... | [M; E; O] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: mig10 (homo sapiens) (aka phosphoglycerate kinase 1)
B: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
C: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
D: interferon alpha 10 (homo sapiens) (aka inter... | [T; G; I; L] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interleukin 10 (homo sapiens) (aka interleukin 10)
B: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
C: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
D: cd34 (sus scrofa) (aka cd34 molecule)
E: gmcsf (homo sapiens) ... | [M; G; E; N] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: csf2 (homo sapiens) (aka colony stimulating factor 2)
B: mig-6 (mus musculus) (aka erbb receptor feedback inhibitor 1)
C: cd34 molecule (homo sapiens) (aka cd34 molecule)
D: csf1 (homo sapiens) (aka colony stimulating factor 1)
E: mig-14 (homo sapiens) (aka wnt... | [I; R; A; C] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: ifi10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: gmcsf (homo sapiens) (aka colony stimulating factor 2)
C: interleukin 10 (homo sapiens) (aka interleukin 10)
D: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
E: cd1... | [A; T; B; F] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: il-10c (homo sapiens) (aka interleukin 19)
B: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
C: mig (mus musculus) (aka c-x-c motif chemokine ligand 9)
D: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family m... | [F; N; L] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
B: c-x-c motif chemokine receptor 3 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3)
C: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
D: c-c motif chemokine rece... | [J; H; M] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
B: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
C: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
D: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine r... | [K; M; G] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
B: mig-6 (homo sapiens) (aka erbb receptor feedback inhibitor 1)
C: interleukin 10 (homo sapiens) (aka interleukin 10)
D: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
E: ip-10 (mus musculus) (ak... | [J; O; I] |
<Instruct>: Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', select the correct biomedical concept for each mention u... | <Mentions>: [cd34]
<Options>: A: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
B: cd34 (gallus gallus) (aka cd34 molecule)
C: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
D: fat4 (homo sapiens) (aka fat atypical cadherin 4)
E: cd34 molecule (homo sapiens) (aka cd34 molecule)
F: None of t... | [E] |
<Instruct>: Given the context 'These chemotactic attracted CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd34]
<Options>: A: cd344 (homo sapiens) (aka frizzled class receptor 4)
B: cd34 (gallus gallus) (aka cd34 molecule)
C: cd34 (sus scrofa) (aka cd34 molecule)
D: cd34 molecule (homo sapiens) (aka cd34 molecule)
E: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
F: None of the above. | [D] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
... | [N; H; L; B] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
B: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
C: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
D: cd34 molecule (homo sapiens) (aka cd34 molecu... | [R; K; S; D] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
B: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
C: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
D: fat4 (ho... | [T; K; C; I] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: ip-10 (mus musculus) (aka c-x-c motif chemokine ligand 10)
B: fat4 (homo sapiens) (aka fat atypical cadherin 4)
C: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
D: cd114 (homo sapiens) (aka colony stimulating factor 3 recept... | [H; J; G; T] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [gamma ip-10; mig; gm-csf; cd34]
<Options>: A: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
B: cd344 (homo sapiens) (aka frizzled class receptor 4)
C: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: cd34 (gallus gallus) (aka cd34 molecule)
E: nectin-4 (homo sapiens) (aka nectin... | [C; N; I; M] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: gip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: cxcr3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
C: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
D: c-x-c motif chemokine receptor 3 (xenopus tropicali... | [B; A; E] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: c-x-c motif chemokine receptor 3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
B: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
C: cc-ckr-9 (homo sapiens) (aka c-c motif chemokine receptor 9)
D: mig (homo sapiens) (aka c-x-c motif chemokine lig... | [A; L; D] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [cxcr3; gammaip-10; mig]
<Options>: A: cd2f-10 (homo sapiens) (aka slam family member 9)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: mig9 (homo sapiens) (aka s100 calcium binding protein p)
D: pla2g10ip (homo sapiens) (aka phospholipase a2 group xi, pseudogene)
E... | [K; O; N] |
<Instruct>: Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', select the... | <Mentions>: [chemokine stromal cell-derived factor 1 alpha]
<Options>: A: sdf2l1 (homo sapiens) (aka stromal cell derived factor 2 like 1)
B: sdf1 (homo sapiens) (aka c-x-c motif chemokine ligand 12)
C: mip-1-alpha (homo sapiens) (aka c-c motif chemokine ligand 3)
D: sdf-5 (homo sapiens) (aka secreted frizzled related ... | [B] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: glycoprotein ix platelet (homo sapiens) (aka glycoprotein ix platelet)
B: itga9 (homo sapiens) (aka integrin subunit alpha 9)
C: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
D: il-10a (homo sapiens) (aka interleukin 10)
E: cd41b (homo sapiens)... | [H; S; Q; O] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: ip-10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
B: cd49d (homo sapiens) (aka integrin subunit alpha 4)
C: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
D: mig11 (homo sapiens) (aka molybdenum cofactor synthesis 1)... | [A; M; H; I] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: glycoprotein ix platelet (homo sapiens) (aka glycoprotein ix platelet)
B: ifi10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
C: cd49d (homo sapiens) (aka integrin subunit alpha 4)
D: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
E: ip-10 ... | [B; M; R; H] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: mig1 (homo sapiens) (aka vacuolar protein sorting 4 homolog b)
B: cd49b (homo sapiens) (aka integrin subunit alpha 2)
C: mig-14 (homo sapiens) (aka wnt ligand secretion mediator)
D: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member ... | [I; R; L; B] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gamma ip-10; mig; cd49a; cd49b]
<Options>: A: il-10c (homo sapiens) (aka interleukin 19)
B: cd49a (homo sapiens) (aka integrin subunit alpha 1)
C: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
D: glycoprotein ib platelet subunit beta (homo sapiens) (aka glycoprotein ib platelet subunit beta)... | [Q; O; B; H] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gm-csf; cd34]
<Options>: A: cd344 (homo sapiens) (aka frizzled class receptor 4)
B: cd34 (sus scrofa) (aka cd34 molecule)
C: cd34 (homo sapiens) (cd34 molecule (homo sapiens)) (aka cd34 molecule)
D: multi-csf (homo sapiens) (aka interleukin 3)
E: gm-csf (mus musculus) (aka colony stimulating factor 2 (gran... | [J; C] |
<Instruct>: Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [gm-csf; cd34]
<Options>: A: cd344 (homo sapiens) (aka frizzled class receptor 4)
B: nectin-4 (homo sapiens) (aka nectin cell adhesion molecule 4)
C: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
D: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
E: csf-1 (homo sa... | [J; F] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: c-c chemokine receptor type 3 (xenopus tropicalis) (aka c-c chemokine receptor type 3)
B: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
C: c-x-c motif chemokine ligand 10 (homo sapiens) (aka c-x-c motif chemokine ligand 10)
D: gmcsf (homo sapien... | [C; T; N; D] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: interferon alpha 10 (homo sapiens) (aka interferon alpha 10)
B: rxfpr3 (homo sapiens) (aka relaxin family peptide receptor 3)
C: cxcr3 (homo sapiens) (aka c-x-c motif chemokine receptor 3)
D: csf-1 (homo sapiens) (aka colony stimulating factor 1)
E: cc-ckr-9 (... | [T; Q; C; H] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: csf1 (homo sapiens) (aka colony stimulating factor 1)
B: interleukin 10 (homo sapiens) (aka interleukin 10)
C: multi-csf (homo sapiens) (aka interleukin 3)
D: mig-6 (homo sapiens) (aka erbb receptor feedback inhibitor 1)
E: cc-ckr-3 (homo sapiens) (aka c-c mot... | [L; G; K; N] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: c-x-c motif chemokine receptor 3 (xenopus tropicalis) (aka c-x-c motif chemokine receptor 3)
D: ... | [G; P; K; T] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [gamma ip-10; mig; cxcr3; gm-csf]
<Options>: A: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
B: interleukin 1 family member 10 (homo sapiens) (aka interleukin 1 family member 10)
C: gmcsf (homo sapiens) (aka colony stimulating factor 2)
D: mig1 (homo sapiens) (aka vacuolar pr... | [S; G; I; C] |
<Instruct>: Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [cd34]
<Options>: A: cd34 molecule (homo sapiens) (aka cd34 molecule)
B: cd340 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: fat4 (homo sapiens) (aka fat atypical cadherin 4)
D: cd34 (sus scrofa) (aka cd34 molecule)
E: cd344 (homo sapiens) (aka frizzled class receptor 4)
F: None of the above. | [A] |
<Instruct>: Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progen... | <Mentions>: [cxcr3; gamma ip-10; mig]
<Options>: A: mig (homo sapiens) (aka c-x-c motif chemokine ligand 9)
B: il-10c (homo sapiens) (aka interleukin 19)
C: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
D: mig15 (homo sapiens) (aka delta 4-desaturase, sphingolipid 1)
E: rxfpr3... | [F; I; A] |
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