instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca5; mitochondrial carbonic anhydrase v; carbonic anhydrase v; ca v]
<Options>: A: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
B: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
C: carbonic anhydrase 4 (homo sapiens) (aka carbonic anhydrase 4)
D: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
E: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
F: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
G: ca-xiv (mus musculus) (aka carbonic anhydrase 14)
H: carbonic anhydrase 7 (homo sapiens) (aka carbonic anhydrase 7)
I: carbonic anhydrase 5a, mitochondrial-like (homo sapiens) (aka carbonic anhydrase 5a, mitochondrial-like)
J: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
K: None of the above. | [A; A; A; A] |
<Instruct>: Given the context 'It is of interest for its putative roles in providing bicarbonate to carbamoyl phosphate synthetase for ureagenesis and to pyruvate carboxylase for gluconeogenesis and its possible importance in explaining certain inherited metabolic disorders with hyperammonemia and hypoglycemia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [pyruvate carboxylase]
<Options>: A: pc (homo sapiens) (pyruvate carboxylase (homo sapiens)) (aka pyruvate carboxylase)
B: pyruvate carboxylase (oryctolagus cuniculus) (aka pyruvate carboxylase)
C: pepckc (homo sapiens) (aka phosphoenolpyruvate carboxykinase 1)
D: pyruvate carboxylase (xenopus tropicalis) (aka pyruvate carboxylase)
E: pyruvate carboxylase (sus scrofa) (aka pyruvate carboxylase)
F: None of the above. | [A] |
<Instruct>: Given the context 'Following the recent characterization of the cDNA for human CA V, we report the isolation of the human gene from two lambda genomic libraries and its characterization.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca v]
<Options>: A: coagulation factor v (homo sapiens) (aka coagulation factor v)
B: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
C: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
D: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
E: cav (homo sapiens) (carbonic anhydrase 5a (homo sapiens)) (aka carbonic anhydrase 5a)
F: None of the above. | [E] |
<Instruct>: Given the context 'The CA V gene (CA5) is approximately 50 kb long and contains 7 exons and 6 introns.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca v; ca5]
<Options>: A: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
B: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
C: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
D: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
E: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
F: cav (homo sapiens) (carbonic anhydrase 5a (homo sapiens)) (aka carbonic anhydrase 5a)
G: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
H: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
I: None of the above. | [F; F] |
<Instruct>: Given the context 'The CA V gene (CA5) is approximately 50 kb long and contains 7 exons and 6 introns.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca v; ca5]
<Options>: A: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
B: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
C: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
D: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
E: coagulation factor v (homo sapiens) (aka coagulation factor v)
F: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
G: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
H: None of the above. | [F; F] |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca ii; ca iii; ca vii]
<Options>: A: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
B: ca-ii (homo sapiens) (aka carbonic anhydrase 2)
C: ca7 (xenopus tropicalis) (aka carbonic anhydrase vii)
D: caiii (homo sapiens) (aka carbonic anhydrase 3)
E: carbonic anhydrase i (xenopus tropicalis) (aka carbonic anhydrase i)
F: ca-i (homo sapiens) (aka carbonic anhydrase 1)
G: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
H: cn-iii (homo sapiens) (aka 5'-nucleotidase, cytosolic iiia)
I: ac-iii (homo sapiens) (aka adenylate cyclase 3)
J: ca-2 (xenopus laevis) (carbonic anhydrase 2 s homeolog (xenopus laevis)) (aka carbonic anhydrase 2 s homeolog)
K: ca-rp ii (homo sapiens) (aka carbonic anhydrase 11)
L: ca-vii (homo sapiens) (aka carbonic anhydrase 7)
M: carbonic anhydrase 3 (homo sapiens) (aka carbonic anhydrase 3)
N: ca7.s (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
O: None of the above. | [B; M; L] |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca ii; ca iii; ca vii]
<Options>: A: ca7 (gallus gallus) (aka carbonic anhydrase 7)
B: ca-ii (homo sapiens) (aka carbonic anhydrase 2)
C: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
D: cai2 (homo sapiens) (aka cyclin dependent kinase inhibitor 2a)
E: carbonic anhydrase iii (xenopus tropicalis) (aka carbonic anhydrase iii)
F: carbonic anhydrase vii s homeolog (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
G: ca-rp ii (homo sapiens) (aka carbonic anhydrase 11)
H: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
I: ca7 (xenopus tropicalis) (aka carbonic anhydrase vii)
J: ca-ii (xenopus tropicalis) (aka carbonic anhydrase 2)
K: caiii (homo sapiens) (aka carbonic anhydrase 3)
L: ca7 (homo sapiens) (aka carbonic anhydrase 7)
M: carbonic anhydrase 3 (bos taurus) (aka carbonic anhydrase 3)
N: ca(v)3.3 (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 i)
O: carbonic anhydrase 3 (homo sapiens) (aka carbonic anhydrase 3)
P: None of the above. | [B; O; L] |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca ii; ca iii; ca vii]
<Options>: A: ca-rp ii (homo sapiens) (aka carbonic anhydrase 11)
B: ca7.s (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
C: carbonic anhydrase 3 (homo sapiens) (aka carbonic anhydrase 3)
D: carbonic anhydrase vii (xenopus tropicalis) (aka carbonic anhydrase vii)
E: carbonic anhydrase 3a (gallus gallus) (aka carbonic anhydrase 3a)
F: ca-vii (homo sapiens) (aka carbonic anhydrase 7)
G: caiii (homo sapiens) (aka carbonic anhydrase 3)
H: ca ii (xenopus tropicalis) (aka carbonic anhydrase 2)
I: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
J: cai2 (homo sapiens) (aka cyclin dependent kinase inhibitor 2a)
K: carbonic anhydrase 3 (bos taurus) (aka carbonic anhydrase 3)
L: ca-ii (homo sapiens) (aka carbonic anhydrase 2)
M: carbonic anhydrase i (xenopus tropicalis) (aka carbonic anhydrase i)
N: car3 (xenopus tropicalis) (carbonic anhydrase iii (xenopus tropicalis)) (aka carbonic anhydrase iii)
O: ca7 (gallus gallus) (aka carbonic anhydrase 7)
P: None of the above. | [L; C; F] |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca vii; ca5]
<Options>: A: ca7.s (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
B: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
C: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
D: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
E: carbonic anhydrase vii (xenopus tropicalis) (aka carbonic anhydrase vii)
F: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
G: ca7 (homo sapiens) (aka carbonic anhydrase 7)
H: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
I: ca7 (gallus gallus) (aka carbonic anhydrase 7)
J: ca7.5 (mus musculus) (aka dna segment, ca7.5)
K: None of the above. | [G; H] |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca vii; ca5]
<Options>: A: ca7.s (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
B: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
C: carbonic anhydrase vii (xenopus tropicalis) (aka carbonic anhydrase vii)
D: ca7 (gallus gallus) (aka carbonic anhydrase 7)
E: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
F: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
G: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
H: ca7.5 (mus musculus) (aka dna segment, ca7.5)
I: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
J: None of the above. | [J; I] |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca vii; ca5]
<Options>: A: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
B: ca7 (gallus gallus) (aka carbonic anhydrase 7)
C: ca7 (xenopus tropicalis) (aka carbonic anhydrase vii)
D: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
E: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
F: carbonic anhydrase 7 (homo sapiens) (aka carbonic anhydrase 7)
G: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
H: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
I: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
J: ca7.5 (mus musculus) (aka dna segment, ca7.5)
K: None of the above. | [F; A] |
<Instruct>: Given the context 'CA5 also contains a 12-bp GT-rich segment beginning 13 bp downstream of the polyadenylation signal in the 3' untranslated region of exon 7.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca5]
<Options>: A: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
B: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
C: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
D: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
E: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
F: None of the above. | [D] |
<Instruct>: Given the context 'FISH analysis allowed CA5 to be assigned to chromosome 16q24.3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ca5]
<Options>: A: ca5d (homo sapiens) (aka carbonic anhydrase 5a)
B: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
C: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
D: ca7.5 (mus musculus) (aka dna segment, ca7.5)
E: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
F: None of the above. | [A] |
<Instruct>: Given the context 'Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [brca1]
<Options>: A: brca1p1 (homo sapiens) (aka brca1 pseudogene 1)
B: brca1 dna repair associated (homo sapiens) (aka brca1 dna repair associated)
C: breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans) (aka breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1)
D: brca1 associated protein (homo sapiens) (aka brca1 associated protein)
E: brisc and brca1 a complex member 1 (homo sapiens) (aka brisc and brca1 a complex member 1)
F: None of the above. | [B] |
<Instruct>: Given the context 'Fragments corresponding to the broadly expressed gamma-tubulin and Ki antigen genes were identified.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ki antigen]
<Options>: A: marker of proliferation ki-67 (gallus gallus) (aka marker of proliferation ki-67)
B: antigen identified by monoclonal antibody ki 67 (mus musculus) (aka antigen identified by monoclonal antibody ki 67)
C: kia (homo sapiens) (aka marker of proliferation ki-67)
D: ki (homo sapiens) (aka proteasome activator subunit 3)
E: marker of proliferation ki-67 (bos taurus) (aka marker of proliferation ki-67)
F: None of the above. | [D] |
<Instruct>: Given the context 'A full-length cDNA clone encoding a 117-amino-acid protein homologous to the rat ribosomal protein L34 was isolated.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ribosomal protein l34]
<Options>: A: ribosomal protein l34 (homo sapiens) (aka ribosomal protein l34)
B: l34 (drosophila melanogaster) (ribosomal protein l34a (drosophila melanogaster)) (aka ribosomal protein l34a)
C: l34 (xenopus laevis) (ribosomal protein l34 l homeolog (xenopus laevis)) (aka ribosomal protein l34 l homeolog)
D: ribosomal protein l34 (xenopus tropicalis) (aka ribosomal protein l34)
E: mitochondrial ribosomal protein l34 (homo sapiens) (aka mitochondrial ribosomal protein l34)
F: None of the above. | [F] |
<Instruct>: Given the context 'Portions of genes with restricted patterns of expression were also obtained, including the previously characterized HSD17B1.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hsd17b1]
<Options>: A: hsd17b1 promoter (homo sapiens) (aka hsd17b1 promoter)
B: hsd17b11 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 11)
C: hsd11b1 (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
D: hsd17b1 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 1)
E: hsd17b2 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 2)
F: None of the above. | [D] |
<Instruct>: Given the context 'A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3]
<Options>: A: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: hkvbeta2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
C: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
D: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
E: None of the above. | [A] |
<Instruct>: Given the context 'We report here a novel K+ channel beta-subunit cloned from human heart, hKv beta 1.3, that has 74-83% overall identity with previously cloned beta-subunits.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3]
<Options>: A: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
B: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
C: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
D: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
E: None of the above. | [C] |
<Instruct>: Given the context 'We report here a novel K+ channel beta-subunit cloned from human heart, hKv beta 1.3, that has 74-83% overall identity with previously cloned beta-subunits.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3]
<Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
D: None of the above. | [D] |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3; hkv beta 3; rkv beta 1]
<Options>: A: kv-beta-1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: rvb1 (homo sapiens) (aka ruvb like aaa atpase 1)
C: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
D: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: k(vca)beta-1 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 1)
F: k(vca)beta-3 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 3)
G: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
H: k(vca)beta-1 (rattus norvegicus) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 1)
I: kv-beta-3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 3)
J: potassium channel, voltage gated subfamily a regulatory beta subunit 1 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
K: potassium voltage-gated channel subfamily a regulatory beta subunit 1 (rattus norvegicus) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
L: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
M: hkvbeta2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
N: None of the above. | [A; L; K] |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3; hkv beta 3; rkv beta 1]
<Options>: A: potassium voltage-gated channel subfamily a regulatory beta subunit 1 (rattus norvegicus) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: hkvbeta3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
C: similar to rt1 class ii histocompatibility antigen, b-1 beta chain precursor (rt1.b-beta(1)) (rattus norvegicus) (aka similar to rt1 class ii histocompatibility antigen, b-1 beta chain precursor (rt1.b-beta(1)))
D: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
E: kv-beta-3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 3)
F: bkbeta1 (rattus norvegicus) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 1)
G: k(vca)beta-1 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 1)
H: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
I: rvb1 (homo sapiens) (aka ruvb like aaa atpase 1)
J: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
K: slo-beta-3 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 3)
L: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
M: None of the above. | [B; H; A] |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3; hkv beta 3; rkv beta 1]
<Options>: A: k(vca)beta-1 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 1)
B: bkbeta1 (rattus norvegicus) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 1)
C: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
D: kv-beta-1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: kv-beta-2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
F: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
G: k(vca)beta-3 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 3)
H: kv-beta-3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 3)
I: rvb1 (homo sapiens) (aka ruvb like aaa atpase 1)
J: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
K: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
L: potassium voltage-gated channel subfamily a regulatory beta subunit 1 (rattus norvegicus) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
M: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
N: None of the above. | [F; J; L] |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3; hkv1.5]
<Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: kv-beta-1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
D: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
E: kv7.5 (homo sapiens) (aka potassium voltage-gated channel subfamily q member 5)
F: kv1.5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
G: task-5 (homo sapiens) (aka potassium two pore domain channel subfamily k member 15)
H: potassium channel, subfamily v, member 1 (mus musculus) (aka potassium channel, subfamily v, member 1)
I: kv5.1 (homo sapiens) (aka potassium voltage-gated channel modifier subfamily f member 1)
J: None of the above. | [C; F] |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3; hkv1.5]
<Options>: A: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: potassium channel, subfamily v, member 1 (mus musculus) (aka potassium channel, subfamily v, member 1)
C: kv5.1 (homo sapiens) (aka potassium voltage-gated channel modifier subfamily f member 1)
D: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
E: kv1.5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
F: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
G: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
H: hkv9.1 (homo sapiens) (aka potassium voltage-gated channel modifier subfamily s member 1)
I: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog)
J: None of the above. | [A; E] |
<Instruct>: Given the context 'Most notably, hKv beta 1.3 converted the Kv1.5 outwardly rectifying current voltage relationship to one showing strong inward rectification.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3; kv1.5]
<Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv7.5 (homo sapiens) (aka potassium voltage-gated channel subfamily q member 5)
C: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
D: potassium channel, subfamily k, member 5 (mus musculus) (aka potassium channel, subfamily k, member 5)
E: task5 (homo sapiens) (aka potassium two pore domain channel subfamily k member 15)
F: kv1.5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
G: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog)
H: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
I: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
J: None of the above. | [I; F] |
<Instruct>: Given the context 'Most notably, hKv beta 1.3 converted the Kv1.5 outwardly rectifying current voltage relationship to one showing strong inward rectification.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hkv beta 1.3; kv1.5]
<Options>: A: kv7.5 (homo sapiens) (aka potassium voltage-gated channel subfamily q member 5)
B: kv5.1 (homo sapiens) (aka potassium voltage-gated channel modifier subfamily f member 1)
C: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
D: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
E: potassium voltage-gated channel subfamily a member 5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
F: kcnh5 (homo sapiens) (aka potassium voltage-gated channel subfamily h member 5)
G: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
H: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog)
I: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
J: None of the above. | [I; E] |
<Instruct>: Given the context 'De novo mutation of the myelin P0 gene in Dejerine-Sottas disease (hereditary motor and sensory neuropathy type III).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [myelin p0]
<Options>: A: myelin protein zero-like 1 (rattus norvegicus) (aka myelin protein zero-like 1)
B: myelin protein zero (rattus norvegicus) (aka myelin protein zero)
C: p0 (mus musculus) (aka myelin protein zero)
D: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
E: myelin protein zero (homo sapiens) (aka myelin protein zero)
F: None of the above. | [E] |
<Instruct>: Given the context 'We have investigated the myelin P0 gene on chromosome 1 as a candidate gene in two sporadic cases with Dejerine-Sottas disease or hereditary motor and sensory neuropathy (HMSN) type III.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [myelin p0]
<Options>: A: myelin protein zero (rattus norvegicus) (aka myelin protein zero)
B: myelin protein zero (homo sapiens) (aka myelin protein zero)
C: myelin protein zero-like 1 (rattus norvegicus) (aka myelin protein zero-like 1)
D: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
E: ribosomal protein lateral stalk subunit p0 (rattus norvegicus) (aka ribosomal protein lateral stalk subunit p0)
F: None of the above. | [B] |
<Instruct>: Given the context 'The results strongly suggest that a de novo dominant mutation of the P0 gene is responsible for at least some sporadic cases of Dejerine-Sottas disease.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p0]
<Options>: A: ribosomal protein, large, p0 (xenopus tropicalis) (aka ribosomal protein, large, p0)
B: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
C: p0 (homo sapiens) (myelin protein zero (homo sapiens)) (aka myelin protein zero)
D: prlp0 (xenopus laevis) (ribosomal protein, large, p0 s homeolog (xenopus laevis)) (aka ribosomal protein, large, p0 s homeolog)
E: ribosomal protein lateral stalk subunit p0 (homo sapiens) (aka ribosomal protein lateral stalk subunit p0)
F: None of the above. | [C] |
<Instruct>: Given the context 'The results strongly suggest that a de novo dominant mutation of the P0 gene is responsible for at least some sporadic cases of Dejerine-Sottas disease.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p0]
<Options>: A: prlp0 (xenopus laevis) (ribosomal protein, large, p0 s homeolog (xenopus laevis)) (aka ribosomal protein, large, p0 s homeolog)
B: ribosomal protein lateral stalk subunit p0 (homo sapiens) (aka ribosomal protein lateral stalk subunit p0)
C: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
D: ribosomal protein, large, p0 (xenopus tropicalis) (aka ribosomal protein, large, p0)
E: None of the above. | [E] |
<Instruct>: Given the context 'Human serum biotinidase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [biotinidase]
<Options>: A: biotinidase (oryctolagus cuniculus) (aka biotinidase)
B: biotinidase (rattus norvegicus) (aka biotinidase)
C: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
D: biotinidase (homo sapiens) (aka biotinidase)
E: biotinidase (mus musculus) (aka biotinidase)
F: None of the above. | [D] |
<Instruct>: Given the context 'cDNA cloning, sequence, and characterization.
Biotinidase (EC 3.5.1.12) catalyzes the hydrolysis of biocytin, the product of biotin-dependent carboxylase degradation, to biotin and lysine.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [biotinidase]
<Options>: A: biotinidase (homo sapiens) (aka biotinidase)
B: biotinidase (rattus norvegicus) (aka biotinidase)
C: biotinidase (gallus gallus) (aka biotinidase)
D: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
E: biotinidase (sus scrofa) (aka biotinidase)
F: None of the above. | [A] |
<Instruct>: Given the context 'Biotinidase deficiency is an inherited metabolic disorder of biotin recycling that is characterized by neurological and cutaneous abnormalities, and can be successfully treated with biotin supplementation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [biotinidase]
<Options>: A: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
B: biotinidase (rattus norvegicus) (aka biotinidase)
C: biotinidase (sus scrofa) (aka biotinidase)
D: biotinidase (mus musculus) (aka biotinidase)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | [E] |
<Instruct>: Given the context 'Sequences of tryptic peptides of the purified human serum enzyme were used to design oligonucleotide primers for polymerase chain reaction amplification from human hepatic total RNA to generate putative biotinidase cDNA fragments.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [biotinidase]
<Options>: A: biotinidase (homo sapiens) (aka biotinidase)
B: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
C: biotinidase (oryctolagus cuniculus) (aka biotinidase)
D: biotinidase (gallus gallus) (aka biotinidase)
E: biotinase (bos taurus) (aka biotinidase)
F: None of the above. | [A] |
<Instruct>: Given the context 'Comparison of the open reading frame with the known biotinidase tryptic peptides and recognition of the expressed protein encoded by this cDNA by monoclonal antibodies prepared against purified biotinidase demonstrated the identity of this cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [biotinidase]
<Options>: A: biotinidase (sus scrofa) (aka biotinidase)
B: biotinidase (gallus gallus) (aka biotinidase)
C: biotinidase (rattus norvegicus) (aka biotinidase)
D: biotinidase (xenopus tropicalis) (aka biotinidase)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | [E] |
<Instruct>: Given the context 'Southern analyses suggested that biotinidase is a single copy gene and revealed that human cDNA probes hybridized to genomic DNA from mammals, but not from chicken or yeast.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [biotinidase]
<Options>: A: biotinidase (xenopus tropicalis) (aka biotinidase)
B: biotinidase (bos taurus) (aka biotinidase)
C: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
D: biotinidase (mus musculus) (aka biotinidase)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | [E] |
<Instruct>: Given the context 'Northern analysis indicated the presence of biotinidase mRNA in human heart, brain, placenta, liver, lung, skeletal muscle, kidney, and pancreas.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [biotinidase]
<Options>: A: biotinidase (sus scrofa) (aka biotinidase)
B: biotinidase (gallus gallus) (aka biotinidase)
C: biotinidase (rattus norvegicus) (aka biotinidase)
D: biotinidase (homo sapiens) (aka biotinidase)
E: biotinidase (bos taurus) (aka biotinidase)
F: None of the above. | [D] |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: crk proto-oncogene, adaptor protein (homo sapiens) (aka crk proto-oncogene, adaptor protein)
B: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
C: ash 1 (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
D: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
E: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
F: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
G: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
H: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
I: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
J: c1qg (homo sapiens) (aka complement c1q c chain)
K: grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
L: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
M: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
N: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
O: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
P: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
Q: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
R: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
S: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
T: None of the above. | [B; A; K; K] |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
B: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
C: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
D: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
E: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
F: crk proto-oncogene, adaptor protein (homo sapiens) (aka crk proto-oncogene, adaptor protein)
G: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
H: complement c3 (homo sapiens) (aka complement c3)
I: grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
J: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
K: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
L: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
M: ash1-related protein 1 (arabidopsis thaliana) (aka set domain group 26)
N: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
O: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
P: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
Q: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
R: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
S: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
T: None of the above. | [N; F; I; I] |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: c3b (homo sapiens) (aka complement c3)
B: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
C: ash 1 (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
D: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
E: ashr1 (arabidopsis thaliana) (aka set domain group 37)
F: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
G: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
H: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
I: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
J: ash1-related protein 1 (arabidopsis thaliana) (aka set domain group 26)
K: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
L: growth factor receptor bound protein 2 (homo sapiens) (aka growth factor receptor bound protein 2)
M: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
N: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
O: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
P: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
Q: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
R: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
S: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
T: None of the above. | [O; R; L; L] |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
B: ash1-related protein 1 (arabidopsis thaliana) (aka set domain group 26)
C: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
D: ash 1 (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
E: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
F: c1qg (homo sapiens) (aka complement c1q c chain)
G: crk oncogene (drosophila melanogaster) (aka crk oncogene)
H: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
I: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
J: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
K: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
L: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
M: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
N: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
O: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
P: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
Q: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
R: ashr1 (arabidopsis thaliana) (aka set domain group 37)
S: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
T: None of the above. | [N; P; A; A] |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; grb2; ash]
<Options>: A: growth factor receptor bound protein 2 (homo sapiens) (aka growth factor receptor bound protein 2)
B: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
C: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
D: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
E: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
F: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
G: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
H: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
I: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
J: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
K: ash1-related protein 1 (arabidopsis thaliana) (aka set domain group 26)
L: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
M: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
N: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
O: None of the above. | [D; A; A] |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; grb2; ash]
<Options>: A: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
B: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
C: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
D: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
E: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
F: grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
G: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
H: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
I: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
J: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
K: crk proto-oncogene, adaptor protein (homo sapiens) (aka crk proto-oncogene, adaptor protein)
L: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
M: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
N: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
O: None of the above. | [K; F; F] |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; grb2; ash]
<Options>: A: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
B: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
C: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
D: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
E: grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
F: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
G: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
H: crk proto-oncogene, adaptor protein (homo sapiens) (aka crk proto-oncogene, adaptor protein)
I: ash1 related protein 1 (arabidopsis thaliana) (aka set domain group 26)
J: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
K: ashr1 (arabidopsis thaliana) (aka set domain group 37)
L: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
M: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
N: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
O: None of the above. | [H; E; E] |
<Instruct>: Given the context 'Here another guanine nucleotide-releasing protein (GNRP), C3G, has been identified as a CRK SH3-binding protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk sh3-binding protein]
<Options>: A: crk like proto-oncogene, adaptor protein (homo sapiens) (aka crk like proto-oncogene, adaptor protein)
B: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
C: v-crk avian sarcoma virus ct10 oncogene homolog-like (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog-like)
D: crk (homo sapiens) (aka crk proto-oncogene, adaptor protein)
E: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
F: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
G: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
H: c3b (homo sapiens) (aka complement c3)
I: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
J: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
K: None of the above. | [I; I] |
<Instruct>: Given the context 'Here another guanine nucleotide-releasing protein (GNRP), C3G, has been identified as a CRK SH3-binding protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk sh3-binding protein]
<Options>: A: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
B: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
C: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
D: crk like proto-oncogene, adaptor protein (homo sapiens) (aka crk like proto-oncogene, adaptor protein)
E: c3b (homo sapiens) (aka complement c3)
F: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
G: v-crk avian sarcoma virus ct10 oncogene homolog-like (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog-like)
H: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
I: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
J: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
K: None of the above. | [C; C] |
<Instruct>: Given the context 'The nucleotide sequence of a 4.1-kb C3G cDNA contains a 3.2-kb open reading frame encoding a 121-kDa protein, and antibodies against C3G have been shown to detect a protein of 130-140 kDa.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g]
<Options>: A: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
B: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
C: c3b (homo sapiens) (aka complement c3)
D: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
E: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
F: None of the above. | [B] |
<Instruct>: Given the context 'The carboxyl terminus of C3G has a peptide sequence homologous to GNRPs for Ras, and the expression of this carboxyl terminus region suppresses the loss of CDC25 function in the yeast Saccharomyces cerevisiae.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; cdc25]
<Options>: A: cdc25a (xenopus laevis) (cell division cycle 25c s homeolog (xenopus laevis)) (aka cell division cycle 25c s homeolog)
B: cdc25d (xenopus laevis) (provisional ortholog of cell division cycle 25c s homeolog (xenopus laevis)) (aka provisional ortholog of cell division cycle 25c s homeolog)
C: cdc25b (homo sapiens) (aka cell division cycle 25b)
D: cdc25 (saccharomyces cerevisiae s288c) (aka ras family guanine nucleotide exchange factor cdc25)
E: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
F: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
G: cdc25 (homo sapiens) (cell division cycle 25c (homo sapiens)) (aka cell division cycle 25c)
H: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
I: c3b (homo sapiens) (aka complement c3)
J: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
K: None of the above. | [J; D] |
<Instruct>: Given the context 'The carboxyl terminus of C3G has a peptide sequence homologous to GNRPs for Ras, and the expression of this carboxyl terminus region suppresses the loss of CDC25 function in the yeast Saccharomyces cerevisiae.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; cdc25]
<Options>: A: cdc25d (xenopus laevis) (provisional ortholog of cell division cycle 25c l homeolog (xenopus laevis)) (aka provisional ortholog of cell division cycle 25c l homeolog)
B: cdc25a (homo sapiens) (aka cell division cycle 25a)
C: cdc25 (saccharomyces cerevisiae s288c) (aka ras family guanine nucleotide exchange factor cdc25)
D: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
E: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
F: cdc25 (xenopus laevis) (cell division cycle 25c l homeolog (xenopus laevis)) (aka cell division cycle 25c l homeolog)
G: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
H: c3b (homo sapiens) (aka complement c3)
I: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
J: cdc25d (xenopus laevis) (provisional ortholog of cell division cycle 25c s homeolog (xenopus laevis)) (aka provisional ortholog of cell division cycle 25c s homeolog)
K: None of the above. | [I; C] |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: c1qg (homo sapiens) (aka complement c1q c chain)
B: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
C: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
D: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
E: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
F: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
G: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
H: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
I: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
J: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
K: ash1-related protein 1 (arabidopsis thaliana) (aka set domain group 26)
L: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
M: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
N: complement c3 (homo sapiens) (aka complement c3)
O: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
P: egfrbp-grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
Q: ash 1 (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
R: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
S: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
T: None of the above. | [F; O; P; P] |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: complement c3 (homo sapiens) (aka complement c3)
B: crk proto-oncogene, adaptor protein (homo sapiens) (aka crk proto-oncogene, adaptor protein)
C: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
D: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
E: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
F: ash1 related protein 1 (arabidopsis thaliana) (aka set domain group 26)
G: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
H: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
I: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
J: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
K: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
L: ashr1 (arabidopsis thaliana) (aka set domain group 37)
M: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
N: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
O: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
P: egfrbp-grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
Q: c1qg (homo sapiens) (aka complement c1q c chain)
R: gab2 (homo sapiens) (aka grb2 associated binding protein 2)
S: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
T: None of the above. | [E; B; P; P] |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: c3b (homo sapiens) (aka complement c3)
B: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
C: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
D: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
E: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
F: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
G: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
H: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
I: ash 1 (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
J: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
K: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
L: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
M: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
N: gab2 (homo sapiens) (aka grb2 associated binding protein 2)
O: ash1-related protein 1 (arabidopsis thaliana) (aka set domain group 26)
P: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
Q: growth factor receptor bound protein 2 (homo sapiens) (aka growth factor receptor bound protein 2)
R: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
S: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
T: None of the above. | [M; B; Q; Q] |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk; grb2; ash]
<Options>: A: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
B: c1qg (homo sapiens) (aka complement c1q c chain)
C: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
D: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
E: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
F: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
G: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
H: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
I: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
J: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
K: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
L: ash1-related protein 1 (arabidopsis thaliana) (aka set domain group 26)
M: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
N: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
O: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
P: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
Q: ashr1 (arabidopsis thaliana) (aka set domain group 37)
R: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
S: egfrbp-grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
T: None of the above. | [R; J; S; S] |
<Instruct>: Given the context 'Mutational analysis of C3G assigns the SH3 binding region to a 50-amino acid region containing a proline-rich sequence.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g]
<Options>: A: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
B: c3b (homo sapiens) (aka complement c3)
C: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
D: c1qg (homo sapiens) (aka complement c1q c chain)
E: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
F: None of the above. | [E] |
<Instruct>: Given the context 'The mRNAs of both the C3G and CRK proteins are expressed ubiquitously in human adult and fetal tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk]
<Options>: A: c1qg (homo sapiens) (aka complement c1q c chain)
B: crk (homo sapiens) (aka crk proto-oncogene, adaptor protein)
C: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
D: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
E: c3b (homo sapiens) (aka complement c3)
F: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
G: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
H: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
I: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
J: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
K: None of the above. | [J; B] |
<Instruct>: Given the context 'The mRNAs of both the C3G and CRK proteins are expressed ubiquitously in human adult and fetal tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk]
<Options>: A: crk (homo sapiens) (aka crk proto-oncogene, adaptor protein)
B: c3b (homo sapiens) (aka complement c3)
C: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
D: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
E: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
F: c1qg (homo sapiens) (aka complement c1q c chain)
G: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
H: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
I: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
J: None of the above. | [J; A] |
<Instruct>: Given the context 'The mRNAs of both the C3G and CRK proteins are expressed ubiquitously in human adult and fetal tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g; crk]
<Options>: A: crk oncogene (drosophila melanogaster) (aka crk oncogene)
B: c1qg (homo sapiens) (aka complement c1q c chain)
C: crk proto-oncogene, adaptor protein (homo sapiens) (aka crk proto-oncogene, adaptor protein)
D: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
E: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
F: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
G: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
H: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
I: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
J: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
K: None of the above. | [I; C] |
<Instruct>: Given the context 'The results of these studies suggest that the complex of CRK and C3G, or GRB2/ASH and C3G, may transduce the signals from tyrosine kinases to Ras in a number of different tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; c3g; grb2; ash]
<Options>: A: ashr1 (arabidopsis thaliana) (aka set domain group 37)
B: complement c3 (homo sapiens) (aka complement c3)
C: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
D: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
E: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
F: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
G: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
H: c1qg (homo sapiens) (aka complement c1q c chain)
I: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
J: crk oncogene (drosophila melanogaster) (aka crk oncogene)
K: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
L: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
M: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
N: ashh1 (arabidopsis thaliana) (aka set domain group 26)
O: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
P: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
Q: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
R: growth factor receptor bound protein 2 (homo sapiens) (aka growth factor receptor bound protein 2)
S: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
T: None of the above. | [F; Q; R; R] |
<Instruct>: Given the context 'The results of these studies suggest that the complex of CRK and C3G, or GRB2/ASH and C3G, may transduce the signals from tyrosine kinases to Ras in a number of different tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; c3g; grb2; ash]
<Options>: A: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
B: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
C: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
D: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
E: grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
F: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
G: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
H: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
I: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
J: ashr1 (arabidopsis thaliana) (aka set domain group 37)
K: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
L: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
M: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
N: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
O: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
P: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
Q: ash1 related protein 1 (arabidopsis thaliana) (aka set domain group 26)
R: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
S: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
T: None of the above. | [K; A; E; E] |
<Instruct>: Given the context 'The results of these studies suggest that the complex of CRK and C3G, or GRB2/ASH and C3G, may transduce the signals from tyrosine kinases to Ras in a number of different tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; c3g; grb2; ash]
<Options>: A: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
B: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
C: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
D: grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
E: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
F: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
G: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
H: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
I: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
J: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
K: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
L: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
M: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
N: ash1 related protein 1 (arabidopsis thaliana) (aka set domain group 26)
O: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
P: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
Q: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
R: ashr1 (arabidopsis thaliana) (aka set domain group 37)
S: None of the above. | [S; E; D; D] |
<Instruct>: Given the context 'The results of these studies suggest that the complex of CRK and C3G, or GRB2/ASH and C3G, may transduce the signals from tyrosine kinases to Ras in a number of different tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; c3g; grb2; ash]
<Options>: A: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
B: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
C: crk proto-oncogene, adaptor protein (homo sapiens) (aka crk proto-oncogene, adaptor protein)
D: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
E: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
F: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
G: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
H: c1qg (homo sapiens) (aka complement c1q c chain)
I: grb2 related adaptor protein 2 (homo sapiens) (aka grb2 related adaptor protein 2)
J: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
K: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
L: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
M: c3b (homo sapiens) (aka complement c3)
N: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
O: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
P: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
Q: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
R: growth factor receptor bound protein 2 (homo sapiens) (aka growth factor receptor bound protein 2)
S: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
T: None of the above. | [C; K; R; R] |
<Instruct>: Given the context 'The results of these studies suggest that the complex of CRK and C3G, or GRB2/ASH and C3G, may transduce the signals from tyrosine kinases to Ras in a number of different tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crk; c3g; grb2; ash]
<Options>: A: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
B: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
C: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
D: ashh1 (arabidopsis thaliana) (aka set domain group 26)
E: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
F: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
G: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
H: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
I: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
J: c1qg (homo sapiens) (aka complement c1q c chain)
K: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
L: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
M: ashr1 (arabidopsis thaliana) (aka set domain group 37)
N: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
O: egfrbp-grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
P: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
Q: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
R: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
S: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
T: None of the above. | [F; P; O; O] |
<Instruct>: Given the context 'The results of these studies suggest that the complex of CRK and C3G, or GRB2/ASH and C3G, may transduce the signals from tyrosine kinases to Ras in a number of different tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c3g]
<Options>: A: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
B: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
C: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
D: c3 (homo sapiens) (aka complement c3)
E: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
F: None of the above. | [B] |
<Instruct>: Given the context 'A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc; cdc20; cdc4]
<Options>: A: cdc20/fzy (drosophila melanogaster) (aka fizzy)
B: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
C: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
D: cell division cycle 25c (homo sapiens) (aka cell division cycle 25c)
E: p55cdc (homo sapiens) (aka cell division cycle 20)
F: cdc20b (homo sapiens) (aka cell division cycle 20b)
G: cdc4 (candida albicans sc5314) (aka scf ubiquitin ligase complex subunit)
H: cdc4 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit cdc4)
I: cdc24 (saccharomyces cerevisiae s288c) (aka rho family guanine nucleotide exchange factor cdc24)
J: cdc20p (homo sapiens) (aka cell division cycle 20 pseudogene 1)
K: dna replication licensing factor mcm-4 (caenorhabditis elegans) (aka dna replication licensing factor mcm-4)
L: cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
M: cdc20 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein cdc20)
N: cdc20c (homo sapiens) (aka fizzy and cell division cycle 20 related 1)
O: mcm dna helicase complex subunit mcm4 (saccharomyces cerevisiae s288c) (aka mcm dna helicase complex subunit mcm4)
P: None of the above. | [E; M; H] |
<Instruct>: Given the context 'A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc; cdc20; cdc4]
<Options>: A: cdc20[fizzy] (drosophila melanogaster) (aka fizzy)
B: p55cdc (mus musculus) (aka cell division cycle 20)
C: dna replication licensing factor mcm-4 (caenorhabditis elegans) (aka dna replication licensing factor mcm-4)
D: cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
E: mcm dna helicase complex subunit mcm4 (saccharomyces cerevisiae s288c) (aka mcm dna helicase complex subunit mcm4)
F: cdc20c (homo sapiens) (aka fizzy and cell division cycle 20 related 1)
G: cyclin-dependent kinase 4 homolog (caenorhabditis elegans) (aka cyclin-dependent kinase 4 homolog)
H: cdc4 (drosophila melanogaster) (aka archipelago)
I: cdc20 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein cdc20)
J: p55cdc (homo sapiens) (aka cell division cycle 20)
K: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
L: cdc20p (homo sapiens) (aka cell division cycle 20 pseudogene 1)
M: cell division cycle 25c (homo sapiens) (aka cell division cycle 25c)
N: cdc20a (homo sapiens) (aka cell division cycle 20)
O: cdc4 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit cdc4)
P: None of the above. | [J; I; O] |
<Instruct>: Given the context 'A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc; cdc20; cdc4]
<Options>: A: cyclin-dependent kinase 4 homolog (caenorhabditis elegans) (aka cyclin-dependent kinase 4 homolog)
B: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
C: dna replication licensing factor mcm-4 (caenorhabditis elegans) (aka dna replication licensing factor mcm-4)
D: p5cdh (homo sapiens) (aka aldehyde dehydrogenase 4 family member a1)
E: cdc20b (homo sapiens) (aka cell division cycle 20b)
F: protein phosphatase 2a regulatory subunit cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
G: cdc20/fizzy (drosophila melanogaster) (aka fizzy)
H: cdc4 (homo sapiens) (aka f-box and wd repeat domain containing 7)
I: scf ubiquitin ligase complex subunit cdc4 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit cdc4)
J: p55cdc (homo sapiens) (aka cell division cycle 20)
K: cdc20 (homo sapiens) (aka cell division cycle 20)
L: cdc4 (drosophila melanogaster) (aka archipelago)
M: cdc20c (homo sapiens) (aka fizzy and cell division cycle 20 related 1)
N: p55cdc (mus musculus) (aka cell division cycle 20)
O: cdc20 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein cdc20)
P: None of the above. | [J; O; I] |
<Instruct>: Given the context 'A novel protein, p55CDC, has been identified in cycling mammalian cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p55cdc (homo sapiens) (aka cell division cycle 20)
B: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
C: protein phosphatase 2a regulatory subunit cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
D: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
E: cell division cycle 25c (homo sapiens) (aka cell division cycle 25c)
F: None of the above. | [A] |
<Instruct>: Given the context 'The p55CDC protein appears to be essential for cell division, since transfection of antisense p55CDC cDNA into CHO cells resulted in isolation of only those cells which exhibited a compensatory increase in p55CDC transcripts in the sense orientation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p55cdc (homo sapiens) (aka cell division cycle 20)
B: p55cdc (mus musculus) (aka cell division cycle 20)
C: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
D: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
E: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
F: None of the above. | [A] |
<Instruct>: Given the context 'The p55CDC protein appears to be essential for cell division, since transfection of antisense p55CDC cDNA into CHO cells resulted in isolation of only those cells which exhibited a compensatory increase in p55CDC transcripts in the sense orientation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
B: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
C: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
D: p55cdc (mus musculus) (aka cell division cycle 20)
E: None of the above. | [E] |
<Instruct>: Given the context 'Immunoprecipitation of p55CDC yielded protein complexes with kinase activity which fluctuated during the cell cycle.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
B: protein phosphatase 2a regulatory subunit cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
C: p55cdc (mus musculus) (aka cell division cycle 20)
D: p5cdh (homo sapiens) (aka aldehyde dehydrogenase 4 family member a1)
E: p55cdc (homo sapiens) (aka cell division cycle 20)
F: None of the above. | [E] |
<Instruct>: Given the context 'Since p55CDC does not have the conserved protein kinase domains, this activity must be due to one or more of the associated proteins in the immune complex.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p55cdc (mus musculus) (aka cell division cycle 20)
B: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
C: p5cdh (homo sapiens) (aka aldehyde dehydrogenase 4 family member a1)
D: p55cdc (homo sapiens) (aka cell division cycle 20)
E: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
F: None of the above. | [D] |
<Instruct>: Given the context 'The highest levels of protein kinase activity were seen with alpha-casein and myelin basic protein as substrates and demonstrated a pattern of activity distinct from that described for the known cyclin-dependent cell division kinases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [myelin basic protein]
<Options>: A: myelin-associated oligodendrocytic basic protein (mus musculus) (aka myelin-associated oligodendrocytic basic protein)
B: myelin basic protein (homo sapiens) (aka myelin basic protein)
C: myelin basic protein (sus scrofa) (aka myelin basic protein)
D: mbp (mus musculus) (myelin basic protein (mus musculus)) (aka myelin basic protein)
E: myelin basic protein (xenopus tropicalis) (aka myelin basic protein)
F: None of the above. | [B] |
<Instruct>: Given the context 'The p55CDC protein was also phosphorylated in dividing cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p55cdc (mus musculus) (aka cell division cycle 20)
B: cell division cycle 25c (homo sapiens) (aka cell division cycle 25c)
C: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
D: p5cd (homo sapiens) (aka aldehyde dehydrogenase 4 family member a1)
E: p55cdc (homo sapiens) (aka cell division cycle 20)
F: None of the above. | [E] |
<Instruct>: Given the context 'The amino acid sequence of p55CDC contains seven repeats homologous to the beta subunit of G proteins, and the highest degree of homology in these repeats was found with the Saccharomyces cerevisiae Cdc20 and Cdc4 proteins, which have been proposed to be involved in the formation of a functional bipolar mitotic spindle in yeast cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc; cdc20; cdc4]
<Options>: A: cdc4 (candida albicans sc5314) (aka scf ubiquitin ligase complex subunit)
B: p55cdc (homo sapiens) (aka cell division cycle 20)
C: cdc20 (xenopus laevis) (cell division cycle 20 s homeolog (xenopus laevis)) (aka cell division cycle 20 s homeolog)
D: cdc20c (homo sapiens) (aka fizzy and cell division cycle 20 related 1)
E: cdc20 (homo sapiens) (aka cell division cycle 20)
F: cdc20p (homo sapiens) (aka cell division cycle 20 pseudogene 1)
G: cdc4 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit cdc4)
H: p55cdc (mus musculus) (aka cell division cycle 20)
I: protein phosphatase 2a regulatory subunit cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
J: cdc20 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein cdc20)
K: cyclin-dependent kinase 4 homolog (caenorhabditis elegans) (aka cyclin-dependent kinase 4 homolog)
L: p5cdh (homo sapiens) (aka aldehyde dehydrogenase 4 family member a1)
M: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
N: cdc4 (homo sapiens) (aka f-box and wd repeat domain containing 7)
O: mcm4 (saccharomyces cerevisiae s288c) (aka mcm dna helicase complex subunit mcm4)
P: None of the above. | [B; J; G] |
<Instruct>: Given the context 'The amino acid sequence of p55CDC contains seven repeats homologous to the beta subunit of G proteins, and the highest degree of homology in these repeats was found with the Saccharomyces cerevisiae Cdc20 and Cdc4 proteins, which have been proposed to be involved in the formation of a functional bipolar mitotic spindle in yeast cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc; cdc20; cdc4]
<Options>: A: cdc20 (homo sapiens) (aka cell division cycle 20)
B: cdc4 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit cdc4)
C: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
D: p55cdc (mus musculus) (aka cell division cycle 20)
E: cdc4 (drosophila melanogaster) (aka archipelago)
F: cdc20[fizzy] (drosophila melanogaster) (aka fizzy)
G: cdc4 (candida albicans sc5314) (aka scf ubiquitin ligase complex subunit)
H: cdc20b (homo sapiens) (aka cell division cycle 20b)
I: cdc20 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein cdc20)
J: cdc20c (homo sapiens) (aka fizzy and cell division cycle 20 related 1)
K: protein phosphatase 2a regulatory subunit cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
L: mcm dna helicase complex subunit mcm4 (saccharomyces cerevisiae s288c) (aka mcm dna helicase complex subunit mcm4)
M: p55cdc (homo sapiens) (aka cell division cycle 20)
N: p5cd (homo sapiens) (aka aldehyde dehydrogenase 4 family member a1)
O: cyclin-dependent kinase 4 homolog (caenorhabditis elegans) (aka cyclin-dependent kinase 4 homolog)
P: None of the above. | [M; I; B] |
<Instruct>: Given the context 'The amino acid sequence of p55CDC contains seven repeats homologous to the beta subunit of G proteins, and the highest degree of homology in these repeats was found with the Saccharomyces cerevisiae Cdc20 and Cdc4 proteins, which have been proposed to be involved in the formation of a functional bipolar mitotic spindle in yeast cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc; cdc20; cdc4]
<Options>: A: cdc20[fizzy] (drosophila melanogaster) (aka fizzy)
B: protein phosphatase 2a regulatory subunit cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
C: cdc20b (homo sapiens) (aka cell division cycle 20b)
D: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
E: mcm dna helicase complex subunit mcm4 (saccharomyces cerevisiae s288c) (aka mcm dna helicase complex subunit mcm4)
F: cdc4 (drosophila melanogaster) (aka archipelago)
G: cdc4 (candida albicans sc5314) (aka scf ubiquitin ligase complex subunit)
H: p55cdc (homo sapiens) (aka cell division cycle 20)
I: p5cd (homo sapiens) (aka aldehyde dehydrogenase 4 family member a1)
J: cyclin-dependent kinase 4 homolog (caenorhabditis elegans) (aka cyclin-dependent kinase 4 homolog)
K: cdc20c (homo sapiens) (aka fizzy and cell division cycle 20 related 1)
L: p55cdc (mus musculus) (aka cell division cycle 20)
M: cdc4 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit cdc4)
N: cdc20 (homo sapiens) (aka cell division cycle 20)
O: None of the above. | [H; O; M] |
<Instruct>: Given the context 'The amino acid sequence of p55CDC contains seven repeats homologous to the beta subunit of G proteins, and the highest degree of homology in these repeats was found with the Saccharomyces cerevisiae Cdc20 and Cdc4 proteins, which have been proposed to be involved in the formation of a functional bipolar mitotic spindle in yeast cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc; cdc20; cdc4]
<Options>: A: cdc20c (homo sapiens) (aka fizzy and cell division cycle 20 related 1)
B: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
C: cdc20p (homo sapiens) (aka cell division cycle 20 pseudogene 1)
D: protein phosphatase 2a regulatory subunit cdc55 (saccharomyces cerevisiae s288c) (aka protein phosphatase 2a regulatory subunit cdc55)
E: mcm4 (saccharomyces cerevisiae s288c) (aka mcm dna helicase complex subunit mcm4)
F: p55cdc (homo sapiens) (aka cell division cycle 20)
G: cdc4 (drosophila melanogaster) (aka archipelago)
H: cdc20 (homo sapiens) (aka cell division cycle 20)
I: cdc4 (candida albicans sc5314) (aka scf ubiquitin ligase complex subunit)
J: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
K: cdc20 (xenopus laevis) (cell division cycle 20 s homeolog (xenopus laevis)) (aka cell division cycle 20 s homeolog)
L: cell division cycle 25c (homo sapiens) (aka cell division cycle 25c)
M: cdc20 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein cdc20)
N: cdc4 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit cdc4)
O: cdc24 (saccharomyces cerevisiae s288c) (aka rho family guanine nucleotide exchange factor cdc24)
P: None of the above. | [F; M; N] |
<Instruct>: Given the context 'The G beta repeat has been postulated to mediate protein-protein interactions and, in p55CDC, may modulate its association with a unique cell cycle protein kinase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p55cdc (homo sapiens) (aka cell division cycle 20)
B: cell division cycle 25c (homo sapiens) (aka cell division cycle 25c)
C: p55cdc (mus musculus) (aka cell division cycle 20)
D: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
E: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
F: None of the above. | [A] |
<Instruct>: Given the context 'These findings suggest that p55CDC is a component of the mammalian cell cycle mechanism.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p55cdc]
<Options>: A: p55cdc (xenopus tropicalis) (aka cell division cycle 20)
B: p5c (homo sapiens) (aka pyrroline-5-carboxylate reductase 1)
C: cell division cycle 25c (homo sapiens) (aka cell division cycle 25c)
D: p55cdc (homo sapiens) (aka cell division cycle 20)
E: p55cdc (mus musculus) (aka cell division cycle 20)
F: None of the above. | [D] |
<Instruct>: Given the context 'In the present study, serum from a patient with Sjögren's syndrome was used to identify a novel autoantigen which was designated Ge-1.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ge-1]
<Options>: A: esg1 (xenopus tropicalis) (transducin like enhancer of split 1 (xenopus tropicalis)) (aka transducin like enhancer of split 1)
B: ge-1 (xenopus tropicalis) (aka enhancer of mrna decapping 4)
C: gec1 (homo sapiens) (aka gaba type a receptor associated protein like 1)
D: ge-1 (xenopus laevis) (enhancer of mrna decapping 4 s homeolog (xenopus laevis)) (aka enhancer of mrna decapping 4 s homeolog)
E: ge1 (homo sapiens) (aka enhancer of mrna decapping 4)
F: None of the above. | [E] |
<Instruct>: Given the context 'Using the patient's serum, a 4.8-kb cDNA encoding Ge-1 was identified.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ge-1]
<Options>: A: gec1 (homo sapiens) (aka gaba type a receptor associated protein like 1)
B: ge-1 (homo sapiens) (aka enhancer of mrna decapping 4)
C: ge-1 (drosophila melanogaster) (aka ge-1)
D: esg1 (xenopus tropicalis) (transducin like enhancer of split 1 (xenopus tropicalis)) (aka transducin like enhancer of split 1)
E: ge-1 (xenopus tropicalis) (aka enhancer of mrna decapping 4)
F: None of the above. | [B] |
<Instruct>: Given the context 'Fusion proteins containing different portions of Ge-1 were used to identify a 58 amino acid immunoreactive region within the protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ge-1]
<Options>: A: ge-1 (xenopus tropicalis) (aka enhancer of mrna decapping 4)
B: ge-1 (xenopus laevis) (enhancer of mrna decapping 4 s homeolog (xenopus laevis)) (aka enhancer of mrna decapping 4 s homeolog)
C: ese-1 (homo sapiens) (aka e74 like ets transcription factor 3)
D: esg (xenopus tropicalis) (transducin like enhancer of split 1 (xenopus tropicalis)) (aka transducin like enhancer of split 1)
E: ge-1 (homo sapiens) (aka enhancer of mrna decapping 4)
F: None of the above. | [E] |
<Instruct>: Given the context 'The presence of the NLS motif within the immunoreactive region of Ge-1 and other nuclear autoantigens suggests that the NLS may be a target of human autoantibodies.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ge-1]
<Options>: A: ge-1 (xenopus laevis) (enhancer of mrna decapping 4 l homeolog (xenopus laevis)) (aka enhancer of mrna decapping 4 l homeolog)
B: gec1 (homo sapiens) (aka gaba type a receptor associated protein like 1)
C: ge-1 (drosophila melanogaster) (aka ge-1)
D: ge-1 (homo sapiens) (aka enhancer of mrna decapping 4)
E: ese-1 (homo sapiens) (aka e74 like ets transcription factor 3)
F: None of the above. | [D] |
<Instruct>: Given the context 'Like aquaporin 1 (AQP1, also known as CHIP, channel-forming integral membrane protein of 28 kDa), the deduced polypeptide has six putative transmembrane domains but lacks cysteines at the known mercury-sensitive sites.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aquaporin 1; aqp1; chip; channel-forming integral membrane protein of 28 kda]
<Options>: A: aqpx1 (homo sapiens) (aka aquaporin 11)
B: aqp0 (homo sapiens) (aka major intrinsic protein of lens fiber)
C: aquaporin-1 (xenopus laevis) (aquaporin 1 (colton blood group) s homeolog (xenopus laevis)) (aka aquaporin 1 (colton blood group) s homeolog)
D: chip (mus musculus) (aka stip1 homology and u-box containing protein 1)
E: chi (drosophila melanogaster) (chip (drosophila melanogaster)) (aka chip)
F: pic1 (homo sapiens) (aka small ubiquitin like modifier 1)
G: small integral membrane protein 28 (homo sapiens) (aka small integral membrane protein 28)
H: chip (homo sapiens) (aka stip1 homology and u-box containing protein 1)
I: aquaporin-1 (xenopus tropicalis) (aka aquaporin 1 (colton blood group))
J: transmembrane protein 128 (homo sapiens) (aka transmembrane protein 128)
K: c3orf28 (homo sapiens) (aka family with sequence similarity 162 member a)
L: aqp-1 (homo sapiens) (aka mindy lysine 48 deubiquitinase 4)
M: tmem28 (homo sapiens) (aka nalcn channel auxiliary factor 2)
N: aquaporin 1 (colton blood group) (homo sapiens) (aka aquaporin 1 (colton blood group))
O: katanin interacting protein (homo sapiens) (aka katanin interacting protein)
P: c1orf28 (homo sapiens) (aka cell division cycle 73)
Q: None of the above. | [N; N; N; N] |
<Instruct>: Given the context 'Like aquaporin 1 (AQP1, also known as CHIP, channel-forming integral membrane protein of 28 kDa), the deduced polypeptide has six putative transmembrane domains but lacks cysteines at the known mercury-sensitive sites.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aquaporin 1; aqp1; chip; channel-forming integral membrane protein of 28 kda]
<Options>: A: chip (homo sapiens) (aka stip1 homology and u-box containing protein 1)
B: pic1 (homo sapiens) (aka small ubiquitin like modifier 1)
C: aquaporin 1 (colton blood group) (homo sapiens) (aka aquaporin 1 (colton blood group))
D: aquaporin-1 (xenopus laevis) (aquaporin 1 (colton blood group) s homeolog (xenopus laevis)) (aka aquaporin 1 (colton blood group) s homeolog)
E: cxorf28 (homo sapiens) (aka long intergenic non-protein coding rna 1546)
F: aqp-1 (homo sapiens) (aka mindy lysine 48 deubiquitinase 4)
G: transmembrane protein 128 (homo sapiens) (aka transmembrane protein 128)
H: ctip (homo sapiens) (aka rb binding protein 8, endonuclease)
I: aqpx1 (homo sapiens) (aka aquaporin 11)
J: aquaporin1 (xenopus laevis) (aquaporin 1 (colton blood group) l homeolog (xenopus laevis)) (aka aquaporin 1 (colton blood group) l homeolog)
K: c4orf28 (homo sapiens) (aka parkin coregulated like)
L: chi (drosophila melanogaster) (chip (drosophila melanogaster)) (aka chip)
M: aquaporin1 (xenopus laevis) (aquaporin 1 (colton blood group) s homeolog (xenopus laevis)) (aka aquaporin 1 (colton blood group) s homeolog)
N: aqp0 (homo sapiens) (aka major intrinsic protein of lens fiber)
O: pic (homo sapiens) (aka solute carrier family 25 member 3)
P: tmem28 (homo sapiens) (aka nalcn channel auxiliary factor 2)
Q: tbc1 domain family member 28 (homo sapiens) (aka tbc1 domain family member 28)
R: None of the above. | [C; C; C; C] |
<Instruct>: Given the context 'Like aquaporin 1 (AQP1, also known as CHIP, channel-forming integral membrane protein of 28 kDa), the deduced polypeptide has six putative transmembrane domains but lacks cysteines at the known mercury-sensitive sites.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aquaporin 1; aqp1; chip; channel-forming integral membrane protein of 28 kda]
<Options>: A: aqp0 (homo sapiens) (aka major intrinsic protein of lens fiber)
B: chip (drosophila melanogaster) (stip1 homology and u-box containing protein 1 (drosophila melanogaster)) (aka stip1 homology and u-box containing protein 1)
C: transmembrane protein 128 (homo sapiens) (aka transmembrane protein 128)
D: putative ergosterol biosynthetic protein 28 homolog (caenorhabditis elegans) (aka putative ergosterol biosynthetic protein 28 homolog)
E: tbc1 domain family member 28 (homo sapiens) (aka tbc1 domain family member 28)
F: ctip (homo sapiens) (aka rb binding protein 8, endonuclease)
G: chip (mus musculus) (aka stip1 homology and u-box containing protein 1)
H: aquaporin-1 (xenopus laevis) (aquaporin 1 (colton blood group) s homeolog (xenopus laevis)) (aka aquaporin 1 (colton blood group) s homeolog)
I: c4orf28 (homo sapiens) (aka parkin coregulated like)
J: aqpx1 (homo sapiens) (aka aquaporin 11)
K: chip (homo sapiens) (aka stip1 homology and u-box containing protein 1)
L: aqp1 (homo sapiens) (aquaporin 1 (colton blood group) (homo sapiens)) (aka aquaporin 1 (colton blood group))
M: c3orf28 (homo sapiens) (aka family with sequence similarity 162 member a)
N: aquaporin-1 (xenopus tropicalis) (aka aquaporin 1 (colton blood group))
O: pic1 (homo sapiens) (aka small ubiquitin like modifier 1)
P: aqp-1 (homo sapiens) (aka mindy lysine 48 deubiquitinase 4)
Q: None of the above. | [L; L; L; L] |
<Instruct>: Given the context 'Like aquaporin 1 (AQP1, also known as CHIP, channel-forming integral membrane protein of 28 kDa), the deduced polypeptide has six putative transmembrane domains but lacks cysteines at the known mercury-sensitive sites.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aquaporin 1; aqp1; chip; channel-forming integral membrane protein of 28 kda]
<Options>: A: aqp0 (homo sapiens) (aka major intrinsic protein of lens fiber)
B: aquaporin1 (xenopus laevis) (aquaporin 1 (colton blood group) l homeolog (xenopus laevis)) (aka aquaporin 1 (colton blood group) l homeolog)
C: tmem28 (homo sapiens) (aka nalcn channel auxiliary factor 2)
D: aqp-1 (homo sapiens) (aka mindy lysine 48 deubiquitinase 4)
E: small integral membrane protein 28 (homo sapiens) (aka small integral membrane protein 28)
F: chi (drosophila melanogaster) (chip (drosophila melanogaster)) (aka chip)
G: katanin interacting protein (homo sapiens) (aka katanin interacting protein)
H: ctip (homo sapiens) (aka rb binding protein 8, endonuclease)
I: chip (arabidopsis thaliana) (aka carboxyl terminus of hsc70-interacting protein)
J: c1orf28 (homo sapiens) (aka cell division cycle 73)
K: pic (homo sapiens) (aka solute carrier family 25 member 3)
L: transmembrane protein 128 (homo sapiens) (aka transmembrane protein 128)
M: aqpx1 (homo sapiens) (aka aquaporin 11)
N: aquaporin 1 (colton blood group) (homo sapiens) (aka aquaporin 1 (colton blood group))
O: aquaporin-1 (xenopus laevis) (aquaporin 1 (colton blood group) s homeolog (xenopus laevis)) (aka aquaporin 1 (colton blood group) s homeolog)
P: putative ergosterol biosynthetic protein 28 homolog (caenorhabditis elegans) (aka putative ergosterol biosynthetic protein 28 homolog)
Q: None of the above. | [N; N; N; N] |
<Instruct>: Given the context 'Its distinctive expression pattern implicates this fourth mammalian member of the aquaporin water channel family (designated gene symbol, AQP4) as the osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aqp4]
<Options>: A: aqp4 (oryctolagus cuniculus) (aka aquaporin 4)
B: aqp4 (danio rerio) (aka aquaporin 4)
C: aqp4 (bos taurus) (aka aquaporin 4)
D: aqp4 (mus musculus) (aka aquaporin 4)
E: aqp4 (homo sapiens) (aka aquaporin 4)
F: None of the above. | [E] |
<Instruct>: Given the context 'Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin]
<Options>: A: arginine vasopressin (homo sapiens) (aka arginine vasopressin)
B: avp (rattus norvegicus) (aka arginine vasopressin)
C: vasotocin (xenopus laevis) (arginine vasopressin s homeolog (xenopus laevis)) (aka arginine vasopressin s homeolog)
D: arginine vasopressin (xenopus tropicalis) (aka arginine vasopressin)
E: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
F: None of the above. | [A] |
<Instruct>: Given the context 'Water excretion by the kidney is regulated by the peptide hormone vasopressin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin]
<Options>: A: avp (homo sapiens) (arginine vasopressin (homo sapiens)) (aka arginine vasopressin)
B: vasopressin (xenopus laevis) (arginine vasopressin s homeolog (xenopus laevis)) (aka arginine vasopressin s homeolog)
C: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
D: arginine vasopressin (rattus norvegicus) (aka arginine vasopressin)
E: vasopressin (sus scrofa) (aka vasopressin)
F: None of the above. | [A] |
<Instruct>: Given the context 'Vasopressin increases the water permeability of the renal collecting duct cells, allowing more water to be reabsorbed from collecting duct urine to blood.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin]
<Options>: A: vasotocin (xenopus laevis) (arginine vasopressin s homeolog (xenopus laevis)) (aka arginine vasopressin s homeolog)
B: avp (homo sapiens) (arginine vasopressin (homo sapiens)) (aka arginine vasopressin)
C: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
D: vasopressin (sus scrofa) (aka vasopressin)
E: avp (rattus norvegicus) (aka arginine vasopressin)
F: None of the above. | [B] |
<Instruct>: Given the context 'Recently, a molecular water channel (AQP-CD) has been cloned whose expression appears to be limited to the collecting duct.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aqp-cd]
<Options>: A: aqp-cd (homo sapiens) (aka aquaporin 2)
B: aqp-cd (xenopus laevis) (aquaporin 2 s homeolog (xenopus laevis)) (aka aquaporin 2 s homeolog)
C: aqp-cd (oryctolagus cuniculus) (aka aquaporin 2)
D: aqp-cd (mus musculus) (aka aquaporin 2)
E: aqp-cd (xenopus tropicalis) (aka aquaporin 2)
F: None of the above. | [A] |
<Instruct>: Given the context 'Recently, a molecular water channel (AQP-CD) has been cloned whose expression appears to be limited to the collecting duct.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aqp-cd]
<Options>: A: aqp-cd (xenopus tropicalis) (aka aquaporin 2)
B: aqp-cd (oryctolagus cuniculus) (aka aquaporin 2)
C: aqp-cd (xenopus laevis) (aquaporin 2 s homeolog (xenopus laevis)) (aka aquaporin 2 s homeolog)
D: aqp-cd (mus musculus) (aka aquaporin 2)
E: None of the above. | [E] |
<Instruct>: Given the context 'Here, we test the hypothesis that vasopressin increases cellular water permeability by inducing exocytosis of AQP-CD-laden vesicles, transferring water channels from IVs to APM.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin; aqp-cd]
<Options>: A: vasotocin (xenopus laevis) (arginine vasopressin s homeolog (xenopus laevis)) (aka arginine vasopressin s homeolog)
B: aqp-cd (homo sapiens) (aka aquaporin 2)
C: avp (rattus norvegicus) (aka arginine vasopressin)
D: aqpcd (xenopus laevis) (aquaporin 2 s homeolog (xenopus laevis)) (aka aquaporin 2 s homeolog)
E: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
F: aqpcd (xenopus laevis) (aquaporin 2 l homeolog (xenopus laevis)) (aka aquaporin 2 l homeolog)
G: aqp-2 (oryctolagus cuniculus) (aka aquaporin 2)
H: arginine vasopressin (xenopus tropicalis) (aka arginine vasopressin)
I: aqp-cd (mus musculus) (aka aquaporin 2)
J: vp (homo sapiens) (arginine vasopressin (homo sapiens)) (aka arginine vasopressin)
K: None of the above. | [J; B] |
<Instruct>: Given the context 'Here, we test the hypothesis that vasopressin increases cellular water permeability by inducing exocytosis of AQP-CD-laden vesicles, transferring water channels from IVs to APM.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin; aqp-cd]
<Options>: A: vasopressin (sus scrofa) (aka vasopressin)
B: avp (rattus norvegicus) (aka arginine vasopressin)
C: aqp-cd (homo sapiens) (aka aquaporin 2)
D: arginine vasopressin (homo sapiens) (aka arginine vasopressin)
E: arginine vasopressin (xenopus tropicalis) (aka arginine vasopressin)
F: aqp-cd (mus musculus) (aka aquaporin 2)
G: aqp-cd (oryctolagus cuniculus) (aka aquaporin 2)
H: aqp-cd (xenopus tropicalis) (aka aquaporin 2)
I: aqp-cd (xenopus laevis) (aquaporin 2 l homeolog (xenopus laevis)) (aka aquaporin 2 l homeolog)
J: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
K: None of the above. | [D; C] |
<Instruct>: Given the context 'Rat collecting ducts were perfused in vitro to determine water permeability and subcellular distribution of AQP-CD in the same tubules.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aqp-cd]
<Options>: A: aqp-cd (homo sapiens) (aka aquaporin 2)
B: aqp-cd (oryctolagus cuniculus) (aka aquaporin 2)
C: aqp-cd (mus musculus) (aka aquaporin 2)
D: aqpcd (xenopus tropicalis) (aka aquaporin 2)
E: aqpcd (xenopus laevis) (aquaporin 2 s homeolog (xenopus laevis)) (aka aquaporin 2 s homeolog)
F: None of the above. | [A] |
<Instruct>: Given the context 'The collecting ducts were fixed for immunoelectron microscopy before, during, and after exposure to vasopressin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin]
<Options>: A: arginine vasopressin (xenopus tropicalis) (aka arginine vasopressin)
B: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
C: vp (homo sapiens) (arginine vasopressin (homo sapiens)) (aka arginine vasopressin)
D: vasopressin (sus scrofa) (aka vasopressin)
E: arginine vasopressin (rattus norvegicus) (aka arginine vasopressin)
F: None of the above. | [C] |
<Instruct>: Given the context 'Vasopressin exposure induced increases in water permeability and the absolute labeling density of AQP-CD in the APM.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin; aqp-cd]
<Options>: A: aqp-cd (xenopus laevis) (aquaporin 2 l homeolog (xenopus laevis)) (aka aquaporin 2 l homeolog)
B: aqp-cd (mus musculus) (aka aquaporin 2)
C: vasopressin (sus scrofa) (aka vasopressin)
D: aqp-cd (homo sapiens) (aka aquaporin 2)
E: arginine vasopressin (xenopus tropicalis) (aka arginine vasopressin)
F: avp (rattus norvegicus) (aka arginine vasopressin)
G: aqp-cd (xenopus tropicalis) (aka aquaporin 2)
H: aqp-cd (xenopus laevis) (aquaporin 2 s homeolog (xenopus laevis)) (aka aquaporin 2 s homeolog)
I: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
J: arginine vasopressin (homo sapiens) (aka arginine vasopressin)
K: None of the above. | [J; D] |
<Instruct>: Given the context 'Vasopressin exposure induced increases in water permeability and the absolute labeling density of AQP-CD in the APM.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vasopressin; aqp-cd]
<Options>: A: vasopressin (sus scrofa) (aka vasopressin)
B: aqp-cd (oryctolagus cuniculus) (aka aquaporin 2)
C: aqp-cd (xenopus tropicalis) (aka aquaporin 2)
D: aqpcd (xenopus laevis) (aquaporin 2 s homeolog (xenopus laevis)) (aka aquaporin 2 s homeolog)
E: aqp-cd (homo sapiens) (aka aquaporin 2)
F: aqp-cd (mus musculus) (aka aquaporin 2)
G: arginine vasopressin (rattus norvegicus) (aka arginine vasopressin)
H: vasopressin (xenopus laevis) (arginine vasopressin s homeolog (xenopus laevis)) (aka arginine vasopressin s homeolog)
I: avp (homo sapiens) (arginine vasopressin (homo sapiens)) (aka arginine vasopressin)
J: vasopressin (xenopus laevis) (arginine vasopressin l homeolog (xenopus laevis)) (aka arginine vasopressin l homeolog)
K: None of the above. | [I; E] |
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