instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Here we show that Yaf2 also binds to the Myc protein in vivo and in vitro.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yaf2; myc]
<Options>: A: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
B: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
C: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
D: yaf5 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein pex22)
E: mycl (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
F: yaf1 (saccharomyces cerevisiae s288c) (aka oleate-activated transcription factor oaf1)
G: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
H: yaf2-b (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis)) (aka yy1 associated factor 2 s homeolog)
I: yaf2 (xenopus tropicalis) (aka yy1 associated factor 2)
J: yaf2 (homo sapiens) (aka yy1 associated factor 2)
K: None of the above. | [J; G] |
<Instruct>: Given the context 'Here we show that Yaf2 also binds to the Myc protein in vivo and in vitro.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yaf2; myc]
<Options>: A: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
B: yaf5 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein pex22)
C: yaf2 (bos taurus) (aka yy1 associated factor 2)
D: mycl (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
E: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: yaf2 (homo sapiens) (aka yy1 associated factor 2)
G: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
H: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
I: yaf2-a (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis)) (aka yy1 associated factor 2 s homeolog)
J: yaf2 (sus scrofa) (aka yy1 associated factor 2)
K: None of the above. | [F; G] |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mycn; yaf2; myc]
<Options>: A: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
B: yaf2 (bos taurus) (aka yy1 associated factor 2)
C: yaf2 (homo sapiens) (aka yy1 associated factor 2)
D: mycn proto-oncogene, bhlh transcription factor (rattus norvegicus) (aka mycn proto-oncogene, bhlh transcription factor)
E: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
G: yaf2 (sus scrofa) (aka yy1 associated factor 2)
H: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
I: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
J: mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis) (aka mycn proto-oncogene, bhlh transcription factor)
K: yaf1 (saccharomyces cerevisiae s288c) (aka oleate-activated transcription factor oaf1)
L: n-myc (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
M: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
N: yaf2 (xenopus laevis) (aka yy1 associated factor 2 s homeolog)
O: None of the above. | [L; C; M] |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mycn; yaf2; myc]
<Options>: A: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
B: yaf2 (sus scrofa) (aka yy1 associated factor 2)
C: yaf2 (xenopus laevis) (aka yy1 associated factor 2 s homeolog)
D: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
E: yaf2 (bos taurus) (aka yy1 associated factor 2)
F: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
G: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
H: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
I: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
J: mycn proto-oncogene, bhlh transcription factor (rattus norvegicus) (aka mycn proto-oncogene, bhlh transcription factor)
K: yaf2 (homo sapiens) (aka yy1 associated factor 2)
L: yaf1 (saccharomyces cerevisiae s288c) (aka oleate-activated transcription factor oaf1)
M: mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis) (aka mycn proto-oncogene, bhlh transcription factor)
N: None of the above. | [N; K; A] |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mycn; yaf2; myc]
<Options>: A: yaf1 (homo sapiens) (aka histone deacetylase 2)
B: yaf2-a (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis)) (aka yy1 associated factor 2 s homeolog)
C: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
D: mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis) (aka mycn proto-oncogene, bhlh transcription factor)
E: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
F: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
G: mycn proto-oncogene, bhlh transcription factor (rattus norvegicus) (aka mycn proto-oncogene, bhlh transcription factor)
H: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
I: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
J: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
K: mycn, opposite strand (mus musculus) (aka mycn, opposite strand)
L: mycn proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
M: yaf2 (homo sapiens) (aka yy1 associated factor 2)
N: yaf2 (xenopus tropicalis) (aka yy1 associated factor 2)
O: yaf2 (bos taurus) (aka yy1 associated factor 2)
P: None of the above. | [L; M; C] |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mycn; yaf2; myc]
<Options>: A: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
B: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
C: mycn proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
D: mycn, opposite strand (mus musculus) (aka mycn, opposite strand)
E: mycn proto-oncogene, bhlh transcription factor (rattus norvegicus) (aka mycn proto-oncogene, bhlh transcription factor)
F: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
G: mycl proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
H: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
I: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
J: yaf2-b (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis)) (aka yy1 associated factor 2 s homeolog)
K: yaf2 (xenopus tropicalis) (aka yy1 associated factor 2)
L: yaf2 (homo sapiens) (aka yy1 associated factor 2)
M: yaf5 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein pex22)
N: yaf1 (saccharomyces cerevisiae s288c) (aka oleate-activated transcription factor oaf1)
O: mycn (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
P: None of the above. | [C; L; I] |
<Instruct>: Given the context 'This differential influence on two members of the Myc family gives insight into a new mechanism to modulate the biological activities of Myc transcription factors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [myc]
<Options>: A: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
B: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
C: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
D: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
E: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
F: None of the above. | [C] |
<Instruct>: Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [keratinocyte growth factor receptor; bek; fibroblast growth factor receptor 2]
<Options>: A: elk1 (bos taurus) (aka ets transcription factor elk1)
B: blk (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
C: hbgfr (homo sapiens) (aka fibroblast growth factor receptor 1)
D: fibroblast growth factor receptor 1 (homo sapiens) (aka fibroblast growth factor receptor 1)
E: fibroblast growth factor receptor 3 (homo sapiens) (aka fibroblast growth factor receptor 3)
F: bek (xenopus tropicalis) (aka fibroblast growth factor receptor 2)
G: dek proto-oncogene (bos taurus) (aka dek proto-oncogene)
H: kgfr (homo sapiens) (aka fibroblast growth factor receptor 2)
I: trkb (homo sapiens) (aka neurotrophic receptor tyrosine kinase 2)
J: fibroblast growth factor receptor 2 (sus scrofa) (aka fibroblast growth factor receptor 2)
K: None of the above. | [H; H; H] |
<Instruct>: Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [keratinocyte growth factor receptor; bek; fibroblast growth factor receptor 2]
<Options>: A: hbgfr (homo sapiens) (aka fibroblast growth factor receptor 1)
B: bek (xenopus tropicalis) (aka fibroblast growth factor receptor 2)
C: fibroblast growth factor receptor 1 (homo sapiens) (aka fibroblast growth factor receptor 1)
D: blk (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
E: fibroblast growth factor receptor 3 (homo sapiens) (aka fibroblast growth factor receptor 3)
F: trkb (homo sapiens) (aka neurotrophic receptor tyrosine kinase 2)
G: elk1 (bos taurus) (aka ets transcription factor elk1)
H: fibroblast growth factor receptor 2 (sus scrofa) (aka fibroblast growth factor receptor 2)
I: dek proto-oncogene (bos taurus) (aka dek proto-oncogene)
J: None of the above. | [J; J; J] |
<Instruct>: Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [keratinocyte growth factor receptor; bek; fibroblast growth factor receptor 2]
<Options>: A: bek (xenopus tropicalis) (aka fibroblast growth factor receptor 2)
B: hbgfr (homo sapiens) (aka fibroblast growth factor receptor 1)
C: blk proto-oncogene, src family tyrosine kinase (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
D: kgfr (homo sapiens) (aka fibroblast growth factor receptor 2)
E: fibroblast growth factor receptor 2 (sus scrofa) (aka fibroblast growth factor receptor 2)
F: bek (gallus gallus) (aka fibroblast growth factor receptor 2)
G: fgfr-1 (homo sapiens) (aka fibroblast growth factor receptor 1)
H: trkb (homo sapiens) (aka neurotrophic receptor tyrosine kinase 2)
I: fibroblast growth factor receptor 3 (homo sapiens) (aka fibroblast growth factor receptor 3)
J: dek proto-oncogene (bos taurus) (aka dek proto-oncogene)
K: None of the above. | [D; D; D] |
<Instruct>: Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [keratinocyte growth factor receptor; bek; fibroblast growth factor receptor 2]
<Options>: A: bek (mus musculus) (aka fibroblast growth factor receptor 2)
B: fibroblast growth factor receptor 3 (homo sapiens) (aka fibroblast growth factor receptor 3)
C: kgfr (homo sapiens) (aka fibroblast growth factor receptor 2)
D: blk proto-oncogene, src family tyrosine kinase (bos taurus) (aka blk proto-oncogene, src family tyrosine kinase)
E: dek proto-oncogene (bos taurus) (aka dek proto-oncogene)
F: trkb (homo sapiens) (aka neurotrophic receptor tyrosine kinase 2)
G: fibroblast growth factor receptor 1 (homo sapiens) (aka fibroblast growth factor receptor 1)
H: fibroblast growth factor receptor 2 (sus scrofa) (aka fibroblast growth factor receptor 2)
I: ekb (homo sapiens) (aka choline kinase beta)
J: hbgfr (homo sapiens) (aka fibroblast growth factor receptor 1)
K: None of the above. | [C; C; C] |
<Instruct>: Given the context 'Both serine and tyrosine phosphatase activities were completely abolished by mutagenesis of a single cysteine residue conserved in VH1 and the VH1-related (VHR) human protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vh1-related (vhr) human protein]
<Options>: A: vhr (homo sapiens) (aka dual specificity phosphatase 3)
B: vh3 (homo sapiens) (aka immunoglobulin heavy variable 3-75 (pseudogene))
C: vhx (homo sapiens) (aka dual specificity phosphatase 22)
D: vh (homo sapiens) (solute carrier family 7 member 4 (homo sapiens)) (aka solute carrier family 7 member 4)
E: vh5 (homo sapiens) (aka immunoglobulin heavy variable 5-78 (pseudogene))
F: None of the above. | [A] |
<Instruct>: Given the context 'These properties suggest that VHR is capable of regulating intracellular events mediated by both tyrosine and serine phosphorylation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [vhr]
<Options>: A: vhr2 (saccharomyces cerevisiae s288c) (aka vhr2p)
B: vhr (homo sapiens) (aka dual specificity phosphatase 3)
C: vhx (homo sapiens) (aka dual specificity phosphatase 22)
D: vho (homo sapiens) (aka growth differentiation factor 11)
E: vhr1 (saccharomyces cerevisiae s288c) (aka vhr1p)
F: None of the above. | [B] |
<Instruct>: Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ah receptor nuclear translocator; arnt; ah receptor]
<Options>: A: aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis) (aka aryl hydrocarbon receptor nuclear translocator)
B: aryl hydrocarbon receptor nuclear translocator (gallus gallus) (aka aryl hydrocarbon receptor nuclear translocator)
C: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
D: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
E: arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
F: ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens)) (aka aryl hydrocarbon receptor repressor)
G: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
H: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
I: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
J: arno (homo sapiens) (aka cytohesin 2)
K: aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans) (aka aryl hydrocarbon receptor nuclear translocator homolog)
L: arno3 (homo sapiens) (aka cytohesin 3)
M: arnt (drosophila melanogaster) (aka tango)
N: None of the above. | [E; E; I] |
<Instruct>: Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ah receptor nuclear translocator; arnt; ah receptor]
<Options>: A: arno3 (homo sapiens) (aka cytohesin 3)
B: basic helix-loop-helix arnt like 1 (homo sapiens) (aka basic helix-loop-helix arnt like 1)
C: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
D: aryl hydrocarbon receptor nuclear translocator (gallus gallus) (aka aryl hydrocarbon receptor nuclear translocator)
E: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
F: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
G: arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
H: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
I: aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans) (aka aryl hydrocarbon receptor nuclear translocator homolog)
J: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
K: aryl hydrocarbon receptor nuclear translocator 2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
L: arnt (drosophila melanogaster) (aka tango)
M: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
N: None of the above. | [G; G; E] |
<Instruct>: Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ah receptor nuclear translocator; arnt; ah receptor]
<Options>: A: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
B: aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis) (aka aryl hydrocarbon receptor nuclear translocator)
C: arno3 (homo sapiens) (aka cytohesin 3)
D: tango (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
E: aryl hydrocarbon receptor nuclear translocator (gallus gallus) (aka aryl hydrocarbon receptor nuclear translocator)
F: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
G: arno (homo sapiens) (aka cytohesin 2)
H: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
I: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
J: aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans) (aka aryl hydrocarbon receptor nuclear translocator homolog)
K: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
L: arntl (homo sapiens) (aka basic helix-loop-helix arnt like 1)
M: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
N: None of the above. | [D; D; M] |
<Instruct>: Given the context 'The Ah (dioxin) receptor binds a number of widely disseminated environmental pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polycyclic aromatic hydrocarbons, and mediates their carcinogenic effects.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ah (dioxin) receptor]
<Options>: A: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
B: aryl hydrocarbon receptor protein 1 (caenorhabditis elegans) (aka aryl hydrocarbon receptor protein 1)
C: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
D: aryl hydrocarbon receptor 1a (danio rerio) (aka aryl hydrocarbon receptor 1a)
E: aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans) (aka aryl hydrocarbon receptor nuclear translocator homolog)
F: None of the above. | [C] |
<Instruct>: Given the context 'The ligand-bound receptor activates Cyp 1a1 gene transcription through interaction with specific DNA sequences, termed xenobiotic responsive elements (XREs).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cyp 1a1]
<Options>: A: cyp1 (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
B: cyp17a1 (homo sapiens) (aka cytochrome p450 family 17 subfamily a member 1)
C: cytochrome p450 family 1 subfamily a member 1 (bos taurus) (aka cytochrome p450 family 1 subfamily a member 1)
D: 1a1 (homo sapiens) (aka solute carrier family 45 member 2)
E: cyp1alpha (homo sapiens) (aka cytochrome p450 family 27 subfamily b member 1)
F: None of the above. | [A] |
<Instruct>: Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ah receptor nuclear translocator; arnt; ah receptor]
<Options>: A: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
B: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
C: aryl hydrocarbon receptor nuclear translocator (rattus norvegicus) (aka aryl hydrocarbon receptor nuclear translocator)
D: arno (homo sapiens) (aka cytohesin 2)
E: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
F: arno3 (homo sapiens) (aka cytohesin 3)
G: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
H: ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens)) (aka aryl hydrocarbon receptor repressor)
I: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
J: aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis) (aka aryl hydrocarbon receptor nuclear translocator)
K: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
L: aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans) (aka aryl hydrocarbon receptor nuclear translocator homolog)
M: None of the above. | [K; K; G] |
<Instruct>: Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ah receptor nuclear translocator; arnt; ah receptor]
<Options>: A: arno3 (homo sapiens) (aka cytohesin 3)
B: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
C: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
D: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
E: aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis) (aka aryl hydrocarbon receptor nuclear translocator)
F: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
G: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
H: ahr (homo sapiens) (aka aryl hydrocarbon receptor)
I: aryl hydrocarbon receptor nuclear translocator (rattus norvegicus) (aka aryl hydrocarbon receptor nuclear translocator)
J: arno (homo sapiens) (aka cytohesin 2)
K: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
L: aryl hydrocarbon receptor repressor (homo sapiens) (aka aryl hydrocarbon receptor repressor)
M: arnt (drosophila melanogaster) (aka tango)
N: aryl hydrocarbon receptor nuclear translocator (gallus gallus) (aka aryl hydrocarbon receptor nuclear translocator)
O: None of the above. | [F; F; H] |
<Instruct>: Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ah receptor nuclear translocator; arnt; ah receptor]
<Options>: A: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
B: aryl hydrocarbon receptor repressor (homo sapiens) (aka aryl hydrocarbon receptor repressor)
C: aryl hydrocarbon receptor nuclear translocator (rattus norvegicus) (aka aryl hydrocarbon receptor nuclear translocator)
D: aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans) (aka aryl hydrocarbon receptor nuclear translocator homolog)
E: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
F: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
G: arno (homo sapiens) (aka cytohesin 2)
H: arnt (drosophila melanogaster) (aka tango)
I: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
J: arntl (homo sapiens) (aka basic helix-loop-helix arnt like 1)
K: aryl hydrocarbon receptor nuclear translocator (gallus gallus) (aka aryl hydrocarbon receptor nuclear translocator)
L: arnt1 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
M: aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis) (aka aryl hydrocarbon receptor nuclear translocator)
N: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
O: None of the above. | [L; L; E] |
<Instruct>: Given the context 'Arnt is now shown to be a structural component of the XRE binding form of the Ah receptor.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [arnt; ah receptor]
<Options>: A: arno (homo sapiens) (aka cytohesin 2)
B: ahr (homo sapiens) (aka aryl hydrocarbon receptor)
C: arnt1 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
D: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
E: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
F: arnt (drosophila melanogaster) (aka tango)
G: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
H: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
I: ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens)) (aka aryl hydrocarbon receptor repressor)
J: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
K: None of the above. | [C; B] |
<Instruct>: Given the context 'Arnt is now shown to be a structural component of the XRE binding form of the Ah receptor.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [arnt; ah receptor]
<Options>: A: arnt (drosophila melanogaster) (aka tango)
B: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
C: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
D: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
E: ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens)) (aka aryl hydrocarbon receptor repressor)
F: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
G: arnt1 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
H: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
I: arno (homo sapiens) (aka cytohesin 2)
J: None of the above. | [G; J] |
<Instruct>: Given the context 'Arnt is now shown to be a structural component of the XRE binding form of the Ah receptor.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [arnt; ah receptor]
<Options>: A: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
B: arno (homo sapiens) (aka cytohesin 2)
C: arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
D: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
E: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
F: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
G: basic helix-loop-helix arnt like 1 (homo sapiens) (aka basic helix-loop-helix arnt like 1)
H: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
I: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
J: ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens)) (aka aryl hydrocarbon receptor repressor)
K: None of the above. | [C; I] |
<Instruct>: Given the context 'Furthermore, Arnt and the ligand-binding subunit of the receptor were extracted as a complex from the nuclei of cells treated with ligand.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [arnt]
<Options>: A: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
B: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
C: arno3 (homo sapiens) (aka cytohesin 3)
D: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
E: arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
F: None of the above. | [E] |
<Instruct>: Given the context 'Arnt contains a basic helix-loop-helix motif, which may be responsible for interacting with both the XRE and the ligand-binding subunit.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [arnt]
<Options>: A: arno3 (homo sapiens) (aka cytohesin 3)
B: arntl (homo sapiens) (aka basic helix-loop-helix arnt like 1)
C: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
D: arnt (drosophila melanogaster) (aka tango)
E: arnt1 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
F: None of the above. | [E] |
<Instruct>: Given the context 'Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [saf-a]
<Options>: A: scf ubiquitin ligase complex subunit saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
B: saf-b (homo sapiens) (aka scaffold attachment factor b)
C: saf-a (drosophila melanogaster) (aka uncharacterized protein)
D: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
E: saf-a (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
F: None of the above. | [E] |
<Instruct>: Given the context 'We identified four proteins in nuclear extracts from HeLa cells which specifically bind to a scaffold attachment region (SAR) element from the human genome.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [scaffold attachment region; sar]
<Options>: A: saraf (homo sapiens) (aka store-operated calcium entry associated regulatory factor)
B: clk4 associating serine/arginine rich protein (bos taurus) (aka clk4 associating serine/arginine rich protein)
C: sra (drosophila melanogaster) (sarah (drosophila melanogaster)) (aka sarah)
D: clk4-associating serine/arginine rich protein (xenopus tropicalis) (aka clk4-associating serine/arginine rich protein)
E: sarp (homo sapiens) (aka ankyrin repeat domain 42)
F: sar (mus musculus) (sarcosinemia autosomal recessive (mus musculus)) (aka sarcosinemia autosomal recessive)
G: scaffold protein involved in dna repair (sus scrofa) (aka scaffold protein involved in dna repair)
H: srr1 domain containing (sus scrofa) (aka srr1 domain containing)
I: small regulatory polypeptide of amino acid response (sus scrofa) (aka small regulatory polypeptide of amino acid response)
J: clk4-associating serine/arginine rich protein (mus musculus) (aka clk4-associating serine/arginine rich protein)
K: None of the above. | [K; K] |
<Instruct>: Given the context 'We identified four proteins in nuclear extracts from HeLa cells which specifically bind to a scaffold attachment region (SAR) element from the human genome.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [scaffold attachment region; sar]
<Options>: A: clk4 associating serine/arginine rich protein (sus scrofa) (aka clk4 associating serine/arginine rich protein)
B: receptor associated protein of the synapse (sus scrofa) (aka receptor associated protein of the synapse)
C: steroid receptor associated and regulated protein (sus scrofa) (aka steroid receptor associated and regulated protein)
D: sar1a (homo sapiens) (aka secretion associated ras related gtpase 1a)
E: sar1 (arabidopsis thaliana) (suppressor of auxin resistance1 (arabidopsis thaliana)) (aka suppressor of auxin resistance1)
F: sarp (homo sapiens) (aka ankyrin repeat domain 42)
G: small regulatory polypeptide of amino acid response (sus scrofa) (aka small regulatory polypeptide of amino acid response)
H: clk4-associating serine/arginine rich protein (xenopus tropicalis) (aka clk4-associating serine/arginine rich protein)
I: serine/threonine kinase receptor associated protein (sus scrofa) (aka serine/threonine kinase receptor associated protein)
J: saraf (homo sapiens) (aka store-operated calcium entry associated regulatory factor)
K: None of the above. | [K; K] |
<Instruct>: Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [saf-a; scaffold attachment factor a; sar]
<Options>: A: saf-a (drosophila melanogaster) (aka uncharacterized protein)
B: scaffold attachment factor b (xenopus tropicalis) (aka scaffold attachment factor b)
C: sar1 (arabidopsis thaliana) (suppressor of auxin resistance1 (arabidopsis thaliana)) (aka suppressor of auxin resistance1)
D: sra (drosophila melanogaster) (sarah (drosophila melanogaster)) (aka sarah)
E: saf-a2 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u like 2)
F: saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
G: saf (homo sapiens) (aka fas antisense rna 1)
H: uv stimulated scaffold protein a (xenopus tropicalis) (aka uv stimulated scaffold protein a)
I: saf-a (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
J: sarp (homo sapiens) (aka ankyrin repeat domain 42)
K: sar (mus musculus) (sarcosinemia autosomal recessive (mus musculus)) (aka sarcosinemia autosomal recessive)
L: uv-stimulated scaffold protein a homolog (caenorhabditis elegans) (aka uv-stimulated scaffold protein a homolog)
M: chromatin assembly factor 1 subunit a (sus scrofa) (aka chromatin assembly factor 1 subunit a)
N: small regulatory polypeptide of amino acid response (sus scrofa) (aka small regulatory polypeptide of amino acid response)
O: None of the above. | [I; I; O] |
<Instruct>: Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [saf-a; scaffold attachment factor a; sar]
<Options>: A: chromatin assembly factor 1 subunit a (sus scrofa) (aka chromatin assembly factor 1 subunit a)
B: sarnp (homo sapiens) (aka sap domain containing ribonucleoprotein)
C: sara1 (homo sapiens) (aka secretion associated ras related gtpase 1a)
D: small regulatory polypeptide of amino acid response (homo sapiens) (aka small regulatory polypeptide of amino acid response)
E: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
F: scaffold attachment factor b (xenopus tropicalis) (aka scaffold attachment factor b)
G: saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
H: saf-b (homo sapiens) (aka scaffold attachment factor b)
I: saf-a (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
J: saf-a (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
K: sar (mus musculus) (sarcosinemia autosomal recessive (mus musculus)) (aka sarcosinemia autosomal recessive)
L: uv stimulated scaffold protein a (sus scrofa) (aka uv stimulated scaffold protein a)
M: saraf (homo sapiens) (aka store-operated calcium entry associated regulatory factor)
N: uv-stimulated scaffold protein a homolog (caenorhabditis elegans) (aka uv-stimulated scaffold protein a homolog)
O: None of the above. | [J; J; O] |
<Instruct>: Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [saf-a; scaffold attachment factor a; sar]
<Options>: A: nucleosome assembly factor asf1 (saccharomyces cerevisiae s288c) (aka nucleosome assembly factor asf1)
B: sra (drosophila melanogaster) (sarah (drosophila melanogaster)) (aka sarah)
C: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
D: small regulatory polypeptide of amino acid response (sus scrofa) (aka small regulatory polypeptide of amino acid response)
E: saf-a2 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u like 2)
F: saf-a (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
G: scaffold attachment factor b (xenopus tropicalis) (aka scaffold attachment factor b)
H: saf-a (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
I: saf-a (drosophila melanogaster) (aka uncharacterized protein)
J: sar (mus musculus) (sarcosinemia autosomal recessive (mus musculus)) (aka sarcosinemia autosomal recessive)
K: saf (homo sapiens) (aka fas antisense rna 1)
L: chromatin assembly factor 1 subunit a (sus scrofa) (aka chromatin assembly factor 1 subunit a)
M: sara1 (homo sapiens) (aka secretion associated ras related gtpase 1a)
N: saraf (homo sapiens) (aka store-operated calcium entry associated regulatory factor)
O: None of the above. | [F; F; O] |
<Instruct>: Given the context 'SAF-A is an abundant nuclear protein and a constituent of the nuclear matrix and scaffold.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [saf-a]
<Options>: A: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
B: saf-a (drosophila melanogaster) (aka uncharacterized protein)
C: saf-a (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
D: saf-b (homo sapiens) (aka scaffold attachment factor b)
E: saf-a (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
F: None of the above. | [C] |
<Instruct>: Given the context 'SAF-A binds at multiple sites to the human SAR element; competition studies with synthetic polynucleotides indicate that these sites most probably reside in the multitude of A/T-stretches which are distributed throughout this element.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [saf-a; sar]
<Options>: A: saf-b (homo sapiens) (aka scaffold attachment factor b)
B: saf-a (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
C: sarp (homo sapiens) (aka ankyrin repeat domain 42)
D: sra (drosophila melanogaster) (sarah (drosophila melanogaster)) (aka sarah)
E: sar (mus musculus) (sarcosinemia autosomal recessive (mus musculus)) (aka sarcosinemia autosomal recessive)
F: saraf (homo sapiens) (aka store-operated calcium entry associated regulatory factor)
G: saf-a2 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u like 2)
H: saf (homo sapiens) (aka fas antisense rna 1)
I: sar1 (arabidopsis thaliana) (suppressor of auxin resistance1 (arabidopsis thaliana)) (aka suppressor of auxin resistance1)
J: safa (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
K: None of the above. | [J; K] |
<Instruct>: Given the context 'SAF-A binds at multiple sites to the human SAR element; competition studies with synthetic polynucleotides indicate that these sites most probably reside in the multitude of A/T-stretches which are distributed throughout this element.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [saf-a; sar]
<Options>: A: saf (homo sapiens) (aka fas antisense rna 1)
B: safa (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
C: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
D: saf-b (homo sapiens) (aka scaffold attachment factor b)
E: saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
F: sarp (homo sapiens) (aka ankyrin repeat domain 42)
G: saraf (homo sapiens) (aka store-operated calcium entry associated regulatory factor)
H: sara1 (homo sapiens) (aka secretion associated ras related gtpase 1a)
I: sra (drosophila melanogaster) (sarah (drosophila melanogaster)) (aka sarah)
J: sar1 (arabidopsis thaliana) (suppressor of auxin resistance1 (arabidopsis thaliana)) (aka suppressor of auxin resistance1)
K: None of the above. | [B; K] |
<Instruct>: Given the context 'Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [udp-glcnac:gal beta 1-3-galnac-r (glcnac to galnac) beta 1-6glcnac transferase]
<Options>: A: provisional ortholog of core 1 synthase, glycoprotein-n-acetylgalactosamine 3-beta-galactosyltransferase 1 (xenopus tropicalis) (aka provisional ortholog of core 1 synthase, glycoprotein-n-acetylgalactosamine 3-beta-galactosyltransferase 1)
B: galnact (homo sapiens) (aka beta-1,4-n-acetyl-galactosaminyltransferase 1)
C: galnact16 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 16)
D: galnt1 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 1)
E: c2glcnact (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 1)
F: None of the above. | [E] |
<Instruct>: Given the context 'A cDNA encoding UDP-GlcNAc:Gal beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase (EC 2.4.1.102), which forms critical branches in O-glycans, has been isolated by an expression cloning approach using Chinese hamster ovary (CHO) cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [udp-glcnac:gal beta 1-3galnac-r (glcnac to galnac) beta 1-6glcnac transferase]
<Options>: A: galnact (homo sapiens) (aka beta-1,4-n-acetyl-galactosaminyltransferase 1)
B: galnt6 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 6)
C: galnt1 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 1)
D: c2gnt (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 1)
E: galnt2 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 2)
F: None of the above. | [D] |
<Instruct>: Given the context 'Because the antibody used was found to detect most efficiently the oligosaccharide products attached to leukosialin, the CHO cells were also stably transfected with leukosialin cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [leukosialin]
<Options>: A: spn (xenopus tropicalis) (sialophorin (xenopus tropicalis)) (aka sialophorin)
B: sialophorin (homo sapiens) (aka sialophorin)
C: sialophorin (sus scrofa) (aka sialophorin)
D: galn (homo sapiens) (aka galanin and gmap prepropeptide)
E: leukosialin-like (rattus norvegicus) (aka leukosialin-like)
F: None of the above. | [B] |
<Instruct>: Given the context 'The expression of the presumed catalytic domain as a fusion protein with the IgG binding domain of protein A enabled us to demonstrate unequivocally that the cDNA encodes the core 2 beta-1,6-N-acetylglucosaminyltransferase, the enzyme responsible for the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [core 2 beta-1,6-n-acetylglucosaminyltransferase]
<Options>: A: glucosaminyl (n-acetyl) transferase 1, core 2 (mus musculus) (aka glucosaminyl (n-acetyl) transferase 1, core 2)
B: c2gnt (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 1)
C: b3gnt1, beta-1,3-n-acetylgucosaminyltransferase 1, homolog;glyco_trans_2-like domain-containing protein (caenorhabditis elegans) (aka b3gnt1, beta-1,3-n-acetylgucosaminyltransferase 1, homolog;glyco_trans_2-like domain-containing protein)
D: c2gnt2 (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 3, mucin type)
E: core-2/i-branching beta-1,6-n-acetylglucosaminyltransferase family protein (caenorhabditis elegans) (aka core-2/i-branching beta-1,6-n-acetylglucosaminyltransferase family protein)
F: None of the above. | [B] |
<Instruct>: Given the context 'Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.
TNF is a proinflammatory cytokine that has pleiotropic effects on cells and tissues, mediated in large part by alterations in target tissue gene expression.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tumor necrosis factor-alpha; tnf]
<Options>: A: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
B: tnfa (homo sapiens) (aka tumor necrosis factor)
C: tnfb (homo sapiens) (aka lymphotoxin alpha)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tnfc (homo sapiens) (aka lymphotoxin beta)
F: tumor necrosis factor (xenopus tropicalis) (aka tumor necrosis factor)
G: None of the above. | [B; B] |
<Instruct>: Given the context 'Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.
TNF is a proinflammatory cytokine that has pleiotropic effects on cells and tissues, mediated in large part by alterations in target tissue gene expression.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tumor necrosis factor-alpha; tnf]
<Options>: A: tnfc (homo sapiens) (aka lymphotoxin beta)
B: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
C: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
D: tnf (homo sapiens) (aka tumor necrosis factor)
E: tumor necrosis factor (xenopus tropicalis) (aka tumor necrosis factor)
F: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
G: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
H: None of the above. | [D; D] |
<Instruct>: Given the context 'We have used the technique of differential hybridization to identify several primary response genes induced by TNF in human umbilical vein endothelial (HUVE) cells, a cell type that is profoundly activated by cytokine treatment.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tnf]
<Options>: A: tnf (homo sapiens) (aka tumor necrosis factor)
B: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
C: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
F: None of the above. | [A] |
<Instruct>: Given the context 'One of these cDNA, designated B94, detects a rapidly and transiently induced 4-kb transcript in TNF-treated HUVE cells, and this transcript is superinduced in the concomitant presence of cycloheximide.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94; tnf]
<Options>: A: tnfc (homo sapiens) (aka lymphotoxin beta)
B: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
C: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
D: tnf (homo sapiens) (aka tumor necrosis factor)
E: rp94 (homo sapiens) (aka spermatogenesis associated 7)
F: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
G: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
H: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
I: cp94 (homo sapiens) (aka beaded filament structural protein 1)
J: b94 (homo sapiens) (aka tnf alpha induced protein 2)
K: None of the above. | [J; D] |
<Instruct>: Given the context 'One of these cDNA, designated B94, detects a rapidly and transiently induced 4-kb transcript in TNF-treated HUVE cells, and this transcript is superinduced in the concomitant presence of cycloheximide.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94; tnf]
<Options>: A: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
B: b94 (homo sapiens) (aka tnf alpha induced protein 2)
C: cp94 (homo sapiens) (aka beaded filament structural protein 1)
D: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
E: p94 (homo sapiens) (aka calpain 3)
F: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
G: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
H: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
I: tnf (homo sapiens) (aka tumor necrosis factor)
J: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
K: None of the above. | [B; I] |
<Instruct>: Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-1 beta; b94]
<Options>: A: ifnb (homo sapiens) (aka interferon beta 1)
B: interleukin 36 beta (homo sapiens) (aka interleukin 36 beta)
C: il1beta (homo sapiens) (aka interleukin 1 beta)
D: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
E: b94 (homo sapiens) (aka tnf alpha induced protein 2)
F: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
G: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
H: rp94 (homo sapiens) (aka spermatogenesis associated 7)
I: None of the above. | [C; E] |
<Instruct>: Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-1 beta; b94]
<Options>: A: ifnb (homo sapiens) (aka interferon beta 1)
B: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
C: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
D: b94 (homo sapiens) (aka tnf alpha induced protein 2)
E: interleukin 36 beta (homo sapiens) (aka interleukin 36 beta)
F: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
G: il1beta (homo sapiens) (aka interleukin 1 beta)
H: rp94 (homo sapiens) (aka spermatogenesis associated 7)
I: None of the above. | [G; D] |
<Instruct>: Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-1 beta; b94]
<Options>: A: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
B: ifnb (homo sapiens) (aka interferon beta 1)
C: interleukin 36 beta (homo sapiens) (aka interleukin 36 beta)
D: b94 (homo sapiens) (aka tnf alpha induced protein 2)
E: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
F: rp94 (homo sapiens) (aka spermatogenesis associated 7)
G: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
H: None of the above. | [H; D] |
<Instruct>: Given the context 'Nuclear run-on experiments demonstrate that TNF induction of B94 transcript occurs primarily at the level of transcriptional activation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tnf; b94]
<Options>: A: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
B: tnfc (homo sapiens) (aka lymphotoxin beta)
C: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: b94 (homo sapiens) (aka tnf alpha induced protein 2)
F: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
G: tnf (homo sapiens) (aka tumor necrosis factor)
H: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
I: p94 (homo sapiens) (aka calpain 3)
J: cp94 (homo sapiens) (aka beaded filament structural protein 1)
K: None of the above. | [G; E] |
<Instruct>: Given the context 'Nuclear run-on experiments demonstrate that TNF induction of B94 transcript occurs primarily at the level of transcriptional activation.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tnf; b94]
<Options>: A: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
B: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
C: b94 (homo sapiens) (aka tnf alpha induced protein 2)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
F: p94 (homo sapiens) (aka calpain 3)
G: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
H: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
I: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
J: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
K: None of the above. | [B; C] |
<Instruct>: Given the context 'Further, B94 is shown to be a single copy gene that is evolutionarily conserved.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94]
<Options>: A: cp94 (homo sapiens) (aka beaded filament structural protein 1)
B: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
C: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
D: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
E: b94 (homo sapiens) (aka tnf alpha induced protein 2)
F: None of the above. | [E] |
<Instruct>: Given the context 'Developmental regulation occurs most prominently in mouse embryonic liver and kidney, and a second smaller form of B94 transcript is detected in the placenta and testes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94]
<Options>: A: p94 (homo sapiens) (aka calpain 3)
B: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
C: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
D: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
E: b94 (homo sapiens) (aka tnf alpha induced protein 2)
F: None of the above. | [E] |
<Instruct>: Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94; tnf]
<Options>: A: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
B: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
C: b94 (homo sapiens) (aka tnf alpha induced protein 2)
D: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
E: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
F: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
G: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
H: tnfc (homo sapiens) (aka lymphotoxin beta)
I: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
J: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
K: None of the above. | [C; I] |
<Instruct>: Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94; tnf]
<Options>: A: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
B: tnfc (homo sapiens) (aka lymphotoxin beta)
C: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
D: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
E: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
F: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
G: p94 (homo sapiens) (aka calpain 3)
H: b94 (homo sapiens) (aka tnf alpha induced protein 2)
I: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
J: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
K: None of the above. | [H; C] |
<Instruct>: Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94; tnf]
<Options>: A: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
B: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
C: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
F: p94 (homo sapiens) (aka calpain 3)
G: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
H: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
I: tnfc (homo sapiens) (aka lymphotoxin beta)
J: None of the above. | [J; B] |
<Instruct>: Given the context 'Sequence analysis of the B94 cDNA reveals an open reading frame encoding a 73-kDa polypeptide that has no homology to any known protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94]
<Options>: A: cp94 (homo sapiens) (aka beaded filament structural protein 1)
B: b94 (homo sapiens) (aka tnf alpha induced protein 2)
C: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
D: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
E: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
F: None of the above. | [B] |
<Instruct>: Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94; tnf]
<Options>: A: tnfb (homo sapiens) (aka lymphotoxin alpha)
B: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
C: b94 (homo sapiens) (aka tnf alpha induced protein 2)
D: rp94 (homo sapiens) (aka spermatogenesis associated 7)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
G: cp94 (homo sapiens) (aka beaded filament structural protein 1)
H: tnfa (homo sapiens) (aka tumor necrosis factor)
I: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
J: tnfc (homo sapiens) (aka lymphotoxin beta)
K: None of the above. | [C; H] |
<Instruct>: Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [b94; tnf]
<Options>: A: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
B: b94 (homo sapiens) (aka tnf alpha induced protein 2)
C: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
D: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
G: p94 (homo sapiens) (aka calpain 3)
H: tnf (homo sapiens) (aka tumor necrosis factor)
I: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
J: cp94 (homo sapiens) (aka beaded filament structural protein 1)
K: None of the above. | [B; H] |
<Instruct>: Given the context 'A approximately 35-kDa polypeptide with a unique NH2-terminal sequence has been isolated from bovine lung and found to be present on the surface of endothelial cells where it mediates the binding of AGEs (receptor for advanced glycosylation end product or RAGE).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage]
<Options>: A: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
B: rage1 (homo sapiens) (aka mok protein kinase)
C: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
D: en-rage (bos taurus) (aka s100 calcium binding protein a12)
E: rage (xenopus laevis) (aka mok protein kinase l homeolog)
F: None of the above. | [A] |
<Instruct>: Given the context 'Using an oligonucleotide probe based on the amino-terminal sequence of RAGE, an apparently full-length cDNA of 1.5 kilobases was isolated from a bovine lung cDNA library.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage]
<Options>: A: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
B: rage-1 (xenopus tropicalis) (aka mok protein kinase)
C: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
D: rage1 (homo sapiens) (aka mok protein kinase)
E: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
F: None of the above. | [A] |
<Instruct>: Given the context 'A partial clone encoding the human counterpart of RAGE, isolated from a human lung library, was found to be approximately 90% homologous to the bovine molecule.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage]
<Options>: A: rage-1 (homo sapiens) (aka mok protein kinase)
B: en-rage (bos taurus) (aka s100 calcium binding protein a12)
C: rage (xenopus laevis) (aka mok protein kinase l homeolog)
D: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
E: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
F: None of the above. | [E] |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage; muc 18; ncam]
<Options>: A: ncam1 (homo sapiens) (aka neural cell adhesion molecule 1)
B: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
C: muc18 (homo sapiens) (aka melanoma cell adhesion molecule)
D: rage (gallus gallus) (aka mok protein kinase)
E: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
F: k18 (homo sapiens) (aka keratin 18)
G: ncam-1 (mus musculus) (aka neural cell adhesion molecule 1)
H: ncam-l1 (mus musculus) (aka l1 cell adhesion molecule)
I: muc-15 (homo sapiens) (aka mucin 15, cell surface associated)
J: ceacam18 (homo sapiens) (aka cea cell adhesion molecule 18)
K: ncam (neural cell adhesion molecule) homolog (caenorhabditis elegans) (aka ncam (neural cell adhesion molecule) homolog)
L: major urinary protein 18 (mus musculus) (aka major urinary protein 18)
M: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
N: ncam-l1 (homo sapiens) (aka l1 cell adhesion molecule)
O: rage1 (homo sapiens) (aka mok protein kinase)
P: None of the above. | [M; C; A] |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage; muc 18; ncam]
<Options>: A: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
B: muc18 (homo sapiens) (aka melanoma cell adhesion molecule)
C: mucin-18 (gallus gallus) (aka melanoma cell adhesion molecule)
D: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
E: en-rage (bos taurus) (aka s100 calcium binding protein a12)
F: ncam1 (homo sapiens) (aka neural cell adhesion molecule 1)
G: ceacam1 (homo sapiens) (aka cea cell adhesion molecule 1)
H: ncam-l1 (homo sapiens) (aka l1 cell adhesion molecule)
I: ncam (mus musculus) (aka neural cell adhesion molecule 1)
J: rage1 (homo sapiens) (aka mok protein kinase)
K: ncam-c (rattus norvegicus) (aka neural cell adhesion molecule 1)
L: major urinary protein 18 (mus musculus) (aka major urinary protein 18)
M: muc8 (homo sapiens) (aka mucin 8)
N: cea cell adhesion molecule 18 (homo sapiens) (aka cea cell adhesion molecule 18)
O: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
P: None of the above. | [A; B; F] |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage; muc 18; ncam]
<Options>: A: muc18 (homo sapiens) (aka melanoma cell adhesion molecule)
B: ncam (homo sapiens) (aka neural cell adhesion molecule 1)
C: ncam-l1 (homo sapiens) (aka l1 cell adhesion molecule)
D: ck-18 (homo sapiens) (aka keratin 18)
E: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
F: ncam-1 (mus musculus) (aka neural cell adhesion molecule 1)
G: muc-15 (homo sapiens) (aka mucin 15, cell surface associated)
H: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
I: ncam-c (rattus norvegicus) (aka neural cell adhesion molecule 1)
J: rage (xenopus laevis) (aka mok protein kinase l homeolog)
K: rage-1 (xenopus tropicalis) (aka mok protein kinase)
L: muc8 (homo sapiens) (aka mucin 8)
M: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
N: ceacam1 (homo sapiens) (aka cea cell adhesion molecule 1)
O: muc16 (homo sapiens) (aka mucin 16, cell surface associated)
P: None of the above. | [E; A; B] |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd20]
<Options>: A: cd20 (rattus norvegicus) (aka membrane spanning 4-domains a1)
B: cd20 (homo sapiens) (membrane spanning 4-domains a1 (homo sapiens)) (aka membrane spanning 4-domains a1)
C: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
D: cd20l (homo sapiens) (aka membrane spanning 4-domains a3)
E: cd208 (homo sapiens) (aka lysosomal associated membrane protein 3)
F: None of the above. | [B] |
<Instruct>: Given the context 'Expression of the RAGE cDNA in 293 cells allowed them to bind 125I-AGE-albumin in a saturable and dose-dependent manner (Kd approximately 100 nM), blocked by antibody to RAGE.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage]
<Options>: A: rage-1 (xenopus tropicalis) (aka mok protein kinase)
B: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
D: en-rage (bos taurus) (aka s100 calcium binding protein a12)
E: rage1 (homo sapiens) (aka mok protein kinase)
F: None of the above. | [C] |
<Instruct>: Given the context 'Western blots of 293 cells transfected with RAGE cDNA probed with anti-RAGE IgG demonstrated expression of immunoreactive protein compared to its absence in mock-transfected cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage]
<Options>: A: rage1 (homo sapiens) (aka mok protein kinase)
B: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
C: rage (gallus gallus) (aka mok protein kinase)
D: en-rage (bos taurus) (aka s100 calcium binding protein a12)
E: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
F: None of the above. | [B] |
<Instruct>: Given the context 'Western blots of 293 cells transfected with RAGE cDNA probed with anti-RAGE IgG demonstrated expression of immunoreactive protein compared to its absence in mock-transfected cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage]
<Options>: A: rage (gallus gallus) (aka mok protein kinase)
B: rage1 (homo sapiens) (aka mok protein kinase)
C: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
D: en-rage (bos taurus) (aka s100 calcium binding protein a12)
E: None of the above. | [E] |
<Instruct>: Given the context 'These results suggest that RAGE functions as a cell surface receptor for AGEs, which could potentially mediate cellular effects of this class of glycosylated proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rage]
<Options>: A: en-rage (bos taurus) (aka s100 calcium binding protein a12)
B: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
C: rage (gallus gallus) (aka mok protein kinase)
D: rage-1 (xenopus tropicalis) (aka mok protein kinase)
E: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
F: None of the above. | [B] |
<Instruct>: Given the context 'Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; ly-6]
<Options>: A: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
B: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
C: cd51 (homo sapiens) (aka integrin subunit alpha v)
D: ly5 (homo sapiens) (aka protein tyrosine phosphatase receptor type c)
E: ly-6d (homo sapiens) (aka lymphocyte antigen 6 family member d)
F: cd6 molecule (homo sapiens) (aka cd6 molecule)
G: lymphocyte antigen 6 family member h (homo sapiens) (aka lymphocyte antigen 6 family member h)
H: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
I: cd58 (homo sapiens) (aka cd58 molecule)
J: slam family member 6 (homo sapiens) (aka slam family member 6)
K: None of the above. | [H; K] |
<Instruct>: Given the context 'Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; ly-6]
<Options>: A: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
B: lymphocyte antigen 6 family member s (homo sapiens) (aka lymphocyte antigen 6 family member s)
C: slam family member 6 (homo sapiens) (aka slam family member 6)
D: ly-6d (homo sapiens) (aka lymphocyte antigen 6 family member d)
E: cd5 (homo sapiens) (aka cd5 molecule)
F: cd58 (homo sapiens) (aka cd58 molecule)
G: cd59 molecule (cd59 blood group) (homo sapiens) (aka cd59 molecule (cd59 blood group))
H: cd6 molecule (homo sapiens) (aka cd6 molecule)
I: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
J: lir-6 (homo sapiens) (aka leukocyte immunoglobulin like receptor a1)
K: None of the above. | [G; K] |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; membrane inhibitor of reactive lysis; mirl; protectin]
<Options>: A: pleiotrophin promoter (homo sapiens) (aka pleiotrophin promoter)
B: mire (homo sapiens) (aka sap30 divergent transcript)
C: cd51 (homo sapiens) (aka integrin subunit alpha v)
D: cd58 (homo sapiens) (aka cd58 molecule)
E: mir (drosophila melanogaster) (miranda (drosophila melanogaster)) (aka miranda)
F: placentin (homo sapiens) (aka insulin like 4)
G: miro (drosophila melanogaster) (mitochondrial rho (drosophila melanogaster)) (aka mitochondrial rho)
H: cd52 (homo sapiens) (aka cd52 molecule)
I: cd5 (homo sapiens) (aka cd5 molecule)
J: mical-like (drosophila melanogaster) (aka mical-like)
K: migration and invasion inhibitory protein (bos taurus) (aka migration and invasion inhibitory protein)
L: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
M: sod (homo sapiens) (aka superoxide dismutase 1)
N: proprotein convertase subtilisin/kexin type 1 inhibitor (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
O: intercellular adhesion molecule 1-like (bos taurus) (aka intercellular adhesion molecule 1-like)
P: recoverin (homo sapiens) (aka recoverin)
Q: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
R: bmp and activin membrane bound inhibitor (homo sapiens) (aka bmp and activin membrane bound inhibitor)
S: None of the above. | [L; L; L; L] |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; membrane inhibitor of reactive lysis; mirl; protectin]
<Options>: A: mire (homo sapiens) (aka sap30 divergent transcript)
B: intercellular adhesion molecule 1-like (bos taurus) (aka intercellular adhesion molecule 1-like)
C: proprotein convertase subtilisin/kexin type 1 inhibitor (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
D: pleiotrophin promoter (homo sapiens) (aka pleiotrophin promoter)
E: mir (mus musculus) (myosin regulatory light chain interacting protein (mus musculus)) (aka myosin regulatory light chain interacting protein)
F: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
G: mir (homo sapiens) (myosin regulatory light chain interacting protein (homo sapiens)) (aka myosin regulatory light chain interacting protein)
H: miro (drosophila melanogaster) (mitochondrial rho (drosophila melanogaster)) (aka mitochondrial rho)
I: metalloproteinase inhibitor 1-like (bos taurus) (aka metalloproteinase inhibitor 1-like)
J: cd51 (homo sapiens) (aka integrin subunit alpha v)
K: placentin (homo sapiens) (aka insulin like 4)
L: cd5 (homo sapiens) (aka cd5 molecule)
M: cd59 molecule (cd59 blood group) (homo sapiens) (aka cd59 molecule (cd59 blood group))
N: sod (homo sapiens) (aka superoxide dismutase 1)
O: cd52 (homo sapiens) (aka cd52 molecule)
P: migration and invasion inhibitory protein (homo sapiens) (aka migration and invasion inhibitory protein)
Q: recoverin (homo sapiens) (aka recoverin)
R: cd58 (homo sapiens) (aka cd58 molecule)
S: None of the above. | [M; M; M; M] |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; membrane inhibitor of reactive lysis; mirl; protectin]
<Options>: A: sod (homo sapiens) (aka superoxide dismutase 1)
B: migration and invasion inhibitory protein (homo sapiens) (aka migration and invasion inhibitory protein)
C: proprotein convertase subtilisin/kexin type 1 inhibitor (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
D: cd52 (homo sapiens) (aka cd52 molecule)
E: migration and invasion inhibitory protein (bos taurus) (aka migration and invasion inhibitory protein)
F: minute-like (drosophila melanogaster) (aka minute-like)
G: cd58 molecule (homo sapiens) (aka cd58 molecule)
H: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
I: cd58 (homo sapiens) (aka cd58 molecule)
J: ribonuclease/angiogenin inhibitor 1 (mus musculus) (aka ribonuclease/angiogenin inhibitor 1)
K: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
L: mire (homo sapiens) (aka sap30 divergent transcript)
M: copper chaperone for superoxide dismutase (homo sapiens) (aka copper chaperone for superoxide dismutase)
N: recoverin (homo sapiens) (aka recoverin)
O: fallotein (homo sapiens) (aka platelet derived growth factor c)
P: miro (drosophila melanogaster) (mitochondrial rho (drosophila melanogaster)) (aka mitochondrial rho)
Q: cd51 (homo sapiens) (aka integrin subunit alpha v)
R: mir (mus musculus) (myosin regulatory light chain interacting protein (mus musculus)) (aka myosin regulatory light chain interacting protein)
S: None of the above. | [K; K; K; K] |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; membrane inhibitor of reactive lysis; mirl; protectin]
<Options>: A: cd58 (homo sapiens) (aka cd58 molecule)
B: mical-like (drosophila melanogaster) (aka mical-like)
C: proprotein convertase subtilisin/kexin type 1 inhibitor (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
D: pleiotrophin promoter (homo sapiens) (aka pleiotrophin promoter)
E: cd59 molecule (cd59 blood group) (homo sapiens) (aka cd59 molecule (cd59 blood group))
F: mir (mus musculus) (myosin regulatory light chain interacting protein (mus musculus)) (aka myosin regulatory light chain interacting protein)
G: fallotein (homo sapiens) (aka platelet derived growth factor c)
H: cd51 (homo sapiens) (aka integrin subunit alpha v)
I: migration and invasion inhibitory protein (bos taurus) (aka migration and invasion inhibitory protein)
J: cd52 (homo sapiens) (aka cd52 molecule)
K: sod (homo sapiens) (aka superoxide dismutase 1)
L: recoverin (homo sapiens) (aka recoverin)
M: miro (drosophila melanogaster) (mitochondrial rho (drosophila melanogaster)) (aka mitochondrial rho)
N: bmp and activin membrane bound inhibitor (homo sapiens) (aka bmp and activin membrane bound inhibitor)
O: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
P: ribonuclease/angiogenin inhibitor 1 (mus musculus) (aka ribonuclease/angiogenin inhibitor 1)
Q: minute-like (drosophila melanogaster) (aka minute-like)
R: None of the above. | [E; E; E; E] |
<Instruct>: Given the context 'The structure of the CD59 gene is very similar to that encoding Ly-6, a murine glycoprotein with which CD59 has some structural similarity.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; ly-6]
<Options>: A: ly5 (homo sapiens) (aka protein tyrosine phosphatase receptor type c)
B: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
C: cd58 (homo sapiens) (aka cd58 molecule)
D: cd6 molecule (homo sapiens) (aka cd6 molecule)
E: ly-6d (homo sapiens) (aka lymphocyte antigen 6 family member d)
F: cd51 (homo sapiens) (aka integrin subunit alpha v)
G: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
H: slam family member 7 (homo sapiens) (aka slam family member 7)
I: lymphocyte antigen 6 family member h (homo sapiens) (aka lymphocyte antigen 6 family member h)
J: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
K: None of the above. | [G; K] |
<Instruct>: Given the context 'The structure of the CD59 gene is very similar to that encoding Ly-6, a murine glycoprotein with which CD59 has some structural similarity.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd59; ly-6]
<Options>: A: cd58 (homo sapiens) (aka cd58 molecule)
B: lymphocyte antigen 6 family member h (homo sapiens) (aka lymphocyte antigen 6 family member h)
C: slam family member 7 (homo sapiens) (aka slam family member 7)
D: cd6 molecule (homo sapiens) (aka cd6 molecule)
E: ly5 (homo sapiens) (aka protein tyrosine phosphatase receptor type c)
F: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
G: cd52 molecule (homo sapiens) (aka cd52 molecule)
H: ly-6d (homo sapiens) (aka lymphocyte antigen 6 family member d)
I: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
J: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
K: None of the above. | [I; K] |
<Instruct>: Given the context 'The striking similarity in gene structure is further evidence that the two proteins belong to a superfamily of proteins that may also include the urokinase plasminogen-activator receptor and a squid glycoprotein of unknown function.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [urokinase plasminogen-activator receptor]
<Options>: A: urokinase plasminogen activator surface receptor-like (danio rerio) (aka urokinase plasminogen activator surface receptor-like)
B: plasminogen activator, urokinase receptor (rattus norvegicus) (aka plasminogen activator, urokinase receptor)
C: plasminogen activator, urokinase receptor (mus musculus) (aka plasminogen activator, urokinase receptor)
D: plasminogen activator, urokinase receptor (bos taurus) (aka plasminogen activator, urokinase receptor)
E: plasminogen activator, urokinase receptor (homo sapiens) (aka plasminogen activator, urokinase receptor)
F: None of the above. | [E] |
<Instruct>: Given the context 'Cloning and chromosome mapping of the human interleukin-1 receptor antagonist gene.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [interleukin-1 receptor antagonist]
<Options>: A: il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens)) (aka interleukin 1 receptor antagonist)
B: interleukin 1 receptor antagonist (rattus norvegicus) (aka interleukin 1 receptor antagonist)
C: il1rp1 (homo sapiens) (aka interleukin 37)
D: interleukin 1 receptor antagonist (mus musculus) (aka interleukin 1 receptor antagonist)
E: il11ra (homo sapiens) (aka interleukin 11 receptor subunit alpha)
F: None of the above. | [A] |
<Instruct>: Given the context 'By screening a human genomic library with an interleukin-1 receptor antagonist (IL-1ra) cDNA probe, we have isolated a 15 kb clone which contains the entire coding region of the gene as expressed in monocytes, and includes 6 kb of 5'-upstream sequence.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [interleukin-1 receptor antagonist; il-1ra]
<Options>: A: il-1ra (homo sapiens) (interleukin 6 receptor (homo sapiens)) (aka interleukin 6 receptor)
B: il-1rrp (homo sapiens) (aka interleukin 18 receptor 1)
C: interleukin 1 receptor antagonist (rattus norvegicus) (aka interleukin 1 receptor antagonist)
D: il-1r-alpha (homo sapiens) (aka interleukin 1 receptor type 1)
E: il1rn (homo sapiens) (aka interleukin 1 receptor antagonist)
F: interleukin 36 receptor antagonist (homo sapiens) (aka interleukin 36 receptor antagonist)
G: il1rp1 (homo sapiens) (aka interleukin 37)
H: il-1racp (homo sapiens) (aka interleukin 1 receptor accessory protein)
I: interleukin 1 receptor antagonist (mus musculus) (aka interleukin 1 receptor antagonist)
J: None of the above. | [E; E] |
<Instruct>: Given the context 'By screening a human genomic library with an interleukin-1 receptor antagonist (IL-1ra) cDNA probe, we have isolated a 15 kb clone which contains the entire coding region of the gene as expressed in monocytes, and includes 6 kb of 5'-upstream sequence.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [interleukin-1 receptor antagonist; il-1ra]
<Options>: A: il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens)) (aka interleukin 1 receptor antagonist)
B: il-1ra (homo sapiens) (interleukin 6 receptor (homo sapiens)) (aka interleukin 6 receptor)
C: il1rp1 (homo sapiens) (aka interleukin 37)
D: il-1rrp (homo sapiens) (aka interleukin 18 receptor 1)
E: il11ra (homo sapiens) (aka interleukin 11 receptor subunit alpha)
F: interleukin 1 receptor antagonist (mus musculus) (aka interleukin 1 receptor antagonist)
G: il1rap (homo sapiens) (aka interleukin 1 receptor accessory protein)
H: interleukin 1 receptor antagonist (rattus norvegicus) (aka interleukin 1 receptor antagonist)
I: None of the above. | [A; A] |
<Instruct>: Given the context 'The gene contains four exons which code for the secreted form of the IL-1ra, however, our clone does not contain the alternative first exon used to generate an intracellular form of the protein as the protein as found in epithelial cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-1ra]
<Options>: A: il-1racp (homo sapiens) (aka interleukin 1 receptor accessory protein)
B: il-1rrp (homo sapiens) (aka interleukin 18 receptor 1)
C: il-1r-alpha (homo sapiens) (aka interleukin 1 receptor type 1)
D: icil-1ra (homo sapiens) (aka interleukin 1 receptor antagonist)
E: il-1ra (homo sapiens) (interleukin 6 receptor (homo sapiens)) (aka interleukin 6 receptor)
F: None of the above. | [D] |
<Instruct>: Given the context 'By in-situ fluorescence hybridization we have shown that the IL-1ra gene is found on the long arm of chromosome 2 and maps to 2q13-14.1.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-1ra]
<Options>: A: il-1r-alpha (homo sapiens) (aka interleukin 1 receptor type 1)
B: il-1rrp (homo sapiens) (aka interleukin 18 receptor 1)
C: il1rap (homo sapiens) (aka interleukin 1 receptor accessory protein)
D: il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens)) (aka interleukin 1 receptor antagonist)
E: il-1ra (homo sapiens) (interleukin 6 receptor (homo sapiens)) (aka interleukin 6 receptor)
F: None of the above. | [D] |
<Instruct>: Given the context 'Previous studies have revealed that IL-1 alpha, and IL-1 beta and both type I and type II forms of the IL-1 receptor all map close to this region of chromosome 2.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-1 alpha; il-1 beta]
<Options>: A: il1b (homo sapiens) (aka interleukin 1 beta)
B: il-1h1 (homo sapiens) (aka interleukin 36 gamma)
C: ifn-beta (homo sapiens) (aka interferon beta 1)
D: il-1 (homo sapiens) (aka interleukin 1 beta)
E: interferon alpha 1 (homo sapiens) (aka interferon alpha 1)
F: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
G: interleukin 36 beta (homo sapiens) (aka interleukin 36 beta)
H: interleukin 1 alpha (homo sapiens) (aka interleukin 1 alpha)
I: None of the above. | [H; A] |
<Instruct>: Given the context 'Previous studies have revealed that IL-1 alpha, and IL-1 beta and both type I and type II forms of the IL-1 receptor all map close to this region of chromosome 2.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [il-1 alpha; il-1 beta]
<Options>: A: il-1h1 (homo sapiens) (aka interleukin 36 gamma)
B: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
C: il1a (homo sapiens) (aka interleukin 1 alpha)
D: interleukin 36 beta (homo sapiens) (aka interleukin 36 beta)
E: interleukin 1 beta (homo sapiens) (aka interleukin 1 beta)
F: il-1 (homo sapiens) (aka interleukin 1 beta)
G: interferon alpha 1 (homo sapiens) (aka interferon alpha 1)
H: ifnb1 (homo sapiens) (aka interferon beta 1)
I: None of the above. | [C; E] |
<Instruct>: Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; eaoh; early-onset ataxia with ocular motor apraxia and hypoalbuminemia]
<Options>: A: episodic ataxia, type 7 (homo sapiens) (aka episodic ataxia, type 7)
B: eay (drosophila melanogaster) (early (drosophila melanogaster)) (aka early)
C: aprataxin (sus scrofa) (aka aprataxin)
D: aoeb166 (homo sapiens) (aka peroxiredoxin 5)
E: aprataxin (xenopus tropicalis) (aka aprataxin)
F: aprataxin (homo sapiens) (aka aprataxin)
G: episodic ataxia, type 3 (homo sapiens) (aka episodic ataxia, type 3)
H: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
I: cogan-type congential oculomotor apraxia (homo sapiens) (aka cogan-type congential oculomotor apraxia)
J: oohe (homo sapiens) (aka unc-45 myosin chaperone a)
K: eay (drosophila melanogaster) (eyes absent (drosophila melanogaster)) (aka eyes absent)
L: hae (arabidopsis thaliana) (aka leucine-rich receptor-like protein kinase family protein)
M: aprataxin l homeolog (xenopus laevis) (aka aprataxin l homeolog)
N: None of the above. | [F; F; F] |
<Instruct>: Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; eaoh; early-onset ataxia with ocular motor apraxia and hypoalbuminemia]
<Options>: A: oohe (homo sapiens) (aka unc-45 myosin chaperone a)
B: episodic ataxia, type 3 (homo sapiens) (aka episodic ataxia, type 3)
C: aprataxin (sus scrofa) (aka aprataxin)
D: episodic ataxia, type 7 (homo sapiens) (aka episodic ataxia, type 7)
E: aoeb166 (homo sapiens) (aka peroxiredoxin 5)
F: hae (arabidopsis thaliana) (aka leucine-rich receptor-like protein kinase family protein)
G: eay (drosophila melanogaster) (eyes absent (drosophila melanogaster)) (aka eyes absent)
H: cogan-type congential oculomotor apraxia (homo sapiens) (aka cogan-type congential oculomotor apraxia)
I: aprataxin l homeolog (xenopus laevis) (aka aprataxin l homeolog)
J: aprataxin (xenopus tropicalis) (aka aprataxin)
K: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
L: eay (drosophila melanogaster) (early (drosophila melanogaster)) (aka early)
M: None of the above. | [M; M; M] |
<Instruct>: Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; eaoh; early-onset ataxia with ocular motor apraxia and hypoalbuminemia]
<Options>: A: yhae (escherichia coli str. k-12 substr. mg1655) (aka tartronate semialdehyde reductase)
B: aprataxin (drosophila melanogaster) (aka aprataxin)
C: episodic ataxia, type 8 (homo sapiens) (aka episodic ataxia, type 8)
D: cogan-type congential oculomotor apraxia (homo sapiens) (aka cogan-type congential oculomotor apraxia)
E: aprataxin (homo sapiens) (aka aprataxin)
F: hae (arabidopsis thaliana) (aka leucine-rich receptor-like protein kinase family protein)
G: eaa1 (homo sapiens) (aka glutamate ionotropic receptor kainate type subunit 4)
H: etaa1 (homo sapiens) (aka etaa1 activator of atr kinase)
I: episodic ataxia, type 3 (homo sapiens) (aka episodic ataxia, type 3)
J: oohe (homo sapiens) (aka unc-45 myosin chaperone a)
K: aprataxin (sus scrofa) (aka aprataxin)
L: aprataxin l homeolog (xenopus laevis) (aka aprataxin l homeolog)
M: aprataxin-like protein (arabidopsis thaliana) (aka aprataxin-like protein)
N: None of the above. | [E; E; E] |
<Instruct>: Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; eaoh; early-onset ataxia with ocular motor apraxia and hypoalbuminemia]
<Options>: A: episodic ataxia, type 7 (homo sapiens) (aka episodic ataxia, type 7)
B: aprataxin (homo sapiens) (aka aprataxin)
C: aprataxin (mus musculus) (aka aprataxin)
D: episodic ataxia, type 3 (homo sapiens) (aka episodic ataxia, type 3)
E: hae (arabidopsis thaliana) (aka leucine-rich receptor-like protein kinase family protein)
F: yhae (escherichia coli str. k-12 substr. mg1655) (aka tartronate semialdehyde reductase)
G: aprataxin (drosophila melanogaster) (aka aprataxin)
H: eaa1 (homo sapiens) (aka glutamate ionotropic receptor kainate type subunit 4)
I: aprataxin-like (xenopus laevis) (aka aprataxin-like)
J: epilepsy, occipitotemporal lobe, and migraine with aura (homo sapiens) (aka epilepsy, occipitotemporal lobe, and migraine with aura)
K: etaa1 activator of atr kinase (homo sapiens) (aka etaa1 activator of atr kinase)
L: aprataxin (xenopus tropicalis) (aka aprataxin)
M: None of the above. | [B; B; B] |
<Instruct>: Given the context 'Recently, the causative gene for EAOH, APTX, has been identified.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [eaoh; aptx]
<Options>: A: aptx (drosophila melanogaster) (aka aprataxin)
B: hae (arabidopsis thaliana) (aka leucine-rich receptor-like protein kinase family protein)
C: oohe (homo sapiens) (aka unc-45 myosin chaperone a)
D: eaa1 (homo sapiens) (aka glutamate ionotropic receptor kainate type subunit 4)
E: etaa1 activator of atr kinase (homo sapiens) (aka etaa1 activator of atr kinase)
F: aptx (mus musculus) (aka aprataxin)
G: aptl (homo sapiens) (aka fas ligand)
H: aptx (arabidopsis thaliana) (aka aprataxin-like protein)
I: eaoh (homo sapiens) (aka aprataxin)
J: None of the above. | [I; I] |
<Instruct>: Given the context 'Recently, the causative gene for EAOH, APTX, has been identified.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [eaoh; aptx]
<Options>: A: aptl (homo sapiens) (aka fas ligand)
B: hae (arabidopsis thaliana) (aka leucine-rich receptor-like protein kinase family protein)
C: aptx (xenopus tropicalis) (aka aprataxin)
D: eaoh (homo sapiens) (aka aprataxin)
E: aptx (xenopus laevis) (aka aprataxin l homeolog)
F: etaa1 (homo sapiens) (aka etaa1 activator of atr kinase)
G: eaa1 (homo sapiens) (aka glutamate ionotropic receptor kainate type subunit 4)
H: aptx (arabidopsis thaliana) (aka aprataxin-like protein)
I: eay (drosophila melanogaster) (eyes absent (drosophila melanogaster)) (aka eyes absent)
J: None of the above. | [D; D] |
<Instruct>: Given the context 'Recently, the causative gene for EAOH, APTX, has been identified.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [eaoh; aptx]
<Options>: A: hae (arabidopsis thaliana) (aka leucine-rich receptor-like protein kinase family protein)
B: aptl (homo sapiens) (aka fas ligand)
C: aptx (xenopus laevis) (aka aprataxin l homeolog)
D: etaa1 (homo sapiens) (aka etaa1 activator of atr kinase)
E: eay (drosophila melanogaster) (eyes absent (drosophila melanogaster)) (aka eyes absent)
F: eaa1 (homo sapiens) (aka glutamate ionotropic receptor kainate type subunit 4)
G: aptx (arabidopsis thaliana) (aka aprataxin-like protein)
H: aptx (xenopus tropicalis) (aka aprataxin)
I: None of the above. | [I; I] |
<Instruct>: Given the context 'Of the two splicing variants of APTX mRNA, the short and the long forms, long-form APTX mRNA was found to be the major isoform.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aptx]
<Options>: A: aptx (xenopus laevis) (aka aprataxin l homeolog)
B: aptl (homo sapiens) (aka fas ligand)
C: aptx (xenopus tropicalis) (aka aprataxin)
D: aptx (homo sapiens) (aka aprataxin)
E: apt1 (xenopus laevis) (fas cell surface death receptor s homeolog (xenopus laevis)) (aka fas cell surface death receptor s homeolog)
F: None of the above. | [D] |
<Instruct>: Given the context 'Aprataxin is mainly located in the nucleus, and, furthermore, the first nuclear localization signal located near the amino terminus of the long-form aprataxin is essential for its nuclear localization.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin]
<Options>: A: aprataxin (homo sapiens) (aka aprataxin)
B: aprataxin (mus musculus) (aka aprataxin)
C: aprataxin (drosophila melanogaster) (aka aprataxin)
D: aprataxin (xenopus tropicalis) (aka aprataxin)
E: aprataxin-like (xenopus laevis) (aka aprataxin-like)
F: None of the above. | [A] |
<Instruct>: Given the context 'We found, based on the yeast two-hybrid and coimmunoprecipitation experiments, that the long-form but not the short-form aprataxin interacts with XRCC1 (x-ray repair cross-complementing group 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; xrcc1; x-ray repair cross-complementing group 1]
<Options>: A: aprataxin (xenopus tropicalis) (aka aprataxin)
B: xrcc9 (homo sapiens) (aka fa complementation group g)
C: aprataxin (mus musculus) (aka aprataxin)
D: xrcc1 (homo sapiens) (aka x-ray repair cross complementing 1)
E: aprataxin (sus scrofa) (aka aprataxin)
F: x-ray repair cross complementing 1 (sus scrofa) (aka x-ray repair cross complementing 1)
G: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 l homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 l homeolog)
H: aprataxin (homo sapiens) (aka aprataxin)
I: xrcc1 (oryctolagus cuniculus) (aka x-ray repair cross complementing 1)
J: x-ray repair cross complementing 1 (oryctolagus cuniculus) (aka x-ray repair cross complementing 1)
K: x-ray repair cross complementing 4 (homo sapiens) (aka x-ray repair cross complementing 4)
L: xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1)
M: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
N: None of the above. | [H; D; D] |
<Instruct>: Given the context 'We found, based on the yeast two-hybrid and coimmunoprecipitation experiments, that the long-form but not the short-form aprataxin interacts with XRCC1 (x-ray repair cross-complementing group 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; xrcc1; x-ray repair cross-complementing group 1]
<Options>: A: x-ray repair cross complementing 5 (homo sapiens) (aka x-ray repair cross complementing 5)
B: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 s homeolog)
C: xrcc11 (homo sapiens) (aka brca2 dna repair associated)
D: aprataxin (mus musculus) (aka aprataxin)
E: xrcc1 (homo sapiens) (aka x-ray repair cross complementing 1)
F: xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis)) (aka regulator of chromosome condensation 1)
G: aprataxin (homo sapiens) (aka aprataxin)
H: xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1)
I: aprataxin (xenopus tropicalis) (aka aprataxin)
J: x-ray repair cross complementing 6 (homo sapiens) (aka x-ray repair cross complementing 6)
K: aprataxin-like (xenopus laevis) (aka aprataxin-like)
L: x-ray repair cross complementing 4 (homo sapiens) (aka x-ray repair cross complementing 4)
M: aprataxin (drosophila melanogaster) (aka aprataxin)
N: x-ray repair cross complementing 1 (sus scrofa) (aka x-ray repair cross complementing 1)
O: None of the above. | [G; E; E] |
<Instruct>: Given the context 'We found, based on the yeast two-hybrid and coimmunoprecipitation experiments, that the long-form but not the short-form aprataxin interacts with XRCC1 (x-ray repair cross-complementing group 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; xrcc1; x-ray repair cross-complementing group 1]
<Options>: A: aprataxin (xenopus tropicalis) (aka aprataxin)
B: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 s homeolog)
C: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 l homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 l homeolog)
D: aprataxin (homo sapiens) (aka aprataxin)
E: x-ray repair cross complementing 4 (homo sapiens) (aka x-ray repair cross complementing 4)
F: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
G: aprataxin (sus scrofa) (aka aprataxin)
H: xrcc11 (homo sapiens) (aka brca2 dna repair associated)
I: x-ray repair cross complementing 1 (sus scrofa) (aka x-ray repair cross complementing 1)
J: x-ray repair cross complementing 3 (homo sapiens) (aka x-ray repair cross complementing 3)
K: x-ray repair cross complementing 1 (homo sapiens) (aka x-ray repair cross complementing 1)
L: xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1)
M: aprataxin-like (xenopus laevis) (aka aprataxin-like)
N: xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis)) (aka regulator of chromosome condensation 1)
O: None of the above. | [D; K; K] |
<Instruct>: Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; polynucleotidekinase-3'-phosphatase; xrcc1; dna polymerase beta]
<Options>: A: polgb (homo sapiens) (aka dna polymerase gamma 2, accessory subunit)
B: dna polymerase beta (homo sapiens) (aka dna polymerase beta)
C: xrcc1 (homo sapiens) (aka x-ray repair cross complementing 1)
D: polynucleotide kinase 3'-phosphatase (bos taurus) (aka polynucleotide kinase 3'-phosphatase)
E: polynucleotide kinase 3'-phosphatase s homeolog (xenopus laevis) (aka polynucleotide kinase 3'-phosphatase s homeolog)
F: xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1)
G: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
H: polynucleotide kinase 3'-phosphatase (sus scrofa) (aka polynucleotide kinase 3'-phosphatase)
I: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 s homeolog)
J: polynucleotide kinase 3'-phosphatase (drosophila melanogaster) (aka polynucleotide kinase 3'-phosphatase)
K: aprataxin (homo sapiens) (aka aprataxin)
L: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 l homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 l homeolog)
M: aprataxin (sus scrofa) (aka aprataxin)
N: dna polymerase iota (homo sapiens) (aka dna polymerase iota)
O: aprataxin l homeolog (xenopus laevis) (aka aprataxin l homeolog)
P: polynucleotide kinase 3'-phosphatase (homo sapiens) (aka polynucleotide kinase 3'-phosphatase)
Q: aprataxin (drosophila melanogaster) (aka aprataxin)
R: dna polymerase delta 1, catalytic subunit (homo sapiens) (aka dna polymerase delta 1, catalytic subunit)
S: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
T: xrcc11 (homo sapiens) (aka brca2 dna repair associated)
U: None of the above. | [K; P; C; B] |
<Instruct>: Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; polynucleotidekinase-3'-phosphatase; xrcc1; dna polymerase beta]
<Options>: A: xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1)
B: polynucleotide kinase 3'-phosphatase (drosophila melanogaster) (aka polynucleotide kinase 3'-phosphatase)
C: aprataxin (mus musculus) (aka aprataxin)
D: polynucleotide kinase 3'-phosphatase s homeolog (xenopus laevis) (aka polynucleotide kinase 3'-phosphatase s homeolog)
E: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
F: polynucleotide kinase 3'-phosphatase (danio rerio) (aka polynucleotide kinase 3'-phosphatase)
G: xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis)) (aka regulator of chromosome condensation 1)
H: aprataxin (homo sapiens) (aka aprataxin)
I: polynucleotide kinase 3'-phosphatase (homo sapiens) (aka polynucleotide kinase 3'-phosphatase)
J: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 s homeolog)
K: polynucleotide kinase 3'- phosphatase (mus musculus) (aka polynucleotide kinase 3'- phosphatase)
L: x-ray repair cross complementing 1 (homo sapiens) (aka x-ray repair cross complementing 1)
M: polb (homo sapiens) (dna polymerase beta (homo sapiens)) (aka dna polymerase beta)
N: aprataxin (xenopus tropicalis) (aka aprataxin)
O: dna polymerase iota (homo sapiens) (aka dna polymerase iota)
P: aprataxin l homeolog (xenopus laevis) (aka aprataxin l homeolog)
Q: aprataxin-like protein (arabidopsis thaliana) (aka aprataxin-like protein)
R: dna polymerase gamma, catalytic subunit (homo sapiens) (aka dna polymerase gamma, catalytic subunit)
S: dna polymerase delta 1, catalytic subunit (homo sapiens) (aka dna polymerase delta 1, catalytic subunit)
T: xrcc11 (homo sapiens) (aka brca2 dna repair associated)
U: None of the above. | [H; I; L; M] |
<Instruct>: Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; polynucleotidekinase-3'-phosphatase; xrcc1; dna polymerase beta]
<Options>: A: polynucleotide kinase 3'-phosphatase (homo sapiens) (aka polynucleotide kinase 3'-phosphatase)
B: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 s homeolog)
C: polg-beta (homo sapiens) (aka dna polymerase gamma 2, accessory subunit)
D: polb (homo sapiens) (dna polymerase beta (homo sapiens)) (aka dna polymerase beta)
E: xrcc11 (homo sapiens) (aka brca2 dna repair associated)
F: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
G: dna polymerase gamma, catalytic subunit (homo sapiens) (aka dna polymerase gamma, catalytic subunit)
H: aprataxin (homo sapiens) (aka aprataxin)
I: polynucleotide kinase 3'-phosphatase (drosophila melanogaster) (aka polynucleotide kinase 3'-phosphatase)
J: xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis)) (aka regulator of chromosome condensation 1)
K: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 l homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 l homeolog)
L: aprataxin (drosophila melanogaster) (aka aprataxin)
M: polynucleotide kinase 3'-phosphatase (sus scrofa) (aka polynucleotide kinase 3'-phosphatase)
N: polynucleotide kinase 3'-phosphatase (xenopus tropicalis) (aka polynucleotide kinase 3'-phosphatase)
O: aprataxin (xenopus tropicalis) (aka aprataxin)
P: dna polymerase delta 1, catalytic subunit (homo sapiens) (aka dna polymerase delta 1, catalytic subunit)
Q: polynucleotide kinase 3'- phosphatase (mus musculus) (aka polynucleotide kinase 3'- phosphatase)
R: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
S: aprataxin-like protein (arabidopsis thaliana) (aka aprataxin-like protein)
T: xrcc1 (homo sapiens) (aka x-ray repair cross complementing 1)
U: None of the above. | [H; A; T; D] |
<Instruct>: Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; polynucleotidekinase-3'-phosphatase; xrcc1; dna polymerase beta]
<Options>: A: xrcc1 (oryctolagus cuniculus) (aka x-ray repair cross complementing 1)
B: xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis)) (aka regulator of chromosome condensation 1)
C: dna polymerase iota (homo sapiens) (aka dna polymerase iota)
D: dna polymerase beta (homo sapiens) (aka dna polymerase beta)
E: aprataxin (homo sapiens) (aka aprataxin)
F: polynucleotide kinase 3'-phosphatase (drosophila melanogaster) (aka polynucleotide kinase 3'-phosphatase)
G: polynucleotide kinase 3'-phosphatase (bos taurus) (aka polynucleotide kinase 3'-phosphatase)
H: pnk (homo sapiens) (polynucleotide kinase 3'-phosphatase (homo sapiens)) (aka polynucleotide kinase 3'-phosphatase)
I: dna polymerase epsilon, catalytic subunit (homo sapiens) (aka dna polymerase epsilon, catalytic subunit)
J: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 s homeolog)
K: aprataxin-like (arabidopsis thaliana) (aka aprataxin-like protein)
L: aprataxin (drosophila melanogaster) (aka aprataxin)
M: aprataxin l homeolog (xenopus laevis) (aka aprataxin l homeolog)
N: xrcc1 (homo sapiens) (aka x-ray repair cross complementing 1)
O: polynucleotide kinase 3'- phosphatase (mus musculus) (aka polynucleotide kinase 3'- phosphatase)
P: dna polymerase delta 1, catalytic subunit (homo sapiens) (aka dna polymerase delta 1, catalytic subunit)
Q: dna polymerase gamma, catalytic subunit (homo sapiens) (aka dna polymerase gamma, catalytic subunit)
R: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
S: xrcc1 (xenopus laevis) (x-ray repair complementing defective repair in chinese hamster cells 1 l homeolog (xenopus laevis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1 l homeolog)
T: polynucleotide kinase 3'-phosphatase s homeolog (xenopus laevis) (aka polynucleotide kinase 3'-phosphatase s homeolog)
U: None of the above. | [E; H; N; D] |
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