instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [dna ligase iii]
<Options>: A: dna ligase 1 (homo sapiens) (aka dna ligase 1)
B: dna ligase 3 (oryctolagus cuniculus) (aka dna ligase 3)
C: lig3 (homo sapiens) (dna ligase 3 (homo sapiens)) (aka dna ligase 3)
D: ligase iii, dna, atp-dependent (xenopus tropicalis) (aka ligase iii, dna, atp-dependent)
E: ligase iii, dna, atp-dependent (danio rerio) (aka ligase iii, dna, atp-dependent)
F: None of the above. | [C] |
<Instruct>: Given the context 'These results strongly support the possibility that aprataxin and XRCC1 constitute a multiprotein complex and are involved in single-strand DNA break repair, and furthermore, that accumulation of unrepaired damaged DNA underlies the pathophysiological mechanisms of EAOH.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; xrcc1; eaoh]
<Options>: A: eay (drosophila melanogaster) (eyes absent (drosophila melanogaster)) (aka eyes absent)
B: xrcc1 (xenopus laevis) (x-ray repair complementing defective repair in chinese hamster cells 1 l homeolog (xenopus laevis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1 l homeolog)
C: xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis)) (aka regulator of chromosome condensation 1)
D: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
E: aprataxin l homeolog (xenopus laevis) (aka aprataxin l homeolog)
F: xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1)
G: eaa1 (homo sapiens) (aka glutamate ionotropic receptor kainate type subunit 4)
H: xrcc1 (homo sapiens) (aka x-ray repair cross complementing 1)
I: eay (drosophila melanogaster) (early (drosophila melanogaster)) (aka early)
J: aprataxin (homo sapiens) (aka aprataxin)
K: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 l homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 l homeolog)
L: aprataxin-like (xenopus laevis) (aka aprataxin-like)
M: aprataxin (drosophila melanogaster) (aka aprataxin)
N: etaa1 activator of atr kinase (homo sapiens) (aka etaa1 activator of atr kinase)
O: None of the above. | [J; H; J] |
<Instruct>: Given the context 'These results strongly support the possibility that aprataxin and XRCC1 constitute a multiprotein complex and are involved in single-strand DNA break repair, and furthermore, that accumulation of unrepaired damaged DNA underlies the pathophysiological mechanisms of EAOH.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; xrcc1; eaoh]
<Options>: A: xrcc1 (oryctolagus cuniculus) (aka x-ray repair cross complementing 1)
B: aprataxin (xenopus tropicalis) (aka aprataxin)
C: eaa1 (homo sapiens) (aka glutamate ionotropic receptor kainate type subunit 4)
D: aprataxin (mus musculus) (aka aprataxin)
E: xrcc1 (homo sapiens) (aka x-ray repair cross complementing 1)
F: xrcc11 (homo sapiens) (aka brca2 dna repair associated)
G: aprataxin (homo sapiens) (aka aprataxin)
H: etaa1 activator of atr kinase (homo sapiens) (aka etaa1 activator of atr kinase)
I: eay (drosophila melanogaster) (early (drosophila melanogaster)) (aka early)
J: eay (drosophila melanogaster) (eyes absent (drosophila melanogaster)) (aka eyes absent)
K: aprataxin (sus scrofa) (aka aprataxin)
L: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 s homeolog)
M: aprataxin-like (xenopus laevis) (aka aprataxin-like)
N: xrcc1 (xenopus laevis) (x-ray repair complementing defective repair in chinese hamster cells 1 l homeolog (xenopus laevis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1 l homeolog)
O: None of the above. | [G; E; G] |
<Instruct>: Given the context 'These results strongly support the possibility that aprataxin and XRCC1 constitute a multiprotein complex and are involved in single-strand DNA break repair, and furthermore, that accumulation of unrepaired damaged DNA underlies the pathophysiological mechanisms of EAOH.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [aprataxin; xrcc1; eaoh]
<Options>: A: x-ray repair cross complementing 1 (homo sapiens) (aka x-ray repair cross complementing 1)
B: oohe (homo sapiens) (aka unc-45 myosin chaperone a)
C: xrcc11 (homo sapiens) (aka brca2 dna repair associated)
D: aprataxin-like (xenopus laevis) (aka aprataxin-like)
E: eay (drosophila melanogaster) (eyes absent (drosophila melanogaster)) (aka eyes absent)
F: xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis)) (aka x-ray repair complementing defective repair in chinese hamster cells 1)
G: aprataxin (drosophila melanogaster) (aka aprataxin)
H: xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 l homeolog (xenopus laevis)) (aka regulator of chromosome condensation 1 l homeolog)
I: eay (drosophila melanogaster) (early (drosophila melanogaster)) (aka early)
J: aprataxin and pnkp like factor (xenopus tropicalis) (aka aprataxin and pnkp like factor)
K: xrcc9 (homo sapiens) (aka fa complementation group g)
L: aprataxin (sus scrofa) (aka aprataxin)
M: aprataxin (homo sapiens) (aka aprataxin)
N: etaa1 (homo sapiens) (aka etaa1 activator of atr kinase)
O: None of the above. | [M; A; M] |
<Instruct>: Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1; cytochrome c; caspase-9]
<Options>: A: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
B: mitochondrially encoded cytochrome c oxidase iii (homo sapiens) (aka mitochondrially encoded cytochrome c oxidase iii)
C: uqcc (homo sapiens) (aka ubiquinol-cytochrome c reductase complex assembly factor 1)
D: apa1 (homo sapiens) (aka zinc finger protein 410)
E: cytochrome c1 (homo sapiens) (aka cytochrome c1)
F: apaf-1 (xenopus tropicalis) (aka apoptotic peptidase activating factor 1)
G: caspase-9 (mus musculus) (aka caspase 9)
H: casp9 (homo sapiens) (aka caspase 9)
I: apoptotic peptidase activating factor 1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
J: apak (homo sapiens) (aka zinc finger protein 420)
K: cytochrome c, somatic (homo sapiens) (aka cytochrome c, somatic)
L: caspase 7 (homo sapiens) (aka caspase 7)
M: caspase 8 (homo sapiens) (aka caspase 8)
N: cytochrome c, somatic (oryctolagus cuniculus) (aka cytochrome c, somatic)
O: caspase-9 (xenopus tropicalis) (aka caspase 9)
P: None of the above. | [I; K; H] |
<Instruct>: Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1; cytochrome c; caspase-9]
<Options>: A: caspase-9 (mus musculus) (aka caspase 9)
B: caspase 7 (homo sapiens) (aka caspase 7)
C: cytochrome c, somatic (homo sapiens) (aka cytochrome c, somatic)
D: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
E: apak (homo sapiens) (aka zinc finger protein 420)
F: apa1 (homo sapiens) (aka zinc finger protein 410)
G: caspase 8 (homo sapiens) (aka caspase 8)
H: caspase-9 (xenopus tropicalis) (aka caspase 9)
I: uqcc (homo sapiens) (aka ubiquinol-cytochrome c reductase complex assembly factor 1)
J: cytochrome c1 (homo sapiens) (aka cytochrome c1)
K: mitochondrially encoded cytochrome c oxidase iii (homo sapiens) (aka mitochondrially encoded cytochrome c oxidase iii)
L: apoptotic peptidase activating factor 1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
M: apaf-1 (xenopus tropicalis) (aka apoptotic peptidase activating factor 1)
N: cytochrome c, somatic (oryctolagus cuniculus) (aka cytochrome c, somatic)
O: None of the above. | [L; C; O] |
<Instruct>: Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1; cytochrome c; caspase-9]
<Options>: A: caspase 9 (homo sapiens) (aka caspase 9)
B: cytochrome c, somatic (homo sapiens) (aka cytochrome c, somatic)
C: casp-7 (homo sapiens) (aka caspase 7)
D: caspase-9 (mus musculus) (aka caspase 9)
E: apoptotic peptidase activating factor 1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
F: uqcc (homo sapiens) (aka ubiquinol-cytochrome c reductase complex assembly factor 1)
G: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
H: apak (homo sapiens) (aka zinc finger protein 420)
I: caspase-9 (xenopus tropicalis) (aka caspase 9)
J: succinate dehydrogenase complex subunit c (homo sapiens) (aka succinate dehydrogenase complex subunit c)
K: casp-8 (homo sapiens) (aka caspase 8)
L: cytochrome c1 (homo sapiens) (aka cytochrome c1)
M: cytochrome c (glycine max) (aka cytochrome c)
N: apaf-1 (xenopus tropicalis) (aka apoptotic peptidase activating factor 1)
O: apa-1 (homo sapiens) (aka zinc finger protein 410)
P: None of the above. | [E; B; A] |
<Instruct>: Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1; cytochrome c; caspase-9]
<Options>: A: apa-1 (homo sapiens) (aka zinc finger protein 410)
B: apaf1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
C: uqcc (homo sapiens) (aka ubiquinol-cytochrome c reductase complex assembly factor 1)
D: cytochrome c, somatic (homo sapiens) (aka cytochrome c, somatic)
E: caspase 7 (homo sapiens) (aka caspase 7)
F: caspase-9 (xenopus tropicalis) (aka caspase 9)
G: mitochondrially encoded cytochrome c oxidase iii (homo sapiens) (aka mitochondrially encoded cytochrome c oxidase iii)
H: caspase 8 (homo sapiens) (aka caspase 8)
I: succinate dehydrogenase complex subunit c (homo sapiens) (aka succinate dehydrogenase complex subunit c)
J: apaf-1 (xenopus tropicalis) (aka apoptotic peptidase activating factor 1)
K: cytochrome c1 (homo sapiens) (aka cytochrome c1)
L: caspase 9 (homo sapiens) (aka caspase 9)
M: apak (homo sapiens) (aka zinc finger protein 420)
N: apaf-3 (homo sapiens) (aka caspase 9)
O: caspase-9 (mus musculus) (aka caspase 9)
P: None of the above. | [B; D; L] |
<Instruct>: Given the context 'It has been shown that epigenetic silencing of the APAF-1 gene is a common event in several metastatic melanoma cells in vitro.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1]
<Options>: A: apa-1 (homo sapiens) (aka zinc finger protein 410)
B: apaf-3 (homo sapiens) (aka caspase 9)
C: apak (homo sapiens) (aka zinc finger protein 420)
D: apaf-1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
E: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
F: None of the above. | [D] |
<Instruct>: Given the context 'We determined, by Western blot, variation in the level of expression of APAF-1 in several human melanoma cell lines and, by immunohistochemistry, in a group of 106 histological samples including benign and malignant melanocytic lesions.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1]
<Options>: A: apak (homo sapiens) (aka zinc finger protein 420)
B: apa-1 (homo sapiens) (aka zinc finger protein 410)
C: apaf-3 (homo sapiens) (aka caspase 9)
D: apoptotic peptidase activating factor 1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
E: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
F: None of the above. | [D] |
<Instruct>: Given the context 'We observed APAF-1 down-regulation or loss of expression in two metastatic melanoma cell lines, compared to primary melanoma cell lines.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1]
<Options>: A: apaf-1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
B: apaf-3 (homo sapiens) (aka caspase 9)
C: apak (homo sapiens) (aka zinc finger protein 420)
D: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
E: apa-1 (homo sapiens) (aka zinc finger protein 410)
F: None of the above. | [A] |
<Instruct>: Given the context 'The immunohistochemical analysis revealed a significant difference in APAF-1 staining between nevi and melanomas.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1]
<Options>: A: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
B: apaf-3 (homo sapiens) (aka caspase 9)
C: apoptotic peptidase activating factor 1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
D: apak (homo sapiens) (aka zinc finger protein 420)
E: apa-1 (homo sapiens) (aka zinc finger protein 410)
F: None of the above. | [C] |
<Instruct>: Given the context 'The immunohistochemical analysis revealed a significant difference in APAF-1 staining between nevi and melanomas.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1]
<Options>: A: apak (homo sapiens) (aka zinc finger protein 420)
B: apaf-3 (homo sapiens) (aka caspase 9)
C: apa-1 (homo sapiens) (aka zinc finger protein 410)
D: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
E: None of the above. | [E] |
<Instruct>: Given the context 'In addition, we found a significant negative correlation between APAF-1 expression level and tumor thickness and between primary melanomas and metastases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1]
<Options>: A: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
B: apaf-1 (xenopus tropicalis) (aka apoptotic peptidase activating factor 1)
C: apaf3 (homo sapiens) (aka caspase 9)
D: apoptotic peptidase activating factor 1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
E: apak (homo sapiens) (aka zinc finger protein 420)
F: None of the above. | [D] |
<Instruct>: Given the context 'We conclude that loss of APAF-1 expression can be considered as an indicator of malignant transformation in melanoma.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [apaf-1]
<Options>: A: apaf-1 (drosophila melanogaster) (aka death-associated apaf1-related killer)
B: apaf1 (homo sapiens) (aka apoptotic peptidase activating factor 1)
C: apaf-3 (homo sapiens) (aka caspase 9)
D: apak (homo sapiens) (aka zinc finger protein 420)
E: apaf-1 (xenopus tropicalis) (aka apoptotic peptidase activating factor 1)
F: None of the above. | [B] |
<Instruct>: Given the context 'A human cDNA was cloned that encodes a DNA-binding protein (SATB1) that is expressed predominantly in thymus and binds selectively to the nuclear matrix/scaffold-associating DNAs (MARs/SARs).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb1 (rattus norvegicus) (aka satb homeobox 1)
B: satb homeobox 1 (homo sapiens) (aka satb homeobox 1)
C: satb2 (bos taurus) (aka satb homeobox 2)
D: satb1 (sus scrofa) (aka satb homeobox 1)
E: sat2 (bos taurus) (aka spermidine/spermine n1-acetyltransferase family member 2)
F: None of the above. | [B] |
<Instruct>: Given the context 'Missing nucleoside experiments showed that SATB1 selectively binds in a special AT-rich sequence context where one strand consists of mixed A's, T's, and C's, excluding G's (ATC sequences).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb1 (homo sapiens) (aka satb homeobox 1)
B: satb1 (sus scrofa) (aka satb homeobox 1)
C: satb2 (bos taurus) (aka satb homeobox 2)
D: satb1 (rattus norvegicus) (aka satb homeobox 1)
E: satb homeobox 1 (bos taurus) (aka satb homeobox 1)
F: None of the above. | [A] |
<Instruct>: Given the context 'When this feature is destroyed by mutation, SATB1 binding is greatly reduced even if the direct contact sequence remains intact.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb homeobox 1 (bos taurus) (aka satb homeobox 1)
B: satb1 antisense rna 1 (homo sapiens) (aka satb1 antisense rna 1)
C: sat1 (bos taurus) (aka spermidine/spermine n1-acetyltransferase 1)
D: satb1 (homo sapiens) (aka satb homeobox 1)
E: sat2 (bos taurus) (aka spermidine/spermine n1-acetyltransferase family member 2)
F: None of the above. | [D] |
<Instruct>: Given the context 'Conjunctional SATB1-binding sequences become stably unpaired in supercoiled DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb2 (bos taurus) (aka satb homeobox 2)
B: satb1 (rattus norvegicus) (aka satb homeobox 1)
C: satb1 (homo sapiens) (aka satb homeobox 1)
D: satb1 antisense rna 1 (homo sapiens) (aka satb1 antisense rna 1)
E: satb1 (sus scrofa) (aka satb homeobox 1)
F: None of the above. | [C] |
<Instruct>: Given the context 'Specific mutations that diminish the unwinding potential greatly reduce SATB1 binding.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb1 antisense rna 1 (homo sapiens) (aka satb1 antisense rna 1)
B: satb1 (sus scrofa) (aka satb homeobox 1)
C: satb2 (bos taurus) (aka satb homeobox 2)
D: satb1 (rattus norvegicus) (aka satb homeobox 1)
E: satb homeobox 1 (homo sapiens) (aka satb homeobox 1)
F: None of the above. | [E] |
<Instruct>: Given the context 'However, SATB1 does not bind single-stranded DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb1 (sus scrofa) (aka satb homeobox 1)
B: satb1 (rattus norvegicus) (aka satb homeobox 1)
C: satb2 (bos taurus) (aka satb homeobox 2)
D: sat1 (bos taurus) (aka spermidine/spermine n1-acetyltransferase 1)
E: satb1 (homo sapiens) (aka satb homeobox 1)
F: None of the above. | [E] |
<Instruct>: Given the context 'Chemical interference assays show that SATB1 binds along the minor groove with very little contact with the bases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: sat1 (bos taurus) (aka spermidine/spermine n1-acetyltransferase 1)
B: satb homeobox 1 (bos taurus) (aka satb homeobox 1)
C: satb2 (bos taurus) (aka satb homeobox 2)
D: satb1 (homo sapiens) (aka satb homeobox 1)
E: satb1 antisense rna 1 (homo sapiens) (aka satb1 antisense rna 1)
F: None of the above. | [D] |
<Instruct>: Given the context 'This suggests that SATB1 recognizes the ATC sequence indirectly through the altered sugar-phosphate backbone structure present in the double-stranded DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb1 (rattus norvegicus) (aka satb homeobox 1)
B: satb homeobox 1 (bos taurus) (aka satb homeobox 1)
C: satb1 (homo sapiens) (aka satb homeobox 1)
D: sat2 (bos taurus) (aka spermidine/spermine n1-acetyltransferase family member 2)
E: satb1 (sus scrofa) (aka satb homeobox 1)
F: None of the above. | [C] |
<Instruct>: Given the context 'This suggests that SATB1 recognizes the ATC sequence indirectly through the altered sugar-phosphate backbone structure present in the double-stranded DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [satb1]
<Options>: A: satb1 (sus scrofa) (aka satb homeobox 1)
B: satb homeobox 1 (bos taurus) (aka satb homeobox 1)
C: sat2 (bos taurus) (aka spermidine/spermine n1-acetyltransferase family member 2)
D: satb1 (rattus norvegicus) (aka satb homeobox 1)
E: None of the above. | [E] |
<Instruct>: Given the context 'Cloning and characterization of a human angiotensin II type 1 receptor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [angiotensin ii type 1 receptor]
<Options>: A: angiotensin ii receptor type 2 (homo sapiens) (aka angiotensin ii receptor type 2)
B: angiotensin ii receptor, type 1a (rattus norvegicus) (aka angiotensin ii receptor, type 1a)
C: at1br (homo sapiens) (aka angiotensin ii receptor type 1)
D: angiotensin ii receptor, type 1b (rattus norvegicus) (aka angiotensin ii receptor, type 1b)
E: None of the above. | [C] |
<Instruct>: Given the context 'A human liver cDNA library was screened using a rat type 1 angiotensin II receptor cDNA coding sequence as a probe.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [type 1 angiotensin ii receptor]
<Options>: A: angiotensin ii receptor type 2 (homo sapiens) (aka angiotensin ii receptor type 2)
B: angiotensin ii receptor, type 1b (rattus norvegicus) (aka angiotensin ii receptor, type 1b)
C: angiotensin ii receptor type 1 (homo sapiens) (aka angiotensin ii receptor type 1)
D: angiotensin ii receptor, type 1a (rattus norvegicus) (aka angiotensin ii receptor, type 1a)
E: None of the above. | [D] |
<Instruct>: Given the context 'Ligand binding studies of the cloned receptor expressed in COS cells suggested that it is pharmacologically a type 1 angiotensin II receptor subtype.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [type 1 angiotensin ii receptor]
<Options>: A: angiotensin ii receptor, type 1a (rattus norvegicus) (aka angiotensin ii receptor, type 1a)
B: angiotensin ii receptor, type 1b (rattus norvegicus) (aka angiotensin ii receptor, type 1b)
C: at1r (homo sapiens) (aka angiotensin ii receptor type 1)
D: angiotensin ii receptor type 2 (homo sapiens) (aka angiotensin ii receptor type 2)
E: None of the above. | [C] |
<Instruct>: Given the context 'A gene encoding a putative human RNA helicase, p54, has been cloned and mapped to the band q23.3 of chromosome 11.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [p54]
<Options>: A: p54 (rattus norvegicus) (aka nucleobindin 2)
B: p54 (homo sapiens) (fkbp prolyl isomerase 5 (homo sapiens)) (aka fkbp prolyl isomerase 5)
C: p54 (xenopus tropicalis) (aka dead-box helicase 6)
D: p64h1 (homo sapiens) (aka chloride intracellular channel 4)
E: p104 (homo sapiens) (aka natural killer cell triggering receptor)
F: None of the above. | [F] |
<Instruct>: Given the context 'The predicted amino acid sequence shares a striking homology (75% identical) with the female germline-specific RNA helicase ME31B gene of Drosophila.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [me31b]
<Options>: A: krt33b (mus musculus) (aka keratin 33b)
B: family with sequence similarity 131, member b (mus musculus) (aka family with sequence similarity 131, member b)
C: sec31 homolog b, copii coat complex component (mus musculus) (aka sec31 homolog b, copii coat complex component)
D: maternal expression at 31b (drosophila melanogaster) (aka maternal expression at 31b)
E: ces31l (mus musculus) (aka carboxylesterase 3b)
F: None of the above. | [D] |
<Instruct>: Given the context 'Unlike ME31B, however, the new gene expresses an abundant transcript in a large number of adult tissues and its 5' non-coding region was found split in a t(11;14)(q23.3;q32.3) cell line from a diffuse large B-cell lymphoma.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [me31b]
<Options>: A: krt33b (mus musculus) (aka keratin 33b)
B: maternal expression at 31b (drosophila melanogaster) (aka maternal expression at 31b)
C: ces31l (mus musculus) (aka carboxylesterase 3b)
D: tmem132b (mus musculus) (aka transmembrane protein 132b)
E: sec31b (mus musculus) (aka sec31 homolog b, copii coat complex component)
F: None of the above. | [B] |
<Instruct>: Given the context 'Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [n-myc]
<Options>: A: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
B: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
C: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
D: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
E: mycn proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
F: None of the above. | [E] |
<Instruct>: Given the context 'The gene termed heir-1 was localized to the neuroblastoma consensus deletion at 1p36.2-p36.12.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [heir-1]
<Options>: A: heir-1 (homo sapiens) (aka inhibitor of dna binding 3)
B: heew1 (homo sapiens) (aka ectopic p-granules 5 autophagy tethering factor)
C: heil1 (homo sapiens) (aka zbtb7c antisense rna 2)
D: hrt-1 (homo sapiens) (aka hes related family bhlh transcription factor with yrpw motif 1)
E: hef1 (homo sapiens) (aka neural precursor cell expressed, developmentally down-regulated 9)
F: None of the above. | [A] |
<Instruct>: Given the context 'Its predicted protein is 95.8% identical to the mouse HLH462 protein and has clear homology to the mouse Id and Drosophila emc proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hlh462; id; emc]
<Options>: A: lethal (1) hm452 (drosophila melanogaster) (aka lethal (1) hm452)
B: emc1 (homo sapiens) (aka er membrane protein complex subunit 1)
C: hlh462 (mus musculus) (aka inhibitor of dna binding 3)
D: er membrane complex subunit emc3 (saccharomyces cerevisiae s288c) (aka er membrane complex subunit emc3)
E: cg46462 (drosophila melanogaster) (aka uncharacterized protein)
F: lethal (1) g0462 (drosophila melanogaster) (aka lethal (1) g0462)
G: emc (drosophila melanogaster) (aka extra macrochaetae)
H: id1 (danio rerio) (aka inhibitor of dna binding 1, hlh protein)
I: iddpn (homo sapiens) (aka nudix hydrolase 2)
J: id (mus musculus) (aka atpase, class i, type 8b, member 2)
K: lethal (2) 46eh (drosophila melanogaster) (aka lethal (2) 46eh)
L: idx-1 (homo sapiens) (aka pancreatic and duodenal homeobox 1)
M: evc (mus musculus) (aka evc ciliary complex subunit 1)
N: iddam (homo sapiens) (aka chromodomain helicase dna binding protein 8)
O: emc3 (mus musculus) (aka er membrane protein complex subunit 3)
P: None of the above. | [C; J; G] |
<Instruct>: Given the context 'Its predicted protein is 95.8% identical to the mouse HLH462 protein and has clear homology to the mouse Id and Drosophila emc proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hlh462; id; emc]
<Options>: A: ids (homo sapiens) (aka iduronate 2-sulfatase)
B: iddmx (homo sapiens) (aka diabetes mellitus, insulin-dependent, x-linked, susceptibility to)
C: emcn (mus musculus) (aka endomucin)
D: hlh462 (mus musculus) (aka inhibitor of dna binding 3)
E: id (mus musculus) (aka atpase, class i, type 8b, member 2)
F: emc1 (homo sapiens) (aka er membrane protein complex subunit 1)
G: lethal (1) g0462 (drosophila melanogaster) (aka lethal (1) g0462)
H: id1 (danio rerio) (aka inhibitor of dna binding 1, hlh protein)
I: lethal (2) 46f4 (drosophila melanogaster) (aka lethal (2) 46f4)
J: id1 (homo sapiens) (aka inhibitor of dna binding 1)
K: lethal (1) hm452 (drosophila melanogaster) (aka lethal (1) hm452)
L: lethal (1) eshs46 (drosophila melanogaster) (aka lethal (1) eshs46)
M: emc (drosophila melanogaster) (aka extra macrochaetae)
N: emc1 (mus musculus) (aka er membrane protein complex subunit 1)
O: evc (mus musculus) (aka evc ciliary complex subunit 1)
P: None of the above. | [D; E; M] |
<Instruct>: Given the context 'Its predicted protein is 95.8% identical to the mouse HLH462 protein and has clear homology to the mouse Id and Drosophila emc proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hlh462; id; emc]
<Options>: A: emc (drosophila melanogaster) (aka extra macrochaetae)
B: emc-1 (caenorhabditis elegans) (aka er membrane protein complex subunit 1;wd_repeats_region domain-containing protein)
C: emc3 (mus musculus) (aka er membrane protein complex subunit 3)
D: iddhisd (homo sapiens) (aka transportin 2)
E: evc (mus musculus) (aka evc ciliary complex subunit 1)
F: iddmx (homo sapiens) (aka diabetes mellitus, insulin-dependent, x-linked, susceptibility to)
G: ids (homo sapiens) (aka iduronate 2-sulfatase)
H: zfp462 (xenopus laevis) (zinc finger protein 462 s homeolog (xenopus laevis)) (aka zinc finger protein 462 s homeolog)
I: iddam (homo sapiens) (aka chromodomain helicase dna binding protein 8)
J: lethal (1) hm442 (drosophila melanogaster) (aka lethal (1) hm442)
K: lethal (1) g0462 (drosophila melanogaster) (aka lethal (1) g0462)
L: cg46462 (drosophila melanogaster) (aka uncharacterized protein)
M: hlh462 (mus musculus) (aka inhibitor of dna binding 3)
N: emc-3 (caenorhabditis elegans) (aka er membrane protein complex subunit 3)
O: id (mus musculus) (aka atpase, class i, type 8b, member 2)
P: None of the above. | [M; O; A] |
<Instruct>: Given the context 'Heir-1 does not encode a basic DNA binding domain as found in basic HLH proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [heir-1]
<Options>: A: hin-1 (homo sapiens) (aka secretoglobin family 3a member 1)
B: heil1 (homo sapiens) (aka zbtb7c antisense rna 2)
C: heir-1 (homo sapiens) (aka inhibitor of dna binding 3)
D: heip1 (homo sapiens) (aka regulator of dna class i crossover intermediates 1)
E: heir-1 (xenopus laevis) (inhibitor of dna binding 3, hlh protein l homeolog (xenopus laevis)) (aka inhibitor of dna binding 3, hlh protein l homeolog)
F: None of the above. | [C] |
<Instruct>: Given the context 'Despite prominent heir-1 expression in adrenal medulla, which is a prime target for neuroblastomas, 10 out of 12 neuroblastoma-derived cell lines revealed very low levels of heir-1 mRNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [heir-1]
<Options>: A: hef1 (homo sapiens) (aka neural precursor cell expressed, developmentally down-regulated 9)
B: heip1 (homo sapiens) (aka regulator of dna class i crossover intermediates 1)
C: heir-1 (homo sapiens) (aka inhibitor of dna binding 3)
D: heed (homo sapiens) (aka embryonic ectoderm development)
E: hin-1 (homo sapiens) (aka secretoglobin family 3a member 1)
F: None of the above. | [C] |
<Instruct>: Given the context 'Low heir-1 expression was generally found in tumor cell lines with N-myc overexpression, whereas the two cell lines displaying high heir-1 levels did not overexpress N-myc.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [heir-1; n-myc]
<Options>: A: hrt-1 (homo sapiens) (aka hes related family bhlh transcription factor with yrpw motif 1)
B: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
C: hin-1 (homo sapiens) (aka secretoglobin family 3a member 1)
D: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
E: hef1 (homo sapiens) (aka neural precursor cell expressed, developmentally down-regulated 9)
F: heir-1 (homo sapiens) (aka inhibitor of dna binding 3)
G: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
H: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
I: heew1 (homo sapiens) (aka ectopic p-granules 5 autophagy tethering factor)
J: n-myc (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
K: None of the above. | [F; J] |
<Instruct>: Given the context 'Low heir-1 expression was generally found in tumor cell lines with N-myc overexpression, whereas the two cell lines displaying high heir-1 levels did not overexpress N-myc.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [heir-1; n-myc]
<Options>: A: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
B: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
C: n-myc (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
D: hrt-1 (homo sapiens) (aka hes related family bhlh transcription factor with yrpw motif 1)
E: heew1 (homo sapiens) (aka ectopic p-granules 5 autophagy tethering factor)
F: heir-1 (homo sapiens) (aka inhibitor of dna binding 3)
G: heir-1 (xenopus laevis) (inhibitor of dna binding 3, hlh protein l homeolog (xenopus laevis)) (aka inhibitor of dna binding 3, hlh protein l homeolog)
H: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
I: heed (homo sapiens) (aka embryonic ectoderm development)
J: n-myc (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
K: None of the above. | [F; J] |
<Instruct>: Given the context 'We conclude that heir-1 expression is reduced specifically in the majority of neuroblastomas and suggest an inverse correlation between heir-1 and N-myc expression in neuroblastoma tumors and in embryonic development.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [heir-1; n-myc]
<Options>: A: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
B: nmyc (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
C: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
D: heir-1 (homo sapiens) (aka inhibitor of dna binding 3)
E: n-myc (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: hef1 (homo sapiens) (aka neural precursor cell expressed, developmentally down-regulated 9)
G: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
H: heed (homo sapiens) (aka embryonic ectoderm development)
I: hrt-1 (homo sapiens) (aka hes related family bhlh transcription factor with yrpw motif 1)
J: he1 (homo sapiens) (aka npc intracellular cholesterol transporter 2)
K: None of the above. | [D; B] |
<Instruct>: Given the context 'We conclude that heir-1 expression is reduced specifically in the majority of neuroblastomas and suggest an inverse correlation between heir-1 and N-myc expression in neuroblastoma tumors and in embryonic development.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [heir-1; n-myc]
<Options>: A: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
B: heir-1 (homo sapiens) (aka inhibitor of dna binding 3)
C: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
D: hef1 (homo sapiens) (aka neural precursor cell expressed, developmentally down-regulated 9)
E: heil1 (homo sapiens) (aka zbtb7c antisense rna 2)
F: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
G: he1 (homo sapiens) (aka npc intracellular cholesterol transporter 2)
H: hin-1 (homo sapiens) (aka secretoglobin family 3a member 1)
I: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
J: n-myc (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
K: None of the above. | [B; J] |
<Instruct>: Given the context 'Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hnrnp u]
<Options>: A: hnrnpup1 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u pseudogene 1)
B: hnrpu (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
C: hnrnpu (bos taurus) (aka heterogeneous nuclear ribonucleoprotein u)
D: heterogeneous nuclear ribonucleoprotein u (mus musculus) (aka heterogeneous nuclear ribonucleoprotein u)
E: hnrnpu (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
F: None of the above. | [B] |
<Instruct>: Given the context 'The hnRNP U protein is an abundant nucleoplasmic phosphoprotein that is the largest of the major hnRNP proteins (120 kDa by SDS-PAGE).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hnrnp u]
<Options>: A: hnrnpu (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
B: heterogeneous nuclear ribonucleoprotein u (bos taurus) (aka heterogeneous nuclear ribonucleoprotein u)
C: hnrnpu (mus musculus) (aka heterogeneous nuclear ribonucleoprotein u)
D: hnrnp u (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
E: hnrnpup1 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u pseudogene 1)
F: None of the above. | [D] |
<Instruct>: Given the context 'HnRNP U binds pre-mRNA in vivo and binds both RNA and ssDNA in vitro.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hnrnp u]
<Options>: A: hnrnpu (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
B: hnrnpup1 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u pseudogene 1)
C: hnrnpu (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
D: heterogeneous nuclear ribonucleoprotein u (bos taurus) (aka heterogeneous nuclear ribonucleoprotein u)
E: heterogeneous nuclear ribonucleoprotein u (mus musculus) (aka heterogeneous nuclear ribonucleoprotein u)
F: None of the above. | [A] |
<Instruct>: Given the context 'HnRNP U binds pre-mRNA in vivo and binds both RNA and ssDNA in vitro.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hnrnp u]
<Options>: A: heterogeneous nuclear ribonucleoprotein u (bos taurus) (aka heterogeneous nuclear ribonucleoprotein u)
B: hnrnpu (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
C: heterogeneous nuclear ribonucleoprotein u (mus musculus) (aka heterogeneous nuclear ribonucleoprotein u)
D: hnrnpup1 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u pseudogene 1)
E: None of the above. | [E] |
<Instruct>: Given the context 'Here we describe the cloning and sequencing of a cDNA encoding the hnRNP U protein, the determination of its amino acid sequence and the delineation of a region in this protein that confers RNA binding.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hnrnp u]
<Options>: A: hnrnpu (bos taurus) (aka heterogeneous nuclear ribonucleoprotein u)
B: hnrnpu (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
C: hnrnpu (mus musculus) (aka heterogeneous nuclear ribonucleoprotein u)
D: hnrnp u (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
E: hnrnpup1 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u pseudogene 1)
F: None of the above. | [D] |
<Instruct>: Given the context 'The predicted amino acid sequence of hnRNP U contains 806 amino acids (88,939 Daltons), and shows no extensive homology to any known proteins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hnrnp u]
<Options>: A: hnrnpu (mus musculus) (aka heterogeneous nuclear ribonucleoprotein u)
B: hnrnpu (bos taurus) (aka heterogeneous nuclear ribonucleoprotein u)
C: hnrnpu (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
D: hnrnpup1 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u pseudogene 1)
E: hnrpu (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
F: None of the above. | [E] |
<Instruct>: Given the context 'Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cytoskeletal protein 4.1]
<Options>: A: erythrocyte membrane protein band 4.1 (bos taurus) (aka erythrocyte membrane protein band 4.1)
B: erythrocyte membrane protein band 4.1-like 1 (xenopus tropicalis) (aka erythrocyte membrane protein band 4.1-like 1)
C: erythrocyte membrane protein band 4.1 (xenopus tropicalis) (aka erythrocyte membrane protein band 4.1)
D: erythrocyte membrane protein band 4.1 (homo sapiens) (aka erythrocyte membrane protein band 4.1)
E: erythrocyte membrane protein band 4.1 like 4b (homo sapiens) (aka erythrocyte membrane protein band 4.1 like 4b)
F: None of the above. | [D] |
<Instruct>: Given the context 'We screened human megakaryoblastic cell line (MEG-01) an umbilical vein endothelial cell cDNA libraries to obtain a 3.7-kilobase cDNA designated PTPase MEG.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ptpase meg]
<Options>: A: ptpmeg (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 4)
B: ptpe (mus musculus) (aka protein tyrosine phosphatase receptor type e)
C: ptp-pest (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 12)
D: ptpmeg1 (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 4)
E: ptp-meg (drosophila melanogaster) (aka protein tyrosine phosphatase meg)
F: None of the above. | [D] |
<Instruct>: Given the context 'PTPase MEG cDNA contains an open reading frame of 926 amino acids.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [ptpase meg]
<Options>: A: ptpe (mus musculus) (aka protein tyrosine phosphatase receptor type e)
B: ptpmeg (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 4)
C: phosphoglycolate phosphatase (mus musculus) (aka phosphoglycolate phosphatase)
D: ptp-meg (drosophila melanogaster) (aka protein tyrosine phosphatase meg)
E: ptpmeg (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 4)
F: None of the above. | [B] |
<Instruct>: Given the context 'The amino-terminal region (amino acids 31-367) is 45% identical to the amino terminus of human erythrocyte protein 4.1, a cytoskeletal protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [erythrocyte protein 4.1]
<Options>: A: erythrocyte membrane protein band 4.1 (homo sapiens) (aka erythrocyte membrane protein band 4.1)
B: erythrocyte membrane protein band 4.1 like 3 (homo sapiens) (aka erythrocyte membrane protein band 4.1 like 3)
C: erythrocyte membrane protein band 4.1 like 4a (homo sapiens) (aka erythrocyte membrane protein band 4.1 like 4a)
D: erythrocyte membrane protein band 4.2 (homo sapiens) (aka erythrocyte membrane protein band 4.2)
E: erythrocyte membrane protein band 4.1 like 5 (homo sapiens) (aka erythrocyte membrane protein band 4.1 like 5)
F: None of the above. | [A] |
<Instruct>: Given the context 'The receptor for ciliary neurotrophic factor.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [receptor for ciliary neurotrophic factor]
<Options>: A: ciliary neurotrophic factor receptor (homo sapiens) (aka ciliary neurotrophic factor receptor)
B: ciliary neurotrophic factor receptor (bos taurus) (aka ciliary neurotrophic factor receptor)
C: ciliary neurotrophic factor receptor (xenopus tropicalis) (aka ciliary neurotrophic factor receptor)
D: ciliary neurotrophic factor receptor (oryctolagus cuniculus) (aka ciliary neurotrophic factor receptor)
E: ciliary neurotrophic factor receptor (sus scrofa) (aka ciliary neurotrophic factor receptor)
F: None of the above. | [A] |
<Instruct>: Given the context 'A " tagged-ligand panning " procedure was used to clone a receptor for ciliary neurotrophic factor (CNTF).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [receptor for ciliary neurotrophic factor; cntf]
<Options>: A: ciliary neurotrophic factor receptor (rattus norvegicus) (aka ciliary neurotrophic factor receptor)
B: cnt1 (homo sapiens) (aka solute carrier family 28 member 1)
C: ntn1r1 (homo sapiens) (aka dcc netrin 1 receptor)
D: cntf (bos taurus) (aka ciliary neurotrophic factor)
E: ciliary neurotrophic factor receptor (homo sapiens) (aka ciliary neurotrophic factor receptor)
F: ciliary neurotrophic factor receptor (danio rerio) (aka ciliary neurotrophic factor receptor)
G: cntn1 (homo sapiens) (aka contactin 1)
H: ciliary neurotrophic factor (homo sapiens) (aka ciliary neurotrophic factor)
I: cntfr (homo sapiens) (aka ciliary neurotrophic factor receptor)
J: ciliary neurotrophic factor receptor (oryctolagus cuniculus) (aka ciliary neurotrophic factor receptor)
K: None of the above. | [E; H] |
<Instruct>: Given the context 'A " tagged-ligand panning " procedure was used to clone a receptor for ciliary neurotrophic factor (CNTF).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [receptor for ciliary neurotrophic factor; cntf]
<Options>: A: ckr1 (homo sapiens) (aka c-c motif chemokine receptor 1)
B: ciliary neurotrophic factor receptor (oryctolagus cuniculus) (aka ciliary neurotrophic factor receptor)
C: ciliary neurotrophic factor receptor (homo sapiens) (aka ciliary neurotrophic factor receptor)
D: ciliary neurotrophic factor receptor (danio rerio) (aka ciliary neurotrophic factor receptor)
E: cellular communication network factor 1 (homo sapiens) (aka cellular communication network factor 1)
F: cntfr (homo sapiens) (aka ciliary neurotrophic factor receptor)
G: cnt1 (homo sapiens) (aka solute carrier family 28 member 1)
H: hcntf (homo sapiens) (aka ciliary neurotrophic factor)
I: cntf (xenopus tropicalis) (aka ciliary neurotrophic factor)
J: ciliary neurotrophic factor receptor (bos taurus) (aka ciliary neurotrophic factor receptor)
K: None of the above. | [C; H] |
<Instruct>: Given the context 'The CNTF receptor has a structure unrelated to the receptors utilized by the nerve growth factor family of neurotrophic molecules, but instead is most homologous to the receptor for a cytokine, interleukin-6.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cntf receptor; interleukin-6]
<Options>: A: ciliary neurotrophic factor receptor (gallus gallus) (aka ciliary neurotrophic factor receptor)
B: il7 (homo sapiens) (aka interleukin 7)
C: cntfr (rattus norvegicus) (aka ciliary neurotrophic factor receptor)
D: ntn1r1 (homo sapiens) (aka dcc netrin 1 receptor)
E: cntfr (homo sapiens) (aka ciliary neurotrophic factor receptor)
F: hbgf-6 (homo sapiens) (aka fibroblast growth factor 6)
G: npffr1 (rattus norvegicus) (aka neuropeptide ff receptor 1)
H: interleukin 6 (homo sapiens) (aka interleukin 6)
I: lif interleukin 6 family cytokine (homo sapiens) (aka lif interleukin 6 family cytokine)
J: None of the above. | [E; H] |
<Instruct>: Given the context 'The CNTF receptor has a structure unrelated to the receptors utilized by the nerve growth factor family of neurotrophic molecules, but instead is most homologous to the receptor for a cytokine, interleukin-6.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cntf receptor; interleukin-6]
<Options>: A: ciliary neurotrophic factor receptor (danio rerio) (aka ciliary neurotrophic factor receptor)
B: cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens)) (aka lif interleukin 6 family cytokine)
C: cntfr (rattus norvegicus) (aka ciliary neurotrophic factor receptor)
D: interleukin 7 (homo sapiens) (aka interleukin 7)
E: ciliary neurotrophic factor receptor (gallus gallus) (aka ciliary neurotrophic factor receptor)
F: cntfr (homo sapiens) (aka ciliary neurotrophic factor receptor)
G: interleukin 6 (homo sapiens) (aka interleukin 6)
H: hbgf-6 (homo sapiens) (aka fibroblast growth factor 6)
I: npffr1 (rattus norvegicus) (aka neuropeptide ff receptor 1)
J: None of the above. | [F; G] |
<Instruct>: Given the context 'This similarity suggestes that the CNTF receptor, like the interleukin-6 receptor, requires a second, signal-transducing component.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cntf receptor; interleukin-6 receptor]
<Options>: A: cntfr (homo sapiens) (aka ciliary neurotrophic factor receptor)
B: cntfr (rattus norvegicus) (aka ciliary neurotrophic factor receptor)
C: interleukin 6 receptor (homo sapiens) (aka interleukin 6 receptor)
D: ciliary neurotrophic factor receptor (xenopus tropicalis) (aka ciliary neurotrophic factor receptor)
E: ciliary neurotrophic factor receptor (gallus gallus) (aka ciliary neurotrophic factor receptor)
F: il-6rb (homo sapiens) (aka interleukin 6 cytokine family signal transducer)
G: il6rl1 (homo sapiens) (aka interleukin 6 receptor pseudogene 1)
H: ntn1r1 (homo sapiens) (aka dcc netrin 1 receptor)
I: None of the above. | [A; C] |
<Instruct>: Given the context 'This similarity suggestes that the CNTF receptor, like the interleukin-6 receptor, requires a second, signal-transducing component.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cntf receptor; interleukin-6 receptor]
<Options>: A: il6rl1 (homo sapiens) (aka interleukin 6 receptor pseudogene 1)
B: cntfr (homo sapiens) (aka ciliary neurotrophic factor receptor)
C: ciliary neurotrophic factor receptor (danio rerio) (aka ciliary neurotrophic factor receptor)
D: il6st (homo sapiens) (aka interleukin 6 cytokine family signal transducer)
E: il-6ra (homo sapiens) (aka interleukin 6 receptor)
F: ciliary neurotrophic factor receptor (rattus norvegicus) (aka ciliary neurotrophic factor receptor)
G: ciliary neurotrophic factor receptor (xenopus tropicalis) (aka ciliary neurotrophic factor receptor)
H: ciliary neurotrophic factor receptor (gallus gallus) (aka ciliary neurotrophic factor receptor)
I: None of the above. | [B; E] |
<Instruct>: Given the context 'In contrast to all known receptors, the CNTF receptor is anchored to cell membranes by a glycosyl-phosphatidylinositol linkage.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cntf receptor]
<Options>: A: ciliary neurotrophic factor receptor (gallus gallus) (aka ciliary neurotrophic factor receptor)
B: ciliary neurotrophic factor receptor (xenopus tropicalis) (aka ciliary neurotrophic factor receptor)
C: ntn1r1 (homo sapiens) (aka dcc netrin 1 receptor)
D: ciliary neurotrophic factor receptor (danio rerio) (aka ciliary neurotrophic factor receptor)
E: cntfr (homo sapiens) (aka ciliary neurotrophic factor receptor)
F: None of the above. | [E] |
<Instruct>: Given the context 'In contrast to all known receptors, the CNTF receptor is anchored to cell membranes by a glycosyl-phosphatidylinositol linkage.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cntf receptor]
<Options>: A: ntn1r1 (homo sapiens) (aka dcc netrin 1 receptor)
B: ciliary neurotrophic factor receptor (gallus gallus) (aka ciliary neurotrophic factor receptor)
C: ciliary neurotrophic factor receptor (danio rerio) (aka ciliary neurotrophic factor receptor)
D: ciliary neurotrophic factor receptor (xenopus tropicalis) (aka ciliary neurotrophic factor receptor)
E: None of the above. | [E] |
<Instruct>: Given the context 'A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cellular retinol-binding protein type ii; rxr]
<Options>: A: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
B: rxrc (homo sapiens) (aka retinoid x receptor gamma)
C: crabp-ii (homo sapiens) (cellular retinoic acid binding protein 2 (homo sapiens)) (aka cellular retinoic acid binding protein 2)
D: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
E: rxra (homo sapiens) (aka retinoid x receptor alpha)
F: retinol binding protein 2 (bos taurus) (aka retinol binding protein 2)
G: retinol binding protein 1 (homo sapiens) (aka retinol binding protein 1)
H: rxrbeta (homo sapiens) (aka retinoid x receptor beta)
I: retinol binding protein 2 (homo sapiens) (aka retinol binding protein 2)
J: retinol binding protein 3 (homo sapiens) (aka retinol binding protein 3)
K: None of the above. | [I; E] |
<Instruct>: Given the context 'A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cellular retinol-binding protein type ii; rxr]
<Options>: A: rxralpha (homo sapiens) (aka retinoid x receptor alpha)
B: retinol binding protein 1 (homo sapiens) (aka retinol binding protein 1)
C: rxrb (homo sapiens) (aka retinoid x receptor beta)
D: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
E: rbp2 (homo sapiens) (retinol binding protein 2 (homo sapiens)) (aka retinol binding protein 2)
F: rxrg (homo sapiens) (aka retinoid x receptor gamma)
G: retinol binding protein 2 (bos taurus) (aka retinol binding protein 2)
H: retinol binding protein 7 (homo sapiens) (aka retinol binding protein 7)
I: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
J: retinol binding protein 3 (homo sapiens) (aka retinol binding protein 3)
K: None of the above. | [E; A] |
<Instruct>: Given the context 'The vitamin A derivative retinoic acid exerts its effects on transcription through two distinct classes of nuclear receptors, the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [retinoid x receptor; rxr]
<Options>: A: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
B: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
C: rxrg (homo sapiens) (aka retinoid x receptor gamma)
D: retinoid x receptor beta (homo sapiens) (aka retinoid x receptor beta)
E: rxralpha (homo sapiens) (aka retinoid x receptor alpha)
F: retinoid x receptor gamma (homo sapiens) (aka retinoid x receptor gamma)
G: retinoid x receptor alpha (xenopus tropicalis) (aka retinoid x receptor alpha)
H: rar related orphan receptor a (homo sapiens) (aka rar related orphan receptor a)
I: rxrb (homo sapiens) (aka retinoid x receptor beta)
J: None of the above. | [E; E] |
<Instruct>: Given the context 'The vitamin A derivative retinoic acid exerts its effects on transcription through two distinct classes of nuclear receptors, the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [retinoid x receptor; rxr]
<Options>: A: retinoid x receptor gamma (homo sapiens) (aka retinoid x receptor gamma)
B: lxra (homo sapiens) (aka nuclear receptor subfamily 1 group h member 3)
C: rxralpha (homo sapiens) (aka retinoid x receptor alpha)
D: rxrc (homo sapiens) (aka retinoid x receptor gamma)
E: rxr-beta (homo sapiens) (aka retinoid x receptor beta)
F: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
G: retinoid x receptor alpha (xenopus tropicalis) (aka retinoid x receptor alpha)
H: rar related orphan receptor a (homo sapiens) (aka rar related orphan receptor a)
I: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
J: None of the above. | [C; C] |
<Instruct>: Given the context 'We provide evidence that expression of the gene for cellular retinol-binding protein type II (CRBPII), a key protein in the intestinal absorption of vitamin A, is dramatically up-regulated by retinoic acid in the presence of RXR but not RAR.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cellular retinol-binding protein type ii; crbpii; rxr]
<Options>: A: retinol binding protein 2 (xenopus tropicalis) (aka retinol binding protein 2)
B: retinol binding protein 7 (homo sapiens) (aka retinol binding protein 7)
C: crbp-iii (homo sapiens) (aka retinol binding protein 5)
D: retinol binding protein 1 (homo sapiens) (aka retinol binding protein 1)
E: crabp-ii (homo sapiens) (cellular retinoic acid binding protein 2 (homo sapiens)) (aka cellular retinoic acid binding protein 2)
F: crabp-ii (homo sapiens) (retinol binding protein 2 (homo sapiens)) (aka retinol binding protein 2)
G: rxrb (homo sapiens) (aka retinoid x receptor beta)
H: crbp (homo sapiens) (aka retinol binding protein 1)
I: retinol binding protein 5 (homo sapiens) (aka retinol binding protein 5)
J: rxrg (homo sapiens) (aka retinoid x receptor gamma)
K: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
L: rxr-alpha (homo sapiens) (aka retinoid x receptor alpha)
M: crbpiv (homo sapiens) (aka retinol binding protein 7)
N: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
O: None of the above. | [F; F; L] |
<Instruct>: Given the context 'We provide evidence that expression of the gene for cellular retinol-binding protein type II (CRBPII), a key protein in the intestinal absorption of vitamin A, is dramatically up-regulated by retinoic acid in the presence of RXR but not RAR.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cellular retinol-binding protein type ii; crbpii; rxr]
<Options>: A: rxra (homo sapiens) (aka retinoid x receptor alpha)
B: rxr-beta (homo sapiens) (aka retinoid x receptor beta)
C: rxrg (homo sapiens) (aka retinoid x receptor gamma)
D: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
E: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
F: crbp-iii (homo sapiens) (aka retinol binding protein 5)
G: crabp-ii (homo sapiens) (retinol binding protein 2 (homo sapiens)) (aka retinol binding protein 2)
H: retinol binding protein 3 (homo sapiens) (aka retinol binding protein 3)
I: crbp1 (homo sapiens) (aka retinol binding protein 1)
J: crbpiv (homo sapiens) (aka retinol binding protein 7)
K: crabp-ii (homo sapiens) (cellular retinoic acid binding protein 2 (homo sapiens)) (aka cellular retinoic acid binding protein 2)
L: retinol binding protein 5 (homo sapiens) (aka retinol binding protein 5)
M: retinol binding protein 7 (homo sapiens) (aka retinol binding protein 7)
N: None of the above. | [G; G; A] |
<Instruct>: Given the context 'We provide evidence that expression of the gene for cellular retinol-binding protein type II (CRBPII), a key protein in the intestinal absorption of vitamin A, is dramatically up-regulated by retinoic acid in the presence of RXR but not RAR.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cellular retinol-binding protein type ii; crbpii; rxr]
<Options>: A: crabp-ii (homo sapiens) (cellular retinoic acid binding protein 2 (homo sapiens)) (aka cellular retinoic acid binding protein 2)
B: crabp-ii (homo sapiens) (retinol binding protein 2 (homo sapiens)) (aka retinol binding protein 2)
C: retinol binding protein 5 (homo sapiens) (aka retinol binding protein 5)
D: crbp-iii (homo sapiens) (aka retinol binding protein 5)
E: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
F: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
G: crbp (homo sapiens) (aka retinol binding protein 1)
H: retinol binding protein 2 (bos taurus) (aka retinol binding protein 2)
I: rxralpha (homo sapiens) (aka retinoid x receptor alpha)
J: rxrg (homo sapiens) (aka retinoid x receptor gamma)
K: retinol binding protein 1 (homo sapiens) (aka retinol binding protein 1)
L: crbpiv (homo sapiens) (aka retinol binding protein 7)
M: rxrb (homo sapiens) (aka retinoid x receptor beta)
N: None of the above. | [B; B; I] |
<Instruct>: Given the context 'This regulation is conferred through a specific cis element in the CRBPII promoter that contains five nearly perfect tandem repeats of the sequence AGGTCA spaced by a single nucleotide.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [crbpii]
<Options>: A: crbpiii (homo sapiens) (aka retinol binding protein 5)
B: crbpiv (homo sapiens) (aka retinol binding protein 7)
C: crabp-ii (homo sapiens) (cellular retinoic acid binding protein 2 (homo sapiens)) (aka cellular retinoic acid binding protein 2)
D: crbpii (homo sapiens) (aka retinol binding protein 2)
E: crbpi (homo sapiens) (aka retinol binding protein 1)
F: None of the above. | [D] |
<Instruct>: Given the context 'The discovery of this new RX response element provides a means for distinguishing between the two retinoid receptor systems and suggests that an RXR-mediated pathway exists for modulating vitamin A metabolism.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rxr]
<Options>: A: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
B: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
C: rxrb (homo sapiens) (aka retinoid x receptor beta)
D: rxrc (homo sapiens) (aka retinoid x receptor gamma)
E: rxr-alpha (homo sapiens) (aka retinoid x receptor alpha)
F: None of the above. | [E] |
<Instruct>: Given the context 'We have isolated a mouse cDNA of 5.7 kb, encoding a new member of the family of receptor-like protein tyrosine phosphatases, termed mRPTP mu.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrptp mu]
<Options>: A: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
B: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
C: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
D: mtrpol (mus musculus) (aka polymerase (rna) mitochondrial (dna directed))
E: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
F: None of the above. | [C] |
<Instruct>: Given the context 'We have isolated a mouse cDNA of 5.7 kb, encoding a new member of the family of receptor-like protein tyrosine phosphatases, termed mRPTP mu.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrptp mu]
<Options>: A: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
B: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
C: mtrpol (mus musculus) (aka polymerase (rna) mitochondrial (dna directed))
D: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
E: None of the above. | [E] |
<Instruct>: Given the context 'In addition, we have cloned the human homologue, hRPTP mu, which shows 98.7% amino acid identity to mRPTP mu.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hrptp mu; mrptp mu]
<Options>: A: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
B: r-ptp-u (homo sapiens) (aka protein tyrosine phosphatase receptor type u)
C: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
D: mrptprho (mus musculus) (aka protein tyrosine phosphatase receptor type t)
E: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
F: r-ptp-u (mus musculus) (aka protein tyrosine phosphatase receptor type u)
G: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
H: None of the above. | [C; E] |
<Instruct>: Given the context 'In addition, we have cloned the human homologue, hRPTP mu, which shows 98.7% amino acid identity to mRPTP mu.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hrptp mu; mrptp mu]
<Options>: A: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
B: mtrpol (mus musculus) (aka polymerase (rna) mitochondrial (dna directed))
C: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
D: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
E: r-ptp-u (mus musculus) (aka protein tyrosine phosphatase receptor type u)
F: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
G: r-ptp-u (homo sapiens) (aka protein tyrosine phosphatase receptor type u)
H: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
I: hprt (mus musculus) (aka hypoxanthine phosphoribosyltransferase 1)
J: r-ptp-h (mus musculus) (aka protein tyrosine phosphatase receptor type h)
K: None of the above. | [C; A] |
<Instruct>: Given the context 'The predicted mRPTP mu protein consists of a 722 amino acid extracellular region, containing 13 potential N-glycosylation sites, a single transmembrane domain and a 688 amino acid intracellular part containing 2 tandem repeats homologous to the catalytic domains of other tyrosine phosphatases.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrptp mu]
<Options>: A: mrptprho (mus musculus) (aka protein tyrosine phosphatase receptor type t)
B: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
C: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
D: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
E: mtrpol (mus musculus) (aka polymerase (rna) mitochondrial (dna directed))
F: None of the above. | [D] |
<Instruct>: Given the context 'Transfection of the mRPTP mu cDNA into COS cells results in the synthesis of a protein with an apparent Mr of 195,000, as detected in immunoblots using an antipeptide antibody.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrptp mu]
<Options>: A: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
B: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
C: trnp (mus musculus) (trna proline, mitochondrial (mus musculus)) (aka trna proline, mitochondrial)
D: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
E: r-ptp-u (mus musculus) (aka protein tyrosine phosphatase receptor type u)
F: None of the above. | [D] |
<Instruct>: Given the context 'The human RPTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rptp mu]
<Options>: A: rptpu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
B: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
C: protein tyrosine phosphatase receptor type u (homo sapiens) (aka protein tyrosine phosphatase receptor type u)
D: ptp (mus musculus) (protein tyrosine phosphatase receptor type u (mus musculus)) (aka protein tyrosine phosphatase receptor type u)
E: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
F: None of the above. | [A] |
<Instruct>: Given the context 'Cytotoxic lymphocyte maturation factor (CLMF) is a disulfide-bonded heterodimeric lymphokine that (i) acts as a growth factor for activated T cells independent of interleukin 2 and (ii) synergizes with suboptimal concentrations of interleukin 2 to induce lymphokine-activated killer cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [interleukin 2]
<Options>: A: il22 (homo sapiens) (aka interleukin 22)
B: csf2 (homo sapiens) (aka colony stimulating factor 2)
C: il-2 (homo sapiens) (aka interleukin 2)
D: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
E: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
F: None of the above. | [C] |
<Instruct>: Given the context 'Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; ox45; blast-1]
<Options>: A: bcm-1 (mus musculus) (aka cd48 antigen)
B: hcpeb-1 (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
C: bcrm1 (homo sapiens) (aka sideroflexin 4)
D: blast (homo sapiens) (aka cd48 molecule)
E: kit ligand (homo sapiens) (aka kit ligand)
F: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
G: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
H: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
I: of45 (rattus norvegicus) (aka matrix extracellular phosphoglycoprotein)
J: or4c45 (homo sapiens) (aka olfactory receptor family 4 subfamily c member 45 (gene/pseudogene))
K: vacuolar protein sorting 45 homolog (oryctolagus cuniculus) (aka vacuolar protein sorting 45 homolog)
L: g protein-coupled receptor 45 (oryctolagus cuniculus) (aka g protein-coupled receptor 45)
M: gpr45 (rattus norvegicus) (aka g protein-coupled receptor 45)
N: bsf-1 (homo sapiens) (aka interleukin 4)
O: None of the above. | [A; A; A] |
<Instruct>: Given the context 'Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; ox45; blast-1]
<Options>: A: bcm-1 (mus musculus) (aka cd48 antigen)
B: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
C: g protein-coupled receptor 45 (rattus norvegicus) (aka g protein-coupled receptor 45)
D: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: bsf-1 (homo sapiens) (aka interleukin 4)
G: g protein-coupled receptor 45 (oryctolagus cuniculus) (aka g protein-coupled receptor 45)
H: of45 (rattus norvegicus) (aka matrix extracellular phosphoglycoprotein)
I: blast1 (homo sapiens) (aka cd48 molecule)
J: vacuolar protein sorting 45 homolog (oryctolagus cuniculus) (aka vacuolar protein sorting 45 homolog)
K: bm-001 (homo sapiens) (aka cyclin l1)
L: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
M: gpr45 (homo sapiens) (aka g protein-coupled receptor 45)
N: blast-2 (homo sapiens) (aka fc epsilon receptor ii)
O: None of the above. | [A; A; A] |
<Instruct>: Given the context 'Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; ox45; blast-1]
<Options>: A: hcpeb-1 (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
B: blast-2 (homo sapiens) (aka fc epsilon receptor ii)
C: kit ligand (homo sapiens) (aka kit ligand)
D: gpr45 (rattus norvegicus) (aka g protein-coupled receptor 45)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: bcm1 (mus musculus) (aka cd48 antigen)
G: or4c45 (homo sapiens) (aka olfactory receptor family 4 subfamily c member 45 (gene/pseudogene))
H: olr45 (rattus norvegicus) (aka olfactory receptor family 52 subfamily k member 2)
I: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
J: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
K: bm-001 (homo sapiens) (aka cyclin l1)
L: g protein-coupled receptor 45 (oryctolagus cuniculus) (aka g protein-coupled receptor 45)
M: gpr45 (homo sapiens) (aka g protein-coupled receptor 45)
N: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
O: None of the above. | [F; F; F] |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; cd2; lfa3]
<Options>: A: cd2 (homo sapiens) (aka cd2 molecule)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
D: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
E: cd228 (homo sapiens) (aka melanotransferrin)
F: lfa-3 (homo sapiens) (aka cd58 molecule)
G: cd21 (homo sapiens) (aka complement c3d receptor 2)
H: lfa-2 (homo sapiens) (aka cd2 molecule)
I: bcm-1 (mus musculus) (aka cd48 antigen)
J: cd22 (homo sapiens) (aka cd22 molecule)
K: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
L: lfa1a (homo sapiens) (aka integrin subunit alpha l)
M: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
N: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
O: itga3 (homo sapiens) (aka integrin subunit alpha 3)
P: None of the above. | [B; A; F] |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; cd2; lfa3]
<Options>: A: bcm-1 (mus musculus) (aka cd48 antigen)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
D: lfa-2 (homo sapiens) (aka cd2 molecule)
E: lfa-3 (homo sapiens) (aka cd58 molecule)
F: cd21 (homo sapiens) (aka complement c3d receptor 2)
G: cd22 (homo sapiens) (aka cd22 molecule)
H: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
I: lfa1a (homo sapiens) (aka integrin subunit alpha l)
J: cd228 (homo sapiens) (aka melanotransferrin)
K: itga3 (homo sapiens) (aka integrin subunit alpha 3)
L: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
M: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
N: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
O: None of the above. | [B; O; E] |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; cd2; lfa3]
<Options>: A: cd2 (gallus gallus) (aka cd2 molecule)
B: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
C: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
D: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
E: bcrm1 (homo sapiens) (aka sideroflexin 4)
F: leu-3 (homo sapiens) (aka cd4 molecule)
G: bcm1 (homo sapiens) (aka cd48 molecule)
H: cd21 (homo sapiens) (aka complement c3d receptor 2)
I: cd22 (homo sapiens) (aka cd22 molecule)
J: cd11a (homo sapiens) (aka integrin subunit alpha l)
K: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
L: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
M: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
N: lfa3 (homo sapiens) (aka cd58 molecule)
O: cd2 (homo sapiens) (aka cd2 molecule)
P: None of the above. | [G; O; N] |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; cd2; lfa3]
<Options>: A: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
B: lfa3 (homo sapiens) (aka cd58 molecule)
C: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
D: cd2 molecule (homo sapiens) (aka cd2 molecule)
E: leu-3 (homo sapiens) (aka cd4 molecule)
F: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
G: cd2 molecule (bos taurus) (aka cd2 molecule)
H: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
I: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
J: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
K: cd22 molecule (homo sapiens) (aka cd22 molecule)
L: bcm1 (homo sapiens) (aka cd48 molecule)
M: cd21 (homo sapiens) (aka complement c3d receptor 2)
N: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
O: lfa-2 (homo sapiens) (aka cd2 molecule)
P: None of the above. | [L; D; B] |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; ox45; blast-1]
<Options>: A: kit ligand (homo sapiens) (aka kit ligand)
B: bcm-1 (mus musculus) (aka cd48 antigen)
C: of45 (rattus norvegicus) (aka matrix extracellular phosphoglycoprotein)
D: vacuolar protein sorting 45 homolog (oryctolagus cuniculus) (aka vacuolar protein sorting 45 homolog)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
G: gpr45 (homo sapiens) (aka g protein-coupled receptor 45)
H: or4c45 (homo sapiens) (aka olfactory receptor family 4 subfamily c member 45 (gene/pseudogene))
I: gpr45 (oryctolagus cuniculus) (aka g protein-coupled receptor 45)
J: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
K: hcpeb-1 (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
L: bm-001 (homo sapiens) (aka cyclin l1)
M: blast (homo sapiens) (aka cd48 molecule)
N: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
O: blast-1 (mus musculus) (aka cd48 antigen)
P: None of the above. | [B; B; M] |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; ox45; blast-1]
<Options>: A: bcrm1 (homo sapiens) (aka sideroflexin 4)
B: kit ligand (homo sapiens) (aka kit ligand)
C: blast-2 (homo sapiens) (aka fc epsilon receptor ii)
D: gpr45 (rattus norvegicus) (aka g protein-coupled receptor 45)
E: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
F: blast (homo sapiens) (aka cd48 molecule)
G: hcpeb-1 (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
H: bcgf-1 (homo sapiens) (aka interleukin 4)
I: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
J: of45 (rattus norvegicus) (aka matrix extracellular phosphoglycoprotein)
K: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
L: vacuolar protein sorting 45 homolog (oryctolagus cuniculus) (aka vacuolar protein sorting 45 homolog)
M: g protein-coupled receptor 45 (oryctolagus cuniculus) (aka g protein-coupled receptor 45)
N: bcm-1 (mus musculus) (aka cd48 antigen)
O: olr45 (rattus norvegicus) (aka olfactory receptor family 52 subfamily k member 2)
P: None of the above. | [N; N; F] |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; ox45; blast-1]
<Options>: A: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
B: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
C: olr45 (rattus norvegicus) (aka olfactory receptor family 52 subfamily k member 2)
D: blast1 (homo sapiens) (aka cd48 molecule)
E: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
F: olfactory receptor family 4 subfamily c member 45 (gene/pseudogene) (homo sapiens) (aka olfactory receptor family 4 subfamily c member 45 (gene/pseudogene))
G: blast-2 (homo sapiens) (aka fc epsilon receptor ii)
H: hcpeb-1 (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
I: bcrm1 (homo sapiens) (aka sideroflexin 4)
J: g protein-coupled receptor 45 (oryctolagus cuniculus) (aka g protein-coupled receptor 45)
K: blast-1 (mus musculus) (aka cd48 antigen)
L: bcm-1 (mus musculus) (aka cd48 antigen)
M: kit ligand (homo sapiens) (aka kit ligand)
N: vacuolar protein sorting 45 homolog (oryctolagus cuniculus) (aka vacuolar protein sorting 45 homolog)
O: gpr45 (homo sapiens) (aka g protein-coupled receptor 45)
P: None of the above. | [L; L; D] |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [lfa3; cd2]
<Options>: A: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
B: cd22 molecule (homo sapiens) (aka cd22 molecule)
C: lfa-2 (homo sapiens) (aka cd2 molecule)
D: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
E: cd2 (homo sapiens) (aka cd2 molecule)
F: cd11a (homo sapiens) (aka integrin subunit alpha l)
G: lfa3 (homo sapiens) (aka cd58 molecule)
H: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
I: cd2 (gallus gallus) (aka cd2 molecule)
J: cd2 molecule (bos taurus) (aka cd2 molecule)
K: None of the above. | [G; E] |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [lfa3; cd2]
<Options>: A: cd21 (homo sapiens) (aka complement c3d receptor 2)
B: lfa-3 (homo sapiens) (aka cd58 molecule)
C: cd2 (bos taurus) (aka cd2 molecule)
D: cd228 (homo sapiens) (aka melanotransferrin)
E: cd11a (homo sapiens) (aka integrin subunit alpha l)
F: lfa-2 (homo sapiens) (aka cd2 molecule)
G: cd2 (homo sapiens) (aka cd2 molecule)
H: itga3 (homo sapiens) (aka integrin subunit alpha 3)
I: cd2 (gallus gallus) (aka cd2 molecule)
J: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
K: None of the above. | [B; G] |
<Instruct>: Given the context 'Mouse BCM1 is widely expressed on leukocytes and is likely to be anchored to the cell surface by a glycosyl-phosphatidylinositol anchor, as is the case for rat and human BCM1 antigen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1]
<Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
C: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
D: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
E: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
F: None of the above. | [A] |
<Instruct>: Given the context 'Mouse BCM1 is widely expressed on leukocytes and is likely to be anchored to the cell surface by a glycosyl-phosphatidylinositol anchor, as is the case for rat and human BCM1 antigen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1]
<Options>: A: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
B: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
C: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
D: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
E: None of the above. | [E] |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; bcm-1; atpa-3]
<Options>: A: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
B: atpaf1 (homo sapiens) (aka atp synthase mitochondrial f1 complex assembly factor 1)
C: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
D: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
E: atpa-3 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
F: atp3 (saccharomyces cerevisiae s288c) (aka f1f0 atp synthase subunit gamma)
G: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
H: atpap3 (arabidopsis thaliana) (aka purple acid phosphatase 3)
I: bcm-1 (mus musculus) (aka cd48 antigen)
J: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
K: bcm1 (homo sapiens) (aka cd48 molecule)
L: atp13a3 (homo sapiens) (aka atpase 13a3)
M: None of the above. | [I; I; E] |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; bcm-1; atpa-3]
<Options>: A: atp13a3 (homo sapiens) (aka atpase 13a3)
B: atp3 (saccharomyces cerevisiae s288c) (aka f1f0 atp synthase subunit gamma)
C: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
D: atppa3 (arabidopsis thaliana) (aka pyrophosphorylase 3)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
G: bcsc-1 (homo sapiens) (aka von willebrand factor a domain containing 5a)
H: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
I: bcm-1 (mus musculus) (aka cd48 antigen)
J: atpa-3 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
K: bcrm1 (homo sapiens) (aka sideroflexin 4)
L: atpap3 (arabidopsis thaliana) (aka purple acid phosphatase 3)
M: bcmp1 (homo sapiens) (aka transmembrane protein 47)
N: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
O: None of the above. | [I; I; J] |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; bcm-1; atpa-3]
<Options>: A: bcm-1 (mus musculus) (aka cd48 antigen)
B: atp1a3 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 3)
C: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
D: bcm1 (homo sapiens) (aka cd48 molecule)
E: bcrm1 (homo sapiens) (aka sideroflexin 4)
F: atpa-3 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
G: mb-1 (homo sapiens) (aka cd79a molecule)
H: atpap3 (arabidopsis thaliana) (aka purple acid phosphatase 3)
I: bcmp1 (homo sapiens) (aka transmembrane protein 47)
J: bcsc-1 (homo sapiens) (aka von willebrand factor a domain containing 5a)
K: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
L: atp synthase f1 subunit alpha pseudogene 3 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 3)
M: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
N: atp13a3 (xenopus tropicalis) (aka atpase type 13a3)
O: None of the above. | [A; A; F] |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; atp1a2]
<Options>: A: atp1a2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
B: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
C: atp1a2 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
D: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
E: atp6a2 (homo sapiens) (aka atpase h+ transporting v0 subunit a2)
F: atp2c1a (homo sapiens) (aka atpase secretory pathway ca2+ transporting 1)
G: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
H: atp1a2 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 2)
I: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
J: bcm1 (homo sapiens) (aka cd48 molecule)
K: None of the above. | [J; A] |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bcm1; atp1a2]
<Options>: A: atp6a2 (homo sapiens) (aka atpase h+ transporting v0 subunit a2)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: atpase na+/k+ transporting subunit alpha 2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
D: bcrm1 (homo sapiens) (aka sideroflexin 4)
E: atp1a2 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 2)
F: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
G: atp2a2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
H: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
I: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
J: atp2c1a (homo sapiens) (aka atpase secretory pathway ca2+ transporting 1)
K: None of the above. | [B; C] |
<Instruct>: Given the context 'A similar situation is seen in the region of the CD2 and LFA3 genes between mouse chromosome 3 and human chromosome 1p.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd2; lfa3]
<Options>: A: lfa3 (homo sapiens) (aka cd58 molecule)
B: cd21 (homo sapiens) (aka complement c3d receptor 2)
C: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
D: cd2 molecule (homo sapiens) (aka cd2 molecule)
E: cd2 (gallus gallus) (aka cd2 molecule)
F: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
G: itga3 (homo sapiens) (aka integrin subunit alpha 3)
H: cd11a (homo sapiens) (aka integrin subunit alpha l)
I: leu-3 (homo sapiens) (aka cd4 molecule)
J: cd228 (homo sapiens) (aka melanotransferrin)
K: None of the above. | [D; A] |
<Instruct>: Given the context 'A similar situation is seen in the region of the CD2 and LFA3 genes between mouse chromosome 3 and human chromosome 1p.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd2; lfa3]
<Options>: A: cd2 (homo sapiens) (aka cd2 molecule)
B: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
C: lfa-2 (homo sapiens) (aka cd2 molecule)
D: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
E: lfa3 (homo sapiens) (aka cd58 molecule)
F: cd2 molecule (bos taurus) (aka cd2 molecule)
G: cd21 (homo sapiens) (aka complement c3d receptor 2)
H: cd11a (homo sapiens) (aka integrin subunit alpha l)
I: cd228 (homo sapiens) (aka melanotransferrin)
J: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
K: None of the above. | [A; E] |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd2; lfa3; atpa-1; atp1a1]
<Options>: A: cd2 (homo sapiens) (aka cd2 molecule)
B: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
C: lfa-2 (homo sapiens) (aka cd2 molecule)
D: atp1a1os (homo sapiens) (aka atp1a1 antisense rna 1)
E: itga3 (homo sapiens) (aka integrin subunit alpha 3)
F: atp1a2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
G: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
H: lfa1a (homo sapiens) (aka integrin subunit alpha l)
I: atp6a (homo sapiens) (aka atpase h+/k+ transporting subunit alpha)
J: atpi (homo sapiens) (aka atp synthase inhibitory factor subunit 1)
K: atpa (escherichia coli str. k-12 substr. mg1655) (aka atp synthase f1 complex subunit alpha)
L: atpase na+/k+ transporting subunit alpha 1 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 1)
M: cd22 (homo sapiens) (aka cd22 molecule)
N: cd21 (homo sapiens) (aka complement c3d receptor 2)
O: lfa3 (homo sapiens) (aka cd58 molecule)
P: cd228 (homo sapiens) (aka melanotransferrin)
Q: atp synthase f1 subunit alpha (homo sapiens) (aka atp synthase f1 subunit alpha)
R: atp6n1a (homo sapiens) (aka atpase h+ transporting v0 subunit a1)
S: None of the above. | [A; O; S; L] |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [cd2; lfa3; atpa-1; atp1a1]
<Options>: A: lfa-3 (homo sapiens) (aka cd58 molecule)
B: atpiia (homo sapiens) (aka atpase phospholipid transporting 9a (putative))
C: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
D: cd2 molecule (bos taurus) (aka cd2 molecule)
E: atp6n1a (homo sapiens) (aka atpase h+ transporting v0 subunit a1)
F: atpase na+/k+ transporting subunit alpha 1 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 1)
G: cd22 molecule (homo sapiens) (aka cd22 molecule)
H: cd11a (homo sapiens) (aka integrin subunit alpha l)
I: atp1a3 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 3)
J: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
K: atp1a2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
L: cd2 (homo sapiens) (aka cd2 molecule)
M: atp6a (homo sapiens) (aka atpase h+/k+ transporting subunit alpha)
N: atp synthase f1 subunit alpha pseudogene 1 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 1)
O: atp1a1 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 1)
P: atp5a1 (homo sapiens) (aka atp synthase f1 subunit alpha)
Q: cd228 (homo sapiens) (aka melanotransferrin)
R: atpa (escherichia coli str. k-12 substr. mg1655) (aka atp synthase f1 complex subunit alpha)
S: lfa-2 (homo sapiens) (aka cd2 molecule)
T: cd2 (gallus gallus) (aka cd2 molecule)
U: None of the above. | [L; A; U; F] |
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