instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
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<Instruct>: Given the context 'Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmr1; fxr1; fxr2]
<Options>: A: fxr1-b (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
B: fxr2 (homo sapiens) (aka fmr1 autosomal homolog 2)
C: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
D: fxr (drosophila melanogaster) (fizzy-related (drosophila melanogaster)) (aka fizzy-related)
E: fmr1 (homo sapiens) (fragile site, folic acid type, rare, fra(x)(q27.3) a (homo sapiens)) (aka fragile site, folic acid type, rare, fra(x)(q27.3) a)
F: fmr1 autosomal homolog 1 (xenopus tropicalis) (xtfxr1p-a (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
G: nr1f2 (homo sapiens) (aka rar related orphan receptor b)
H: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
I: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
J: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
K: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
L: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
M: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
N: fxr1 (xenopus laevis) (aka fmr1 autosomal homolog 1 s homeolog)
O: None of the above. | [O; L; B] |
<Instruct>: Given the context 'Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmr1; fxr1; fxr2]
<Options>: A: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
B: fmr1 autosomal homolog 2 (homo sapiens) (aka fmr1 autosomal homolog 2)
C: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
D: fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)) (aka fragile x messenger ribonucleoprotein 1)
E: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
F: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
G: fxr1p (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
H: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
I: fmr1 (homo sapiens) (fragile site, folic acid type, rare, fra(x)(q27.3) a (homo sapiens)) (aka fragile site, folic acid type, rare, fra(x)(q27.3) a)
J: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
K: nr1f2 (homo sapiens) (aka rar related orphan receptor b)
L: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
M: None of the above. | [M; L; B] |
<Instruct>: Given the context 'Lack of expression of the fragile X mental retardation protein (FMRP) results in mental retardation and macroorchidism, seen as the major pathological symptoms in fragile X patients.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fragile x mental retardation protein; fmrp]
<Options>: A: fraxf (homo sapiens) (aka transmembrane protein 185a)
B: fmr1as (homo sapiens) (aka fmr1 antisense rna 1)
C: fmrp (homo sapiens) (aka fragile x messenger ribonucleoprotein 1)
D: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
E: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
F: fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)) (aka fragile x messenger ribonucleoprotein 1)
G: fmrp (mus musculus) (aka fragile x messenger ribonucleoprotein 1)
H: None of the above. | [C; C] |
<Instruct>: Given the context 'Lack of expression of the fragile X mental retardation protein (FMRP) results in mental retardation and macroorchidism, seen as the major pathological symptoms in fragile X patients.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fragile x mental retardation protein; fmrp]
<Options>: A: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
B: fraxf (homo sapiens) (aka transmembrane protein 185a)
C: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
D: fmrp (homo sapiens) (aka fragile x messenger ribonucleoprotein 1)
E: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
F: fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)) (aka fragile x messenger ribonucleoprotein 1)
G: fmr1as (homo sapiens) (aka fmr1 antisense rna 1)
H: fmr1 (homo sapiens) (fragile site, folic acid type, rare, fra(x)(q27.3) a (homo sapiens)) (aka fragile site, folic acid type, rare, fra(x)(q27.3) a)
I: fmrp (xenopus tropicalis) (aka fragile x messenger ribonucleoprotein 1)
J: None of the above. | [D; D] |
<Instruct>: Given the context 'Lack of expression of the fragile X mental retardation protein (FMRP) results in mental retardation and macroorchidism, seen as the major pathological symptoms in fragile X patients.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fragile x mental retardation protein; fmrp]
<Options>: A: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
B: fraxf (homo sapiens) (aka transmembrane protein 185a)
C: fmr1 (homo sapiens) (fragile site, folic acid type, rare, fra(x)(q27.3) a (homo sapiens)) (aka fragile site, folic acid type, rare, fra(x)(q27.3) a)
D: fmr1as (homo sapiens) (aka fmr1 antisense rna 1)
E: fmrp (xenopus tropicalis) (aka fragile x messenger ribonucleoprotein 1)
F: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
G: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
H: fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)) (aka fragile x messenger ribonucleoprotein 1)
I: None of the above. | [I; I] |
<Instruct>: Given the context 'FMRP is a cytoplasmic RNA-binding protein which cosediments with the 60S ribosomal subunit.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmrp]
<Options>: A: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
B: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
C: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
D: fragile x messenger ribonucleoprotein 1 (drosophila melanogaster) (aka fragile x messenger ribonucleoprotein 1)
E: fmrp (homo sapiens) (aka fragile x messenger ribonucleoprotein 1)
F: None of the above. | [E] |
<Instruct>: Given the context 'Recently, two proteins homologous to FMRP were discovered: FXR1 and FXR2.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmrp; fxr1; fxr2]
<Options>: A: fmrp (homo sapiens) (aka fragile x messenger ribonucleoprotein 1)
B: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
C: fxr2 (homo sapiens) (aka fmr1 autosomal homolog 2)
D: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
E: fxr (drosophila melanogaster) (fizzy-related (drosophila melanogaster)) (aka fizzy-related)
F: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
G: fxr1-b (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
H: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
I: fxr1p (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
J: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
K: fmrp (drosophila melanogaster) (aka fragile x messenger ribonucleoprotein 1)
L: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
M: fxr1 (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
N: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
O: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
P: None of the above. | [A; H; C] |
<Instruct>: Given the context 'Recently, two proteins homologous to FMRP were discovered: FXR1 and FXR2.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmrp; fxr1; fxr2]
<Options>: A: fmrp (homo sapiens) (aka fragile x messenger ribonucleoprotein 1)
B: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
C: fmrp (mus musculus) (aka fragile x messenger ribonucleoprotein 1)
D: fxr1-b (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
E: fxr1 (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
F: fmrp (xenopus tropicalis) (aka fragile x messenger ribonucleoprotein 1)
G: fmr1 autosomal homolog 2 (homo sapiens) (aka fmr1 autosomal homolog 2)
H: fxr1-b (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
I: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
J: fxr (drosophila melanogaster) (fizzy-related (drosophila melanogaster)) (aka fizzy-related)
K: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
L: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
M: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
N: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
O: None of the above. | [A; M; G] |
<Instruct>: Given the context 'Recently, two proteins homologous to FMRP were discovered: FXR1 and FXR2.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmrp; fxr1; fxr2]
<Options>: A: fmrp (xenopus tropicalis) (aka fragile x messenger ribonucleoprotein 1)
B: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
C: fmr1 autosomal homolog 2 (homo sapiens) (aka fmr1 autosomal homolog 2)
D: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
E: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
F: fmrp (homo sapiens) (aka fragile x messenger ribonucleoprotein 1)
G: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
H: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
I: fxr1 (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
J: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
K: fxr1-b (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
L: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
M: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
N: fxr1h (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
O: None of the above. | [F; L; C] |
<Instruct>: Given the context 'Recently, two proteins homologous to FMRP were discovered: FXR1 and FXR2.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmrp; fxr1; fxr2]
<Options>: A: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
B: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
C: fxr1h (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
D: fmr1 autosomal homolog 2 (homo sapiens) (aka fmr1 autosomal homolog 2)
E: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
F: fxr1-b (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
G: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
H: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
I: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
J: fxr1 (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
K: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
L: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
M: fmrp (xenopus tropicalis) (aka fragile x messenger ribonucleoprotein 1)
N: None of the above. | [N; E; D] |
<Instruct>: Given the context 'These novel proteins interact with FMRP and with each other and they are also associated with the 60S ribosomal subunit.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmrp]
<Options>: A: fmrp (mus musculus) (aka fragile x messenger ribonucleoprotein 1)
B: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
C: fragile x messenger ribonucleoprotein 1 (drosophila melanogaster) (aka fragile x messenger ribonucleoprotein 1)
D: fmrp (homo sapiens) (aka fragile x messenger ribonucleoprotein 1)
E: fmrp (xenopus tropicalis) (aka fragile x messenger ribonucleoprotein 1)
F: None of the above. | [D] |
<Instruct>: Given the context 'In adult brain, FMR1, FXR1 and FXR2 proteins are coexpressed in the cytoplasm of specific differentiated neurons only.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmr1; fxr1; fxr2]
<Options>: A: fxr1-b (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
B: fxr (drosophila melanogaster) (fizzy-related (drosophila melanogaster)) (aka fizzy-related)
C: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
D: fxr1h (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
E: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
F: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
G: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
H: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
I: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
J: fmr1 autosomal homolog 2 (homo sapiens) (aka fmr1 autosomal homolog 2)
K: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
L: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
M: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
N: fmr1 autosomal homolog 1 (xenopus tropicalis) (xtfxr1p-a (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
O: fxr1-b (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
P: None of the above. | [P; C; J] |
<Instruct>: Given the context 'In adult brain, FMR1, FXR1 and FXR2 proteins are coexpressed in the cytoplasm of specific differentiated neurons only.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmr1; fxr1; fxr2]
<Options>: A: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
B: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
C: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
D: fmr1 (drosophila melanogaster) (aka fragile x messenger ribonucleoprotein 1)
E: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
F: fxr1h (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
G: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
H: fmr1 autosomal homolog 1 (xenopus tropicalis) (xtfxr1p-a (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
I: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
J: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
K: fmr1 autosomal homolog 2 (homo sapiens) (aka fmr1 autosomal homolog 2)
L: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
M: None of the above. | [M; J; K] |
<Instruct>: Given the context 'In adult brain, FMR1, FXR1 and FXR2 proteins are coexpressed in the cytoplasm of specific differentiated neurons only.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmr1; fxr1; fxr2]
<Options>: A: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
B: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
C: fmr1 autosomal homolog 1 (xenopus tropicalis) (xtfxr1p-a (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
D: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
E: fxr (drosophila melanogaster) (fizzy-related (drosophila melanogaster)) (aka fizzy-related)
F: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
G: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
H: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
I: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
J: fxr1 (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
K: fxr2 (homo sapiens) (aka fmr1 autosomal homolog 2)
L: fxr1 (homo sapiens) (aka fmr1 autosomal homolog 1)
M: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
N: None of the above. | [N; L; K] |
<Instruct>: Given the context 'In adult brain, FMR1, FXR1 and FXR2 proteins are coexpressed in the cytoplasm of specific differentiated neurons only.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [fmr1; fxr1; fxr2]
<Options>: A: fmr1 autosomal homolog 1 (homo sapiens) (aka fmr1 autosomal homolog 1)
B: fxr2 (homo sapiens) (aka fmr1 autosomal homolog 2)
C: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 s homeolog)
D: fxr (xenopus tropicalis) (aka nuclear receptor subfamily 1 group h member 4)
E: fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 l homeolog (xenopus laevis)) (aka fmr1 autosomal homolog 1 l homeolog)
F: fxrb (homo sapiens) (aka nuclear receptor subfamily 1 group h member 5, pseudogene)
G: fmr1 autosomal homolog 1 (xenopus tropicalis) (xtfxr1p-a (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
H: fmr1 autosomal homolog 1 (mus musculus) (aka fmr1 autosomal homolog 1)
I: fmr1 autosomal homolog 1 (xenopus tropicalis) (frx1l (xenopus tropicalis)) (aka fmr1 autosomal homolog 1)
J: fxr (homo sapiens) (aka nuclear receptor subfamily 1 group h member 4)
K: fxr1 (xenopus tropicalis) (aka fmr1 autosomal homolog 1)
L: fxr (drosophila melanogaster) (fizzy-related (drosophila melanogaster)) (aka fizzy-related)
M: None of the above. | [M; M; B] |
<Instruct>: Given the context 'PHOG, a candidate gene for involvement in the short stature of Turner syndrome.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [phog]
<Options>: A: pho85 (saccharomyces cerevisiae s288c) (aka cyclin-dependent serine/threonine-protein kinase pho85)
B: phosphoglycolate phosphatase (homo sapiens) (aka phosphoglycolate phosphatase)
C: phog1 (homo sapiens) (aka shox homeobox)
D: phos (escherichia coli str. k-12 substr. mg1655) (aka phosphate abc transporter periplasmic binding protein)
E: pp2cg (homo sapiens) (aka protein phosphatase, mg2+/mn2+ dependent 1g)
F: None of the above. | [C] |
<Instruct>: Given the context 'We have named the gene PHOG, for pseudoautosomal homeobox-containing osteogenic gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [phog; pseudoautosomal homeobox-containing osteogenic gene]
<Options>: A: phop (escherichia coli str. k-12 substr. mg1655) (aka dna-binding transcriptional dual regulator phop)
B: phog1 (homo sapiens) (aka shox homeobox)
C: hptpg (homo sapiens) (aka protein tyrosine phosphatase receptor type g)
D: pho9 (saccharomyces cerevisiae s288c) (aka proteinase a)
E: sulfite oxidase pseudogene (homo sapiens) (aka sulfite oxidase pseudogene)
F: pp2cg (homo sapiens) (aka protein phosphatase, mg2+/mn2+ dependent 1g)
G: osteoglycin s homeolog (xenopus laevis) (aka osteoglycin s homeolog)
H: ooep-as (homo sapiens) (aka ooep antisense rna 1)
I: shox homeobox s homeolog (xenopus laevis) (aka shox homeobox s homeolog)
J: None of the above. | [B; B] |
<Instruct>: Given the context 'We have named the gene PHOG, for pseudoautosomal homeobox-containing osteogenic gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [phog; pseudoautosomal homeobox-containing osteogenic gene]
<Options>: A: osteoglycin s homeolog (xenopus laevis) (aka osteoglycin s homeolog)
B: phos (escherichia coli str. k-12 substr. mg1655) (aka phosphate abc transporter periplasmic binding protein)
C: shox homeobox s homeolog (xenopus laevis) (aka shox homeobox s homeolog)
D: hptpg (homo sapiens) (aka protein tyrosine phosphatase receptor type g)
E: phoh (escherichia coli str. k-12 substr. mg1655) (aka atp-binding protein phoh)
F: sulfite oxidase pseudogene (homo sapiens) (aka sulfite oxidase pseudogene)
G: phog1 (homo sapiens) (aka shox homeobox)
H: sebox homeobox (homo sapiens) (aka sebox homeobox)
I: pho9 (saccharomyces cerevisiae s288c) (aka proteinase a)
J: None of the above. | [G; G] |
<Instruct>: Given the context 'Its deletion in patients with short stature, the predicted altered dosage in 45,X individuals, along with the nature of the encoded protein and its expression pattern, make PHOG an attractive candidate for involvement in the short stature of Turner syndrome.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [phog]
<Options>: A: pho9 (saccharomyces cerevisiae s288c) (aka proteinase a)
B: phosphoglycolate phosphatase (homo sapiens) (aka phosphoglycolate phosphatase)
C: pho85 (saccharomyces cerevisiae s288c) (aka cyclin-dependent serine/threonine-protein kinase pho85)
D: pho88 (saccharomyces cerevisiae s288c) (aka snd3p)
E: phog1 (homo sapiens) (aka shox homeobox)
F: None of the above. | [E] |
<Instruct>: Given the context 'We have also found that the mouse homolog of PHOG is autosomal, which may help to explain the lack of a growth abnormality in mice with monosomy X.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [phog]
<Options>: A: phos (escherichia coli str. k-12 substr. mg1655) (aka phosphate abc transporter periplasmic binding protein)
B: phog1 (homo sapiens) (aka shox homeobox)
C: phoh (escherichia coli str. k-12 substr. mg1655) (aka atp-binding protein phoh)
D: pho85 (saccharomyces cerevisiae s288c) (aka cyclin-dependent serine/threonine-protein kinase pho85)
E: pho88 (saccharomyces cerevisiae s288c) (aka snd3p)
F: None of the above. | [B] |
<Instruct>: Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4; stat1]
<Options>: A: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
B: stat91 (homo sapiens) (aka signal transducer and activator of transcription 1)
C: stati4 (homo sapiens) (aka suppressor of cytokine signaling 6)
D: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
E: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
F: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
G: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
H: stat4 (bos taurus) (aka signal transducer and activator of transcription 4)
I: signal transducer and activator of transcription 2 (homo sapiens) (aka signal transducer and activator of transcription 2)
J: None of the above. | [F; B] |
<Instruct>: Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4; stat1]
<Options>: A: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
B: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
C: isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens)) (aka signal transducer and activator of transcription 1)
D: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
E: signal transducer and activator of transcription 2 (homo sapiens) (aka signal transducer and activator of transcription 2)
F: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
G: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
H: cis4 (homo sapiens) (aka suppressor of cytokine signaling 6)
I: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
J: None of the above. | [F; C] |
<Instruct>: Given the context 'STAT4 is phosphorylated following interleukin (IL)-12 stimulation and is essential for IL-12 signal transduction.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4]
<Options>: A: cis-4 (homo sapiens) (aka suppressor of cytokine signaling 6)
B: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
C: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
D: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
E: signal transducer and activator of transcription 4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
F: None of the above. | [D] |
<Instruct>: Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4; stat1]
<Options>: A: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
B: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
C: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
D: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
E: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
F: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
G: stat1 (homo sapiens) (aka signal transducer and activator of transcription 1)
H: signal transducer and activator of transcription 2 (homo sapiens) (aka signal transducer and activator of transcription 2)
I: stati4 (homo sapiens) (aka suppressor of cytokine signaling 6)
J: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
K: None of the above. | [J; G] |
<Instruct>: Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4; stat1]
<Options>: A: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
B: stat2 (homo sapiens) (aka signal transducer and activator of transcription 2)
C: isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens)) (aka signal transducer and activator of transcription 1)
D: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
E: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
F: stat4 (bos taurus) (aka signal transducer and activator of transcription 4)
G: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
H: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
I: stati4 (homo sapiens) (aka suppressor of cytokine signaling 6)
J: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
K: None of the above. | [E; C] |
<Instruct>: Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4; stat1]
<Options>: A: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
B: signal transducer and activator of transcription 2 (homo sapiens) (aka signal transducer and activator of transcription 2)
C: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
D: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
E: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
F: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
G: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
H: isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens)) (aka signal transducer and activator of transcription 1)
I: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
J: cis-4 (homo sapiens) (aka suppressor of cytokine signaling 6)
K: None of the above. | [C; H] |
<Instruct>: Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4; stat1]
<Options>: A: stat1 (homo sapiens) (aka signal transducer and activator of transcription 1)
B: signal transducer and activator of transcription 4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
C: stat4 (bos taurus) (aka signal transducer and activator of transcription 4)
D: cis-4 (homo sapiens) (aka suppressor of cytokine signaling 6)
E: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
F: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
G: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
H: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
I: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
J: None of the above. | [G; A] |
<Instruct>: Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat4; stat1]
<Options>: A: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
B: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
C: signal transducer and activator of transcription 4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
D: stat4 (bos taurus) (aka signal transducer and activator of transcription 4)
E: cis-4 (homo sapiens) (aka suppressor of cytokine signaling 6)
F: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
G: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
H: stat1 (homo sapiens) (aka signal transducer and activator of transcription 1)
I: None of the above. | [I; H] |
<Instruct>: Given the context 'However, human STAT1 is expressed ubiquitously, whereas human STAT4 is expressed in several tissues including spleen, heart, brain, peripheral blood cells, and testis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat1; stat4]
<Options>: A: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
B: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
C: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
D: cis4 (homo sapiens) (aka suppressor of cytokine signaling 6)
E: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
F: stat1 (homo sapiens) (aka signal transducer and activator of transcription 1)
G: signal transducer and activator of transcription 2 (homo sapiens) (aka signal transducer and activator of transcription 2)
H: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
I: stat4 (bos taurus) (aka signal transducer and activator of transcription 4)
J: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
K: None of the above. | [F; A] |
<Instruct>: Given the context 'However, human STAT1 is expressed ubiquitously, whereas human STAT4 is expressed in several tissues including spleen, heart, brain, peripheral blood cells, and testis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [stat1; stat4]
<Options>: A: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
B: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
C: signal transducer and activator of transcription 4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
D: cis-4 (homo sapiens) (aka suppressor of cytokine signaling 6)
E: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
F: isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens)) (aka signal transducer and activator of transcription 1)
G: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
H: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
I: signal transducer and activator of transcription 2 (homo sapiens) (aka signal transducer and activator of transcription 2)
J: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
K: None of the above. | [F; J] |
<Instruct>: Given the context 'Cloning and chromosome assignment to 1q32 of a human cDNA (RAB7L1) encoding a small GTP-binding protein, a member of the RAS superfamily.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rab7l1]
<Options>: A: rab7l (homo sapiens) (aka rab29, member ras oncogene family)
B: rab7l (xenopus tropicalis) (aka rab29, member ras oncogene family)
C: rab7, member ras oncogene family-like 1 (gallus gallus) (aka rab7, member ras oncogene family-like 1)
D: rab7b, member ras oncogene family l homeolog (xenopus laevis) (aka rab7b, member ras oncogene family l homeolog)
E: rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis)) (aka rab7a, member ras oncogene family l homeolog)
F: None of the above. | [A] |
<Instruct>: Given the context 'A full-length cDNA homologous to RAB7, a member of the RAB-related GTP-binding protein subfamily, was isolated from a human placenta cDNA library.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rab7]
<Options>: A: rab7 (drosophila melanogaster) (aka rab7)
B: rab7 (homo sapiens) (rab7a, member ras oncogene family (homo sapiens)) (aka rab7a, member ras oncogene family)
C: rab7l (homo sapiens) (aka rab29, member ras oncogene family)
D: rab7b (homo sapiens) (aka rab7b, member ras oncogene family)
E: rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis)) (aka rab7a, member ras oncogene family l homeolog)
F: None of the above. | [B] |
<Instruct>: Given the context 'This cDNA, designated RAB7L1, has an open reading frame of 609 nucleotides encoding 203 amino acids.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rab7l1]
<Options>: A: rab7l (xenopus laevis) (aka rab29, member ras oncogene family s homeolog)
B: rab7l (drosophila melanogaster) (aka rab32)
C: rab7l1 (homo sapiens) (aka rab29, member ras oncogene family)
D: rab7l (xenopus tropicalis) (aka rab29, member ras oncogene family)
E: rab7, member ras oncogene family-like 1 (gallus gallus) (aka rab7, member ras oncogene family-like 1)
F: None of the above. | [C] |
<Instruct>: Given the context 'In this work we provide a novel approach to this problem using a beta-arrestin2/green fluorescent protein conjugate (betaarr2-GFP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [beta-arrestin2; betaarr2]
<Options>: A: arrestin domain containing 2 (homo sapiens) (aka arrestin domain containing 2)
B: arrb2 (homo sapiens) (aka arrestin beta 2)
C: arrestin beta 2 (bos taurus) (aka arrestin beta 2)
D: arrestin, beta 2, pseudogene (rattus norvegicus) (aka arrestin, beta 2, pseudogene)
E: arr (drosophila melanogaster) (arrestin 2 (drosophila melanogaster)) (aka arrestin 2)
F: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
G: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
H: arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens)) (aka adrenoceptor beta 2)
I: None of the above. | [B; B] |
<Instruct>: Given the context 'In this work we provide a novel approach to this problem using a beta-arrestin2/green fluorescent protein conjugate (betaarr2-GFP).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [beta-arrestin2; betaarr2]
<Options>: A: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
B: arr2 (homo sapiens) (aka arrestin beta 2)
C: arrestin domain containing 2 (homo sapiens) (aka arrestin domain containing 2)
D: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
E: arrestin, beta 2, pseudogene (rattus norvegicus) (aka arrestin, beta 2, pseudogene)
F: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
G: arrestin beta 1 (homo sapiens) (aka arrestin beta 1)
H: arrestin 2 (drosophila melanogaster) (aka arrestin 2)
I: arrestin beta 2 (bos taurus) (aka arrestin beta 2)
J: None of the above. | [B; B] |
<Instruct>: Given the context 'Confocal microscopy demonstrates the translocation of betaarr2-GFP to more than 15 different ligand-activated GPCRs.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [betaarr2]
<Options>: A: arb2 (homo sapiens) (arrestin beta 2 (homo sapiens)) (aka arrestin beta 2)
B: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
C: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
D: arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens)) (aka adrenoceptor beta 2)
E: arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus)) (aka arrestin, beta 2, pseudogene)
F: None of the above. | [A] |
<Instruct>: Given the context 'The use of betaarr2-GFP as a biosensor to recognize the activation of pharmacologically distinct GPCRs should accelerate the identification of orphan receptors and permit the optical study of their signal transduction biology intractable to ordinary biochemical methods.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [betaarr2]
<Options>: A: arrestin beta 2 (homo sapiens) (aka arrestin beta 2)
B: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
C: arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus)) (aka arrestin, beta 2, pseudogene)
D: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
E: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
F: None of the above. | [A] |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatocyte growth factor activator inhibitor type 2; hepatocyte growth factor (hgf) activator; hgf]
<Options>: A: serine peptidase inhibitor kazal type 2 (homo sapiens) (aka serine peptidase inhibitor kazal type 2)
B: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
C: pai-2 (homo sapiens) (aka serpin family b member 2)
D: hgf activator (xenopus tropicalis) (aka hgf activator)
E: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
F: hgf5 (homo sapiens) (aka re1 silencing transcription factor)
G: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
H: serpin family i member 2 (homo sapiens) (aka serpin family i member 2)
I: hgf activator (homo sapiens) (aka hgf activator)
J: tissue factor pathway inhibitor 2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
K: hgfa (homo sapiens) (aka hgf activator)
L: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
M: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
N: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
O: None of the above. | [L; I; N] |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatocyte growth factor activator inhibitor type 2; hepatocyte growth factor (hgf) activator; hgf]
<Options>: A: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
B: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
C: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
D: pai2 (homo sapiens) (aka serpin family b member 2)
E: sf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
F: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
G: hgfa (homo sapiens) (aka hgf activator)
H: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
I: serine peptidase inhibitor kazal type 2 (homo sapiens) (aka serine peptidase inhibitor kazal type 2)
J: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
K: hgf5 (homo sapiens) (aka re1 silencing transcription factor)
L: serpin family i member 2 (homo sapiens) (aka serpin family i member 2)
M: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
N: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
O: None of the above. | [J; G; E] |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hepatocyte growth factor activator inhibitor type 2; hepatocyte growth factor (hgf) activator; hgf]
<Options>: A: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
B: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
C: hgfa (homo sapiens) (aka hgf activator)
D: hgfac (homo sapiens) (aka hgf activator)
E: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
F: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
G: pai-2 (homo sapiens) (aka serpin family b member 2)
H: serine peptidase inhibitor kazal type 2 (homo sapiens) (aka serine peptidase inhibitor kazal type 2)
I: serpina2 (homo sapiens) (aka serpin family a member 2 (gene/pseudogene))
J: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
K: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
L: hgf activator (xenopus tropicalis) (aka hgf activator)
M: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
N: None of the above. | [M; D; J] |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hgf activator; hgf activator inhibitor type 1; hai-1]
<Options>: A: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
B: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
C: hgf activator (rattus norvegicus) (aka hgf activator)
D: pai1 (homo sapiens) (aka serpin family e member 1)
E: hgf activator (sus scrofa) (aka hgf activator)
F: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
G: hgfa (homo sapiens) (aka hgf activator)
H: hypoxia inducible factor 1 subunit alpha inhibitor (homo sapiens) (aka hypoxia inducible factor 1 subunit alpha inhibitor)
I: haip1 (homo sapiens) (aka baculoviral iap repeat containing 3)
J: serine peptidase inhibitor, kunitz type 1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
K: agti (homo sapiens) (aka agouti signaling protein)
L: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
M: haik1 (homo sapiens) (aka keratin 23)
N: None of the above. | [G; J; J] |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hgf activator; hgf activator inhibitor type 1; hai-1]
<Options>: A: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
B: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
C: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
D: pai-1 (homo sapiens) (aka serpin family e member 1)
E: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
F: haip1 (homo sapiens) (aka baculoviral iap repeat containing 3)
G: hgfa (homo sapiens) (aka hgf activator)
H: serine peptidase inhibitor, kunitz type 1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
I: antizyme inhibitor 1 (homo sapiens) (aka antizyme inhibitor 1)
J: protein inhibitor of activated stat 1 (homo sapiens) (aka protein inhibitor of activated stat 1)
K: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
L: hgf activator (sus scrofa) (aka hgf activator)
M: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
N: hypoxia inducible factor 1 subunit alpha inhibitor (homo sapiens) (aka hypoxia inducible factor 1 subunit alpha inhibitor)
O: None of the above. | [G; H; H] |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hgf activator; hgf activator inhibitor type 1; hai-1]
<Options>: A: antizyme inhibitor 1 (homo sapiens) (aka antizyme inhibitor 1)
B: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
C: protein inhibitor of activated stat 1 (homo sapiens) (aka protein inhibitor of activated stat 1)
D: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
E: hgfac (homo sapiens) (aka hgf activator)
F: agti (homo sapiens) (aka agouti signaling protein)
G: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
H: haip1 (homo sapiens) (aka baculoviral iap repeat containing 3)
I: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
J: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
K: hgf activator (sus scrofa) (aka hgf activator)
L: hgf activator (rattus norvegicus) (aka hgf activator)
M: haik1 (homo sapiens) (aka keratin 23)
N: hypoxia inducible factor 1 subunit alpha inhibitor (homo sapiens) (aka hypoxia inducible factor 1 subunit alpha inhibitor)
O: None of the above. | [E; G; G] |
<Instruct>: Given the context 'HAI-1 is a novel member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-1]
<Options>: A: haik1 (homo sapiens) (aka keratin 23)
B: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
C: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
D: hait1 (homo sapiens) (aka solute carrier family 71 member 1)
E: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
F: None of the above. | [C] |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hgf activator; hai-2]
<Options>: A: hgfac (homo sapiens) (aka hgf activator)
B: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
C: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
D: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
E: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
F: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
G: inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
H: hgf activator (sus scrofa) (aka hgf activator)
I: serpinf2 (homo sapiens) (aka serpin family f member 2)
J: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
K: None of the above. | [A; C] |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hgf activator; hai-2]
<Options>: A: hgf activator (homo sapiens) (aka hgf activator)
B: hgf activator (rattus norvegicus) (aka hgf activator)
C: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
D: inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
E: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
F: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
G: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
H: serpinf2 (homo sapiens) (aka serpin family f member 2)
I: hgf activator (sus scrofa) (aka hgf activator)
J: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
K: None of the above. | [A; G] |
<Instruct>: Given the context 'The cDNA sequence revealed that HAI-2 is derived from a precursor protein of 252 amino acids and contains two Kunitz domains, indicating that HAI-2 is also a member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-2]
<Options>: A: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
B: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
C: inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
D: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
E: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
F: None of the above. | [D] |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-2; hai-1]
<Options>: A: inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
B: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
C: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
D: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
E: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
F: serpinf2 (homo sapiens) (aka serpin family f member 2)
G: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
H: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
I: haip1 (homo sapiens) (aka baculoviral iap repeat containing 3)
J: None of the above. | [H; B] |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-2; hai-1]
<Options>: A: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
B: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
C: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
D: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
E: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
F: haik1 (homo sapiens) (aka keratin 23)
G: iti-hc2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
H: haip1 (homo sapiens) (aka baculoviral iap repeat containing 3)
I: serpinf2 (homo sapiens) (aka serpin family f member 2)
J: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
K: None of the above. | [A; B] |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-2; hai-1; hgf activator; hgf]
<Options>: A: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
B: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
C: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
D: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
E: hgfac (homo sapiens) (aka hgf activator)
F: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
G: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
H: hgf activator (homo sapiens) (aka hgf activator)
I: hgf activator (rattus norvegicus) (aka hgf activator)
J: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
K: hait1 (homo sapiens) (aka solute carrier family 71 member 1)
L: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
M: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
N: hgf5 (homo sapiens) (aka re1 silencing transcription factor)
O: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
P: itih2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
Q: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
R: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
S: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
T: None of the above. | [G; M; E; L] |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-2; hai-1; hgf activator; hgf]
<Options>: A: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
B: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
C: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
D: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
E: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
F: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
G: hait1 (homo sapiens) (aka solute carrier family 71 member 1)
H: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
I: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
J: hgfa (homo sapiens) (aka hgf activator)
K: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
L: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
M: hgf activator (rattus norvegicus) (aka hgf activator)
N: serpinf2 (homo sapiens) (aka serpin family f member 2)
O: hgf activator (homo sapiens) (aka hgf activator)
P: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
Q: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
R: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
S: sf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
T: None of the above. | [D; B; J; S] |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-2; hai-1; hgf activator; hgf]
<Options>: A: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
B: serpinf2 (homo sapiens) (aka serpin family f member 2)
C: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
D: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
E: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
F: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
G: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
H: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
I: haik1 (homo sapiens) (aka keratin 23)
J: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
K: hgf activator (sus scrofa) (aka hgf activator)
L: hgf activator (rattus norvegicus) (aka hgf activator)
M: haip1 (homo sapiens) (aka baculoviral iap repeat containing 3)
N: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
O: sf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
P: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
Q: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
R: hgfa (homo sapiens) (aka hgf activator)
S: hgf activator (homo sapiens) (aka hgf activator)
T: None of the above. | [H; J; R; O] |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hai-2; hai-1; hgf activator; hgf]
<Options>: A: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
B: hgfac (homo sapiens) (aka hgf activator)
C: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
D: hgf activator (rattus norvegicus) (aka hgf activator)
E: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
F: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
G: hait1 (homo sapiens) (aka solute carrier family 71 member 1)
H: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
I: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
J: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
K: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
L: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
M: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
N: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
O: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
P: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
Q: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
R: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
S: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
T: serpinf2 (homo sapiens) (aka serpin family f member 2)
U: None of the above. | [Q; I; B; H] |
<Instruct>: Given the context 'Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2]
<Options>: A: glycogenin 2 (sus scrofa) (aka glycogenin 2)
B: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
C: glycogenin 2 (homo sapiens) (aka glycogenin 2)
D: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
E: glycogenin 1 (homo sapiens) (aka glycogenin 1)
F: None of the above. | [C] |
<Instruct>: Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2]
<Options>: A: glycogenin 2 (homo sapiens) (aka glycogenin 2)
B: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
C: gnb2 (homo sapiens) (aka g protein subunit beta 2)
D: gng2 (homo sapiens) (aka g protein subunit gamma 2)
E: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
F: glycogenin 2 (sus scrofa) (aka glycogenin 2)
G: glycogenin 1 (homo sapiens) (aka glycogenin 1)
H: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
I: glycogenin 2 (bos taurus) (aka glycogenin 2)
J: None of the above. | [A; A] |
<Instruct>: Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2]
<Options>: A: glycogenin 1 (homo sapiens) (aka glycogenin 1)
B: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
C: glycogenin 2 (sus scrofa) (aka glycogenin 2)
D: gng2 (homo sapiens) (aka g protein subunit gamma 2)
E: glycogenin 2 (bos taurus) (aka glycogenin 2)
F: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
G: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
H: gnb2 (homo sapiens) (aka g protein subunit beta 2)
I: None of the above. | [I; I] |
<Instruct>: Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2]
<Options>: A: gnl2 (homo sapiens) (aka g protein nucleolar 2)
B: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
C: glycogenin 2 (homo sapiens) (aka glycogenin 2)
D: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
E: glycogenin 2 (sus scrofa) (aka glycogenin 2)
F: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
G: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
H: gnb2 (homo sapiens) (aka g protein subunit beta 2)
I: glycogenin 2 (gallus gallus) (aka glycogenin 2)
J: None of the above. | [C; C] |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2alpha; gn-2beta; gn-2gamma]
<Options>: A: gng2 (homo sapiens) (aka g protein subunit gamma 2)
B: gnat2 (homo sapiens) (aka g protein subunit alpha transducin 2)
C: glycogenin 2 (homo sapiens) (aka glycogenin 2)
D: guanine nucleotide binding protein (g protein), gamma 2 (xenopus tropicalis) (aka guanine nucleotide binding protein (g protein), gamma 2)
E: gnai2 (homo sapiens) (aka g protein subunit alpha i2)
F: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
G: glycogenin 2 (sus scrofa) (aka glycogenin 2)
H: glycogenin 2 (gallus gallus) (aka glycogenin 2)
I: gnl2 (homo sapiens) (aka g protein nucleolar 2)
J: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
K: gnl3b (homo sapiens) (aka g protein nucleolar 3 like)
L: g protein nucleolar 2 (homo sapiens) (aka g protein nucleolar 2)
M: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
N: gng5b (homo sapiens) (aka g protein subunit gamma 5b)
O: None of the above. | [C; C; C; C] |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2alpha; gn-2beta; gn-2gamma]
<Options>: A: g protein subunit gamma 2 (homo sapiens) (aka g protein subunit gamma 2)
B: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
C: gng2 (homo sapiens) (aka g protein subunit gamma 2)
D: g protein subunit alpha transducin 2 (homo sapiens) (aka g protein subunit alpha transducin 2)
E: gnl2 (homo sapiens) (aka g protein nucleolar 2)
F: guanine nucleotide-binding protein subunit gamma 2-like (glycine max) (aka guanine nucleotide-binding protein subunit gamma 2-like)
G: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
H: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
I: g protein subunit gamma transducin 2 (homo sapiens) (aka g protein subunit gamma transducin 2)
J: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
K: glycogenin 2 (homo sapiens) (aka glycogenin 2)
L: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
M: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
N: gnai2 (homo sapiens) (aka g protein subunit alpha i2)
O: gng5b (homo sapiens) (aka g protein subunit gamma 5b)
P: gnb2 (homo sapiens) (aka g protein subunit beta 2)
Q: None of the above. | [K; K; K; K] |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2alpha; gn-2beta; gn-2gamma]
<Options>: A: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
B: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
C: gng5b (homo sapiens) (aka g protein subunit gamma 5b)
D: gnb2 (homo sapiens) (aka g protein subunit beta 2)
E: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
F: guanine nucleotide-binding protein subunit gamma 2-like (glycine max) (aka guanine nucleotide-binding protein subunit gamma 2-like)
G: gnai2 (homo sapiens) (aka g protein subunit alpha i2)
H: gnl2 (homo sapiens) (aka g protein nucleolar 2)
I: g protein subunit gamma 2 (homo sapiens) (aka g protein subunit gamma 2)
J: g protein subunit gamma transducin 2 (homo sapiens) (aka g protein subunit gamma transducin 2)
K: g protein subunit alpha transducin 2 (homo sapiens) (aka g protein subunit alpha transducin 2)
L: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
M: gng2 (homo sapiens) (aka g protein subunit gamma 2)
N: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
O: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
P: None of the above. | [P; P; P; P] |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2alpha; gn-2beta; gn-2gamma]
<Options>: A: glycogenin 2 (homo sapiens) (aka glycogenin 2)
B: guanine nucleotide binding protein (g protein), gamma 2 (xenopus tropicalis) (aka guanine nucleotide binding protein (g protein), gamma 2)
C: gnl2 (homo sapiens) (aka g protein nucleolar 2)
D: gnai2 (homo sapiens) (aka g protein subunit alpha i2)
E: glycogenin 2 (sus scrofa) (aka glycogenin 2)
F: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
G: gnat2 (homo sapiens) (aka g protein subunit alpha transducin 2)
H: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
I: gnb2 (homo sapiens) (aka g protein subunit beta 2)
J: glycogenin 2 (gallus gallus) (aka glycogenin 2)
K: g protein nucleolar 2 (homo sapiens) (aka g protein nucleolar 2)
L: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
M: gng5b (homo sapiens) (aka g protein subunit gamma 5b)
N: None of the above. | [A; A; A; A] |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [glycogenin-2; gn-2alpha; gn-2beta; gn-2gamma]
<Options>: A: glycogenin 2 (homo sapiens) (aka glycogenin 2)
B: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
C: guanine nucleotide binding protein (g protein), gamma 2 (xenopus tropicalis) (aka guanine nucleotide binding protein (g protein), gamma 2)
D: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
E: g protein subunit gamma transducin 2 (homo sapiens) (aka g protein subunit gamma transducin 2)
F: gng5b (homo sapiens) (aka g protein subunit gamma 5b)
G: gnai2 (homo sapiens) (aka g protein subunit alpha i2)
H: glycogen synthase 2 (homo sapiens) (aka glycogen synthase 2)
I: gnai2a (homo sapiens) (aka g protein subunit alpha i2 pseudogene 1)
J: gnat2 (homo sapiens) (aka g protein subunit alpha transducin 2)
K: gng2 (homo sapiens) (aka g protein subunit gamma 2)
L: glycogenin 2 (bos taurus) (aka glycogenin 2)
M: gnl2 (homo sapiens) (aka g protein nucleolar 2)
N: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
O: gnb2 (homo sapiens) (aka g protein subunit beta 2)
P: None of the above. | [A; A; A; A] |
<Instruct>: Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gn-2; muscle glycogenin]
<Options>: A: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
B: glycogenin 1 (homo sapiens) (aka glycogenin 1)
C: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
D: gn-2 (homo sapiens) (aka glycogenin 2)
E: gnb2 (homo sapiens) (aka g protein subunit beta 2)
F: brain glycogen phosphorylase (mus musculus) (aka brain glycogen phosphorylase)
G: liver glycogen phosphorylase (mus musculus) (aka liver glycogen phosphorylase)
H: glycogen synthase 1, muscle (mus musculus) (aka glycogen synthase 1, muscle)
I: gng2 (homo sapiens) (aka g protein subunit gamma 2)
J: glycogenin 1 (mus musculus) (aka glycogenin 1)
K: None of the above. | [D; B] |
<Instruct>: Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gn-2; muscle glycogenin]
<Options>: A: glycogenin 1 (homo sapiens) (aka glycogenin 1)
B: gng2 (homo sapiens) (aka g protein subunit gamma 2)
C: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
D: glycogen synthase 1, muscle (mus musculus) (aka glycogen synthase 1, muscle)
E: glycogenin 1 (mus musculus) (aka glycogenin 1)
F: liver glycogen phosphorylase (mus musculus) (aka liver glycogen phosphorylase)
G: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
H: brain glycogen phosphorylase (mus musculus) (aka brain glycogen phosphorylase)
I: gnb2 (homo sapiens) (aka g protein subunit beta 2)
J: None of the above. | [J; A] |
<Instruct>: Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gn-2; muscle glycogenin]
<Options>: A: glycogenin 2 (homo sapiens) (aka glycogenin 2)
B: gng2 (homo sapiens) (aka g protein subunit gamma 2)
C: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
D: liver glycogen phosphorylase (mus musculus) (aka liver glycogen phosphorylase)
E: glycogenin 1 (homo sapiens) (aka glycogenin 1)
F: muscle glycogen phosphorylase (mus musculus) (aka muscle glycogen phosphorylase)
G: glycogenin-1 (gallus gallus) (aka glycogenin 1)
H: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
I: gnl2 (homo sapiens) (aka g protein nucleolar 2)
J: gn2 (homo sapiens) (aka glycogenin 2)
K: None of the above. | [J; E] |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gn-2; skeletal muscle glycogen synthase]
<Options>: A: glycogen synthase 1 (xenopus tropicalis) (aka glycogen synthase 1)
B: gnb2 (homo sapiens) (aka g protein subunit beta 2)
C: gnl2 (homo sapiens) (aka g protein nucleolar 2)
D: glycogen synthase 1 (muscle) (gallus gallus) (aka glycogen synthase 1 (muscle))
E: gn-2 (homo sapiens) (aka glycogenin 2)
F: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
G: glycogen synthase 2 (mus musculus) (aka glycogen synthase 2)
H: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
I: glycogenin 1 (mus musculus) (aka glycogenin 1)
J: glycogen synthase 1 (homo sapiens) (aka glycogen synthase 1)
K: None of the above. | [E; J] |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gn-2; skeletal muscle glycogen synthase]
<Options>: A: gn-2 (homo sapiens) (aka glycogenin 2)
B: gng2 (homo sapiens) (aka g protein subunit gamma 2)
C: gnb2 (homo sapiens) (aka g protein subunit beta 2)
D: glycogen synthase 2 (homo sapiens) (aka glycogen synthase 2)
E: glycogen synthase 1 (muscle) (gallus gallus) (aka glycogen synthase 1 (muscle))
F: muscle glycogen phosphorylase (mus musculus) (aka muscle glycogen phosphorylase)
G: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
H: glycogenin 1 (mus musculus) (aka glycogenin 1)
I: gnl2 (homo sapiens) (aka g protein nucleolar 2)
J: glycogen synthase 1 (homo sapiens) (aka glycogen synthase 1)
K: None of the above. | [A; J] |
<Instruct>: Given the context 'Antibodies raised against GN-2 produced in E. coli recognized proteins of Mr approximately 66,000 present in extracts of rat liver and in cultured H4IIEC3 hepatoma cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gn-2]
<Options>: A: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
B: g protein nucleolar 2 (homo sapiens) (aka g protein nucleolar 2)
C: gnb2 (homo sapiens) (aka g protein subunit beta 2)
D: gn-2 (homo sapiens) (aka glycogenin 2)
E: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
F: None of the above. | [D] |
<Instruct>: Given the context 'In H4IIEC3 cells, most of the GN-2 was present as a free protein but some was covalently associated with glycogen fractions and was only released by treatment with alpha-amylase.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gn-2]
<Options>: A: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
B: gnb2 (homo sapiens) (aka g protein subunit beta 2)
C: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
D: gn2 (homo sapiens) (aka glycogenin 2)
E: g protein nucleolar 2 (homo sapiens) (aka g protein nucleolar 2)
F: None of the above. | [D] |
<Instruct>: Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [muscle form of glycogenin; glycogenin-1]
<Options>: A: glycogen synthase 1, muscle (mus musculus) (aka glycogen synthase 1, muscle)
B: liver glycogen phosphorylase (mus musculus) (aka liver glycogen phosphorylase)
C: brain glycogen phosphorylase (mus musculus) (aka brain glycogen phosphorylase)
D: glycogen phosphorylase 1 (glycine max) (aka glycogen phosphorylase 1)
E: glycogenin-1 (caenorhabditis elegans) (aka glycogenin-1)
F: glycogenin 1 (homo sapiens) (aka glycogenin 1)
G: glycogenin 1 (xenopus tropicalis) (aka glycogenin 1)
H: glycogen synthase 1 (homo sapiens) (aka glycogen synthase 1)
I: None of the above. | [F; F] |
<Instruct>: Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [muscle form of glycogenin; glycogenin-1]
<Options>: A: glycogen phosphorylase 1 (glycine max) (aka glycogen phosphorylase 1)
B: glycogenin-1 (caenorhabditis elegans) (aka glycogenin-1)
C: glycogen synthase 1, muscle (mus musculus) (aka glycogen synthase 1, muscle)
D: glycogenin 1 (xenopus tropicalis) (aka glycogenin 1)
E: liver glycogen phosphorylase (mus musculus) (aka liver glycogen phosphorylase)
F: brain glycogen phosphorylase (mus musculus) (aka brain glycogen phosphorylase)
G: glycogen synthase 1 (homo sapiens) (aka glycogen synthase 1)
H: None of the above. | [H; H] |
<Instruct>: Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [muscle form of glycogenin; glycogenin-1]
<Options>: A: glycogenin 1 (mus musculus) (aka glycogenin 1)
B: glycogenin-1 (caenorhabditis elegans) (aka glycogenin-1)
C: glycogen synthase 1, muscle (mus musculus) (aka glycogen synthase 1, muscle)
D: glycogenin 2 (homo sapiens) (aka glycogenin 2)
E: glycogenin 1 (homo sapiens) (aka glycogenin 1)
F: glycogen synthase 1 (homo sapiens) (aka glycogen synthase 1)
G: None of the above. | [E; E] |
<Instruct>: Given the context 'hSK4, a member of a novel subfamily of calcium-activated potassium channels.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hsk4]
<Options>: A: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
B: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
C: huk4 (homo sapiens) (aka phospholipase d family member 3)
D: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
E: map4k4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 4)
F: None of the above. | [B] |
<Instruct>: Given the context 'The gene for hSK4, a novel human small conductance calcium-activated potassium channel, or SK channel, has been identified and expressed in Chinese hamster ovary cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hsk4]
<Options>: A: huk4 (homo sapiens) (aka phospholipase d family member 3)
B: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
C: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
D: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
E: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
F: None of the above. | [D] |
<Instruct>: Given the context 'In physiological saline hSK4 generates a conductance of approximately 12 pS, a value in close agreement with that of other cloned SK channels.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hsk4]
<Options>: A: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
B: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
C: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
D: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
E: serine/threonine kinase 4 (homo sapiens) (aka serine/threonine kinase 4)
F: None of the above. | [D] |
<Instruct>: Given the context 'Like other members of this family, the polypeptide encoded by hSK4 contains a previously unnoted leucine zipper-like domain in its C terminus of unknown function.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hsk4]
<Options>: A: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
B: map4k4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 4)
C: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
D: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
E: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
F: None of the above. | [E] |
<Instruct>: Given the context 'hSK4 appears unique, however, in its very high affinity for Ca2+ (EC50 of 95 nM) and its predominant expression in nonexcitable tissues of adult animals.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hsk4]
<Options>: A: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
B: huk4 (homo sapiens) (aka phospholipase d family member 3)
C: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
D: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
E: serine/threonine kinase 4 (homo sapiens) (aka serine/threonine kinase 4)
F: None of the above. | [D] |
<Instruct>: Given the context 'Together with the relatively low homology of hSK4 to other SK channel polypeptides (approximately 40% identical), these data suggest that hSK4 belongs to a novel subfamily of SK channels.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hsk4]
<Options>: A: map4k4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 4)
B: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
C: huk4 (homo sapiens) (aka phospholipase d family member 3)
D: stk4 (homo sapiens) (aka serine/threonine kinase 4)
E: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
F: None of the above. | [E] |
<Instruct>: Given the context 'Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gm-csf/il-3/il-5 receptor common beta chain]
<Options>: A: colony stimulating factor 2 receptor subunit beta (bos taurus) (aka colony stimulating factor 2 receptor subunit beta)
B: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: csf2rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
D: colony stimulating factor 2 receptor subunit beta (sus scrofa) (aka colony stimulating factor 2 receptor subunit beta)
E: il5r (homo sapiens) (aka interleukin 5 receptor subunit alpha)
F: None of the above. | [C] |
<Instruct>: Given the context 'In some cases congenital PAP is associated with hereditary surfactant protein (SP)-B deficiency.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [surfactant protein (sp)-b]
<Options>: A: surfactant protein b (bos taurus) (aka surfactant protein b)
B: surfactant protein b (sus scrofa) (aka surfactant protein b)
C: sp-b (homo sapiens) (aka surfactant protein b)
D: sftp1b (homo sapiens) (surfactant protein a1 (homo sapiens)) (aka surfactant protein a1)
E: sftp1b (homo sapiens) (surfactant protein a2 (homo sapiens)) (aka surfactant protein a2)
F: None of the above. | [C] |
<Instruct>: Given the context 'In some cases congenital PAP is associated with hereditary surfactant protein (SP)-B deficiency.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [surfactant protein (sp)-b]
<Options>: A: sftp1b (homo sapiens) (surfactant protein a2 (homo sapiens)) (aka surfactant protein a2)
B: surfactant protein b (bos taurus) (aka surfactant protein b)
C: sftp1b (homo sapiens) (surfactant protein a1 (homo sapiens)) (aka surfactant protein a1)
D: surfactant protein b (sus scrofa) (aka surfactant protein b)
E: None of the above. | [E] |
<Instruct>: Given the context 'In mice, PAP has been generated by targeted deletion of the genes for either the GM-CSF/IL-3/IL-5 receptor common beta chain (beta c) or GM-CSF.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gm-csf/il-3/il-5 receptor common beta chain; beta c]
<Options>: A: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
B: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
C: betan (homo sapiens) (aka dna polymerase lambda)
D: colony stimulating factor 2 receptor subunit beta (sus scrofa) (aka colony stimulating factor 2 receptor subunit beta)
E: il3rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
F: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
G: betacellulin (homo sapiens) (aka betacellulin)
H: beta3b (homo sapiens) (aka basic helix-loop-helix family member e23)
I: colony stimulating factor 2 receptor subunit beta (bos taurus) (aka colony stimulating factor 2 receptor subunit beta)
J: il5r (homo sapiens) (aka interleukin 5 receptor subunit alpha)
K: None of the above. | [E; E] |
<Instruct>: Given the context 'In mice, PAP has been generated by targeted deletion of the genes for either the GM-CSF/IL-3/IL-5 receptor common beta chain (beta c) or GM-CSF.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [gm-csf/il-3/il-5 receptor common beta chain; beta c]
<Options>: A: colony stimulating factor 2 receptor subunit beta (bos taurus) (aka colony stimulating factor 2 receptor subunit beta)
B: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
E: betan (homo sapiens) (aka dna polymerase lambda)
F: il3rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
G: beta3b (homo sapiens) (aka basic helix-loop-helix family member e23)
H: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
I: colony stimulating factor 3 receptor (homo sapiens) (aka colony stimulating factor 3 receptor)
J: il5r (homo sapiens) (aka interleukin 5 receptor subunit alpha)
K: None of the above. | [F; F] |
<Instruct>: Given the context 'Here, we describe an expression defect of beta c in three of seven pediatric patients with PAP and in one patient with severe lung disease suspected to be PAP.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [beta c]
<Options>: A: betan (homo sapiens) (aka dna polymerase lambda)
B: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
C: betacellulin (homo sapiens) (aka betacellulin)
D: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
E: propionyl-coa carboxylase subunit beta (homo sapiens) (aka propionyl-coa carboxylase subunit beta)
F: None of the above. | [F] |
<Instruct>: Given the context 'The patients failed to express normal levels of beta c as shown by flow cytometry.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [beta c]
<Options>: A: betacellulin (homo sapiens) (aka betacellulin)
B: beta3b (homo sapiens) (aka basic helix-loop-helix family member e23)
C: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
D: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
E: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
F: None of the above. | [F] |
<Instruct>: Given the context 'Strikingly reduced or absent function of beta c was demonstrated by ligand binding studies and progenitor clonogenic assays.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [beta c]
<Options>: A: casein beta (homo sapiens) (aka casein beta)
B: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
C: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
D: betacellulin (homo sapiens) (aka betacellulin)
E: betan (homo sapiens) (aka dna polymerase lambda)
F: None of the above. | [F] |
<Instruct>: Given the context 'Analysis of beta c DNA revealed a point mutation from proline to threonine at codon 602 in one patient.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [beta c]
<Options>: A: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
B: betan (homo sapiens) (aka dna polymerase lambda)
C: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
D: betacellulin (homo sapiens) (aka betacellulin)
E: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
F: None of the above. | [F] |
<Instruct>: Given the context 'Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [quinolinate phosphoribosyltransferase]
<Options>: A: quinolinate phosphoribosyltransferase (gallus gallus) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (bos taurus) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
E: quinolinate phosphoribosyltransferase (mus musculus) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | [C] |
<Instruct>: Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [quinolinate phosphoribosyltransferase; qprtase]
<Options>: A: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (bos taurus) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
D: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
E: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
F: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
G: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
H: quinolinate phosphoribosyltransferase (gallus gallus) (aka quinolinate phosphoribosyltransferase)
I: None of the above. | [C; C] |
<Instruct>: Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [quinolinate phosphoribosyltransferase; qprtase]
<Options>: A: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
B: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
C: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (rattus norvegicus) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
F: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
G: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
H: quinolinate phosphoribosyltransferase (bos taurus) (aka quinolinate phosphoribosyltransferase)
I: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
J: None of the above. | [I; I] |
<Instruct>: Given the context 'As the first step to elucidate molecular basis underlying the quinolinate metabolism, the cDNA encoding human brain QPRTase was cloned and characterized.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [qprtase]
<Options>: A: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
C: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
D: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
E: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | [E] |
<Instruct>: Given the context 'Utilizing partial amino acid sequences obtained from highly purified porcine kidney QPRTase, a human isolog was obtained from a human brain cDNA library.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [qprtase]
<Options>: A: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
B: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
C: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
E: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
F: None of the above. | [C] |
<Instruct>: Given the context 'To confirm that the cDNA clone encodes human QPRTase, its functional expression was studied in a bacterial host.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [qprtase]
<Options>: A: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
C: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
D: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
E: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | [E] |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [qprtase; nadc]
<Options>: A: qprt (homo sapiens) (aka quinolinate phosphoribosyltransferase)
B: nadc1 (rattus norvegicus) (aka solute carrier family 13 member 2)
C: nedscac (homo sapiens) (aka mediator complex subunit 27)
D: nadc1 (homo sapiens) (aka solute carrier family 13 member 2)
E: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
F: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
G: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
H: nadc3 (homo sapiens) (aka solute carrier family 13 member 3)
I: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
J: None of the above. | [I; I] |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [qprtase; nadc]
<Options>: A: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
B: nedscac (homo sapiens) (aka mediator complex subunit 27)
C: nadc-1 (oryctolagus cuniculus) (aka solute carrier family 13 member 2)
D: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
F: nadc3 (homo sapiens) (aka solute carrier family 13 member 3)
G: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
H: nadc1 (rattus norvegicus) (aka solute carrier family 13 member 2)
I: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
J: None of the above. | [I; I] |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [qprtase; nadc]
<Options>: A: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
B: nadc3 (homo sapiens) (aka solute carrier family 13 member 3)
C: nadc-1 (oryctolagus cuniculus) (aka solute carrier family 13 member 2)
D: nedscac (homo sapiens) (aka mediator complex subunit 27)
E: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
F: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
G: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
H: nadc1 (rattus norvegicus) (aka solute carrier family 13 member 2)
I: None of the above. | [I; I] |
<Instruct>: Given the context 'It is concluded that the cloned cDNA encodes human QPRTase which is functional beyond the phylogenic boundary.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [qprtase]
<Options>: A: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
B: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
D: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
E: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | [E] |
<Instruct>: Given the context 'Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tm4sf5]
<Options>: A: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
B: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
C: tm4sf6 (homo sapiens) (aka tetraspanin 6)
D: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
E: tm4sf4 (homo sapiens) (aka transmembrane 4 l six family member 4)
F: None of the above. | [B] |
<Instruct>: Given the context 'In a previous large-scale screening for differentially expressed genes in pancreatic cancer, a gene was identified that was highly overexpressed in pancreatic cancer encoding a novel putative tetraspan transmembrane protein highly homologous to the tumour-associated antigen L6.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tumour-associated antigen l6]
<Options>: A: l6 (homo sapiens) (ribosomal protein l6 (homo sapiens)) (aka ribosomal protein l6)
B: paraneoplastic antigen-like protein 6a (homo sapiens) (aka paraneoplastic antigen-like protein 6a)
C: cancer/testis antigen family 47 member a6 (homo sapiens) (aka cancer/testis antigen family 47 member a6)
D: l6 (homo sapiens) (transmembrane 4 l six family member 1 (homo sapiens)) (aka transmembrane 4 l six family member 1)
E: rpl7ap6 (homo sapiens) (aka ribosomal protein l7a pseudogene 6)
F: None of the above. | [D] |
<Instruct>: Given the context 'Using a radiation hybrid panel the identified human gene named TM4SF5 (transmembrane 4 superfamily member 5) was localized to chromosome 17 in the region 17p13.3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [tm4sf5; transmembrane 4 superfamily member 5]
<Options>: A: transmembrane 4 l six family member 5 (sus scrofa) (aka transmembrane 4 l six family member 5)
B: tm4sf3 (homo sapiens) (aka tetraspanin 8)
C: tm4sf (homo sapiens) (aka tetraspanin 1)
D: tetraspanin 5 (homo sapiens) (aka tetraspanin 5)
E: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
F: tm4-a (homo sapiens) (aka tetraspanin 3)
G: tm4sf10 (homo sapiens) (aka transmembrane protein 47)
H: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
I: tetraspanin 4 (homo sapiens) (aka tetraspanin 4)
J: None of the above. | [E; E] |
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