instruction stringlengths 225 2.35k | input stringlengths 89 1.5k | response stringclasses 698
values |
|---|---|---|
<Instruct>: Given the context 'In an effort to clarify the association of BD with antibody to kinectin, it is essential to measure antibody to kinectin in larger patient populations including both BD, probable BD and important autoimmune rheumatic diseases such as SLE, SjS, rheumatoid arthritis etc., as well as those d... | <Mentions>: [patient]
<Options>: A: subsection
B: kingdom
C: suborder
D: homo sapiens (human) (aka homo sapiens)
E: theraps
F: None of the above. | [D] |
<Instruct>: Given the context 'A novel DNA-binding protein modulating methicillin resistance in Staphylococcus aureus
Abstract
Background
Methicillin resistance in Staphylococcus aureus is conferred by the mecA-encoded penicillin-binding protein PBP2a.', select the correct biomedical concept for each mention using the ... | <Mentions>: [staphylococcus aureus]
<Options>: A: aurococcus (aka staphylococcus)
B: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
C: staphylococcus pyogenes aureus (aka staphylococcus aureus)
D: staphylococcus aureus pa (staphylococcus aureus strain p... | [C] |
<Instruct>: Given the context 'A novel DNA-binding protein modulating methicillin resistance in Staphylococcus aureus
Abstract
Background
Methicillin resistance in Staphylococcus aureus is conferred by the mecA-encoded penicillin-binding protein PBP2a.', select the correct biomedical concept for each mention using the ... | <Mentions>: [staphylococcus aureus]
<Options>: A: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
C: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staph... | [E] |
<Instruct>: Given the context 'Nonpolar deletion of SA1665, in heterogeneously methicillin resistant S. aureus (MRSA) of different genetic backgrounds, increased methicillin resistance levels in a strain dependent manner.', select the correct biomedical concept for each mention using the provided options. Answer by lis... | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus group (aka staphylococcaceae)
C: micrococcus aureus (aka staphylococcus aureus)
D: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. a... | [C; C] |
<Instruct>: Given the context 'Nonpolar deletion of SA1665, in heterogeneously methicillin resistant S. aureus (MRSA) of different genetic backgrounds, increased methicillin resistance levels in a strain dependent manner.', select the correct biomedical concept for each mention using the provided options. Answer by lis... | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
B: staphylococcus aureus m2
C: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
D: staphylococcus aureus pa (staphyloco... | [A; A] |
<Instruct>: Given the context 'Conclusion
SA1665 is a new chromosomal factor which influences methicillin resistance in MRSA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus str. mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
C: staphylococcus aureus (staphyloco... | [C] |
<Instruct>: Given the context 'Background
Methicillin resistant S. aureus (MRSA) are an ever increasing threat, both in clinical settings and more recently as an emerging community acquired pathogen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opti... | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus sp. s
B: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
C: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
D: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphyloc... | [C; C] |
<Instruct>: Given the context 'Background
Methicillin resistant S. aureus (MRSA) are an ever increasing threat, both in clinical settings and more recently as an emerging community acquired pathogen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected opti... | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus aureus m1
B: staphylococcus simulans staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
C: 'staphylococcus faecalis' (aka staphylococcus faecalis)
D: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
E: micrococcus epidermid... | [F; F] |
<Instruct>: Given the context 'In S. aureus, methicillin resistance is conferred by an acquired, β-lactam-insensitive penicillin-binding protein (PBP), PBP2a', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [s. aureus]
<Options>: A: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus sp. s
C: micrococcus epidermidis (aka staphylococcus epidermidis)
D: micrococcus pyogenes (aka staphylococcus aureus)
E: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans st... | [D] |
<Instruct>: Given the context 'In S. aureus, methicillin resistance is conferred by an acquired, β-lactam-insensitive penicillin-binding protein (PBP), PBP2a', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [s. aureus]
<Options>: A: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
B: staphylococcus sp. s
C: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
D: micrococcus epidermidis (aka staphylococcus ... | [E] |
<Instruct>: Given the context 'Heterogeneously resistant MRSA, when exposed to β-lactam antibiotics, segregate highly resistant subpopulations, which are much more resistant than the majority of the cells [10].', select the correct biomedical concept for each mention using the provided options. Answer by listing the se... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus aureus m1
C: staphylococcus aureus subsp. aureus strain usa300 (aka staphylococcus aureus subsp. aureus usa300)
D: staphylococcus simulans bv. staphylolyti... | [E] |
<Instruct>: Given the context 'The vast MIC differences between MRSA strains, the population heterogeneity within single strains and the dependence of resistance levels on external factors are reflected in these many structural genes and global regulators, which can influence resistance levels.
', select the correct bi... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus m1
C: staphylococcus aureus m2
D: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus sub... | [E] |
<Instruct>: Given the context 'While typically considered nosocomial pathogens, new faster growing and apparently more virulent MRSA have begun spreading in the community.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, s... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
B: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
C: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylo... | [E] |
<Instruct>: Given the context 'Interestingly, these emerging strains often express very low methicillin resistance, e.g. the MRSA clone spreading amongst intravenous drug users in the Zurich area, which has an in vitro doubling time of 25 min, but oxacillin MICs of only 0.5 to 4 μg/ml', select the correct biomedical co... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
B: staphylococcus aureus m1
C: staphylococcus aureus m2
D: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus au... | [E] |
<Instruct>: Given the context 'To identify potential factors involved in mecA regulation or methicillin resistance levels in such an extremely low level resistant MRSA, we performed DNA-binding protein purification assays, using the mecA operator region as bait.', select the correct biomedical concept for each mention ... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus m2
B: staphylococcus aureus m1
C: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
D: micrococcus aureus (aka staphylococcus aureus)
E: staphylococcus aureus pa (staph... | [D] |
<Instruct>: Given the context 'Results
Identification of SA1665
MRSA strain CHE482 is the type strain for the so-called "drug clone" spreading amongst intravenous drug users in the Zurich area', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, on... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
B: staphylococcus staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
C: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
D: micrococcu... | [D] |
<Instruct>: Given the context 'However, like most other low-level resistant MRSA, it can segregate a small proportion of higher resistant subclones in the presence of β-lactams.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each ment... | <Mentions>: [mrsa]
<Options>: A: staphylococcus pyogenes aureus (aka staphylococcus aureus)
B: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
C: staphylococcus aureus m1
D: staphylococcus staphylolyticus (aka staphylococcus... | [A] |
<Instruct>: Given the context 'We hypothesized that regulation of methicillin resistance in such low-level resistant clonal lineages may differ qualitatively from classical heterogeneously- or highly-resistant MRSA.
', select the correct biomedical concept for each mention using the provided options. Answer by listing ... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
B: staphylococcus aureus m1
C: staphylococcus aureus subsp. aureus mrsa_pr1 (staphylococcus aureus subsp. aureus strain mrsa_pr1) (aka staphylo... | [E] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept ... | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: staphylococcus saccharolyticus (peptococcus saccharolyticus) (aka staphylococcus saccharolyticus)
B: staphylococcus haemolyticus
C: staphylococcus saprophyticus (staphylococcus saprophyticus subsp. bovis) (aka staphylococcus saprop... | [J; B; F; C] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept ... | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: streptococcus gallolyticus (streptococcus gallolyticus osawa et al. 1996) (aka streptococcus gallolyticus)
B: streptobacterium casei (aka lacticaseibacillus casei)
C: staphylococcus hominis subsp. hominis
D: staphylococcus epidermi... | [N; O; T; E] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept ... | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
B: streptobacterium casei (aka lacticaseibacillus casei)
C: staphylococcus pyogenes aureus (aka staphylococcus aureus)
D: chromobacterium hae... | [C; P; L; G] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept ... | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: 'staphylococcus faecalis' (aka staphylococcus faecalis)
B: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
C: streptobacterium casei (aka lacticaseibacillus casei)
D: staphylococcus pyogenes aureus (aka stap... | [D; I; E; T] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept ... | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: staphylococcus aureus subsp. anaerobius (aka staphylococcus aureus)
B: micrococcus aureus (aka staphylococcus aureus)
C: staphylococcus hominis
D: staphylococcus group (aka staphylococcaceae)
E: brachybacterium epidermidis
F: bacil... | [A; H; O; G] |
<Instruct>: Given the context 'Conversely, there were no orfs highly similar to SA1665 found in other bacterial species, with the most similar sequences found in Bacillus licheniformis DSM13 and Desulfitobacterium hafniense Y51, which shared only 64% and 59% similarity, respectively.
', select the correct biomedical c... | <Mentions>: [bacillus licheniformis; desulfitobacterium hafniense y51]
<Options>: A: desulfococcus sp. dsm 8541
B: bacillus amylosacchariticus (aka bacillus subtilis subsp. amylosacchariticus)
C: bacillus natto (aka bacillus subtilis)
D: bacillus licheniformis 5-2-d (bacillus licheniformis strain 5-2-d) (aka bacillus l... | [I; J] |
<Instruct>: Given the context 'Conversely, there were no orfs highly similar to SA1665 found in other bacterial species, with the most similar sequences found in Bacillus licheniformis DSM13 and Desulfitobacterium hafniense Y51, which shared only 64% and 59% similarity, respectively.
', select the correct biomedical c... | <Mentions>: [bacillus licheniformis; desulfitobacterium hafniense y51]
<Options>: A: desulfitobacterium dehalogenans dsm 9161 (aka desulfitobacterium dehalogenans atcc 51507)
B: desulfitobacterium hafniense strain y51 (aka desulfitobacterium hafniense y51)
C: bacillus licheniformis atcc 14580 (aka bacillus licheniformi... | [H; B] |
<Instruct>: Given the context 'Crude protein extracts of E. coli strain BL21, carrying the empty plasmid (pET28nHis6) or pME20 (pET28nHis6-SA1665) which expressed nHis6-SA1665 upon induction with IPTG, were incubated with the 161-bp biotinylated-DNA fragment previously used as bait in the DNA-binding protein assay.', s... | <Mentions>: [e. coli strain bl21]
<Options>: A: pseudomonas aeruginosa bl21
B: escherichia coli strain bw2952 (aka escherichia coli bw2952)
C: escherichia coli bw25113 (escherichia coli strain bw25113) (aka escherichia coli bw25113)
D: escherichia coli bl21 (escherichia coli strain bl21) (aka escherichia coli bl21)
E: ... | [D] |
<Instruct>: Given the context 'Effect of SA1665 deletion on β-lactam resistance
To analyse the effect of SA1665 inactivation on methicillin resistance, nonpolar markerless deletions of SA1665 (Figure 1B) were constructed in a selection of clinical MRSA isolates, which varied in their genetic background, SCCmec type, an... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
C: staphylococcus pyoge... | [C] |
<Instruct>: Given the context 'Effect of SA1665 deletion on β-lactam resistance
To analyse the effect of SA1665 inactivation on methicillin resistance, nonpolar markerless deletions of SA1665 (Figure 1B) were constructed in a selection of clinical MRSA isolates, which varied in their genetic background, SCCmec type, an... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
B: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
C: staphylococcus aureu... | [E] |
<Instruct>: Given the context 'Discussion
Methicillin resistance in MRSA is primarily dependent on the presence of the mecA gene, however, resistance levels are generally governed by strain-specific factors including mecA regulatory elements and other chromosomal fem/aux factors which either enhance or repress the expr... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus str. mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
C: staphylococcus aureus m1
D: staph... | [E] |
<Instruct>: Given the context 'The impact of deleting SA1665 in MRSA was extremely strain specific, underlining the importance of the genetic background in governing the final methicillin resistance levels of MRSA, and demonstrating the large genomic variability between different strain lineages.
', select the correct... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
C: micrococcus pyogenes (aka staphylococcus aureus)
D: staphylococcus aureus subsp. aureus ... | [C] |
<Instruct>: Given the context 'Conclusion
SA1665 is a previously uncharacterised DNA-binding protein that has a negative effect on β-lactam resistance in MRSA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by ... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus m1
B: staphylococcus simulans staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
C: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
D: micrococcus pyog... | [D] |
<Instruct>: Given the context 'However, while nonpolar deletion of SA1665 was shown to increase oxacillin resistance levels in several heterogeneously resistant MRSA, its deletion had no effect on mecA transcription or PBP2a production.', select the correct biomedical concept for each mention using the provided options... | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
B: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
C: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureu... | [D] |
<Instruct>: Given the context 'The resulting plasmid, pME20, was transformed into E. coli BL21 for expression of recombinant nHis6-SA1665 protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli bl21]
<Options>: A: escherichia coli strain bl21 (aka escherichia coli bl21)
B: escherichia coli ec1868
C: escherichia coli bw25113 (escherichia coli strain bw25113) (aka escherichia coli bw25113)
D: pseudomonas aeruginosa bl21
E: escherichia coli bl21(de3) (escherichia coli strain bl21(de3)) (aka ... | [A] |
<Instruct>: Given the context 'To maximise the abundance of soluble protein produced, cultures were grown in osmotic shock medium at 37°C (1 g/l NaCl, 16 g/l tryptone, 10 g/l yeast, 1 M sorbitol, 10 mM betaine, modified from [33]) to an OD600 nm of 0.5, cooled briefly on ice, then induced by adding 100 μM IPTG and grow... | <Mentions>: [yeast]
<Options>: A: saccharomyceta
B: saccharomyces hansenii (aka debaryomyces hansenii)
C: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
D: saccharomyces albicans (aka candida albicans)
E: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces ... | [E] |
<Instruct>: Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 a... | <Mentions>: [e. coli; s. aureus]
<Options>: A: enterobacteriaceae bacterium
B: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
C: staphylococcus sp. s
D: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staph... | [H; F] |
<Instruct>: Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 a... | <Mentions>: [e. coli; s. aureus]
<Options>: A: staphylococcus staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
B: escherichia coli (strain b) (aka escherichia coli b)
C: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
D: staphylococcus pyogenes aureus (aka staphylococcus aureus... | [E; D] |
<Instruct>: Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 a... | <Mentions>: [e. coli; s. aureus]
<Options>: A: escherichia/shigella coli (aka escherichia coli)
B: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
C: staphylococcus (aurococcus) (aka staphylococcus)
D: escherichia coli (strain b) (aka escherichia coli b)
E: escherichia
F: escherichia faecalis ('... | [A; J] |
<Instruct>: Given the context 'PBP2a detection was performed using monoclonal PBP2a antibody (1:20000) from the MRSA-screen kit (Denka Seiken).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
B: micrococcus aureus (aka staphylococcus aureus)
C: staphylococcus simulans staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
D: staphylococcus aureus subsp... | [B] |
<Instruct>: Given the context 'The Caenorhabditis elegans genome contains monomorphic minisatellites and simple sequences.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caenorhabditis elegans]
<Options>: A: polyzonia elegans
B: myzomyia elegans (aka anopheles elegans)
C: rhabditis elegans (aka caenorhabditis elegans)
D: caenorhabditis
E: caenorhabditis sp.
F: None of the above. | [C] |
<Instruct>: Given the context 'Here we demonstrate the presence of sequences in the genome of the nematode Caenorhabditis elegans which are homologous to two sets of short sequence DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [caenorhabditis elegans]
<Options>: A: caenorhabditis sp.
B: rhabditis elegans (aka caenorhabditis elegans)
C: enyo elegans (aka zodarion elegans)
D: myzomyia elegans (aka anopheles elegans)
E: polyzonia elegans
F: None of the above. | [B] |
<Instruct>: Given the context 'Images
Volume 17 Number 23 1989 Nucleic Acids Research
The Caenorhabds elegans genome contains monomorphic minisatellites and simple sequences Andrd G.Uitterlinden, P.Eline Slagboom, Thomas E.Johnsonl and Jan Vijg
Department of Molecular Biol... | <Mentions>: [caenorhabds elegans]
<Options>: A: rhabditis elegans (aka caenorhabditis elegans)
B: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
C: theocolax elegans
D: polyzonia elegans
E: aplysinopsis elegans
F: None of the above. | [A] |
<Instruct>: Given the context 'Here we demonstrate the presence of sequences in the genome of the nematode Caenorhabditis elegans which are homologous to two sets of short sequence DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for e... | <Mentions>: [caenorhabditis elegans]
<Options>: A: drosophila elegans
B: uronema elegans
C: uca elegans (aka tubuca elegans)
D: cyclostrongylus elegans
E: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
F: None of the above. | [E] |
<Instruct>: Given the context 'Here we demonstrate that the genome of the nematode Caenorhabditis elegans contains sequences that are homologous to the minisatellite core sequence 33.6 (1) and to the simple sequence motif (AGC)n.', select the correct biomedical concept for each mention using the provided options. Answe... | <Mentions>: [caenorhabditis elegans]
<Options>: A: theocolax elegans
B: elegans subgroup (in: flies)
C: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
D: cyclostrongylus elegans
E: gongylostoma elegans elegans (clausilia elegans elegans) (aka gongylostoma elegans elegans)
F: None of the above. | [C] |
<Instruct>: Given the context 'Surprisingly, these sequences did not display polymorphism when two independent C. elegans strains, Bristol and Bergerac, were compared.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, s... | <Mentions>: [c. elegans]
<Options>: A: cyclostrongylus elegans
B: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
C: caenorhabditis
D: rhabditis elegans (aka caenorhabditis elegans)
E: uronema elegans
F: None of the above. | [D] |
<Instruct>: Given the context 'Nucleic Acids Research
C. elegans
N 0$ 8
_ _
: , s , ..e :*. ,~ :::::
.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: myzomyia elegans (aka anopheles elegans)
B: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
C: theocolax elegans
D: rhabditis elegans (aka caenorhabditis elegans)
E: uca elegans (aka tubuca elegans)
F: None of the above. | [D] |
<Instruct>: Given the context 'I and Eco RI digested genomic DNA isolated from the two C. elegans strains Bristol (N) and Bergerac (B).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: zodarion elegans (enyo elegans) (aka zodarion elegans)
B: rhabditis elegans (aka caenorhabditis elegans)
C: caenorhabditis vulgaris (aka caenorhabditis remanei)
D: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
E: caromyxa elegans (aka mutinus ... | [B] |
<Instruct>: Given the context 'In Figure 1 the hybridization patterns are shown of C. elegans genomic DNA digested with Hae II, Rsa I and Eco RI, and subsequently hybridized to minisatellite core probe 33.6, the simple sequence probe (AGC)n and Tcl.', select the correct biomedical concept for each mention using the pro... | <Mentions>: [c. elegans]
<Options>: A: elegans subgroup (in: flies)
B: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
C: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
D: theocolax elegans
E: caenorhabditis drosophilae (rhabditis drosophilae) (aka c... | [B] |
<Instruct>: Given the context 'In Figure 1 the hybridization patterns are shown of C. elegans genomic DNA digested with Hae II, Rsa I and Eco RI, and subsequently hybridized to minisatellite core probe 33.6, the simple sequence probe (AGC)n and Tcl.', select the correct biomedical concept for each mention using the pro... | <Mentions>: [c. elegans]
<Options>: A: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
B: theocolax elegans
C: elegans subgroup (in: flies)
D: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
E: None of the above. | [E] |
<Instruct>: Given the context 'However, identical hybridization patterns for the two strains with the three enzymes tested indicated that in C. elegans these sequences are monomorphic (Fig. 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, o... | <Mentions>: [c. elegans]
<Options>: A: zodarion elegans (enyo elegans) (aka zodarion elegans)
B: rhabditis elegans (aka caenorhabditis elegans)
C: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
D: caenorhabditis sp.
E: elegans subgroup (in: mosquitos)
F: None of the above. | [B] |
<Instruct>: Given the context 'Based on the number of hybridizing bands we estimate the C. elegans genome to contain about 30 33.6 homologous loci and about 20 (AGC)n homologous loci.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for... | <Mentions>: [c. elegans]
<Options>: A: enyo elegans (aka zodarion elegans)
B: elegans subgroup (in: mosquitos)
C: uronema elegans
D: rhabditis elegans (aka caenorhabditis elegans)
E: bactris elegans
F: None of the above. | [D] |
<Instruct>: Given the context 'It should be noted, however, that at least in humans, a substantial part of the minisatellites detected by core probes also displays high levels of monomorphism as analysed by cloning (1) or by two-dimensional DNA fingerprinting (5).
', select the correct biomedical concept for each me... | <Mentions>: [humans]
<Options>: A: birds (aka aves)
B: homo sapiens (human) (aka homo sapiens)
C: neanderthal man (aka homo sapiens neanderthalensis)
D: placental mammals (aka eutheria)
E: genus
F: None of the above. | [B] |
<Instruct>: Given the context 'Indeed, Eide and Anderson (7) showed that tandemly repeated duplications in the unc-54 gene of C. elegans revert at high frequencies.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separate... | <Mentions>: [c. elegans]
<Options>: A: caenorhabditis vulgaris (aka caenorhabditis remanei)
B: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
C: zodarion elegans (enyo elegans) (aka zodarion elegans)
D: theocolax elegans
E: elegans subgroup (in: mosquitos)
F: None of the above. | [B] |
<Instruct>: Given the context 'A more likely explanation for the monomorphic nature of the sequences detected with 33.6 and (AGC)n in C. elegans is selection against sequence variants at these loci.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected optio... | <Mentions>: [c. elegans]
<Options>: A: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
B: caenorhabditis
C: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
D: gongylostoma elegans elegans (clausilia elegans elegans) (aka gongylostoma elegans elegans)
... | [C] |
<Instruct>: Given the context 'An important step in understanding this phenomenon will therefore be the isolation and analysis of individual homologous minisatellite and simple sequence loci from a genomic library of C. elegans.
', select the correct biomedical concept for each mention using the provided options. An... | <Mentions>: [c. elegans]
<Options>: A: bactris elegans
B: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
C: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
D: enyo elegans (aka zodarion elegans)
E: caenorhabditis vulgaris (aka caenorhabditis remanei)
F: None ... | [B] |
<Instruct>: Given the context 'In the second study, adult (3–6 m) BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for... | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: peromyscus
C: mouse (aka mus musculus)
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: mouse (aka mus <genus>)
F: None of the above. | [C] |
<Instruct>: Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', select the correct biomedical concept f... | <Mentions>: [mice; escherichia coli]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: escherichia/shigella coli (aka escherichia coli)
C: escherichia phage
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: escherichia coli 1a
F: escherichia coli (strain b) (aka escherichia ... | [J; B] |
<Instruct>: Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', select the correct biomedical concept f... | <Mentions>: [mice; escherichia coli]
<Options>: A: bacterium coli (aka escherichia coli)
B: escherichia phage
C: house mouse (aka mus musculus)
D: escherichia coli 1a
E: mus <subgenus> (mus (aka mus <subgenus>))
F: unspecified coliform bacterium
G: mus domesticus (aka mus musculus domesticus)
H: escherichia coli b (esc... | [C; A] |
<Instruct>: Given the context 'In the final study, adult and aged BALB/c mice were treated with the same minocycline and LPS injection regimen and markers of neuroinflammation were determined.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, on... | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: western european house mouse (aka mus musculus domesticus)
C: mouse (aka mus musculus)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F:... | [C] |
<Instruct>: Given the context 'Moreover, minocycline facilitated the recovery from sickness behavior (i.e., anorexia, weight loss, and social withdrawal) and prevented anhedonia in adult mice challenged with LPS.', select the correct biomedical concept for each mention using the provided options. Answer by listing the ... | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus sp. (mice (aka mus sp.))
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [A] |
<Instruct>: Given the context 'Finally, in aged mice, where exaggerated neuroinflammation was elicited by LPS, minocycline pretreatment was still effective in markedly reducing mRNA levels of IL-1β, TLR2 and IDO in the hippocampus.
', select the correct biomedical concept for each mention using the provided options. A... | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: house mouse (aka mus musculus)
C: mice (aka mus <genus>) (aka mus <genus>)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Moreover, in the brain of rats, minocycline abrogates microglial expression of CD11b and MHC II through a protein kinase-c dependent mechanism [45].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each me... | <Mentions>: [rats]
<Options>: A: rattus norvegicus albus
B: rats (aka rattus norvegicus) (aka rattus norvegicus)
C: rattus sp. (rats (aka rattus sp.))
D: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
E: black rat (aka rattus rattus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Moreover, our data show that minocycline pretreatment attenuated LPS-induced weight loss, social withdrawal, and anhedonia in adult mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, sepa... | <Mentions>: [mice]
<Options>: A: mus (aka mus <genus>) (aka mus <genus>)
B: mus castaneus (aka mus musculus castaneus)
C: mus musculus (house mouse) (aka mus musculus)
D: eastern european house mouse (aka mus musculus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [C] |
<Instruct>: Given the context 'The attenuation of sickness behavior was paralleled with minocycline dependent decrease in markers of neuroinflammation (IL-1β, TLR2, and IDO) in adult and aged mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected option... | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: peromyscus
C: mus musculus (house mouse) (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Methods
Animals
Male BALB/c mice, adults (3 month old) and juvenile (3–4 week old) were purchased from Harlan (Indianapolis, IN).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by... | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: peromyscus
C: mus <genus> (mice (aka mus <genus>))
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | [A] |
<Instruct>: Given the context 'For age comparisons, male BALB/c mice (3–4 and 20–22 month old) were purchased from the National Institute on Aging specific pathogen free colony.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each ment... | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mice (aka mus sp.) (aka mus sp.)
C: mus musculus (house mouse) (aka mus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | [C] |
<Instruct>: Given the context 'Upon arrival, mice were individually housed in polypropylene cages and maintained at 21°C under a 12 h light: 12 h dark cycle with ad libitum access to water and rodent chow.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selecte... | <Mentions>: [mice]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mus musculus (house mouse) (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: peromyscus
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Upon arrival, mice were individually housed in polypropylene cages and maintained at 21°C under a 12 h light: 12 h dark cycle with ad libitum access to water and rodent chow.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selecte... | <Mentions>: [mice]
<Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: peromyscus
D: mus sp. (mice (aka mus sp.))
E: None of the above. | [E] |
<Instruct>: Given the context 'At the end of each study, mice were examined postmortem for gross signs of disease (e.g., splenomeglia or tumors).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mouse (aka mus musculus)
B: peromyscus
C: mus sp. (mice (aka mus sp.))
D: mus (aka mus <genus>) (aka mus <genus>)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | [A] |
<Instruct>: Given the context 'Data from mice determined to be unhealthy were excluded from analysis (< 5%).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mice (aka mus <genus>) (aka mus <genus>)
C: house mouse (aka mus musculus)
D: peromyscus
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [C] |
<Instruct>: Given the context 'Mice were euthanized by CO2 asphyxiation and whole brains were collected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus sp. (mice (aka mus sp.))
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Sucrose preference
To assess sucrose preference, mice were provided two solutions, water or water supplemented with 2% sucrose, in 50 ml conical tubes with stoppers fitted with ball-type sipper tubes.', select the correct biomedical concept for each mention using the provided options. Ans... | <Mentions>: [mice]
<Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mouse (aka mus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: peromyscus
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Prior to testing conditions, all mice were acclimated to the two bottle test choice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mus castaneus (aka mus musculus castaneus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: m... | [E] |
<Instruct>: Given the context 'All mice drank both the water and the 2% sucrose solution, but preferred drinking the sucrose over the water (data not shown).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: mus musculus (house mouse) (aka mus musculus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | [B] |
<Instruct>: Given the context 'On the day of testing, mice were fluid and food deprived for 2 h prior to testing [50].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus <genus> (mice (aka mus <genus>))
C: mus castaneus (aka mus musculus castaneus)
D: house mouse (aka mus musculus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In brief, mice were euthanized by CO2 asphyxiation and blood was collected by cardiac puncture into EDTA coated syringes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicol... | <Mentions>: [mice]
<Options>: A: mouse (aka mus <genus>)
B: mus musculus (house mouse) (aka mus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: peromyscus
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [B] |
<Instruct>: Given the context 'For all mouse studies, minocycline (Sigma, St. Louis, MO) was dissolved in sterile water and sonicated to ensure complete solubilization.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, sepa... | <Mentions>: [mouse]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: western european house mouse (aka mus musculus domesticus)
C: mouse (aka mus <genus>)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | [A] |
<Instruct>: Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one f... | <Mentions>: [mouse; mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: mus <genus> (mice (aka mus <genus>))
C: peromyscus
D: mus molossinus (aka mus musculus molossinus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: eastern european house mouse (aka mus musculus m... | [H; H] |
<Instruct>: Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one f... | <Mentions>: [mouse; mice]
<Options>: A: mice (aka mus sp.) (aka mus sp.)
B: peromyscus
C: mus molossinus (aka mus musculus molossinus)
D: mus castaneus (aka mus musculus castaneus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: mus <genus> (mice (aka mus <genus>))
G: mouse (aka mus musculus)
H: None of the above. | [G; G] |
<Instruct>: Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; escherichia coli]
<Options>: A: escherichia
B: peromyscus
C: house mouse (aka mus musculus)
D: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: mus (aka mus <subgenus>) (aka mus <subgenus>)
G: enterobacter... | [C; I] |
<Instruct>: Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; escherichia coli]
<Options>: A: escherichia sp.
B: enterobacteria (aka enterobacteriaceae)
C: mus cricetus (aka cricetus cricetus)
D: escherichia coli (strain b) (aka escherichia coli b)
E: unspecified coliform bacterium
F: peromyscus
G: mice (aka mus <genus>) (aka mus <genus>)
H: mus musculus (house... | [H; I] |
<Instruct>: Given the context 'The LPS dosage was selected because it elicits a proinflammatory cytokine response in the brain resulting in mild transient sickness behavior in adult mice [13,53].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options,... | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: western european house mouse (aka mus musculus domesticus)
D: mice (aka mus sp.) (aka mus sp.)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [A] |
<Instruct>: Given the context 'In the second study, adult male BALB/c mice received an i.p. injection with vehicle or minocycline for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by se... | <Mentions>: [mice]
<Options>: A: peromyscus
B: mus castaneus (aka mus musculus castaneus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus <genus> (mice (aka mus <genus>))
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | [C] |
<Instruct>: Given the context 'In a related, but separate study, adult mice were treated with minocycline and LPS as described and anhedonia was assessed 24–39 h following i.p. injection of saline or LPS (0.33 mg/kg) (n = 15).', select the correct biomedical concept for each mention using the provided options. Answer b... | <Mentions>: [mice]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus cricetus (aka cricetus cricetus)
D: peromyscus
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [A] |
<Instruct>: Given the context 'In a related, but separate study, adult mice were treated with minocycline and LPS as described and anhedonia was assessed 24–39 h following i.p. injection of saline or LPS (0.33 mg/kg) (n = 15).', select the correct biomedical concept for each mention using the provided options. Answer b... | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: mus cricetus (aka cricetus cricetus)
C: peromyscus
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: None of the above. | [E] |
<Instruct>: Given the context 'In the third study, adult BALB/c mice were treated with minocycline and then LPS as described.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: house mouse (aka mus musculus)
F: None of the above... | [E] |
<Instruct>: Given the context 'Mice were euthanized by CO2 asphyxiation 4 later.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: peromyscus
B: mus castaneus (aka mus musculus castaneus)
C: western european house mouse (aka mus musculus domesticus)
D: mice (aka mus <genus>) (aka mus <genus>)
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'In a final study, adult (3–4 month old) or aged (20–22 month old) male BALB/c mice were treated with minocycline and LPS as described and euthanized 4 h later.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one ... | <Mentions>: [mice]
<Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: house mouse (aka mus musculus)
D: mus castaneus (aka mus musculus castaneus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [C] |
<Instruct>: Given the context 'LPS-induced TLR2 surface expression on microglia is reduced by minocycline
Because minocycline attenuated LPS-induced cytokine secretion and TLR2 mRNA expression in BV-2 cells we next sought to determine if minocycline suppresses markers of microglial activation in the brain of mice.', se... | <Mentions>: [mice]
<Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus castaneus (aka mus musculus castaneus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus cricetus (aka cricetus cricetus)
E: mus musculus (house mouse) (aka mus musculus)
F: None o... | [E] |
<Instruct>: Given the context 'Mice were injected i.p.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus cricetus (aka cricetus cricetus)
D: mouse (aka mus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In this experiment, adult mice were treated with minocycline and LPS as described.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: house mouse (aka mus musculus)
E: mice (aka mus <genus>) (aka mus ... | [D] |
<Instruct>: Given the context 'For example, at 8 h post LPS, social exploration was reduced by 35% in minocycline pretreated mice given LPS compared to a 67% reduction in vehicle pretreated mice given LPS (P < 0.001).', select the correct biomedical concept for each mention using the provided options. Answer by listing... | <Mentions>: [mice]
<Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mus domesticus (aka mus musculus domesticus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mouse (aka mus musculus)
E: mouse (aka mus <genus>)
F: None of the above. | [D] |
<Instruct>: Given the context 'While minocycline administration alone reduced food intake and body weight in control mice (P < 0.05, for each), it also protected against LPS-associated anorexia (Mino × LPS interaction, F(1, 60)', select the correct biomedical concept for each mention using the provided options. Answer ... | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mouse (aka mus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus <genus> (mice (aka mus <genus>))
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [B] |
<Instruct>: Given the context 'In this experiment, mice were subjected to the same minocycline injection regimen and LPS challenge as above and sucrose preference was assessed 24–39 h post LPS injection.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected ... | <Mentions>: [mice]
<Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus musculus (house mouse) (aka mus musculus)
D: peromyscus
E: mice (aka mus <genus>) (aka mus <genus>)
F: None of the above. | [C] |
<Instruct>: Given the context 'By 24 h post LPS injection, food and water intake returned to baseline and LPS treated mice still exhibited a marked reduction in sucrose preference from 24–39 h (F(1,59) = 14.3, P < 0.003).', select the correct biomedical concept for each mention using the provided options. Answer by lis... | <Mentions>: [mice]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mus <genus> (mice (aka mus <genus>))
C: mus domesticus (aka mus musculus domesticus)
D: mus cricetus (aka cricetus cricetus)
E: mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'By 24 h post LPS injection, food and water intake returned to baseline and LPS treated mice still exhibited a marked reduction in sucrose preference from 24–39 h (F(1,59) = 14.3, P < 0.003).', select the correct biomedical concept for each mention using the provided options. Answer by lis... | <Mentions>: [mice]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus sp. (mice (aka mus sp.))
C: mus domesticus (aka mus musculus domesticus)
D: mus cricetus (aka cricetus cricetus)
E: None of the above. | [E] |
<Instruct>: Given the context 'For example, minocycline pretreated mice injected with LPS maintained the same strong preference for sucrose as saline and minocycline controls (i.e., approximately 85% preference).', select the correct biomedical concept for each mention using the provided options. Answer by listing the ... | <Mentions>: [mice]
<Options>: A: western european house mouse (aka mus musculus domesticus)
B: peromyscus
C: house mouse (aka mus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [C] |
<Instruct>: Given the context 'In this experiment, mice were subjected to the minocycline injection regimen and LPS challenge as above and cytokine mRNA levels were determined in the cortex and hippocampus 4 h after LPS injection.', select the correct biomedical concept for each mention using the provided options. Answ... | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus musculus (house mouse) (aka mus musculus)
D: eastern european house mouse (aka mus musculus musculus)
E: peromyscus
F: None of the above. | [C] |
<Instruct>: Given the context 'In mice pretreated with vehicle, LPS markedly increased IL-1β mRNA levels in the hippocampus (F(1,31)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mouse (aka mus musculus)
B: mus (aka mus <genus>) (aka mus <genus>)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: peromyscus
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [A] |
<Instruct>: Given the context 'The LPS-induced IL-1β mRNA expression was reduced in both brain regions in mice receiving minocycline prior to LPS injection: (hippocampus, F(1,31)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each men... | <Mentions>: [mice]
<Options>: A: mouse (aka mus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: peromyscus
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [A] |
<Instruct>: Given the context 'It is important to note that IDO mRNA was undetected in saline treated mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <genus>) (aka mus <genus>)
B: peromyscus
C: house mouse (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | [C] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.